Podcasts about Iga

Carlos Alcaraz and Juan Carlos Ferrero have officially parted ways after seven years. In this week's Served Five Setter, we break down the split heard 'round the world, including reactions from Toni Nadal and Feliciano Lopez. Is Carlitos ready for the next step without his mentor? Plus, a massive shakeup in Madrid as Garbiñe Muguruza takes charge, the ATP finally adopts a strict Heat Rule for 2025, and Iga Świątek gives back to the next generation in a big way. COMMENT BELOW What was your favorite racket story from this week?

Join hosts Jeff Steadman and Jim McDonald for a special live episode recorded on location at Identiverse DC! In this interactive session, Jeff and Jim host a game of "Majority Rules," where the audience competes not to answer correctly, but to guess the most popular answer in the room.The game covers a wide range of topics, from the trivial (worst conference swag and the official uniform of an IAM architect) to the technical (securing API keys, the biggest bottlenecks in IGA, and the primary causes of role explosion).Things get intense halfway through with the introduction of the Battle Royale rules, where picking the minority answer sends a player's score back to zero. Watch to see who survives the explosions and takes home the grand prize.Connect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at http://idacpodcast.comChapter Timestamps00:00 Intro to Identity at the Center Live00:36 Explaining the Rules of Majority Rules04:25 Question 1: The Worst Conference Swag06:00 Question 2: Replying to Access Denied07:05 Question 3: AI in Identity Management08:40 Question 4: Favorite MFA Method10:12 Question 5: Least Favorite Auth Factor11:15 Turning up the Heat: Battle Royale Mode12:10 Question 6: Why RBAC is Difficult at Scale13:30 Question 7: The IAM Architect Uniform14:50 Question 8: Best Place to Hide a Secret16:15 Question 9: Protocols You Secretly Miss17:25 Question 10: Most Hated Specialized Key18:40 Question 11: Conference Responsibilities20:00 Question 12: Securing API Keys21:20 Question 13: Secrets to Surviving Keynotes22:55 Question 14: The Biggest Bottleneck in IGA24:45 Question 15: Causes of Role Explosion25:50 Question 16: What Breaks First After a Schema Update26:40 Final Question: Fastest Way to Confuse a User27:40 Crowning the WinnerKeywordsIDAC, Identity at the Center, Jeff Steadman, Jim McDonald, Identiverse, Identiverse DC, IAM, Identity and Access Management, Cybersecurity, InfoSec Game Show, Live Podcast, Majority Rules, MFA, IGA, API Security, RBAC, Role Explosion, Tech Humor, Cyberrisk Alliance

In this 2025 Season Recap, Andy Roddick, Jon Wertheim, and Producer Mike dig into their “winners and unforced errors” of the tennis season: from successful US Open mixed doubles exhibition to the much-criticized extended Masters 1000 events. They debate the sport's failure to empower creators and players to use match footage, and the power struggle over prize money and revenue share at the Grand Slams. The crew also relives Sinner–Alcaraz's unforgettable Roland Garros epic, Coco Gauff's and Iga Świątek's seasons, Sabalenka's resilience, and the booming depth of American tennis on both tours. Finally, they zoom out to why tennis is “having a massive moment” globally and why that makes the structural mistakes and missed opportunities even more frustrating. COMMENT BELOW What was your biggest “winner” and “unforced error” of the 2025 tennis season?

Susan Diane Wolff Cappel was a 19‑year‑old woman from Newcomerstown, Ohio, who mysteriously disappeared on March 16, 1982. She was last seen leaving her job at the local IGA grocery store, where witnesses reported her speaking briefly with the driver of an older model, light blue car before getting inside. She has never been seen again. If you have any information about why Susan went missing or who was responsible for her disappearance, please call the Tuscarawas County Sheriff's Office @ 330-339-2000 or the Newcomerstown Police Department @ 740-498-6161. ⁠Click here⁠ to join our Patreon.  ⁠Click here⁠ to get your own Inhuman merch.  Connect with us on ⁠Instagram⁠ and join our ⁠Facebook group⁠.  To submit listener stories or case suggestions, and to see all sources for this episode: ⁠https://www.inhumanpodcast.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

W dzisiejszym magazynie sportowym: Polacy Mistrzami Świata drużyn 6 - osobowych w piłce nożnej; plany organizacji letniej olimpiady w 2040 roku w Polsce; Iga Świątek i Klaudia Zwolińska nominowane w konkursie na najlepszą sportsmenkę 2025 roku.

Prezydent, premier, marszałek sejmu, RobertLewandowski, Iga Świątek, Orlen, Pekao – można mnożyć nazwiska i nazwy firm wykorzystywanychnielegalnie w reklamach fałszywych inwestycji zalewających internet. Kradzież na masową skalę kosztuje Polaków setki milionów złotych. Jak walczyć z patoreklamamii czy w ogóle się da?Reklamy fałszywych inwestycji to zmora internetu, a w szczególności mediów społecznościowych. Przestępcy wykorzystują w nich zdjęcia i deepfejkowe filmy z udziałem znanych osób, żeby uwiarygodnić oszustwoi namówić ludzi do kupowania nieistniejących aktywów. W 2024 r. NASK naliczył blisko 150 nazwisk polityków, biznesmenów, lekarzy, duchownych, dziennikarzy,sportowców i celebrytów, których  wizerunekskradziono w celach przestępczych. Krótsza jest lista firm, których logo przestępcy posługują się równie chętnie. Są to głównie znane marki spółek skarbu państwa: Orlen, PKO BP, Pekao, Poczta Polska, ale też prywatnych marek, jak InPost, czy Tesla.W podcaście rozmawiam z Pawłem Orzechowskim,który w Orlenie zajmuje się m.in. walką z patoreklamami. Dość skutecznie. Jeszcze kilka miesięcy temu wystarczyło wpisać w Google frazę „inwestycje w Orlen” a wśród czterech linków sponsorowanych trzy prowadziły do stron zfałszywymi inwestycjami. Od dłuższego czasu ich nie ma – dzięki współpracy Google. Bez wsparcia gigantów internetowych zwalczanie reklam jest jak walka z wiatrakami. Tak jest na Facebooku, Instagramie, gdzie pseudoreklamy mnożą się jak króliki Rojtszwańca.Zapraszamy do wysyłuchania i obejrzenia rekamy, bo w wideokaście pokazujemy przykłady fejkowych reklam.

Double médaillé olympique et champion du monde, Alexandre Despatie nous plonge (littéralement) dans son parcours exceptionnel.Athlète légendaire devenu animateur, communicateur et ambassadeur engagé, il nous partage ses souvenirs, ses défis et ses passions avec authenticité, humour et générosité.Découvrez son engagement unique pour les 24h de Tremblant, où il se donne le défi de skier 25 heures.️Une conversation drôle, inspirante et authentique avec un champion… à sa façon.Écoutez ou regardez l'épisode maintenant ️️Soutenez le 24 heures de Tremblant :Parce qu'une enfance sans cancer, ça commence avec un don Isa, Femme de Sports, présenté par IGA, diffusé chaque jeudi à 16h30 sur TVA SportsSuivez-moi également sur nos médias sociaux pour plus de contenu: Facebook : / isa.femme.de.sport Instagram : / isa.femme.de.sports X : https://x.com/isabelleethier

We are celebrating your Chaotic Christmas moments thanks to IGA, Poppy had a few hiccups getting registered as being born and Little Wins of the Week!See omnystudio.com/listener for privacy information.

Kalmer Kase on üks Eesti kogenumaid konstellööre ja konstellatsioonide õpetajaid, kellel on üle 18 aasta kogemust nii perekonstellatsioonide, töösuhete kui ka struktuursete konstellatsioonide valdkonnas. Ta on õppinud konstellatsioone Riias, Kiievis ja Moskvas ning tegeleb täna peamiselt konstellööride väljaõppe, supervisioonide ja konstellatsioonide praktilise teostamisega nii Tallinnas kui Tartus. Kalmer on Holistilises Instituudis ja Universuse Koolitustel olnud aastaid üks keskseid koolitajaid ning tema juhendamisel on kasvanud Eesti konstellatsioonide põlvkond, kes toetab inimesi peremustrite, organisatsiooniliste dünaamikate ja sügavate sisemiste segaduste lahendamisel. Tema värske raamat "Konstellatsioonid – kas karta või kasutada?" aitab murda müüte ja hirme, mis on selle teraapiavormi ümber, ning loob inimestele selgema mõistmise, kuidas konstellatsioonid töötavad, miks need mõjuvad ja miks mõnda inimest see meetod tõmbab, teist aga hirmutab. --- PODCASTI SPONSORID MILLION MINDSET KIRJASTUS – Kasuta sooduskoodi “chriskala” ja saad -10% kõikidelt raamatutelt.

You've worked on some of the most iconic consumer-loved brands—how do you translate that big-brand thinking into IGA's decentralized, independent retail model?How has your direct marketing mindset influenced the way IGA approaches shopper insights, loyalty programs, and CRM in today's fragmented retail environment?What role does storytelling play in building richer customer relationships across IGA's network of stores, especially when trying to drive both local and national relevance?With so much focus on digital innovation and shopper experience, how is IGA evolving its in-store programs to align with online expectations and behaviors?From your experience, what's the most overlooked opportunity for brand and shopper marketing leaders to create more profitable customer relationships in today's CPG-retail ecosystem?

What if the key to calming autoimmunity isn't stronger suppression, but a clearer conversation between your gut and your immune system?In this episode, we sit down with integrative and functional medicine nutritionist Vanessa Vanderhoek to explore how microbiome shifts, barrier breakdown, and nervous system stress converge into autoimmune flares,  and how the GI-MAP can transform complexity into a clear, safe plan. We unpack the clinical significance of dysbiosis patterns such as Klebsiella and Prevotella, the risks signalled by depleted keystone species like Faecalibacterium prausnitzii, and what these patterns reveal about conditions including rheumatoid arthritis, lupus, MS, and juvenile arthritis. You'll learn how to interpret zonulin for leaky gut, use secretory IgA highs and lows as action points, and rely on calprotectin and occult blood as decisive markers for medical referral.Vanessa brings the science to life with real cases: an ulcerative colitis patient who avoided bowel resection by making one well-timed dietary shift; a rare and painful skin condition that settled once triggers were removed and the mucosa repaired; and a case of severe bloating that revealed the early clues of scleroderma, guiding faster diagnosis and a clear path forward. Throughout, we highlight the principles of precision and pacing, building plans that align with a client's readiness, capacity, and budget so meaningful change actually sticks.We also address the often-overlooked driver: vagus nerve dysfunction and chronic stress. When the sympathetic system takes over, digestion stalls, sIgA drops, and tolerance erodes. Vanessa walks us through the simple rituals that restore regulation, sitting to eat, slower chewing, pre-meal breathing, and the nutrients that rebuild the mucosal barrier, including vitamins A, D and E, and zinc. Safety threads through the entire conversation: co-managing with GPs, repeating calprotectin when indicated, and cross-checking protocols with immunosuppressant medications.If you're looking for fewer flares, shorter recovery times, and more agency in autoimmune care, this episode gives you a grounded, clinically relevant roadmap. Subscribe, share with a practitioner friend, and let us know your biggest takeaway.Connect Vanessa:Vanessa's podcast Thrive Forward: https://podcasts.apple.com/au/podcast/the-thrive-forward-podcast/id1806055391 YoutubeShownotes and references are available on the Designs for Health websiteRegister as a Designs for Health Practitioner and discover quality practitioner- only supplements at www.designsforhealth.com.au Follow us on Socials Instagram: Designsforhealthaus Facebook: Designsforhealthaus DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

A nefropatia por IgA está entre as glomerulopatias mais comuns na prática clínica e continua repleta de dúvidas: quando biopsiar? É hora de iniciar imunossupressão? Quanto tempo manter o tratamento?Neste episódio especial, gravado durante o 2º Nefro Centro Oeste, conversamos com o Dr. Juan Mejia-Vilet (México), nefrologista e membro do staff do KDIGO de Glomerulopatia.Abordamos questões que todo nefrologista enfrenta:Devemos mesmo já biopsiar pacientes com proteinúria de 500–600 mg/dia?Hematúria é marcador de atividade?Como distinguir inflamação de dano crônico?6-9 meses de imunossupressão é suficiente ?Qual o futuro da IgA com terapias anti-linfócitos B?

Maude Lanteigne, c'est une vraie tornade d'énergie et de passion! Fière de voir l'évolution du sport féminin et la place grandissante des femmes dans le sport, Maude partage son parcours, ce qui l'anime et sa vision du sport.Animatrice fonceuse et authentique, elle n'était pas prédestinée à ce métier, et pourtant aujourd'hui, elle est une voix bien connue des Québécois.Sa relation avec les Lions de Trois-Rivières reste spéciale : c'est là qu'elle a commencé et où elle a découvert sa passion pour animer et connecter avec les foules. Depuis, elle a conquis les grandes scènes : F1 Montréal, Alouettes, Alliance, Victoire, Canadiens et Roses.Dans cet épisode du balado Isa, Femme de sports, présenté par IGA, Maude nous ouvre les coulisses de sa vie professionnelle… et personnelle. Elle nous partage:Sa passion pour le sport et son expérience unique avec la F1 Montréal, sa “NHL à elle”Sa relation spéciale avec les Lions et ce qui rend cette équipe si unique pour elleComment elle vit l'évolution du sport féminin dans les estrades avec les fansL'importance du courage d'oser se tromper et ce que ça lui a apprisSon moment le plus marquant : sa première fois au Centre BellCe qui la fait rire, vibrer et continuer à avancerUne conversation vibrante qui met en lumière l'humain derrière le sport et la force d'une femme qui ose.️ Dis-moi ce qui t'a le plus marqué dans la discussion avec Maude!Le balado Isa, femme de sports est diffusé les jeudis 16h30 à TVA Sports.

In this transformative episode, I sit down with my own teacher and mentor, Dr. Karen Parker, to explore the fascinating world of Quantum Human Design and how our stories literally shape our biology. Dr. Parker is a pioneer who studied with the founder of traditional Human Design and has taken the system to its next evolution—helping people not just understand who they're not, but consciously create who they want to become.  What You'll Discover  Understanding Quantum Human Design  The difference between traditional Human Design and Quantum Human Design  How Human Design synthesizes Eastern and Western astrology, the Chinese I Ching, Hindu chakra system, and Judaic Kabbalah  Why getting back into your body is essential for authentic decision-making  The evolution from learning "who you're not" to consciously creating "who you choose to become"  The Biology of Our Stories  How victim-based narratives actually lower immune response (IgA levels)  The physiological changes that occur when you reframe your story  Why optimists live longer and have longer telomeres  The connection between storytelling and post-traumatic growth  Moving Beyond Survival  Why defining ourselves as "survivors" keeps us stuck at a minimal baseline  The danger of stopping your story at the cliffhanger  How to move from surviving to thriving through the redemption arc  The Stage 3 trap: how repeating our betrayal story keeps us stuck  The Story Lab Process  A creative, fun approach to rewriting your narrative (yes, it can be enjoyable!)  Using creative writing to bypass logic and reasoning patterns  Why taking your story "out of time" creates powerful shifts  Real-life example: How one woman transformed from victim to empowered protector  Key Takeaways  Your story creates your identity, and your identity calls in experiences that validate it. Breaking this cycle requires conscious narrative reframing.  Healing doesn't have to be a crisis. The Story Lab process proves that transformation can actually be creative, playful, and fun.  Check in with your body. After sharing your betrayal story, does your body feel light, open, and expansive? Or heavy and contracted? Your body knows the truth.  The power of the redemption arc. Your story doesn't end at the betrayal—that's just the catalyst. The real story is what happens next and who you become.  Powerful Exercise to Try  Draw a horizontal line across a piece of paper. The left represents your birth, the right represents where you are now. Mark all the significant experiences in your life along this timeline. Then ask yourself: "Did I stop my story at the cliffhanger, or have I defined myself by what happened next?"  If you're still hanging at the cliffhanger, you deserve better than that.  About Dr. Karen Parker  Dr. Karen Parker holds a PhD in transpersonal psychology and is the creator of Quantum Human Design. She studied directly with the founder of traditional Human Design and spent three years in a Sound Lab testing the frequency of vocabulary to create an entirely new system that helps people consciously write their sovereign story. She's also the author of multiple books, including Quantum Wellness, which walks readers through the Story Lab process.  Connect with Dr. Karen Parker  Website: QuantumHumanDesign.com  Instagram & Facebook: @DrKarenParker22  Book: Quantum Wellness (available at major online retailers)  Stay in Touch  The PBT Institute: https://thepbtinstitute.com   My Personal Connection  As a 4/6 Manifesting Generator (Time Bender) myself, studying with Dr. Karen was life-changing. Learning about the triphasic life cycle of the 4/6 profile helped me understand why my life crashed and burned at exactly age 50—and why that was actually the beginning of my true purpose work. The concept of "finding shortcuts" as a Manifesting Generator perfectly explains why the five stages of Post Betrayal Transformation showed up in my research—it was THE shortcut to healing! 

Celiac disease affects between one and two percent of Canadians, yet many patients wait years before receiving a clear diagnosis. On this episode of the CMAJ Podcast, the hosts speak with two contributors to the CMAJ review article Diagnosis and management of celiac disease about the condition's diverse clinical presentations, appropriate testing strategies, and the practical realities of long-term dietary management.Jedid-Jah Blom, a registered dietitian at the McMaster Celiac Disease Clinic and researcher at the Farncombe Family Digestive Health Research Unit at McMaster University, shares her own experience being diagnosed and living with celiac. She explains how patients must identify hidden gluten sources in ingredients like dextrin and malt, and why cornmeal or corn flour products may be contaminated. Blom outlines the risks of cross-contamination and dining out challenges, emphasizing whole gluten-free grains over processed products that lack fortification.Dr. Maria Ines Pinto-Sánchez, a gastroenterologist at Hamilton Health Sciences and director of the Celiac Clinic at McMaster University, explains why celiac is called a chameleon disease. She notes that about 30 percent of patients present with gastrointestinal symptoms, while others may have brain fog, fatigue, or anemia. She describes how TTG antibodies plus total IgA are used for screening, with positive results requiring endoscopy and biopsies for confirmation. Dr. Pinto-Sánchez emphasizes that patients should not start a gluten-free diet before testing. She discusses ongoing monitoring including TTG levels, bone density, and nutrient deficiencies.For physicians, the discussion highlights the need for a low threshold when testing TTG antibodies in patients with unexplained fatigue, brain fog, or gastrointestinal symptoms. Both guests stress the importance of completing diagnostic testing before patients begin a gluten-free diet and arranging early dietitian referral.Comments or questions? Text us.Join us as we explore medical solutions that address the urgent need to change healthcare. Reach out to us about this or any episode you hear. Or tell us about something you'd like to hear on the leading Canadian medical podcast.You can find Blair and Mojola on X @BlairBigham and @DrmojolaomoleX (in English): @CMAJ X (en français): @JAMC FacebookInstagram: @CMAJ.ca The CMAJ Podcast is produced by PodCraft Productions

The FiltrateJoel Topf‍ ‍@kidneyboy.bsky.social‬ (COI)Sophia Ambruso @sophia-kidney.bsky.socialSwapnil Hiremath @hswapnil.medsky.social and on LinkedInSpecial Guests Jonathan Barratt Professor of Renal Medicine, University of Leicester Google Scholar (COI: all the companies)Editing and Show Notes byNayan Arora @captainchloride.bsky.socialThe Kidney Connection written and performed by Tim YauShow NotesProteinuria Reduction as a Surrogate End Point in Trials of IgA Nephropathy (Aliza Thompson, 2019 PubMed)The number, quality, and coverage of randomized controlled trials in nephrology (PubMed 2004)Updated here (PubMed | NephJC discussion)A Randomized, Controlled Trial of Rituximab in IgA Nephropathy with Proteinuria and Renal Dysfunction (PubMed 2017)BLISS Belimumab in lupus nephritis (NephJC | PubMed) The Phase 2 trial of atacicept A phase 2b, randomized, double-blind, placebo-controlled, clinical trial of atacicept for treatment of IgA nephropathy (PubMed)The phase 3 trial of atacicept, the subject of this podcast A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy (PubMed | NephJC)Christos' Bluesky post:https://bsky.app/profile/christosargyrop.bsky.social/post/3m5bsujwg3s2q The use of Gd-IgA1 in the Testing Trial Role of Systemic Glucocorticoids in Reducing IgA and Galactose-Deficient IgA1 Levels in IgA Nephropathy (PubMed)If you can't get enough Jon Barratt, take a look at his grand rounds at The University of Ottawa. Updates to the KDIGO Guidelines for the treatment of IgA nephropathy, with Prof Jonathan Barratt (YouTube)Tubular SecretionSwapnil Hiremath Pluribus on Apple TV (Wikipedia)Jon Barratt Lynyrd Skynyrd (Wikipedia) Slow Horses (Wikipedia) on AppleTVJoel Topf the new ASN

Send us a textGood morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve deep into a series of transformative events that underscore the dynamic nature of our industry, where scientific innovation meets regulatory evolution and market adaptation.We begin with significant regulatory news from Medicare, which recently announced price reductions for 15 prescription drugs, including Novo Nordisk's semaglutide products, Ozempic and Wegovy. This initiative is part of the Inflation Reduction Act aimed at making essential medications more affordable. By potentially increasing accessibility to these treatments, this move highlights a growing trend towards cost containment in drug pricing within the U.S. healthcare system. It reflects a broader effort to ensure that life-saving treatments remain within reach for more patients, emphasizing the need for balance between innovation and affordability.Turning to approvals, Otsuka has secured FDA clearance for Voyxact, a first-in-class treatment targeting IgA nephropathy (IgAN). This positions Otsuka in an increasingly competitive market space populated by major players like Novartis and Vertex. The entry of Voyxact could pave the way for innovative therapeutics in kidney diseases, offering new hope to patients who have had limited treatment options until now.On the other side of the Atlantic, French authorities have conducted a raid on Sanofi's headquarters as part of a tax fraud investigation. This development sheds light on ongoing scrutiny in the pharmaceutical sector regarding financial practices and regulatory compliance. Such investigations can have far-reaching implications on corporate governance and transparency, reminding us of the importance of ethical practices in maintaining industry trust.Novo Nordisk has strategically used its FDA national priority voucher to expedite the review process for a high-dose formulation of Wegovy. This move underscores the importance of regulatory incentives in accelerating drug development timelines, allowing for quicker patient access to potentially life-changing therapies. It's a testament to how strategic navigation through regulatory pathways can significantly impact drug availability.In clinical trials, Sarepta Therapeutics received FDA clearance to conduct a study combining its gene therapy Elevidys with sirolimus in patients with Duchenne muscular dystrophy. The study aims to address liver safety issues associated with Elevidys, which had led to previous label restrictions. This reflects the industry's commitment to enhancing therapeutic safety profiles while expanding treatment indications.In oncology advancements, AstraZeneca's Imfinzi received FDA approval for use in early-stage stomach cancer, marking its third perioperative indication. This approval underscores the expanding role of immunotherapy across various cancer types and stages, offering new treatment paradigms that could improve surgical outcomes and long-term patient survival.Despite these advances, there is skepticism regarding artificial intelligence's role in regulatory compliance submissions among pharmaceutical professionals. A survey reveals that 65% express distrust towards AI-generated outputs, highlighting challenges that AI technologies face in gaining acceptance within highly regulated environments such as pharmaceuticals. However, federal recommendations to revamp U.S. biotechnology research emphasize incorporating AI into scientific processes to maintain global competitiveness. This call reflects concerns over potential declines in innovation leadership and underscores the need for strategic investment in research infrastructure.In antitrust news, the Federal Trade Commission (FTC) outlined its case agaiSupport the show

The SERMI scheme is finally coming to the UK, so what's it all about? The IGA's Jon Douglass tells PMM everything garages need to know about how it can help your business. The scheme enables garages to access security information from the vehicle manufacturers via a single portal. Will you be signing up?This episode is sponsored by Wynn's

La seule Québécoise repêchée dans la LPHF : Maya Labad se confie! Choisie en 5e ronde par la Victoire de Montréal, elle vit des moments uniques. Lors de l'enregistrement, elle ne savait pas encore qu'elle signerait un contrat standard avec l'organisation. Dans cet épisode du balado Isa, Femme de sports, présenté par IGA, Maya se confie avec sincérité, entre pression, ambition et grandes émotions. Elle nous raconte : Le moment magique où elle a entendu son nom au repêchagePourquoi son style de jeu est comparé à celui de Caroline Ouellette Ce qui nourrit sa passion pour le hockey Pourquoi elle a choisi d'étudier en criminologie Les valeurs et les inspirations qui la guident Sa définition personnelle du succès Elle revient aussi sur sa relation avec son cousin Tomas Lavoie, repêché dans la LNH par le Mammouth de l'Utah, et sur l'impact des femmes de sa famille dans son parcours. Et on termine avec nos fameux Tirs de barrage : entre Poulin et Ouellette… qui choisira-t-elle ? Une conversation authentique avec une athlète à suivre de très près.

Ancien joueur des Canadiens, aujourd'hui commentateur et chroniqueur hockey, Steve Bégin se livre sans filtre dans ce nouvel épisode du balado Isa, Femme de sports, présenté par IGA.Toujours intense, il met son énergie au service de la relève, convaincu que le développement et la santé mentale sont l'essence même du sport. Steve, c'est un gars de cœur, de courage et de conviction, aussi drôle que authentique.Dans cet épisode, Steve :Partage sa vision du hockey d'hier à aujourd'huiRaconte ce qui nourrit sa passion pour le sportSe prononce sur la santé du sport, du hockeyExplique son rôle d'ambassadeur pour l'application Athlete-XFait une révélation choc sur les médias sportifsValorise le sport féminin et ses modèles inspirantsUn échange vrai, drôle et humain, comme dans un vestiaire où on dit les vraies affaires.Tu m'en donneras des nouvelles!?!Suis-moi sur mes médias sociaux pour plus de contenu:Facebook : Isa, Femme de sports Instagram : @isa.femme.de.sports X : @Isabelleethier Pour écouter Steve Begin sur le balado Femme d'Hockey, c'est par ici

In this powerful episode of Diary of a Kidney Warrior Podcast, Dee sits down with Louise, a kidney warrior whose journey with IgA nephropathy spans over 30 years – from diagnosis in her early 20s, to pregnancy complications and heartbreaking baby loss, to finally receiving her life-changing kidney transplant, lovingly named “Katie the Kidney.”   Louise shares how her kidney disease was first discovered during pregnancy, the devastating loss of her son, and how for decades she coped by “putting everything in a box” and carrying on with life. She talks about living abroad with only 22% kidney function, unknowingly walking 20K with undiagnosed angina, and why kidney disease can be such a silent condition.   In an emotional and hope-filled conversation, Louise describes the moment she received “the call” for transplant, watching her donor kidney arrive in a cooler from Edinburgh, and being wheeled to theatre with Katie the Kidney on the end of her bed. She also opens up about the emotional healing that came with kidney failure – exploring trapped emotions, trauma, faith, and learning to truly take responsibility for her health and wellbeing.   If you're newly diagnosed, living with chronic kidney disease (CKD), resisting the idea of dialysis or transplant, or struggling emotionally with your diagnosis, this episode will give you hope, validation and practical encouragement.   In this episode, we discuss: •Louise's first signs of kidney disease and IgA nephropathy diagnosis •Pregnancy, kidney disease and the loss of her baby son •Living 30+ years with CKD and feeling “fine” at 22% kidney function •Discovering angina during transplant workup •Getting the call and meeting “Katie the Kidney” •How transplant changed her energy, skin, and brain fog •The emotional side of kidney disease: grief, trauma, “putting it in a box” •Why acknowledging your diagnosis and caring for your mental health is essential •Louise's advice for anyone newly diagnosed or scared of dialysis / transplant   You are not alone. Kidney disease is not the end – it's part of your story, not your identity.    

"Life has not become simpler and easier. It's become more complex. Success requires acknowledging this complexity early and building flexibility into every aspect of the business model.”Renée Aguiar-Lucander is the CEO of Hansa Biopharma, appointed in April 2025. Renée brings rich expertise from seven years leading Calliditas Therapeutics through a dual NASDAQ listing and the first approved drug for IgA nephropathy, plus extensive healthcare investment experience at Omega Funds and 3i Group.Speaking to PharmaSource at Nordic Life Science Days (NLSDays), Renée shares candid insights on the investment climate that's reshaped biotech over the past few years, the structural challenges facing European companies, and what early-stage biotechs need to focus on to survive an increasingly selective funding environment.Read more.

Conheça os principais avanços da nefrologia apresentados no Kidney Week 2025, o maior congresso de nefrologia do mundo.Nesta PARTE 1, discutimos:✅ Podemos curar as doenças renais? "Yes, we can"✅ Análises atualizadas sobre o impacto dos SGLT2i independentemente da albuminúria✅ Evidências para uso de SGLT2i em DM1, DRC avançada, diálise e transplante✅ As novidades da Nefropatia por IgA com foco em terapias alvo✅ A transição para uma nefrologia baseada em mecanismos, que está remodelando a prática clínicaFique atento: em breve publicaremos a Parte 2 com mais destaques do congresso.------------------------------------------

Who Killed Sarah Pryor? I want to thank a listener for suggesting this story. I have done episodes on the case of Molly Bish and Holly Pirrainen, and the listener suggested I look into the case of Sarah Pryor. Another case connected loosely to the Pryor case is that of 16-year-old Cathy Malcolmson. Cathy was working at the IGA supermarket when she was abducted on her way home from work. The listener, who is from the Massachusetts area where these abductions took place, said there had been some talk that Sarah's case may also be connected to Molly and Holly's cases. I decided to look into the Pryor mystery and was surprised by what I found. One of the similarities I began to see was the area's geography and how close these incidents took place to one another. Sarah was taken an hour from where Holly went missing, but all three of these cases occurred just off the Massachusetts Turnpike. It may be a stretch to think these cases could be connected, but it doesn't mean the idea should be discounted. Some books and documentaries talk about how the construction of the interstate enabled a new type of killer. Sources: ⁠Bella English⁠ ⁠Boston Globe⁠ ⁠Southcoasttoday.com⁠ ⁠Eileen Prose- YouTube⁠ ⁠Metro West Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is sponsored by Nexis. Visit nexis-secure.com/idac to learn more.In this sponsored episode of *Identity at the Center*, host Jim McDonald sits down with Dr. Heiko Klarl, CEO of Nexis, to explore how the company is advancing authorization governance for modern enterprises. Dr. Klarl explains how Nexis builds visibility and control across fragmented identity landscapes and why “better together” is the right strategy for enterprises with multiple IAM systems.They discuss the emerging Identity Visibility and Intelligence Platform (IVIP) category, the value of automation and remediation in governance, Nexis's unique “health check” service, and their ISPM capability that helps clients identify unnecessary access—and even save on software licensing.Learn how Nexis integrates with IGA and PAM tools, streamlines application onboarding, and helps customers measure the real business impact of their identity programs.Connect with Heiko: https://www.linkedin.com/in/heiko-klarl/More about Nexis: https://nexis-secure.com/idacConnect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at idacpodcast.comChapters00:00 Introduction and Sponsor Message00:42 Meet Dr. Heiko Klarl, CEO of Nexis01:29 Dr. Klarl's Journey into Identity and Access Management03:09 What Does Nexis Do?05:00 Challenges in Authorization Governance06:43 The Importance of Visibility in Identity Systems08:23 Nexis' Role in Enhancing Existing IAM Investments10:05 The Concept of IVIP and Its Relevance21:48 Nexis Platform Capabilities23:24 The Health Check: A Deep Dive27:22 Understanding Health Check Costs28:27 Exploring ISPM and License Management32:09 How Nexis Integrates with IGA Systems34:11 Application Onboarding and Compliance36:38 Measuring Value and Success with Nexis43:10 Global Reach and Market Focus45:02 Connecting at Conferences46:49 Visiting Germany: Recommendations and Insights50:17 Final Thoughts and ResourcesKeywordsIDAC, Identity at the Center, Jim McDonald, Jeff Steadman, Dr. Heiko Klarl, Nexis, Nexis Secure, NEXIS 4, authorization governance, role mining, role management, IGA, IAM, IVIP, Identity Visibility and Intelligence Platform, access certification, remediation automation, health check, ISPM, Identity Security Posture Management, license management, enterprise identity, compliance, visibility, identity governance, access review, Gartner IAM, EIC, KuppingerCole

In this episode of Tea with Dr D, host James Q. Del Rosso, DO, is joined by Christopher Bunick, MD, PhD, and later Lisa Swanson, MD, for a deep look at phosphodiesterase-4 (PDE4) inhibition in dermatology, with a special focus on topical roflumilast.  Dr Bunick opens with a primer on the science of PDE4, an enzyme that degrades cyclic AMP (cAMP), an intracellular messenger that regulates anti-inflammatory pathways. In conditions such as atopic dermatitis (AD) and psoriasis, overactive PDE4 leads to reduced cAMP and amplified inflammation. By “gumming up” PDE4, roflumilast restores a more balanced, anti-inflammatory state.  He explains why PDE4 inhibition is relevant across multiple inflammatory pathways, including Th1, Th2, and Th17, and why roflumilast has demonstrated stronger efficacy than earlier inhibitors like crisaborole. Molecularly, roflumilast mimics cyclic AMP's binding to PDE4 across 3 key sites, producing far tighter binding than apremilast and crisaborole, which translates to superior clinical potency.  Dr Bunick illustrates this with a case of palmoplantar pustular psoriasis that cleared dramatically within 8 weeks on topical roflumilast after multiple biologic and corticosteroid failures, highlighting its durability and barrier-restoring properties. He and Dr Del Rosso contrast this with the limitations of chronic steroid use, noting that roflumilast supports long-term control without barrier compromise.  The discussion also touches on vitiligo, where Dr Bunick shares an early case of repigmentation following roflumilast treatment, suggesting possible cAMP-mediated stimulation of melanogenesis. They highlight the molecule's innovative aqueous-based formulation, optimized for skin-compatible pH and excellent tolerability.  In Part 2, Dr Swanson joins to discuss pediatric use. She reviews the 0.15% cream for AD in patients ≥6 years and the 0.05% cream for ages 2–5, both once-daily, steroid-free options that minimize burning and stinging compared with earlier PDE4 inhibitors. They review clinical data that demonstrate rapid itch relief, strong efficacy across IGA and EASI end points, and sustained control with twice-weekly maintenance.  Tune in to hear how PDE4 inhibition, and particularly topical roflumilast, is redefining nonsteroidal therapy across age groups and disease states in dermatology. 

What if adult acne isn't hormonal after all, but an inflammatory signal from the gut asking for help?In this thought-provoking episode, naturopath Asha Evertsz unpacks the gut–skin–brain axis and reveals why most adult acne is less about hormones and more about systemic inflammation, microbial imbalance, and stress. Drawing on years of clinical experience treating complex female acne, Asha reframes the condition as a terrain issue, not a topical one, where digestion, bile flow, and microbial diversity determine how the skin behaves.You'll hear how chronic stress, impaired digestion, and microbiome disruption from antibiotics, the pill, and Roaccutane alter immune pathways and ignite the mTOR signalling cascade that fuels breakouts. Asha walks through the stool markers that matter, including secretory IgA, zonulin, SCFAs, and Akkermansia, and explains the overlooked roles of bile, stomach acid, and pancreatic enzymes, her “guardians of the gut.” She demystifies the H. pylori connection, showing how low stomach acid and disrupted FOXO1 and IGF-1 pathways link directly to acne through poor absorption, excess sebum, and inflammation.From there, we get practical. Asha outlines her phased gut-repair framework: fortifying mucosal defences, feeding the microbiome with fibre and polyphenols, introducing strain-specific probiotics, and only then layering in antimicrobials like berberine, a clever mTOR modulator. She shares clinical pearls on using bovine immunoglobulins to rebuild IgA and barrier function, timing omega-3s once bile flow is restored, and using zeolite, curcumin, and green tea to bind and calm the system during detox. From the outside in, she explains how corneotherapy protects the skin's acid mantle and microbiome with topical pre-, pro-, and postbiotics, ditching harsh actives that create “leaky skin.”Whether you're a practitioner ready to move beyond surface-level acne care or a clinician refining your gut-first protocols, this conversation offers a test-led roadmap for rebuilding both inner and outer barriers, turning chronic flare-ups into calm, resilient skin.Connect with Asha: Acne Naturopath | Asha Evertsz | HomeShownotes and references are available on the Designs for Health websiteRegister as a Designs for Health Practitioner and discover quality practitioner- only supplements at www.designsforhealth.com.au Follow us on Socials Instagram: Designsforhealthaus Facebook: Designsforhealthaus DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

In this powerful Kidney Warrior Story, host Dee sits down with Tony to unpack a decade-spanning journey through chronic kidney disease (CKD)—from a shock Stage 4 diagnosis of IgA Nephropathy (IgAN) to Stage 5 kidney failure, peritoneal dialysis (PD) with brutal drain pain, a transition to haemodialysis (HD), line infection and coma, the courage to self-needle with a fistula, and ultimately the life-changing gift of a kidney transplant.   Tony shares the practical and emotional realities few hear about: choosing PD vs HD, APD (overnight machine) vs manual gravity bags, buttonhole vs rope-ladder needling, home haemodialysis training, fluid management, and rebuilding confidence after hospital trauma. He explains how movement and sport (from 5K Parkruns to half marathons) helped his mental health on dialysis—and how he kept going after FIVE “dry-run” transplant calls before finally receiving his match.   Post-transplant, Tony competed at the Transplant Games (bronze in cycling!), then faced a sudden cycling accident with a broken talus—and still came back stronger with kidney function over 90%. Tony's message? You're not alone. With support, information, and small, consistent steps, more is possible than you think.   WHAT YOU'LL HEAR • Early signs missed: high blood pressure and “white coat” assumptions  • Stage 4 to Stage 5 CKD: understanding IgA Nephropathy and next steps  • Peritoneal Dialysis (PD): APD vs gravity bags, real talk on drain pain  • Haemodialysis (HD): line infection → coma, then fistula and self-needling  • Buttonhole vs rope-ladder: how Tony overcame needle phobia  • Home HD routine + exercising safely on dialysis (5K to half marathons)  • Five transplant calls that didn't happen—coping tools that helped  • The call that changed everything: consent, surgery, waking the kidney  • Transplant Games success—and recovery after a serious cycling crash  • Mental health: therapy, peer groups, and why talking saves lives  • Practical tips: fluid limits, pacing activity, and building back slowly  • Community resources: Kidney Care UK, young adult kidney groups   KEY TAKEAWAYS • Movement is medicine—start with what you can manage (even 100 metres).  • Your effort matters—even when decline happens, you may be delaying harm.  • Build your circle: family, peers, clinicians, therapists, Kidney Care UK.  • Advocacy counts: read clinic posters, join groups, ask questions.  • Mindset + support = progress. Small daily actions add up.   If you're newly diagnosed or supporting someone with CKD, browse our back catalogue for in-depth episodes on PD, HD, transplant prep, and mental health.   Follow Diary of a Kidney Warrior:  

Send us a textCan one AI system learn from every organ — and teach us something new about all of them?In this edition of DigiPath Digest #31, I explore how artificial intelligence is transforming pathology across multiple organ systems, revealing connections that help us diagnose faster, more consistently, and more accurately than ever before.From glomerulonephritis to hepatocellular carcinoma, AI is no longer confined to a single specialty — it's becoming the connective tissue between them.What's Inside:1️⃣ AI for Bladder Cancer Classification We begin with a multicenter study validating AI models for urothelial neoplasm classification using over 12,000 whole-slide images. Both CNNs and transformer models achieved high accuracy (AUC 0.983, F1 score 0.9). I discuss why the F1 score matters — and what it tells us about model balance between sensitivity and specificity.2️⃣ AI in Colorectal Cancer Care Next, we explore multimodal AI — integrating histopathology, radiology, genomics, and blood markers to modernize colorectal cancer workflows. AI now helps detect adenomas, infer microsatellite instability (MSI) from H&E slides, and predict treatment outcomes. I highlight the critical need for external validation, interpretability, and governance as AI enters clinical use.3️⃣ AI for Glomerular Nephritis Diagnosis A deep learning model trained on over 100,000 kidney biopsy images identified four nephritis types — FSGS, IgA, MN, and MCD — with over 85% accuracy. This technology could ease workloads and improve turnaround time in renal pathology. Still, I share why AI support may feel both empowering and unsettling for many pathologists.4️⃣ AI in Liver Disease (MASLD & HCC) AI is advancing noninvasive fibrosis staging and risk prediction in liver pathology. From large consortia like NIMBLE and LITMUS to predictive models for HCC therapy response, AI is moving us closer to precision hepatology. I also discuss the challenge of translating these tools from research to regulatory approval.5️⃣ Lightweight AI for Domain Generalization Finally, we look at one of pathology AI's biggest challenges: domain shift — when a model trained on one scanner or staining style performs poorly elsewhere. The new Histolite framework shows how lightweight, self-supervised models can generalize across data sources — trading some accuracy for reliability in real-world use.My TakeawayAcross every study, a single message stands out: AI isn't replacing pathologists — it's amplifying our vision. By connecting kidney, colon, liver, and bladder insights, AI is teaching us that medicine works best when it learns across boundaries.Episode HighlightsBladder cancer AI validation (06:41)Multimodal colorectal AI (12:38)Glomerular nephritis deep learning (19:29)AI in liver pathology (29:55)Domain shift & Histolite framework (38:17)Halloween wrap-up + SITC preview (46:18)Join me next time for updates from the SITC 2025 Conference, where I'll be live at Booth 415 with Hamamatsu and Biocare, discussing how AI and spatial biology are converging to drive clinical utility.#DigitalPathology #AIinHealthcare #ComputationalPathology #CancerDiagnostics #LiverPathology #RenalPathology #FutureOfMedicine #DigiPathDigestSupport the showGet the "Digital Pathology 101" FREE E-book and join us!

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into some of the most significant shifts and strategies shaping our industry.Novartis's acquisition of Avidity Biosciences for a staggering $12 billion marks a pivotal moment in the pharmaceutical landscape this year. With this acquisition, Novartis underscores its commitment to bolstering its neuromuscular disease pipeline. Avidity Biosciences has made a name for itself with its cutting-edge RNA therapeutic technologies, particularly its Antibody Oligonucleotide Conjugates (AOCs). This platform uniquely combines monoclonal antibodies with oligonucleotides, enhancing precision in targeting specific cell types. The integration of Avidity's technology into Novartis's research efforts could accelerate the development of new therapies, potentially transforming patient care with more effective and targeted treatment options. This move not only highlights the industry's focus on specialized therapeutic areas but also anticipates future advances in RNA therapeutics, extending beyond neuromuscular disorders to areas like oncology.In a similar vein, the FDA has shown its willingness to reconsider drugs that previously faced setbacks. GSK's Blenrep has made a return to the U.S. market after receiving approval for treating certain myeloma patients. This approval is particularly noteworthy given the drug's earlier negative advisory committee vote and postponed decision. It marks a significant rebound for GSK's oncology portfolio and reflects the FDA's dynamic approach towards drugs that show potential in specific therapeutic combinations.Meanwhile, Sanofi continues to make waves with Dupixent, achieving over €4 billion in quarterly sales due to its expanded indications. This success contrasts with a decline in Sanofi's vaccine sales, demonstrating shifting dynamics within pharmaceutical portfolios where biologics and specialty drugs are increasingly pivotal. Sanofi's recent financial report highlighted a notable 17% drop in vaccine sales due to reduced demand and pricing challenges in Europe. In response, companies must navigate fluctuating public health demands and economic pressures effectively.On the global stage, efforts to make transformative therapies like Vertex's Trikafta more accessible are gaining momentum through innovative trade-policy workarounds. A buyers club aims to introduce a lower-cost alternative produced by Bangladesh's Beximco, highlighting ongoing challenges and creative strategies in global drug accessibility.Roche's expansion through Chugai's $200 million M&A deal for an IgA nephropathy asset underscores the strategic importance of regional markets in driving growth. Similarly, Lonza's acquisition of a California biologics site aligns with its goals to meet increasing biomanufacturing demands.The industry is also adapting to technological advancements, with AI integration into life sciences commercialization being touted as a frontier for growth. Despite this potential, many organizations remain unprepared to harness AI fully. Leading companies embedding AI solutions aim for measurable outcomes that could significantly drive strategic decision-making and operational efficiencies.Eli Lilly's acquisition of Adverum Biotechnologies aligns with its strategic interests in gene therapy, focusing on promising therapeutic programs that address unmet medical needs. This acquisition centers around Ixo-vec for wet age-related macular degeneration (AMD), highlighting broader industry trends towards investing heavily in innovative therapies that address unmet needs.Conversely, Sanofi's halt on an RSV vaccine development highlights the inherent risks in vaccine development pipelines. Meanwhile, Regeneron's decision to discontinue a CAR T candidate acquired from 2seventy bio showcases ongoing reassessment witSupport the show

Welcome to HCPLive's 5 Stories in Under 5—your quick, must-know recap of the top 5 healthcare stories from the past week, all in under 5 minutes. Stay informed, stay ahead, and let's dive into the latest updates impacting clinicians and healthcare providers like you! Interested in a more traditional, text rundown? Check out the HCPFive! Top 5 Healthcare Headlines for October 12-18, 2025: 1. FDA Accepts Inhaled Insulin (Afrezza) sBLA for Pediatric Diabetes The FDA accepted MannKind's sBLA for Afrezza inhaled insulin to expand its use to children and adolescents with type 1 or type 2 diabetes. 2. FDA Approves Updated Indication for Upadacitinib (Rinvoq) in IBD The FDA broadened upadacitinib's indication to allow use in ulcerative colitis and Crohn disease when tumor necrosis factor blockers are not clinically appropriate. 3. FDA Clears First Blood Test to Rule Out Alzheimer-Related Amyloid Pathology The FDA cleared Elecsys pTau181 as the first blood test to help rule out Alzheimer-related amyloid pathology in older adults with cognitive symptoms. 4. Digital Therapeutic Reduces Negative Symptoms of Schizophrenia in Phase 3 Trial A phase 3 study showed a prescription digital therapeutic significantly reduced negative symptoms in schizophrenia when used alongside antipsychotic therapy. 5. APPLAUSE-IgAN: Iptacopan (Fabhalta) Meets eGFR Decline Primary Endpoint Iptacopan demonstrated meaningful efficacy in slowing kidney function decline in adults with IgA nephropathy, supporting future regulatory submissions.

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're delving into a series of fascinating updates that underscore a period of significant scientific advancement, strategic partnerships, and regulatory developments in the industry.Starting with Dianthus Therapeutics, which has taken a bold step by investing up to $1 billion to license a bifunctional fusion protein from Nanjing Leads Biolabs. This protein targets autoimmune disorders, a field of immense interest due to the unmet medical needs and potential for breakthrough treatments. Such substantial financial commitments highlight the ongoing trend in the biotech sector towards innovative therapies for autoimmune diseases. In parallel, Sanofi has secured a $500 million agreement with Evoq Therapeutics, continuing its strategic focus on next-generation autoimmune technologies. This partnership aligns with Sanofi's broader strategy to leverage cutting-edge science in managing autoimmune conditions more effectively. Sanofi's engagement with Evoq Therapeutics stands out as a significant step forward in conquering autoimmune diseases through nanodisc technology designed to facilitate the development of curative treatments for disorders like celiac disease and type 1 diabetes. This collaboration reflects a growing trend among pharmaceutical giants investing in advanced biotechnologies that promise transformative impacts on disease management and patient care.Meanwhile, AstraZeneca's renewed collaboration with Immunai, valued at $85 million, seeks to enhance therapies for inflammatory bowel disease through artificial intelligence. This collaboration is part of a wider industry movement towards utilizing AI in drug discovery and development, particularly for complex diseases like IBD. AI's ability to process large datasets and identify potential therapeutic targets faster and more accurately is revolutionizing how companies approach drug development.In clinical trial news, Praxis Precision Medicines has reported positive Phase 3 results for ulixacaltamide in treating essential tremor. This outcome reverses prior concerns from interim analyses and illustrates the persistent innovation in neurological disorder treatments. Similarly, AiCuris has announced successful results from its Phase 3 trial of pritelivir for refractory herpes simplex virus infections in immunocompromised patients. This success paves the way for an FDA filing, demonstrating ongoing progress in antiviral therapy development.Novartis is also making strides with favorable outcomes from its Phase 3 trial of fabhalta for IgA nephropathy. As a complement factor B inhibitor, fabhalta has shown efficacy in slowing kidney function decline, which may lead to a new standard of care for this chronic kidney disease. Novartis plans to file these findings with regulatory bodies soon, highlighting its strategic focus on diversifying into rare kidney diseases.Turning to industry trends, there is significant investment activity in antibody-drug conjugates (ADCs). French biotech company ADCytherix has raised $122 million to advance these targeted therapies into clinical trials. ADCs are gaining traction due to their precision in targeting cancer cells while minimizing damage to healthy tissues. Such advancements signal a potential shift in cancer treatment paradigms toward more targeted and less toxic therapies. Similarly, Tubulis raised an impressive Series C funding round to advance work on ADCs targeting ovarian and lung cancers, underscoring the growing interest in the potential of ADCs engineered to deliver cytotoxic drugs specifically to cancer cells.In another intriguing development, research has shown that a common diabetes drug can alleviate brain inflammation in female mice with multiple sclerosis. This finding exemplifies the growing interest in drug repurposSupport the show

In this bonus episode, we break down all the action from the Wuhan Open — where Iga Świątek delivered a dominant performance against Belinda Bencic to book her place in the quarter-finals against Jasmine Paolini. We analyze what's clicking for the World No. 1 on hard courts and how Paolini's fearless game could pose a challenge. Plus, a deep dive into the upcoming Aryna Sabalenka vs. Elena Rybakina showdown — a clash of power, precision, and rivalry that could define the road to the title in Wuhan. Tune in for tactical breakdowns, player insights, and predictions from the heart of the WTA tour.

Inflammation is the biological fire underlying most chronic disease. In this episode, Dr. Ritamarie Loscalzo returns with NEPT graduates Steph Jackson and Jennifer Whitmire to uncover how food fuels or fights inflammation.From autoimmune flares and brain fog to hidden cardiovascular risks, the trio explores how everyday foods, even so-called “healthy” ones, can lead to inflammation, and what to do about it. This episode will shift how you look at food, labs, and healing.What's Inside This Episode?How inflammation silently hides in autoimmune conditions, heart disease, and brain fogThe tests most practitioners miss when screening for inflammationWhy food “sensitivities” go far beyond IgA or IgG testingThe hidden downside of health foodsWhy ginger may be as powerful as turmeric and how both interact with the microbiomeHow oxytocin, hydration, and color diversity can be more anti-inflammatory than supplementsResources and Links:Download our FREE Functional Food GuideJoin the Next-Level Health Practitioner Facebook group here for free resources and community supportReserve your spot for ReInvent 2025 here for a deep dive into the impact of the microbiome on brain health including lab testing and geneticsVisit INEMethod.com for advanced health practitioner training and tools to elevate your clinical skills and grow your practice by getting life-changing resultsCheck out other podcast episodes hereGuest Resources and LinksSteph JacksonJoin the Friendly Flora Collective – Microbiome MembershipJennifer WhitmireJoin the Culinary Healing CircleGuest BioSteph JacksonIf you are ready to go deep with your digestive health and you need more than slippery elm, you will enjoy working with Nutritional Endocrinology coach, Steph Jackson. Steph loves customizing balancing programs for the micro biome, working with fermented foods, and looking at how the body systems work together. After finding and clearing the root cause of her severe physical pain and exhaustion, Steph has gone on to help others to do the same. She is also the proud founder of Crave Conscious, a non-dairy yogurt company based in Vancouver, British Columbia.Jennifer Whitmire On a mission to save body parts, Jennifer Whitmire is a culinary coach, health educator, and master herbalist specializing in autoimmune and thyroid health. Since 2017, she's taught women how to heal with food by restoring energy, balancing hormones, and repairing the gut through science-backed, whole food plant-based cooking and kitchen-based strategies.

Wojciech Fibak — przez lata dżentelmen polskiego sportu, symbol klasy, elegancji i sukcesu. Triumfator turniejów ATP, półfinalista Wimbledonu, reprezentant Polski w Pucharze Davisa. Kolekcjoner sztuki, biznesmen, człowiek salonów, który obracał się wśród elit — od Donalda Trumpa po czołowych artystów: De Niro, Hugh Grant, Mick Jagger. Ale za tą perfekcyjnie skrojoną fasadą kryje się historia, która podzieliła opinię publiczną. Głośny skandal opisany przez „Wprost”, zarzuty o międzynarodowe pośrednictwo w kontaktach z luksusowymi dziewczynami, to moralne dylematy, których echo słychać do dziś. Fibak, choć nigdy nie przyznał się do winy, do dziś mierzy się z cieniem tamtych publikacji. Jak sam dziś odnosi się do tych afer?  Co myśli o współczesnym świecie sportu i o tym, że Iga Świątek „nie daje się lubić”? Czy miliony, które stracił na produkcji „Psów” Pasikowskiego, były ceną za pasję, czy błędem człowieka, który zawsze grał va banque? Jakie były najdroższe obrazy, w które zainwestował? Dlaczego sprzedaje swój dom w Paryżu?  #płatnawspółpraca

Paul is joined by the first member of the Ball Boy Development Program, tennis fanatic and hair deity Benjamin Kersten, to talk the ins and outs of the Asian swing of the ATP and WTA tours.  We give some love to Iga and Coco for their recent form on and off the court, have some ideas for how to get butts in the seats at the China Open, and try to solve the mystery of Jannik Sinner's tummy.  And in Cross Court we have the case of Cup Sighs, to figure out how to make the schedule just a little bit less insane.  

In this episode, we explore the evolving role of surrogate endpoints in the management of IgA nephropathy (IgAN), with a particular focus on the significance of estimated glomerular filtration rate (eGFR). Of the completed Phase 3 trials in IgAN, one used time-weighted average eGFR, an area under the curve-based measure that reflects the average change in eGFR from baseline over a specified period, in this case, over the full 2-year study period. The other trial used total eGFR slope to describe the overall rate of change over 2 years. But what do these endpoints mean outside the setting of a clinical trial? Expert insights shed light on how proteinuria and eGFR trends can inform prognosis and guide treatment decisions in clinical practice over the long term. Listeners will gain a deeper understanding of how to interpret eGFR changes over time and apply this knowledge to optimize patient care. Designed for nephrology professionals, this episode offers practical, evidence-based perspectives on integrating these surrogate endpoints into the care of patients with IgAN. Supported by Calliditas Therapeutics Upon completion of the podcast, please take a moment to complete a brief survey: https://kidneyforms.tfaforms.net/4728109

We talk Carlos Alcaraz capturing the Tokyo title (while his biggest rival triumphed in Beijing) and Iga Świątek producing 70 unforced errors in a loss to Emma Navarro at the China Open.Follow us on YouTube or Apple Podcasts as well. Download the TennisONE APP for scores, stats, news, videos, player content, fan contests, and more (https://t1.app.link/Vansh)

The Asian swing is in full flight, and Tennis Weekly has all the latest headlines, results, and talking points from Tokyo, Beijing, and Shanghai. Carlos Alcaraz struck back with swift Laver Cup revenge over Taylor Fritz to capture his eighth title of the season in Tokyo, while Jannik Sinner bounced back in style to secure a second crown in Beijing. We also reflect on Gael Monfils' emotional announcement that he will retire at the end of 2026, celebrating the career of one of the sport's most electrifying entertainers.On the WTA side, the China Open is serving up shocks: Emma Navarro stunned world No. 1 Iga Świątek—dishing out a bagel along the way—while fellow Americans Jessica Pegula, Coco Gauff, and Amanda Anisimova also powered into the quarterfinals. Britain's Sonay Kartal has mounted a surprise run, but there was heartbreak for Emma Raducanu, who bowed out after another dramatic match filled with missed chances. Plus, Roger Federer has sparked debate with his comments on court speeds—are tournaments really slowing surfaces to favor Alcaraz and Sinner? And finally, we look ahead to Shanghai, where Sinner defends his title and Novak Djokovic makes his long-awaited return.BABOLAT Pure Strike OfferGo to babolat.com and use code: TENNISWEEKLY15 for an EXCLUSIVE 15% off their new Pure Strike Range(Offer valid until 7th October)SOCIALSFollow us on Twitter, Instagram, TikTok and YouTube, plus email the show tennisweeklypod@gmail.com.MERCHPurchase Tennis Weekly Merch through our Etsy store including limited edition designs by Krippa Design where all proceeds go towards the podcast so we can keep doing what we do!REVIEWS***Please take a moment to rate and review the show on Apple Podcasts, Spotify or wherever you get your pods. It really means a lot to us at HQ and helps make it easier for new listeners to discover us. Thanks!*** Hosted on Acast. See acast.com/privacy for more information.

Immune discusses the potential future of delivering vaccines by flossing your teeth and how antibodies in human milk shape the normal immune responses in newborns.  Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Floss-based vaccination (Nat Biomed Engineering 2025) Press article on Floss-based vaccine paper (Sci News) Human milk IgA promotes immune development (PNAS 2025) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Na dzień przed meczem Igi Świątek z Kamilą Osario w Pekinie ukazał się na jednym z portali taki tytuł, cytuję: Iga Światek – Camila Osorio. Wynik meczu, Kto wygrał w Pekinie? Co za szyba prędkość w informowaniu. Nie wiadomo, zapytali wróżki zębuszki, może raczej wróżki tenisówki. Jasnowidzenie podczas łikendowej imprezy mieli, doznali jednocześnie premonicji z antycypacją? Bo przecież nikt by aż takiego klikbajtka w normalnych warunkach nie wyprodukował. Jak mówię: w łikend musiało być twardo i biało. Ale dobra, zajrzałem, się dowiem, to u buka obstawię wynik. Na początek artykułu wstrząsająca informacja: Iga Świątek po wygraniu w Seulu przeniosła się do Pekinu. Czad. Krótka historia tenisa, z kim do tej pory wygrała Kolumbijka Osario i mamy wyjaśnienie, znów cytuję: Wynik meczu Światek Osorio poznamy po zakończeniu spotkania. O tym, kto wygrał mecz Światek Osorio w Pekinie, poinformujemy tuż po ostatniej akcji tego starcia. Koniec cytatu.

Vidcast:  https://www.instagram.com/p/DO6fzl7DKF3/The allergens include almonds, sesame, and certain food dyes. The affected cookies include Italian Mixed Vanilla Cookies, Italian Sesame Cookies, Vanilla Chocolate Dipped Cookies, Vanilla with Apricot Jam Cookies, Toasted Almond & Cherry Biscotti, and Vanilla Cookies with Raspberry Peach Jam.These recalled cookies were sold at Big Y stores in Connecticut and Springfield, Massachusetts; Stop and Shop stores in Connecticut; and all Nardelli's Connecticut stores with a Nardelli's label.  The other Connecticut stores include: Labonne's Supermarkets in Watertown and Prospect; Adam's Markets in Milford and Watertown; Highland Park Markets in Glastonbury, Manchester, and Farmington; Price Chopper in Newington, Bristol, and Middletown; T+K Supermarket in East Haven; Kensington Market in Kensington; Public Market of Newington; Raggozzino's in Plantsville; Lewis Farms in Southington; Durham Market in Durham; Liuzzi Gourmet Food Market in North Haven; Cappetta in West Haven; Roma Importing Market in Shelton; Walsh Market in Wolcott; Tops Market in Plantsville; The Local Gourmet in Southbury; CT Fresh Fruit and Produce in Wallingford; Wayside Market in Waterbury; Jimmy's Store in Torrington; La Molisana Sausage in Waterbury; New Fairfield Food Center Market in New Fairfield; Pat's IGA in Wolcott; Watertown Meat Center in Watertown; Tommy's Place and Market in Bristol; Cavallo's Deli and Imported Italian Food in Waterbury; and La Strega Italian Deli in Middlebury.Return these cookies to the place of purchase for a full refund. For more information, contact Gina Marie Bakery at 1-203-596-8007.https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/gina-marie-bakery-waterbury-issues-recall-cookies-due-undeclared-almonds-sesame-and-food-dyes#ginamarie #cookies #allergens #almonds #sesame #foodcoloring #recall

W dzisiejszym magazynie sportowym: sukces polskich siatkarzy, zakończenie Mistrzostw Świata w Lekkoatletyce i Iga Świątek ponownie zrobiła niespodziankę swoim fanom...

Have you ever felt like your body's playing tricks on you with endless fatigue, bloating, or hormone chaos? Candida overgrowth may be the sneaky culprit behind it all. Today's expert is here to fill you in on how candida links your gut health, thyroid function, and even hormones like estrogens and cortisol and his four-phase Candida protocol. In this episode of Salad with a Side of Fries, Jenn Trepeck is joined by Dr. Michael Biamonte to discuss his naturopathic journey and the development of BioCybernetics for diagnosing imbalances. They debunk myths about candida overgrowth being protective, discuss symptoms such as cognitive issues and chemical sensitivity, and detail his four-phase Candida protocol. Additionally, discover the benefits of organic acid tests, stool tests, and calprotectin for accurate diagnosis and treatment. Don't miss this eye-opening chat.The Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight loss, debunking myths, misinformation, and flawed science surrounding our understanding of nutrition and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.IN THIS EPISODE: (00:00) Dr. Biamonte explains how candida overgrowth feeds on B complex vitamins, converting carbohydrates into sugars(04:57) Dr. Biamonte's journey into naturopathy, driven by curiosity about nutrition when his father was ill(07:23) Dr. Biamonte develops a computer program called BioCybernetics(11:31) Candida is a cause of unusual reactions to vitamins linked to gut health imbalance(13:06) Reverse-engineering Candida treatment and the importance of rotating antifungals(17:29) Dr. Biamonte debunks the myth that Candida is protective, explaining that it suppresses immune system function(19:09) Symptoms of candida overgrowth, including fatigue, cognitive issues, gastrointestinal discomfort, eczema, and chemical sensitivity(25:43) Dr. Biamonte connects Candida to hormones, impacting thyroid function and Hashimoto's(28:03) Dr. Biamonte recommends organic acid tests and specific stool tests over blood tests to diagnose candida overgrowth accurately(31:52) Dr. Biamonte outlines the protocol to remove Candida(36:00) Dr. Biamonte explains that resolving candida overgrowth and leaky gut facilitates thyroid and adrenal recovery, but toxic metals must be addressed first(39:40) Why is there resistance to the protocolKEY TAKEAWAYS:Candida overgrowth significantly impacts gut health and hormones, particularly estrogens and cortisol, which can exacerbate conditions like Hashimoto's and thyroid function imbalances, requiring a targeted approach to address underlying dysbiosis. Dr. Michael Biamonte's four-phase Candida protocol involves a bowel cleanse, rotating antifungals, biofilm busters, and probiotics to restore gut flora, emphasizing the need to address leaky gut for effective treatment.Accurate testing, such as organic acid tests and stool tests (as opposed to unreliable blood tests), is crucial for identifying Candida overgrowth. Markers like stool pH, fecal IgA, and calprotectin indicate its presence.QUOTES: (15:48) "You were so ahead of your time in creating a program that is now essentially what people hope AI will do in medicine." Jenn Trepeck(20:00) “Candida, just like many other things of this nature, stresses out whatever your genetic weaknesses are to the point where that's how the symptoms manifest.” Dr. Michael Biamonte(22:07) “A lot of those things we associate with the B vitamin deficiency. So, the irony is that a B complex would also create a reaction in these same

We talk about Carlos Alcaraz defeating Jannik Sinner in the US Open final and how he improved to produce such a controlled and consistent display over the entire fortnight. Iga Świątek lost to Amanda Anisimova in US Open QF. How did the American avenge her Wimbledon loss?Follow us on Spotify or Apple Podcasts as well. Download the TennisONE APP for scores, stats, news, videos, player content, fan contests, and more (https://t1.app.link/Vansh)

The pod hits triple digits, and Sam immediately blows the budget - dropping $663 on hotel laundry in New York. That fiasco sets the tone for an episode packed with shaky quarterfinal predictions, a surprisingly deep dive into life choices, and a full Round 4 recap. From Anna Wintour lurking courtside to Jason Biggs randomly popping up, the celebrity sightings nearly stole the show… nearly. The guys break down Felix's revival, Alcaraz's shot-of-the-year candidate, Novak's effortless cruise, and Fritz's eternal struggle against him. On the women's side, Iga keeps steamrolling, Osaka looks dangerous again after taking out Coco, Pegula is gliding quietly under the radar, and Krejcikova delivered what might be the match of the tournament. Things wrap up with one of the wildest Life Advice questions yet. The guys dish out surprisingly heartfelt guidance—sandwiched between trash talk about their bracket challenge and scheming over who's doomed to write and sing a jingle. Chaotic, sharp, and accidentally sincere… basically the perfect 100th episode. 00:00 Intro to Our 100th Show! 00:37 Dry Cleaning in New York 02:22 Celebrity Sightings 03:27 Recap of Round of 16 Matches 05:27 Felix / Musetti Surprising Performances 09:57 Novak's Dominant Form 11:52 Alcaraz's Shot of the Year 12:54 Quarterfinals Preview / Predictions 15:17 Women's Quarterfinal Highlights 17:35 Match of the Tournament: Krejcikova vs. Townsend 19:21 Osaka vs. Coco Gauff Analysis 23:27 Life Advice Segment 25:56 Bracket Challenge Update and Goodbye!

We're kind of winging it for this US Open preview. It's a bit too late for a Cincy recap, so we're talking about major themes -- like Coco's coaching overhaul, Iga's mid-season surge, the guys not named Carlos or Jannik -- and sprinkling in some results. We talk about what worked and what didn't in the mixed doubles exhib-- I mean the prestigious and successful mixed doubles tournament featuring the world's best players. Plus we settle some scores and probably create a few new beefs, but what the hell, this is the last major of 2025 and literally our 43rd Slam preview. 1:00 The major storylines in the women's draw: I warned you Iga was coming! + Coco drops the GripMD 15:00 Men's storylines: Djokovic LoseWatch, the also-rans  21:05 The mixed doubles experiment 31:30 Mardy Fish comes for Rajeev Ram out of nowhere 35:50 Not Parks and Vavassori liking fake news homophobic posts on IG 38:45 Women's draw preview 51:25 Men's draw preview  67:10 US Open artwork: Honoring Althea Gibson in death but not in life

Ep.143 Have you ever wondered if it's possible to improve your dog or cat's longevity? If your dog is dealing with allergies, hot spots, gut issues, or mysterious behaviors, Rita is truly a wealth of knowledge on pet care that doesn't come around often. Rita Hogan, a holistic canine herbalist and author of “The Herbal Dog”,  breaks down everything you need to know about healing your dog with herbs, diet, and even your emotional regulation. Rita walks us through the top 5 herbs for dogs, why our animals are a reflection of our own nervous system dysregulation, how to heal our dogs' allergies, food intolerances, and aid antibiotic recovery with simple herbal remedies that can be easily made at home. She is truly the missing piece of the puzzle in our Western pet care system and generously shares her experience on improving your dog's day-to-day health and capacity for longevity.     HERE'S THE JUICE Breaking down Rita's go-to post- antibiotic recovery protocol and the herbal alternatives that can  protect your pet. The top 5 herbs every dog should be taking to support longevity. What your vet won't tell you about flea and tick medicine and what to look out for The importance of organ health The key  to decoding your pet's behavior is to spot underlying health issues before they escalate Why fixing your dog's microbiome could be the key to longevity and the three simple steps you can take to start supporting their gut health Why your dog could mirror your stress, and the calming ritual that works for you both to support a healthy relationship     TimeCodes: 2:54– talking about Metronidazole 3:15— Blackberry leaf as a solution to diarrhea  5:43— Antibiotic recovery protocol from Rita's book to fix microbiome 6:15— Lily chen tip to restore dog microbiome 9:15—Rita explains the importance of the gut being “prepared” so probiotics work 11:11— How to prepare the gut and make sure probiotics work: Three things (collustrum, plantains, yeast) that increase will boost the secretions of IGA 12:50— How did Rita become a canine herbalist 17:20— Issues with Feel and tick meds and hear worm meds 19:52— Knowing based behavioral cues of a dog what organ issues are 27:00— herbs to use for lymphomas 32:00— importance of balancing both you and your dog's nervous system 37;27— what is the limbic system and how is that involved in the immune system 43:00—talking about how bad phones, wifi, and smart homes are for us and for our dogs 49;45—importance of going back to the basics 51;47— top herbs for dogs 1:01:00- creating a healing protocol and digestive enzymes 1:14:00 - Proteins to feed dogs based on hot or cold energy 1:20:00- oral health links to kidneys 1:30:00- how to stabilize the nervous system for dogs 1:34:00- Using german chamomile to calm nervous system 1;40:00- flea and tick medicine     MY FIRST SONG, “ANOTHER LOVER” IS OUT NOW ⭐️❤️