Podcasts about Iga

We react to Danielle Collins defeating Iga Swiatek 6-1 7-5 in the Rome Masters 3rd round . We also speak about the other results of both men's and women's events. Tell us your thoughts in the comments! ❤️ SUBSCRIBE TO GTL: https://bit.ly/35JyOhz ▶️ JOIN YOUTUBE MEMBERSHIP: https://bit.ly/3Fk9rSr

Madrid ends with Aryna Sabalenka further extending her lead as number one, Casper Ruud grabbing his first Masters, and a lot of discourse around Iga Swiatek, Coco Gauff, and Naomi Osaka. We've got updates on: Jannik Sinner's hero's welcome in Rome, Bianca Andreescu, Anastasija Sevastova, Tyra Grant, and more. We do a quick review of the strange but sometimes interesting Alcaraz Netflix documentary before wrapping the episode with a dive into the Max Purcell doping suspension, which is way more fascinating than he first let on.  Theme music courtesy of Oleg Fedak from Pixabay 01:45 Penko being Penko 5:05 Madrid: the Iga discourse  9:45 Sabalenka d. Gauff to win Madrid, joins the 11,000 points club  13:40 Casper wins his first Masters 1000 20:20 Osaka drops a level and wins!  23:15 Jannik, the ironic vir triumphalis, returns to Rome 26:15 Updates on Andreescu, Sevastova 30:20 The perplexing Alcaraz Netflix doc 40:00 Is Venus quiet quitting (or did she already)? 43:05 The Max Purcell doping case gets a lot more interesting

In this episode, we highlight vitamin D₃ in gastrointestinal health, with a focus on intestinal barrier function and the gut-immune axis. We discuss how vitamin D is metabolized into its active form, 1,25-dihydroxyvitamin D, and how 1,25-dihydroxyvitamin D can support the intestinal mucosa, while highlighting the intestinal epithelium and immune cells in the lamina propria. Through this, we further detail the role of regulatory T cells in supporting immune balance and modulating immune function.Topics:1. Introduction - Highlighting intestinal barrier function and the gut-immune axis with a focus on vitamin D₃ 2. Vitamin D Synthesis and Metabolism - Skin and 7-dehydrocholesterol; dietary intake.- Transported through the bloodstream bound to vitamin D binding protein.- First hydroxylation in the liver to form 25-hydroxyvitamin D₃ (25(OH)D₃).- Testing.- Second hydroxylation in the kidney to form the active 1,25 dihydroxyvitamin D₃ (1,25(OH)₂D₃).- Local activation also occurs. 3. Intestinal Barrier Anatomy - The intestinal epithelium forms a selectively permeable monolayer that interfaces with the gut lumen.- Covered by a mucus layer: mucins, antimicrobial peptides, secretory IgA.- Mucus layer provides physical and biochemical protection.- Tight junction proteins and paracellular permeability.- Molecules crossing the epithelium. - Disruption of tight junctions, immune cell exposure to luminal contents.- The lamina propria and Gut-Associated Lymphoid Tissue (GALT). - Maintaining tolerance while defending against pathogens.  4. Vitamin D's Role in Barrier Support and Immune Modulation - 1,25-dihydroxyvitamin D₃, tight junction integrity, immune regulation, and more.- Regulatory T Cells (Tregs) and immune balance.   5. Vitamin D₂ and D₃- D₃ (cholecalciferol) is more biologically effective and binds DBP more strongly.  6. Vitamin D Levels - Levels observed in autoimmune conditions, IBS, and more.- Symptoms.- Insufficient and excessive levels of vitamin D can be detrimental.- Multi-system.  7. Conclusion - Multifactorial: Numerous factors regulate vitamin D levels.- Gastrointestinal health root cause approach.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

In this episode, we're talking all things grassfed whey—a supplement we recommend to nearly every client for good reason. From weight loss and lean body mass to metabolic and immune health, the benefits of whey are powerful and broad spectrum. We break down what whey protein is, how it's made, and why we choose to use a whey concentrate over an isolate. We dive into the synergistic compounds found only in whey concentrates that are low heat processed like lactoferrin, CLA, and immunoglobulins—and how they go beyond muscle to support immune resilience, gut lining integrity, and even antioxidant production via glutathione synthesis. We're thrilled to unveil Whey Protect—our upgraded version of Naturally Nourished Grassfed Whey, now with added serum bovine immunoglobulins to further support immunity and reduce inflammation. We touch on how our formula stacks up in purity compared to mainstream brands and discuss the Clean Label Project's recent findings on heavy metals in popular protein powders. Plus, we share our favorite ways to incorporate Whey Protect into your daily routine for optimal health! Also in this episode:  Whey Protect Now Available - use code NN Whey for 15% off!  Episode 288: Whey Protein: lactoferrin, immunoglobulins, BCAAs and more!  Episode 368 What's up with Armra Colostrum? Serum Bovine Immunoglobulins vs. Colostrum What is whey and how is it made?  Comparing whey concentrate to whey isolate Compounds that make whey a superfood Immunoglobulins (IgG, IgA, IgM) – Immune Defense & Gut Health Lactoferrin – Iron-Binding Protein with Antimicrobial Power Glycomacropeptides (GMPs) – Gut & Brain Health Serum Albumin – Antioxidant & Detox Support Growth Factors (IGF-1, TGF-β) – Muscle Growth & Tissue Repair Why are are adding Serum Bovine Immunoglobulins to Whey Protect Gut Health & Leaky Gut Repair Immune System Resilience Detoxification & Inflammation Control Recovery from exercise induced stress Whey and muscle protein synthesis, workout recovery & fat loss Whey Protein Supplementation Enhances Whole Body Protein Metabolism and Performance Recovery after Resistance Exercise: A Double-Blind Crossover Study The Effect of Whey Protein Supplementation on the Temporal Recovery of Muscle Function Following Resistance Training: A Systematic Review and Meta-Analysis Inulin-type fructans and whey protein both modulate appetite but only fructans alter gut microbiota in adults with overweight/obesity: A randomized controlled trial - PubMed Cocoa and Whey Protein Differentially Affect Markers of Lipid and Glucose Metabolism and Satiety Effects of whey protein and resistance exercise on body composition: a meta-analysis of randomized controlled trials  Whey and antioxidant production Whey Protein Supplementation Improves Nutritional Status, Glutathione Levels, and Immune Function in Cancer Patients: A Randomized, Double-Blind Controlled Trial Concerns with heavy metal toxicity & why you don't need to worry about this with Whey Protect!  Lead and cadmium found in muscle-building protein powders, report says | CNN 2024-25 Protein Powder Category Report How to use Whey Protect Banana Bolt Smoothie Matcha Green Smoothie Cinnamon Almond Keto Shake Cherry Vanilla Nirvana Smoothie How to Make a Keto Protein Shake and The Importance of Protein Easy Keto Green Smoothie (with super foods!) What makes Whey Protect Superior? Grass-fed, low-heat whey concentrate → Preserves bioactive compounds Contains ImmunoLin® serum bovine immunoglobulins → Supports immunity & gut health Rich in cysteine & glutathione → Powerful antioxidant support Boosts muscle growth & recovery → High leucine for optimal muscle synthesis Clean, third-party tested → No heavy metals or contaminants Sponsors for this episode:  Whey Protect: introducing our new Grassfed Whey with added serum bovine immunoglobulins to meet your protein goals and protect the body against infection, toxins, and regulate inflammatory response!   We saw the demands with sales increase of our GI Immune Builder and wanted to incorporate the therapeutic benefits of immunoglobulins in a daily easy to use product that can be used for enhanced immune function, metabolic results, and gut health.   Our Grassfed Whey has always been a top selling product in the Naturally Nourished line due to our quality sourcing and low heat processing to retain antioxidants and beneficial immune compounds such as lactoferrin and immunoglobulins. We wanted to ensure when you take our whey that you are providing your body with a shield of defense against pathogens (bacteria, virus, parasites, mold), toxins, and oxidative stress. Meet Whey Protect, our reformulated and enhanced Naturally Nourished Grassfed Whey.   We've added 350mg serum bovine immunoglobulins to each scoop to ensure you and your family receive a clinical impact to Protect you while helping you reach your daily protein goals with ease.    You're just a scoop a-WHEY from: Muscle gains  Immune resilience Improved bone density Gut health Lower toxicity Enhanced antioxidant status Reduced inflammation Weight loss with satiety and appetite regulation   Added Value at no added cost! We are thrilled to offer you this amazing upgrade at the same price, plus save during our launch sale! Use the code NNWHEY for 15% off    This episode is sponsored by Wild Foods, a company that puts quality, sustainability, and health first in all of their products. They have everything from coffee to turmeric to medicinal mushrooms, and every single product is painstakingly sourced from small farms around the globe. They take their mission seriously to fix the broken food system, and believe real food is medicine. They've partnered with us to give you guys an exclusive discount, so use the code ALIMILLERRD for 12% off your order at WildFoods.co! 

W dzisiejszym magazynie sportowym: Iga Świątek w czwartej rundzie turnieju tenisowego w Madrycie; historyczny sukces nowozelandzkiego klubu Auckland FC w piłkarskich rozgrywkach A-League; Wojtek Szczęsny wraz ze swoim klubem FC Barcelona zdobywcą piłkarskiego Pucharu Króla w Hiszpanii.

This week's Legislative Update podcast is packed with everything you need to know as we near the end of the 2025 legislative session!

Vansh and Damian discuss yet another Iga Świątek loss against Jelena Ostapenko and Carlos Alcaraz making the Barcelona final.Follow us on YouTube or Apple Podcasts as well. Download the TennisONE APP for scores, stats, news, videos, player content, fan contests, and more (https://t1.app.link/Vansh)

Happy Easter from all of us at IASP!

Pour clore cette saison en beauté, Isabelle vous emmène en primeur dans la maison des Roses de Montréal, la première équipe professionnelle féminine de soccer au Québec qui fait ses débuts ce printemps dans la Super League du Nord.Deux invitées d'exception : Mégane Sauvé – Joueuse polyvalente, ancienne des Carabins et du Sporting de Lisbonne Gabrielle Lambert – Gardienne au parcours atypique qui a su percer en Europe par sa persévérance et sa confiance.Ensemble, elles nous parlent de : Jouer pro chez soi : un rêve devenu réalité ️ Deux parcours, deux routes vers l'élite Une connexion forte entre soccer et hockey Transmettre l'espoir à la nouvelle génération Ce qui les anime au quotidien Le soutien de figures inspirantes féminines Un moment Popcorn croustillant qui mets en lumière leur relation joueuse-entraineure.Un épisode rempli d'émotions, de rires et de complicité pour conclure la saison en beauté. Une belle rencontre avec deux athlètes qui incarnent la fierté d'un sport au féminin en pleine transformation.Le balado Femme d'Hockey présenté par IGA est diffusé les jeudis à 16h30 sur TVA Sports.Merci à nos partenaires IGA, La Cage, CCM Hockey,Trema Café, à notre équipe, à nos invité(e)s et à vous, fidèles auditeurs et auditrices, qui êtes là depuis 5 ans. Abonne-toi, like et partage pour encourager le sport au féminin Suivez-nous pour plus de contenu exclusif :Facebook : @femmedhockeyInstagram : @femmedhockey | @isa.ethierX : @isabelleethierSite web : femme.hockey

Selles #332 episoodis on külaliseks inspireeriv juhtimiscoach, joogaterapeut ja personalijuht Kaire Parve, kellega sukeldume sügavatesse teemadesse nagu vaimne vastupidavus, mõtete juhtimine, potentsiaali avastamine ja sisemine tasakaal. Räägime, miks on negatiivsed mõtted tihti tugevamad kui positiivsed, kuidas tulla toime muutustega, milline mõju on joogateraapial ja miks tuleb tõelist rõõmu ja rahu otsida enda seest. Kaire jagab praktilisi soovitusi, teravaid taipamisi ja elulisi kogemusi, mis puudutavad nii juhtimist kui isiklikku arengut. Kuula saadet ja saa teada, miks “givers give” ja kuidas “mitte teadmisest algab tegelikult õppimine.” Rohkem infot leiad: www.kaireparve.com

Yes, it's been a minute, but we're back to catch up on Monte Carlo, Charleston, and sadly yes, all the way back to Miami. The top men have utterly failed to capitalize on Sinner's mandatory vacation, while on the women's side, Sabalenka extends her rankings lead and Pegula snatches #3 with her strong start to the year. We've also got: Kasatkina's move to Australia, the top WTA and ATP players sending a letter to the Slams a few weeks after the PTPA lawsuit, a few listener questions, and more.  1:10 Monte Carlo updates: why, Grigor, why? 9:10 Charleston results 14:20 Miami: Eala stuns Iga, Aryna extends her lead 25:30 Don't count your chickens before they hatch  28:20 Dasha Kasatkina is now representing Australia  31:00 The players do love an epistle  37:20 Coaching and baby news 40:35 A listener question

The CPG Guys are joined by Michael La Kier, Vice President Brand Development at the Independent Grocers Alliance (IGA) the largest affiliation of independent grocers in the U.S. andaround the world, boasting 2,500 U.S. stores and 7,500+ globally. This episode was recorded at the 2025 Commerce Media Brand Summit produced by WB Research.Find Michael on LinkedIn at: https://www.linkedin.com/in/michaellakier/Find IGA on LinkedIn at: https://www.linkedin.com/company/iga-inc./Find IGA online at: https://www.iga.com/Michael answers these questions:What is the history of retail media at IGA and how can brands activate on it?How can independents help brands regain their volume through customer acquisition?How does IGA help its members with assortment planning?Why should all marketing efforts drive actions?How has IGA partnered with Instacart?CPG Guys Website: http://CPGguys.comFMCG Guys Website: http://FMCGguys.comCPG Scoop Website: http://CPGscoop.comRhea Raj's Website: http://rhearaj.comLara Raj in Katseye: https://www.katseye.world/WB Research: https://www.wbresearch.com/DISCLAIMER: The content in this podcast episode is provided for general informational purposes only. By listening to our episode, you understand that no information contained in this episode should be construed as advice from CPGGUYS, LLC or the individual author, hosts, or guests, nor is it intended to be a substitute for research on any subject matter. Reference to any specific product or entity does not constitute an endorsement or recommendation by CPGGUYS, LLC. The views expressed by guests are their own and their appearance on the program does not imply an endorsement of them or any entity they represent. CPGGUYS LLC expressly disclaims any and all liability or responsibility for any direct, indirect, incidental, special, consequential or other damages arising out of any individual's use of, reference to, or inability to use this podcast or the information we presented in this podcast.

Pour Ingrid Falaise, le sport n'est pas qu'un passe-temps, mais une manière d'exister, de se reconstruire, de créer des ponts avec l'autre. Derrière la comédienne, l'autrice et la conférencière engagée, se cache une femme profondément marquée par le sport et son impact dans la communauté. Plongez dans ce 130e épisode du balado Femme d'Hockey présenté par IGA, où Ingrid dévoile une facette méconnue d'elle-même : celle d'une passionnée de sport moteur d'inclusion.Dans cet épisode vibrant et sensible : -Le sport comme lien familial : Ingrid évoque son père avec qui elle partage de précieux souvenirs autour -Une enfance de casse-cou : Elle dévoile son parcours sportif marqué par l'audace, les défis et quelques fractures bien placées ! -Un plaidoyer pour le sport adapté : Grâce à la série Adaptés, elle milite pour rendre le sport accessibles à tous les enfants, peu importe leur condition. -Le sport au féminin, sans cliché : Entre mansplaining, inégalités historiques et pression d'apparence, Ingrid lève le voile sur des réalités trop souvent banalisées.-Ce qui nourrit sa passion : Le challenge, la nature, le dépassement de soi, la communauté et cette quête de liberté. -Un regard lucide sur les violences conjugales : Dix ans après Le Monstre, elle rappelle que la question n'est pas « pourquoi elle ne part pas », mais bien « pourquoi la violence ». -Un moment Popcorn qui marque : Une anecdote marquante qui nous rappelle combien les stéréotypes influencent notre société.Un épisode touchant, drôle, engagé et profondément humain. Une conversation sincère entre deux femmes qui souhaitent un monde plus inclusif. Le balado Femme d'Hockey est diffusé tous les jeudis à 16h30 sur TVA Sports Suivez-nous pour plus de contenu exclusif : Facebook : @femmedhockey Instagram : @femmedhockey | @isa.ethier X : @isabelleethier Site web : femme.hockeyMerci à nos partenaires IGA, La Cage et Trema Café Abonne-toi, like et partage pour ne rien manquer !

藥師健生活 【小大人健康節｜春季線上婦幼展】開跑囉！

Every spring, the MBA program at the William & Mary School of Business presents the Principled Achievement Award to a leader who best embraces and demonstrates the tenets of principled achievement. Previous winners include the head coach of the Buffalo Bills, Sean McDermott; and AnnaMaria DeSalva, global chairman of Burson, the global communication company. The Principled Achievement Award winner is the leader who values people, diversity of thought, empathy, humility, integrity and success. This year's winner is Michael Medline, CEO of Empire Company and Sobeys Inc – Canada's second largest retailer, whose key businesses include Sobeys, Safeway, IGA, and others. Medline joins us to discuss principled achievement, leadership, and how doing things the right way is the only way.  Learn how the Raymond A. Mason School of Business at William and Mary can help you and your organization develop your top talent through customized executive education and professional development programs. Visit us at www.wmleadership.com. Thank you for listening.

This episode features two very special guests from the Indiana Association of School Business Officials: Executive Director Dr. Scott Bowling and long-time IASBO lobbyist Denny Costerison. In this conversation, we tackle two important goals—first, to gain a clearer understanding of the Indiana State Budget and its impact on education, and second, to break down the role of property taxes in school funding and explore how Senate Bill 1 could bring changes in this area.

In this episode, we talk with Kristi, a powerhouse in narrative design who transitioned from a successful copywriting career just two years ago. Since then, she's shaped the stories of over six indie titles, led narrative efforts on AA-sized projects, and is now taking on her biggest challenge yet, co-founding Future Suit Games and earning a spot in IGA's prestigious Foundy program. Kristi shares her expertise on storytelling, studio building, and taking bold leaps in the game industry.Learn more about KristiLearn more about usJoin the next episode of the Indie Game Lunch Hour LIVE every Wednesday at 12pm EST on our Discord channel to answer your own burning questions and be immortalized in the recordings.

122: In today's episode, we are going to talk about preparing the gut for probiotics. A lot of people don't realize that we have to prepare and strengthen the gut before it's ready for probiotics, which I talk about a lot in my new book The Herbal Dog. Strengthening the glycocalyx and IGA builds a resistant gut barrier before introducing probiotics. This is especially true in sensitive or immune compromised individuals. Strengthening these allows for commensal bacteria, which is good bacteria, can actually stick to the gut wall. Tune in to learn how natural remedies can help strengthen your dog's gut, making it the perfect environment for probiotics to thrive and support their overall health. Sponsored by: Goodness Gracious Green Juju Fido's Bone Broth Check Out Rita: BUY THE HERBAL DOG Rita's Instagram Facebook Group My Courses My Website and Store Produced By: Drake Peterson

Justin Fris and Sam Jones discuss reasons why the Bullwinkel electorate will be one to watch at the upcoming federal election. Plus: Basil Zempilas elected leader of the WA Liberal Party; Approval for $25 million IGA shopping centre in South Hedland; Gold Road CEO speaks following $3.3bn bid by JV partner Gold Fields.

It's time for The Truth!Today, Sam and Dougie are looking at Alexander Isak, who is hot property right now after another stellar campaign with Newcastle United, which culminated in him firing them to Carabao Cup glory at Wembley on Sunday against Liverpool. Newcastle are absolutely adamant that their Swedish superstar is going nowhere - and so they should be - but that hasn't stopped the rumour mill going into overdrive about clubs interested in prying him away from Tyneside this summer. So we dig into the numbers, take a look at Newcastle's financial position, examine the words of the people in the know about their business model, and try to work out whether this is bluster or something more concrete. We also explore possible destinations for if Newcastle decided that they were going to cash in on their most profitable asset, talking about how Isak would fit at both Liverpool and Arsenal - who are both reported to be very interested - and some alternate options on the continent as well. So, will Alexander Isak continue to spearhead the Geordie renaissance as they work their way up the table? Or will his value, a big offer, and a desire to build out the squad mean that he will be playing football elsewhere next year? Well, The Truth is somewhere in the middle... And remember, if you'd like more from the Rank Squad, including extra podcasts every Monday and Friday (including our weekly Postbox taking a look at the whole weekend of football) and access to our brilliant Discord community, then why not join us here on Patreon?

Well, well, well, what do we have here? Have we entered the Mirra era? If you know us, you know we're not saying that, we just wanted to say Mirra era. Andreeva fashioned a Keys-esque run to the title in the desert, beating the same four players Madison did to win the AO from the fourth round onward...in the same order! We talk about Iga, we talk about Jack, and we field some more listener questions on TBS 375 02:15 The Mirra Era 12:19 The Conchita Effect 17:01 What's up with Iga? 26:28 Jack Draper arrives 37:34 Taking a question about Larry Ellison … 46:32 Finding joy in tennis when things outside of tennis are generally terrible  51:22 If tennis were played on only one surface, which would you keep? 53:38 RHOP and other Bravo musings 

In this episode of "Tennis Traverse," host Ivy Zhang delves into the Indian Wells tennis tournament, providing detailed analyses of both ATP and WTA matches. She highlights key performances and match dynamics, discussing notable players like Arthur Fils, Lorenzo Musetti, Grigor Dimitrov, Holger Rune, Stefanos Tsitsipas, Jack Draper, Carlos Alcaraz, Daniil Medvedev, and Ben Shelton. On the WTA side, Ivy focuses on Aryna Sabalenka, Madison Keys, Iga Swiatek, and Qinwen Zheng. Time stamps:Introduction to Indian Wells (00:00:00)ATP Round of 32 Matches (00:01:01)Arthur Fils vs. Lorenzo Musetti (00:01:01)Dimitrov vs. Monfils (00:02:23)Holger Rune vs. Stefanos Tsitsipas (00:03:41)Jack Draper vs. Taylor Fritz (00:04:53)Quarterfinals Overview (00:06:10)Cerundolo vs. Carlos Alcaraz (00:07:14)Ben Shelton vs. Jack Draper (00:08:26)Arthur Fils vs. Daniil Medvedev (00:09:28)Tallon Griekspoor vs. Holger Rune (00:12:03)Semifinals Predictions (00:13:15)Jack Draper vs. Carlos Alcaraz Predictions (00:14:33)Final Predictions (00:15:48)Clara Tauson vs. Mirra Andreeva (00:16:00)Belinda Bencic vs. Diana Shnaider (00:18:18)Mirra Andreeva vs. Rybakina (00:19:33)Svitolina vs. Pegula (00:20:39)Iga Swiatek vs. Karolina Muchova (00:21:52)Sabalenka's Performance (00:24:19)Match Conditions Impact (00:25:38)Andreeva vs. Svitolina (00:26:55)Iga's Revenge (00:27:30)Semifinal Analysis (00:28:00)Andreeva vs. Swiatek (00:29:13)Predictions for Upcoming Matches (00:30:42)Grigor Dimitrov vs. Gael Monfils: https://www.youtube.com/watch?v=j5tbmD2h528Holger Rune vs Stefanos Tsitsipas: https://www.youtube.com/watch?v=qLo2onoryyMTaylor Fritz vs. Jack Draper: https://www.youtube.com/watch?v=OZBmVOh4poIBen Shelton vs. Jack Draper: https://www.youtube.com/watch?v=JXT4ogy9XlwArthur Fils vs. Daniil Medvedev: https://www.youtube.com/watch?v=nqSmS8dl_qoClara Tauson vs. Mirra Andreeva: https://www.youtube.com/watch?v=NXBrCWY6edABelinda Bencic vs. Diana Shnaider: https://www.youtube.com/watch?v=WE2gR7ypx2cMirra Andreeva vs. Elena Rybakina: https://www.youtube.com/watch?v=cWRVHNov8I4Elina Svitolina vs. Jessica Pegula: https://www.youtube.com/watch?v=sEcVyuIL7QUKarolina Muchova vs. Iga Swiatek: https://www.youtube.com/watch?v=zy_1-iCKAuYCoco Gauff vs. Belinda Bencic: https://www.youtube.com/watch?v=sVN8Mk09CrIDonna Vekic vs. Madison Keys: https://www.youtube.com/watch?v=2wCSu0bMFcwIga Swiatek vs. Qinwen Zheng: https://www.youtube.com/watch?v=rLTLHXGAydMAryna Sabalenka vs. Madison Keys: https://www.youtube.com/watch?v=x2aHSiYrs28Mirra Andreeva vs. Iga Swiatek: https://www.youtube.com/watch?v=bPsKMtXRu8wSocial Media:Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/tennistraverse/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/tennistraverse⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@TennisTraverse/videos⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Linktree: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/tennistraverse⁠⁠⁠⁠⁠⁠⁠SUBSCRIBE TO MY NEWSLETTER:⁠⁠⁠⁠⁠⁠⁠⁠https://ivannazhang428.substack.com/

W dzisiejszym magazynie sportowym: Iga Świątek odpadła z tenisowego turnieju Indian Wells, dużo o piłce nożnej w Australii i w Polsce a na koniec o polskiej sztafecie pań w łyżwiarstwie szybkim, która wywalczyła drugi w historii medal dla Polski w zawodach rangi światowej...

We talk about the Indian Wells semifinal losses for Iga Świątek and Carlos Alcaraz, who were the defending champions at this event and considered the overwhelming favorites to defend their titles.Follow us on YouTube or Apple Podcasts as well. Download the TennisONE APP for scores, stats, news, videos, player content, fan contests, and more (https://t1.app.link/Vansh)

In this episode, we detail the role of immunoglobulins in gut-immune function, examining their involvement in mucosal defense, microbial regulation, and immune homeostasis within the intestines. We discuss the mechanisms of antibody production, highlighting how secretory IgA (sIgA) contributes to intestinal barrier integrity and pathogen neutralization. We also detail low secretory immunoglobulin A levels and Candida overgrowth. Lastly, we go through tools to support the gut-immune axis including oral immunoglobulin supplementation.1. Introduction   - Overview of immunoglobulins, roles in gut-immune health     - The gut as a constant interface with antigens, microbes, and potential pathogens     - Adequate but balanced immunoglobulin levels; preventing opportunistic pathogen overgrowth   2. Immunoglobulins     - Immunoglobulins (Ig) as glycoproteins, fundamental role in immune defense     - Five major immunoglobulin isotypes and their distinct roles     - How immunoglobulins recognize and neutralize pathogens / toxins / foreign antigens   3. Antibody Production in the Intestines    - Naïve B cells originate in the bone marrow, migrate to secondary lymphoid tissues     - Antigen-presenting cells (APCs) facilitate antigen processing and B cell activation     - Plasma cells and mucosal immunity   4. The Intestinal Barrier and Immune Components   - Layers of the gut barrier and their functions     - The role of gut-associated lymphoid tissue (GALT) in immune surveillance     - Immune cells within the lamina propria and their contributions to gut homeostasis   5. Secretory IgA (sIgA) and Its Role in Gut Immunity    - sIgA production and transport across the intestinal epithelium    - Role of sIgA in immune exclusion and pathogen neutralization  6. Factors That Can Influence sIgA Levels    - Chronic stress, infections, and gut inflammation as contributors to low sIgA     - Consequences of low sIgA, including increased susceptibility to pathogens     - Nutrients essential for supporting optimal sIgA levels   7. Other Key Immunoglobulins in Gut Immunity   - Immunoglobulin G's role in immune responses / pathogen neutralization    - Immunoglobulin M's location and function as an early immune responder in mucosal defense   8. Supplemental Immunoglobulins   - Oral immunoglobulin supplementation and its benefits    - Bovine colostrum as a source of immunoglobulins for intestinal and immune support   9. Conclusion     - Recap of immunoglobulins' role in gut-immune function    - The importance of balanced IgA, IgG, and IgM levels     - Strategies to support gut immunityThank you to our episode sponsor:1. Shop ⁠⁠CYLN's⁠⁠ full skincare line ⁠⁠here⁠⁠.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

W najnowszym odcinku Sport in Brief:- Sukcesy Polski w Halowych Mistrzostwach Europy- Afera kombinezonowa w skokach narciarskich- Iga Świątek walczy o trzeci tytuł w Indian WellsUwielbiasz podcasty? Słuchać, tworzyć, produkować, wszystko naraz? Zapisz się na newsletter Voice House o świecie podcastingu ► https://bit.ly/newsletterVoiceHouseMasz pomysł na temat? Napisz ► office@voicehouse.co 

Czy dzisiaj jest czwartek? Chyba tak, bo mamy dla Was nowy odcinek! I to jaki odcinek, kochani! Najpewniej najlepszy, jaki nam wyszedł w tym tygodniu! MAMY W NIM TEMATY! MAMY TEŻ GRANKO WIELKIE! Tomasz grał w Sunless Skies!Dominik grał w The Roottrees are Dead!Iga grała w UFO 50 i MiSide! Dziękujemy wszystkim za wsparcie na […]

Welcome to Day Three of Indian Wells! Join our hosts Steve Weissman, Coco Vandeweghe & Prakash Amiritraj as the seeds are finally hitting the court as we dive into the second round of this prestigious tournament. Today, we'll be previewing some exciting matchups, including Alexander Zverev, Iga Świątek in their respective matches and discussing whether Marcus Giron can pull off an upset against Casper Ruud. We'll also take a deep dive into the fascinating coaching dynamic between Novak Djokovic and Andy Murray. Plus, Danielle Collins has been doubling down lately, we'll discuss her five star speech on five-star vacations. To wrap things up, we're joined by tournament coordinator Tommy Haas to talk about the exciting new courts at Indian Wells, and much more! Don't miss it! Learn more about your ad choices. Visit megaphone.fm/adchoices

We react to the women's Indian Wells 2025 draw and look at the quarters of Sabalenka, Gauff, Pegula and Swiatek. Rybakina on Iga's side of the draw and can Mirra Andreeva make a run here? ❤️ SUBSCRIBE TO GTL: https://bit.ly/35JyOhz ▶️ JOIN YOUTUBE MEMBERSHIP: https://bit.ly/3Fk9rSr

JAZDA JAZDA Z TEMATEM, BO CZASU MAŁO Dziś mamy dla Was taki oto podcast – Niezatapialni. Odcinek 566. Rozmawiamy w nim o zamknięciu studia Monolith Productions, które jest (OMG) zupełnie innym studiem niż Monolith Soft. Mówimy również o planach dotyczących ekranizacji Elden Ringa. W sekcji Co Jest Grane Tomek i Iga mówią o Nosferatu, Iga […]

“When we think about sustainable living, it's not just about electricity. Energy encompasses more than electricity. As we advocate for sustainability and net zero, let's not forget the heating and cooling of our homes, businesses, and industries - geothermal is a direct resource for that.” Dr. Marit Brommer on Electric Ladies Podcast Drilling for geothermal energy - the heat beneath our feet - promises to be one of the most sustainable sources of energy and a game changer for the clean energy transition. One of the biggest opportunities lies right here in the U.S., where we have the largest installed capacity for geothermal electricity generation. Reflecting the tremendous potential of this energy source, $31 million in funding was announced for geothermal energy projects in late-2024, subject to evolving federal funding guidelines.  Listen to Dr. Marit Brommer, CEO of the International Geothermal Association (IGA) and a geologist and expert in geothermal energy. Prior to joining the IGA, she was an exploration and production technologist at Shell and Total Energy.   You'll hear about: What geothermal energy is, its applications, and its potential to be a significant player in the transition to a net-zero emissions economy.  Role of the International Geothermal Association in guiding the proper management of geothermal energy projects.  Effective policies to support geothermal development are essential to overcome the initial financial and technical risks.  Why the connection between geothermal energy and lithium production is an interesting proposition for the sector.  Plus, career advice about claiming your space.  "Get your voice heard, claim your seat at that table and understand that you don't take no for an answer. No man has ever asked me how to land his next job, get to the next career point, or do something professionally - but women do.   “The point is, we women are ultimately raised to be nice. There's nothing wrong with being nice, but in your professional life, it's equally important to stand up, know your worth, not shy away from that, claim your seat, prepare, and network.” Dr. Marit Brommer on Electric Ladies Podcast Read Joan's Forbes piece on New IRA Funding Available For Geothermal Energy - Learning From Iceland and more articles here.  You'll also like:  Jennifer Granholm, 16th U.S. Secretary of Energy, on how the clean energy transition is driving record-breaking economic growth across the country. Gauri Singh, International Renewable Energy Agency, on the deployment of clean energy around the world. Julia Souder, Long Duration Energy Storage Council, on long sharing storage for renewable energy. Gina McCarthy, Former White House National Climate Advisor & Climate Policy Head, on why climate and energy policy are huge economic drivers. Inna Braverman, Founder/CEO of Eco Wave Power, on how wave power works and her powerful personal story that reflects today's geopolitical dynamics.  Power up with the following offers!   Join us at The Earth Day Women's Summit on April 22, 2025, in Dallas, Texas! Register today with the code “EDWS” for a special rate.   Elevate your career with expert coaching and ESG advisory with Electric Ladies Podcast. Unlock new opportunities, gain confidence, and achieve your career goals with the right guidance.  Want to hear more from us?  Subscribe to our newsletter to receive our podcasts, blog, events and special coaching offers.  Thanks for subscribing on Apple Podcasts or iHeartRadio and leaving us a review!  Follow us on Twitter @joanmichelson 

It was a duet of quarterfinal losses for Iga Świątek and Carlos Alcaraz last week. Will Mirra Andreeva simply be a problem for everybody from now on? What happened to Alcaraz in the Lehecka defeat?Follow us on YouTube or Apple Podcasts as well. Download the TennisONE APP for scores, stats, news, videos, player content, fan contests, and more (https://t1.app.link/Vansh)

IgA nephropathy is a rare autoimmune kidney disease that can lead to the loss of kidney function. Though a number of treatment options exist today, none address the root cause of the disease and instead seek to manage symptoms, slow progression, or prevent complications. Vera Therapeutics' experimental fusion protein atacicept, in a phase 2B study, showed the ability to provide long-term kidney function stabilization. We spoke to Marshall Fordyce, founder and CEO of Vera Therapeutics, about IgA nephropathy, atacicept, and its potential in other B cell-mediated diseases.

W dzisiejszym magazynie sportowym: Iga Świątek odpadła w półfinale turnieju w Katarze, pechowy remis Sydney fc po utracie bramki w 95 minucie meczu, polscy księża zdobyli mistrzostwo Europy w piłce nożnej oraz Polska mistrzem świata w halowym turnieju hokeja na trawie kobiet ...

Episode 184: Multiple Myeloma BasicsSub-Interns and future Drs. Di Tran and Jessica Avila explain the symptoms, work up and treatment of multiple myeloma. Written by Di Tran, MSIV, Ross University School of Medicine; Xiyuan Yang, MSIV, American University of the Caribbean. Comments by Jessica Avila, MSIV, American University of the Caribbean. Edits by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Di: Hi everyone, this is Di Tran, 4th year medical student from Ross university.  It's a pleasure to be back.  To be honest, this project is a part of teamwork of two medical students, myself and another 4th year, her name is XiYuan.  She came from the AUC. Unfortunately, due to personal matters she was unable to make it to the recording today which makes me feel really sad. Jessica: My name is Jessica Avila, MSIV, American University of the Caribbean.Di: The topic we will present today is Multiple Myeloma. Multiple myeloma is typically a rare disease and it's actually a type of blood cancer that affects plasma cells in the bone marrow.Jessica: Let's start with a case: A 66-year-old male comes to his family doctor for an annual health checkup. He is not in any acute distress but he reports that he has been feeling tired and weaker than usual for the last 3 months. He also noticed that he tends to bruise easily. He has a history of arthritis and chronic joint pain, but he thinks his back pain has gotten worse in the last couple of months. Upon checking his lab values, his family doctor found that he has a calcium level of 10.8 and a creatinine level of 1.2, which has increased from his baseline. Given all that information, what do you think his family doctor is suspecting? And what kind of tests she can order for further evaluation?Di: Those symptoms sound awfully familiar – are we talking about the CRAB? You know, the diagnostic criteria for Multiple Myeloma.Jessica: Exactly! Those are called “myeloma-defining events.” Do you remember what those are?Di: CRAB criteria comes in 4 flavors.  It's HYPERCALCEMIA with >1mg/dL, RENAL INSUFFICIENCY with serum creatinine >2mg/dL, ANEMIA with hemoglobin value 10% plasma cells, PLUS any one or more of the CRAB features, we can make the official diagnosis of multiple myeloma. Di:  Before we go deeper, let's back up a little bit and do a little background.  So, what do we know about the immunoglobulins, also known as antibodies? Back from years of studying from medical school, we know that the plasma cells are the ones that producing the antibodies that help fight infections.  There  are various kinds that come with various functions.  Each antibody is made up of 2 heavy chains and 2 light chains.  For heavy chains, we have A, D, E, G, M and for light chains we have Kappa and Lambda.Jessica: Usually, the 5 possible types of immunoglobulins for heavy chains would be written as IgG, IgA, IgD, IgE, and IgM.  And the most common type in the bloodstream is nonetheless the IgG. Di: What is multiple myeloma? In myeloma, all the abnormal plasma cells make the same type of antibody, the monoclonal antibody.  The cause of myeloma is unknown, but there are lots of studies and evidence that show a number of potential etiologies, including viral, genetic, and exposure to toxic chemicals, especially the Agent Orange, which is a chemical used as herbicide and defoliant. It was used as a chemical warfare by the U.S. military during the Vietnam War from 1961 to 1971.Jessica: We need to order some specific blood tests to see if there is elevated monoclonal proteins in the blood or urine. So, to begin with we'll need to take a very thorough history and physical exam. Next, we'll do labs, such as CBC, basic metabolic panel, calcium, serum beta-2 microglobulin, LDH, total protein, and some not so common tests: serum protein electrophoresis (SPEP), immunofixation of blood or urine (IFE), quantitative immunoglobulins (QIg), serum free light chain assay, and serum heavy/light chain ratio assay.If any of the results is abnormal, we should consider referring our patient to an oncologist.Di: Interesting! I read that Multiple Myeloma symptoms vary in different patients.  In fact, about 10-20% of patients with newly diagnosed myeloma do not have any symptoms at all.   Otherwise, classic symptomatic presentations are weakness, fatigue, increased bruising under the skin, reduced urine output, weakened bones that is likely prone to fractures, etc. And if multiple myeloma is highly suspected, a Bone Marrow biopsy should be done with testing for flow cytometry and fluorescent in situ hybridization (FISH). Actually, if any of the “Biomarkers of malignancy (SLIM)” is met we can also diagnose multiple myeloma even without the CRAB criteria. Jessica: The diagnosis is made if one or more of the following is found: >= 60% of clonal plasma cells on bone marrow biopsy, > 1 lytic bone lesion on MRI that is at least 5mm in size, or a biopsy confirmed plasmacytoma. Di: Imaging comes in at the final step especially if we able to find one or more sites of osteolytic bone destruction > 5mm on an MRI scan.Jessica: What if the bone marrow biopsy returns > 10% of monoclonal plasma cells, but our patient doesn't have either the CRAB or the Biomarker criteria? Di: That's actually a very good question, since Multiple Myeloma is part of a spectrum of plasma cell disorders. That's when smoldering myeloma comes into play. It is a precursor of active multiple myeloma. Smoldering myeloma is further categorized as high-risk or low-risk based on specific criteria.A less severe form is called Monoclonal Gammopathy of Undetermined Significance, or simply MGUS, with < 10% bone marrow involvement. Those are diagnoses we give once we rule out actual multiple myeloma, which are defined by the amount of M-protein in the serum.Jessica:  When to get started on treatment? Multiple Myeloma is on a spectrum of plasma cells proliferative disorders, starting from MGUS to Smoldering Myeloma, to Multiple Myeloma and to  Plasma Cell Leukemia.  Close supervision/active watching is enough for MGUS and low risk Smoldering Myeloma. But once it has progressed to high-risk smoldering myeloma or to active Multiple Myeloma, chemotherapy is usually required. Some situations may require emergent treatment to improve renal function, reduce hypercalcemia, and to prevent potential infections.Di: As of 2024, treatment of Multiple Myeloma comprises the Standard-of-Care approved by the FDA. In fact, the quadruple therapy is a combination of 4 different class of drugs that include a monoclonal antibody, a proteasome inhibitor, an immunomodulatory drug, and a steroid. Jessica: They are Darzalex (daratumumab), Velcade (bortezomib), Revlimid (lenalidomide) and dexamethasone.  Other treatment plans for Multiple Myeloma include chemotherapy, immunotherapy, radiation therapy (for plasmacytomas) and stem cell transplants. The patient will also be on prophylaxis acyclovir and Bactrim while on chemotherapy. Sometimes anticoagulants are also considered because the chemo increases the risk of venous thromboembolic events.Di: Although the disease is incurable, but with the advancing of novel therapies and clinical trials patients with multiple myeloma are able to live longer.  Problem is the majority of patients diagnosed with Multiple Myeloma are older adults (>65), the risk of falling is adding to multiple complications of the disease itself, such as bone density loss, pain, neurological compromises, distress and weakness.  Palliative care may come in help at any point in time throughout the course of treatment but is most often needed at the very end of the course. Jessica, can you give us a conclusion for this episode?Jessica: Multiple Myeloma may not be the most common cancer, but we have to be aware of the symptoms and keep it in our differential diagnosis for patients with bone pain, easy bruising, persistent severe headaches, unexplained renal dysfunction, and remember the CRAB: HyperCalcemia, Renal impairment, Anemia and Bone lesions.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:International Myeloma Foundation. (n.d.). International Myeloma Working Group (IMWG) criteria for the diagnosis of multiple myeloma. https://www.myeloma.org/international-myeloma-working-group-imwg-criteria-diagnosis-multiple-myeloma Laubach, J. P. (2024, August 28). Patient education: Multiple myeloma symptoms, diagnosis, and staging (Beyond the Basics). UpToDate. https://www.uptodate.com/contents/multiple-myeloma-symptoms-diagnosis-and-staging-beyond-the-basics.University of California San Francisco. (n.d.). About multiple myeloma. UCSF Helen Diller Family Comprehensive Cancer Center. https://cancer.ucsf.edu/research/multiple-myeloma/about Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

Today on TC Live, our attention is stretched across 4 separate continents and midway as we check out the biggest moments midway through these tournaments. In Delray, the former ranked No. 8 Diego Schwartzman is keeping the dream alive as he battles for his final ATP title in the last tournament of his career. Speaking of keeping the dream alive, Iga Świątek digs deep and comes back after losing the first set in her match against Linda Nosková and keeps the four-peat dreams alive in Doha. All these stories for you and a whole lot more on TC Live. Learn more about your ad choices. Visit megaphone.fm/adchoices

Today on TC Live, our attention is split between four jam-packed tournaments: Doha, Marseille, Buenos Aires, and Delray Beach. In Doha, Iga Świątek is on her way to taking the crown for the fourth year straight in Qatar. Denis Shapovalov also stops by for a quick chat after his win in Dallas. Plus, Serena Williams makes a guest appearance at the Super Bowl Halftime Show. Hear about all this and more with our hosts Steve Weissman, Prakash Amritage, and Paul Annacone on TC Live Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, we discuss the relationship between the intestinal mucus layer and secretory immunoglobulin A (sIgA), highlighting both as key components of the gut's first line of defense against pathogens, toxins, and environmental stressors. We detail how dysbiosis and microbial overgrowths can impact sIgA levels and can disrupt mucus integrity and function, contributing to increased intestinal permeability and inflammation. We then examine several additional factors influencing sIgA production. Topics: 1. Introduction: Importance of Secretory IgA and Intestinal Mucus     - Intestinal epithelial lining and its protective mucus layer     - Focus on intestinal dysbiosis and sIgA   2. Anatomy of the Gastrointestinal Lining     - Intestinal lumen, microbiome, mucus layer, epithelial cells, tight junctions, lamina propria, and smooth muscle     - Role of goblet cells in mucus secretion and epithelial integrity    3. Role of the Protective Mucus Layer     - Dual function of the mucus layer as a physical and biochemical barrier     - Composition of mucus: mucins, antimicrobial peptides, immunoglobulins    4. Goblet Cells and Mucin Production     - Mechanisms of mucin secretion and hydration     - Variability in goblet cell density across the intestinal tract     - Dysfunctions linked to conditions like IBD and IBS    5. Microbial Interactions with Mucins     - Glycan structures in mucins    - Roles of commensal and pathogenic bacteria in mucin degradation and mucus turnover     - Importance of regulated mucus production for gut homeostasis    6. Dysbiosis and Mucus Degradation     - Excessive mucin degradation leading to thinning of the mucus layer     - Consequences of increased intestinal permeability and inflammation     - Role of dysbiosis in disrupting the mucus layer    7. Overview of Secretory IgA     - Introduction to secretory IgA (sIgA) and its role in mucosal immunity    - Mechanisms of immune exclusion and pathogen neutralization    8. Production and Function of Secretory IgA     - sIgA production by plasma cells in the lamina propria     - Translocation of IgA through epithelial cells into the gut lumen     - sIgA binding to mucins and its immunological role in the mucus layer    9. Factors Affecting Secretory IgA Levels     - Possible contributing factors to low sIgA levels    - Implications of low and high sIgA levels for immune defense and intestinal health    10. Interactions Between Secretory IgA and Dysbiosis     - Cyclical relationship between low sIgA, dysbiosis, and infections     - Examples of overgrowths, like candida, disrupting sIgA     - Importance of addressing immune dysregulation to break the cycle    11. Bioindividual Root Cause Approach  - Factors to consider Thank you to our episode sponsors: 1. Shop ⁠⁠Fresh Press Farms⁠⁠' Peach Cider Vinegar at Sprouts locations nationwide, and check out their full collection ⁠⁠here⁠⁠. 2. Check out ⁠Spectrum Sciences⁠' Serums and The Vitamin B12 Protocol ⁠here⁠, and use code CHLOE15 for 15% off. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Woolworths? Coles? IGA? Aldi? NO THANKS. At Filthy Casuals, we choose to do all of our grocery shopping at the Costa Rican Super Mario supermarket chain, which this week has had a landmark victory against the famously litigious Big N. We also chat about Dragon Age: The Veilguard not living up to certain expectations, the pressures on smaller studios to pull the pin on projects that aren't shaping up how they want, plus we review Citizen Sleeper 2: Starward Vector, Super Kiwi 64, Cavern Of Dreams and The Roottrees Are Dead! Get an exclusive 15% discount on Saily data plans! Use code FILTHY at checkout. Download the Saily app or go to https://saily.com/filthy Hosted on Acast. See acast.com/privacy for more information.

Featuring articles on IgA nephropathy, a treatment in children with obesity, NRG1 fusion–positive cancer, a case of a T-cell lymphoma, and the discovery of GLP-1–based drugs; a review article on hemophagocytic lymphohistiocytosis, a Clinical Problem-Solving on traveling companions; and Perspectives on cell and gene therapies, on gender-affirming care, and on the man who lives in the cardboard box.

Feel like in a sea of people you're never the immediate choice? This is something you want to program into your electromagnetic field if you want to be the one that shines above the rest in your career, love life, friendships, and all relationships!-We discuss how to do this, among other topics such as LOUD recent reflections and why you might be advancing through challenges currently as well.-If you're not feeling LFG!!! energy in the new year and why that's actually completely natural.-DM me your Apple review and I'll send you back a free gift!RESOURCES:Manifest From Power The MembershipInvite-Only 3-Day Free TrialIT GIRL PREP while you wait for IGA to re-open

In this episode of the Identity at the Center podcast, hosts Jeff and Jim discuss the vital role of user access reviews, device identity, and the evolving landscape of Identity Access Management (IAM) with guest Stephen Washington, Head of IAM at Discover Financial. The conversation delves into regulatory compliance, the use of AI in IAM, and practical steps for improving user access certifications. They also explore the importance of managing service accounts, innovations in IGA, and the role of identity in modern cybersecurity frameworks. The episode wraps up on a lighter note with a chat about fitness challenges like Tough Mudder and personal cheese preferences for grilled cheese sandwiches. Chapters 00:00 Introduction to Regulatory Compliance in Financial Services 01:54 Welcome to the Identity at the Center Podcast 02:07 Exploring Device Identity 03:19 The Role of Identity in Modern Security 06:44 Engaging with the IAM Community 10:31 Upcoming Conferences and Events 13:58 Interview with Stephen Washington 25:36 The Importance of User Access Reviews 33:55 Backend Changes in IGA Systems 35:04 The Concept of Identity Data Lake 36:37 AI and Identity Fatigue 37:22 Importance of Identity Hygiene 38:32 Challenges with Access Reviews 39:42 Regulatory Compliance and Policy Changes 41:06 Advice for Practitioners on Access Reviews 45:47 NYDFS and User Access Reviews 47:41 The Role of NIST Cybersecurity Framework 52:35 Training Auditors and Policy-Based Access Control 57:38 Fitness and Stress Relief 01:05:38 Grilled Cheese and Final Thoughts Connect with Stephen: https://www.linkedin.com/in/stephen-washington-jr-5569b57/ Gartner IAM Summit - Code IDAC425 saves 425€: https://www.gartner.com/en/conferences/emea/identity-access-management-uk European Identity and Cloud Conference 2025 - Use code idac25mko for 25% off: https://www.kuppingercole.com/events/eic2025?ref=partneridac Identiverse 2025 - Use code IDV25-IDAC25 for 25% off: https://identiverse.com/ Connect with us on LinkedIn: Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/ Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/ Visit the show on the web at http://idacpodcast.com

Jelena Dokic on the trauma and violence which underscored her extraordinary life in tennis, and how she worked to change her own story(CW: discussion of family violence, eating disorders) (R)After arriving in Australia with her family as a refugee, Jelena Dokic became a tennis champion while still a teenager.But her father's drunken outbursts at Jelena's tournaments got even more headlines than her playing.What the world didn't know was that Jelena's father was also violently assaulting her and had been since the day she first picked up a tennis racquet.Jelena finally found the courage to tell the truth about what happened to her, but she discovered that was only the first step in escaping her father.This episode of Conversations explores family dynamics, origin story, body shaming, dysfunctional families, abuse allegations, childhood abuse, child athletes, elite athletes, the Australian Open, Tennis, Novak Djokovic, Alexander Zverev, Shelton, Alex de Minaur, Madison Keys, Iga Świątek, Aryna Sabalenka.

This episode is sponsored by Andromeda Security. Learn more at https://www.andromedasecurity.com/idac⁠ Join Jeff and Jim on the Identity at the Center podcast as they chat with Ashish Shah, co-founder and Chief Product Officer of Andromeda Security. In this sponsored episode, Ashish dives deep into the importance of solving identity security problems, especially in cloud and SaaS environments. He explains how Andromeda's AI-powered platform focuses on both human and non-human identities, offering use case-driven solutions for security maturity. The discussion covers challenges, AI and machine learning applications, and practical insights into permissions management, risk scoring, just-in-time access, and more. Stay tuned for interesting takes on identity security and some fun recommendations for your reading/listening list. Chapters 00:00 Introduction to Identity as a Data Problem 00:41 Overview of Andromeda's Capabilities 01:27 Welcome to the Identity at the Center Podcast 02:03 Meet Ashish Shah, Co-Founder of Andromeda 02:37 The Genesis of Andromeda 03:33 Addressing Identity Security Challenges 05:29 Andromeda's Approach to Identity Security 09:44 Measuring Success with Andromeda 12:21 Andromeda's Market Position and Ideal Customers 18:35 The Rise of Non-Human Identities 28:42 Understanding Identity and Accounts in AWS 28:54 The Concept of Incarnations in Identity Management 29:42 Human and Non-Human Identities 32:13 Challenges in Authorization and Access Control 32:44 Implementing Zero Trust and Least Privilege 35:10 Role of AI and Machine Learning in Identity Management 36:21 Risk Scoring and Behavioral Analysis 39:04 Customer Data and Model Training 41:08 Explainability and Security of AI Models 46:14 Customer Influence on Model Tuning 49:03 Andromeda's Offer and Final Thoughts 51:34 Book Recommendations and Closing Remarks Connect with Ashish: https://www.linkedin.com/in/ashishbshah/ Learn more about Andromeda: https://www.andromedasecurity.com/idac⁠ Connect with us on LinkedIn: Jim McDonald: https://www.linkedin.com/in/jimmcdonaldpmp/ Jeff Steadman: https://www.linkedin.com/in/jeffsteadman/ Visit the show on the web at idacpodcast.com and watch at https://www.youtube.com/@idacpodcast Keywords: Identity security, IAM, cybersecurity, artificial intelligence, AI, machine learning, ML, non-human identities, NHI, just-in-time access, JIT, IGA, privileged access management, PAM, identity threat detection and response, ITDR, cloud security, SaaS security, Andromeda Security, Ashish Shah, IDAC, Identity at the Center, Jim McDonald, Jeff Steadman

As the Australian Open hits the business end of the tournament, Something Major is here to break down all the quarterfinal action from both the men's and women's draws.On the men's side, we kick off with Djokovic's gritty win over Alcaraz before moving onto Shelton's big-match energy, Zverev's chances for a title and Jannik Sinner's dominant performance over De Minaur. Is Sinner the favorite to win it all now? And can Zverev get his first Grand Slam win over Djokovic?On the women's side, we spotlight Sabalenka's hard court dominance, Badosa's surprising win over Coco, and Swiatek's machine-like approach as she marches through the draw. Who is the current favorite? And can Madison Keys pull off the upset of the tournament with a semifinal showdown against Iga?Last but not least, we close the show with a Snake Draft update (pickleball showdown pending!) and Aussie Open trivia.(00:00) On today's episode…(00:47) The wet handshake reaction & what's ahead(02:06) Djokovic's gritty win over Alcaraz(07:12) Did Paul let his match vs. Zverev slip away?(11:12) Can Zverev actually win?(12:52) Shoutout: Moutet is Sam's new favorite artist(13:35) Shelton's Slam-winning it-factor(15:56) Sinner's surreal moment(18:18) Why Shelton isn't afraid of Sinner(20:32) Badosa's big upset over Gauff(23:02) Sabalenka's rise: Australia's new Queen?(24:20) The friendship factor in high-stakes matches(25:17) “Iga is a machine!”(27:32) Tech controversies: Old-school vs. VAR(30:34) Can Keys give Swiatek trouble?(33:31) Semifinals predictions(36:30) Snakedraft update & punishments!(38:10) Fan shoutouts(38:58) Goodbye & AusOpen trivia! Hosted on Acast. See acast.com/privacy for more information.

Our CTC LIVE series is back for the Australian Open, rounding up all the action from Dan's first-hand experience in Melbourne!In this episode, Dan discusses the latest matches, such as Zverev v Tommy Paul, Baddosa reaching her 1st Grand Slam semi-final as well as both doubles teams of Gaby Dabrowski and Erin Routliffe and Michael Venus and Erin Routliffe both reach doubles semi-finals!Dan shares insights on surprising tournament outcomes, the emergence of young talents, predictions for the doubles events and answers questions from our listeners!Also talking about Iga Świątek being unfazed by her drug ban and dominating her opponents, dropping only 11 games total on the way to the AO quarter-final.This is the place to get a quick summary of the events at the Australian Open from a coach's perspective.These shorter episodes aim to provide a round-up of the Australian Open action in Melbourne with Dan Kiernan, coach of doubles pairs Gaby Dabrowski and Erin Routliffe and Michael Venus and Nikola Mektić!Make sure to check out the Australian Open PREVIEW FULL EPISODE out on all podcast platforms!Chapters00:00 Welcome to the Australian Open Round Up05:56 Surprises and Highlights of the Tournament11:51 Young Talents and Future Stars17:35 Iga's Journey and Being Unfazed by the Controversy YouTube: Control the Controllables PodcastInstagram: ctc.podcastTwitter (X): ctc_podcastTikTok: Control the Controllables Podcast Thank you everyone for listening!

Jannik Sinner is currently defending his title as the world’s best male tennis player at the Australian Open. But come April, he’ll be defending himself in another arena – the Court of Arbitration for Sport. Last year, the tennis world was shocked by revelations both Sinner and women’s world No. 2 Iga Świątek had tested positive for banned substances. Their cases were resolved in private, raising concerns their high profiles and considerable resources gave them an unfair advantage when it came to dodging public scrutiny. Today, sports journalist and author of the Substack “But Do You Actually Like Sport?”, Molly McElwee, on the twin doping scandals overshadowing the Australian Open. Socials: Stay in touch with us on Twitter and Instagram Guest: Sports journalist Molly McElweeSee omnystudio.com/listener for privacy information.

And just like that, the 2025 Australian Open is nearly underway. It's the 40th major we've covered as a podcast, and our draw previews are still as prediction-free as always. We touch on a few of the themes to watch out for in Melbourne – Sinner's emotional state, Rybakina's coaching situation, Novak as #7 seed and poisonee – but mostly this is a lighthearted preview with draw breakdowns and our most intriguing first rounds.  GoFundMe: help fund our 2025 season! 3:15 Stories to follow: heavy metals, jumping ants 13:50 Comebacks and withdrawals 18:50 Women's draw analysis: a tough one for Coco 27:40 Women's bottom half: will Iga reverse her luck in Australia? 38:05 Men's draw analysis: the top tier and the middlemen 54:50 Men's bottom half: Djokovic as a #7 seed sounds wrong

On Monday Match Analysis, Gill Gross shouts out Jiri Lehecka and Alexandre Muller for their title runs before delving into Reilly Opelka's splashy win over Novak Djokovic on his title run in Brisbane, Coco Gauff's second straight win over troublesome rival Iga Swiatek and Taylor Fritz's high-quality victory over Hubert Hurkacz to secure the United States its second United Cup title in three years. 00:00 Intro 01:00 Muller & Lehecka 03:15 Opelka Deep Dive 10:26 Djokovic Match 27:50 Gauff d. Swiatek 38:50 Iga's MTO 44:25 Fritz d. Hurkacz 56:00 United Cup IG: https://www.instagram.com/gillgross_/ 24/7 Tennis Community on Discord: https://discord.gg/wW3WPqFTFJ Twitter/X: https://twitter.com/Gill_Gross The Draw newsletter, your one-stop-shop for the best tennis content on the internet every week: https://www.thedraw.tennis/subscribe

Will 2024 be Iga's year of purging demons so 2025 can come back stronger? What was with Paula Badosa's strange US Open ender? Yes, Rennae and Petko finally discuss some of the men and what they might get up to next year (including Rybakina's new coach, Goran)! See omnystudio.com/listener for privacy information.