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Nathan Jones, founder and CEO of Xlear, Inc., reveals xylitol's role in supporting oral and nasal “gateway” microbiomes by selectively starving acid-producing Strep mutans rather than indiscriminately killing bacteria, and warns that harsh mouthwashes can disrupt beneficial oral bacteria linked to nitric oxide production and possibly blood pressure. Jones outlines Spry and Xlear products (gum, mints, toothpaste, mouthwash, dry-mouth “Rain,” and upcoming gummy candies, a new dental probiotic with added nutrients, and a direct-to-consumer oral bacteria test kit with pre/post tracking). He discusses diet, emphasizing sugar as a key driver of cavities and criticizing limited focus on sugar in a Surgeon General oral health report. In part two, Jones describes ongoing and planned legal actions against the FTC over shifting evidentiary standards and reputational damage, then reviews Xlear's allergy and respiratory approach via nasal hygiene, product tiers (regular, Max with quercetin, Rescue botanicals, and a decongestant), and a forthcoming ectoine-based spray to support mucus barrier integrity.
Recorded live at EIC 2026 in Berlin, Jeff and Jim sit down with Martin Sandren, IAM Product Lead at IKEA, for a wide-ranging conversation covering nearly every corner of modern identity security. Martin shares what has changed since his first IDAC appearance on episode 293, including the rise of AI, growing interest in digital sovereignty, and the maturing shared signals framework. The conversation moves through risk-based defense in depth, tiered MFA rollout strategies, session management, and the real challenge of trusting AI to make security decisions. Martin introduces identity dark matter and explains how IVIP can surface the 95-plus percent of applications that never reach an IGA system. The episode also covers shadow AI, MCP server risks, the SaaSpocalypse debate, and the EU AI Act. It closes on a grounded note: solar panels.Connect with Martin: https://www.linkedin.com/in/martinsandren/Connect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at http://idacpodcast.comTIMESTAMPS00:00 Welcome and EIC 2026 intro01:47 What has changed in two years: AI, sovereignty, shared signals03:06 Martin's EIC presentations: AI for IAM and IAM for AI04:46 Can you prioritize one direction over the other?07:13 What would it take to trust AI making identity decisions?09:32 AI-enhanced detection and risk-based session management13:07 Session invalidation and the shared signals framework14:11 Defense in depth and right-sizing privileges18:25 MFA today: any MFA versus phish-resistant MFA19:17 AI chatbots, enterprise LLMs, and shadow AI23:11 MCP servers, NHI risk, and return on risk thinking27:00 AI configuring IAM systems: how close are we?31:30 LLM costs, the SaaSpocalypse, and enterprise AI futures40:10 Identity dark matter and the IVIP concept44:16 CMDB versus IVIP: do you need both?46:18 The EU AI Act and building an AI governance registry49:18 Where to start: get your AI inventory in place first50:00 Closing thoughts and the solar panel tangentKEYWORDSAI for IAM, IAM for AI, identity dark matter, IVIP, IGA, shared signals framework, phish-resistant MFA, defense in depth, session management, MCP servers, NHI, shadow AI, SaaSpocalypse, EU AI Act, AI governance, zero standing privilege, EIC 2026, IKEA, IDAC, Identity at the Center, Jeff Steadman, Jim McDonald, Martin Sandren
Check out the video version of this episode on HCPLive!Finerenone's expansion into non-diabetic kidney disease is prompting a broader rethink of how chronic kidney disease is measured, mechanistically understood, and treated across its many causes.On an episode of Don't Miss a Beat recorded at the 10th Annual Heart in Diabetes Meeting, hosts Stephen Greene, MD, meeting co-chair and heart failure specialist at Duke University School of Medicine, and Muthiah Vaduganathan, MD, MPH, codirector of the Center for Cardiometabolic Implementation and cardiologist at Brigham and Women's Hospital, spoke with Katherine Tuttle, MD, professor of medicine at the University of Washington, about the phase 3 FIND-CKD trial and how it informs on the overall role of finerenone (Kerendia) in management of cardiovascular-kidney-metabolic syndrome.FIND-CKD showed finerenone slowed total estimated glomerular filtration rate (eGFR) slope by 0.7 mL/min/1.73 m² per year versus placebo, irrespective of diagnosis. Much of the discussion focused less on the number and more on why it counts as clinically meaningful.Drawing on CKD Prognosis Consortium data from hundreds of thousands of patients, Tuttle explained why eGFR slope reliably predicts kidney failure when a trial runs at least 2 years. CKD progresses rather than striking as a discrete event, so the field has moved toward endpoints measurable without waiting for organ failure or death.On safety, hyperkalemia occurred more often with finerenone than placebo, about 12% versus 3%, though fewer than 1% of patients discontinued. The framing was practical, with background SGLT2 inhibition expected to lower the risk.Mechanism anchors much of the conversation between Tuttle, Greene, and Vaduganathan.Tuttle highlighted how glomerular diseases, like IgA nephropathy, are immunologic disorders needing disease-specific therapy, yet all CKD converges on shared final common pathways of inflammation and fibrosis. Broad agents like finerenone target those pathways, making combination therapy the emerging model, pairing treatment of the inciting disease with control of progression.The group also discussed the field's trend toward precision nephrology. Protocol biopsies from the Kidney Precision Medicine Project showed only about half of patients labeled as diabetic CKD had classic diabetic nephropathy. A parallel to oncology followed, where deep phenotyping replaced uniform regimens, suggesting not every patient will need every drug.Tuttle positioned finerenone alongside renin-angiotensin system inhibitors and SGLT2 inhibitors as an emerging pillar for non-diabetic CKD, with GLP-1 receptor agonists and endothelin antagonists possibly to come. A pooled analysis of FIDELIO-DKD, FIGARO-DKD, and FIND-CKD showed roughly 30% reductions in kidney and cardiovascular outcomes and an 11% drop in all-cause mortality. The closing point held the cardiorenal patient often arrives through either specialty's door, making preservation of organ function and quality of life the shared aim.Relevant disclosures for Tuttle include Alnylam, AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly, GSK, Novo Nordisk, Roche, and Travere Therapeutics. Relevant disclosures for Vaduganathan include Amgen, AstraZeneca, Bayer AG, Boehringer Ingelheim Pharmaceuticals, Cytokinetics, Lexicon, and others. Relevant disclosures for Greene include Amgen, AstraZeneca, Bayer Healthcare Pharmaceuticals, Boehringer Ingelheim Pharmaceuticals, Cytokinetics, and others.References: Heerspink HJL, Neuen BL, Agarwal R, et al. Finerenone in Persons with Chronic Kidney Disease without Diabetes. N Engl J Med. Published online June 4, 2026. doi:10.1056/NEJMoa2604625 Bayer. Bayer to Present First Full FIND-CKD Results Investigating KERENDIA® (finerenone) in Non-Diabetic Chronic Kidney Disease at ERA 2026. Bayer.com. Published June 2, 2026. Accessed June 21, 2026. https://www.bayer.com/en/us/news-stories/kerendia-in-non-diabetic-chronic-kidney-disease
We've got another segment from our friends at Boulder Valley Frequency today featuring prolific music journalist, outdoorsmen and Ward-adjacent resident Grayson Haver Currin. Grayson has profiled Willie Nelson, Peter Frampton, Tame Impala and of course, Paul McCartney. Today, he explains how he found his way to music journalism while telling some pretty cool stories along the way.AlsoBlack Hawk water issue gets multimillion dollar fixNederland explores IGA for fire mitigationCentral City talks affordable housingFormer Gilpin resident wins a PeabodyYou can watch the Peabody award-winning KMBC-TV documentary Restrained here: kmbc.com/article/chronicle-restrained-law-enforcement-restraint-documentary-investigation/64592751Our theme song is courtesy of singer-songwriter Brittney Wagner. Stream her record Better off Dead here. Support the showThank you for listening to The Mountain-Ear Podcast, featuring news and culture from peak to peak! Additional pages are linked below.If you want to be involved in the podcast or paper, contact:Barbara Hardt, our editor-in-chief, at info@themountainear.comTyler Hickman, multimedia producer, at tyler@themountainear.comJamie Lammers, podcast host, at media@themountainear.comGeneral inquiries: frontdesk@themountainear.comHead to our website for all of the latest news. Subscribe to The Mountain-Ear in print and online.Submit local events to promote them in the paper and on our website.Find us on Facebook @mtnear and Instagram @mtn.earListen and watch on YouTube today.Share this podcast by scrolling to the bottom of our website home page or by heading to our main hub on Buzzsprout.Thank you for listening!
Hitzewarnung bei uns, Rohrbruch an Gladbecker Kreuzung, IGA 2027 plant Weltrekordversuch, Befragung zum Mobilitätsverhalten in Gelsenkirchen
This episode is presented courtesy of SailPoint. Rob Sebaugh, Senior Identity Strategist at SailPoint, joins Jeff and Jim for a wide-ranging conversation on the past, present, and future of identity governance. Rob brings more than two decades of practitioner experience to the table, including 16 years running large-scale identity programs before making the move to the vendor side. The conversation covers what identity governance means today, why it must move to the forefront rather than be treated as an afterthought in an agentic world, and how organizations need to think fundamentally differently about non-human identities. Jeff and Jim explore the concept of treating AI as a first-class identity, how AI is beginning to replace rubber-stamp access certifications, the shift toward policy-based access control, and the practical path toward zero standing privilege. The episode wraps with a lighter conversation about Rob's 3D printing hobby.About SailPoint:SailPoint (Nasdaq: SAIL) is defining the new era of adaptive identity security. In a world where non-human identities now significantly outnumber humans, our AI-powered platform unifies identity, security, and data intelligence to protect today's enterprise from advanced identity-based threats. We deliver the identity solution that spans both the breadth of identities and the depth of context needed to drive real-time access with confidence. Built on principles like zero-standing privilege and contextualized risk, our SailPoint platform transforms identity from a point of vulnerability into a powerful security advantage. Trusted by many of the world's leading organizations, SailPoint secures the enterprise with intelligent, autonomous identity security.Learn more about SailPoint: https://www.sailpoint.com/Connect with Rob: https://www.linkedin.com/in/rob-sebaugh-1ba9013/Connect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at http://idacpodcast.comTimestamps:00:00 Introduction00:48 Rob Sebaugh and the identity strategist role at SailPoint04:38 Practitioner advice from the field07:49 What SailPoint does: the hotel key analogy11:04 Buying identity technology means buying a business process13:30 What identity governance is and why it still matters16:47 Risk-appropriate governance and privileged access19:39 Non-human identities and the scale of the agentic challenge22:57 Treating AI as a first-class identity24:28 When AI makes governance decisions: beyond rubber stamping28:04 Is identity governance a binary decision?29:58 Securing data inside AI and large language models34:09 Identity: the field that reinvents itself35:01 Identity as the new control plane37:21 Is all access privileged access?40:25 Zero standing privilege in practice44:22 Innovation, continuous identity, and what SailPoint is building46:28 Identity posture management50:13 Practitioner advice for the next three to five years53:00 The future of IGA in ten years57:44 Lighter note: 3D printing with Rob Sebaugh1:05:35 Final thoughts on SailPointKeywords: Rob Sebaugh, SailPoint, identity governance, identity security, IGA, non-human identities, agentic AI, zero standing privilege, just-in-time access, identity posture management, control plane, zero trust, policy-based access control, AI certification, rubber stamping, sponsor spotlight, IDAC, Identity at the Center, Jeff Steadman, Jim McDonald
My new favorite criminal and should you divorce someone for ruining your concert? Send us a voice message https://www.speakpipe.com/ChunkMcBeefChest Linktree https://linktr.ee/chunkmcbeefchest
Recorded live at EIC 2026 in Berlin, Jeff and Jim sit down with Thomas Zarnhofer, IAM Architect at SPAR-ICS, the IT unit of the SPAR Austria Group, which operates roughly 3,000 retail stores and 32 shopping centers across Central Europe. Thomas shares his experience leading a full IGA transformation from a decade-old on-premise system to a modern cloud-based platform. The conversation covers the shift from a contract-based to a person-based identity model, the importance of cleaning data before migration begins, a three-phase framework of Foundation, Migration, and Adoption, lessons learned from running two systems in parallel, and a look at how AI could make IGA predictive. The episode ends with Thomas's tips for visiting Austria.Connect with Thomas: https://www.linkedin.com/in/tzarnhofer/Connect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at http://idacpodcast.comTimestamps00:00 Introduction and EIC 2026 Setting02:00 Thomas's Identity Origin Story03:38 What Is SPAR-ICS?04:21 The Catalyst for IGA Modernization07:43 Contract-Based vs Person-Based Identity Models09:22 Consolidating Master Data Sources11:39 Data Quality and Attribute Ownership13:34 Partnering with HR for Clean Data16:43 Data Analysis: Why They Chose Excel Over AI17:53 Clean Your Data Before You Migrate18:23 The Three Phases: Foundation, Migration, Adoption20:12 Driving Adoption Across the Organization21:10 Running Two Systems in Parallel22:47 Challenge Everything vs Lift and Shift27:23 Surprises in the Cloud IGA Journey29:02 Testing Requirements in the Cloud29:51 AI and the Future of IGA32:25 AI Chatbots and Role Discovery35:30 Scoping Business Role Visibility36:06 Life Outside IAM: Travel and Austria TipsIAM, IGA, Identity Governance, IGA Migration, On-Premises to Cloud, Identity Model, Contract-Based Identity, Person-Based Identity, Master Data, Data Quality, HR Integration, Joiner Mover Leaver, Cloud IGA, SPAR-ICS, Retail IAM, EIC 2026, AI in IGA, Predictive IGA, Role Management, Access Governance, IDAC, Identity at the Center, Jeff Steadman, Jim McDonald, Thomas Zarnhofer
Roland Garros 2026 is officially in the books — and it delivered one of the most dramatic fortnights in recent memory. Faizan sits down with legendary tennis journalist Steve Flink to break down EVERYTHING: Alexander Zverev's emotional Grand Slam breakthrough, Jannik Sinner's almost unexplainable collapse against Francisco Cerundolo, Novak Djokovic's stylish exit to João Fonseca, and Mirra Andreeva becoming the tournament's youngest champion in years.We also dig into Aryna Sabalenka and Iga Świątek's rough fortnights, what's next for Coco Gauff, and why the next generation (Fonseca, Mensik, Fils) might finally be ready to take over. Plus: an early look ahead to Wimbledon.
Want to be featured on the next Q&Andy? Send us a video on our socials or email us at askandy@servedmediagroup.com Andy Roddick welcomes Rafael Nadal and documentary director Zach Heinzerling for a special edition of Q&Andy, diving deep into Nadal's new documentary series and the emotional final chapter of one of the greatest careers in tennis history. Rafa opens up about the difficult decision to allow cameras into his private world, the challenge of documenting injuries, family life, and retirement in real time, and why he ultimately trusted the filmmaking process. He also shares his perspective on watching Roland Garros from the outside, mentoring stars like Carlos Alcaraz and Iga Świątek, and what life looks like now beyond the tour.
Privileged Access Management has outgrown the vault. In this episode, Matthias sits down with lead analyst Alejandro Leal, author of KuppingerCole's newly released PAM Leadership Compass, to explore how the definition of privilege itself has changed, what NHIs and agentic AI mean for PAM, and why deployment sovereignty is now a boardroom conversation. Key Topics: ✅ How the definition of "privilege" has shifted from admin accounts to dynamic runtime identity capabilities✅ PAM convergence with IGA, CIEM, ITDR, SIEM, and SOAR — the end of the standalone PAM product✅ Non-Human Identities (NHIs) and agentic AI: the silent accumulation of machine privilege✅ Just-in-time access: the gap between concept and operational reality✅ Deployment sovereignty: who controls the keys to the kingdom — SaaS, on-prem, or hybrid?✅ AI and ML in PAM: separating genuine innovation from marketing inflation "Most enterprises can tell you the number of employees they have — very few can tell you the number of machine identities." If that sounds familiar, this episode is for you.
W najnowszym odcinku „Podkastu psychologicznego” Joanna Cieśla gości w studiu trenera mentalnego i mówcę motywacyjnego: Jakuba B. Bączka, który opowiada o tym, dlaczego ślepa motywacja bywa przereklamowana i jak mądrze redefiniować współczesne pojęcie sukcesu. Jak wygląda psychologia sportu na samym szczycie i dlaczego tradycyjna motywacja do działania często nie wystarcza, by utrzymać się w tym elitarnym jednym procencie. Rozmawiamy o kulisach pracy z największymi gwiazdami: Jakub B. Bączek dzieli się doświadczeniami ze współpracy z Robertem Lewandowskim i z kadrą narodową, z którą zdobył mistrzostwo świata siatkarzy w 2014 r. Na przykładach takich mistrzyń jak Naomi Osaka, Iga Świątek czy Justyna Kowalczyk analizujemy, jaką cenę płaci się za wielkie wygrane. W odcinku mówimy także o tym, czym są pracoholizm oraz lęk uogólniony, które nierzadko kryją się za fasadą spektakularnych osiągnięć. Rozmawiamy o presji, o tym, jak działa perfekcjonizm i jak sobie z nim radzić w codziennym życiu. Wspólnie zastanawiamy się, gdzie leżą pułapki bycia zbyt miłym, jak odnaleźć upragniony sens życia i spokój wewnętrzny bez konieczności ciągłego spalania się w pracy. Mówimy oczywiście również o relacjach i nowym podejściu do zarządzania. Jakub B. Bączek wyjaśnia, jak powinna wyglądać współczesna psychologia biznesu i jak prowadzić biznes z uważnością na drugiego człowieka. W czasach gdy model B2B (biznes do biznesu) ustępuje filozofii H2H (human to human), podpowiadamy, jak planować czas i jak zachowywać się w pracy, by stawiać zdrowe granice wzajemnego dostosowywania się. Ten odcinek jest dla wszystkich, którzy czują się zmęczeni ciągłym pędem za produktywnością i szukają inspiracji, jak połączyć ambicję z troską o własne zdrowie psychiczne. 3 rzeczy, których dowiesz się z odcinka: 1. Dlaczego ślepa motywacja jest przereklamowana, a poszukiwanie sensu buduje trwalsze efekty niż presja na sukces. 2. Jak wygląda psychologia sportu na samym szczycie na przykładzie Igi Świątek czy Roberta Lewandowskiego. 3. Czym różni się podejście B2B od H2H w nowoczesnej psychologii biznesu i jak budować relacje oparte na człowieczeństwie. Oś czasu: 00:00:00 - Najciekawsze fragmenty 00:01:46 - Motywacja i poszukiwanie sensu: co działa skuteczniej? 00:05:44 - Jak nie ulegać presji i zachować spokój wewnętrzny. 00:11:28 - Redefiniowanie sukcesu, czyli wygrana bez antydepresantów. 00:13:45 - Psychologia sportu i sekrety 1 proc. najlepszych na świecie. 00:21:10 - Polska specyfika sportów drużynowych. 00:27:10 - Jak sportowcy zmieniają świat? 00:35:27 - Pracoholizm i wypalenie zawodowe: jak skutecznie im przeciwdziałać? 00:46:00 - Uważność czy algorytmy? Nowe technologie w biznesie i filozofia H2H.
Privileged Access Management has outgrown the vault. In this episode, Matthias sits down with lead analyst Alejandro Leal, author of KuppingerCole's newly released PAM Leadership Compass, to explore how the definition of privilege itself has changed, what NHIs and agentic AI mean for PAM, and why deployment sovereignty is now a boardroom conversation. Key Topics: ✅ How the definition of "privilege" has shifted from admin accounts to dynamic runtime identity capabilities✅ PAM convergence with IGA, CIEM, ITDR, SIEM, and SOAR — the end of the standalone PAM product✅ Non-Human Identities (NHIs) and agentic AI: the silent accumulation of machine privilege✅ Just-in-time access: the gap between concept and operational reality✅ Deployment sovereignty: who controls the keys to the kingdom — SaaS, on-prem, or hybrid?✅ AI and ML in PAM: separating genuine innovation from marketing inflation "Most enterprises can tell you the number of employees they have — very few can tell you the number of machine identities." If that sounds familiar, this episode is for you.
"Iga raamat hakkab oma elu elama, igal raamatul on oma saatus," ütleb kirjanik, kirjastaja ja käsikirjade toimetaja Epp Petrone, kelle kirjastuse Minu-sari on jõudnud kahesajanda raamatuni.
Andy Roddick breaks down results from Day 12 of 2026 Roland Garros. Roddick talks through Maja Chwalińska's shocking run to the Roland Garros final — only the second women's qualifier in Open Era history to reach a Grand Slam final — breaking down her elite anticipation, subtle court positioning, and how she dismantled Diana Shnaider without overpowering her. Plus, why Mirra Andreeva has been the best player at the tournament from start to finish, how her serve and ability to play through wind gives her the edge in Saturday's final, and a preview of the men's semifinals. COMMENT BELOW: Who do you have winning the women's final? Sign up for the Newsletter & Live Chat w/ us during matches! https://servedmedia.substack.com/ Follow Served with Andy Roddick: Instagram: https://www.instagram.com/servedpodcast/ TikTok: https://www.tiktok.com/@served_podcast Learn more about ServiceNow here: https://www.servicenow.com/?campid=271869&cid=pc:brd:brnd:served:26q1:paitwfp_audioredirect_PAITW2_GAI_PAITWFP_HostRead_:none:br_ams:awa&utm_medium=podcasts&utm_source=served --- --- --- Served with Andy Roddick is your home for all the ATP and WTA Tours Tennis Breaking News, Draw Previews, Match Recaps, Player Interviews, Match Previews and more. We cover the largest tournaments throughout the season including the Australian Open, Roland Garros, Wimbledon, US Open, Shanghai and talk about the best players including Novak Djokovic, Carlos Alcaraz, Jannik Sinner, Rafael Nadal, Coco Gauff, Iga Świątek, Naomi Osaka, Aryna Sabalenka, Alexander Zverev, Daniil Medvedev, Emma Raducanu, Stefanos Tsitsipas, Roger Federer, Jack Draper. --- --- --- #RolandGarros #RolandGarros2026 #Chwalinska #Andreeva #FrenchOpen #FrenchOpen2026 #Tennis #GrandSlam #WTA #WTATennis #QuickServed Thank you to our sponsors: ServiceNow Learn more about your ad choices. Visit megaphone.fm/adchoices
Andy Roddick breaks down results from Day 13 of the 2026 Roland Garros. Roddick discusses Alexander Zverev's dominant semifinal win over Jakub Menšík, why Menšík's tactics never allowed him to settle into the match, and how Zverev has handled the pressure of becoming the clear tournament favorite. Plus, Roddick reacts to Matteo Arnaldi's heartbreaking withdrawal due to illness after one of the most physically demanding runs in Grand Slam history, what it means for the men's final for Flavio Cobolli, and a quick look ahead to Mirra Andreeva vs. Maja Chwalińska in the women's final match. COMMENT BELOW: Who do you have winning the men's final? Sign up for the Newsletter & Live Chat w/ us during matches! https://servedmedia.substack.com/ Follow Served with Andy Roddick: Instagram: https://www.instagram.com/servedpodcast/ TikTok: https://www.tiktok.com/@served_podcast Learn more about ServiceNow here: https://www.servicenow.com/?campid=271869&cid=pc:brd:brnd:served:26q1:paitwfp_audioredirect_PAITW2_GAI_PAITWFP_HostRead_:none:br_ams:awa&utm_medium=podcasts&utm_source=served --- --- --- Served with Andy Roddick is your home for all the ATP and WTA Tours Tennis Breaking News, Draw Previews, Match Recaps, Player Interviews, Match Previews and more. We cover the largest tournaments throughout the season including the Australian Open, Roland Garros, Wimbledon, US Open, Shanghai and talk about the best players including Novak Djokovic, Carlos Alcaraz, Jannik Sinner, Rafael Nadal, Coco Gauff, Iga Świątek, Naomi Osaka, Aryna Sabalenka, Alexander Zverev, Daniil Medvedev, Emma Raducanu, Stefanos Tsitsipas, Roger Federer, Jack Draper. --- --- --- #RolandGarros #RolandGarros2026 #Arnaldi #Zverev #Mensik #Cobolli #FrenchOpen #FrenchOpen2026 #Tennis #GrandSlam #ATP #WTATennis #QuickServed Thank you to our sponsors: ServiceNow Learn more about your ad choices. Visit megaphone.fm/adchoices
Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we're diving into some of the most significant advancements in scientific research, clinical trials, and regulatory landscapes within the industry. These developments are shaping the future of patient care and drug development significantly. Starting with Legend Biotech's LB2501, which achieved an impressive 100% response rate in a Phase 1 study for non-Hodgkin lymphoma using in vivo CAR T-cell therapy. This breakthrough highlights the transformative potential of CAR T-cell therapies in oncology, especially for B-cell lymphomas. Such success opens the door for accelerated regulatory pathways, offering hope to patients with limited treatment options. In another key development, JJP Biologics shared positive interim data from its Phase 1b trial of nebaprubart targeting CD89 in linear IgA disease. This monoclonal antibody is promising in treating autoimmune conditions by targeting specific disease mechanisms. Meanwhile, GSK's Velzatinib (IDRX-42) achieved a 61% response rate in Phase 1/1b trials for gastrointestinal stromal tumors, showing efficacy against cases resistant to treatments like imatinib. Johnson & Johnson's Nipocalimab met its primary endpoint in a Phase 2 study for systemic lupus erythematosus, underscoring the potential of FcRn blockade in managing autoimmune diseases. Zenas Biopharma's Phase 3 data for Obexelimab targeting CD19/FcγRIIB in IgG4-related disease further emphasizes the role of targeted therapies in managing complex autoimmune disorders. On the regulatory front, Foundation Medicine's FoundationOne Blood Test received FDA approval as a companion diagnostic for Pfizer's Talzenna (talazoparib) to treat prostate cancer with homologous recombination repair gene mutations. This approval underscores the growing importance of precision medicine and companion diagnostics in tailoring cancer treatments based on genetic profiles. Additionally, Lupin and Natco Pharma secured FDA approval for their generic version of Eribulin Mesylate Injection, essential for reducing healthcare costs and improving patient access to vital therapies. Eli Lilly's collaboration with Ascidian Therapeutics focuses on RNA exon editing for kidney diseases, potentially revolutionizing treatment approaches by correcting genetic errors at the RNA level. This partnership reflects a burgeoning interest in RNA-based therapies and their capacity to address unmet medical needs. Regeneron expanded its pact with CytomX Therapeutics to develop conditionally active bispecific antibodies, emphasizing innovation in oncology drug discovery. Such collaborations combine expertise across companies to expedite cutting-edge therapies' development. In terms of funding, NewLimit's successful $435 million Series C round aims to advance epigenetic reprogramming medicine towards human trials. This initiative highlights the burgeoning field of aging biology and its implications for extending healthy human lifespan through innovative therapeutic approaches. Similarly, Immu Biosciences raised $53 million to enhance its immunology platform using AI/ML technologies, underscoring AI and machine learning's critical role in accelerating drug development processes. Turning our gaze towards China's expanding influence on the global biotech stage, Akeso's presentation at ASCO 2026 marked a significant milestone as it became the first-ever Chinese dataset featured in a plenary session. This achievement underscores China's growing prominence in biotechnology and highlights its commitment to advancing innovative medical solutions globally. Simultaneously, Gilead's strategic partnership with Cencora aims to enhance access to CAR-T therapies like Yescarta and Tecartus by expanding their network of treatment centers. CAR-T therapies represent a paradigm shift in cancer treatment by offering personalized options for certain types of cancer. Despite challenges such as Roche's setbacks with its oral SERD drug giredestrant in breast cancer trials, innovation continues unabated. Zevra Therapeutics' launch of Miplyffa for Niemann-Pick disease type C exemplifies efforts to transform rare disease markets by improving patient outcomes through increased access and tailored treatment strategies. Finally, Eli Lilly's acquisition spree reflects broader trends where pharmaceutical companies increasingly integrate Chinese innovations into their development pipelines. This period marks a transformative phase characterized by collaboration between global pharma giants and Chinese biotechs, signaling an era where innovation is globalized and aimed at addressing critical healthcare challenges worldwide. These advancements reflect a dynamic period of innovation within the pharmaceutical and biotech industries. The focus on personalized medicine, targeted therapies, and groundbreaking technologies like RNA editing indicates a shift towards more precise treatment modalities. As these discoveries transition from research phases to clinical applications, they hold the potential to transform patient care significantly. Strategic partnerships and substantial funding initiatives illustrate a robust ecosystem supporting these innovations' rapid advancement. As regulatory bodies continue approving novel therapeutics and diagnostics, the emphasis on personalized healthcare will likely drive future developments, ultimately leading to improved patient outcomes worldwide. As we continue navigating these developments, it's clear that the pharmaceutical and biotech sectors are on the cusp of transformative breakthroughs that promise to redefine healthcare delivery across multiple domains. Thank you for tuning into Pharma Daily; stay informed and stay ahead.Support the show
This episode and the Identity at the Center podcast is supported by CrowdStrike. Learn more at crowdstrike.com.Jeff Steadman and Jim McDonald sit down with Scott Kriz, GM of Continuous Identity at CrowdStrike, for a deep dive into continuous identity, zero standing access, and the convergence of identity and security. Scott traces his path from co-founding Bitium, to selling it to Google Cloud, to building SGNL and ultimately joining CrowdStrike. The conversation covers how continuous identity works in practice, why traditional PAM and IGA fall short in a real-time world, and what the rise of agentic AI means for identity governance at scale. Connect with Scott: https://www.linkedin.com/in/scottkriz/Learn more about Crowdstrike: https://www.crowdstrike.com/en-us/platform/next-gen-identity-security/caep/?idacConnect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at http://idacpodcast.com00:00:00 Introduction and welcome00:01:21 How Scott got into identity and co-founded Bitium00:03:55 Selling to Google Cloud and the inspiration for SGNL00:05:02 Continuous identity and zero standing access explained00:09:13 Defining continuous identity at CrowdStrike00:10:20 How continuous identity differs from PAM and IGA00:15:06 Data as the foundation for continuous identity00:19:29 Open ecosystems, Shared Signals Framework, and CAEP00:25:26 Agents, identity chaining, SPIFFE, SPIRE, and MCP gateways00:33:02 Identity inside CrowdStrike's broader security strategy00:37:27 Identity security budgets and ROI-driven purchasing00:40:04 Agentic scale and the need for automated identity controls00:43:39 The SGNL acquisition: what it means for both companies00:50:25 Zero trust as a real architectural framework00:54:00 Helicopter skiing, avalanches, and staying presentKeywords: IDAC, Identity at the Center, Jeff Steadman, Jim McDonald, Scott Kriz, CrowdStrike, SGNL, continuous identity, zero standing access, PAM, IGA, zero trust, agentic AI, non-human identity, NHI, SPIFFE, SPIRE, MCP, identity security, real-time authorization, cybersecurity
Guest: Dr. Samuel Nobs is an Assistant Professor and Group Leader at the Institute for Research in Biomedicine in Switzerland. He discusses how microbes in the lungs and gut may shape respiratory immunity and influence susceptibility to infections and chronic lung diseases. He highlights his lab's work to uncover the mechanisms behind these interactions using microbiome analysis and advanced experimental models. Featured Products and Resources: Download a practical guide on everything you need to know about cell isolation techniques. Download a free wallchart on the production of CAR T cells. The Immunology Science Round Up Rabbit Immunity Evolves – Wild rabbits rapidly evolved resistance to myxoma virus through changes in highly diverse MHC immune genes. Antifungal Receptors Improve Vaccines – Targeting antifungal immune receptors with a mannan-based adjuvant boosts the strength, durability, and variant coverage of mRNA vaccine responses. Mapping Tumor Macrophage Diversity – Scientists have revealed how diverse tumor-associated macrophage subtypes promote tumor growth, immune suppression, and metastasis through interactions within the tumor microenvironment. Dietary Soy Shapes Immunity – Dietary soy shapes the gut microbiome to boost IgA-mediated immunity and enhance protection against intestinal infection in early life. Image courtesy of Dr. Samuel Nobs. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe
Martín Letelier vuelve de París con polerita oficial, raqueta, mochila llena de stickers y una experiencia para contar de pe a pa. Felipe conduce y se transforma en oyente privilegiado mientras Martín relata su primer Grand Slam: el "Disneyland del tenis", el ballotage de Roland Garros, las entradas de 34 euros (sí, leíste bien), el ground pass que te deja entrar a Philippe Chatrier si no está lleno, la estatua de Nadal en la entrada con las 14 finales grabadas, y la batalla épica de gritos entre la dupla francesa y los pocos chilenos en una cancha auxiliar viendo a Tabilo jugar dobles.Después hablamos de tenis. La amarga derrota de Tabilo contra Félix en octavos, la baja providencial de Vacherot que abrió el camino, y la polémica con Séptimo Game cuestionando que Tabilo jugara dobles el día anterior (Martín le rebate punto por punto). La caída de Sinner con la teoría caballerosa de Martín, "la final del mundo" Djokovic vs Fonseca y la confianza que se construye al ganarle a un grande, el regreso anunciado de Serena Williams a los 46, las notas de Caterina con Sabalenka como favorita clara, Iga eliminada y la promesa de Marta Kostiuk.Y la evaluación de los cuartos de final pronosticados: la sección 1 fue un desastre total (¿alguien tenía a Berrettini vs Arnaldi?), la sección 2 cumplió con Félix vs Cobolli, en la sección 3 nos jugamos a Fonseca vs Mensik y en la sección 4 acertamos con Zverev vs Jodar (con la triste vuelta a la realidad del español). Cierre con la pregunta del millón: ¿quién gana este Roland Garros tan abierto?Síguenos en Instagram @lucklosers_podcast Twitter @LuckyLoserscast @luckyloserstenis Youtube https://www.youtube.com/@luckyloserspodcast8246
Jeff and Jim recap their week at KuppingerCole's EIC 2026 in Berlin, covering standout keynotes, hallway conversations, and sessions on securing AI agents, CIAM, and AI versus nuclear regulation. They announce a giveaway of Eve Maler's signed copy of Mastering Digital Identity for YouTube commenters by June 12th. The episode also features live footage and a full interview with Espen Bago, founder of Identibeer, recorded at the Berlin event. Jeff, Jim, and Espen discuss the rapid global growth of the Identibeer community, terminology challenges around NHI and IAM concepts, the gap between conference talk and real client needs, and why the industry keeps bypassing foundational data work in the rush toward AI and agentic identity.Connect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at http://idacpodcast.com00:00:10 Welcome and EIC 2026 Setup00:03:57 Eve Maler Book Giveaway Details00:05:00 Conference Highlights: Keynotes and Hallway Con00:06:07 Elizabeth Garber's Standing Ovation Keynote00:07:02 Brazil Invitation and Securing AI Agents00:09:10 Nuclear Regulation vs. AI Regulation00:11:07 Upcoming EIC Episode Preview00:14:16 Identibeer Berlin Live Event00:14:29 Interview with Espen Bago Begins00:15:14 Identibeer Growth and Global Expansion00:17:23 The Identibeer Name Debate00:23:26 Data Quality Gaps in NHI and IAM00:26:31 Who Owns IAM Terminology?00:34:20 Conference Talk vs. Client Reality00:40:52 The HR-IAM Gap Nobody Talks About00:43:17 Fundamentals: The Karate Kid AnalogyKeywords: EIC 2026, European Identity Conference, Identibeer, Espen Bago, Eve Maler, Elizabeth Garber, Mastering Digital Identity, Berlin, Identiverse, NHI, non-human identities, IAM fundamentals, AI regulation, agentic identity, IGA, PAM, CIAM, IDPro, identity community, IDAC, Identity at the Center, Jeff Steadman, Jim McDonald
Send us Fan MailWeek 1 of Roland Garros delivered pure unhinged energy, and Resh and Stef were SCREAMING — recording live together in San Francisco for the first time in two years. The biggest WTA story? Clayomi. Naomi Osaka walked out in a Germanier x Nike couture collab ("I look like the Eiffel Tower at night"), made it to the fourth round for the first time in her Roland Garros career, and co-hosted an invite-only Black Party at Soho House Paris with Taylor Townsend. She's serving on and off the court, and the haters (hi, Laura Siegemund) can sit down. Meanwhile, Resh's pick Coco Gauff — the defending champion — lost a gut-punch third-rounder to Potapova, Hailey Baptiste went down with ACL and meniscus injuries at her career peak, and Victoria Mboko broke our hearts in a three-setter against Madison Keys. Also: it sounds like Serena Williams may be coming back to tennis as soon as next week. This is not a drill.On the men's side, the Chaos Slam claimed its biggest victim when top seed Jannik Sinner — up two sets and 5-1 — melted in the sun and lost to the less known Cerundolo in five. The sun remains undefeated. Bright spots: 21-year-old Stanford data science student Nishesh Basavareddy upset 7-seed Taylor Fritz with cold-blooded drop shots, 17-year-old Moïse Kwame became the youngest player to win a Roland Garros match since 1991 (his prize money is locked in a bank until his 18th birthday, because France), and João Fonseca closed out a five-set win over Djokovic on three straight aces like it was nothing.We also need to talk about ATP player Adolfo Daniel Vallejo, who blamed his loss on female umpire Ana Carvalho — a silver badge professional and one of the best in the world — claiming she lacked the "strength" to handle the crowd. Roland Garros fined him and issued a statement. We revisit the Hurkacz 2024 incident, the Fognini 2017 incident, and note that Roland Garros's allyship would land harder if women's matches were ever scheduled in prime time. Heading into week 2: Sabalenka and Iga are the top contenders (despite the hosts' predictions), the Ukrainian sweep is still mathematically alive, and Naomi faces Sabalenka in what is absolutely must-watch Monday tennis.Support the showInstagram : Out_Wide_PodcastJingle : https://www.nelaruizcomposer.com/Logo: https://www.instagram.com/crayonspaghetti/
W dzisiejszym magazynie sportowym: Paris Saint Germaine zwycięzcą Ligi Mistrzów, Polska reszta Świata 3:0 oraz Iga Świątek odpada w czwartej rundzie French Open...Posłuchaj audycji radiowej w dowolnym czasie, naciśnij tutajSłuchaj audycji radia SBS Polish na żywo w poniedziałki, środy, czwartki, piątki i niedziele o godz. 14.00 (czasu wschodnioaustralijskiego) na paśmie SBS Radio 1 (Audycja czwartkowa jest powtarzana w niedzielę o godz. 14.00)Aby słuchać w radiu analogowym znajdź pasmo SBS Radio 1 naciskając link: Pasmo nadawania audycji w Twoim mieście naciśnij tutajAby słuchać w radiu cyfrowym DAB znajdź 'SBS Radio1'Aby słuchać w telewizji cyfrowej znajdź: SBS Radio 1 na kanale 301Aby słuchać w internecie wejdź na stronę: sbs.com.au/polishalbo naciśnij: Polskie Radio SBS i PodcastyAby sluchać w Twoim telefonie przez aplikację - zainstaluj bezpłatną aplikację SBS Audio App
John, Sam, Stevie, and special guest Caroline Wozniacki react to one of the biggest matches of the year as João Fonseca takes down Novak Djokovic in a five set thriller at Roland Garros. The gang breaks down Fonseca's incredible comeback, Djokovic's stunning five set record, and whether the draw is now wide open for a first time Grand Slam champion.Meanwhile, Casper Ruud survives Tommy Paul in another five setter, Zverev suddenly finds himself carrying favorite pressure, and the guys debate who's left standing in a draw that has completely exploded over the past few days.On the women's side, Coco Gauff crashes out against Potapova, Iga Swiątek starts looking like vintage Iga again, and the crew closes with Round of 16 predictions, and one final argument over whether they could score a penalty kick against a Champions League goalkeeper.00:00 We're Back!02:32 New Slam Champion Incoming03:00 Fonseca Stuns Djokovic06:50 Novak Praise and Big Stats12:27 Ruud Survives Tommy Paul15:19 Michelsen vs Jodar Drama18:40 Mens Draw Wide Open 19:31 Svajda Story and Cerundolo Bad x Good Brother Debate22:15 Zverev Pressure and Other Results26:16 Womens Draw 28:13 Gauff Match Breakdown30:33 Other Seeds Rolling31:24 Another Upset Analysis32:57 Cirstea Double Bagel34:02 Round Of 16 Picks37:10 Bracket Challenge & Champions League Penalties Debate39:44 Goodbye
How to Interpret Paediatric Microbiome Testing Correctly (and What Most Parents Aren't Told)This week on the Natural Super Kids Podcast, we're talking about one of the biggest issues we are seeing in children's health right now, the misinterpretation of paediatric microbiome testing.With more families turning to gut microbiome testing to understand eczema, allergies, digestive symptoms, immune issues, and overall health, it's becoming increasingly important for parents to understand that children's microbiome results cannot be interpreted the same way as adults'.We share key insights from a recent paediatric microbiome mentoring program with Dr Brad Leech. During this, Dr Brad explained the common mistakes that can lead to unnecessary supplementation, restrictive diets, and incorrect “leaky gut” diagnoses in children, which we wanted to share with you today.In this episode, we explore:Why most microbiome tests for kids use adult reference ranges that may not apply to childrenThe truth about zonulin, secretory IgA, and microbiome diversity scores in kids under 12Why a child's age, diet, breastfeeding history, and immune development matter when interpreting resultsHow the right practitioner and the right testing technology can make a huge difference in getting useful, accurate information
Iga Świątek beat compatriot Magda Linette 6-4 6-4 in 85 minutes to reach the Roland-Garros round of 16 for the eighth straight year, the first woman to do it since Monica Seles. Swiatek will play Marta Kostyuk next, who is on a 14-match winning streak. Who wins this clash? Learn more about your ad choices. Visit podcastchoices.com/adchoices
Jeff and Jim are back with the May 2026 mailbag, answering listener questions from Amsterdam, Mumbai, Austin, and Berlin. Topics include navigating IAM vendor acquisitions, defending against AI deepfakes in remote onboarding, governing contractor and third-party identities, fixing the leaver process in IGA, and tackling a decade of IAM technical debt. The episode closes with unpopular industry opinions: why RFPs are procurement theater, why rip and replace should be normalized, and why one-throat-to-choke vendor thinking usually backfires.IDPro new member discount: https://idpro.org/idac/Connect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at http://idacpodcast.comCHAPTER TIMESTAMPS00:00 Intro and SNL nostalgia03:25 AI model roundup: ChatGPT, Claude, Gemini, and usage limits10:16 Identiverse 2026 and IDPro member discount14:53 Q1: Navigating vendor acquisitions (Isabelle, Amsterdam)24:00 Q2: AI deepfakes in identity verification (Rajan, Mumbai)32:32 Q3: Contractor and third-party identity governance (Caleb, Austin)43:00 Q4: The leaver process and IGA scope gaps (Anonymous)51:10 Q5: Tackling IAM technical debt (Tomas, Berlin)57:00 Normalizing rip and replace01:01:00 RFPs, one throat to choke, and other hot takes01:08:00 Wrap-upKEYWORDSIAM, identity governance, IGA, vendor consolidation, acquisitions, deepfakes, identity verification, contractor management, non-employee identity, technical debt, rip and replace, RFP, joiner mover leaver, leaver process, Identiverse 2026, IDPro, IDAC, Identity at the Center, Jeff Steadman, Jim McDonald
The draw is out, Paris is heating up, and Ground Pass is back with a full Roland Garros 2026 preview. Anastasia and Nick break down a lopsided men's draw where most of the drama lives in the bottom half, a wide-open women's draw with at least fifteen real title contenders, and the section of the bracket where Iga Świątek and Novak Djokovic both drew the worst possible neighborhoods.We get into Carlos Alcaraz's grass-season pullout (and yes, that Vanity Fair cover), the players we're watching from the top of the field down to the qualifiers, the wild card storyline we've been tracking all year in Akasha Urhobo, and the first-round matches we're refusing to miss, including a bold upset call on Aryna Sabalenka in round one.Plus: dates for our McCarran Park screenings, how to join the Ground Pass crew in the Served Bracket Challenge, the launch of our daily Coffee Catch-Up newsletter for the fortnight, and Nick reading a tennis match report from 1878 that you have to hear to believe.Players covered include Arthur Fils, Mirra Andreeva, Casper Ruud, Linda Nosková, Rafael Jodar, Lilli Tagger, Elina Svitolina, Flavio Cobolli, Hailey Baptiste, Eliot Spizzirri, Frances Tiafoe, Taylor Fritz, Nishesh Basavareddy, Kaitlin Quevedo, Emilio Nava, Michael Zheng, Toby Samuel, and Akasha Urhobo.Chapters:00:00 Weather and Merch: A Warm Welcome03:19 Carlos Alcaraz's Withdrawal from Wimbledon07:47 Thoughts on the Roland Garros Draw Ceremony11:00 Join us for the Served Bracket Challenge13:44 McCarren park Screenings details15:14 Draw Analysis: Men's and Women's Perspectives19:27 Players to Watch: Rising Stars and Dark Horses34:28 Qualifiers to watch39:00 Spotlight on Qualifiers: Rising Stars40:46 Wild Cards and Their Potential44:13 Our interview with Akasha Urhobo53:10 Exciting Matches to Watch: First Round Highlights59:02 Roland-Garros Updates: What to Expect01:04:28 Tennis History: A Look Back [Outro]Links:Send us a voice memo: https://www.groundpasspodcast.com/voice-memoAthletic story about Alcaraz injury [Gift Link]: https://www.nytimes.com/athletic/7263807/2026/05/20/tennis-worst-injury-wrist-recovery-treatment/?source=user_shared_article&unlocked_article_code=1.klA.BuEf.htnlRpDbLNVVRoland Garros Draw: https://www.groundpasspodcast.com/guides/rolandgarros2026printabledrawsServed Bracket Challenge: https://served.bracket.tennis
As The Body Serve heads to Paris for the first time, here's our preview of the 2026 edition of Roland Garros, where Jannik Sinner seeks to make more history and a number of top women find themselves in position to snatch. As usual, we take you through both draws: a surprisingly balanced women's draw (except for Iga -- sorry, girl) and a men's draw with not much intrigue, at least on the surface. The players associated with Project Red Eye have staged a work-to-rule labour action, refusing rightsholder interviews and committing only 15 minutes to pre-tournament media activities. Also, the federal judge in the PTPA case couldn't order Wimbledon and the French to give up those coveted press credentials. I guess they're stuck buying tickets like everybody else! 1:05 Qualifiers: Sloane through; Plishy & Greg are not :( 4:45 This week: Casper, rest! 7:20 Women's draw 20:20 Men's draw 39:55 PTPA credentials drama: judge says it's petty but what can I do, babes 42:50 Players stage a labour action! 49:05 Stevie Wonder, randomly
Jimmy and Brett are back after a short hiatus to preview Roland Garros 2026. Can anyone stop Jannik Sinner from completing the career grand slam? Can Djoker win major #25? Will someone new make a run to the finals? The women's draw is much more wide open then the men. Can Coco repeat? Will Sabby get revenge for last year? Will we get another Iga vs Ostapenko matchup? So many great storylines on the women's side. Jimmy answers some of your questions on a brand new Advantage Connors podcast! Follow us on - Twitter - @AdvConnors @JimmyConnors @Brett_Connors Instagram - @AdvConnors @Bretterz @GolddoodIsabella Facebook - Jimmy Connors official Facebook page Leave your questions/topics/or links to stories you want us to talk about next week on Jimmy's official Facebook page. Learn more about your ad choices. Visit megaphone.fm/adchoices
John, Sam, and Stevie officially enter Roland-Garros mode, where one question takes over the entire men's draw: can anyone stop Jannik Sinner? The guys make their picks, debate why Novak Djokovic somehow keeps showing up near the top of the odds board, throw out dark horses, and come up with increasingly ridiculous theories for how Sinner could actually lose.On the women's side, nobody agrees on anything. Iga, Sabalenka, Coco, Rybakina — the board turns into complete chaos as the guys make title picks, argue over who's being underrated, and try to figure out whether taking “the field” might be the safest bet.Plus: Most Beautiful Courts returns with absurd tennis postcard locations, and things completely derail during an overrated TV show draft featuring Yellowstone, Friends, Stranger Things, airport breakfast outrage, and several takes that may age worse than the Roland-Garros predictions.--French Open Bracket Draw is now live! And we are doing a draw for both the men & women. Submit yours to win some amazing Nothing Major prizes! https://bracket.nothingmajorshow.com/nothingmajor
Hydrogen water—breakthrough or scam? Osteoporosis fixes; Nattokinase for cardiovascular prevention; Why vitamin D helps a subset of diabetics; When oral vitamin D doesn't work, sublingual D may normalize blood levels; Vitamin D found beneficial for colitis; Why fructose stokes food cravings; Flawed fluoridation study claims no IQ harms to kids.
W dzisiejszym magazynie sportowym: Iga Świątek w półfinale turnieju w Rzymie; Lech Poznań mistrzem na kolejkę przed zakończeniem rozgrywek piłkarskiej ekstraklasy; zwycięstwo Polaka w wyścigu Indianapolis...
In the final episode, Pranav Garimella explores glomerular and cystic kidney diseases, including IgA nephropathy and autosomal dominant polycystic kidney disease. Discover how personalised medicine, biomarkers, and earlier diagnosis are shaping the future of care in these complex conditions. Timestamps: 01:11 – Current treatment for IgA nephropathy 02:24 – SGLT2 inhibitors 03:38 – Cystic kidney disease diagnosis
4x Grand Slam champion Kim Clijsters and tennis reporter Blair Henley are joined by WTA pro and model Carson Branstine to discuss the realities of life on tour outside the top 100. Carson, currently recovering from a torn labrum, opens up about funding her career without a coach or physio, her viral TikTok calling out player welfare failures, and how she balances tennis with modeling and a new finance venture. Kim adds perspective from her time on the WTA board and her own battles with the tour's injury fine system. Kim and Blair also break down a busy week in Rome: Sorana Cirstea beating Sabalenka at 36 years old and reconsidering her retirement and Coco Gauff's admission of off-court struggles. They also weigh in on Project Red Eye, the player-led push for greater Grand Slam revenue sharing, and the story of Ukrainian player Oleksandra Oliynykova, who is using her platform to raise funds for the Ukrainian military. Kim closes with a tactical breakdown of Iga Swiatek's backhand slice, explaining why it has become one of the most effective weapons on tour heading into Roland Garros. Welcome to Love All! If you want to hang out with us behind the scenes follow us on all of our socials: https://www.instagram.com/loveallpodcast/ https://www.tiktok.com/@loveallpodcast https://x.com/loveallpodcast ' Kim's Recs Mouth Tape: https://zippit.nl/en/products/mouth-tape?shpxid=6de1bfcf-6ccc-45df-81f6-c3866e134212 Powder SPF: https://www.nomige.com/en/pages/leeray?srsltid=AfmBOoqztTF81pHzn42YLvMfTi3r66QSCxEpBvuZY26Q-9wmEN9j1Og3 Blair's Rec SPF Setting Spray https://www.onesizebeauty.com/products/on-til-dawn-mattifying-sunscreen-makeup-setting-spray-spf-28-full?srsltid=AfmBOorYde4DM29IipIoN4yJZqGzsR5_8PeRY3XihUDevWe_f1odVst6&variant=45363114574023 ⏰ TIMESTAMPS: 0:00: Welcome to Love All 1:09: Carson Branstine joins Love All 3:02: Carson on Kim Clijsters as her idol & inspiration to play tennis 5:28: Injury update 8:29: Carson's life off court 11:28: Carson's viral TikTok: The realities of life on the WTA tour 13:54: Reaction to the TikTok 18:51: Kim & Carson on player costs, prize money & the financial grind of pro tennis 25:02: Can you have quality of life and compete at the highest level in tennis? 35:22: Henley's Headlines: Rome Open update & Sorana Cîrstea's retirement year story 44:13: Aryna Sabalenka's form heading into Roland Garros 45:55: Coco Gauff's emotional struggles 51:03: Oleksandra Oliynikova: Using her platform to support Ukraine & challenging the WTA 59:09: Kim-formation: Iga Świątek's renewed joy with coach Francisco Roig 1:01:40: Iga's backhand tactics against Osaka 1:04:16: Francisco Roig ruptures his Achilles at practice & returns immediately 1:07:15: Holger Rune skips Roland Garros to protect his Achilles recovery 1:08:42: Rec Room: Mouth tape, SPF setting spray & brush-on sunscreen 1:14:07: Closing thoughts Learn more about your ad choices. Visit megaphone.fm/adchoices
Functional Diagnostic Nutrition: Using Saliva Testing, Food Sensitivity Labs, and Lifestyle to Find Root Causes: Reed Davis, Board Certified Holistic Health Practitioner (HHP) and Certified Nutritional Therapist (CNT), is founder of Functional Diagnostic Nutrition (FDN). He discusses using functional testing alongside conventional care to uncover “dysfunction” when standard labs appear normal. Davis describes assessing adrenal and metabolic stress via saliva testing for circadian cortisol patterns, cortisol-DHEA balance, sex hormones, secretory IgA, and melatonin, emphasizing clinical correlation and individualized “studies of one.” He outlines an approach targeting multiple “healing opportunities” (H-I-D-D-E-N: hormones, immune, digestion, detoxification, energy, nervous system) and applying D-R-E-S-S (diet, rest, exercise, stress reduction, supplementation) rather than relying on supplements alone. A case example links chronic hives, medication-related weight gain, and food triggers identified through additional testing, including the Mediator Release Test. The discussion also covers stress-driven gut dysbiosis, digestion decline, and EFT tapping for stress-related symptoms, and notes FDN practitioners can be found via FDNtraining.com/medicine.
Luc Dupont analyse les plus récentes données de Comscore sur les usages numériques au Canada, qui montrent une hausse généralisée de l'utilisation d'Internet sur téléphone intelligent, tablette et ordinateur. La vidéo domine désormais la consommation d'actualité, notamment sur YouTube, tandis que l'audio progresse fortement avec Spotify. L'étude révèle aussi des comportements plus marqués selon les générations, avec TikTok et Snapchat chez les jeunes, alors que les plus âgés privilégient Facebook, Google Maps ou les services météo. Du côté du commerce en ligne, Amazon domine largement, suivi notamment de Temu, Walmart et des acteurs canadiens comme Canadian Tire et IGA. Enfin, l'intelligence artificielle commence déjà à redéfinir les usages numériques, avec OpenAI et son outil ChatGPT qui s'imposent comme référence auprès du grand public.
Odcinek z wideo na dostępnym na YouTube. Iga na urlopie, więc zastępuje ją godnie Adam Piechota – człowiek wykształcony i kształcący. W tym odcinku wszyscy jesteśmy z młodzieżą, ale ze starszą młodzieżą, taką co to tęsknie wspomina X360, lata 90. i retrofuturyzm spod znaku Cyberpunka 2020. Dlatego w CJG przedstawiamy wam: Z kolei w sekcji […]
W dzisiejszym magazynie sportowym: Iga Świątek jedyną Polką w trzeciej rundzie w Rzymie; zacięta rywalizacja w końcówce polskiej ekstraklasy piłkarskiej; czwarte miejsce reprezentacji Polski w hokeju na lodzie na mistrzostwach świata w Sosnowcu.
IgA nephropathy and IgA vasculitis remain complex and evolving areas in nephrology care. In this episode, experts discuss key insights from the KDIGO guidelines and KDOQI commentary published in AJKD, focusing on updated approaches to risk stratification, disease progression, and treatment decision making. The conversation highlights the role of supportive care, immunosuppressive therapy considerations, and emerging therapeutic options, while addressing variability in clinical practice and patient management challenges. This episode provides practical, evidence based perspectives to help clinicians navigate the nuances of IgAN and IgAV care and apply guideline recommendations in real world settings. Please view the AJKD article here.
Send me a text! I'd LOVE to hear your feedback on this episode!You've probably been told your appendix and tonsils are basically optional. I don't buy that — and the research backs me up.In this episode I break down the full story on two of the most dismissed organs in the body. What they actually do, why they matter more than you've been told, what drives removal, and what can shift afterward — plus how to support yourself whether you still have them or not.Your appendix is an active microbiome reservoir that helps reseed your gut after illness, infection, or antibiotics, and plays a direct role in IgA immune regulation. Your tonsils are your immune system's first line of defense — tied to your oral microbiome, lymphatic drainage, airway mechanics, and vagus nerve tone. These are not evolutionary leftovers. They are functional, living parts of systems your body depends on daily.I cover what actually drives appendicitis and tonsil failure, the connection to dysbiosis and chronic inflammation, and what people notice after removal — gut reactivity, anxiety, shifted gut-brain signaling, and immune changes. I also walk through the practical tools that support your body on both sides — fibre, prebiotics, polyphenols, gut barrier support, warm salt water gargling, nasal breathing, tongue posture, anti-inflammatory nutrition, hydration, and nervous system regulation.I also explore the somatic and energetic layer — safety and intuition with the appendix, and voice, truth, and boundaries with the tonsils. Science and soul, together.This is Part 2 of 2. Part 1 covers the gallbladder and uterus — two more organs dismissed as optional that your body would strongly disagree with. Listen to Part 1 here: https://podcasts.apple.com/ca/podcaJoin here: Sandy K Inner Circle Join me here: Sandy K Inner CircleSupport the showJoin The Sandy K Inner Circle -- my private women-only subscription community where we go deeper than the podcast ever could.Every month you get:A live Q&A with Sandy on ZoomAn exclusive podcast episode nobody else hearsA practical curated downloadAccess to our private women-only Facebook community for wide open discussions on all topicsNo agendas. No noise. No bias. No trendy health advice from those who pay for their platforms. No medical advice. Real conversations you will not find anywhere else.Founding member spots are limited at $47 CAD/month.Join us here: sandykruse.substack.comFor women only. By invitation.Instagram: https://www.instagram.com/sandyknutrition/Facebook Page: https://www.facebook.com/sandyknutritionTikTok: https://www.tiktok.com/@sandyknutritionYouTube: https://www.youtube.com/channel/UCIh48ov-SgbSUXsVeLL2qAgRumble: https://rumble.com/c/c-5461001Linkedin: ...
Recorded live as part of the Identity Management Day 2026 streaming program, Jeff and Jim mark their fifth IMD episode. Introduced by Jeff Reich from the Identity Defined Security Alliance, they reflect on how the IAM industry has evolved since their first IMD episode in 2021 and grade overall progress a C. Topics include what has genuinely improved (passkeys, MFA adoption, broader awareness), what hasn't (compliance fatigue, security theater, persistent credential theft), the exploding challenge of non-human identity governance, whether AI will eventually need to certify other AI, and how AI-powered phishing and deep fakes are raising the bar for identity verification. The episode wraps with chat-submitted IAM bumper stickers.Identity Management Day 2026: https://www.idsalliance.org/event/identity-management-day-2026/Connect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at http://idacpodcast.comCHAPTERS0:00 - Jeff Reich intro from the IMD stream2:00 - Identity Management Day 2026 kicks off3:30 - Five years of IMD: a look back at episode 887:00 - Does IMD move the needle?9:30 - Who is Identity Management Day actually for?12:00 - What has improved in IAM over five years16:00 - What hasn't improved: compliance fatigue and security theater18:30 - Grading the IAM industry21:00 - NHI governance: visibility and accountability26:00 - Can AI certify AI? Agentic identity governance29:00 - AI-powered phishing and the evolving threat landscape32:00 - Deep fakes and the identity verification challenge36:00 - Lighter note: IAM bumper stickersKEYWORDSidentity management day, identity management day 2026, NHI, non-human identity, agentic AI, phishing, deep fakes, IGA, passkeys, MFA, IAM, identity governance, access management, cybersecurity, credential theft, security awareness, IDAC, Identity at the Center, Jeff Steadman, Jim McDonald
#317 I'm a degree-qualified naturopath with over 20 years of clinical experience, with a primary focus on complex gut health conditions — and in this video, I'm doing something I've never done before. I'm turning the lens on myself. I recently got my own gut microbiome tested, and I want to walk you through every single result. I didn't get tested because I had gut symptoms — my bowels are actually moving beautifully. I got tested because I'd been dealing with over a year of persistent rosacea and wanted to know: could what's happening in my gut be connected to what's showing up on my skin? I also wanted to show you exactly what this test looks like when it's interpreted by someone who does this for a living. We cover every section of the report — the pathogen panel, the diagnostic GI markers, microbiome diversity and richness, short-chain fatty acids, TMA, emerging metabolites, the species table, and more. I also share the result that was flagged as severely abnormal — and why, in context, it almost certainly isn't. This is what it looks like to use real data to motivate real change — not because something has gone terribly wrong, but because catching the trajectory early is the whole point. What we cover What makes shotgun metagenomics different from other stool tests The targeted pathogen panel — what it tests for and what my results showed Pancreatic elastase — the result that flagged severely low, and why context changes everything Lactoferrin, calprotectin, zonulin, secretory IgA, and faecal occult blood Microbial diversity and richness — what we're aiming for and why it matters Butyrate, acetate, propionate, and TMA — what they mean and how diet influences them Prevotella copri — nuanced, misunderstood, and more common in traditional diets than you'd think Emerging markers, including GABA, and why we need to hold them lightly Human DNA elevation — and why collection context explains it My action steps and why seeing this data now motivates me to act I'm Lynda Griparic, a degree-qualified naturopath with extensive experience in complex gut health conditions, including SIBO, IMO, and chronic constipation. Book a consultation or shop BetterMe Tea at lyndagriparic.com This content is for educational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health routine.
Whether it was bad shrimp or a virus, the outcome – or the output, rather – was the same. Week one of Madrid was rocked by player illness and withdrawals, with Iga retiring for only the second time in her career and Coco getting sick on court before pulling through against Cirstea. We take a scattershot approach to Madrid, highlighting Pliskova, Jodar, and Grant (and a few lowlights). Plus, we take an extended look at electronic line calling on clay, the untrustworthiness of ball marks, and the imperfections and idiosyncrasies of tennis that make the sport sing. We finish up with some offcourt news – including the surprising departure of the WTA's CEO – plus rapid-fire listener questions. 1:40 Carlos is out of Rome and Roland Garros 4:35 Virus or food poisoning … either way, the players were sick as dogs 11:40 Plisko, Naomi, Tyra Grant, Rafa J 21:05 Alex and Grigor down bad, Stefanos crashing out but actually winning 26:20 Electronic line calling on clay: the ball mark isn't as clear-cut as you'd think 35:15 Maria Sharapova is in the podcast business 38:15 WTA CEO Portia Archer has resigned 40:35 The Fritz-Riddle breakup 43:55 A few listener questions
Exclusive $25-off Carver Mat at https://on.auraframes.com/NOTHINGMAJOR. Promo Code NOTHINGMAJORJohn Isner, Sam Querrey, and Steve Johnson open by celebrating 40,000 YouTube subscribers and teasing a new Wayne Bryan jingle. They then break down Madrid: Spanish teen Rafa Jodar becomes the tournament's main attraction with big wins, they note other men's results, Americans' struggles, and Tsitsipas showing signs of life, while Sinner stays on track and they discuss his potential record breaking streak. On the women's side they cover McNally over Mboko, Pegula's loss, American standouts, illness talk around “shrimp tacos,” concerns about Iga, and Sabalenka beating Osaka.Then they highlight a Real Madrid stadium hit, and react to the massive news of Carlos Alcaraz withdrawing from Roland Garros.00:00 Show Tease and Intro00:16 40K Subscribers Milestone02:07 Dealing With Negative Comments03:30 Sams Bet05:00 New Wayne Bryan Jingle05:53 Madrid Winners Circle Begins06:11 Rafa Jodar Breakout Story14:53 Other Madrid Men Highlights19:16 Americans Struggle in Madrid20:41 Tsitsipas Resurgence Talk23:39 Sinner Outlook and Rome Debate25:38 Madrid Women Updates26:57 Surprise Quarterfinalists27:22 Shrimp Taco Rumor28:20 Iga Panic Button29:24 Sabalenka Osaka Thriller29:58 Baptiste Racket Smash30:41 Eva Lys Pod Plans34:19 Bernabeu Tennis Crossover36:54 Alcaraz Out Of RG42:42 Fritz Breakup Talk44:14 Sinner's Streak47:04 Texting Time Etiquette47:46 College Tennis Crisis53:17 Wrap Up And Jingle
Want to be featured on the next Q&Andy? Send us a video on our socials or email us at askandy@servedmediagroup.com Andy Roddick sits down with rising star Iva Jovic for this episode of Q&Andy. Jovic offers direct advice for juniors turning pro, explains how she reframes pressure, and shares a court geometry tip from Novak Djokovic shaping her game. The episode includes a debate on Roger Federer's backhand volley vs. John Isner's serve, plus her view that the sport chooses you. They also break down Iga Świątek's dominance on clay and end with a funny question from an eight-year-old fan.
This bonus episode of Identity at the Center is brought to you with support from Elimity. Jeff and Jim sit down with Maarten Decat, co-founder and CEO of Elimity, to explore the emerging product category known as IVIP, Identity Visibility and Intelligence Platforms. Maarten explains how Elimity was built around a question every IAM practitioner eventually faces: who can actually do what within our organization? The conversation covers why IVIP is distinct from traditional IGA, how identity data graphs provide deeper visibility than flat entitlement lists, and what regulatory drivers like SOC 2, ISO 27001, and DORA are pushing organizations toward this space. They also discuss deployment patterns, integration approaches, ROI metrics for leadership, and what Maarten calls provable control. The episode closes with a memorable story about Elimity branded Belgian beer and a very formal legal letter. Learn more at elimity.com/idac.Connect with Maarten: https://www.linkedin.com/in/maartendecat/Learn more about Elimity: https://elimity.com/idacConnect with us on LinkedIn:Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/Visit the show on the web at idacpodcast.comCHAPTER TIMESTAMPS00:00 Introduction and ax-throwing memories from EIC Berlin01:35 Introducing Maarten Decat, co-founder and CEO of Elimity01:57 How identity chose Maarten: from PhD to startup founder03:09 The Elimity origin story and the problem it set out to solve04:52 Defining IVIP: Identity Visibility and Intelligence Platforms05:31 Where did the name Elimity come from?06:57 Why identity visibility has become a security priority now09:02 What organizations were doing before IVIP existed11:16 Can IGA do what IVIP does? Addressing the skeptics14:20 The identity data graph: deeper and wider than IGA16:20 IVIP and IGA as complementary tools, not competitors16:49 What falls outside IVIP scope: automated provisioning18:01 IVIP as the intelligence layer in your IAM stack19:45 What data sources connect into an IVIP platform21:44 Extending visibility to non-human identities22:00 M&A use cases: gaining visibility across two organizations23:55 IVIP and the identity fabric concept25:18 Visibility, intelligence, and actions: building the right stack26:36 How deployments typically start and what early wins look like28:44 Integration approaches and realistic effort timelines32:00 What success looks like at six to twelve months36:07 Metrics and ROI: talking to leadership about identity risk38:14 Case studies and customer examples on the Elimity website38:58 What every IAM practitioner should know about IVIP40:12 Elimity's global reach: EU, US, and Middle East41:42 The Elimity branded beer story and a very formal legal letter46:43 Wrap-up and final thoughtsKEYWORDSIVIP, identity visibility and intelligence platforms, IGA, identity governance, access control, identity data graph, Elimity, Maarten Decat, non-human identities, access risk, provable control, SOC 2, ISO 27001, DORA, CCPA, cybersecurity, PAM, IAM, identity and access management, EIC, IDAC, Identity at the Center, Jeff Steadman, Jim McDonald
Arthur Fils caps his successful comeback to the tour with the Barcelona crown, while official tennis outlets act h-word on main while they trade on his good looks. Ben Shelton wins his first clay title outside of Texas and marks a surprising milestone for US men. Clay queens Coco and Iga are down bad while Elena, Karolina, and Marta soar; and Carlos' status is questionable for who knows how long. Finally, we talk about the news that interests me most: Marketa Vondrousova has been charged with refusing to give a sample to a doping control officer. Her social media posts about the incident provide interesting context but – as we've seen before – could come back to bite. 2:15 Arthur Fils is the truth! 8:55 Rybakina wins Stuttgart again, Muchova exorcises some demons 14:00 Join Elena's crypto community … 18:35 Ben Shelton, American king of clay? 26:35 Vondrousova's case 37:40 James talks about books and takes another quiz!
In Monte Carlo, Sinner's 4th consecutive Master's title and reclaiming of the #1 ranking adds another wrinkle to the Sincaraz rivalry. We talk about our desire for a little less golden retriever energy from Carlos – or, at least one of us does – but ultimately an unfriendly rivalry is no longer advantageous for today's player brands. Last week, Pegula defended her Charleston title, 3 Argentines made 3 different finals, and Iga appeared at the Rafa Nadal Academy with her new coach Francisco Roig. We also talk about golf, double bagels, Coco having to defend herself online (again), and an intriguing FMK about three celebrated tennis careers. 1:05 Bestie rivals, a hallmark of this era 13:35 A double bagel to Berrettini, come on man 16:35 I thank myself 20:40 Coco defends her Miu Miu look and her hair from online waste yutes and losers 24:05 Pegula wins the first equalized 500 prize money in Charleston 29:10 Men's results last week: Tommy Paul, first career titles for Jodar and Navone 33:00 Coaching carousel 36:20 Rory McIlroy defends his Masters title; Caroline still has shooters 39:45 FMK Tennis careers: Sharapova, Hingis, Davenport