Podcasts about Diet

Your Hormones Are Killing You: Oxytocin, FSH, and the Anti-Aging Protocol Most Doctors Ignore Your hormones are running your love life, your intuition, your longevity, and your brain, and most doctors are getting it completely wrong. Host Dave Asprey sits down with triple board-certified OBGYN Dr. Anna Cabeca to break down the clinical science of oxytocin, female pleasure, hormonal optimization, and why fixing your hormones can make your 70s the best decade of your marriage. Dr. Anna Cabeca is a triple board-certified OBGYN and fellow of gynecology and obstetrics, integrative medicine, and anti-aging and regenerative medicine, with additional board certifications in functional medicine, sexual health, and bioidentical hormone replacement therapy. She is the bestselling author of The Hormone Fix, Keto-Green 16, and MenuPause, and has spent decades researching the clinical intersection of oxytocin, cortisol, estrogen, and progesterone on women's hormonal health, metabolism, and longevity. Her work on keto-green nutrition, vaginal and bladder microbiome health, and bioidentical hormone replacement has made her one of the most credentialed and clinically experienced voices in women's functional medicine practicing today. Dave and Dr. Anna break down the real pharmacology of oxytocin, including its role in muscle regeneration, cortisol suppression, mitochondrial signaling, and vagal tone optimization. They expose the toxic ingredients hiding in mainstream lubricants and vaginal hormone creams, including aspartame, parabens, and petroleum derivatives, and explain why the vaginal microbiome is a frontline organ for women's metabolism and anti-aging. They get into the neuroscience of orgasm, pineal gland activation, endogenous DMT release, and the neurochemical cascade behind peak altered states. Dr. Anna also breaks down the Women's Health Initiative disaster, the FDA's recent reversal on bioidentical hormone replacement, and why FSH is a critical and widely overlooked longevity biomarker. High post-menopausal FSH drives neuroinflammation, accelerates bone loss, and degrades brain optimization outcomes, and most physicians are not testing for it. This is essential listening for anyone serious about biohacking, longevity, anti-aging, functional medicine, human performance, brain optimization, and taking full ownership of their biology. You'll Learn: Why oxytocin functions as a regenerative hormone that rebuilds muscle, suppresses cortisol, and supports mitochondria signaling What toxic chemicals are hiding in standard lubricants and vaginal hormone creams and what to use instead How orgasm activates the pineal gland and triggers endogenous DMT release and altered neurological states Why female intuition may be directly linked to mitochondrial density concentrated in the ovaries How elevated FSH drives neuroinflammation, bone loss, and accelerated brain aging in post-menopausal women Why the FDA reversed 30 years of flawed guidance on bioidentical hormone replacement therapy How four days of sensory deprivation supercharges melatonin, oxytocin, and endogenous DMT production Why oxytocin combined with ketamine is being used clinically to break trauma patterns and rewire neural pathways How polyphenols, CoQ10, carnitine, and vagal tone training protect cardiovascular health and support longevity Why polypharma accelerates decline and what functional medicine does differently Thank you to our sponsors! - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - Gatlan | Book your free consultation at www.gatlan.com/DAVE - Redmond Real - Leaf Toothpaste | Go to https://redmond.com/asprey and use code ASPREY for 15% off your first order. - Neuronic | Go to www.neuronic.online Code DAVE for $100 off Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Anna Cabeca, The Girlfriend Doctor, oxytocin, bioidentical hormone replacement, FSH, follicle-stimulating hormone, vaginal microbiome, Velve lubricant, Julva, Mighty Maca, cortisol suppression, pineal gland, DMT, neuroinflammation, broken heart syndrome, NT-proBNP, vagal tone, dark retreat, orgasmic meditation, Women's Health Initiative, perimenopause, postmenopause, yoni massage, oxytocin nasal spray, cabergoline, prolactin, Pitocin, CoQ10, carnitine, Arterosil, polypharma, keto-green, The Hormone Fix Resources: • Get An Exclusive Offer On Dr. Anna's Products At: dranna.com/tribe • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:37 – What Is Oxytocin? 07:38 – Clean Lube Launch 09:11 – Toxic Lube Ingredients 17:08 – Oxytocin Prescribing 18:58 – FDA Reverses HRT Warning 26:50 – Dark Retreat & DMT 32:15 – Orgasmic Meditation 42:06 – Female Intuition 46:21 – Broken Heart Syndrome 51:15 – FSH & Hormone Monitoring See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Do you wake up with knee pain and knee stiffness every morning? Discover the hidden cause of morning knee pain, simple knee pain exercises you can do in bed, and natural ways to support healthy knee joints. 0:00 Morning knee stiffness relief 0:20 Knee inflammation explained 2:24 Knee pain exercises 4:05 Arthritis in the knee joints5:35 How to stop knee pain5:46 Turmeric for arthritis6:14 Vitamin D for healthy knee joints 7:27 Diet and knee pain9:11 Quad strength and knee pain9:27 Sit-to-stand exercises10:17 Backward walking for knee pain11:11 Knee pain relief tips

Dr. Georgia Ede is a Harvard-trained psychiatrist and author specializing in nutrition and ketogenic diets for mental health.Show partners:LMNT - Claim your free LMNT Sample Pack with any purchase by using this linkQuicksilver Scientific - Save 15% off your first order by using the code "jesse15" at checkoutShow notes:jessechappus.com/711

Mens Room Top 10

WWE Tag-Team Champion Austin Theory joins the boys to discuss his strange relationship with Vince McMahon, beating John Cena at WrestleMania 39, his beef with Roman Reigns

High cholesterol has been treated as the main cause of heart disease for decades. But over the years, I've changed my mind. Today, I believe cholesterol is only part of the story, and that inflammation, insulin resistance, and metabolic health are often the real drivers of cardiovascular disease. In this encore episode, I'm revisiting one of my most talked-about Office Hours conversations to share how my thinking has evolved and why understanding the root cause of heart disease can completely change the way you approach prevention. In today's episode, I discuss: Why cholesterol alone is a poor predictor of heart disease—and the biomarkers I believe matter even more, including ApoB, lipoprotein(a), inflammation, and insulin resistance The surprising role sugar, refined carbohydrates, and metabolic dysfunction play in driving cardiovascular disease Why two people with the same cholesterol can have dramatically different heart disease risk—and how a personalized approach changes the conversation The nutrition, lifestyle, and testing strategies I use to help reduce inflammation, improve metabolic health, and lower cardiovascular risk at its source Heart disease isn't simply a cholesterol problem—it's often a metabolic and inflammatory problem. When you understand what's really driving your risk, you can stop chasing a single number and start addressing the underlying biology that supports lifelong cardiovascular health. Track your metabolic and cardiovascular health biomarkers: functionhealth.com/mark for 160+ lab tests at just $365/year. Use code MARK2026 for $50 off. Have a question you'd love answered on Office Hours? Submit it here' (0:00) The cholesterol and heart disease paradox; introduction and overview of cholesterol, inflammation, and metabolic health (1:11) Sponsor: Function Health (1:41) Traditional views vs. new science on cholesterol, inflammation, and heart disease (4:52) Inflammation and sugar as key factors in heart disease (8:41) Advanced markers: ApoB, lipoprotein fractionation, and comprehensive testing (13:57) Causes of inflammation and holistic heart disease prevention (19:35) Metabolic health risks, new technologies, and personalized interventions (22:35) Diet, exercise, lifestyle, and supplements for heart and metabolic health (25:03) Understanding heart disease beyond cholesterol (25:37) Sponsor: Brain Shaping Academy (26:33) Community engagement, sharing, and final thoughts (28:07) Sponsor acknowledgments and closing remarks

You already know something has changed - the energy crashes, the slow recovery, the brain fog that wasn't there ten years ago. Most people assume that's just aging. But it's NOT. Nobel Prize-winning research has identified a single molecule that controls how fast your body breaks down, and more importantly, exactly why yours is being destroyed faster than it's being rebuilt. The fix isn't complicated, but the order you do it in matters. In this video, Dave breaks down what this molecule is, why your body is actively working against it, and the exact protocol (diet, fasting, exercise, and supplementation) to restore it before the gap gets any wider.Thank you to our sponsors!Gatlan | Book your free consultation at www.gatlan.com/DAVEViome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:0:00 – The Longevity Switch0:47 – Why Mitochondria Matter2:28 – What Mitophagy Is2:46 – How Mitophagy Works4:18 – What Shuts It Off8:54 – The Damage Compounds9:22 – How to Turn It Back On10:31 – Signal 1: Fasting11:48 – Signal 2: Exercise (REHIT)12:30 – Signal 3: Cold Exposure13:22 – Signal 4: NAD+14:29 – Signal 5: Urolithin A and SpermidineConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Anonymous: I'm a 46-year-old female (163 cm, 81.5 kg) recent leg swelling, especially left leg with significant fluid from the knee into the foot. Blood clot + kidney issues are ruled out, but ALT is at 209 U/L (10–45). In January a doctor diagnosed lipedema stage 1–2 in legs and arms, left leg was not swollen like this then. My legs may swell slightly in heat, but not in Denmark. EquiLife labs are not possible here. I look 6–7 mths pregnant all day, not hard, no gas. Difficulty losing weight detoxes no longer effective. Diet smoothie (berries, kale, DNS, chia,psyllium,creatine,collagen), lunch cauliflower rice, chicken, arugula, dinner potatoes/meat/veg, pasta 1–2xweek, water + 1–2 drinks/week.I'm peri started bioidentical hormones in January hot flashes gone, mood improved. If I was your wife?      Sarah: Hello! I had a question about 'fascia blasting'. Despite doing everything you recommend for cellulite for years now, I still have it on my legs. For a few weeks ive been trying fascia blasting with  device and my legs have improved so much. They feel firmer, less painful to touch, and cellulite has improved. I cant believe the results. Curious what your thoughts are on this. Is it 'dangerous' (as some comments online say), is there any science behind it? My skin does bruise alot after I do it, but this doesnt bother me as the results I've been seeing are great. Always trust your imput, thanks so much!!       Trent: Hi, I have never had trouble sleeping up until around 6 weeks ago. When it first started, I started waking up in between 3-4am, having very deep vivid dreams every night. Most of the times I could get back to sleep not long after but sometimes if I wake at around 5am I stay awake. My sleep time does vary a bit but I usually get around on average 6.5-7 hours a night, sometimes more and sometimes less. Previously I had never had any troubles sleeping and would never consistently wake up at these times. 2 things I know I need to limit or stop doing is taking my laptop into bed and limit my sugar intake. I do not feel stressed at the moment but I do have some big decision to make this year that are always on my mind.       Sarah: Hello! I've recently been hearing about chlorine neutralizer sprays that some parents use on children before or after swimming. From what I understand, many contain vitamin C or similar ingredients that are supposed to neutralize chlorine or chloramines on the skin and hair to help reduce irritation or exposure. I wanted to ask your opinion on them. Do you think these sprays are actually beneficial or safe for regular use on children? Are they helpful for kids with sensitive skin, eczema, or allergies, or is rinsing/showering after swimming usually enough? I've also seen some claims online about reducing chlorine absorption into the body, and I'm not sure how accurate that is. Are there better natural approaches for protecting skin before or after swimming in chlorine pools? Thanks!       Audrey: Hi Dr. Cabral, Is greenhouse grown lettuce as nutritious as non greenhouse grown? The package states not sprayed with any pesticides. I try to get my lettuce from my local farmers market but sometimes I cannot make it there. The greenhouse grown seems to be much fresher and better quality than regular store lettuce       Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3795 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Fish Oil Supplements And Alzheimer's-Related Decline A two-year randomized, double-blind, placebo-controlled trial led by researchers at USC tested whether 2,000 mg of DHA fish oil daily could slow Alzheimer's-related brain changes in 365 adults ages 55–80 who rarely consumed fish and had at least one Alzheimer's risk factor. Researchers confirmed the supplement reached the brain by measuring a roughly 17% increase in cerebrospinal fluid DHA after six months. Despite successfully increasing brain DHA levels, participants taking fish oil showed no significant improvements in memory, global cognitive function, or hippocampal volume compared to placebo after two years. Host Dave Asprey explains why raising a single biomarker doesn't always translate into better brain performance, why nutrition works differently inside a complete dietary pattern than as an isolated supplement, and what this study means for anyone relying on fish oil as an Alzheimer's prevention strategy. Sources: https://medicalxpress.com/news/2026-06-fish-oil-supplements-alzheimer-decline.pdf https://www.cnn.com/2026/06/18/health/omega-3-fish-oil-algae-supplement-wellness ~~ DASH Diet Showed the Strongest Link to Long-Term Brain Health Researchers from Harvard analyzed dietary data from 159,347 participants across three long-running U.S. health studies to examine how eating patterns influence cognitive aging. Participants completed dietary questionnaires every four years over several decades, allowing investigators to compare six healthy dietary patterns, including the DASH and Mediterranean diets. While all six were associated with better cognitive health later in life, adherence to the DASH diet produced the strongest association, with participants showing roughly a 40% lower risk of subjective cognitive decline and stronger performance on objective cognitive testing. The protective relationship was strongest when healthy eating habits began during midlife. Host Dave Asprey breaks down why blood sugar control, lower inflammation, and healthier blood vessels may be the real drivers behind long-term brain resilience, and why your dietary choices in your 40s and 50s may have an outsized impact on cognitive aging decades later. Sources: https://jamanetwork.com/journals/jamaneurology/article-abstract/2845466 https://www.health.harvard.edu/diet-and-nutrition/harvard-study-six-healthy-diets-linked-with-better-long-term-brain-health https://www.eurekalert.org/news-releases/1117225 ~~ Scientists Identified an Ancient Brain Circuit That Filters Distractions Johns Hopkins researchers discovered a small population of inhibitory neurons within an evolutionarily ancient brainstem region that appears to control selective attention by determining which sensory information deserves focus and which distractions should be ignored. Mice trained on visual attention tasks consistently ignored irrelevant stimuli until researchers temporarily silenced these neurons, causing even weak distractions to hijack their attention while leaving vision and movement otherwise unaffected. Similar brain circuits exist in birds, reptiles, and other vertebrates, suggesting this attentional filtering system evolved long before the modern human cortex. Host Dave Asprey explains why attention may depend on much older brain circuitry than previously believed, how this discovery could reshape our understanding of ADHD and autism, and why future therapies may target the brainstem instead of the prefrontal cortex. Sources: https://www.sciencedaily.com/releases/2026/06/260624025426.htm ~~ Nearly Half of Older Adults Improved With Age Instead of Declining A Yale-led study followed 11,340 adults age 65 and older for up to 12 years using repeated measurements of cognition and walking speed to better understand how aging changes over time. Rather than finding universal decline, researchers discovered that 45% of participants improved in either cognitive function, physical performance, or both. Nearly one-third experienced measurable cognitive improvements, while over one-quarter improved physically. Researchers also found that participants with more positive beliefs about aging were significantly more likely to improve, even after accounting for education, chronic illness, depression, and other health factors. Host Dave Asprey explores why expectations about aging may become biologically embedded, why decline is far less inevitable than conventional medicine often assumes, and how mindset may directly influence healthy longevity. Sources: https://www.sciencedaily.com/releases/2026/06/260620100428.htm ~~ Glyphosate May Be Contributing to Antibiotic-Resistant Superbugs Researchers publishing in Frontiers in Microbiology examined 102 bacterial strains collected from hospitals, agricultural land, and protected wetlands to investigate whether glyphosate exposure contributes to multidrug antibiotic resistance. Hospital bacteria demonstrated extensive resistance to both antibiotics and glyphosate, while even bacteria living inside protected nature reserves displayed measurable glyphosate resistance despite no direct herbicide application. Genetic analysis suggested resistant bacterial strains may move between agricultural environments and hospitals through shared waterways and sediments. The researchers argue pesticide safety testing should also evaluate whether chemicals encourage antibiotic resistance, one of the world's fastest-growing public health threats. Host Dave Asprey explains why environmental toxins may have unintended effects on the human microbiome, how herbicides could influence antimicrobial resistance beyond farming, and why environmental biology increasingly belongs in conversations about human health. Sources: https://www.sciencedaily.com/releases/2026/06/260620100434.htm https://www.openaccessgovernment.org/common-weedkiller-glyphosate-linked-to-rise-in-superbugs-scientists-warn/207515/ ~~ Butterflies That Barely Age Could Unlock New Longevity Pathways Researchers from the University of Bristol found that Heliconius butterflies live dramatically longer than closely related butterfly species while aging much more slowly. In one comparison, Heliconius hewitsoni survived up to 348 days, while a closely related species lived only 14 days. Unlike most butterflies, Heliconius feed on pollen throughout adulthood, providing amino acids that help preserve muscle function and physical performance with age. However, even when pollen was removed, these butterflies still significantly outlived their relatives, suggesting evolved genetic and metabolic mechanisms also contribute to their exceptional longevity. Host Dave Asprey explores why nature continues to provide unexpected models for slowing biological aging, what scientists hope to learn from species that naturally maintain function over time, and how comparative biology may uncover entirely new pathways for extending human healthspan. Sources: https://www.sciencedaily.com/releases/2026/06/260622014302.htm ~~ This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want mechanism-level insights into omega-3 supplementation and Alzheimer's prevention, nutrition strategies for preserving cognitive health, newly discovered brain circuits controlling attention, the surprising biology behind healthy aging, environmental drivers of antibiotic resistance, and what one remarkably long-lived butterfly can teach us about extending healthspan. Host Dave Asprey connects randomized clinical trials, large population studies, neuroscience discoveries, microbiology research, and evolutionary biology into practical frameworks for improving brain performance, resilience, and longevity. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: fish oil Alzheimer's study, DHA supplements memory, omega-3 brain health, DASH diet cognition, dementia prevention diet, cognitive decline nutrition, selective attention brainstem, focus neuroscience, ADHD brain research, positive aging beliefs, healthy aging study, cognitive improvement older adults, glyphosate antibiotic resistance, superbugs glyphosate, environmental toxins microbiome, butterfly longevity research, Heliconius aging, longevity science, biohacking news 2026, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today - Neuronic | Go to www.neuronic.online Code DAVE for $100 off - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:18 – Story #1 Fish Oil 02:31 – Story #2 DASH Diet 03:49 – Story #3 Brain Stem Attention Filter 05:59 – Story #4 Cognitive Decline Lies 08:24 – Story #5 Glyphosate 10:16 – Story #6 Butterfly Lifespan Research 12:16 – Biohacking Criticism Response See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Stop following diets and start building the skills that make healthy eating effortless. In this episode, I explain why nutrition shouldn't feel like a constant struggle, how consistency creates progress, and why mastering your eating habits is far more effective than chasing the latest diet. You'll also learn the difference between healthy eating and fat loss, plus a simple calorie hacking strategy that makes managing body fat more sustainable over the long term.If you're tired of dieting and ready to build nutrition habits that actually last, this video is for you.Be Fit. Live Free.- Matt

Vitamin K2 (MK-7) and Coronary Artery Calcification: Insights from a 2-Year Trial: Nutritionist Leyla Muedin discusses a two-year randomized clinical trial in JAMA Cardiology from Maastricht University Medical Center reporting that daily vitamin K2 (menaquinone-7, MK-7) at 360 mcg slowed progression of coronary artery calcification (CAC) in 180 patients with confirmed atherosclerotic cardiovascular disease and baseline CAC 50–400 Agatston units. Compared with placebo, consistent MK-7 use was associated with 29% lower CAC progression and 42% less arterial calcium mass progression, though CAC still increased in both groups; stenosis increases were numerically lower with MK-7 but not statistically significant. Leyla notes many participants were on statins and were smokers, highlighting that statins can raise CAC by stabilizing soft plaque via calcification. The trial suggests MK-7 may slow calcification in newer plaques, may improve arterial elasticity via matrix GLA protein activation, is inexpensive and safe, but clinical event reduction remains unproven; Leyla suggests considering MK-7 (possibly 360 mcg) with vitamin D, magnesium, and dietary measures.

Most energy drinks trade your long-term health for a short-term jolt. This episode breaks down a smarter approach to energy, one that builds mitochondria function, supports gut health, stabilizes mood, and helps you sleep better at night, all without the crash -Get 15% off your next order at: https://getmte.com/dave Host Dave Asprey sits down with Jeff Boyd, founder and chairman of MTE (More Than Energy), the caffeine-free energy drink built around adaptogens, nootropics, and prebiotics that delivers what Boyd calls "energy that loves you back." Before launching MTE, Jeff spent 15 years as President and co-owner of Luggage Free, scaling the company to operations in over 100 countries before selling it in 2019. He brings the operational discipline of a veteran entrepreneur and the personal conviction of someone who built the energy product he actually wanted to exist. Dave and Jeff get into the full science and strategy behind MTE's ingredient stack, including paraxanthine, ashwagandha, eleuthero, maca, GABA, theanine, and saffron, and why each one was chosen for its role in stress response, brain optimization, and sleep optimization. They also dig into the formulation challenges of building a clean-label supplement over a stimulant base, the real difference between caffeine and its downstream metabolite paraxanthine, and why this blend functions more like a foundational biohacking protocol than a beverage. You'll Learn: Why conventional energy drinks wreck your cortisol curve and what to do instead How paraxanthine delivers the benefits of caffeine without the jitters or sleep disruption The adaptogen trio (ashwagandha, eleuthero, and maca) and how they work together for stress response and human performance Why saffron is one of the most underrated nootropics for mood and brain optimization How gut health and the microbiome connect directly to your energy, metabolism, and longevity The mitochondria connection between willpower, physical performance, and entrepreneurial output How AI is reshaping small teams and what founders need to do right now to stay competitive Why the cleanest path to anti-aging and longevity starts with how you manage your energy across the day Thank you to our sponsors! - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - Gatlan | Book your free consultation at www.gatlan.com/DAVE - BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. - Danger Coffee | Grab yours at DangerCoffee.comand use code DAVEPOD at checkout for 15% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Jeff Boyd, MTE, More Than Energy, caffeine-free energy, paraxanthine, adaptogens, ashwagandha, eleuthero, maca, nootropics, saffron, GABA, theanine, prebiotics, gut health, stress response, cortisol management, sleep optimization, huckleberry acai, clean label formulation, stevia Reb A, energy drink alternative, paraxanthine vs caffeine, afternoon energy, Luggage Free, cycling endurance, long jump training, ADHD entrepreneurship, AI small teams, willpower mitochondria Resources: • Get 15% off your next order at: https://getmte.com/dave • Purchase Dr. Fotuhi's New Book The Invincible Brain: https://a.co/d/0iHCgPpL • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:42 – What Is MTE? 03:50 – Ingredients Deep Dive 09:49 – Flavors & Formulation 12:31 – Dave's Caffeine Origin 18:35 – Athletic Identity 22:38 – ADHD & Entrepreneurship 26:43 – AI & Future of Work 30:47 – Willpower & Mitochondria 35:34 – MTE Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How quickly can you improve your gut health? Can diet help lower your risk of dementia? And what should you know about food labels and healthy weight loss? In this special live Q&A, Prof Tim Spector, Prof Sarah Berry and Dr Federica Amati answer your biggest nutrition questions and share practical, evidence-based advice you can use today. Drawing on decades of research and data from hundreds of thousands of people, they explain how diet can influence the gut microbiome, brain health, hunger, energy levels and long-term health. They discuss dementia risk, healthy snacking, intermittent fasting, ultra-processed foods, plant diversity, breakfast, food labels and the latest science on weight loss. You'll learn how quickly the gut microbiome may respond to dietary change, why some foods keep you fuller for longer, how to build a healthier breakfast, and simple ways to make better food choices. The team also explain why small dietary changes can have lasting benefits. If your daily food choices influence your gut health, brain health and future wellbeing, which change is worth making first?

On Tuesday, the Supreme Court ruled 6–3 that federal law protecting prisoners' religious exercise does not extend to a lawsuit brought by an incarcerated Rastafarian man who sought damages after prison officials forcibly shaved his head. The man, Damon Landor, sued both the Louisiana Department of Corrections and several of its officers individually under the Religious Land Use and Institutionalized Persons Act (RLUIPA), which defines the religious rights of people held in institutions that receive federal funding. However, the Court's majority found that the law does not apply to the prison officials named in the suit, as they had not entered into a formal agreement with the federal government. Ad-free podcasts are here!To listen to this podcast ad-free, and to enjoy our subscriber only premium content, go to ReadTangle.com to sign up!Mamdani, Gabbard, and some media controversy.On this week's episode of Suspension of the Rules, the team wades into the wider implications of Mamdani's kingmaking in NYC, the controversy surrounding Tulsi Gabbard's supposed association with a “cult leader,” and a debate about whether Tara Palmeri should have published an interview excerpt a congresswoman asked her to remove. You can watch it ⁠ ⁠⁠here⁠⁠⁠You can read today's podcast⁠ ⁠⁠here⁠⁠⁠ and today's “Under the radar” story ⁠here⁠ and today's “Have a nice day” story ⁠here⁠.You can subscribe to Tangle by clicking here or drop something in our tip jar by clicking here. Take the survey: What do you think of the Supreme Court's ruling? Let us know.Our Executive Editor and Founder is Isaac Saul. Our Executive Producer is Jon Lall.This podcast written by: Audrey Moorehead and audio edited and mixed by Dewey Thomas. Music for the podcast was produced by Diet 75.Our newsletter is edited by Managing Editor Ari Weitzman, Senior Editor Will Kaback, Lindsey Knuth, Bailey Saul, and Audrey Moorehead. Hosted on Acast. See acast.com/privacy for more information.

World Cup!What did humans eat from the Ice Age to the Bronze Age?What supplements should I avoid while undergoing radiation therapy for prostate cancer?What is the treatment for sarcoidosis of the lung? Both my friend and his wife have it.

I'm 78 and had a hysterectomy.  Is it safe for me to eat tofu or other soy foods?Mitopure joins L'Oreal to create a face cream with Urolithin A.Does taking hyaluronic acid orally cause water retention?Can you discuss ETA contained in New Zealand green mussels?What are your thoughts on using vibration devices to help osteoporosis?

If you want a stronger body, a more efficient brain, or just better health overall, your diet is one of the top levers you can pull to make a significant difference. The food you choose to eat has a powerful influence on your health outcomes. On today's show, you're going to learn about nutrition's impact on the human body.  On this episode of The Model Health Show, you're going to hear my interview from The Jesse Chappus Show (formerly The Ultimate Health Podcast), where I shared essential health information, like how your diet affects your genetic expression, and the science behind circadian medicine. You're going to hear my experience with fine-tuning my diet, implementing intermittent fasting, and more. This conversation dives into the problem with eliminating entire food groups and the future of circadian medicine for overall well-being. You're going to learn about how intermittent fasting can aid in fat loss and the power of personalized nutrition. Click play and enjoy the show!  In this episode you'll discover: How my relationship with food evolved throughout my career. (2:48) The science of nutrigenetics and nutrigenomics. (5:23) How adding to my diet (not restricting!) improved my gut health. (9:09) The value of both Western medicine and natural remedies. (13:21) Why your mindset plays an instrumental role in change. (18:31) How being open to change will serve you. (24:37) What circadian medicine is and why it matters. (26:01) The connection between sunlight exposure and cortisol levels. (28:17) How exercise timing can impact your sleep quality. (39:35) Why intermittent fasting can help you burn more body fat. (46:02) The science of fasting mimicking nutrients. (59:01) How coffee influences your brown adipose tissue. (1:03:10) The importance of maintaining muscle mass during the aging process. (1:12:05) What percentage of the average American's diet is ultra-processed foods. (1:19:42) Why omega-3 fatty acids are essential for brain health. (1:23:41)  Items mentioned in this episode include: DrinkLMNT.com/model - Get a truly meaningful dose of electrolytes in a science-backed ratio. Free sample pack with any order. Piquelife.com/model - Doctor-approved, cutting-edge solutions for your head-to-toe health and beauty transformation. Get exclusive savings on bundles & subscriptions. Sleep Smarter - Upgrade your sleep habits with my national bestselling book!  Eat Smarter - Read my national bestselling book for more nutrition tips!  The Jesse Chappus Show - Check out more of Jesse's interviews!  Be sure you are subscribed to this podcast to automatically receive your episodes:  Apple Podcasts Spotify Soundcloud Pandora YouTube  This episode of The Model Health Show is brought to you by LMNT and Pique.  Most people are underhydrated—and it's costing you energy, focus, and performance. LMNT delivers a science-backed electrolyte ratio with no sugar, no junk—just what your body actually needs. Get a free sample pack with any order at drinklmnt.com/model.  Elevate your daily ritual with cutting-edge, doctor-approved teas designed to support your metabolism, skin, and overall vitality. Unlock exclusive savings on bundles and subscriptions at piquelife.com/model. 

Pre-Order My New Book “Mysterious Things” and Help Us Spread the Word: invisiblethings.co --- BUCKLE UP! This episode is CHOCK FULL of powerful insights from bestselling author Cal Newport! This episode is for you if: 1 - You are overwhelmed by the supposed “AI Art-pocalypse” and why this computer scientist doesn't believe the hype (most hopeful take I have ever heard btw!). 2 - You are overwhelmed by admin like e-mail and need a different approach. 3 - You are brainsick from screen time and short form video. 4 - You need a mental emotional motivational boost! This will do it! SHOW NOTES: Cal Newporthttps://calnewport.com Deep Questions with Cal Newporthttps://www.thedeeplife.com/listen/ Producer / Editor: Sophie Miller http://sophiemiller.coAudio Editing / Sound Design: Conner Jones http://pendingbeautiful.coSoundtrack / Theme Song: Yoni Wolf / WHY? http://whywithaquestionmark.comSpotify Playlist of WHY? Songs Used on This Podcast: https://open.spotify.com/playlist/4ZIE7PHG5I1Ddg1BuVGRzj?si=4x_BzDZjQgqSpoaLXdVACg&pi=h4HsIKG0SP6Kg   SPONSORS:SQUARESPACEHead to https://www.squarespace.com/PEPTALK to save 10% off your first purchase of a website or domain using code PEPTALK RULARula patients typically pay $15 per session when using insurance. Connect with quality therapists and mental health experts who specialize in you at https://www.rula.com/peptalk #rulapod Learn more about your ad choices. Visit megaphone.fm/adchoices

Food can be the loudest voice in your head, even when you are not hungry. We sit down with best-selling author Sora Vernikoff, who healed her own compulsive overeating and built a no-diet weight loss program around one core skill: learning how to eat and stop. If you are tired of binge eating, yo-yo dieting, and that constant “what's next to eat” loop, this conversation offers a different path that focuses on behavior change rather than deprivation.We dig into Sora's framework for why overeating and overthinking often feel identical: both are driven by repeating thoughts you do not feel able to release. She breaks down the role of the subconscious mind, why willpower alone keeps failing, and how calming food thoughts can free up the strength to handle the uncomfortable feelings you have been trying to escape. If you have ever felt stuck in a mental replay, whether it's donuts in the kitchen or a fight you cannot stop rehashing, you will recognize yourself here.Sora also teaches a practical technique you can test immediately: the Green Technique. You ask “How much is enough?” and “How much is too much?” before you eat, then you set aside a clear “marker” amount you do not touch. That one move changes the moment from automatic eating to intentional portion control, while still allowing the foods you love. We also cover why diets so often backfire, how rigid rules can trigger binges, and where to find Sora's tools at nodieting.net and OverthinkersCoach.com.If this helps, subscribe, share the episode with a friend who feels stuck, and leave a review so more people can find real-world support for overeating, overthinking, and sustainable weight loss. Support the show Thank you to our sponsor Complete Coverage Football - http://www.completecoveragefootball.com

On Tuesday, the House passed a comprehensive housing affordability bill 358–32, sending the measure to President Donald Trump to sign into law. The bill, titled the 21st Century ROAD to Housing Act, seeks to increase housing supply by rolling back construction regulations, expanding financing options, and restricting institutional investors from purchasing single-family homes in most circumstances. The Senate voted 85–5 to pass the bill on Monday. After originally scheduling a signing ceremony today, Trump announced he would cancel the signing until Congress passes the SAVE America Act. He has not indicated that he would veto the bill.Ad-free podcasts are here!To listen to this podcast ad-free, and to enjoy our subscriber only premium content, go to ReadTangle.com to sign up!A conversation with Tim Urban.Why are otherwise intelligent people unable to resist falling into echo chambers, and how do some get out? That's what Executive Editor Isaac Saul recently discussed with Tim Urban, the creator of Wait But Why and author of the book What's Our Problem? A Self-Help Book for Societies. The conversation flows from there, covering the information ecosystem, artificial intelligence, and the future of journalism. Check it out here!You can read today's podcast⁠ ⁠⁠here⁠⁠⁠ and today's “Have a nice day” story ⁠here⁠.You can subscribe to Tangle by clicking here or drop something in our tip jar by clicking here. Take the survey: What do you think of the 21st Century ROAD to Housing Act? Let us know.Our Executive Editor and Founder is Isaac Saul. Our Executive Producer is Jon Lall.This podcast written by: Isaac Saul and audio edited and mixed by Dewey Thomas. Music for the podcast was produced by Diet 75.Our newsletter is edited by Managing Editor Ari Weitzman, Senior Editor Will Kaback, Lindsey Knuth, Bailey Saul, and Audrey Moorehead. Hosted on Acast. See acast.com/privacy for more information.

When Jenna Fuhrman got pregnant, her prenatal appointments covered tests, screenings, and medications — but barely touched the factor with the deepest influence on fertility, pregnancy, and her child's lifelong health: what she eats. In this episode, she and her father, Dr. Joel Fuhrman, dig into what the research actually says. Most physicians get little nutrition training, even as the science on prenatal nutrition keeps growing — which means parents who want to give their child the best possible start often have to learn this for themselves. Joel and Jenna cover what to eat before conception and through all nine months, and why small dietary shifts can make a lasting difference for both mother and baby. What you'll learn: The surprising link between a father's diet, sperm quality, and miscarriage risk — why this isn't only about the mother Why what both parents eat before conception may shape fertility, miscarriage risk, and a child's long-term health Getting folate from greens and beans, and how it differs from synthetic folic acid Why Dr. Fuhrman recommends algae-derived DHA and EPA over fish during pregnancy Why ferritin testing — not just standard anemia screening — can reveal more about iron status Managing morning sickness and food aversions with small, frequent portions of nuts, seeds, and beans, without losing nutrient density Supporting healthy blood pressure and blood sugar through pregnancy Why a high-animal-protein diet may not be the optimal approach, and how plant protein supports a healthy baby Whether you're trying to conceive, currently pregnant, or planning ahead, this episode offers practical, science-backed guidance for nourishing both mother and baby.

In this episode of the Health, Wellth & Wisdom Podcast, host and head coach, Nicole Hagen answers four listener-submitted questions covering some of the most talked-about topics in nutrition and wellness right now: creatine, the viral "bean diet," GLP-1 medications and mood, and how to navigate the emotional ups and downs of measuring progress.Throughout this episode, you'll learn:Whether creatine is only beneficial for heavy lifters or if women can benefit from taking it tooThe research behind creatine supplementation for muscle health, strength, and agingWhy the viral "bean diet" may be helping some people lose weight The role fiber plays in satiety, blood sugar regulation, and sustainable weight lossWhether GLP-1 medications can affect mood and why some people report feeling emotionally different while taking themWhy scale and measurement fluctuations can feel emotionally charged and how to develop a healthier relationship with progress Practical ways to separate your worth and effort from the number you see on the scaleIf you've ever wondered whether you need the latest supplement, questioned a viral nutrition trend, or felt discouraged when your progress didn't look the way you expected, this episode will leave you feeling informed, reassured, and better equipped to navigate your weight loss journey with more nuance and self-compassion.Apply for 1:1 Nutrition Coaching:https://nutritioncoachingwithnicole.com/1-on-1-coachingCheck your HSA/FSA Eligibility:  https://app.truemed.com/qualify/tm_qual_q0c29x5n9v

Nathan Jones, founder and CEO of Xlear, Inc., reveals xylitol's role in supporting oral and nasal “gateway” microbiomes by selectively starving acid-producing Strep mutans rather than indiscriminately killing bacteria, and warns that harsh mouthwashes can disrupt beneficial oral bacteria linked to nitric oxide production and possibly blood pressure. Jones outlines Spry and Xlear products (gum, mints, toothpaste, mouthwash, dry-mouth “Rain,” and upcoming gummy candies, a new dental probiotic with added nutrients, and a direct-to-consumer oral bacteria test kit with pre/post tracking). He discusses diet, emphasizing sugar as a key driver of cavities and criticizing limited focus on sugar in a Surgeon General oral health report. In part two, Jones describes ongoing and planned legal actions against the FTC over shifting evidentiary standards and reputational damage, then reviews Xlear's allergy and respiratory approach via nasal hygiene, product tiers (regular, Max with quercetin, Rescue botanicals, and a decongestant), and a forthcoming ectoine-based spray to support mucus barrier integrity.

Dr. Hoffman continues his conversation with Nathan Jones, founder and CEO of Xlear, Inc.

Opening Bible Verse:  Ezekiel 24:3-6 IF YOU ARE A NEW LISTENER, WELCOME! BEGIN HERE: This year we are doing my group coaching course together via this podcast! It's free and it only gets better as the year progresses.  In January we began with God at the center of our day and our home. We worked to build the habit of a morning prayer routine. I highly recommend the rosary. It's only about 20 minutes and you'll meditate on the whole life of Jesus. February is the month of decluttering. Saturday episodes have been added to focus on decluttering in the kitchen. Each month will have a different focus area and the Saturday episodes will help you focus on one small section of that room.  In March we decluttered your wardrobe. In April we are moving into budgeting for food. Our Saturday episodes will still be about decluttering. Our declutter focus area for April is your bedroom. In May we dreamed big! June brings us to one of the most useful topics in my group coaching course…meal planning. Ah, the feel of knowing exactly what's for dinner is the most stress-free feeling in the world! Our declutter focus area for June is Hallways/Landings. Give this first episode of 2026 a listen to hear where to begin: 316. Your 2026 Life Overhaul Plan: Faith, Clutter, Debt, Diet and More!  If you've never prayed a rosary or you want to see how you can incorporate it into active decluttering, here is the first episode of my rosary declutter series from last summer. 288. Summer Declutter Series Week Just getting started on your decluttering journey? Give this episode a listen before you begin: 322. Guidelines to Decluttering ***Are you so overwhelmed with clutter that you find yourself unable to make any decisions? Do you plan on decluttering only to find yourself standing in a room confused about where to start? Are you hoping motivation will strike and you'll get it all done in one weekend? If this sounds like you, let's work together. Book a one hour virtual coaching session via Zoom. Together we craft a decluttering plan and I walk you through the process. You'll complete much of the decluttering on your own time at your own pace. I just give you the roadmap and the accountability. Cost $77 per hour. Virtual Coaching Schedule   Not sure what you need? No problem! Book a complimentary 15 minute clarity call. We'll meet via Zoom and see if working with me would benefit you.  Email me at: tightshipmama@gmail.com to schedule a time.   Looking for community of like-minded women? Join the private Facebook community here: Facebook Group Prefer to receive a weekly email with the monthly freebie like a group rosary, group declutter, or budget Q&As?  Join my mailing list here: Monthly Newsletter   For any other inquiries or guest appearances, please email me at: tightshipmama@gmail.com    

Longevity, Trauma Recovery, Circadian Health, Ramadan Fasting & Biohacking Your nervous system may be aging you faster than your diet. Learn how childhood programming, stress, sleep, fasting, resilience, and environment shape longevity, healthspan, metabolism, and human performance, and discover why some of the most powerful upgrades for your biology have nothing to do with supplements, nootropics, or the latest biohacking trends. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Learn more about Dr. Abirached's work at: https://limitlesshuman.ae/ Host Dave Asprey sits down with Dr. Elie Abirached, a Dubai-based longevity and biohacking strategist, Harvard alumnus, founder of Limitless Human, and CEO of Restore Fitness. After being smuggled out of Lebanon during the civil war as a teenager, he built a career helping high performers improve healthspan, resilience, recovery, metabolism, and longevity. Today he is one of the Middle East's leading voices in biohacking, healthy aging, human performance, sleep optimization, and lifestyle-driven longevity. Together, they explore why Dubai has become a global hub for biohacking and longevity, how extreme heat, light exposure, fasting, and modern lifestyle habits affect human biology, and why nervous system health may be one of the most overlooked drivers of long-term performance and anti-aging. They also dive into trauma, neuroplasticity, emotional resilience, metabolism, brain optimization, sleep quality, and the hidden programming that shapes your reactions, relationships, and health outcomes. You'll discover what the Middle East gets right about health and longevity, why resilience may be one of the most important predictors of healthy aging, and how your environment influences everything from recovery and mitochondria to sleep, energy, and mental performance. This episode offers practical insights for anyone interested in biohacking, human performance, longevity, fasting, sleep optimization, metabolism, brain optimization, emotional resilience, and building a stronger, more adaptable nervous system. You'll Learn: • How childhood experiences and unconscious programming influence longevity, healthspan, and human performance • Why nervous system regulation may be one of the most powerful anti-aging tools available • What Dubai's biohacking community gets right about health, recovery, and longevity • How fasting, including Ramadan-style fasting, affects metabolism, energy, and performance • The connection between neuroplasticity, emotional resilience, and brain optimization • How sleep optimization impacts mitochondria, recovery, aging, and cognitive function • Why environmental factors like heat, light exposure, air quality, and circadian rhythm matter more than most people realize • How to improve healthspan without relying solely on supplements, nootropics, ketosis, or the latest biohacking trends • Why stronger biology creates better decision-making, relationships, and long-term success • Practical strategies for building resilience in a world filled with stress, distraction, AI, and information overload Thank you to our sponsors! - Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body. - Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE - Cowboy Colostrum | Get your gut right by going to cowboycolostrum.com/asprey for 25% off of your entire order. - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. Use code DAVE30 for 30% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Elie Abirached, Dubai biohacking, UAE longevity, Middle East biohacking, Lebanon civil war survivor, resilience training, childhood trauma, nervous system regulation, emotional resilience, neuroplasticity, longevity medicine, healthy aging, human performance, sleep optimization, circadian rhythm, Ramadan fasting, intermittent fasting, metabolism optimization, stress adaptation, biological aging, mitochondria health, environmental health, heat adaptation, Dubai longevity, Limitless Human, Restore Fitness, healthspan, recovery optimization, biohacking Dubai, trauma and longevity Resources: • Learn more about Dr. Abirached's work at: https://limitlesshuman.ae/ • Order Dr. Abirached's Book ‘Limitless Human': https://a.co/d/0cwoQFRH • Purchase Dr. Fotuhi's New Book The Invincible Brain: https://a.co/d/0iHCgPpL • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:50 – War Zone Childhood 04:52 – Dubai Mission 08:08 – Childhood Trauma Programming 13:59 – Biohacking in Extreme Heat 19:37 – Fasting & Ramadan 25:15 – Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Isaac Saul interviews Tim Urban, author of the book What's Our Problem?: A Self-Help Book for Societies and creator of the popular blog Wait But Why. Tim does an incredible job at explaining how the big divide between the left and the right doesn't really explain whats going on in our country and what he thinks the solutions could be. You can subscribe to Tangle by clicking here or drop something in our tip jar by clicking here. Our Executive Editor and Founder is Isaac Saul. Our Executive Producer is Jon Lall.This podcast was hosted by: Isaac Saul and audio edited and mixed by Dewey Thomas. Music for the podcast was produced by Diet 75.Our newsletter is edited by Managing Editor Ari Weitzman, Senior Editor Will Kaback, Lindsey Knuth, Bailey Saul, and Audrey Moorehead. Hosted on Acast. See acast.com/privacy for more information.

Ahead of the 2026 midterm elections, candidates aligned with the Democratic Socialists of America (DSA) have broken through in primary races for local and national seats. Headlined by figures like Sen. Bernie Sanders (I-VT), Rep. Alexandria Ocasio-Cortez (D-NY) and Rep. Rashida Tlaib (D-MI), democratic-socialist candidates have challenged incumbents in strongly Democratic areas, seeking to pull the party toward more progressive positions on key issues. Ad-free podcasts are here!To listen to this podcast ad-free, and to enjoy our subscriber only premium content, go to ReadTangle.com to sign up!A conversation with Tim Urban.Why are otherwise intelligent people unable to resist falling into echo chambers, and how do some get out? That's what Executive Editor Isaac Saul recently discussed with Tim Urban, the creator of Wait But Why and author of the book What's Our Problem? A Self-Help Book for Societies. The conversation flows from there, covering the information ecosystem, artificial intelligence, and the future of journalism. Check it out here!You can read today's podcast⁠ ⁠⁠here⁠⁠⁠ and today's “Under the radar” story ⁠here⁠ and today's “Have a nice day” story ⁠here⁠.You can subscribe to Tangle by clicking here or drop something in our tip jar by clicking here. Take the survey: Do you think a democratic socialist could be a viable presidential candidate in 2028? Let us know.Our Executive Editor and Founder is Isaac Saul. Our Executive Producer is Jon Lall.This podcast written by: Will Kaback and audio edited and mixed by Dewey Thomas. Music for the podcast was produced by Diet 75.Our newsletter is edited by Managing Editor Ari Weitzman, Senior Editor Will Kaback, Lindsey Knuth, Bailey Saul, and Audrey Moorehead. Hosted on Acast. See acast.com/privacy for more information.

Nitric Oxide Explained: Vascular Health, Exercise Performance, and N1o1 with Dr. Nathan Bryan, international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. He details NO as a ubiquitous messenger affecting blood flow, erectile function, cognition, exercise performance, endothelial dysfunction, and aging-related declines in NO production. Bryan explains why PDE5 inhibitors like Viagra prolong cyclic GMP signaling but don't fix NO deficiency, and why beet products often fail due to variable nitrate content and inadequate dosing. He outlines his NO lozenge approach that generates NO gas from sodium nitrite and magnesium ascorbate, plus a fermented beet powder drink (NOBeets), and emphasizes the role of oral bacteria (and harms of antiseptic mouthwash/fluoride) in nitrate conversion. They review published endpoints, including flow-mediated dilation, blood pressure effects, inflammation markers, triglycerides, stem cells, plaque regression, applications to Alzheimer's, glaucoma/microvascular disease, safety/dosing considerations, risks of arginine supplementation, and a dual-chamber topical NO serum developed from wound-healing experience.

Dr. Hoffman continues his conversation with Dr. Nathan Bryan, international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. 

Resources for the Community:___________________________________________________________________Linktree Our Favorite ThingsNeed help appealing your GLP-1 dials? www.FindHonestCare.com/KimFind Your US Representatives https://www.usa.gov/elected-officials ______________________________________________________________________Will Medicare finally expand access to GLP-1 medications for obesity? How do you qualify? In this episode, Kim and Kat are joined by community co-host Deb Cooperman and DeeDee, a 70-year-old GLP-1 patient, to discuss Medicare coverage, weight loss, maintenance, and life on GLP-1s after 60.Deb shares her experience paying cash for treatment while hoping to qualify for the new Medicare Bridge Program. DeeDee discusses maintaining her weight loss after losing access to medication, moving to compounded treatment, and growing up in a generation shaped by diet culture.Topics include:• GLP-1 medications after 60• Weight loss and maintenance• Medicare coverage and affordability• Diet culture and obesity• Long-term patient tips and lessons learned• Access to obesity treatmentObesity medicine specialist Dr. Michael Albert joins the conversation to answer common questions about Medicare coverage and the new Medicare Bridge Program, including:• Who qualifies• How the program works• How to apply• Options if you don't qualifyHe also discusses:• Weight loss with GLP-1s in older adults• Protecting muscle mass and prioritizing protein• Side effects to watch for• What to advocate for with your doctorWhether you're on Medicare, approaching eligibility, or helping a loved one navigate obesity treatment, this episode offers practical advice, patient perspectives, and expert guidance.Follow Guests Follow Deb https://www.instagram.com/thedebcooperman https://www.instagram.com/thedebcooperman Follow Dee DeeTikTok https://www.tiktok.com/@deesback  Dr. Michael AlbertInstagram and TikTok: @michaelalbertmdWebsite: MichaelAlbertMD.com#GLP1 #Medicare #MedicareCoverage #ObesityMedicine #WeightLoss #HealthyAging #Zepbound #Wegovy________________________________________________________________________Join this channel to get access to perks:   / @theplussidez______________________________________________________________________#Mounjaro #MounjaroJourney #Ozempic #Semaglutide #tirzepatide  #GLP1 #Obesity #zepbound #wegovy #ObesityCare #PatientAdvocate #GLP1Community #RealGLP1StoriesSend us Fan Mail!Use Honest Care to Appeal GLP-1 Denials. Go to HonestCare.com/Kim  Honest Care can Appeal GLP-1 Denials. Go to FindHonestCare.com/Kim Support the showKim Carlos, Executive Producer TikTokInstagram Kat Carter,  Producer TikTokInstagram 

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzIn this episode, Mikki speaks with Hannah Cabre from Pennington Biomedical Research Center about energy expenditure, body composition, ageing, and what really happens to metabolism through midlife and beyond with a focus on sex differences. Hannah's work uses doubly labelled water data, considered the gold standard for measuring total daily energy expenditure in real-world conditions. This allows researchers to understand what people actually burn across the day, beyond estimates from fitness trackers, calorie equations, or short-term lab measures.Mikki and Hannah discuss the idea that metabolism is “stable” from 20 to 60, whether menopause uniquely affects energy expenditure, why body fat can increase even when scale weight stays the same, and why preserving fat-free mass becomes increasingly important with age.This is a nuanced, evidence-based conversation for anyone interested in metabolism, midlife body composition changes, and what ageing really means for energy needs.https://www.pbrc.edu/research-and-faculty/faculty/cabre-hannah.aspxHannah E. Cabré, PhD, RD, is an Assistant Professor at Pennington Biomedical Research Center and Director of the Aging, Gynecology, and Endocrinology Laboratory. Her research focuses on how female sex hormones influence nutrition, health, performance, and body composition across the lifespan, with a particular interest in sex differences during ageing.Hannah's work explores the importance of skeletal muscle maintenance for long-term health, especially during the menopause transition, and how lifestyle interventions may help mitigate age-related changes in body composition and healthspan.  Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

As more and more people are taking GLP1's such as Ozempic for weight loss, information on the benefits and downsides is changing at a rapid rate. Today Nora and Brian discuss some of the latest findings on the anti-inflammatory and heart protective effects as well as the challenges of muscle loss, fatigue and emotional impacts. With close to 10% of the US population on one of these drugs, understanding how they affect your clients in the studio is essential.Moving Conversation Socials Email: movingconvos@gmail.comIG: @movingconvosFB: Moving ConversationsYoutube: @BrianRicheyBrianIG: @fit4lifedcFB: https://www.facebook.com/brianrichey/NoraIG: nora.s.john.7FB: https://www.facebook.com/nora.s.john.7 https://podcasts.apple.com/us/podcast/moving-conversations/id1669504158?i=1000650467168 https://open.spotify.com/show/6cmgm8T0ZiC5wu6yhXrw9g#movingconversations

Can your DNA unlock the secret to breaking through weight loss stalls? In this episode of the Very Connected Podcast, registered dietitian Sarah Polk joins us to break down how Nutrigenomics testing uses your unique genetic makeup to create a personalized nutrition, supplement, and exercise blueprint. If you are a bariatric patient (pre-op or post-op), using GLP-1 medications like Ozempic, or struggling with unexplained fatigue and weight stalls despite "doing everything right," this episode will explain how your genes dictate your health!  SUBSCRIBE to stay very connected and get more evidence-based bariatric & weight loss resources! https://www.youtube.com/c/ProCareHealth IN THIS EPISODE: Generic "one-size-fits-all" dietary advice doesn't work because our bodies are genetically wired differently. Sarah Polk, MS, RD, LD, explains the science of Nutrigenomics—the study of how our genes influence our response to nutrients, vitamins, caffeine, and exercise. Discover how a simple, 15-second cheek swab can test over 70 different genes to reveal: Why you might have a chronic Vitamin D or Iron deficiency (even while taking supplements). If your body actually tolerates high-fat diets (like Keto) or high-carb diets. Whether caffeine is secretly hurting your sleep, heart health, or anxiety. Your genetic predisposition to snacking, sweet cravings, and obesity. The best type of exercise for your body (strength vs. endurance) and your injury recovery risks. Shop Vitamins and Supplements: https://procarenow.com/   Check out our Event Hub for listings of Bari Connected LIVE Events and Support Groups!   Find Upcoming Support Groups: https://procarenow.com/pages/support-group-hub   Handouts and Resources From Support Groups: https://procarenow.com/pages/support-group-handouts   Subscribe to our YouTube Channel for Bari Connected Replays!   YouTube: https://www.youtube.com/channel/UCh-56bPUphp4gQSM_3ZXKxQ    Join our Bari Connected Group: https://www.facebook.com/groups/857060146125284   Want more ProCare Health Vitamins and Supplements? Follow us on these channels!   Facebook: https://www.facebook.com/procarenow   Instagram: https://www.instagram.com/procarenow/   TikTok: https://www.tiktok.com/@procarenow     Our Guest Speaker's contact information: Sarah Polk, MS, RDN, CSOWM, LD Instagram: @sarahpolknutrition Facebook: SarahPolkNutrition Website: www.sarahpolknutrition.com  Affiliate Link for Sarah Polk Nutrition Sarah Polk is an Affiliate of ProCare Health Code: SPN10 for 10% off your order Link: https://procarenow.com/?ref=SPN10&utm_source=affiliate

Transforming your health is more fun with friends! Join Chef AJ's Exclusive Plant-Based Community. Become part of the inner circle and start simplifying plant-based living - with easy recipes and expert health guidance. Find out more by visiting: https://community.chefaj.com/ ORDER MY NEW BOOK SWEET INDULGENCE!!! https://www.amazon.com/Chef-AJs-Sweet-Indulgence-Guilt-Free/dp/1570674248 or https://www.barnesandnoble.com/w/book/1144514092?ean=9781570674242 GET MY FREE INSTANT POT COOKBOOK: https://www.chefaj.com/instant-pot-download MY BEST SELLING WEIGHT LOSS BOOK: https://www.amazon.com/dp/1570674086?tag=onamzchefajsh-20&linkCode=ssc&creativeASIN=1570674086&asc_item-id=amzn1.ideas.1GNPDCAG4A86S Disclaimer: This podcast does not provide medical advice. The content of this podcast is provided for informational or educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health issue without consulting your doctor. Always seek medical advice before making any lifestyle changes. Watch TrueHealth TV for FREE: https://www.healthpromoting.com/tnhtv Please get the book here now! To get a copy signed by Dr. Goldhamer: https://www.healthpromoting.com/can-fasting-save-your-life To buy on Amazon: https://www.amazon.com/dp/1570674191?linkCode=ssc&tag=onamzchefajsh-20&creativeASIN=1570674191&asc_item-id=amzn1.ideas.1GNPDCAG4A86S&ref_=aip_sf_list_spv_ofs_mixed_d_asin Dr. LIsle and Dr. Goldhamer's book The Pleasure Trap: https://www.amazon.com/dp/1570671974?tag=onamzchefajsh-20&linkCode=ssc&creativeASIN=1570671974&asc_item-id=amzn1.ideas.1GNPDCAG4A86S Dr. Alan Goldhamer is the co-founder of TrueNorth Health Center, a state-of-the-art facility that provides medical and chiropractic services, psychotherapy and counseling, as well as massage and bodywork. He is also director of the Center's groundbreaking residential health education program. Dr. Goldhamer has supervised the fasts of thousands of patients. Under his guidance, the Center has become one of the premier training facilities for doctors wishing to gain certification in the supervision of therapeutic fasting. Dr. Goldhamer was the principal investigator in two landmark studies. The first: "Medically Supervised Water-Only Fasting in the Treatment of Hypertension" appeared in the June 2001 issue of the Journal of Manipulative and Physiological Therapeutics. Its publication marked a turning point in the evolution of evidence supporting the benefits of water-only fasting. The second study: "Medically Supervised Water-Only Fasting in the Treatment of Borderline Hypertension," appeared in the October 2002 issue of the Journal of Alternative and Complementary Medicine. Currently, Dr. Goldhamer is directing a team that is developing a prospective study, incorporating random assignment and long-term follow-up on the cost and clinical outcomes in the treatment of diabetes and high blood pressure with fasting and a health-promoting diet. After completing his chiropractic education at Western States Chiropractic College in Portland, Oregon, Dr. Goldhamer traveled to Australia, where he became licensed as an osteopathic physician. He is the author of The Health Promoting Cookbook and co-author of The Pleasure Trap: Mastering The Hidden Force That Undermines Health and Happiness. Dr. Goldhamer is speaking at the NHA Virtual Conference (June 27-30, 2024). Use this link to get your tickets now: https://events.ringcentral.com/events/nha-conference-2024/registration?utm_campaign=Chef+AJ&utm_source=Affiliate For coaching services: https://www.healthpromoting.com/clinic-services/health-services/coaching-services To register for a stay at TrueNorth: https://www.healthpromoting.com/registration

Mauricio Cardozo conta pro Rambo como foi a experiência presencial na WWDC 2026.

Have you ever lost weight only to realize your mindset never caught up?In this episode, Ethan sits down with Dr. Amy Hornaman to talk about the part of weight loss people rarely discuss: identity. They explore what happens after the scale changes, why maintaining weight loss can feel harder than losing it, and how old beliefs around food, restriction, carbs, and self-perception can stay long after physical transformation. Ethan also shares personal stories from years of dieting and what finally helped create lasting change.For more thoughts and updates from Ethan, sign up for his newsletter here:https://ethansuplee.substack.com/SHOW HIGHLIGHTS00:00 Intro and choosing the real topic02:40 How Ethan made weight loss stick06:30 Why maintaining is harder than dieting14:20 Diet history and chasing quick fixes24:00 Rethinking food rules and calorie awareness30:20 Carb guilt and changing old beliefs36:30 The part of weight loss no one prepares you for39:20 Why identity does not change overnight46:00 Carrying old habits into a new body50:40 Action versus staying stuck in your head53:00 Final reflections and listener questions Hosted on Acast. See acast.com/privacy for more information.

On Sunday, Vice President JD Vance and a team of U.S. negotiators met with Iranian officials in Switzerland to begin peace negotiations. The vice president took a leading role in finalizing the memorandum of understanding (MOU) that Iran and the U.S. signed last week, and on Sunday, Vance called for a broad reset of relations after nearly four months of war. He also rebuked Israeli politicians for their criticism of the recent MOU, drawing scrutiny from some conservatives and raising broader questions about his prospects as a future party standard-bearer. Ad-free podcasts are here!To listen to this podcast ad-free, and to enjoy our subscriber only premium content, go to ReadTangle.com to sign up!The Father's Day episode.In a special Father's Day edition of Suspension of the Rules, Isaac, Ari, and Kmele are joined on the podcast by two guests: Executive Producer Jon Lall and Isaac's father (and Tangle editor) Bailey Saul. The five of them represent different phases of fatherhood — from soon-to-be father to dad of two school-aged children to three-kid veteran (and grandfather) — and discuss what they've learned through their separate experiences. You can listen to the special edition here.You can read today's podcast⁠ ⁠⁠here⁠⁠⁠ and today's “Under the radar” story ⁠here⁠ and today's “Have a nice day” story ⁠here⁠.You can subscribe to Tangle by clicking here or drop something in our tip jar by clicking here. Take the survey: How much responsibility do you think Vice President Vance has for negotiating an end to the war in Iran? Let us know.Our Executive Editor and Founder is Isaac Saul. Our Executive Producer is Jon Lall.This podcast written by: Isaac Saul and audio edited and mixed by Dewey Thomas. Music for the podcast was produced by Diet 75.Our newsletter is edited by Managing Editor Ari Weitzman, Senior Editor Will Kaback, Lindsey Knuth, Bailey Saul, and Audrey Moorehead. Hosted on Acast. See acast.com/privacy for more information.

Bingeing can be painful and costly, but it often persists because it is doing a job.Not working because it is harmless or because you want to keep doing it, but because it may have been doing something important for you. Bingeing may provide relief, comfort, rest, numbness, pleasure, rebellion, privacy, or a way to get through moments that feel impossible.In this episode, we look at bingeing as a coping strategy that may have helped you survive, especially if it began when you were young and had fewer choices. The goal is not to romanticize bingeing, but to understand what need it has been meeting so you can begin meeting that need earlier, more directly, and with less harm.New to the show? Start Here: https://breakingupwithbingeeating.transistor.fm/start-herePick the listening path that fits what you're dealing with right now.

What if the reason tracking macros isn't working anymore has nothing to do with your discipline? In this episode, I break down one of the most common frustrations I hear from women: "I used to track macros, lose weight, and see results. Now I do the exact same thing and nothing happens.".  I want to share the story of how I once believed macros were the magic solution to fat loss, only to realize they were never the answer. They were simply a tool. We'll talk about why there is no perfect macro split, how the body constantly adapts to what we do, and why staying on the same nutrition plan for months or years can actually become part of the problem. I explain how functional nutrition often involves strategically changing calories, carbohydrates, fats, and protein to stay ahead of those adaptations rather than fighting against them. You'll learn why there may be a time for low-carb eating, a time for higher calories, a time for lower protein, and a time for a more balanced approach. Most importantly, we'll discuss how understanding macros can still be incredibly valuable when they're used within the right context. Today, I personally track my macros, not to lose weight, but to make sure I'm eating enough and maintaining the right balance for my current season of life.  If you've been wondering why your old nutrition strategy isn't producing the same results anymore, this episode will help you understand what changed and how to start working with your body instead of against it.   Time Stamps:   (1:47) Life Updates (3:06) My Macro Tracking Journey (4:47) Why Macro Tracking Gets A Bad Rap (8:22) Recent Client Example (12:32) Where To Start --------------------- Find Out More Information on Vital Spark Coaching --------------------- Follow @vanessagfitness on Instagram for daily fitness tips & motivation.  --------------------- Download Our FREE Metabolism-Boosting Workout Program --------------------- Join the Women's Metabolism Secrets Facebook Community for 25+ videos teaching you how to start losing fat without hating your life! --------------------- Click here to send me a message on Facebook and we'll see how I can help or what best free resources I can share! --------------------- Interested in 1-on-1 Coaching with my team of Metabolism & Hormone Experts? Apply Here! --------------------- Check out our Youtube Channel! --------------------- Enjoyed the podcast? Let us know what you think and leave a 5⭐️ rating and review on iTunes!

Should you stop taking glucosamine based on a new study linking it to Alzheimer's? What's behind the spate of “Tai Chi Walking” social media posts? Undereye “festoons”—what to do about them? Are antibiotics the only treatment for SIBO? Vaping after smoking hikes risk for lung cancer.

Why aren't there more medical insurance plans that cover alternative medicine? Solutions for Long Covid; MK7 vitamin K slows arterial calcification; Keto diet shows promise for treatment of anorexia; It's not so much salt restriction—it's the dietary sodium/potassium ratio in hypertension; Study finds multivitamins don't keep you from getting Covid—but when you get it, it's milder; Incidence of social anxiety disorder is soaring among young people.

Jay breaks down why most “metabolism reset” programs fail and reveals a smarter, research-backed 30-day approach that actually works. Drawing from decades of experimentation and human studies, he dives into the real science of adaptive thermogenesis, the dangers of yo-yo dieting, and how to rebuild your hormonal environment for lasting results.Key topics include:Strategic diet breaks at maintenance calories to reverse metabolic slowdownHigh-protein intake and resistance training to positive muscular failure (PMF)Alternate-day fasting, metabolic flexibility, and smart HIIT protocolsThe role of peptides and targeted compounds to accelerate repairWhy muscle preservation is the ultimate key to a thriving metabolismIf you're tired of crash diets that leave you worse off, this conversation delivers practical, no-BS strategies to reignite your metabolism, preserve muscle, and build sustainable habits that support your long-term health, energy, and purpose.Jay also shares insights from his 30 Days 2 Shredz protocol and Metabolic Awakening framework—tools designed to help you stop fighting your biology and start working with it.https://jaycampbell.com/Become a supporter of this podcast: https://www.spreaker.com/podcast/i-am-refocused-radio--2671113/support.Subscribe now at YouTube.com/@RefocusedNetworkThank you for your time. 

In this solo episode, Dr. Mike T. Nelson introduces the concept of coaching leverage—the idea that effective coaching means multiplying physiological impact by a client's realistic ability to change. Why sleep is a physiological powerhouse but a coaching nightmare The coaching leverage formula: physiology × psychology Why protein ranks #1 (score: 81) and sleep ranks #8 (score: 20) How to stop majoring in the minors with your clients The eight interventions inside the Flex Diet Certification Why following a proven system beats reinventing the wheel The Flex Diet Certification closes tonight (Monday, June 22, 2026) at midnight Pacific. Get details here. Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter

Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/Try Suppgrade Labs: https://shopsuppgradelabs.com/If you're eating clean, taking the right supplements, and still feel exhausted and mentally foggy - the problem isn't your protocol. Your body has a built-in cellular cleanup system that determines whether any of those inputs actually work, and right now it's almost certainly switched off. In this video, I break down what that system is, how chronic stress and all-day eating suppress it without you ever feeling it, and the specific compounds that flip the longevity switch back on through independent biological pathways that nothing else touches.Thank you to our sponsors!ECHO Water | Go to http://echowater.com/daveand use code DAVE10 for 10% off your ECHO Flask.EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVETimestamps:0:00 – The Longevity Switch0:47 – Why Mitochondria Matter2:28 – What Mitophagy Is2:46 – How Mitophagy Works4:18 – What Shuts It Off8:54 – The Damage Compounds9:22 – How to Turn It Back On10:31 – Signal 1: Fasting11:48 – Signal 2: Exercise (REHIT)12:30 – Signal 3: Cold Exposure13:22 – Signal 4: NAD+14:29 – Signal 5: Urolithin A and SpermidineConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Three of our favorite segments from the week, in case you missed them. [00:00] What Are Ultra-Processed Foods?  [29:31] Ultra-Processed Foods and Colon Cancer  [49:27] Ultra-Processed Foods Policy Proposals  If you don't subscribe to the Brian Lehrer Show on iTunes, you can do that here. Photo: Packets of chips are on display at a supermarket in Mumbai, India, on September 7, 2025. (Photo by Indranil Aditya/NurPhoto via Getty Images) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Sugar-Free Diets Disrupted Gut Microbiome and Metabolism A 16-week sucrose-free, low-fat diet study presented at ENDO 2026 found mice developed insulin resistance, impaired glucose tolerance, gut microbiome imbalance, intestinal inflammation, and fatty liver disease signs despite no weight gain or calorie difference. Host Dave Asprey breaks down why eliminating sugar entirely may be more detrimental than previously thought, the gut-bacteria-to-metabolism cascade that explains the metabolic damage, and why balanced nutrition matters more than simply removing sugar from your stack. Sources: https://www.sciencedaily.com/releases/2026/06/260614011843.htm https://www.medicalnewstoday.com/articles/how-eliminating-sugar-may-alter-the-gut-microbiome-mouse-study https://nypost.com/2026/06/13/health/going-sugar-free-can-mess-with-your-gut-and-metabolism/ ~~ Taurine Did Not Boost Acute Aerobic Performance A randomized, triple-blind, cross-over study of 16 physically active young adults found acute 1-gram taurine ingestion one hour before exercise produced no significant improvements in peak oxygen consumption, time to exhaustion, respiratory compensation point, or lipid/glycolytic metabolism variables. Host Dave Asprey explains why taurine remains popular in energy drinks and pre-workouts despite limited scientific evidence, what dosages and activity types future research should test, and why a reality check on a billion-dollar supplement category is exactly the kind of truth biohackers need. Sources: https://pubmed.ncbi.nlm.nih.gov/42268287/ https://www.sciencedaily.com/releases/2026/06/260611024609.htm ~~ Copper Therapy Improved Memory and Reduced Alzheimer's Proteins in Mice Lab trials from Monash University published in ACS Chemical Neuroscience found Cu(ATSM), a copper-delivery compound, increased P-glycoprotein abundance by 24.1 percent at the blood-brain barrier, reduced toxic amyloid-beta by 42 percent over 56 days, and improved spatial learning by nearly 44 percent in an Alzheimer's mouse model. Host Dave Asprey breaks down why repairing the brain's waste-clearing pump is a potential new therapeutic avenue for neurovascular dysfunction, why Cu(ATSM) has strong potential to fast-track into human clinics since it's already tested for Parkinson's and ALS, and why biometal therapies like this could be the next frontier in Alzheimer's treatment. Sources: https://www.news-medical.net/news/20260615/Lab-trials-prove-copper-therapy-enhances-cognitive-function-and-spatial-learning.aspx https://www.monash.edu/news/articles/copper-drug-restores-memory-and-clears-toxic-alzheimers-proteins https://pubs.acs.org/doi/10.1021/acschemneuro.6c00252 ~~ Socioeconomic Factors Biologically Embedded in Children's Brains A study of 2,300+ 9- and 10-year-olds published in Science found socioeconomic factors—household income, education, neighborhood quality—were the dominant variable affecting brain development, with MRI-visible differences in sensory processing and motor control regions linked to less sleep, more stress, and higher social media use in lower-income neighborhoods. Host Dave Asprey explains why socioeconomics became “biologically embedded” in preteen brains, how sleep-stress-screen circuits alter wakefulness and alertness, and why earlier studies focusing on IQ or mental health without accounting for environment may require reevaluation. Sources: https://www.npr.org/2026/06/11/nx-s1-5849937/child-brain-development-stress-sleep-neighborhood-economics https://abcdstudy.org/ ~~ Strength Training Sweet Spot for Longevity Is 90–120 Minutes Per Week A 30-year observational study of 147,374 participants published in the British Journal of Sports Medicine found 90–119 minutes per week of strength training delivered 13 percent lower all-cause mortality, 19 percent lower cardiovascular mortality, and 27 percent lower neurological mortality, with no additional benefit above 120 minutes. Host Dave Asprey breaks down why more isn't always better when it comes to resistance training, why combining strength with aerobic exercise dropped mortality risk by 45–58 percent at highest levels, and why 15–20 minutes a day or 30–40 minutes three times weekly is the minimum effective dose for longevity. Sources: https://www.sciencedaily.com/releases/2026/06/260611024609.htm https://academic.oup.com/sleep/article/48/8/zsaf127/8129074 https://www.bmj.com/content/bsjspor/early/2025/06/11/bjsports-2025-110503 ~~ This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on sugar-free diet metabolic risks, taurine supplement efficacy, copper-based Alzheimer's therapeutics, childhood environmental brain development, and strength training longevity dosing. Host Dave Asprey connects preclinical animal data, randomized human trials, observational cohort research, and population neuroscience into actionable frameworks for extending healthspan, optimizing metabolism, and staying ahead of the science. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: sugar-free diet gut microbiome, insulin resistance sugar elimination, taurine aerobic performance, taurine supplement myths, Cu(ATSM) copper Alzheimer's therapy, blood-brain barrier P-glycoprotein, amyloid-beta reduction copper drug, spatial learning Alzheimer's mouse, socioeconomic brain development children, ABCD Study brain MRI, childhood biohacking environment, strength training longevity 90-120 minutes, British Journal Sports Medicine strength, weekly strength training dose, all-cause mortality resistance training, biohacking news 2026, longevity researchThank you to our sponsors! - Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body. - Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Intro 0:20 – Story 1: Copper & Alzheimer's 2:42 – Story 2: Sugar-Free Diet 4:05 – Story 3: Strength Training Minimum Dose 5:48 – Story 4: Childhood Environment & Brain Development 7:42 – Story 5: Taurine 9:49 - Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ketamine Therapy, MDMA, Psilocybin, and the Science of Psychedelic Assisted Healing Most people struggling with depression, anxiety, and trauma have never felt safe in their nervous system, and the treatments they have been prescribed are making that worse. This episode breaks down the neuroscience of psychedelic therapy, why ketamine is the safest and most accessible starting point, how MDMA triggers a BDNF dependent pathway that repairs trauma all the way down to the epigenetic code, and why your antidepressant may be blocking the very brain states required for real healing. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Order Dr. Rabin's Book ‘A Simple Guide to Being Alive': https://apolloneuro.com/pages/a-simple-guide-to-being-alive Host Dave Asprey sits down with Dr. Dave Rabin, MD, PhD, a senior research scientist at the Florida Institute for Human and Machine Cognition, Executive Director of The Board of Medicine, and co-founder and Chief Medical Officer of Apollo Neuroscience. Dr. Rabin received his MD and PhD in neuroscience from Albany Medical College and specialized in psychiatry at the University of Pittsburgh Medical Center. He has spent 20 years studying chronic stress and non-invasive therapies for treatment-resistant illness, and his primary research on MDMA assisted therapy for severe PTSD has demonstrated that trauma can be reversed at the epigenetic level, offering a genuine path to a cure. His upcoming book A Simple Guide to Being Alive publishes June 1, 2026 and is a science-backed manual for anyone who has ever felt overwhelmed by the modern world. Dave and Dr. Rabin break down why nearly 50% of people prescribed psychiatric medication never achieve remission, why SSRIs and SNRIs physically block the brain states required for emotional healing, and why the FDA rejected MDMA therapy after three trials showed an 88% response rate. They dig into the exact BDNF pathway that makes MDMA and ketamine so transformative, how psychedelics amplify safety learning in the amygdala at the molecular level, and why trauma passes down up to 14 generations through epigenetic code that can now be measured and repaired. They also cover why your breathing rate at the doctor's office is already a stress signal nobody is reading, how your smartphone puts your nervous system into a chronic fear state before you even get out of bed, and why ketamine is the right starting point for anyone curious about psychedelic therapy right now. You'll Learn: Why nearly 50% of psychiatric patients never get better and what treatment-resistant actually means How ketamine therapy works, why it is legal in every state, and why it is the safest place to start The exact BDNF pathway through which MDMA repairs fear extinction in the amygdala How MDMA assisted therapy produces measurable epigenetic repair of the cortisol receptor gene damaged by trauma Why SSRIs and SNRIs block the insula mediated brain states required for real emotional healing Why combining serotonergic psychedelics with SSRIs puts you at risk of life-threatening serotonin syndrome Why trauma passes down up to 14 generations and what you can do to stop the cycle now Why smartphones put your nervous system into a toxic overstimulation state before the day even starts How the FDA rejected MDMA therapy after 88% of patients responded and who paid to make that happen Thank you to our sponsors! - Qualia | If you want to take the guesswork out of maintaining high NAD+ levels as you age, go to www.qualialife.com/daveNAD to get clinically proven Qualia NAD+ backed by a 100 day money back guarantee and code DAVENAD at checkout gets you an extra 15% off. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE - OneSkin | For a limited time, try OneSkin with 15% off at oneskin.co/DAVE. - LMNT | Right now you can get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at drinkLMNT.com/dave Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dave Rabin, Dr. Dave Rabin, Apollo Neuroscience, A Simple Guide to Being Alive, ketamine therapy, MDMA assisted therapy, psilocybin therapy, psychedelic assisted therapy, treatment-resistant depression, treatment-resistant mental illness, BDNF pathway, fear extinction amygdala, vagus nerve activation, trauma epigenetics, cortisol receptor gene, epigenetic repair, serotonin syndrome, SSRI alternatives, MDMA BDNF, ketamine BDNF, nervous system safety, autonomic nervous system, parasympathetic nervous system, generational trauma, trauma self-trust, MAPS MDMA trial, FDA MDMA rejection, pharmaceutical interference MDMA, breathing rate stress, smartphone nervous system, Apollo Neuro wearable, Board of Medicine, theboardofmedicine.org, insula cortex, psychedelic safety protocol, ketamine legal therapy, MDMA 88 percent, bottom-up learning psychedelics, trauma fractured self-trust, 14 generations trauma, stress breathing range Resources: • Order Dr. Rabin's Book ‘A Simple Guide to Being Alive': https://apolloneuro.com/pages/a-simple-guide-to-being-alive • Purchase Dr. Fotuhi's New Book The Invincible Brain: https://a.co/d/0iHCgPpL • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:34 – Dave Rabin Introduction 05:01 – Psychedelics and Psychiatry 08:35 – Psychedelic Safety and Dosing 14:53 – Serotonin Syndrome Warning 21:17 – Vagus Nerve and Safety 27:36 – Smartphones and Chronic Stress 34:18 – Defining Trauma 38:00 – Trauma and Epigenetics 40:23 – MDMA Cortisol Gene Repair 44:44 – Therapy vs. Medicine Alone 49:15 – FDA MDMA Rejection 55:35 – Ketamine Personal Experience 59:15 – Closing and Book Recommendation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We've been taught to treat chronic diseases as isolated problems to be diagnosed and managed. But these conditions may have more in common than conventional medicine has traditionally recognized. On this episode of The Dr. Hyman Show, I'm joined by physician and researcher Dr. Terry Wahls, who transformed her understanding of disease after developing progressive multiple sclerosis. We discuss the emerging science behind mitochondria, inflammation, nutrition, the microbiome, and why creating health may be just as important as treating disease itself. We explore: What Dr. Wahls discovered about cellular health while searching for answers beyond conventional treatment Why mitochondria may play a central role in conditions like MS, Alzheimer's, Parkinson's, depression, and chronic fatigue How food, sleep, movement, and stress directly influence inflammation, energy production, and brain health Why focusing only on symptom suppression may overlook the deeper biological dysfunction driving chronic disease What “creating health” actually looks like in practice—and how small daily habits can influence how you feel and function over time What makes this conversation so compelling is that Dr. Wahls' story challenges many of the assumptions we have about chronic disease and recovery. For me, it really highlights how profoundly nutrition, sleep, movement, and stress can shape the body's ability to adapt and recover over time. View Show Notes From This Episode Sign up for Dr. Hyman's Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by fatty15, Big Bold Health, Timeline, BON CHARGE, BIOptimizers, and Made In. Head to fatty15.com/HYMAN today and use code HYMAN for 15% off your 90-day subscription Starter Kit. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Visit madeincookware.com and use code HYMAN10 for 10% off your order. (0:00) Dr. Terry Wahls' illness journey, Dr. Mark Hyman's intro, and sponsor mentions (2:54) Dr. Wahls and Dr. Hyman discuss their medical histories (4:00) Dr. Wahls' experience with multiple sclerosis (7:08) Dietary changes and physical improvements (9:09) Environmental factors in autoimmune diseases (11:17) Resistance in the medical system to new approaches (12:26) Integrating basic science into clinical practice (15:32) Mitochondrial support supplements (20:24) Mitochondria's role in energy-intensive tissues (22:11) Functional medicine and Dr. Wahls' continued health journey (23:49) Nutrient-focused dietary approach and recovery (26:13) Development and application of the Wahls diet (27:35) Nutrient-rich food categories and health benefits (30:11) NIH funding and functional medicine research potential (34:00) Success stories from the therapeutic lifestyle clinic (39:28) Creating health versus treating disease (44:10) Expanding research to other chronic illnesses (45:40) Latest clinical trials and future research directions (47:49) Advances in chronic disease treatment science (49:05) Predicting diet effectiveness: microbiome and genetics (50:00) Microbiome research and multiple sclerosis (51:18) A new theory of human biology in medicine (53:01) Creating health through lifestyle changes (55:13) Need for multimodal interventions in research (58:20) Funding challenges and philanthropy's role (59:08) Comprehensive approaches to complex diseases (1:01:05) Potential to reverse genetic diseases with lifestyle changes (1:07:24) Strategies for creating a healthy human (1:08:01) Upcoming research and initiatives by Dr. Wahls

Skin Cancer Prevention, Anti-Aging Biohacking, and the Melanoma Detection Gap Most dermatologists are missing melanoma, and a board-certified skin cancer specialist explains exactly why, and what to do about it. This episode covers the detection tool that finds 10 times more melanomas, the real truth about sunscreen chemicals, the biohacking peptide that can hide cancer on your skin, and the cheap anti-aging drug that most people have never tried. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Michael Christopher, a board-certified dermatologist and expert dermoscopist recognized for his work in early melanoma detection. Through consistent, evidence-based use of dermoscopy, he identifies between 150 and 215 melanomas annually, far exceeding national and state averages and exposing a critical gap in standard skin cancer screening. Dr. Christopher speaks regularly on prevention, early detection, and systemic failures in dermatology training across health, wellness, and longevity-focused media, and has made it his mission to change the standard of care before more people die from a cancer that is almost always curable when caught early. Dave and Dr. Christopher break down why a standard skin exam with no additional tools is essentially a guess, how dermoscopy changes everything, and why most dermatologists who claim to use it actually cannot interpret what they see. They get into the real risk factors for rising melanoma rates, what sunscreen labels are not telling you, and how melanotan and other biohacking peptides interact with your skin cancer risk in ways that matter. They also cover tretinoin as one of the most evidence-backed anti-aging and skin optimization tools available, how red lighttherapy supports mitochondria function and skin rejuvenation, and what parents should know about protecting their kids' skin for long-term longevity You'll Learn: Why most dermatologists miss melanoma and what the detection gap actually looks like What dermoscopy is, how it works, and why you should ask for it by name How melanoma survival drops from 99% at stage one to 73% at stage three What the Prop 65 cancer warning on most pharmacy sunscreens actually means Why visible light can darken your skin even when you wear sunscreen How melanotan activates melanocortin receptors and why that may affect melanoma risk What Retin-A does to collagen, the epidermis, and long-term skin aging How AI is entering dermoscopy and where it still falls short The right concentration of tretinoin to start with and how to get through the adjustment period What parents should do now to protect their kids from melanoma later Thank you to our sponsors! -Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com.-Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body.-Timeline | Go to timeline.com/dave and you'll get an additional 20% off your first month-Redmond Real - Leaf Toothpaste | Go to https://redmond.com/asprey and use code ASPREY for 15% off your first order.Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Michael Christopher, Dr. Michael Christopher, melanoma detection, dermoscopy, dermatoscope, skin cancer screening, melanoma prevention, early melanoma detection, skin cancer biohacking, sunscreen toxins, Prop 65 sunscreen, mineral sunscreen, zinc oxide, titanium dioxide, melanotan, melanocortin, skin aging, anti-aging, tretinoin, Retin-A, retinol, skin rejuvenation, collagen, red light therapy, mitochondria, UV exposure, UVB light, skin cancer longevity, melanoma survival rate, squamous cell carcinoma, functional medicine, human performance, longevity, biohacking, supplements, skin optimization, dermoscopy AI, skin cancer AI, visible light tanning, omega-6 sunburn, astaxanthin, skin health, melanoma staging, skin exam, skin cancer prevention Resources: • Learn More About Dr. Christopher's Work At: https://www.instagram.com/michael_christopher_md/ • Purchase Dr. Fotuhi's New Book The Invincible Brain: https://a.co/d/0iHCgPpL • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 1:41 – Guest Introduction 3:59 – Dermatoscope Explained 12:27 – Melanoma Rising: Why 16:57 – Melanotan & Sun Risk 21:14 – Melanoma & Longevity 22:31 – Stage 1 vs Stage 3 26:05 – Retin-A Deep Dive 38:53 – Loose Skin Solutions 41:26 – Kids' Skin Health See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.