Podcasts about Fat

Esters of three fatty acid chains and the alcohol glycerol, one of the three main macronutrients, also known as triglycerides

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    Apple News Today
    Samin Nosrat doesn't love Thanksgiving food. Here's what she says will improve it.

    Apple News Today

    Play Episode Listen Later Nov 22, 2025 29:38


    From Apple News In Conversation: With the release of her James Beard Award–winning cookbook, Salt, Fat, Acid, Heat, Samin Nosrat catapulted to international fame. But amid big life changes and loss in the years that followed, she struggled to redefine her connection to cooking. With her second book, Good Things, Nosrat is back with a fresh approach to preparing food — one that’s centered on spending precious time with loved ones. She sat down with Apple News In Conversation host Shumita Basu to talk about what makes a good recipe, her weekly dinner-party group, and how to alleviate the stress of cooking a high-stakes holiday meal.

    The Human Upgrade with Dave Asprey
    10-Minute Biohacking News Update : 1367

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 21, 2025 9:45


    This episode covers: • Nano CBD Pain Relief Without Cognitive Side Effects A new nano-micelle formulation of CBD called CBD-IN delivers fast, non-addictive pain relief in mice without memory issues, motor impairment or the usual cannabinoid “fog.” Because it crosses the blood brain barrier and directly targets hyperactive pain circuits, it sidesteps many opioid-type drawbacks. Dave explains why precision-designed cannabinoids could reshape chronic pain treatment and longevity support. Source: https://www.sciencedaily.com/releases/2025/11/251117095652.htm • Moderate Calorie Restriction Slows Biological Aging A long-term trial from the National Institute on Aging found that cutting calories by about 12% over two years slowed the pace of aging — measured by methylation clocks and metabolic markers — in lean and mildly overweight adults alike. Dave breaks down why small, manageable dietary tweaks can deliver big longevity gains, without crash dieting or extreme fasting. Source: https://www.nia.nih.gov/news/cutting-calories-may-slow-pace-aging-healthy-adults • FDA Approves AI-Guided Robotic Surgery Trials for Alzheimer's The U.S. Food and Drug Administration (FDA) has granted IDE approval for the first robotic microsurgical study targeting early stage Alzheimer's disease using AI and deep imaging. The trial uses adaptive robotics to target deep brain lymphatic pathways, potentially clearing amyloid/tau deposits with surgical precision. Dave explains why this signals a new era in neurodegeneration – moving from drug-only to machine-assisted brain repair. Source: https://www.mmimicro.com/ide-approval-for-first-robotic-microsurgery-alzheimers-study/ • Antibiotic Reprograms Gut Bacteria to Produce Anti-Aging Molecules Researchers demonstrated that the veterinary antibiotic cephaloridine can reprogram gut microbes to secrete colanic acid — a molecule linked to better mitochondrial health, reduced gut permeability and improved cholesterol/insulin balance in mice. Dave explores how this could evolve into a pipeline of engineered probiotics that act as internal “longevity factories.” Source: https://newatlas.com/aging/antibiotic-longevity-microbiome/ (link remains unchanged) • Klotho: The Longevity Protein Nears Clinical Reality The longevity protein Klotho, known for clearing toxic by-products, calming inflammation and protecting brain/organ networks, is now advancing toward human trials via injectables, oral formats and gene therapy. Dave explains why Klotho is shaping up as a foundational target for next-gen age-reversal strategies and stacking protocols. Source: https://investingnews.com/longevity-focused-health-fueling-u-s-anti-aging-products-market-projected-to-reach-27-billion-by-2033/ (link remains unchanged) All source links provided for easy reference to the original reporting and research above. This episode is essential listening for fans of biohacking, human performance, functional medicine and longevity who want practical tools from Host ­Dave Asprey and the latest breakthroughs shaping the future of health. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade gives you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio only) and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: nano CBD, CBD-IN, pain relief research, non opioid pain therapies, chronic pain and aging, caloric restriction aging, methylation clocks, metabolic resilience, AI robotics, Alzheimer's microsurgery, neurotech advancement, microbiome engineering, colanic acid, longevity probiotics, mitochondrial support, Klotho protein, anti aging gene therapy, cellular rejuvenation, longevity news, biohacking updates Thank you to our sponsors! LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Intro 0:19 — Story 1: Nano CBD for Pain Relief 1:53 — Story 2: Caloric Restriction and Aging 3:20 — Story 3: AI Robotic Surgery for Alzheimer's 4:50 — Story 4: Microbiome Reprogramming 6:05 — Substack Announcement 7:04 — Story 5: Klotho Longevity Protein 8:39 — Weekly Homework 9:31 — Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Science Vs
    Never Put Meatballs on Spaghetti, with Samin Nosrat

    Science Vs

    Play Episode Listen Later Nov 20, 2025 55:49


    Every day we're all doing a little bit of chemistry: when we bake potatoes, add a little salt to our pasta, or even bake a box cake. And award-winning chef Samin Nosrat just loves to nerd out over all this. She's the author of the best-selling book “Salt, Fat, Acid, Heat” and has a new book out called “Good Things.” Today, Samin joins us to talk all about the science and art of cooking. Plus — why you should NEVER put meatballs on spaghetti. Video available on Spotify. Find our transcript here: https://bit.ly/ScienceVsSaminNosrat  Samin's Book: https://ciaosamin.com/shop/good-things  In this episode, we cover: (00:00) Welcome to Science Chats with Samin Nosrat (01:27) Samin's childhood in California (06:05) Samin's obsession with boxed cake mix (14:29) Why salt, fat, acid and heat matter (17:17) The magic of salt (21:11) Why soy sauce and cheese can bring out big feelings (32:26) Why we bake with room-temperature eggs (34:32) Why tomatoes don't belong in the fridge (37:00) The geopolitics of cinnamon (40:07) Why vanilla beans cost so much (42:15) The value of handmade food (47:10) Why you shouldn't put meatballs on spaghetti This episode was produced by Wendy Zukerman, with help from Meryl Horn, Ekedi Fausther-Keeys, Michelle Dang, and Rose Rimler. We're edited by Blythe Terrell. Video editing and sound design by Bobby Lord. Fact checking by Diane Kelly. Music written by Emma Munger, So Wylie, Peter Leonard, Bumi Hidaka and Bobby Lord. Thanks to Roland Campos, Skyline Studios and Humdinger Studios. Science Vs is a Spotify Studios Original. Listen for free on Spotify or wherever you get your podcasts. Follow us and tap the bell for episode notifications.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

    The Human Upgrade with Dave Asprey
    The Methylene Blue Episode | Solo Biohacking Masterclass : 1366

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 20, 2025 35:37


    Methylene blue is one of the most misunderstood compounds in biohacking, yet it can upgrade your energy, mood, memory, and cellular resilience when you use it the right way. We are back again with another solo masterclass, and this one breaks down how to use methylene blue as a precision tool for brain optimization, longevity, and human performance while avoiding the dosing mistakes that create jitteriness, sleep disruption, or dangerous interactions. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey guides you through more than a century of research on methylene blue. He has been hacking this compound since the early 2000s and brings deep insight into mitochondria, neuroplasticity, metabolism, supplements, fasting, red light, ketosis, nootropics, and functional medicine. You will learn how methylene blue works inside the cell, how it improves electron transport, and why it appears in neurology, psychiatry, and anti aging research at the same time. This episode shows you how to test your own dose, how to stack it with light and ketosis for maximum effect, and how to avoid serotonin syndrome or sleep disruption. Methylene blue also touches nearly every major system that biohackers care about, which is why this solo masterclass shows you how it interacts with mitochondria, neuroplasticity, metabolism, sleep optimization, and long term anti aging pathways. You will hear how it influences redox balance, ATP production, brain optimization, and stress resilience, and how it behaves when combined with ketosis, fasting, creatine, NAD boosters, red light therapy, or other nootropics. Host Dave Asprey explains why methylene blue pairs well with certain supplements but clashes with psychedelics or SSRI medications, how it fits into functional medicine protocols for mitochondrial repair, and how to use data and wearable tracking to dial in your response. This episode gives you a complete framework to evaluate whether methylene blue belongs in your personal longevity strategy and how to use it with precision instead of guesswork. You'll Learn: • Why methylene blue acts like mitochondrial jumper cables and when it improves energy and mood • The exact signs that your dose is too strong, too weak, or in the Goldilocks zone • How methylene blue interacts with neuroplasticity, memory circuits, and cognitive resilience • Why psychedelics, SSRIs, and MAO inhibitors can create dangerous serotonin interactions • How to pair methylene blue with red light therapy, ketosis, creatine, fasting, or NAD boosters • The link between mitochondrial health, fertility, libido, and long term anti aging strategies • How to track sleep optimization, HRV, and performance signals to dial in your personal protocol • The difference between aquarium grade dye and pharmaceutical grade formulations • Why genetic testing for G6PD deficiency is essential before higher dose experimentation Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: methylene blue dosing, mitochondrial electron transport, Complex IV cytochrome c oxidase, redox cycling, MAO inhibition, serotonin syndrome risk, G6PD deficiency caution, neuroplasticity enhancement, dendritic spine density, mitochondrial stress adaptation, red light therapy stacking, cognitive performance optimization, ketone supported ATP production, nitric oxide independent focus boost, mitochondrial bottleneck repair, pharmaceutical grade methylene blue, sleep disruption signals, biohacking fertility support, oxidative stress buffering, functional medicine mitochondria repair Thank you to our sponsors! -BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction 4:51 — History of methylene blue 7:38 — How methylene blue works 14:05 — Safety 17:53 — Dosing and timing guidelines 20:41 — Combining with red light therapy 22:41 — Quality and sourcing 23:17 — Dosing protocols 25:24 — Longevity and fertility effects 29:24 — Stacking options 32:10 — Common questions and FAQs 33:40 — Future research and wrap up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Burnt Toast by Virginia Sole-Smith
    You Don't Have to Be a Super Ager

    Burnt Toast by Virginia Sole-Smith

    Play Episode Listen Later Nov 20, 2025


    You're listening to Burnt Toast! I'm Virginia Sole-Smith. Today, my conversation is with Debra Benfield, RDN.Deb is a registered dietitian/nutritionist with 40 years of experience helping people heal their relationship with food, movement and their bodies. Her work sits at the intersection of anti-ageism, body liberation and trauma-informed care, offering a radically compassionate alternative to diet and wellness culture—especially for those in midlife and beyond. After turning 60, Deb began questioning the dominant narratives around aging, vitality and beauty, and quickly realized the majority of resources still centered weight loss and youthful appearance as the ultimate goals. In response, she created what she couldn't find: A framework for nourishing the body that honors body respect, prioritizes liberation and embraces the full spectrum of aging. Deb is the author of the beautiful new book Unapologetic Aging: How to Mend and Nourish Your Relationship with Your Body.  Deb came on the podcast back in 2023 and we had what was really the first, or certainly one of the first, conversations we've had on Burnt Toast about the intersection of ageism and anti-fat bias. That discussion helped lay the foundation for how we're continuing to talk about those issues. Deb is someone I always turn to for resources and wisdom as we're navigating those conversations here. I am so thrilled to have Deb back on the podcast today, to talk about her new book, how diet culture has hijacked the menopause discourse, and why peanut butter and jelly sandwiches are actually giving you all the protein you need.  Unapologetic Aging comes out on December 16, so now is the perfect time to pre-order it as a holiday gift for yourself, your mom, or anyone you know in midlife and beyond! And don't forget that if you've bought Fat Talk from Split Rock Books, you can take 10% off your purchase of Unapologetic Aging there too — just use the code FATTALK at checkout.And if you value this conversation, a paid subscription is the best way to support our work!Join Burnt Toast!

    The Reach Your Peak Experience
    #301: The ONE Question EVERY “Dieter” Needs To Ask Before Starting A Fat Loss Journey

    The Reach Your Peak Experience

    Play Episode Listen Later Nov 20, 2025 7:31


    If you are planning to or already have started your weight loss/fat loss journey, there is one question you definitely should ask yourself.The answer to this question will help prepare you for what's to come, set realistic expectations, frame your strategy approach, and set you up to do better.Trust me, I'm a Dietitian and I have been in the space for many years helping clients of all walks of life. Fat loss is simple, but it is simple. And giving yourself the best chance by looking inward, is an underrated spark plug for you.In this episode, I share with you the 1 question everyone should ask themselves before starting to try and achieve weight loss. DISCLAIMER: The information in this video is for guidance only and is not individualized advice for you! Your unique situation needs to be taken into consideration and adjusting your dietary intake.____________________________________________DOWNLOAD MY FREE MACRO NUTRITION CHEATSHEET Your Guide To Improving Your Macros & Making Meal Prep Easierhttps://theclimbingdietitian.lpages.co/macro-cheatsheet-the-climbing-dietitian/Apply for Bespoke 1:1 Macro Sherpa Nutrition Coaching Program: https://bit.ly/395QmGsCheck out and SUBSCRIBE to my YouTube channel: https://bit.ly/2Mxqs4WEmail me: aleksa@theclimbingdietitian.com.auTo find me on socials:Instagram: https://www.instagram.com/theclimbingingdietitianTikTok: https://www.tiktok.com/@theclimbingdietitianFacebook: https://www.facebook.com/theclimbingdietitianTwitter: https://twitter.com/beardyAPDLink to blog: https://bit.ly/330ULq4Check out my website for more information on me and what I do:https://www.theclimbingdietitian.com.au

    The Bonfire with Big Jay Oakerson and Dan Soder
    Andy Garbage w/ H. Foley & Kevin Ryan

    The Bonfire with Big Jay Oakerson and Dan Soder

    Play Episode Listen Later Nov 19, 2025 39:22


    Modern medicine has helped Big Jay and Kevin Ryan get skinny but their fat wardrobe problems are still service memories. Foley and Bobby have to stretch out their sweaters and shirts before wearing. Perspiration is a common enemy of all these big fellows. | Jacob doesn't think he dresses like a dandy, but prefers to be called a fancy gentleman. Kevin Ryan and H. Foley's podcast is called "Are You Garbage" and they are on tour now! *To hear the full show to go www.siriusxm.com/bonfire to learn more! FOLLOW THE CREW ON SOCIAL MEDIA: @thebonfiresxm @louisjohnson @christinemevans @bigjayoakerson @robertkellylive @louwitzkee @jjbwolf Subscribe to SiriusXM Podcasts+ to listen to new episodes of The Bonfire ad-free and a whole week early.  Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    The Eric Zane Show Podcast
    EZSP 1638 - Act 1 - EZ "Clean Eating" Day 2

    The Eric Zane Show Podcast

    Play Episode Listen Later Nov 19, 2025 46:37


    ***Please help with a donation for the Great Food Giveaway #6 Venmo: @Eric-Zeitunian - CashApp: $EricZeitunian - PayPal: Search Eric Zane Show LLC******Feminine Hygiene product Wish List: https://a.co/7QY3Grs***Note: "Act 2" will be a separate published audio podcast.*Check out EZ's morning radio show "The InZane Asylum Q100 Michigan with Eric Zane" Click here*Get a FREE 7 day trial to Patreon to "try it out."*Watch the show live, daily at 8AM EST on Twitch! Please click here to follow the page.Email the show on the Shoreliners Striping inbox: eric@ericzaneshow.comTopics*EZ's "Fat awakening" has him taking each moment with trepidation.*EZ and the gang making progress with Great Food Giveaway #6 fundraising.*EZ connects with local TV station to promote GFG 6.*EZ harkens back to one year ago when he lost his mind after losing his phone at the TV station.*Big Fraud Wednesday preview.*Free Beer "Brain Tumor Talk" montage takes while EZ on potty break.'SponsorsMerchant Automotive, SkyDive Grand Haven, Impact Power Sports, Frank Fuss / My Policy Shop Insurance, Kings Room Barbershop, The Mario Flores Lakeshore Team of VanDyk Mortgage, Shoreliners Striping, Ervines Auto Repair Grand Rapids Hybrid & EV, TC PaintballInterested in advertising? Email eric@ericzaneshow.com and let me design a marketing plan for you.Contact: Shoreliners Striping inbox eric@ericzaneshow.comDiscord LinkEZSP TikTokSubscribe to my YouTube channelHire me on Cameo!Tshirts available herePlease subscribe, rate & write a review on Apple Podcastspatreon.com/ericzaneInstagram: ericzaneshowTwitterOur Sponsors:* Check out Secret Nature and use my code ZANE for a great deal: https://secretnature.com* Check out Uncommon Goods: https://uncommongoods.com/zaneSupport this podcast at — https://redcircle.com/the-eric-zane-show-podcast/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

    Learning to Glow: Tips for Women's Health, Optimal Wellness and Aging Gracefully
    149: The Hidden Emotional Patterns Driving Your Eating with Sandy Zeldes

    Learning to Glow: Tips for Women's Health, Optimal Wellness and Aging Gracefully

    Play Episode Listen Later Nov 19, 2025 45:04


    Send us a textIn today's episode, I sit down with Sandy Zeldes — a holistic health expert, intuitive guide, and self-proclaimed spiritual cowgirl — and we dive into the real roots of why so many high-achieving women struggle with food, their bodies, and the pressure to “hold it all together.”This conversation goes way beyond nutrition. Sandy brings a powerful blend of trauma healing, emotional belief work, and ancestral nutrition, and she shares why food issues are almost never about food.What We Talk AboutHow guilt, shame, and self-judgment around food show up for women The deeper emotional patterns that often form in childhood — and how they drive our eating behaviors as adultsWhy focusing only on diet keeps us stuck, and how addressing the nervous system finally creates lasting changeSandy's approach to integrating EFT tapping for emotional release and regulationWhat “ancestral nutrition” actually means and why it's so different for each personHow we sabotage ourselves (and how to stop repeating those same cycles)Find Sandy: Click Here for all of the links! As always, thank you for listening — and make sure to subscribe so you don't miss next week's episode!

    The Training Project | Fitness Podcast
    Take a Left Turn: Building Strength with UK Trainer Alex Marks || Ep. 29

    The Training Project | Fitness Podcast

    Play Episode Listen Later Nov 19, 2025 51:34


    In this week's episode of The Training Project Podcast, Joe reconnects with London-based trainer and OYM Studio founder Alex Marks — more than a decade after they first met working at a boys' sports camp. Alex has built an incredible career spanning TV, entrepreneurship, and personal training, and his philosophy flips the script on what fitness really means.They dive deep into why “fat loss isn't the goal,” how empathy and communication shape coaching success, and why strength training is at the heart of longevity. From pre- and postnatal training to creating global fitness travel experiences with Surf Yoga Beer, Alex shares a refreshingly real take on what it means to help people live stronger, fuller lives.Why “fat loss” misses the point — and what the real goal should beHow to coach with empathy and build a lasting career in fitnessThe trap of exercise “entertainment” vs. real skill developmentThe rise of strength training for women and breaking the “skinny” mindsetThe power of teaching clients self-sufficiency instead of dependenceWhy in-person coaching still beats digital — and always willBuilding confidence through strength and the ripple effect beyond the gymThe story behind Alex's work with new moms and pre/postnatal fitnessFitness as connection: how Surf Yoga Beer is redefining wellness travelThe “Turn Left” philosophy — choosing growth over comfort“Fat loss is a great sales point — but real progress starts when we build strength, not just chase smaller numbers.”“Empathy and accountability outlast every trend in fitness.”“There's no substitute for human interaction — coaching in person is irreplaceable.”“Turn left. That's where growth happens.”Instagram: @on.your.marksStudio: OYM PT Studio – London, UKGlobal Fitness Adventures: Surf Yoga Beer

    The Human Upgrade with Dave Asprey
    The Tiny Implant Replacing Life-Changing Drugs | Biohacking Tools : 1365

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 18, 2025 56:04


    Bioelectronic medicine is changing how we treat inflammation, autoimmunity, and chronic disease, and this episode shows you exactly how nerve stimulation could redefine human performance, longevity, and brain optimization. You will learn how electricity, neurotransmitters, and targeted neural pathways can replace drugs, control inflammation, and help you hack the vagus nerve with precision instead of guesswork. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Kevin J. Tracey, MD, president and CEO of the Feinstein Institutes for Medical Research at Northwell Health, pioneer of vagus nerve research, and author of The Great Nerve. He is one of the world's most cited scientists in inflammation and neuroscience, and his discoveries created the field now known as bioelectronic medicine. He identified the therapeutic action of anti TNF antibodies, mapped the inflammatory reflex, and revealed how vagus nerve signaling controls immunity. With more than 450 scientific publications and over 120 U.S. patents, he is a trusted authority whose work drives the future of anti-aging, functional medicine, metabolism, and neural therapies. Dr. Tracey and Host Dave Asprey explore how the vagus nerve truly operates, why it contains 200,000 fibers with different functions, and what happens when you stimulate specific pathways that regulate inflammation, HRV, neurotransmitters, and immune signaling. You will learn how nerve impulses transmit information, how voltage gated ion channels shape behavior and biology, and why certain forms of stimulation create measurable improvements in mitochondria, metabolic control, sleep optimization, and emotional regulation. They break down the science behind surgical vagus nerve implants, focused ultrasound, gamma entrainment, cytokine control, and real neuromodulation. They also explore why cold plunging, breath work, HRV training, nootropics, and consumer devices vary so widely in their effects, and how to evaluate these tools with practical biohacking frameworks. You will hear what actually works, what remains experimental, and what the next decade of nerve based therapies could unlock for brain optimization, longevity, ketosis, fasting, supplements, and AI guided interventions in human biology. You'll Learn: • How vagus nerve stimulation reduces inflammation through the inflammatory reflex • Why bioelectronic medicine can replace drugs in autoimmune conditions • How nerve fibers relay electrical and chemical signals inside the body • Why cold immersion, breath work, and HRV training activate specific vagal pathways • How 40 hertz gamma entrainment may influence cognitive decline • Which stimulation methods have clinical validation and which do not • Why high vagal tone is linked to better metabolism, immunity, and emotional stability • What future nerve based technologies may unlock for human performance Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Kevin J. Tracey, vagus nerve stimulation, bioelectronic medicine, inflammatory reflex, SetPoint Medical, cytokine control, neuromodulation therapy, autonomic nervous system, HRV optimization, inflammation reduction, rheumatoid arthritis treatment, focused ultrasound therapy, gamma entrainment, mitochondrial signaling, anti-aging science, neural pathway hacking, functional medicine research, immune system regulation, brain and body performance, human longevity science Thank you to our sponsors! -AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. -MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Calroy | Head to https://calroy.com/dave for an exclusive discount Resources: • Learn More About Kevin's Work: https://feinstein.northwell.edu/institutes-researchers/our-researchers/kevin-j-tracey-md • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:12 - Bioelectronic Medicine 3:23 - FDA Approval 6:48 - RA Treatment Explained 11:35 - Vagus Nerve Function 15:12 - External vs Implanted Stimulation 18:06 - Focused Ultrasound 26:11 - Ear Stimulation Science 30:51 - Clinical Evidence 37:10 - Alzheimer's Link 42:15 - Future Applications 46:48 - Cold Exposure Effects 53:51 - Common Misconceptions 55:38 - Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Mind & Matter
    How & Why Mitochondria Make Their Own Fat | Sara Nowinski | 263

    Mind & Matter

    Play Episode Listen Later Nov 18, 2025 57:04


    Send us a textMitochondrial fatty acid synthesis is a little-known but essential pathway that supports energy production and metabolic health.Summary: Dr. Sara Nowinski explains how mitochondria not only burn fuels to make ATP but also synthesize their own fatty acids inside the matrix; this conserved pathway produces lipoic acid (an essential enzyme cofactor) and longer-chain fats required for proper assembly of the electron transport chain, and disrupting it impairs respiration, glucose handling, and insulin sensitivity while enhancing it appears protective against obesity and heart injury.About the guest: Sara Nowinski, PhD is an assistant professor in the Department of Metabolism and Nutritional Programming at Van Andel Institute in Grand Rapids, Michigan, where since 2021 she has led a lab focused on mitochondrial biology and the mitochondrial fatty acid synthesis (mitoFAS) pathway.Topics Discussed:Basic mitochondrial energy production: food → pyruvate/fatty acids → acetyl-CoA → TCA cycle → electron transport chain → ATPMitochondrial fatty acid synthesis (mitoFAS): a bacterial-like pathway that builds fats on an acyl carrier protein inside the matrixLipoic acid: an 8-carbon fatty acid made only by mitoFAS, covalently attached to key enzymes (e.g., pyruvate dehydrogenase); cannot be rescued by supplements for cofactor useLonger mitoFAS products (14–16 carbons) stabilize electron transport chain assembly factors, explaining why pathway loss collapses respiration even when lipoic acid is intactKnocking out mitoFAS causes embryonic lethality, insulin resistance, poor glucose homeostasis, and a rare neurodegenerative disorder (MEPAN syndrome)Overexpressing the mitochondrial acyl carrier protein protects mice from diet-induced obesity, insulin resistance, and cardiac injuryMuscle cell differentiation fails without mitoFAS, hinting at a role in tissue development and repairPractical Takeaways:Supplemental lipoic acid can act as an antioxidant but cannot replace the lipoic acid your mitochondria must make themselves for enzyme function.Severe impairment of mitochondrial fatty acid synthesis is linked to insulin resistance and metabolic disruption, suggesting mitochondrial health (beyond just biogenesis) matters for glucose control.Lifestyle or future therapies that boost overall mitochondrial function (e.g., exercise via PGC-1α) may indirectly support tSupport the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Special sale Nov 10 - Dec 1: Lumen is half off ($599 → $299), and MINDMATTER gets another 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, get $100 off for AquaTru Carafe, Classic and Under the Sink Units, and $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

    Carrots 'N' Cake Podcast
    Ep313: Protein Timing, Low-Carb Myths & Metabolic Truths with Mikki Williden, PhD

    Carrots 'N' Cake Podcast

    Play Episode Listen Later Nov 18, 2025 51:00


    In this episode, Tina chats with Mikki Williden to explore essential nutrition strategies for women in midlife. She discusses the pitfalls of common dietary habits and the importance of balancing fat loss goals without compromising hormones or energy levels. Mikki explains what 'metabolic flexibility' means and offers tips on shifting the body to burn more fat efficiently. She dives into how much protein women need for muscle maintenance, weight loss, and metabolism optimization, detailing how to distribute protein throughout the day for best results. She also discusses the concept of 'low carb' diets and their place for women over 40, offer strategies for fueling workouts, and highlight key supplements that support hormone balance and metabolic health. She also shares her insights on nutrition myths that need to be dispelled and offers practical advice for improving overall health. Here's what you'll learn: - The most common nutrition mistakes women in midlife make and how to fix them - How to balance fat loss goals without tanking your hormones or energy - What “metabolic flexibility” really means and how to shift your body to burn more fat - How much protein women truly need for muscle, weight loss, and metabolism - How to distribute protein across the day for optimal recovery and results. - What “low carb” really means and if it has a place for women over 40 - Smart strategies to fuel workouts and recover faster - The key supplements that support hormone balance, energy, and metabolic health - The one nutrition myth she wishes every woman would let go of for good Connect with Tina Haupert: https://carrotsncake.com/ Facebook: Carrots 'N' Cake https://www.facebook.com/carrotsncake Instagram: @carrotsncake https://www.instagram.com/carrotsncake YouTube: Tina Haupert https://www.youtube.com/user/carrotsncake About Tina Haupert: Tina Haupert is the owner of Carrots ‘N' Cake as well as a Certified Nutrition Coach and Functional Diagnostic Nutrition Practitioner (FDN-P). Tina and her team use functional testing and a personalized approach to nutrition to help women find balance within their diets while achieving their body composition goals. Connect with Mikki Williden, PhD: https://www.mikkiwilliden.com/about Facebook: https://www.facebook.com/mikkiwillidennutrition/ Twitter: https://twitter.com/MikkiWilliden Instagram: https://www.instagram.com/mikkiwilliden/ About Mikki Williden, PhD: Mikki Williden, PhD graduated with a Bachelor of Science in Human Nutrition, and a Bachelor of Physical Education from the University of Otago, Dunedin, New Zealand. She attained her Masters in Science (Human Nutrition) with First Class Honours in 2003, focusing on the development of a childhood obesity prevention programme. As a registered nutritionist, She has been privately consulting with clients since 2006 and has worked with a vast number of people with different health and performance goals. In 2011, she obtained my PhD after completing her doctoral thesis in health and productivity in the New Zealand workforce. She hosts a twice-weekly podcast, Mikkipedia, which dives deep into the topics of nutrition, longevity, fitness, and health, and is the creator of Mondays Matter, a successful fat loss group programme that utilises evidence-based techniques to support body composition goals and has helped thousands of people. She is the Director of Nutrition for SFuels, an innovative sports nutrition company that advocates for right fuel, right time. She has worked with world-class athletes and some notable New Zealanders, helping them achieve their nutrition-related goals, including Nigel Latta (on The Sugar episode) and Simon Gault (on the documentary series Why are we Fat?). She is passionate about helping to translate science into practice to help people meet their health goals, and is a regular contributor to digital and media platforms, as well as having an active social media presence.

    Le Wake-up mix
    L'intégral 18/11/2025 par DJ Serom : RnBoi, Hamza, Montell Jordan, Sean Paul, T.O.K., Remy Ma, Fat Joe...

    Le Wake-up mix

    Play Episode Listen Later Nov 18, 2025 60:51


    durée : 01:00:51 - Le Wake-up mix - Le Wake-Up Mix, c'est tous les jours dès 07h sur Mouv' !! Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.

    Vanessa G Fitcast
    Ep. 250 Rest vs. Movement - Which do You Need? Here's How to Know

    Vanessa G Fitcast

    Play Episode Listen Later Nov 17, 2025 23:13


    If slowing down feels wrong but your body is begging for rest, this episode is for you. In this episode, I'm talking to the woman who has always been the go-hard achiever — the early workouts, the hustle, the I-don't-need-rest mindset.  But now your body feels like it's pushing back, and slowing down feels uncomfortable or even scary. I've been there, and I want to help you make sense of what your body is trying to say. Instead of guessing or feeling guilty,  I'm giving you a simple, practical five-question check-in to help you know whether your body needs rest or whether gentle movement will actually make you feel better. Because in a healing season, both rest and movement are powerful — it's just about choosing the right one for the day you're in.  You'll learn why the signals you're feeling are a sign of recovery, not failure. I'll walk you through what this looks like in different phases of healing — from burnout, to rebuilding, to thriving again. We'll also talk about the mental side of this: letting go of the belief that discipline only counts when you push harder.  Resting doesn't make you weak. It makes you wiser. And the more you listen to your body, the faster your energy, hormones, and confidence return.  By the end of this episode, you'll have a tool you can use anytime you're unsure of what your body needs. This is how you build trust with yourself again — one decision at a time. So take a breath, tune in, and let's help your body feel safe and strong again.  Time Stamps: (1:17) Mood Lighting(2:02) Pulling Back From Exercise(5:47) Movement and Discipline(8:14) Your Hormones Are Recalibrating(9:59) #1: How Did I Sleep Last Night?(11:57) If You're Averaging 5-6 Hours of Sleep A Night(13:12) #2: My Stress Level From 1-10(14:32) #3: How Does My Body Feel Physically?(16:00) #4: What's My Emotional State?(17:41) #5: How Do I Think I'll Feel After?(21:56) Save This One For The Future---------------------Find Out More Information on Vital Spark Coaching---------------------Follow @vanessagfitness on Instagram for daily fitness tips & motivation. ---------------------Download Our FREE Metabolism-Boosting Workout Program---------------------Join the Women's Metabolism Secrets Facebook Community for 25+ videos teaching you how to start losing fat without hating your life!---------------------Click here to send me a message on Facebook and we'll see how I can help or what best free resources I can share!---------------------Interested in 1-on-1 Coaching with my team of Metabolism & Hormone Experts? Apply Here!---------------------Check out our Youtube Channel!---------------------Enjoyed the podcast? Let us know what you think and leave a 5⭐️ rating and review on iTunes!

    The Mind Muscle Connection
    Q&A - Aggressive Fat Loss For Women, DB vs Barbell RDL, How Long In Fat Loss and more| Ep 676

    The Mind Muscle Connection

    Play Episode Listen Later Nov 17, 2025 31:03


    Welcome to the Mind Muscle Connection Podcast!In this Q&A episode, I'm diving into Aggressive Fat Loss For Women, DB vs Barbell RDL, How Long in Fat Loss and more.I break down how long someone should realistically stay in a fat loss phase (especially if they have more to lose), when to take a break, how aggressive is too aggressive when dieting for women, and whether dumbbell or barbell RDLs are “better.” I also share a bit about why I'm switching back to four days of lifting and what's changed in my own training priorities lately.If you've been second-guessing your fat loss timeline or wondering if you need to push harder or pull back, this episode is worth a listen!Let's talk about:Fat loss duration for higher body fatHow to know when to take diet breakHow aggressive should fat loss be for women?Barbell, Dumbbell or RDL4 days of liftingFollow me on Instagram for more information and education: @jeffhoehn_FREE 30 Min Strategy Call: HEREBody Recomp Checklist 2.0 HERENutrition Periodization Masterclass: HEREHow You Can Work With Me?: HERECoaching application: HERE

    Chubs Gone Wild!
    ChubsGW616: Huge Hawaiian Hungarians

    Chubs Gone Wild!

    Play Episode Listen Later Nov 17, 2025


    Intro; Holidays, Birthdays, Feedbag, Chub Hugs, Nostalgia, What’s In Your Lunchbox?, Hey Chubs, Advice; TV and Movie Reviews, and lots of chub talk! chubsgonewild@gmail.com Subscribe in iTunes! Right Click Here To Download ChubsGW616

    No Special Characters
    NSCP 177 | HIGH CALORIE HUMAN

    No Special Characters

    Play Episode Listen Later Nov 17, 2025 93:55


    On today's episode  I speak about receiving a core memory trigger while watching stand up. I forget that our parents didn't have youtube or even needed youtube because they had us, we were the entertainment. I might have also triggered a core memory for an innocent bystander because i recited a joke terribly. A joke about body figures lead to more people thinking I'm sexist, but i guess that's better than being a plagiarizer. I then speak on an after work hang out with co workers, and dealing with the long arm of the law after festivities. Fun times, fun times.(00:00 - 29:28)On the movie review section we talk about film movies and other things and give the worse takes. This week i speak about  “ Predator : Bad Lands, this movie was awesome. Let me relax it was good for what it was, it was on  and off lore but in a different way that was not the worse thing. This movie let us know that we really don't stand a chance against them one on one without weapons. The world was a predator in its own way, nothing on that planet was meant to be peaceful, everything is on attack mode. But what makes this movie dope we finally get to see things from the predators prospective. It was pretty dope, y'all should check it out.(29:29 - 42:58)I then jump into The Cool Report  where we discuss Donaldson Trump new financial proposals for all and it has us all scratching our heads. 50 year mortgage loans and 15 year auto loans. The math is not mathing and they're trying to tell us the answer is pretty simple PEMDAS. From there he goes on to tell us that America does not have a fat person ban, but do. Fat people from outside of the US are not welcome until they get in shape like I. Then we get into Walmart doing Walmart things, like selling racist clothing along side with essentials, only in America. (42:59 - 01:04:15)We then step into a segment where the listeners ask me 3 questions about myself or just randomness. A character wants to know what do i know about seasonal depression and too stop appropriating it, but i had to let them know what time it is. I live this life daily not seasonal. I then get asked about my latest hot take and it involves YNs and LBGTQ+. You tell me if my take is too far out there. Another character wants to know how i feel about the new AI app out now. It takes the likeness of people that you upload to servers, but most people are using decease folks, i blame Ironheart.   (01:04:16 - 01:19:32)Then we have 2 fans ask us a questions for PTL where we get asked the tough questions where we place ourselves in their shoes. A lover wants to know is this tough love or just love that's tough? His partner wants him to lose weight, so she's taking away his only organic meal, she is putting the kitty away and he's going to feel it, not really but you get it. Another lover cooked himself for answering a dumb hypothetical his girl presented. Now he finds hisself in the dog house, but with internet connection so he's not that bad. I could only ridicule him for answering honestly we all know the answer except for your girl.(01:19:33  - 01:31:07)THE FINThanks to everyone that shows us love and wish y'all the best on the journey called life. (01:31:08 - 01:33:55)please continue to like, share, comment and subscribe.PEACE OUT!!!! For questions to be answered on Part time lover please email @nospecialcharacterspod@gmail.comTIME CODEINTRO/ WHAT'S NEW - 00:00MOVIE REVIEW - 29:29THE COOL REPORT - 42:59ASK ME A QUESTION - 01:04:16PART TIME LOVER - 01:19:33OUTRO - 01:31:08

    The Human Upgrade with Dave Asprey
    The Boring Secret Behind Celebrities Who Don't Age : 1364

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 16, 2025 14:50


    What if the secret to living longer wasn't locked in a lab, but hiding in plain sight? And what could lobsters possibly teach us about staying young?Scientists have discovered a remarkable connection between an ancient practice and our cellular aging process - one that celebrities and longevity researchers are quietly using to their advantage. It involves an enzyme in your body that most people don't even know exists, yet it plays a crucial role in how fast (or slow) you age.The twist? You can activate it in just 10 minutes a day, no prescription required.Curious about the biological "switch" that might help you turn back your cellular clock? The answer might surprise you...*Chapters*0:00 – Introduction0:46 – Lobsters and Human Longevity Connection1:14 – Understanding Telomeres and Aging2:26 – How Lobsters Defy Aging3:32 – Rethinking Aging Biology4:53 – The Telomerase Challenge6:43 – Natural Ways to Protect Telomeres9:33 – Meditation's Role in Anti-Aging11:04 – Different Meditation Techniques13:19 – Benefits and Long-Term EffectsResources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com ADS/SPONSORSBodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off.AirDoctor | Go to https://airdoctorpro.com/daveasprey and save up to $300 on Air Purifiers.Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast:https://www.instagram.com/TheHumanUpgradePodcast/https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    The Brian Turner Show
    Brian Turner Show (on East Village Radio), November 15, 2025

    The Brian Turner Show

    Play Episode Listen Later Nov 16, 2025 119:15


    eastvillageradio.com, brianturnershow.comMEN WITH NO I.Q.'S - Love Me In Flames - Sexational Teen (1987, re: Nuthin, 2025)PILL MILL - Trimming the Fat - s/t (Neon Taste, 2025)SIKPHUKZ - Punk Is Shit - 7" (1980, re: Supreme Echo, 2025)SCRABBLED - Masochistic Love - Plough Through The Rust (Wormwood Grasshopper, 2025)ACE IS THE PLACETHE HEADS - Chipped - Reverberations Vol. 7 (Feeding Tube, 2025)ATOL ATOL ATOL - Płytki Sen - Dron Dron Dron (cs, Syf, 2025)PUPPET WIPES -  The Unabomber Used To Come And Dance At Events - Live Inside (Siltbreeze, 2025)JAYDAWN & WUKIR SURYADI - Palugon (Battlefield) - Pucung, Pangkur Jeung Hujan Bedog (WV Sorcerer Productions, 2025)THE FALL - Rowche Rumble (Live JB's, Dudley UK 79)NERVOUS NORVUS - Transfusion - 7" (Dot, 1956)LOS LLAMARADA - Mystery Star - Deep Dark Vast (cs, C/Site, 2025) 73년의 웨더비 -  미국 개를 위한 수소폭탄 - 영향력을 위해 북한 출신인 척하다 (Neon Doom, 2025)ODIV - Dôbbâ - Shelâl (Zabte Sote, 2025)CADAVER DOG - Repulsed - Barbaric Nature (Youth Attack, 2025)GRINNING DEATH'S HEAD - Prey - s/t (Youth Attack, 2025)ZULI - Sawany Bas ثواني بس - Swag Lee: Habibi Loops Vol. II (BC, 2025)AD AGENCY - Mountain Song - V/A: Kwashiorkor Presents (cs, Infinite Expanse, 2025)A DOG REPUBLIC - Excerpt - Demonstrations #5.2 (Ultra Eczema, 2023)SCREW - Devil's Hour - 10" (1969, re: Shagrat, 2007)MIDNIGHT MINES - Death Pt. II - Feel I'm Slipping Away Now (Minimum Table Stacks, 2025)SKY SUNLIGHT SAXON & THE STARS NEW SEEDS BAND - Starry Ride - Starry Ride (Psycho, 1984)ONYON - Schiefe Bahn - Pale Horses (Mangel, 2025)HAYWARDxDALEK - Re-Evolution - HAYWARDxDALEK (Relapse, 2025)JAIMIE BRANCH - Birds of Paradise - Fly Or Die II: Birds of Paradise (International Anthem, 2019)KELAN PHIL COHRAN & LEGACY - White Nile - African Skies (1993, re: Listening Position, 2025)LUCIANA BASS - Desatornillándonos - Desatornillándonos (Relative Pitch, 2024)SELYR - Live 11/15/2025 (NL)

    fat nl nuthin brian turner syf east village radio kelan phil cohran
    Alain Elkann Interviews
    Architecture as a Language - Sean Griffiths on Cities, Power & Design - 260 - Alain Elkann Interviews

    Alain Elkann Interviews

    Play Episode Listen Later Nov 16, 2025 41:17


    MODERN ARCHITECT. Sean Griffiths is Professor of Architecture at the University of Westminster and former Visiting Professor of Architectural Design at Yale University. His current architecture and design practice Modern Architect was founded in 2014 and has worked largely on residential, commercial and public art projects. Previously Sean Griffiths was a founding director of the internationally renowned art/architecture practice FAT, where he won many design awards. FAT represented the UK at the Venice Architecture Biennale in 2014. "I was really thinking I would  pursue a career as an artist" "The idea that you make architecture as a sort of branding jewel that you place in a city is not something that I particularly love" "We use language to help us navigate the world, and architecture also creates patterns that help us navigate the world"

    The Human Upgrade with Dave Asprey
    Biohacking News Weekly Update : 1363

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 14, 2025 10:00


    This episode covers: • Cocoa Extract Cuts Heart Deaths A massive COSMOS trial found that older adults taking high flavanol cocoa extract daily saw a 27 percent reduction in cardiovascular deaths along with drops in inflammation markers like HSCRP. Women showed unique anti inflammatory cytokine shifts, pointing to a broader longevity effect. Dave explains why cocoa extract is becoming a foundational nutrient for vascular health rather than a dessert ingredient. Source: https://www.sciencedaily.com/releases/2025/09/250926135957.htm • AI Stethoscope for Home Diagnostics Lapsi Health's Keikku 2.0 just became the first FDA cleared AI powered digital stethoscope for both clinicians and home users. It records heart and lung sounds, analyzes them instantly, and flags early warning signs before symptoms appear. Dave breaks down why tools like this move you from reactive to predictive medicine and why they belong in every quantified self toolkit. Source: https://www.prnewswire.com/news-releases/lapsi-health-unveils-keikku-2-0-worlds-first-fda-cleared-digital-stethoscope-with-integrated-ai-scribe-302585083.html?utm_source=chatgpt.com • Beef Organ Supplements Surge Beef organ supplements have exploded more than 8,000 percent this year, driven largely by women reporting improvements in energy, hormones, mood, and skin. Liver, kidney, and heart deliver vitamin A, heme iron, B12, copper, and choline that modern diets often lack. Dave covers sourcing concerns, purity standards, and why this shift reflects a move from fear based nutrition to evolutionary nutrition. Source: https://www.verywellhealth.com/beef-organ-supplement-11710185?utm_source=chatgpt.com • Spirulina for Collagen and DNA Protection New research highlights spirulina's ability to support collagen production, reduce oxidative stress, protect DNA, and improve glucose and lipid balance. It is becoming a staple of eco focused anti aging routines and is driving the viral green stacking trend with chlorella and chlorophyll. Dave explains why spirulina functions as a clean daily defense against oxidative stress. Source: https://www.news-medical.net/news/20250707/Is-Spirulina-the-Next-Anti-Aging-Superfood.aspx • Health Data Privacy Reform A new Senate bill aims to extend HIPAA level protections to wearables, genomic tools, glucose monitors, and wellness apps. The goal is to give users control over who sees their biometrics, how they are stored, and whether they can be sold. Dave outlines why this matters for anyone using Oura, Whoop, CGMs, or genetic testing and why your biology should belong to you and not the cloud. Source: https://natlawreview.com/article/federal-healthcare-update-november-7-2025 All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cocoa extract, flavanols, heart health, nitric oxide pathways, COSMOS trial, AI stethoscope, digital diagnostics, Keikku device, predictive health tech, beef organ supplements, women's hormonal health, nutrient dense foods, ancestral nutrition, spirulina benefits, collagen support, oxidative stress defense, green stacking, chlorella pairing, DNA protection, wearable privacy laws, HIPAA reform, biometric data rights, longevity news, biohacking updates Thank you to our sponsors! Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Intro 0:19 – Cocoa Extract & Heart Health 1:52 – AI Digital Stethoscope 3:01 – Beef Organ Supplements 4:24 – Spirulina for Longevity 5:42 – Substack Announcement 6:53 – Health Data Privacy Reform 8:23 – Weekly Upgrade Protocol 9:46 – Outro See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Lean Body Buffalo Podcast
    The Real Reason Your Clothes Don't Fit the Same Way

    Lean Body Buffalo Podcast

    Play Episode Listen Later Nov 14, 2025 4:53


    Episode Summary:Frustrated because your favorite clothes don't fit the same way they used to, even though the scale hasn't moved much? You're not imagining it - and you're not alone. In this episode, Brian reveals the hidden truth about what's really happening to your body after 40 and why traditional weight loss approaches actually make the problem worse. Discover why body composition matters more than the number on the scale and how to get your confidence back.Detailed Show Notes:[0:00 - 0:30] Hook & IntroductionThe frustrating reality of clothes that don't fit the same wayWhy this happens even when your weight stays the same[0:30 - 1:30] The ProblemThat Monday morning wardrobe struggle we all knowHow 5 pounds can completely change how clothes fitThe emotional impact of feeling uncomfortable in your own clothes[1:30 - 3:15] The Science Behind the ChangesBody composition changes after 40: losing muscle, gaining fatWhy muscle takes up less space than fat (18% difference)Hormonal changes and fat redistribution patternsHow posture and core strength affect clothing fit[3:15 - 4:15] Why Traditional Approaches FailWhy focusing only on weight loss makes the problem worseHow crash dieting accelerates muscle lossThe cardio trap that breaks down muscle tissueWhy you can be lighter but still feel worse in your clothes[4:15 - 5:00] The Solution & Call to ActionFocus on body composition instead of weight lossStrategic strength training vs. endless cardioThe importance of adequate protein for muscle rebuildingFree VIP Pass: 3 personal training sessions + 30-day fat burning meal planVisit: www.fatlossafter40.comKey Takeaways:✓ Your clothes fitting differently isn't about weight - it's about body composition✓ Muscle loss after 40 changes your body shape even at the same weight✓ Fat takes up 18% more space than muscle tissue✓ Traditional weight loss methods accelerate the problem✓ Strategic strength training and proper nutrition can reverse these changesResources Mentioned:Free VIP Pass: www.fatlossafter40.com

    The Human Upgrade with Dave Asprey
    How to Build Muscle WITHOUT Lifting! Biohacker Longevity : 1362

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 13, 2025 63:49


    Your workouts may be doing less than you think, and science now proves why. This episode reveals how to build muscle, improve metabolism, and extend longevity in a fraction of the time using blood flow restriction training and intermittent hypoxia. You'll learn how to hack your mitochondria for faster recovery, stronger hormonal balance, and better brain performance without the burnout of high-intensity training. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Dr. Sten Stray-Gundersen, PhD, CSCS, one of the world's leading experts on blood flow restriction (BFR) training and metabolic physiology. With over a decade of research and teaching experience, Dr. Stray-Gundersen has explored how BFR and intermittent hypoxia can improve cardiovascular health, metabolism, and recovery. After earning his doctorate in Exercise Physiology from the University of Texas at Austin, he now serves as an Assistant Professor at the University of South Carolina, where he studies vascular adaptations, cognitive performance, and ergogenic aids. He's also a B Strong master trainer, developing individualized BFR protocols for athletes, military professionals, and everyday people looking to optimize human performance. Together, Dave and Sten uncover how BFR and oxygen cycling unlock powerful adaptations in the body's vascular, metabolic, and hormonal systems. You'll learn how strategic stress signals can trigger nitric oxide production, enhance glucose uptake, improve insulin sensitivity, and supercharge mitochondria for better energy and anti-aging benefits. They also explore how these methods can naturally boost testosterone, growth hormone, and even libido, all while protecting the nervous system and improving recovery. This episode dives deep into biohacking, functional medicine, and smart exercise efficiency, from Zone 2 and REHIT training to nitric oxide signaling, fasting, nootropics, and precision supplementation. Whether your goal is longevity, strength, or sharper cognition, this conversation shows you how to get maximum results with minimal time using the principles of Smarter Not Harder. You'll Learn:• How intermittent hypoxia works at the level of partial pressure and why altitude acclimation upgrades mitochondria and performance• Why hypoxia and muscle contraction increase glucose uptake independent of insulin and improve insulin sensitivity• How blood flow restriction (BFR) accelerates fatigue with light loads to drive hypertrophy, strength, and vascular adaptations• How BFR and hypoxia influence testosterone, growth hormone, nitric oxide, and libido through short, targeted stress• The roles of ENOS, INOS, and NNOS in nitric oxide signaling and what that means for circulation and brain perfusion• Who benefits most from BFR, including athletes, rehab patients, and older adults who cannot lift heavy• Why BFR produces systemic and “proximal” gains, including carryover to glutes and upper body during lower limb training• How to stack BFR with Zone 2, REHIT, and vibration plates for VO2 max, muscle, and time efficiencyDave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Sten Stray-Gundersen, blood flow restriction training, B Strong, intermittent hypoxia, mitochondrial function, nitric oxide production, VO2 max, metabolic efficiency, vascular health, testosterone boost, growth hormone release, anti-aging performance, exercise recovery, glucose metabolism, functional medicine, biohacking fitness, REHIT training, Zone 2 optimization, strength and longevity, human performance science Thank you to our sponsors! -KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off. -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. -Leela Quantum Tech | Check out all HEAL360 products and research and get 10% off at https://leelaq.com/DAVE. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Use code DAVE10 to get a discount on a BFR band today: https://shopify.bstrong.training/products/b-strong-training-system?ref=dave%2F • Dive deeper in Sten's work at: https://bstrong.training/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:25 - Guest Intro 5:40 - Intermittent Hypoxia & Altitude Acclimation 12:11 - Introduction to Blood Flow Restriction (BFR) 22:53 - Systemic Benefits & Who Can Use BFR 30:23 - BFR Effects on Hormones & Libido 40:37 - Nitric Oxide & Vascular Health 48:15 - Zone 2 Training with BFR 54:00 - Advanced Protocols: Stacking BFR 59:15 - Cognitive Enhancement & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Rock School
    Rock School - 11/23/25 (Mtv is Dying)

    Rock School

    Play Episode Listen Later Nov 13, 2025 40:25


    "Video may have killed the radio star but streaming and individual choices in music killed the video. Paramount Global has begun shutting down Mtv channels in Europe and reports are that soon it will come to the United States. Mtv is 44 and it looks like it may not make it to 45. "

    covid-19 united states christmas music women death live tiktok halloween black ai donald trump europe english school social rock coronavirus media japan politics dreams young sound song video russia corona ukraine stars elon musk holidays tour guns killers night fake oscars dead lockdown grammy political stage court restaurants ending ufos quit nfts fight series dying beatles streaming television kansas city panic concerts monsters believing saturday night live mtv joe rogan passing moral killed elvis taught presidential logo trigger fund fights naturally conservatives apollo tap died roses grave playlist rockstars rolling burns stones dates finger marijuana phillips simpsons stadiums psychedelics memoir poison lawsuit serial jeopardy bots nirvana backup liberal tariffs managers fat wildfires copyright bugs tours trilogy lsd bus logos inauguration richards petty prom eq boo 2022 johnny cash unplugged mythology motown wrapped rock n roll bug parody deezer commercials halifax ska 2024 jingle strat singers rocketman library of congress alley spears chorus yacht robbers lovin autoimmune slander ramones trademark biscuit mccartney papas ringo moves flute edmund revived graceland defamation cranberries robert johnson trademarks lynyrd skynyrd dire straits spinal leap year live aid torpedos groupies cryptozoology booed spoonful wasserman sesame conservatorship stone temple pilots autotune biz markie moog razzies binaural roadie cbgb jovan midnight special 1980 public broadcasting schoolhouse rock dlr john lee hooker zal busking summer songs libel posthumous idiom bessie smith loggins paramount global busker dockery payola pilcher pricilla contentid journeymen 3000 jock jams hipgnosis bizkit rutles zager no nukes journe alone again rock school blind willie mctell metalica vanilli maxs marquee club sherley mitchie soundscan at40 alago kslu mugwumps
    Aye Yo Fat Girl!
    FAT? SO!

    Aye Yo Fat Girl!

    Play Episode Listen Later Nov 13, 2025 9:07


    Let's talk about it — the word FAT.

    Learning to Glow: Tips for Women's Health, Optimal Wellness and Aging Gracefully
    148: 5 Tools to Tackle the Busy Season and Keep Your Energy Up

    Learning to Glow: Tips for Women's Health, Optimal Wellness and Aging Gracefully

    Play Episode Listen Later Nov 12, 2025 30:55


    Send us a textThis time of year can be beautiful—but also exhausting. I'm sharing five ways I'm supporting my energy, both mentally and physically, so I can show up as my best self. These tools are realistic, grounding, and easy to fit into your day. I am also navigating my health and wellness while also being busier than normal. And sharing ways I am prioritizing that in this busy season of life! Enjoy! ✨ Join the Simply Jess Skincare newsletter for this week's episode link and upcoming holiday deals! Go to the website (click here) and be the first to know of our once a year specials! Find Jess below!Website: Simply Jess Skincare SIMPLY JESS SKINCARE:Each and every product is naturally derived, highly concentrated and most importantly, super performing! Every product was born out of a need to have a truly pure product that met my high standards for efficacy. Subscribe to Our Newsletter! You can take 20% off Your Order of our all natural skincare line with code: PODCAST Shop Now! Favorite Supplements for Health and Fat loss: Click HERE My favorites are the Power Greens, Digestive Enzymes and Brain Power Mushroom Coffee-15% off with Code: SIMPLYJESSSKINCARE15 Click HereEmail Us! jess@learningtoglow.comFollow us! Instagram Tik Tok

    Aye Yo Fat Girl!
    Numbers Don't Lie

    Aye Yo Fat Girl!

    Play Episode Listen Later Nov 12, 2025 38:48


    Men Lie, Women Lie, Numbers Don't Lie!

    The Human Upgrade with Dave Asprey
    Why Motivation DOESN'T Work | Mental Biohacks : 1361

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 11, 2025 39:28


    True transformation doesn't come from motivation. It comes from rewiring your mind, reshaping your beliefs, and mastering your perception of reality. This episode reveals how to stop chasing short bursts of inspiration and start creating sustainable change in your thoughts, energy, and biology. You'll learn how belief, emotion, and neuroplasticity shape human performance, longevity, and resilience—and how to reprogram them for lasting results. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with David Bayer, one of the greatest personal growth teachers of our time. His podcast A Changed Mind reaches over 1 million listeners each month, and his event Powerful Living Experience Live was named a top 3 personal development event by Inc. Magazine. His book A Changed Mind has transformed tens of thousands of lives. David blends behavioral psychology, neuroscience, metaphysics, and consciousness theory into practical frameworks that help people rewire their brains and reengineer their reality. He is an entrepreneur, business strategist, keynote speaker, and mentor to some of the world's most influential entrepreneurs and creators. Together, Dave and David explore how motivation is just a microdose of transformation and why true change requires aligning your perception with how reality actually works. They break down the science behind belief, energy, and consciousness, connecting these ideas with biohacking, supplements, functional medicine, and brain optimization. You'll Learn:• Why motivation is only a temporary fuel and how to create lasting transformation• How to test your beliefs against reality and rewire the mind through awareness• The difference between absolute truth and personal truth in consciousness work• Why suffering and challenge are essential for growth and resilience• How to build faith as a biological and psychological muscle• How early trauma programs limiting beliefs and emotional patterns• The four layers of resistance that block personal transformation• Why forgiveness and self-love are essential to dissolving trauma• How perception literally shapes your experience of reality• Practical tools to align your consciousness for high performance and peace Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: David Bayer, A Changed Mind, Powerful Living Experience, belief systems, consciousness theory, neuroscience, behavioral psychology, personal growth, trauma transformation, resilience training, perception shift, motivation vs transformation, emotional regulation, mindset reprogramming, subconscious rewiring, neurohacking, cognitive performance, spiritual psychology, reengineering reality, high-performance mindset, sustainable change Thank you to our sponsors! -GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what's in your air. -Generation Lab | Go to http://generationlab.com/, use code Dave20 for $20 off, and see what your body's really doing behind the surface. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -LMNT | Get a free 8-count Sample Pack of LMNT with any drink mix purchase by going to https://drinklmnt.com/DAVE. Resources: • Learn more about David's work: www.davidbayer.com • Order David's book: https://www.amazon.com/Changed-Mind-Beyond-Awareness-Extraordinary/dp/1642939862 • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:25 - Why Motivation Isn't Sustainable 5:14 - Testing Reality as a Hypothesis 9:02 - Absolute Truth vs Personal Truth 11:02 - The Role of Suffering in Growth 15:01 - Building Faith as a Muscle 18:27 - Higher Power & Placebo Effect 20:38 - Believing Without Limits 24:27 - Transforming Childhood Trauma 27:34 - The Four Layers of Resistance 28:58 - Resentment & Forgiveness 33:09 - Turn the Other Cheek 39:28 - Entrepreneurs & Self-Sabotage 43:59 - Building Resilience in Business 46:00 - Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Chubs Gone Wild!
    ChubsGW615: Chubs Country

    Chubs Gone Wild!

    Play Episode Listen Later Nov 11, 2025


    Intro; Holidays, Birthdays, Feedbag, Chub Hugs, Nostalgia, What’s In Your Lunchbox?, Hey Chubs, Advice; TV and Movie Reviews, and lots of chub talk! chubsgonewild@gmail.com Subscribe in iTunes! Right Click Here To Download ChubsGW615

    Vanessa G Fitcast
    Ep. 249 Stop Rushing the Foundation: The Truth About Building a Body That Lasts

    Vanessa G Fitcast

    Play Episode Listen Later Nov 10, 2025 29:24


    We all want the dream body, but almost none of us want to slow down long enough to build the base it actually requires. In today's episode, I'm sharing one of the most important lessons I've learned as both a coach and a client: you can't build a strong, sustainable body without a strong foundation.  I use the analogy of building a dream home because just like a house needs a solid foundation before the walls go up, your body needs metabolic stability and healthy habits before you layer on intense training or dieting.  Most of us try to skip this part because we're in a hurry to see results.  I get it. I used to be the impatient one who wanted the plan, the strategy, and the visible progress right away. But rushing your transformation is the fastest way to end up starting over again and again.  In this episode, I break down what the “foundation phase” actually looks like, including how we assess metabolism using SHREDS and why stabilizing sleep, hunger cues, digestion, energy, stress, and recovery is non-negotiable.  I share why this phase can feel slow and why that slow work is what makes everything that comes after actually stick. I also walk through the three phases of a healthy nutrition journey and how to know which phase you're truly ready for.  This is about building a body that can handle real life. Vacations, busy seasons, holidays, stress, and everything in between. When your foundation is strong, you don't fall apart when your routine changes. You adapt and you bounce back.  If you've been feeling frustrated with slow progress, this episode may be the reframe you needed. Take a breath — you might just be pouring the concrete.  Time Stamps: (2:57) Next Stage of Homeownership (4:34) Building The Foundation (7:27) When I First Started My Fitness Journey (12:42) The Metabolic Assessment (19:42) Building The Walls Next (20:27) Vital Spark's 3 Phases (28:02) Please Share and Review---------------------Find Out More Information on Vital Spark Coaching---------------------Follow @vanessagfitness on Instagram for daily fitness tips & motivation. ---------------------Download Our FREE Metabolism-Boosting Workout Program---------------------Join the Women's Metabolism Secrets Facebook Community for 25+ videos teaching you how to start losing fat without hating your life!---------------------Click here to send me a message on Facebook and we'll see how I can help or what best free resources I can share!---------------------Interested in 1-on-1 Coaching with my team of Metabolism & Hormone Experts? Apply Here!---------------------Check out our Youtube Channel!---------------------Enjoyed the podcast? Let us know what you think and leave a 5⭐️ rating and review on iTunes!

    The Human Upgrade with Dave Asprey
    New Japanese Walking Hack Burns More Fat Than 10,000 Steps : 1360

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 9, 2025 9:22


    Discover a little-known Japanese walking technique that outperforms 10,000 steps a day. It boosts fat burning, lowers stress, improves mitochondria, and transforms your metabolism—all in just 15–30 minutes. Perfect for anyone who wants sustainable results without punishment workouts.*Chapters*00:00 – 00:46 My 300 lb journey & the surprising Japanese method00:46 – 01:54 Why mainstream fitness advice fails for fat loss01:54 – 02:37 Walking as the most underrated fat-burning tool02:37 – 04:03 The problem with steps & the Japanese breakthrough04:03 – 05:52 How interval walking works & how to do it05:52 – 09:12 Outdoor hacks that maximize resultsConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    The Human Upgrade with Dave Asprey
    Biohacking News Weekly Update : 1359

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 7, 2025 11:39


    Upgrade your biology in 10 minutes with this week's rundown from Dave Asprey. This episode breaks down the six biggest stories in biohacking and health tech, from sleep hormones to mitochondrial rejuvenation, giving you the data you need to live longer, think faster, and perform at your peak. This episode covers: • The Melatonin Heart Warning Everyone Missed A major new study from the American Heart Association reveals that long-term melatonin users face nearly twice the risk of heart failure and 3.5 times higher hospitalization rates. Once considered a harmless sleep aid, melatonin's hormonal effects may disrupt cardiovascular recovery, testosterone, and blood pressure regulation when used nightly. The takeaway: melatonin is a short-term circadian reset tool, not a forever supplement. Source: American Heart Association — newsroom.heart.org/news/long-term-use-of-melatonin-supplements-to-support-sleep-may-have-negative-health-effects • Bryan Johnson's Extreme Microplastics Detox Biohacker Bryan Johnson shared lab-verified results showing an 85% reduction in microplastics in his semen after one year of daily 200°F dry saunas followed by ice packs on the groin. It's not peer reviewed yet, but it'ssparking global discussion about environmental toxins, fertility, and detoxification. Whether or not you follow his protocol, this study highlights how widespread microplastics have become and how heat, sweat, and smarter exposure control may help fight back. Source: New York Post — nypost.com/2025/10/23/health/biohacker-bryan-johnson-got-rid-of-85-of-microplastics-from-his-semen • Urolithin A: The Mitochondrial Molecule That Strengthens Immunity A peer-reviewed human trial published in Nature Aging found that four weeks of daily Urolithin A (Mitopure®) supplementation improved immune function in adults aged 45–70, increasing youthful CD8 T-cells, natural killer cells, and mitochondrial performance inside immune cells. By triggering mitophagy, your body's cleanup process for old mitochondria, Urolithin A enhances energy, resilience, and immune strength. It's the clearest evidence yet that we can modulate immune aging through mitochondrial renewal. Head to timeline.com/dave to get 10% off your first order. Source: BioSpace — biospace.com/press-releases/timeline-continues-to-build-the-most-clinically-researched-longevity-products-targeting-immune-brain-and-muscle-aging • Google's New AI Model That “Talks” to Cells Google DeepMind and Yale launched Cell2Sentence-Scale, an open-source AI model that lets scientists query cellular pathways in natural language. The system can predict how cells transition from healthy to cancerous states and identify molecular switches that might reverse those changes. It's compressing years of biology into days and democratizing research for small labs and independent scientists alike. Isn't AI a beautiful thing? Source: Google DeepMind — blog.google/technology/ai/google-gemma-ai-cancer-therapy-discovery • Omega-3s Calm the Brain and the Temper A massive new meta-analysis of randomized controlled trials shows omega-3 fatty acids (EPA and DHA) reduce aggression by up to 28%. That includes both reactive anger and planned aggression. By lowering neuroinflammation and stabilizing cell membranes, omega-3s appear to balance dopamine and serotonin, proving that healthy fats aren't just heart food, they're emotional regulators too. Source: Science Alert — sciencealert.com/one-dietary-supplement-was-shown-to-reduce-aggression-by-up-to-28 • Chronic Fatigue Syndrome Finally Gets a Biomarker For the first time, researchers have developed a blood test that accurately identifies chronic fatigue syndrome (ME/CFS) using DNA methylation and micro-RNA expression patterns. This breakthrough distinguishes CFS from other autoimmune and viral conditions, marking a turning point for millions of patients long dismissed by traditional medicine. It's proof that data-driven diagnostics can transform how we understand mystery illnesses. Source: Science Daily — sciencedaily.com/releases/2025/11/251102205021.htm All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: melatonin heart risk, sleep hormones, microplastics detox, Bryan Johnson, Urolithin A, mitophagy, mitochondrial health, immune aging, DeepMind AI, cellular modeling, omega-3 aggression, neuroinflammation, chronic fatigue biomarker, ME/CFS test, biohacking news, longevity research Thank you to our sponsors! -LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser.-Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Intro 0:18 — Story 1: Melatonin & Heart Health 1:58 — Story 2: Microplastics Detox 3:39 — Story 3: Urolithin A & Immune Function 5:19 — Story 4: AI Cell Model 6:57 — Story 5: Omega-3 & Aggression 8:43 — Story 6: CFS Blood Test 9:59 — Weekly Upgrade Protocol See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Carnivore Conversations
    164. Carey & Maya: "I Woke Up in an 80-Year-Old Body"

    Carnivore Conversations

    Play Episode Listen Later Nov 7, 2025 42:01


    At just 15, Maya's body felt ancient—crippled by sudden arthritis, back pain, and joint stiffness. In this raw moment, she reveals the shock of waking up unable to move, and how it marked the beginning of her search for healing beyond conventional medicine.⏱️ Timestamps – “I Woke Up in an 80-Year-Old Body”00:46 – Isolation & Cravings Shift 02:11 – Meet Maya & Carrie 03:31 – COVID, Sports & Sudden Pain 05:01 – Medical Mystery & Sacroiliac Pain 06:31 – Carrie's Transformation & 50 lb Weight Loss 08:01 – Tracking, Data & Keto Shift 09:31 – Bodybuilding Past & Intermittent Fasting 11:01 – Maya's Influences: Jordan & Mikhaila Peterson 12:31 – Electrolytes & Mood Struggles 14:01 – Genetic Arthritis & Humira Experience 15:31 – Diet vs Medication: Choosing Carnivore 17:01 – Cultural Pressures in Japan 18:31 – Carrie's Maintenance & Dairy Challenge 20:01 – Fat vs Protein: Lifting & Satiety 21:31 – Skin, Psoriasis & Animal Fat Wins 23:01 – Japan Recap & Host Family Pressures 24:31 – Mental Health & Gen Z Epidemic 26:01 – Medical System & Carnivore Skepticism 27:31 – Sharing Stories & Facing Backlash 29:01 – Final Reflections & Empowerment Connect more with Dr. Kiltz:Website :https://www.doctorkiltz.com/Linktr.ee: https://linktr.ee/doctorkiltz?utm_source=linktree_profile_share<sid=f819f43c-43e2-45fe-ab8b-1c0af1962e2bKiltz's Mighty Tribe - Free membership and 30 Day Course:https://kiltz-mighty-tribe.mn.co/users/onboarding/choose_plan?plan_id=2184624&bundle_token=51d89e16bf2d37b1bb9945184e6b3256&prefer_signup=true&utm_source=manualKiltz Cups :https://kiltzcups.com/Doctor Kiltz Nutritional Solutions https://www.doctorkiltznutritionalsolutions.com/Instagram https://www.instagram.com/doctorkiltz/Tik tok:https://www.tiktok.com/@doctorkiltzFacebook:https://www.facebook.com/doctorkiltzAmazonhttps://www.amazon.com/Robert-Kiltz/e/B005EIXDWU%3Fref=dbs_a_mng_rwt_scns_shareBooks by Dr.Kiltzhttps://www.doctorkiltz.com/books-by-dr-kiltz/

    Over 40: Freakin Awesome | Mens Fitness After 40 | Healthy Habits | Workouts | Fat Loss | Testosterone

    Send a message/question here!https://ovr40.co/chat to set up a time to chat about your goals and challenges and coaching.In this episode, I break down which supplements are complete BS (testosterone boosters, multivitamins, fat burners, pre-workout supplements) and reveal the 5 best supplements men over 40 should actually take to boost testosterone naturally, build muscle after 40, improve sleep quality, reduce belly fat, and optimize health after 40.Supplements to AVOID After 40:Testosterone booster supplements (don't work, waste of money)Multivitamins for men (ineffective approach)Fat burner supplements (just expensive caffeine)Proprietary pre-workout supplement blends (underdosed ingredients)Anti Inflammatory supplements for men (your body breaks them down anyway)The 5 Best Supplements for Men Over 40:✅ Magnesium Glycinate (400mg before bed) - improve sleep quality, muscle recovery, natural testosterone support, reduce stress✅ Vitamin D3 (4000 IU daily) - boost testosterone levels, improve mood, support immune system, bone health for men over 40✅ Zinc Picolinate (30mg with food) - increase testosterone production, immune support, faster workout recovery, hormonal balance✅ Creatine Monohydrate (5g daily) - build muscle after 40, increase strength, improve brain function, cognitive health for older men✅ Ashwagandha (600mg evening) - lower cortisol levels, stress management, better sleep, support healthy testosterone levelsIf you're a man over 40 struggling with low energy, difficulty losing weight, declining testosterone, poor sleep, or lack of motivation to work out, these supplements actually work. After 16 years of coaching men in their 40s and 50s and trying every supplement on the market myself, these are the only ones that deliver real results for fat loss, muscle gain, hormonal health, and overall wellness after 40.Perfect for busy professionals, dads, and guys who want to get back in shape, lose belly fat, build lean muscle, and feel energized without complicated supplement stacks or expensive testosterone boosters that don't work.MORE FREE RESOURCES FOR MEN OVER 40:

    The Rush Hour Melbourne Catch Up - 105.1 Triple M Melbourne - James Brayshaw and Billy Brownless
    Fat's On Fire Quiz, Shaquille O'Neale, Jing - The Best of Triple M's Rush Hour - Friday 7th November 2025

    The Rush Hour Melbourne Catch Up - 105.1 Triple M Melbourne - James Brayshaw and Billy Brownless

    Play Episode Listen Later Nov 7, 2025 72:28


    We're looking back at our favourite moments from 2025, including John Kennedy Jr reflecting on the 1989 Grand Final where his Hawks defeated Billy's Cats. Greg Rust calls in to preview the Brazil F1 GP and talk about the legacy of Supercars Team Owner Garry Rogers, then we look back at Billy and Lehmo in the IKON Park commentary box - featuring a big red button. We look at JB's 2025 highlights, and we ask you if you've lost more Grand Finals than Billy. Billy gets you across all the sporting events you should know about this weekend, then we flash back to our interview with two Japanese Sumo Wrestlers. It's the final Fat's On Fire Quiz for 2025 - can Billy and the team nail all 20 questions? Then we look at all the times Billy has called JB the wrong name, we hear Billy's 1-on-1 interview with Shaquille O'Neale, and we finish with a fruity joke. See omnystudio.com/listener for privacy information.

    The Human Upgrade with Dave Asprey
    The Strange Science Behind Tylenol and Heartbreak | Daniel Amen : 1358

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 6, 2025 60:08


    Pain isn't just in your body, it's in your brain. In this groundbreaking episode, Host Dave Asprey sits down with Dr. Daniel Amen to reveal how emotional and physical pain share the same neural circuits and how you can rewire them for relief, resilience, and longevity. You'll learn practical tools to break the “doom loop” of pain, restore neuroplasticity, and retrain your brain for calm, healing, and high performance. This is essentiallistening for anyone ready to stop managing pain and start hacking it. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR The Washington Post called Dr. Daniel Amen the most popular psychiatrist in America. He is a former infantry medic and board certified child and adult psychiatrist who trained at the Walter Reed Army Medical Center in Washington, DC. He is the CEO and founder of Amen Clinics, with 11 locations nationwide and home to the world's largest brain imaging database for psychiatry with nearly 300,000 SPECT scans on patients from 155 countries. Dr. Amen is a 12 time New York Times bestselling author, including the books Change Your Brain, Change Your Life, Healing ADD, Memory Rescue, Raising Mentally Strong Kids, and The End of Mental Illness. He has published over 90 scientific articles and led groundbreaking brain imaging research on NFL players, childhood trauma, negativity bias, reversing brain aging, obesity and the brain, and predicting treatment responses. With over 10 million followers and multiple PBS specials, his mission is bold: to end mental illness by creating a revolution in brain health. His newest book Change Your Brain, Change Your Pain explores the neuroscience of pain and how to heal it through brain optimization and functional medicine. Host Dave Asprey and Dr. Amen uncover how suppressed emotions, inflammation, gut health, and mitochondrial function all influence pain and what you can do to reverse it using biohacking, functional medicine, and supplements. They explore how chronic pain rewires neural pathways, how to activate your brain's natural calming switch, and why techniques like hypnosis, red light therapy, rage journaling, and havening can restore balance to your nervous system. You'll also learn the surprising links between aspartame, Tylenol, and generational anxiety, and how to protect your mitochondria to optimize energy, metabolism, and emotional resilience. This episode delivers practical, science based tools for brain optimization, sleep optimization, neuroplasticity, and anti aging while connecting the dots between biohacking, psychology, and functional medicine to help you live smarter not harder. You'll Learn: • How emotional pain and physical pain run on the same brain circuits • Why suppressed rage can trigger chronic pain and how to release it • The link between inflammation, gut health, and brain suffering pathways • How supplements like saffron, curcumin, and omega 3s support pain relief and mood • Why red light therapy, hypnosis, and havening boost neuroplasticity and calm the nervous system • How environmental toxins, aspartame, and Tylenol disrupt mitochondria and increase pain • Simple daily habits to retrain your brain for resilience, optimism, and longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: chronic pain neuroscience, emotional pain circuits, Change Your Brain Change Your Pain, Dr. Daniel Amen, Dave Asprey, biohacking, neuroinflammation, anterior cingulate cortex, SPECT imaging, mitochondrial metabolism, functional psychiatry, neuroplasticity, rage therapy, havening technique, red light therapy, saffron supplements, aspartame toxicity, gut brain axis, trauma healing, pain hacking BrainMD Happy Saffron Plus: Affiliate Link: https://www.awin1.com/cread.php?awinmid=89351&awinaffid=855302&ued=https%3A%2F%2Fbrainmd.co…Dave's 15% OFF Discount Code: DAVE15Please note – works on one-time purchases or the first order of a subscription.Thank you to our sponsors! • AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers. • NeuroVeda Health | Go to https://www.neurovedahealth.com/aspery to learn more and book your week. • BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off. • ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Dave's Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated• Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:25 — Dr. Amen's Brain Scan Research 02:11 — Physical vs Emotional Pain 05:15 — Childhood Trauma and Pain 08:10 — The Doom Loop Explained 14:01 — Havening Technique 18:27 — Training Positivity and Hope 22:11 — Rage Therapy and Journaling 26:44 — COVID and Brain Inflammation 29:41 — Mitochondria and Energy 36:14 — Pain Relief Protocol 39:32 — Saffron for Pain 43:28 — Aspartame and Anxiety 47:30 — Pain Switches in the Brain 50:50 — Red Light Therapy 52:39 — Fear and Pain Loops 56:36 — Environmental Toxins58:21 — Final ThoughtsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Rock School
    Rock School - 11/16/25 (AI Contracts)

    Rock School

    Play Episode Listen Later Nov 6, 2025 58:54


    "At least three record companies have extended million dollar contracts to people who create AI music. The US Copyright office has said it will begin extending protection those who use AI as a tool. The PROs will extend licensing. We will tell you what is going on."

    covid-19 christmas music women death live tiktok halloween black ai donald trump english school social rock coronavirus media japan politics dreams young sound song video russia corona ukraine stars elon musk holidays tour guns killers night fake oscars dead lockdown grammy political stage court restaurants ending ufos quit nfts fight series beatles streaming television kansas city panic concerts monsters believing saturday night live joe rogan passing pros moral killed elvis taught presidential logo trigger fund fights naturally conservatives apollo tap died roses grave playlist rockstars rolling burns stones dates finger marijuana phillips simpsons stadiums psychedelics memoir poison lawsuit contracts serial jeopardy bots nirvana backup liberal tariffs managers fat wildfires copyright bugs tours trilogy lsd bus logos inauguration richards petty prom eq boo 2022 johnny cash unplugged mythology motown wrapped rock n roll bug parody deezer commercials halifax ska 2024 jingle strat singers rocketman library of congress alley spears chorus yacht robbers lovin autoimmune slander ramones trademark biscuit mccartney papas ringo moves flute edmund revived graceland defamation cranberries robert johnson trademarks lynyrd skynyrd dire straits spinal leap year live aid torpedos groupies cryptozoology booed spoonful wasserman sesame conservatorship stone temple pilots autotune biz markie moog razzies binaural roadie cbgb jovan midnight special 1980 public broadcasting schoolhouse rock dlr john lee hooker zal busking summer songs libel posthumous idiom bessie smith loggins busker dockery payola pilcher pricilla contentid journeymen 3000 jock jams hipgnosis bizkit rutles zager no nukes journe alone again rock school blind willie mctell metalica vanilli maxs marquee club sherley mitchie soundscan us copyright at40 alago kslu mugwumps
    Learning to Glow: Tips for Women's Health, Optimal Wellness and Aging Gracefully
    147: The Biggest Myths of Losing Weight in Midlife with Yvonne Abdi

    Learning to Glow: Tips for Women's Health, Optimal Wellness and Aging Gracefully

    Play Episode Listen Later Nov 5, 2025 41:56


    Send us a textYvonne specializes in helping women target stubborn belly fat and understand what truly works (and what doesn't) — especially during midlife, when hormones and metabolism start to shift.In this episode, we break down some of the biggest myths about weight loss that women hear every day, and how believing them can actually hold us back from reaching our goals. Yvonne also shares what she's seeing with clients who are taking GLP-1 medications, plus her practical tips on how to eat for long-term success — including protein and fiber sources that make a real difference.We talk about: The most common midlife weight loss myths (and the truth behind them)How hormone changes affect fat storage — especially around the bellyWhat Yvonne recommends for clients using GLP-1 medicationsEasy ways to increase protein and fiber intake dailyFind Yvonne and Links: LINKS:Episode 124 How to Lose Stubborn Belly Fat Click HereYvonne Website Fat Loss Supplements Click HereYvonne Recipe E-Book Click Here Find Jess below!Website: Simply Jess Skincare SIMPLY JESS SKINCARE:Each and every product is naturally derived, highly concentrated and most importantly, super performing! Every product was born out of a need to have a truly pure product that met my high standards for efficacy. Subscribe to Our Newsletter! You can take 20% off Your Order of our all natural skincare line with code: PODCAST Shop Now! Favorite Supplements for Health and Fat loss: Click HERE My favorites are the Power Greens, Digestive Enzymes and Brain Power Mushroom Coffee-15% off with Code: SIMPLYJESSSKINCARE15 Click HereEmail Us! jess@learningtoglow.comFollow us! Instagram Tik Tok

    The Human Upgrade with Dave Asprey
    The New SCIENCE of Energy Healing | Biohacking Updated : 1357

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 4, 2025 37:16


    Your body does not just run on food or supplements. It runs on energy and information. This episode reveals how to harness that energy for faster recovery, stronger mitochondria, and better emotional resilience. You will learn how energy fields, frequency, and information medicine are reshaping the science of human performance, longevity, and anti-aging. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Harry Massey, a British entrepreneur, filmmaker, and visionary in the field of bioenergetics. In his 20s, Harry's health collapsed after a series of physical injuries, viral infections, and emotional trauma left him bedridden for seven years with chronic fatigue syndrome. Conventional medicine could not provide answers, so Harry began studying energy and information as the missing foundations of human health. His discovery of the pioneering research of Australian scientist Peter Fraser led to a breakthrough. Using Fraser's early frequency-imprinted remedies, Harry experienced a dramatic recovery and went on to co-found NES Health, now Energy4Life, to bring this new field of bioenergetics to the world. Backed by published studies at UC San Diego showing a 22 percent increase in mitochondrial efficiency and the activation of more than 1,000 genes for cell resilience, Harry's work unites ancient healing wisdom with modern physics, light therapy, and quantum biology. Together, Dave and Harry explore how bioenergetics, light frequencies, and digital information enhance neuroplasticity, metabolism, and sleep optimization more effectively than supplements or nootropics alone. You will discover how trauma drains energy, how to restore it through the body's natural field communication systems, and how wearable tech and AI are transforming functional medicine. You'll Learn: • How bioenergetic wearables increase mitochondrial energy by 22 percent • Why emotional trauma and energy leaks accelerate aging • How structured water and light frequencies store biological information • The connection between quantum biology, neuroplasticity, and healing • How energy fields regulate longevity, metabolism, and brain optimization • Why AI-powered diagnostics and frequency medicine are the next frontier in biohacking Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: energy healing, bioenergetics, Harry Massey, Dave Asprey, Energy4Life, NES Health, Infoceuticals, GEM wearable, frequency medicine, energy field, quantum biology, mitochondria, neuroplasticity, functional medicine, human performance, longevity, sleep optimization, anti-aging, metabolism, trauma healing, brain optimization, light therapy, structured water, information medicine, UCSD study, Peter Fraser, energy medicine, energy hacking, biohacking, nootropics, supplements, ketosis, fasting, AI, smarter not harder, Danger Coffee **Grab a generous discount from Harry at https://www.e4l.com/Dave. **Thank you to our sponsors! -BiOptimizers | Go to http://bioptimizers.com/dave and use code DAVE15 to get 15% off your order. -AirDoctor | Go to https://airdoctorpro.com/daveasprey and save up to $300 on Air Purifiers. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15• Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Trailer 1:25 – Seven Years Bedridden 3:50 – Three Traumatic Events at 21 6:43 – Searching for Answers 9:02 – Meeting Peter Fraser in LA 11:10 – Dave's Skepticism About Homeopathy 17:42 – The GEM Wearable Device 20:29 – Mitochondrial Efficiency Research 27:05 – Body as Signaling Networks 30:49 – Challenging the Chemical Model 35:10 – Biohacking and Ancient Practices 36:15 – Future of Bioenergetics 44:40 – Closing Thoughts on Energy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    In My Heart with Heather Thomson
    Get Off Your Sugar!

    In My Heart with Heather Thomson

    Play Episode Listen Later Nov 4, 2025 69:33


    Dr. Daryl Gioffre is a renowned longevity and gut microbiome specialist, known for his Acid-Kicking approach to nutrition that empowers clients to combat inflammation and unlock their peak health and energy. Once a self-proclaimed "sugar addict," Dr. Gioffre has transformed himself into a champion of wellness and healer for others. He and Heather talk everything about your Gut, Auto-Immune, Microbiome, Inflammation, the toxicity of Sugar and some practical hacks for treating constipation and other ailments. Dr. Gioffre is committed to reshaping the landscape of nutrition and holistic well-being. As the visionary behind the acclaimed Alkamind and Kick Acid Enterprises brands, he combines his expertise in nutrition and his qualifications as a board-certified chiropractor. He is also a bestselling author of Get Off Your Acid and Get Off Your Sugar: Burn the Fat, Crush Your Cravings, and Go From Stress Eating to Strength Eating. A familiar face on popular television shows such as Live with Kelly and Ryan, Access Hollywood, and Good Day New York, Dr. Gioffre has also been featured in major publications including People Magazine, Vogue, US Weekly, Cosmopolitan, and The New York Post. Dr. Daryl OFFER:  Dr. Daryl is offering great discounts for HHH listeners and viewers as discussed in the episode: His website: ⁠https://www.getoffyouracid.com/pages/about-dr-daryl⁠ Link to the gut testing kits: ⁠https://www.drdaryl.com/labs61812613⁠ use code HEATHER15 for a 15% discount on checkout. Same for ⁠Alkamind products⁠. Use code at checkout HEATHER15 for 15% discount off all products. Website: ⁠www.heatherthomson.com⁠ Social Media:  IG: ⁠https://www.instagram.com/iamheathert/⁠                     You Tube: ⁠https://youtube.com/@iamheathert?si=ZvI9l0bhLfTR-qdo⁠ SPONSOR: BLISSY: Because you're a listener, Blissy is offering 60-nights risk-free PLUS an additional 30% off when you shop at www.Blissy.com/HeatherPod. Your skin and hair will thank you! Learn more about your ad choices. Visit megaphone.fm/adchoices

    Real Science Exchange
    ADSA Winners - 2025

    Real Science Exchange

    Play Episode Listen Later Nov 4, 2025 53:44


    In this episode, we feature some of the winners of poster and oral presentation competitions at the 2025 ADSA Annual Meeting in Louisville, Kentucky. Abstracts can be found here: ADSA 2025 Annual MeetingMS Oral Presentation, ProductionGuests: Trinidad Fernandez-Wallace and Dr. Lautaro Rostoll-Cangiano, University of Wisconsin-MadisonCo-host: Dr. Laura Niehues, BalchemAbstract 1218: Immunity at the crossroads of cellular metabolism: Navigating T helper shifts in the periparturient period of dairy cows. (0:08)Trinidad found that T-helper cell metabolism and proliferation were both upregulated after calving, which may impact the effectiveness of immune responses during the transition period. The group discusses if T-helper cells could be used as a marker of inflammation in the future and how Trinidad's results may have been different if samples had been collected between 3 and 28 days after calving.PhD Oral Presentation, ProductionGuests: Natnicha Taechachokevivat and Dr. Rafael Neves, Purdue UniversityCo-host: Dr. Sion Richards, Balchem Abstract 1107: Relationships between systemic inflammation, subclinical hypocalcemia, and hyperketonemia in clinically healthy Holstein cows. (8:07)Natnicha investigated the association of plasma haptoglobin (an inflammatory marker) on days 1 and 3 in milk with subclinical hypocalcemia and hyperketonemia. Systemic inflammation appears to be associated with subclinical hypocalcemia and hyperketonemia and reduced milk yield in multiparous cows. When multiparous cows exhibited both inflammation and metabolic disease indicators, they produced less milk; however, when primiparous cows exhibited both inflammation and metabolic disease indicators, they produced more milk. 3 Minute ThesisGuests: Savitha Saikumar and Dr. Diwaker Vyas, University of FloridaCo-host: Dr. Laura Niehues, BalchemAbstract 1548: Effects of peripartal supplementation of prototype postbiotics on intake, rumen fermentation, colostrum quality, and performance in transition dairy cows. (15:14)Savitha investigated the effects of a prototype postbiotic supplement in transition cows from 35 days before calving to 63 days after calving. Cows on the postbiotic treatment received 25 grams per day topdressed on their TMR. Before calving, the postbiotic had no effect on dry matter intake, body condition sore, body weight, or total VFAs. After calving, the postbiotic increased dry matter intake and milk yield after 6 weeks, and increased energy-corrected milk and fat-corrected milk with no effect on body weight, body condition score, or rumen fermentation profile.PhD Poster Guest: Amanda Fischer-Tlustos, University of Guelph Abstract 2012: Characterization of dry-period mammary acetate and glucose metabolism and their association with colostrum production in multiparous Holstein cattle. (25:15)Amanda's research evaluated acetate and glucose metabolism in the mammary gland during the dry and calving periods to better understand how colostrum is made. Acetate uptake by the udder remained fairly constant until one week before calving, when it started to increase. Glucose uptake did not increase until the onset of calving. Previous lactation milk production and far-off mammary metabolism were both negatively correlated with colostrum production. Amanda hypothesizes that high producing cows who have trouble drying off may have high amounts of metabolic activity in the mammary gland when they should have low activity, which may result in lower colostrum production at the subsequent calving. PhD Oral Presentation, Southern Branch DivisionGuests: Bridger Sparks and Dr. Clarissa Strieder-Barboza, Texas Tech UniversityCo-host: Dr. Ryan Pralle, BalchemAbstract 1215: Adipose tissue neuro-like cell profile changes with ketosis in dairy cows. (33:05)Bridger investigated neuro-like cells in the adipose tissue of cows with or without subclinical ketosis. The transcriptional profile of neuro-like cells changed when collected from cows with subclinical ketosis, which may indicate a potential regulatory role in adipose tissue metabolism. Perhaps modulation of neuro-like cells could potentially alleviate excessive adipose mobilization in the postpartum period. ADSA Graduate Student Division HighlightsGuests: Evelyn Yufeng Lin, North Carolina State University; Miranda Farricker, Cornell University; Conor McCabe, University of California-Davis; Dr. Maurice Eastridge, Ohio State University. (40:45) Dr. Eastridge is the chair of the ADSA Foundation and explains some of the Foundation's current projects. Evelyn and Conor are past presidents of the ADSA Graduate Student Division, and Miranda is the incoming president. Each student gives a bit of background on themselves and their research and describes what the Graduate Student Division does and how they foster new graduate students in ADSA.  Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

    Physique Development Podcast
    Weighted Vests: Health Hack or All Hype?? (the REAL science) | PD Podcast Ep.242

    Physique Development Podcast

    Play Episode Listen Later Nov 3, 2025 37:24


    If YOU'RE ready to make real, sustainable change in your life, jump on a free call with us - https://physiquedevelopment.typeform.com/to/ToP9TYLEWeighted vests… You've seen them everywhere, but is there any truth to the hype—or is this just another fitness trend that sounds too good to be true? In today's episode, Sue and Alex are cutting through the noise and diving deep into the actual research behind weighted vests. They're breaking down the studies, sharing their personal experiences, and revealing what the science really says about these claims.Sue and Alex discuss why certain populations—especially high-performing women—need to be particularly careful about falling for quick-fix solutions. They'll also share what actually works for improving bone density, preserving muscle mass, and achieving sustainable fat loss.Whether you've been tempted to jump on the weighted vest bandwagon or you're just curious about separating fact from fiction, this episode is a must-listen. Let's get into it!Have questions or comments for the podcast? Drop them here - https://forms.gle/AEu5vMKNLDfmc24M7Check out our FREE 4-Week Glute Program - https://bit.ly/podcastglutesAnd keep the gains rolling with 12 MORE weeks of glute growth (use code POD at checkout for $25 off!) - https://train.physiquedevelopment.com/workout-plans/963551As always, it is our goal not only to supply you, the listener, with valuable insights on the topics or questions but also to plant some seeds for further research and thought. Be sure to like and subscribe and leave us a review wherever you're listening if you loved this episode!Timestamps:(0:00) The weighted vest phenomenon(1:42) Our personal experience(4:36) The claims you've kept seeing(5:13) The research investigation(5:37) Studies being referenced... But misunderstood(7:29) Additional studies showing benefits... But with caveats(9:51) Studies that actually tested walking(14:56) The Peloton context(18:15) The opportunity cost(19:51) Fat loss claims(21:06) The gravitostat hypothesis & human trials(24:53) Tracking accuracy & compensatory behaviors(26:31) What *actually* improves bone density, muscle mass, & fat loss(28:18) Why bone density & muscle mass preservation matters so much(30:40) The reasons high-performing women are especially vulnerable(33:11) The things that *actually* work(35:41) The key takeawayStudies Mentioned:Shaw & Snow (1998) - https://pubmed.ncbi.nlm.nih.gov/9467434Snow et al. (2000) - https://pubmed.ncbi.nlm.nih.gov/10995045Klentrou et al. (2007) - https://pubmed.ncbi.nlm.nih.gov/17724395Jessup et al. (2003) - https://pubmed.ncbi.nlm.nih.gov/12585781Tantiwiboonchai et al. (2011) - https://pubmed.ncbi.nlm.nih.gov/22338922Roghani et al. (2013) - https://pubmed.ncbi.nlm.nih.gov/22441962Beavers et al/ (2025) - https://pubmed.ncbi.nlm.nih.gov/40540267Follow us on Instagram:Coach Alex - https://www.instagram.com/alexbush__Coach Sue - https://www.instagram.com/suegainzPhysique Development - https://www.instagram.com/physiquedevelopment_Physique Development Podcast - https://www.instagram.com/physiquedevelopmentpodcast----Produced by: David Margittai | In Post MediaWebsite: https://www.inpostmedia.comEmail: david@inpostmedia.com© 2025, Physique Development LLC. All rights reserved.

    The Human Upgrade with Dave Asprey
    Your Body Has an Anti-Aging Switch (Here's How to Turn It On) : 1356

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Nov 2, 2025 21:52


    What if getting older had less to do with your birthday and more to do with the health of your cells? Some people in their 50s feel stronger and sharper than ever, while others feel decades older than they are. The difference isn't luck or expensive treatments. In this video, you'll learn what really drives aging, how to measure it, and the surprising practices that can help you feel younger, stronger, and more focused right now.Chapters0:00 – Introduction0:21 – Why aging isn't about time0:49 – Biological age vs chronological age1:40 – Cellular dysfunction and mitochondria3:00 – How weak mitochondria accelerate aging4:00 – Turning on your body's switch6:44 – REHIT workouts to build new mitochondria8:45 – Fueling with fats for clean energy10:05 – Your body's deep clean process13:56 – Fasting methods that support renewal15:58 – The hidden factor: chronic stress19:02 – Stress hacks to unlock longevityConnect with Dave Asprey!Thank you to our sponsor!-MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order.Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Collective: https://www.ourupgradecollective.comUpgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    THE SOVEREIGN SOUL Show: Cutting Edge Topics, Guests & Awakened Truth Bombs with lotsa Love, Levity ’n Liberty.
    The Powerful Untold Story of Haida Gwaii Heroine, Freda Davis, a Rosa Parks of our Time, Saving Mankind

    THE SOVEREIGN SOUL Show: Cutting Edge Topics, Guests & Awakened Truth Bombs with lotsa Love, Levity ’n Liberty.

    Play Episode Listen Later Nov 1, 2025 74:15


    On October 8, 2025, the Alliance of Indigenous Nations (A.I.N.) issued a world's 1st Declaration and Ruling as an Internationally Recognized Tribunal declaring all mRNA COVID-19 vaccines biological and technological gene-editing weapons of mass destruction purposefully designed to eradicate all of humanity from earth.  This declaration was served upon the RCMP and National Defence Headquarters in Ottawa by a man named Chief William Denby, was emailed by our host Brad Wozny to President Trump, Vice President Vance, the Inspector General in Washington, and the magnitude for what was brought forward is thanks to the vigilance and fiery spirit of Freda Davis, a member of the Haida clan in the Pacific Northwest, who did not turn a blind eye to the evil.  She and her husband Elvis Davis, a Chief and also a member of the Haida clan, join our host Brad Wozny to share their gut-wrenching tale of tragedy among this sobering triumph to help save our children and stop the slaughter of mankind.  Listen and Share this powerful story... ⚡️Download & Leverage the Historic A.I.N. Tribunal Declaration with Evidence and Ruling at

    The Human Upgrade with Dave Asprey
    What Happens When You Live Inside a Quantum Field? (Anti-Aging Secrets) : 1355

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Oct 31, 2025 45:24


    Discover how quantum energy, frequency medicine, and consciousness science are rewriting what's possible for human performance and longevity. This episode reveals how your biofield, mitochondria, and brain can be trained, just like your muscles, to achieve higher focus, deeper resilience, and accelerated healing. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Philipp Samor von Holtzendorff-Fehling, founder and CEO of Leela Quantum Tech, about the cutting-edge research proving that quantum energy can neutralize EMF damage, improve neuroplasticity, and activate self-healing at the cellular level. A former telecom executive turned energy researcher, Philipp has led dozens of double-blind, placebo-controlled studies validating measurable shifts in brain waves, ATP production, blood flow, and human coherence. You'll learn how quantum energy interacts with your nervous system, mitochondria, and electromagnetic environment to unlock higher states of consciousness and energy. Philipp and Dave dive into the science behind biofield technology, the real dangers of 5G and EMFs, and how to use frequency devices, structured water, and energetic optimization to enhance your metabolism, sleep quality, and emotional stability. You'll Learn: • How quantum energy measurably enhances brain coherence, ATP production, and longevity • Why EMFs disrupt your mitochondria, and the proven ways to neutralize their effects • How frequency medicine and structured water improve resilience and energy levels • What double-blind studies reveal about human performance, neuroplasticity, and healing • How to integrate quantum tech with fasting, nootropics, and supplements for full-body optimization • The role of consciousness and energy fields in unlocking true anti-aging and human potential This conversation bridges biohacking and functional medicine, exploring how quantum biology complements nootropics, fasting, ketosis, and supplements to accelerate anti-aging and brain optimization. You'll walk away with a new understanding of energy as the missing link in hacking your biology and extending your longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: quantum energy, Leela Quantum Tech, Philipp Samor von Holtzendorff-Fehling, biohacking, EMF protection, frequency medicine, human performance, mitochondria, neuroplasticity, ATP production, brain optimization, anti-aging, functional medicine, structured water, consciousness, energy healing, nootropics, sleep optimization, longevity, quantum biology **Go to https://leelaq.com/dave for a discount on Leela Quantum!**Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Intro 7:04 — Why Quantum is Controversial 10:11 — How Quantum Healing Works 14:47 — EMF Effects on the Brain 17:35 — Living in the EMF Soup 20:55 — Elon Musk and EMF Denial 22:32 — How Leela Quantum Technology Works 26:29 — Water Optimization Research 34:54 — Charging Clothing and Objects 37:31 — Frequency Medicine Applications 42:03 — Skeptics Turned Believers 55:40 — The Energy of Everything (Book Launch) 59:05 — Quantum Upgrade Service Settings 1:02:21 — Protection from Negative Energy See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    The Human Upgrade with Dave Asprey
    Master Stress in 10 Seconds with THIS Heartbeat Technique : 1354

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Oct 30, 2025 70:18


    Heart rate variability isn't just a fitness metric, it's the master signal of human performance, emotional regulation, and longevity. This episode reveals how you can use HRV to hack your nervous system, regulate stress in real time, and build true resilience from the inside out. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Rollin McCraty, Ph.D., Director of Research at the HeartMath Institute and a leading psychophysiologist exploring how the heart, brain and human consciousness are interconnected. For more than three decades his pioneering research into heart-brain communication and geomagnetic field interactions has supported the development of HRV/coherence-training tools and coherence biofeedback technology. His work has been featured in documentaries such as I Am, The Power of the Heart and The Living Matrix. Together, Dave and Dr. McCraty uncover how heart-brain coherence can improve neuroplasticity, optimize sleep, strengthen mitochondria, and create emotional stability even under extreme stress. You'll discover how five minutes a day of coherence training can elevate focus, resilience, and connection, helping every other biohack, from fasting and ketosis to supplements and nootropics, work more effectively. You'll Learn: • What HRV really measures and why it predicts performance and longevity • How coherence breathing balances your nervous system and sharpens cognition • Why emotional regulation begins in the heart, not the mind • How environmental and solar energy affect your physiology, and how to stay stable • The Navy-proven HRV method for better sleep and stress recovery • How coherence training outperforms traditional meditation for daily resilience • The measurable science behind “radiating love” and creating heart-based connection This is essential listening for anyone serious about biohacking, brain optimization, functional medicine, and anti-aging. Whether you're optimizing metabolism, fine-tuning sleep, or upgrading your energy with Danger Coffee, coherence training helps you live smarter, not harder, by syncing your biology with the rhythm of life itself. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: heart rate variability, HRV training, HeartMath, Rollin McCraty, heart-brain coherence, biohacking, emotional regulation, nervous system, stress resilience, neuroplasticity, longevity, sleep optimization, mitochondria, functional medicine, anti-aging, coherence breathing, vagus nerve, HRV recovery, brain optimization Go to https://www.heartmath.com/Dave for 15% off the HeartMath device Thank you to our sponsors! -Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • HeartMath Instagram: https://www.instagram.com/heartmath/ • HeartMath Facebook: https://www.facebook.com/HeartMath • HeartMath TikTok: https://www.tiktok.com/@heartmathinc • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — OG Biohacker 3:21 — What Is Heart Rate Variability? 7:10 — The Four Drummers: Understanding HRV Rhythms 11:50 — Real-Time Training vs Sleep Tracking 18:45 — The Science of Coherence and Consciousness 21:25 — Heart Synchronization in Groups 26:40 — Space Weather and Planetary Rhythms 31:40 — Solar Flares and Human Behavior 38:45 — The Emotional System Runs the Show 49:15 — Getting Started: Training Protocol 57:55 — Advanced Applications: Dating to Performance 1:01:46 — The Frequency Spectrum of Love 1:05:15 — The Heart's Magnetic Field and Congruence See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    The Human Upgrade with Dave Asprey
    Biohacking Cannabis: The DNA Science of Plant Medicine : 1353

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Oct 28, 2025 43:13


    Discover how decoding your DNA can unlock the full potential of plant medicine. This episode delivers a cannabis masterclass for biohackers, revealing how personalized genetics are transforming human performance, brain optimization, and longevity. You'll learn how to identify your ideal cannabis and supplement protocols, balance your endocannabinoid system, and turn precision data into powerful healing. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Len May, MSc, visionary authority in personalized medicine and CEO of EndoDNA, the world leader in DNA-based wellness technology. With over 25 years of pioneering work in genomics, epigenetics, and medicinal cannabis, Len's patented DNA decoding system maps your unique genotypes to design tailor-made health solutions. His company holds the world's largest real-world efficacy database in precision wellness, integrating functional medicine, AI-driven analytics, and genetic data to create personalized blueprints for optimal brain function and performance. Together, Dave and Len explore how your genetic code determines how you respond to cannabis, psychedelics, nootropics, and supplements—and how to use that data to reduce anxiety, improve sleep optimization, and enhance focus. You'll learn how decoding your DNA can guide anti-aging strategies, mitochondrial performance, metabolism, and neuroplasticity, revealing new ways to live longer and smarter. This episode dives deep into the intersection of cannabis science, genomics, and biohacking. You'll discover how genetic polymorphisms influence mood, cognition, and stress response, and how personalized medicine can help you make smarter decisions around ketosis, fasting, and recovery. From optimizing the endocannabinoid system to hacking your biology for resilience and longevity, this is the future of functional medicine in action. You'll Learn: • How the endocannabinoid system regulates mood, focus, pain, and stress response • Which genetic polymorphisms affect cannabis sensitivity, anxiety risk, and dosing windows • How to use DNA testing to select cannabinoid and terpene ratios that fit your biology • Why delivery method matters and when sublingual dosing outperforms inhalation • How personalized cannabis protocols can support sleep optimization, recovery, and emotional regulation • The role of cannabinoids in mitochondrial function, neuroplasticity, and cognitive performance • How pharmacogenomics reduces antidepressant side effects and improves treatment matching • How to screen genetics for safer psychedelic use and avoid adverse reactions • What HLA and related markers reveal about mold sensitivity and inflammation This is essential listening for anyone serious about biohacking, brain optimization, longevity, anti-aging, functional medicine, and living Smarter Not Harder—with precision tools designed to upgrade your mind and body at the genetic level. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: cannabis biohacking, cannabis masterclass, Dave Asprey cannabis, DNA decoding, genetic testing for cannabis, personalized medicine, endocannabinoid system, cannabis genomics, cannabis and DNA, cannabis and genetics, cannabis nootropics, plant medicine biohacking, cannabis brain optimization, cannabis and neuroplasticity, cannabis for focus, cannabis and mitochondria, cannabis metabolism, cannabis for sleep, cannabis anti-aging, precision wellness, functional medicine, cannabis longevity, EndoDNA, Len May, cannabis and AI, biohacking genetics, cannabis and fasting, cannabis and ketosis, personalized supplements, cannabis and mood, cannabis stress response, genetic biohacking, cannabis cognitive performance Thank you to our sponsors! -Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. -Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. -iRestore | Use code DAVE at https://www.irestore.com/ to unlock an exclusive discount on the iRestore Elite. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 – Trailer • 1:25 – Introduction • 7:02 – Cannabis & The Endocannabinoid System • 13:30 – How It Works • 21:38 – Brain Health & Clinical Studies • 26:52 – Psychedelics & Genetic Testing • 31:37 – Genetics vs Epigenetics • 34:53 – Antidepressant Safety • 40:41 – Cannabis Success Stories • 46:02 – ADHD & Personality Genes • 50:54 – Mold, Nicotine & Mitochondria • 55:27 – GLP-1 & Metabolism • 1:00:34 – Microbiome & Medical Freedom See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    The Human Upgrade with Dave Asprey
    This Legal Focus Powder Beats Any Dopamine Detox : 1352

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Oct 26, 2025 18:27


    Dopamine isn't the enemy—low brain energy is. When your mitochondria can't make enough ATP, your neurons misfire, leading to fatigue, brain fog, and lack of focus. In this video, I explain why dopamine problems are really energy problems, how mitochondrial health drives motivation and clarity, and why creatine is one of the most effective and affordable nootropics for restoring mental performance. Learn the biohacks that protect your brain's power plants and keep you sharp all day long.Chapters0:00 – Introduction0:22 – Brain energy vs dopamine0:49 – ATP shortage causes fatigue1:53 – Prefrontal cortex and energy3:08 – Why ATP fuels focus and mood4:40 – Stress, sleep and mitochondria6:00 – Biohacks for energy production7:39 – Backup battery: phosphagen system8:46 – Creatine for brain energy & focus13:18 – Vegans, women and creatine needs15:07 – Best practices for dosing creatine17:53 – Daily creatine + electrolytesThank you to our sponsors!-ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask.Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Danger Coffee: https://dangercoffee.com/DAVE15Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Collective: https://www.ourupgradecollective.comUpgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.