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The Milk Check
Valley Queen on casein vs. whey. Plus, where whey goes from here.

The Milk Check

Play Episode Listen Later Dec 28, 2025 27:54


In this episode of The Milk Check, Ted Jacoby III welcomes Lloyd Metzger and TJ Jacoby of Valley Queen Cheese Company for a deep dive into the science, functionality and future of dairy proteins. The conversation starts at the molecular level – the difference between casein and whey – and builds toward the real-world implications for product developers, processors and nutrition brands. We cover: Why casein is built to carry calcium (and whey isn’t) How heat and pH change protein behavior Fast versus slow digestion and why both matter The role of whey protein in muscle maintenance, aging and GLP-1 nutrition What pro cream really is and why its value may be underestimated Why cellular agriculture is more niche than threat If you work in dairy, food formulation or nutrition, this is a protein conversation worth digesting. Got questions? We'd love to hear them. Submit below, and we might answer it on the show. Ask The Milk Check TMC-Intro-final[00:00:00]Ted Jacoby III: Hi everybody, and thank you for joining us today for this very special recording of the Milk Check Podcast. Today, our topic is: what is the future of dairy proteins? And we have two very special guests. The first is Lloyd Metzger, VP of Quality and Technical Services for Valley Queen Cheese Company, and formerly Professor of Dairy Science at South Dakota State University. And the second, particularly special to me, is my son TJ Jacoby, Whey Technologist for Valley Queen. A South Dakota State graduate. Someone who has been interested in dairy proteins since his first biology class in high school. Guys, thank you for joining us today and welcome to The Milk Check. Lloyd Metzger: Glad to be here. TJ Jacoby: Good to be on, Dad. Ted Jacoby III: It’s December 18th, 2025. Milk production in the US is up 4%. Milk production in Europe is up something similar. Milk production in New Zealand is up. Milk production in Argentina is up. We are definitely in an [00:01:00] environment today where the supply of milk and dairy is overwhelming demand, at least for the moment. Cheese prices are near historical lows. Butter prices are near historical lows. Nonfat milk, skim milk powder prices are on the low end of the range. This market is a market that feels heavy, and I think most people out there would say, it almost feels like even though we’re at lows, we may actually go lower before we go higher. And yet, on the other hand, there are whey proteins, Josh, if I’m not mistaken, whey proteins just hit historical highs. Josh White: Maybe the highest prices we’ve ever seen for whey protein isolate and WPC 80. Ted Jacoby III: So, we have an environment where the demand on the protein side is extremely strong, and the trends on protein consumption are extremely strong and really feel like they’re gonna be around for quite some time. We’ve got baby boomers retiring and whether it’s because of GLP-1s or it’s just a general knowledge and understanding of what human nutritional needs are as people age, they know that they need more protein in their [00:02:00] diet. So, it begs the question: what is going on with dairy proteins and whey proteins and how is this going to evolve in such a unique market where demand is so strong for protein right now? And so, I’m gonna ask the question first. What’s the difference at a molecular level between whey proteins and milk proteins? Because when we’re in an environment like we are now, where you’ve got the demand really, really high, you also have a market that’s gonna start looking for alternatives, simply because prices are so high. What is the difference between milk proteins in general and whey protein specifically? Lloyd Metzger: It’s important to talk about from a functional perspective how the proteins are different. I’m sure we’ll get into the nutritional differences between those proteins as well. It’s important to understand what’s driving those differences in functional characteristics. And it’s really all about calcium. The casein system is designed to carry calcium. The whey protein system is not designed to carry calcium. That differentiates the two groups of [00:03:00] proteins and makes their properties very different. TJ Jacoby: I’ll explain it like this. Milk proteins, there’s two classes of proteins, right? There’s casein and then there’s whey. The casein is used to make cheese, and then the whey protein is what comes off. So, the whey protein is everything that is not used to make cheese. So, the reason why casein proteins works so well for cheese because those proteins like to fall together in these spheres, they like to stick to one another. They like to stick to one another ’cause they have certain groups that latch onto the calcium and then they bridge with phosphate. When they do, they have multiple proteins, different types of casein proteins that bridge together with phosphate and then based on their repulsion forces, they stick together. Calcium and phosphates really help it stick when we make cheese. The outside of that casein, micelle, that ball, when we make cheese, that outside is stripped off, it becomes hydrophobic, and that causes those spheres to stick together. That’s a huge functional property of casein. Whey [00:04:00] protein is the opposite. Whey protein is really hydrophillic. It’s very polar. So, they like to float around in solution and stay floating around in solution. And they don’t like casein. It likes to stay separate from casein. And so, when you make cheese, it readily is released into the whey stream because it likes to stick with the water. In the same way, those kind of stick together with these sulfur groups. But when you heat it up, they unfold. And when they unfold, now there’s certain reactions that can take place. So, those are the two major differences between casein and whey. Lloyd, what did I miss? Lloyd Metzger: I would try to simplify it a little bit. The difference between casein and whey protein is casein is what’s trapped when we make cheese. And whey protein is the soluble protein that’s left over in the water phase of cheese. Cheese making is a dehydration process. We concentrate the fat and protein that’s in milk, the casein version of protein in milk. But you gotta look at the properties of those two [00:05:00] systems and the groups of protein. So, the casein protein is actually really stable to heat, but it is not stable to pH. So, casein will always coagulate at low pH. So, you lower the pH of milk, you get a yogurt-like product. That’s all the casein that’s coming out of the system. Whey proteins don’t mind a low pH, and they’ll stay soluble at a wide range of pH. But now, when you get to temperature, the complete opposite happens. Casein can handle super high temperatures and be very stable. Whey proteins can not handle high temperature at all, they start to gel. I think it’s important to look at the two different groups. Now you get into the functional differences between those two and the very different properties you have between those. Lloyd Metzger: That’s why you get all these products that are very different from each other. Why cheese is so much different than whey protein. And then you have these dairy products that are a combination that have the two together. So like when we make yogurt, we end up with the two products together and get this property that’s partway in between the two proteins. Ted Jacoby III: [00:06:00] Based on what you’re describing, when we’re talking about milk proteins, MPC 80, for example, there’s a higher level of calcium, I take it in milk proteins than compared to whey proteins. Is that true? Lloyd Metzger: Absolutely, but let’s remind everybody: milk protein is both casein and whey protein together at the normal ratio that’s in milk. So, of the protein, 80% is casein, 20% is whey protein. So, when you say milk protein, you’re actually meaning 80% casein and 20% whey protein. Now, when we talk about cheese or casein, we’re basically a hundred percent casein and 0% whey protein. Now, when we talk about whey protein, we’re essentially a 100% whey protein, no casein except for one fragment of casein that actually gets solubilized, as TJ described, and now actually becomes part of whey protein. Something that a lot of people don’t understand is that about 15% of what we call whey protein is actually a piece of casein that gets lost in the whey and now gets [00:07:00] captured and harvested in the whey protein manufacture process. But again, it’s important to remember milk protein is a 80 / 20 combination of casein and whey protein together. So, when you’re talking about milk protein, you’re actually talking about whey protein and casein together. Ted Jacoby III: It’s funny, I just learned something never really quite had my head around, and that’s that 80 / 20 ratio, that 80% of all the protein in milk is actually either alpha or beta casein. Correct? Lloyd Metzger: There’s actually four different casein fractions that are involved that make up that 80% of the total protein. Ted Jacoby III: Okay. The casein molecule isn’t really any bigger than most of the whey protein molecules, but they tend to clump together in those micelles. And so, they act as one big humongous mass compared to whey proteins. Correct? TJ Jacoby: Whey proteins may be collected like in pairs like two at a time, but casein proteins, there’s hundreds, right? Lloyd, that will just clump together. Thousands. TJ Jacoby: So, these spheres are absolutely massive protein complexes, but in fact there are a lot of little individual [00:08:00] proteins that make it up and they’re all bridged together with calcium and phosphate. Lloyd Metzger: It’s a packaging system that was designed to package up calcium and phosphorus. So, the whole casein system was designed by nature as a delivery vehicle for calcium and phosphorus, because calcium is not soluble by itself. Calcium phosphate is essentially rock. It’s the material that makes up eggshells. Think, think about a ground up eggshell that calcium phosphate complex is not soluble and it will sink to the bottom of your container of milk if you didn’t have the protein complex to hold it in solution. The analogy I use is it’s basically a kidney stone. Think about how much fun milking a cow would be if all the calcium and phosphorus was in the form of a kidney stone as you’re trying to milk the cow. All that calcium and phosphorus can be solubilized with the casein system and put it into solution and then make it so you can deliver that in a nutritional product. Ted Jacoby III: That makes perfect sense. That’s really cool. I think you guys also already touched on the differences in solubility as you were [00:09:00] describing the different proteins. But there’s differences in digestibility as well. What’s the source of that difference? TJ Jacoby: I’ll take this one. Returning back to the infant stage, I feel like we could set this up in light of why nature created these proteins. Dairy is the fundamental human food for infants. You have babies that can live up to a year off of just their mother’s milk. All the proteins that are found in there, those building blocks to grow an infant, can be boiled down to those two protein streams: whey protein and casein protein. The purpose of the casein protein for the infants is it’s fast acting. It’ll go right into the gut, and the gut is full of enzymes, but also really, really low pH, so low that it actually causes even those whey proteins to unfold. And It allows the stomach enzymes to break it up super, super fast and be absorbed. It’s considered one of the most bioavailable proteins known to man. It’s designed for that, that’s why nature created whey protein. Well, whey protein itself is also very nutritious. It has one of the highest concentrations of [00:10:00] essential amino acid, and the second highest known to man of branch-chain amino acids. That means it doesn’t have to be processed through the liver before it can be used by the human body. If your body’s actively using and consuming protein whey protein’s really good because it can be absorbed into your system and go right to the muscles. 33% of your muscle is branched chain amino acid. That’s what’s getting broken down while you’re working out. And then in the elderly, that’s what’s getting broken down that’s causing some muscle degeneration. Whey protein can help fortify that very quickly. However, all protein that is consumed in the body could also easily be processed through the liver with time. And so, if you have time, that’s where the casein comes into play. The casein, when it hits that acidic environment in the gut, it immediately clumps together. It actually creates cheese curds in the gut. And the reason why that’s so important is it slows down digestion so that slowly over time, that will be absorbed into the system. So it’s not [00:11:00] like a rush of energy right after the baby eats and then it goes away right away. Instead, it slows it down. The casein itself also likes to trap other nutrients. The casein in the gut will house the fat and the vitamins and the nutrients so that it’s slowly absorbed over the course of the next few hours before the baby’s next feeding. Ted Jacoby III: As a result of those digestibility differences, what are the differences in the amino acid profiles between casein and whey proteins? The body’s gonna need to break down most of that casein in order to absorb it. When the body breaks down that casein, what are the differences in the way that it absorbs some of those amino acid profiles and short-chain protein strands from the casein versus what’s readily bioavailable from the whey proteins? TJ Jacoby: Casein does not have the same percentage of those essential amino acids. It’s not as high, but it’s designed to be slow absorbing. Protein itself, it almost doesn’t matter the amino acid structure, as long as your body has enough of those vitamins and nutrients to absorb and to restructure it to [00:12:00] a different protein within the liver — that’s what your body needs. Most of us, the protein doesn’t have to be fast-acting. It’s not like our muscles are actively breaking down all the time. It can slowly be absorbed, be processed through the liver, and then used for almost any other function as long as we have all the vitamins and minerals that we need. Lloyd Metzger: Part of this huge shift we’re seeing in demand for protein, especially whey protein, this started 25, 30 years ago with bodybuilders and wanting to build muscle mass. And the realization that TJ mentioned: branch-chain amino acids are very important if you wanna rapidly put muscle mass on. It is also very important if you’re elderly or if you have sarcopenia where you’re starting to lose muscle mass. In those nutritional states, it’s really important to have high-level branch-chain amino acids, so you can put muscle on. Or if you’re on a GLP-1 medication where you’re not gonna be able to eat very much, you need a very efficient source of protein to build muscle mass. So there’s certain nutritional states where it is important to have branch-chain amino acids [00:13:00] and be able to get those from a protein like whey protein that has ’em at a very high level. But for the normal person, it’s not really all that relevant. You could get the protein you need from any protein that provides all the essential amino acids. Now, most plant proteins don’t do that. We’re talking about the difference between casein and whey protein. Both of them are an order of magnitude higher in nutritional quality than plant proteins because they have all the essential amino acids. And to TJ’s point, as long as you have the essential amino acids, the body can produce the non-essential amino acids from those essentials. Essential ones are amino acids the body can’t produce. You have to have those in the food you’re consuming to be able to produce the components you need. Josh White: We’ve got listeners from the dairy side of the equation and listeners from the utilization side that are making different products. And some of those customers are currently faced with the reality that a part of the equation for their adoption of whey proteins as an ingredient has shifted. The competition level’s very [00:14:00] high. They’re having more difficulty accessing some of it. And the price has changed quite a bit. And I think that when you’re talking about these products going into CPG applications as a lower inclusion rate ingredient, but with a lot of label power, being able to put whey protein, for instance, on that label, there’s several of them out there that are struggling to determine what the functional differences might be between the various dairy proteins. And what I’m afraid that is happening is some of these companies that are on the lower end of the value scale and can’t afford to keep up with all of the great products that are demanding whey protein or even milk protein, are gonnastart exploring alternatives outside of our space. and I think that we don’t want that, right? And what we’re seeing is this popularity of whey protein is driving a lot of customers for R&D projects to be asking us specifically for whey protein. And so help us understand what applications might make sense to use one, the other, or both. Lloyd Metzger: It completely depends on the product that [00:15:00] you’re after and the characteristics of the product that you want. Something like a beverage can go two different directions. So, if you’re gonna retort the beverage and put a lot of heat on it, you can’t do that with most whey proteins. They’re gonna gel. The most comparable protein to whey protein would be an egg protein. And everybody understands what happens when you heat eggs; they turn into a gel. So, whey proteins will happily do that. If you have a high enough concentration and you expose them to enough heat. Casein actually helps to protect whey protein from that coagulation. A lot of these high-protein beverages, they’re oftentimes a combination of casein and whey protein. They might alter the ratio a little bit from the 80 / 20. They might bump the whey protein up a little bit and have a 60 / 40 casein to whey protein. And so you’ll see ranges in that ratio of casein to whey protein, depending on the characteristics of the product that you’re actually after. The heat is a big piece of that. And then we go to pH as a big piece of what changes the functionality of casein to whey protein and makes you [00:16:00] change those ratios. Yogurt is another great example. You’ve got these super, super high-protein yogurts and a lot of cases they fortified with quite a bit of whey protein to be able to have more protein and still have the characteristics that you want in that product. In the protein bars, there’s all kinds of whey proteins there. In that application, you actually don’t even solubilize the protein. There’s hardly any water in that bar. It’s really almost a dry protein that has a plasticizer with it, some carbohydrates that actually make that edible. You’re almost eating a dry product. There’s a lot of food chemistry that goes into which product category you’re putting it in. There’s not this straight fast rule that you use whey proteins in this, you use casein and that. It depends on what food chemistry you use and how you put the blend together and then what processing you couple with that to get the characteristic that you’re actually after. Josh White: Can we spend a minute or two talking about the acidified products? They’ve gained a lot of popularity. The market potential is quite large. Can we talk a bit about the [00:17:00] differences between the clear WPIs and our traditional products? Lloyd Metzger: I wanna clarify the question. Are you talking specifically about whey protein only in the clear whey protein beverages versus the normal whey protein beverages? Ted Jacoby III: Yes. Lloyd Metzger: We really start to get into the weeds because we’ve got different whey products. So we’ve got whey protein concentrate. And then that comes in various forms. WPC 34 or WPC 80 are the most common. The 80 and the 34 correspond to how much protein on a dry basis those two products have. And they have whey proteins in the normal ratio that would be in the starting whey. Then we get into a group of products called whey protein isolates. And whey protein isolates go through an additional manufacturing process that allows you to purify the protein further and they’ll have more than 90% protein on a dry basis. And you may start to alter the ratio of the various whey proteins that were present in the starting whey. Now, when [00:18:00] we get into the clear whey protein isolates, we really start to alter the ratio of the proteins that are in there. We’ll also start to change some of the mineral profile of the components that are in that product. And then when we use those isolates in a formulation, we gotta be careful about all the other ingredients ’cause they’re gonna have an impact on whether or not the product is actually clear and whether or not it can be stable to heat. So, you can actually make whey protein stable to heat by controlling the mineral profile and controlling some of the processing conditions. You’re now taking a category of dairy ingredient and you’re starting to use technology IP to be able to provide specific functional characteristics that aren’t normally part of that ingredient. All of these may be called the same thing, and the basic consumer has absolutely no idea what the differences between all these things are. And when they’re looking at a label, they’re probably looking for the word whey protein, and that’s all they’re looking for. Josh White: As we’ve seen the market tighten up, we’ve seen [00:19:00] more inquiries and exploration about the use of pro cream,also called WPPC, also called WPC 70, so many different names. Definitely, in our experience, there’s quite a uniqueness as we originate this product from different manufacturers. Perhaps we can talk a bit more about what this product is and how it differs from the other proteins in the complex. Lloyd Metzger: I talked about WPC 80. That’s just the normal whey protein that we concentrate out of whey. And then, I mentioned whey protein isolate. To convert WPC 80 to a whey protein isolate, you use a filtration step called microfiltration. And in that microfiltration step, you remove any protein that is interacting with fat and take that out of the system. So, if you start with a normal WPC 80 and we’re gonna change it into a WPI. We are gonna go through a microfiltration process and we’re gonna lose about 25% of the protein that was there and all of the fat that was there. And [00:20:00] we’re gonna make a WPI out of that. And that WPI is gonna have about 75% of the protein we started with. The protein that we harvest out of that is actually pro cream. pro cream is just a byproduct of converting WPC 80 into WPI, and it’s gonna have about 25% of the mass of the protein that you started with, and all of the fat that was in that starting WPC 80 material. So that’s why you see it called high-fat WPC 30, and if you dry that down, it’s about a WPC 60. You can take that and blend that with WPC 34. You can do all kinds of things with that ingredient. Manufacturers are always trying to find a home for that. ’cause you’ve got a very high value product that’s easy to market in WPI. Ted Jacoby III: Lloyd, that pro cream, our hunch is there’s a lot more value in that pro cream than the market currently has its head around. Lloyd Metzger: they’re the same proteins that are in WPI, they’re just interacting with a fat. Now the fat [00:21:00] is very unique in that there’s quite a bit of phospholipid fat in there. And so there’s a lot of literature and research being done on the potential health benefits for brain development of phospholipids for infants as well as elderly to help with memory retention and actually help to prevent some Alzheimer’s effects. So, you see some companies starting to market that component that they’ve isolated. I think there is a lot of potential value there. But we’re in the early stages of where that’s gonna go. And you have some companies leading the way that are producing very specialized pro cream type products that are being used in infant nutrition or elderly nutrition. TJ Jacoby: But Lloyd, how do those phospholipids affect the shelf life of pro cream? Lloyd Metzger: They don’t help. The phospholipids are unsaturated fats or partially unsaturated and unsaturated fats are very easy to oxidize, so if they’re not handled properly, you’ll get very stale and oxidized off flavors in the product. It’s something you gotta be careful of. Ted Jacoby III: Oxidized fats, [00:22:00] another way to call that. That’s rancid, right? Yes. Lloyd Metzger: On its way to rancid. Josh White: Another selling point that people will make of the benefits of pro cream are IgGs. Can you guys explain a bit more of what that is to the layman? Lloyd Metzger: So, immunoglobulin is a protein that’s also present in milk. It’s really high in colostrum. It’s at very low levels in milk about 72 hours after the cow was started milking, the levels drop way down, but there is still a low level there. Those immunoglobulins are a very large protein. So when you go through your WPI manufacturing process, they’re gonna partition with that fat and that protein portion that you’re capturing. So they’re gonna go in that pro cream. Looking at the composition of IgG in the different waste streams, you’ll find it’s elevated in that pro cream portion. Now I’d be a little concerned about what kind of shape that IgGs in because you’ve seen a lot of heat [00:23:00] and different manufacturing conditions through that process. So you’d really have to be careful about what kind of claims you’re making based on what kind of shape that IgGs in. Mm-hmm. TJ Jacoby: For an infant, those IgGs will go right into the bloodstream. It’s whole proteins, but for us, it actually has to break up the protein entirely before it can be absorbed into our system. So what kind of functional benefits does IgG bring for an adult? I’d be curious to see what that literature entails. Mike Brown (2): Over the last couple decades, DNA technology has been used more and more to produce valuable proteins, often for medical use like insulin. Are we gonna see a point with the cost benefit of that kind of technology we’ll reach where we can actually use that to produce these whey proteins rather than using a cow? Lloyd Metzger: There’s different levels of concern depending on the particular protein. An individual protein and an individual soluble protein like beta-lactoglobulin and alpha-lactalbumin that are in [00:24:00] whey, those have more potential to be produced in a fermentation type process. ’cause they’re an individual protein. You can over express it, you can get a lot of that produced. But when you get to the complexities of multiple proteins that are in whey, that’s when it really becomes uneconomical to do that from a fermentation standpoint. ’cause you’ve gotta produce all of those individually, try to put ’em together, then purify ’em. What people forget is how efficient the cow is. The cow is essentially a walking fermentation tank that feeds itself, controls its own temperature, cleans itself up. All you’ve gotta do is get the milk out of it. When you look at all the steps that go into the process and what it takes to produce it, it’s really hard to beat the efficiency of a cow. Ted Jacoby III: Lloyd, am I right in assuming that the threat of cellular agriculture to dairy would come in the development of specific protein chains and amino acids, but probably not in terms of the complete [00:25:00] protein profile that is delivered in milk proteins and whey proteins. Lloyd Metzger: Correct. And it would be the very high-end, expensive. So the lactoferrin. It would be your first one or some of the IgG, anything that is at low concentration and very high value. Because even if you did everything perfectly, you’re probably still talking $25 to $30 a pound in the manufacturer and isolation process. Well, we we’re really excited about $11 whey protein isolate. Right? You know, and that’s still half the price. Ted Jacoby III: Makes sense. Lloyd, TJ, this was an absolutely fantastic discussion. This was exactly what I wanted to get out of it. I can tell you I learned quite a bit today and I’m sure our listeners will too. Thank you so much for joining us. We really appreciate it. Lloyd Metzger: No problem. Happy to do it. TJ Jacoby: Truly special to be on today, Dad. I grew up listening to a lot of these podcasts, right? Now we’re here, now we’re on it together with you. So, no, it was truly special.[00:26:00]

Rare Disease Discussions
Chapter 7: Changes in Gene Therapy Programs to Lessons Learned from Recent Trials

Rare Disease Discussions

Play Episode Listen Later Dec 22, 2025 5:18


Julie A. Parsons, MD Haberfield Endowed Chair in Pediatric Neuromuscular DisordersProfessor of Clinical Pediatrics and NeurologyUniversity of Colorado School of Medicine, Children's Hospital ColoradoAurora, CO, USAHow have programs adapted to the experiences from clinical trials? I'm just looking at SMA because we've had SMA. We've had onasemnogene around for the longest period of time. We want to always confirm a diagnosis and know that the patient is right. We do antibody testing for these disorders prior to delivering the AAV therapies. We have to know that the product that is incredibly expensive is handled appropriately by the institution. Dealing with the pharmacy, making certain that you handle the agent properly, patients need to be pretreated at this point with prednisone, and that really has to happen so that you know that they're ready for treatment, that they don't have any infections prior to treatment.Then we need to monitor and provide medication and follow-up afterwards. As I said, I think this is really, really important to make sure that you're connected well with the patient. If you live in an area as we do, that has a huge catchment area with patients that come from hundreds of miles away, sometimes they need to stay with us for a period of time, so that we can ensure the safety and follow-up of these patients after we deliver gene therapies.Again, a recurring theme is the patients that you're treating who are not in a clinical trial are not the homogeneous, well-selected patients. It's really all actors. The population that you're treating commercially is very different. We're now moving into treating patients with larger body masses and older ages. We don't always know, because those patients haven't really been included in the clinical trials. We don't really know what some of the effects are going to be with that group of patients as well.I am a neurologist. I am not an immunologist. I have had to learn a lot of immunology at this point, but it's still not sufficient. I think that we also need to reach out to our subspecialist colleagues who really do have more experience than we do to try to help us with some of these issues, because as we look at these viral vector capsids and the transgenes, we have to say, is there something that we can do to mitigate the immune response that we're seeing when we're giving massive doses of these agents and really taxing the immune system in our patients?Looking at possibilities, we give steroids, and that's really what we've done. That was what was done in the early clinical trials with MENDEL. It's like, okay, prednisone, that's all we have to do is we give steroids and everybody will be fine. That really isn't maybe the answer. As we have more information, we know that we're going to start with steroids, but we're really going to look at, is there a way to block both the B-cell response, the T-cell response? Is there something that we can do so that we don't have to sit on the edge of our seats and not sleep for months after we treat these patients?At least in a trial, was done looking at patients who were treated just with corticosteroids. Those patients had rapid increases in IgM and IgG. There's complement activation. Both the adaptive and the acute immune responses are triggered. That's really what we're doing as standard practice right now, but in the trial looking at treating patients and pretreating patients with rituximab blocking B cells and sirolimus and corticosteroids, then no significant change in IgM, IgG.Is that something that we should be doing? I think that some of the clinical trials that are being set up are looking at instituting some of these immune-modulating features to see whether or not their outcomes are improved. Can we do anything proactively to prevent our patients from having some of these very severe events or fatalities? I think that's really what we need to be looking at now. I think we are looking at that as a community, and to me, is a story that is still unfolding in terms of how we keep our patients safe.In the next part, Doctors Beggs and Parsons will discuss key issues on gene therapy development.

The Cabral Concept
3599: Menstrual Cramping, Iron Deficiency, Maca Superfood, Asbestos Exposure, Mold Testing (HouseCall)

The Cabral Concept

Play Episode Listen Later Dec 13, 2025 14:51


Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Lisa: Hello- my 15 year old daughter gets really bad menstrual cramps. She is bed ridden and usually vomiting. Her PcP recommends 800mg of ibuprofen but I know that is treating the symptom and not the root cause. How do I determine the root cause and how to I get her some relief with putting her on birth control? Thanks a million!!     Gabriela: Hello! I've been an avid listener of your podcast for some time now, and have really learned a lot.  I was wondering if you know about Morley Robins and his beliefs about iron/deficiency. I listened to a podcast where he was guest and he said that pregnant women don't need iron even if their hemoglobin is low. He subtly connects iron fortification with hemorrhaging. Claims that a person needs only 1mg of iron daily from our diet, mentions RES, and says copper is much more important. Says we have ten times more iron in the tissue than the blood, so bloodwork isn't enough. Also says iron fortification should not be done. What is your opinion on all this? I'm confused.                        Rebecca: Hi Dr Cabral,  I love listening to you everyday and look forward to keeping up with your wonderful sharing of knowledge. I choose to listen to limited influential wellness experts and I value your opinions very much. I would like to know why you and others don't talk about maca as a valuable nutritional superfood. In the past I have read and listened to the value of this and am wondering why its not at the forefront anymore? Thank you very much. Rebecca                                                                                                                                                                 Victoria: Hi dr Stephen cabral, I have a tricky question that I'm hoping you can help me with. I have been a little worried about potential asbestos exposure. It's not a lot of exposure however someone told me that one exposure can lead to asbestiosis. I live a healthy life and wondering if there are lifestyle things I can do to keep my lungs healthy so it doesn't turn into an asbestos related disease. Everywhere I look on the internet doesn't really explain this. I am going to the gp as I have been extremely worried about this. Any help would be greatly appreciated. I have read your book and I saw in there it says that firefighters are exposed to more pollutants including asbestos and the book can really help with detox etc. Thank you for your time. Look forward to hearing from you! Victoria               Justine: I suspect there is mold behind the drywall of my 70 year old home. There was no caulk around the outdoor windows for 2 years and I started getting cognitive symptoms after moving in. My glutathione provoked urine mycotoxin test showed up positive for 3 mycotoxins but at low levels just over the limit. She said it's possible that I'm not detoxing well and my levels are actually underrepresented. She suggested I do the MyMycoLab blood IgG test next to confirm that mold is the cause of my severe MCAS. I am trying to determine if I should sell my home as I don't want to remediate. I work from home so this would be the only exposure source. Do you think this test is accurate for determining if mold is the cause of my symptoms?       Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3599 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

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The Moscow Murders and More
Mega Edition: Judge Judge Makes A Ruling On IGG Data (Part 1-2) (12/11/25)

The Moscow Murders and More

Play Episode Listen Later Dec 12, 2025 40:56 Transcription Available


IGG testing, also known as Immunoglobulin G testing, is a method used in forensic science to identify individuals through the analysis of specific proteins found in blood. Immunoglobulin G (IgG) is a type of antibody produced by the immune system in response to foreign substances, such as bacteria or viruses. Each person's IgG profile is unique, similar to a genetic fingerprint, making it useful for identification purposes.In crime-solving, IGG testing involves collecting blood samples from crime scenes and comparing them to known samples, such as those taken from suspects or victims. The presence or absence of specific IgG antibodies in the samples can help forensic investigators establish links between individuals and crime scenes.Police use IGG testing to:Establish connections between suspects and crime scenes: By comparing the IgG profiles of blood samples found at a crime scene with those of suspects or victims, investigators can determine whether a particular individual was present at the scene.Exclude innocent suspects: If the IgG profile of a suspect does not match that of the blood found at the crime scene, it can help exclude them from the investigation.Identify unknown individuals: In cases where the identity of a suspect or victim is unknown, IGG testing can be used to narrow down potential matches based on blood samples collected from the scene.However, like any forensic technique, IGG testing also raises privacy concerns. Some of these concerns include:Informed consent: Collecting blood samples for IGG testing without the individual's consent may raise ethical questions about privacy and bodily autonomy.Genetic information: IgG profiles can reveal information about an individual's immune system, which is a form of genetic information. There are concerns about how this sensitive data is collected, stored, and used, especially in terms of potential discrimination or misuse.False positives and misinterpretation: While IGG testing can be a valuable tool in forensic investigations, there is always a risk of false positives or misinterpretation of results. This could lead to wrongful accusations or convictions if not carefully considered.Database security: As with any forensic database, there are concerns about the security of the information stored within it. Unauthorized access or breaches could compromise individuals' privacy and potentially lead to misuse of their data.Ever since the arrest of Bryan Kohberger a conviction has rested upon the shoulders of the DNA that was collected at the scene of the brutal quadruple homicide. However, there have been challenges to the process used to collect that DNA and some have even questioned the constitutionality of the process itself. In this episode we take a look at that argument and hear from several legal scholars about the process that was used to collect the DNA and how that evidence will or will not be used moving forward.(commercial at 9:40)to contact me:bobbycapucci@protonmail.comsource:Moscow murder suspect could mount constitutional challenge | Idaho StatesmanBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Mega Edition: Judge Judge Makes A Ruling On IGG Data (Part 1-2) (12/11/25)

The Moscow Murders and More

Play Episode Listen Later Dec 11, 2025 25:02 Transcription Available


IGG testing, also known as Immunoglobulin G testing, is a method used in forensic science to identify individuals through the analysis of specific proteins found in blood. Immunoglobulin G (IgG) is a type of antibody produced by the immune system in response to foreign substances, such as bacteria or viruses. Each person's IgG profile is unique, similar to a genetic fingerprint, making it useful for identification purposes.In crime-solving, IGG testing involves collecting blood samples from crime scenes and comparing them to known samples, such as those taken from suspects or victims. The presence or absence of specific IgG antibodies in the samples can help forensic investigators establish links between individuals and crime scenes.Police use IGG testing to:Establish connections between suspects and crime scenes: By comparing the IgG profiles of blood samples found at a crime scene with those of suspects or victims, investigators can determine whether a particular individual was present at the scene.Exclude innocent suspects: If the IgG profile of a suspect does not match that of the blood found at the crime scene, it can help exclude them from the investigation.Identify unknown individuals: In cases where the identity of a suspect or victim is unknown, IGG testing can be used to narrow down potential matches based on blood samples collected from the scene.However, like any forensic technique, IGG testing also raises privacy concerns. Some of these concerns include:Informed consent: Collecting blood samples for IGG testing without the individual's consent may raise ethical questions about privacy and bodily autonomy.Genetic information: IgG profiles can reveal information about an individual's immune system, which is a form of genetic information. There are concerns about how this sensitive data is collected, stored, and used, especially in terms of potential discrimination or misuse.False positives and misinterpretation: While IGG testing can be a valuable tool in forensic investigations, there is always a risk of false positives or misinterpretation of results. This could lead to wrongful accusations or convictions if not carefully considered.Database security: As with any forensic database, there are concerns about the security of the information stored within it. Unauthorized access or breaches could compromise individuals' privacy and potentially lead to misuse of their data.Ever since the arrest of Bryan Kohberger a conviction has rested upon the shoulders of the DNA that was collected at the scene of the brutal quadruple homicide. However, there have been challenges to the process used to collect that DNA and some have even questioned the constitutionality of the process itself. In this episode we take a look at that argument and hear from several legal scholars about the process that was used to collect the DNA and how that evidence will or will not be used moving forward.(commercial at 9:40)to contact me:bobbycapucci@protonmail.comsource:Moscow murder suspect could mount constitutional challenge | Idaho StatesmanBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Wellness Mama Podcast
The Gut-Skin Connection: Why Clear Skin Starts Inside With Dr. Tyler Kruse

The Wellness Mama Podcast

Play Episode Listen Later Dec 8, 2025 41:18


Episode Highlights With TylerHow he got into gut and skin health work and his personal story with itPeeling skin on his fingertips led him to a deep dive into this topic Gut health shows up on the skin - if there are skin issues, something is going on underneathThe autoimmune connection and how almost everything can be resolved Looking at gut and diet and what IGG food allergies areA lot of people are constipated and don't realize it Key signs that an issue is more than just skin deepSurprising things related to autoimmune disease Why fast food is one of the worst things we can do for our digestion and health, and it isn't what you thinkThe biggest triggers he sees for skin issuesResources MentionedThe Wellness Way on X, on Facebook, and on InstagramDr. Tyler Kruse and The Wellness Way on InstagramThe Wellness Way Coralville

Beyond The Horizon
Mega Edition: Judge Hippler's Ruling On The Bryan Kohberger Digital Warrants (Part 5-6) (12/8/25)

Beyond The Horizon

Play Episode Listen Later Dec 8, 2025 28:43 Transcription Available


In Ada County Case No. CR01-24-31665, Defendant Bryan Kohberger filed motions to suppress evidence obtained through search warrants directed at AT&T, Google, USB devices, Apple, and Amazon. The defense argued that these warrants were invalid, alleging they were based on information gathered through unconstitutional methods, including the use of Investigative Genetic Genealogy (IGG), and that the affidavits supporting the warrants contained intentional or reckless omissions of material facts. They contended that the evidence obtained from these warrants violated Kohberger's Fourth Amendment rights and should therefore be excluded from trial.However, the court denied these suppression motions, ruling that the search warrants were lawfully issued and executed. The judge found that the affidavits provided sufficient probable cause and that the methods employed, including the use of IGG, did not violate constitutional protections. Additionally, the court determined that there was no evidence of intentional or reckless falsehoods or omissions in the affidavits that would warrant a Franks hearing. As a result, the evidence obtained from AT&T, Google, USB devices, Apple, and Amazon remains admissible in the proceedings against Kohbergerto contact me:bobbycapucci@protonmail.comsource:021925-Order-Defedants-Motions-Suppress-ATT-Google-USB-Apple-Amazon.pdf

Beyond The Horizon
Mega Edition: Judge Hippler's Ruling On The Bryan Kohberger Digital Warrants (Part 1-2) (12/7/25)

Beyond The Horizon

Play Episode Listen Later Dec 8, 2025 27:39 Transcription Available


In Ada County Case No. CR01-24-31665, Defendant Bryan Kohberger filed motions to suppress evidence obtained through search warrants directed at AT&T, Google, USB devices, Apple, and Amazon. The defense argued that these warrants were invalid, alleging they were based on information gathered through unconstitutional methods, including the use of Investigative Genetic Genealogy (IGG), and that the affidavits supporting the warrants contained intentional or reckless omissions of material facts. They contended that the evidence obtained from these warrants violated Kohberger's Fourth Amendment rights and should therefore be excluded from trial.However, the court denied these suppression motions, ruling that the search warrants were lawfully issued and executed. The judge found that the affidavits provided sufficient probable cause and that the methods employed, including the use of IGG, did not violate constitutional protections. Additionally, the court determined that there was no evidence of intentional or reckless falsehoods or omissions in the affidavits that would warrant a Franks hearing. As a result, the evidence obtained from AT&T, Google, USB devices, Apple, and Amazon remains admissible in the proceedings against Kohbergerto contact me:bobbycapucci@protonmail.comsource:021925-Order-Defedants-Motions-Suppress-ATT-Google-USB-Apple-Amazon.pdf

Beyond The Horizon
Mega Edition: Judge Hippler's Ruling On The Bryan Kohberger Digital Warrants (Part 3-4) (12/8/25)

Beyond The Horizon

Play Episode Listen Later Dec 8, 2025 27:22 Transcription Available


In Ada County Case No. CR01-24-31665, Defendant Bryan Kohberger filed motions to suppress evidence obtained through search warrants directed at AT&T, Google, USB devices, Apple, and Amazon. The defense argued that these warrants were invalid, alleging they were based on information gathered through unconstitutional methods, including the use of Investigative Genetic Genealogy (IGG), and that the affidavits supporting the warrants contained intentional or reckless omissions of material facts. They contended that the evidence obtained from these warrants violated Kohberger's Fourth Amendment rights and should therefore be excluded from trial.However, the court denied these suppression motions, ruling that the search warrants were lawfully issued and executed. The judge found that the affidavits provided sufficient probable cause and that the methods employed, including the use of IGG, did not violate constitutional protections. Additionally, the court determined that there was no evidence of intentional or reckless falsehoods or omissions in the affidavits that would warrant a Franks hearing. As a result, the evidence obtained from AT&T, Google, USB devices, Apple, and Amazon remains admissible in the proceedings against Kohbergerto contact me:bobbycapucci@protonmail.comsource:021925-Order-Defedants-Motions-Suppress-ATT-Google-USB-Apple-Amazon.pdf

The Moscow Murders and More
Mega Edition: Judge Hippler's Ruling On The Bryan Kohberger Digital Warrants (Part 5-6) (12/7/25)

The Moscow Murders and More

Play Episode Listen Later Dec 7, 2025 28:43 Transcription Available


In Ada County Case No. CR01-24-31665, Defendant Bryan Kohberger filed motions to suppress evidence obtained through search warrants directed at AT&T, Google, USB devices, Apple, and Amazon. The defense argued that these warrants were invalid, alleging they were based on information gathered through unconstitutional methods, including the use of Investigative Genetic Genealogy (IGG), and that the affidavits supporting the warrants contained intentional or reckless omissions of material facts. They contended that the evidence obtained from these warrants violated Kohberger's Fourth Amendment rights and should therefore be excluded from trial.However, the court denied these suppression motions, ruling that the search warrants were lawfully issued and executed. The judge found that the affidavits provided sufficient probable cause and that the methods employed, including the use of IGG, did not violate constitutional protections. Additionally, the court determined that there was no evidence of intentional or reckless falsehoods or omissions in the affidavits that would warrant a Franks hearing. As a result, the evidence obtained from AT&T, Google, USB devices, Apple, and Amazon remains admissible in the proceedings against Kohbergerto contact me:bobbycapucci@protonmail.comsource:021925-Order-Defedants-Motions-Suppress-ATT-Google-USB-Apple-Amazon.pdfBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Mega Edition: Judge Hippler's Ruling On The Bryan Kohberger Digital Warrants (Part 3-4) (12/7/25)

The Moscow Murders and More

Play Episode Listen Later Dec 7, 2025 27:22 Transcription Available


In Ada County Case No. CR01-24-31665, Defendant Bryan Kohberger filed motions to suppress evidence obtained through search warrants directed at AT&T, Google, USB devices, Apple, and Amazon. The defense argued that these warrants were invalid, alleging they were based on information gathered through unconstitutional methods, including the use of Investigative Genetic Genealogy (IGG), and that the affidavits supporting the warrants contained intentional or reckless omissions of material facts. They contended that the evidence obtained from these warrants violated Kohberger's Fourth Amendment rights and should therefore be excluded from trial.However, the court denied these suppression motions, ruling that the search warrants were lawfully issued and executed. The judge found that the affidavits provided sufficient probable cause and that the methods employed, including the use of IGG, did not violate constitutional protections. Additionally, the court determined that there was no evidence of intentional or reckless falsehoods or omissions in the affidavits that would warrant a Franks hearing. As a result, the evidence obtained from AT&T, Google, USB devices, Apple, and Amazon remains admissible in the proceedings against Kohbergerto contact me:bobbycapucci@protonmail.comsource:021925-Order-Defedants-Motions-Suppress-ATT-Google-USB-Apple-Amazon.pdfBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Mega Edition: Judge Hippler's Ruling On The Bryan Kohberger Digital Warrants (Part 1-2) (12/7/25)

The Moscow Murders and More

Play Episode Listen Later Dec 7, 2025 27:39 Transcription Available


In Ada County Case No. CR01-24-31665, Defendant Bryan Kohberger filed motions to suppress evidence obtained through search warrants directed at AT&T, Google, USB devices, Apple, and Amazon. The defense argued that these warrants were invalid, alleging they were based on information gathered through unconstitutional methods, including the use of Investigative Genetic Genealogy (IGG), and that the affidavits supporting the warrants contained intentional or reckless omissions of material facts. They contended that the evidence obtained from these warrants violated Kohberger's Fourth Amendment rights and should therefore be excluded from trial.However, the court denied these suppression motions, ruling that the search warrants were lawfully issued and executed. The judge found that the affidavits provided sufficient probable cause and that the methods employed, including the use of IGG, did not violate constitutional protections. Additionally, the court determined that there was no evidence of intentional or reckless falsehoods or omissions in the affidavits that would warrant a Franks hearing. As a result, the evidence obtained from AT&T, Google, USB devices, Apple, and Amazon remains admissible in the proceedings against Kohbergerto contact me:bobbycapucci@protonmail.comsource:021925-Order-Defedants-Motions-Suppress-ATT-Google-USB-Apple-Amazon.pdfBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

Wellness with Ella
Christmas Menus, Intolerance Tests and the Wellness Trends to Ignore

Wellness with Ella

Play Episode Listen Later Dec 4, 2025 36:41


In this Extra Scoop we're tackling your brilliant listener questions, from the confusion around food intolerance tests to what to cook for a summer Christmas lunch. We break down why IgG tests aren't reliable, how to get a proper diagnosis and why unnecessary restriction can do more harm than good. Rhi shares her clinical insight into navigating misinformation online, from the rise of the AIP diet to the red flags around unregulated “women's health practitioners.” We also answer your questions on omega-3 supplements, skincare ingredients like BHT and phenoxyethanol, and whether lots of small meals or three bigger ones best support digestion and sleep. Plus, we share your latest dark chocolate recommendations and talk through what a Deliciously Ella–style summer Christmas menu might look like. It's a practical, myth-busting episode designed to bring a bit of clarity, calm and common sense to the world of everyday wellness. Recommendations: The best dark chocolates (so far!): Sainsbury's Taste the Difference Madagascan 80%, M&S 75%, Tesco 85%, Divine 85%, Hu Kitchen, Ombar 80% Ella's book event: https://www.bookbaruk.com/event-details/meet-ella-mills-exclusive-pre-publication-signing-and-meet-greet Learn more about your ad choices. Visit podcastchoices.com/adchoices

DNA: ID
Opal Weil Part 1 of 2

DNA: ID

Play Episode Listen Later Nov 24, 2025 64:08


Episode 166 Opal Weil Part 1 of 2    In January 1987, 82 year old Opal Weil was slain in her St. Petersburg, FL home. The crime scene reflected a burglary, with Opal's wedding ring pulled off her finger.  Within a week, it happened again. Octogenarian Eleanor Swift's home, just 6 miles from Opal's, was burgled, she was killed, and her wedding ring taken.  A third victim in the same month survived, but remembered nothing.  The cases, quickly connected in the eyes of the investigators, went cold, despite a large number of suspects being considered.  Hairs found at Opal's crime scene, distinct from her own, would prove to be the key to an IGG analysis, and a suspect was finally identified and arrested for her murder in 2023.  But that is not the end of the story.      To listen to every episode of DNA: ID ad-free and get other benefits, simply  visit our channel page on Apple Podcasts to get started with an AbJack Insider subscription. Of course, you can also support DNA: ID with a Patreon subscription. Follow us on social media;  find all of our social media links in one spot at our Linktree:  linktr.ee/dnaidpodcast

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 13)

Beyond The Horizon

Play Episode Listen Later Nov 21, 2025 14:22 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 12)

Beyond The Horizon

Play Episode Listen Later Nov 21, 2025 12:49 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 11)

Beyond The Horizon

Play Episode Listen Later Nov 21, 2025 14:06


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 10)

Beyond The Horizon

Play Episode Listen Later Nov 20, 2025 15:05


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 9)

Beyond The Horizon

Play Episode Listen Later Nov 20, 2025 17:27 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 8)

Beyond The Horizon

Play Episode Listen Later Nov 20, 2025 13:53 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 7)

Beyond The Horizon

Play Episode Listen Later Nov 20, 2025 14:30 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 5)

Beyond The Horizon

Play Episode Listen Later Nov 19, 2025 11:15 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 6)

Beyond The Horizon

Play Episode Listen Later Nov 19, 2025 12:00 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 4)

Beyond The Horizon

Play Episode Listen Later Nov 19, 2025 12:22 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 2)

Beyond The Horizon

Play Episode Listen Later Nov 19, 2025 11:39 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 3)

Beyond The Horizon

Play Episode Listen Later Nov 19, 2025 10:55 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

Beyond The Horizon
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 1)

Beyond The Horizon

Play Episode Listen Later Nov 18, 2025 12:19 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.ecl

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 14)

The Moscow Murders and More

Play Episode Listen Later Nov 18, 2025 13:44 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 12)

The Moscow Murders and More

Play Episode Listen Later Nov 17, 2025 12:49 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 13)

The Moscow Murders and More

Play Episode Listen Later Nov 17, 2025 14:22 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 11)

The Moscow Murders and More

Play Episode Listen Later Nov 17, 2025 14:06 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 10)

The Moscow Murders and More

Play Episode Listen Later Nov 17, 2025 15:05 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 6)

The Moscow Murders and More

Play Episode Listen Later Nov 16, 2025 12:00 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 9)

The Moscow Murders and More

Play Episode Listen Later Nov 16, 2025 17:27 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 8)

The Moscow Murders and More

Play Episode Listen Later Nov 16, 2025 13:53 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 7)

The Moscow Murders and More

Play Episode Listen Later Nov 16, 2025 14:30 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 5)

The Moscow Murders and More

Play Episode Listen Later Nov 15, 2025 11:15 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 4)

The Moscow Murders and More

Play Episode Listen Later Nov 15, 2025 12:22 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 3)

The Moscow Murders and More

Play Episode Listen Later Nov 15, 2025 10:55 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 2)

The Moscow Murders and More

Play Episode Listen Later Nov 15, 2025 11:39 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

The Moscow Murders and More
Murder In Moscow: The IGG Closed Hearing Transcripts (Part 1)

The Moscow Murders and More

Play Episode Listen Later Nov 14, 2025 12:19 Transcription Available


On January 23, 2025, a closed hearing was held in the case of State of Idaho v. Bryan C. Kohberger before Judge Steven Hippler. The primary focus was the defense's motion to suppress evidence obtained through Investigative Genetic Genealogy (IGG), which they argued violated Kohberger's Fourth Amendment rights. Detective Brett Payne testified that the IGG lead was treated as a tip, with further independent investigation conducted to substantiate its validity. Defense expert Dr. Leah Larkin suggested potential violations of FBI policy and genealogy database terms of service during the IGG process. However, Judge Hippler expressed skepticism regarding the defense's claims, noting the lack of a reasonable expectation of privacy for DNA left at a crime scene.Following the hearing, Judge Hippler ordered the release of a redacted transcript, balancing public interest with privacy concerns. Redactions included the names of surviving roommates and distant relatives identified through IGG. The unsealed portions provide insight into the investigative methods used and the defense's challenges to the evidence's admissibility. This development underscores the ongoing legal debates surrounding the use of IGG in criminal investigations and its implications for privacy and constitutional rights.to contact me:bobbycapucci@protonmail.comsource:KB-25-01-23-Hearing-Redacted.eclBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-moscow-murders-and-more--5852883/support.

DNA: ID
The Denver Four Part 1 of 2

DNA: ID

Play Episode Listen Later Nov 10, 2025 54:11


Episode 164 The Denver Four Part 1 of 2   Four women were murdered in the Denver, CO area, three in 1980 and one in 1978, in crimes that remained unsolved – and unconnected – for decades.  The victims had nothing in common, the circumstances varied widely.  But modern DNA testing technology provided investigators with some very surprising information – and IGG tied it all together.  They were looking for one man for all four murders – and those were not the sum total of his heinous crimes.  Today's episode is about one of the more depraved killers identified by IGG, one you've likely never heard of.  To listen to every episode of DNA: ID ad-free and get other benefits, simply  visit our channel page on Apple Podcasts to get started with an AbJack Insider subscription. Of course, you can also support DNA: ID with a Patreon subscription. Follow us on social media;  find all of our social media links in one spot at our Linktree:  linktr.ee/dnaidpodcast

The Last American Vagabond
Jan 6 Pipe Bomber, Conservatives Turn On Trump & #TwoPartyIllusion Has Never Been More Vulnerable

The Last American Vagabond

Play Episode Listen Later Nov 9, 2025 207:58 Transcription Available


Welcome to The Daily Wrap Up, an in-depth investigatory show dedicated to bringing you the most relevant independent news, as we see it, from the last 24 hours (11/9/25). As always, take the information discussed in the video below and research it for yourself, and come to your own conclusions. Anyone telling you what the truth is, or claiming they have the answer, is likely leading you astray, for one reason or another. Stay Vigilant. !function(r,u,m,b,l,e){r._Rumble=b,r[b]||(r[b]=function(){(r[b]._=r[b]._||[]).push(arguments);if(r[b]._.length==1){l=u.createElement(m),e=u.getElementsByTagName(m)[0],l.async=1,l.src="https://rumble.com/embedJS/u2q643"+(arguments[1].video?'.'+arguments[1].video:'')+"/?url="+encodeURIComponent(location.href)+"&args="+encodeURIComponent(JSON.stringify([].slice.apply(arguments))),e.parentNode.insertBefore(l,e)}})}(window, document, "script", "Rumble");   Rumble("play", {"video":"v6za9zu","div":"rumble_v6za9zu"}); Video Source Links (In Chronological Order): (21) Zachary Foster on X: "Only 1 of 102 antisemitism investigations at US universities over the past 2 years were unrelated to criticism of Israel, according to publicly available data reviewed by @AAUP & @MESA_1966. Mainstream media has manufactured a gigantic antisemitism hoax. https://t.co/CGqxELfB0U https://t.co/Q5VEujbfj0" / X (21) Peter A. McCullough, MD, MPH® on X: "BREAKING: Peer-Reviewed Study Finds COVID-19 "Vaccines" Linked to 63 Serious Brain and Spinal Cord Adverse Events 63 CDC/FDA safety thresholds breached as mRNA-LNP-Spike disrupts the blood–brain barrier, increasing risks of meningitis, encephalitis, prion disease, brain https://t.co/EvEaT82nZQ" / X View of COVID-19 mRNA vaccination: implications for the central nervous system Frontiers | A calibration of nucleic acid (PCR) by antibody (IgG) tests in Germany: the course of SARS-CoV-2 infections estimated You Have Every Reason To Question EVERYTHING You're Told About Variants, Vaccines, Masks & PCR Tests PCR Archives - The Last American Vagabond Faith in Quick Test Leads to Epidemic That Wasn't - The New York Times The PCR Illusion & 'The Epidemic That Wasn't' Pathologist Arne Burkhardt Final Interview - Revealing the Grave Dangers of mRNA Vaccines Pfizer and BioNTech's COMIRNATY® Receives U.S. FDA Approval for Adults 65 and Older and Individuals Ages 5 through 64 at Increased Risk for Severe COVID-19 | Pfizer (21) The Last American Vagabond on X: "What happened is they lied to you. As they all do. The real question is whether conservatives will still stand by them despite repeated lies and sell outs." / X (21) X22 Report on X: "Here is a video of the Ozempic executive fainting in front of Trump. Do you see why they are called the fake news? https://t.co/3T5DQ7opnI" / X (21) The Last American Vagabond on X: "So apparently Ozempic, Bill Gates' fake food, and transgenic edible vaccines (and even new COVID shots) are "MAHA"... or is that just what the blind followers say? Speak up conservatives, show the nation that you are not what the #TwoPartyIllusion pretends you are. #Winning" / X Trump Admin Leans Into Self-Amplifying mRNA (SamRNA) Under Guise Of Ending mRNA & RNA In Food New Tab (21) swordofthejedi❤️‍

More Than Medicine
MTM - Interview with Ursula Conway..Arizona Chapter CHD

More Than Medicine

Play Episode Listen Later Nov 8, 2025 21:15 Transcription Available


Send us a textA quiet ranch near the Arizona border, a stack of mandates, and a pharmacist looking for an exemption—that's the unlikely spark behind covidindex.science, a volunteer-built library now holding more than 2,100 entries of COVID studies, interviews, and podcasts. We sit with Ursula Conway to unpack how a Word document became a public resource adopted by Children's Health Defense and designed for anyone who needs clear, searchable evidence without the noise.We walk through how clinicians used CDC myocarditis statements to support medical exemptions for young men, and how families facing cancer searched the index to explore concerns around IgG antibodies, P53 tumor suppression, and ongoing boosters. If you've ever tried to remember a term you heard while driving—only to lose the thread—the index's simple and advanced search makes it easy to find sources by topic, mechanism, or expert, from cancer risk signals to immune responses. Attorneys gain quick access to excerpts for filings, while researchers and patients can follow curated trails that challenge safe-and-effective talking points with primary sources.Ursula shares why CHD's team provides scientific oversight while volunteers do the heavy lifting of curation, and how this citizen-led model resists censorship by distributing the work across many hands. We also zoom out to CHD's wider mission across research, legislation, and litigation on vaccines, wireless exposure, and environmental health, offering a wider lens on informed consent and medical freedom. Whether you're a doctor, lawyer, parent, or curious listener, you'll leave with a practical way to engage: search, verify, share—then consider contributing your own findings to strengthen the commons.Explore the library at covidindex.science, try the advanced search for your topic, and tell us what you discover. If it helps, subscribe, leave a review, and share this episode with someone who needs better sources today.Support the showhttps://www.jacksonfamilyministry.comhttps://bobslone.com/home/podcast-production/

DNA: ID
Doe ID: Roberta Mumma

DNA: ID

Play Episode Listen Later Nov 3, 2025 21:10


Episode 163 Doe ID: Roberta Mumma   In 1984, the decomposed remains of a woman wrapped in plastic were found in remote Wizard Wells, Jack County, TX.  Experts posited that she was a young white woman, but without any identification, no fingerprints, and no corresponding missing persons reports, she could not be identified. Fast forward nearly 40 years – when IGG would be used on her bones to identify her as Roberta Mumma.  Roberta hailed from the Lancaster, PA area and was believed to have died around age 25.  Her death is considered a homicide, and the Jack County authorities and the Texas Rangers are seeking information about her case.   To listen to every episode of DNA: ID ad-free and get other benefits, simply  visit our channel page on Apple Podcasts to get started with an AbJack Insider subscription. Of course, you can also support DNA: ID with a Patreon subscription. Follow us on social media;  find all of our social media links in one spot at our Linktree:  linktr.ee/dnaidpodcast

Paige Talks Wellness
240: Are You Really Sensitive to That Food? // Food Sensitivities, Intolerances, & Allergies

Paige Talks Wellness

Play Episode Listen Later Oct 29, 2025 25:35


If you've ever felt like your list of "off-limits" foods just keeps getting longer, this episode is for you. I'm breaking down the truth about food sensitivities - what they actually are, how they're different from allergies and intolerances, and why your symptoms might show up differently than your friend's. Because food isn't the enemy. Once you support your gut, calm your immune system, and rebuild tolerance, your body can go back to doing what it's designed to do: thrive with variety. In this episode, I'll cover: The real difference between food allergies, sensitivities, and intolerances - and why mixing them up leads to confusion Why food sensitivity symptoms can show up days after eating and look totally different from person to person The truth about IgG food sensitivity tests and what those "reactive" foods actually mean How gut dysfunction, stress, and environmental toxins set the stage for reactivity A step-by-step guide to doing an elimination and reintroduction process safely and effectively Why cutting out more foods isn't the answer - and how to rebuild tolerance so you can enjoy eating again --- Show Notes: Sign up for a 1:1 Discovery Call Join the Imperfectly Paige Wellness Community Join the Compass Method DIY Program Jump inside my Rock the Bloat Minicourse Get my Core-Gi Workout Program with the exclusive listener discount! Join my Brain Rewiring Masterclass You can learn more about me by following on IG @imperfectlypaigewellness or by checking out my blog, freebies, and offers on my website: https://imperfectlypaigewellness.com Please share with #PaigeTalksWellness to help get the word out about the show - and join the Imperfect Health Fam over on Facebook.

DNA: ID
Leslie Preer Part 1 of 2

DNA: ID

Play Episode Listen Later Oct 27, 2025 68:23


Episode 162 Leslie Preer Part 1 of 2 Upscale Chevy Chase, MD does not see a lot of violent crime. But that changed in 2001, when loving wife and mom Leslie Preer was beaten to death in her own home in a shocking crime. Investigators could find no motive for the murder, but certain aspects of the crime scene directed investigators' attention to Leslie's husband as the prime suspect. After all, it was very unlikely that a stranger had broken into the house, killed Leslie, and attempted a clean-up. But they could not pin the crime on Carl Preer, and the case stalled. Not until the Montgomery County PD cold case unit embraced IGG did they find a name of a suspect – one who had been under their noses the whole time. This episode is sponsored by Uncommon Goods; your source for unique and special products and gifts. Listeners of DNA ID can save 15% off their next order when they use our special show link To listen to every episode of DNA: ID ad-free and get other benefits, simply visit our channel page on Apple Podcasts to get started with an AbJack Insider subscription. Of course, you can also support DNA: ID with a Patreon subscription. Follow us on social media; find all of our social media links in one spot at our Linktree: linktr.ee/dnaidpodcast

DNA: ID
Doe ID: Wynona Michele

DNA: ID

Play Episode Listen Later Oct 20, 2025 24:34


Episode 161 Doe ID:  Wynona Michele   In 1990, Madison County IL authorities recovered the remains of a nude young woman in a soybean field. She had some articles of clothing and jewelry with her, but no identification.  Investigators could not identify her, and she was buried in a church cemetery with a headstone that called her Jane Doe.  But they had the foresight to retain some physical evidence, and with the advent of IGG, were able to use that evidence to locate living relatives of Jane Doe.  She was Wynona Nadine Michel – but her identity is just part of the mystery.  She is now the subject of an active homicide investigation. Who killed Wendy Michel?   To listen to every episode of DNA: ID ad-free and get other benefits, simply  visit our channel page on Apple Podcasts to get started with an AbJack Insider subscription. Of course, you can also support DNA: ID with a Patreon subscription. Follow us on social media;  find all of our social media links in one spot at our Linktree:  linktr.ee/dnaidpodcast

Vanessa G Fitcast
Ep. 246 What I Learned From My MRT Results (and Why Most Food Sensitivity Tests Get It Wrong)

Vanessa G Fitcast

Play Episode Listen Later Oct 20, 2025 32:05


What if your “food sensitivities” weren't really the problem—but just the message your body's been trying to send you? In this episode, we unpack what most food sensitivity tests get wrong and why the MRT (Mediator Release Test) is one of the few tools that can actually reveal what's really inflaming your body. In today's episode, we'll share my personal journey of years of bloating, fatigue, and restriction—before finally discovering how MRT testing offered real answers instead of endless guesswork. You'll learn how popular IgG tests often mislead people into cutting out 20+ foods unnecessarily, and how MRT goes deeper by measuring your actual inflammatory response—not just antibody exposure. We'll break down what the results actually mean, why some “healthy” foods might be triggering your system, and how to use that information to heal, not just restrict. This episode also explores the root causes behind sensitivities—like low stomach acid, leaky gut, chronic stress, and dysbiosis—and how to rebuild tolerance instead of living in fear of food. Through my own experience of reintroducing foods and repairing gut function, I show how MRT can shift you from feeling reactive and confused to calm and confident in your body again. If you've tried every elimination diet, still feel inflamed, and are tired of playing food detective, this conversation will help you see sensitivities for what they really are: signals, not sentences. By the end, you'll understand why healing the terrain, not just removing the foods, is the key to lasting relief—and how using data the right way can bring back freedom, flexibility, and trust in your body. Time Stamps: (1:42) Country T-Swift Fan (2:47) Being An Optimizer (4:57) Food Sensitive/MRT (9:27) Overactive Immune System (11:57) Note on MRT Test (16:52) What Foods To Eat When (20:22) Lowering Inflammation---------------------Find Out More Information on Vital Spark Coaching---------------------Follow @vanessagfitness on Instagram for daily fitness tips & motivation. ---------------------Download Our FREE Metabolism-Boosting Workout Program---------------------Join the Women's Metabolism Secrets Facebook Community for 25+ videos teaching you how to start losing fat without hating your life!---------------------Click here to send me a message on Facebook and we'll see how I can help or what best free resources I can share!---------------------Interested in 1-on-1 Coaching with my team of Metabolism & Hormone Experts? Apply Here!---------------------Check out our Youtube Channel!---------------------Enjoyed the podcast? Let us know what you think and leave a 5⭐️ rating and review on iTunes!

DNA: ID
Robin Lawrence

DNA: ID

Play Episode Listen Later Oct 13, 2025 96:32


Episode 160 Robin Lawrence   In this shocking and heart-wrenching 1994 case, a young Northern Virginia mother is killed in her own in a vicious crime that shocked even seasoned members of law enforcement. Not only was the brutality breathtaking, but Robin's 2 year old daughter was left with her mother's corpse for two whole days. This case confounded Fairfax County police, because Robin had no enemies, yet the crime of passion clearly targeted her.  A prime suspect emerged whom police were convinced did it, only to be disappointed by DNA results.  It's not an overstatement to say that were it not for IGG, the murder of Robin Lawrence would never have been solved.  Because the identity of the killer, and his reasons for slaying Robin, were simply impossible to believe. To listen to every episode of DNA: ID ad-free and get other benefits, simply  visit our channel page on Apple Podcasts to get started with an AbJack Insider subscription. Of course, you can also support DNA: ID with a Patreon subscription. Follow us on social media;  find all of our social media links in one spot at our Linktree:  linktr.ee/dnaidpodcast