Podcasts about Ige

On this week's episode of Sense by Meg Faure we sit down with renowned Clinical Paediatric Dietitian Kath Megaw for the ultimate baby and toddler feeding masterclass. On this week's episode of Sense by Meg Faure we cover everything from the newborn milk phase right through to the picky toddler years, giving you practical, science-backed answers to the feeding questions that keep parents up at night.Is My Baby Getting Enough? The Newborn Milk PhaseIn those brutal first few weeks, nearly every parent wonders whether their baby is getting enough milk. Kath shares the three objective signs to look for: weight gain, adequate wet nappies, and regular stools. She explains why a crying baby is not a reliable indicator of hunger, and sets out a clear, reassuring weighing schedule for new parents.The Weaning Window: When Is the Right Time?The question of when to start solids is one of the most confusing areas of early parenting. Kath cuts through the noise with a three-part framework: the science (look for supported sitting and neck control, and wait past 17 weeks), your cultural context, and your own gut instinct. She is clear that solids are for teaching and joy, not for fixing sleep, reflux, or poor growth.Gagging vs Choking: What Every Parent Must KnowGagging is loud, active, and protective. Choking is silent, limp, and rare. Kath explains the crucial difference so clearly that parents will never react the same way again. She offers practical guidance for anxious parents and explains why an engaged, calm parent is the single best protection against choking at mealtimes.The Picky Toddler: What Is Normal and What To DoToddler fussiness is developmentally normal. Kath explains why toddlers resist variety, the role of routine and timing in appetite, and why filling gaps with non-nutritious foods can backfire. She also clarifies the milk-to-food balance for toddlers, recommending that milk account for no more than 25% of their total daily nutrition.Myth Busting: Allergen IntroductionKath busts one of the most persistent myths in baby feeding: the three-day wait rule between new foods. Current evidence supports introducing allergen foods as quickly as every 24 to 48 hours. She explains exactly what an IgE reaction looks like and what parents should watch for in the first two hours after introduction.About Our GuestKath Megaw is a Clinical Paediatric Dietitian with over 25 years of experience and the founder of Nutripaeds. She is a consultant to the Parent Sense App and has co-authored six bestselling books including Feeding Sense, Weaning Sense, Allergy Sense, and her most recent release Mindful Meals (2025). She sits on international working groups for neonatal nutrition and the ketogenic diet.Find Kath at nutripaeds.co.za | Instagram: @kath_megaw_paed_dietitian Episode References and Links

Dr. Ruchi Gupta, board-certified pediatrician and founding director of the Center for Food Allergy and Asthma Research (CFAAR), and PA Gary Falcetano joined forces on a Food Allergy Research and Education (FARE) webinar to discuss nuances and insights for managing food allergies across a patient's life. In this episode we share some of the important questions that were asked about specific IgE blood testing, skin testing, component resolved diagnostics, oral food challenges, guideline updates, and common pitfalls. We also explore baked egg and baked milk tolerance, access and affordability barriers, and early peanut introduction in high-risk infants. Clinicians will leave with a clearer framework for interpreting results, selecting the right test, and applying diagnostics to improve management decisions. Resources and references: https://www.thermofisher.com/phadia/us/en/resources/immunocast/managing-food-allergies-across-the-lifespan-diagnostics.html?cid=0ct_3pc_05032024_9SGOV4

You may think of allergies as causing sniffly noses and congestion in the spring or fall. But allergies can go far beyond that. As Dr. Kari Nadeau points out in this episode, allergies can affect us from head to toe, including eyes, nose, throat, lungs, sinuses, skin and gut. In the most dangerous instances, the whole body is threatened with an anaphylactic reaction. That's a medical emergency! One in three Americans will develop allergies at some point in our lives, so it's important to know what works to control them. At The People's Pharmacy, we strive to bring you up to date, rigorously researched insights and conversations about health, medicine, wellness and health policies and health systems. While these conversations intend to offer insight and perspective, the content is provided solely for informational and educational purposes. Please consult your healthcare provider before making any changes to your medical care or treatment. How You Can Listen You could listen through your local public radio station or get the live stream at 7 am EST on Saturday, June 6, 2026, through your computer or smart phone (wunc.org).  Here is a link so you can find which stations carry our broadcast. (Welcome, Huntsville, Alabama!) If you can't listen to the broadcast, you may wish to hear the podcast later. You can subscribe through your favorite podcast provider, download the mp3 using the link at the bottom of the page, or listen to the stream on this post starting on June 8, 2026. What Are Allergies? We begin our discussion of your allergy survival guide with an explanation of what is happening during an allergic reaction. The immune system perceives some foreign compound, usually a protein, as dangerous even though normally it would not be. So it reacts by trying to flush the invader out by producing extra mucus. The turbinate sinuses can make one to two gallons of mucus a day, and naturally, it has to go somewhere. That's why you might be congested. Having all that mucus in the sinuses can also encourage bacterial growth, so if the allergic reaction persists, some people have to deal with sinus infections. Emergency Treatment In determining what works, you need to know the nature of the reaction. If you have two or more organs involved, if you are having trouble breathing or if you feel dizzy, you may be in the midst of an anaphylactic reaction. What works for that is an epinephrine injection and immediate medical attention. This is potentially life-threatening, so you will want to figure out what triggered the reaction so you can avoid it in the future. Once someone has suffered one anaphylactic reaction, they should keep epinephrine with them at all times in case of another episode. Epinephrine comes as a self-injector pen or a nasal spray (neffy). Can You Spot Drug Allergies? In the warnings that are rattled off as part of a TV ad for a pricey new drug, we often hear viewers cautioned not to take the medicine if they are allergic to it. That sounds like simple common sense, but it also has a Catch 22 quality. How do you know you are allergic to a medication unless you take it–and experience an allergic reaction for which you might need treatment. Most of these presumably are immune system-mediated reactions, in which the body produces IgE. That is how allergies to penicillin or sulfa drugs work. Some drugs cause a different type of reaction, not IgE-mediated but dangerous nonetheless. Lisinopril is the most commonly prescribed blood pressure medicine in this country. Like other ACE (ACE is short for angiotensin-converting enzyme) inhibitor medications, lisinopril can trigger angioedema. This swelling can affect the face, lips, tongue and throat, where it can compromise breathing. The most insidious aspect of this reaction is that it can occur after the person has been taking the drug without problems for weeks, months or even years. “Red man syndrome” or infusion reactions in people taking vancomycin can likewise occur without warning. The last type of drug reaction is not actually an allergy at all, although people occasionally use that terminology. It is better described as sensitivity. For example, a stomachache is a common reaction to the antibiotic erythromycin. Some people are disabled by this abdominal pain and try to limit their exposure to erythromycin thereafter. What Works and What Doesn't? Since the immune system is acting inappropriately to cause allergic reactions, treatment should involve immunotherapy. Eye drops can help eyes feel less itchy and irritated. Likewise, OTC nose drops or nasal sprays can often help the nose. The corticosteroid Flonase (fluticasone) and the antihistamine Astepro (azelastine) are good examples. During allergy season, some people find that a daily nasal wash (with a neti pot or NeilMed device) can help reduce the mucus and remove the allergens such as pollen causing the reaction. There are also oral antihistamines and inhalers for asthma. For decades now, allergists have offered their patients shots to help desensitize them to the allergen causing their trouble. Joe had these as a child and teenager and has been largely free of allergies since. Not everyone gets such lasting relief. Complications from Current Therapies Medications have side effects, and that is true of allergy medicines as with other drugs. Antihistamines, especially the older ones like Benadryl (diphenhydramine), are notorious for causing drowsiness. That's one reason it is often included in nighttime pain relievers as the “PM” in drugs like Advil PM. We worry about regular use of such antihistamines because it has been linked to a greater risk for dementia. A second-generation antihistamine such as Allegra (fexofenadine) is much less likely to make someone feel sleepy. However, Dr. Nadeau has seen patients on antihistamines suffer worse allergies if they stop suddenly. The People's Pharmacy has received hundreds of reports from people who experienced unbearable itching upon discontinuing Zyrtec (cetirizine) or Xyzal (levocetirizine). This can last for weeks. Doctors don't usually worry much about steroid nasal sprays like Flonase because they are topical. Presumably, nasal tissues pick up most of the dose. Just the same, using such a nose spray day after day for a long time could result in systemic steroid exposure that is not trivial. Stronger Medicine Dr. Nadeau is enthusiastic about the benefits of two potent prescription medicines. One is Xolair (omalizumab). It was originally developed to prevent asthma, but is now approved for chronic sinusitis, food allergies and chronic hives. Paradoxically, Xolair is one of those medicines that could cause a severe allergic reaction even on the first dose, so the FDA warns that the initial injection should be given in a healthcare setting prepared to treat anaphylaxis. This is uncommon, though, occurring in 0.1 to 0.2% of patients. The other medication Dr. Nadeau is prescribing for allergy patients who don't respond well to other treatments is Dupixent (dupilumab). The FDA has approved this medicine to treat a wide range of conditions, including eczema, asthma, chronic sinusitis, allergic reactions affecting the esophagus and chronic hives, among other things. Most insurance companies will not cover this pricey injection unless the patient has failed all other therapies. Fighting Air Pollution: What Works Air pollution makes allergy symptoms worse, so using an effective air filter inside the home is a good step. A HEPA (high-efficiency particulate-arresting) filter is ideal, especially as part of the air-handling system. If that's not possible, utilizing a MERV 13 in the part of the home where you spend the most time is a good second choice. Sonu One new option for treating allergies is acoustic resonance therapy with the SoundHealth Sonu headband. It uses vibration from sound to loosen mucus from the sinuses so that they can clear. The FDA has approved its use for children as well as adults. New research was just published demonstrating its helpfulness in treating children with nasal congestion (Oto-Open, April-June 2026). SoundHealth has underwritten The People's Pharmacy podcast. Dr. Nadeau has also been compensated for her role in conducting studies of this device (International Forum of Allergy & Rhinology, Dec. 2025). Since it does not employ medications, there are no drug side effects. This Week’s Guest Kari C. Nadeau, M.D., Ph.D., is Dean of the UCLA Fielding School of Public Health ( starting July 1 2026). Until then, she holds many other positions. At Harvard T. H. Chan School of Public Health she is: John Rock Professor of Climate and Population Studies; Chair of the Department of Environmental Health; and Director of the Allergy, Extreme Weather, and Exposomics Lab. Dr. Nadeau is Professor of Medicine at Harvard Medical School and serves in the Division of Allergy and Inflammation at Beth Israel Deaconess Medical Center. She is an Adjunct Professor at Stanford Medical School. Dr. Nadeau is also the co-author of The End of Food Allergy, which provides strategies for treating and preventing food allergies in children. Here is a link to the research underway in her Harvard laboratory. PHOTO CREDIT: STACY GEIKENTaken in April 2017 at Kari Nadeau’s professorship dinner The End of Food Allergy: The Science-Based Plan That Turns Food into Medicine The People's Pharmacy is reader supported. When you buy through links in this post, we may earn a small affiliate commission (at no cost to you). Listen to the Podcast The podcast of this program will be available Monday, June 8, 2026, after broadcast on June 6. You can stream the show from this site and download the podcast for free. This episode has additional information about Nasalcrom (cromolyn sodium nasal spray) and its effect on mast cells; alpha gal allergy to red meat; and the latest thinking on preventing peanut allergy among young children. Download the mp3

On the Evolving Wellness podcast, host Sarah Kleiner interviews returning guest Steve about seasonal allergies, histamine intolerance, and MCAS, emphasizing that the root problem is often loss of immune tolerance driven by gut dysbiosis, leaky gut, and Th1/Th2 imbalance from factors like antibiotics, PPIs, stress, mold, and environmental changes. They contrast symptom tools—antihistamines that block histamine receptors and herbs like quercetin/ginger that stabilize mast cells—with approaches aimed at lowering IgE formation and retraining gut–immune “crosstalk.” Steve describes postbiotics and beta-glucans as “tolerization rehab,” highlighting his product HoloImmune (heat-killed strains) and butyrate (TriButyrin-X) for gut lining and mast cell support, plus DAO enzymes for dietary histamine. They discuss safety, dosing, avoiding live probiotics during flares, and examples including motion sickness, bug-bite welts, and a child's post-viral hives.— GUT HEALTH:  Healthy Gut Supplements- discount automatically applied: Holoimmune: https://healthygut.com/holoimmune-now/?rstr=811&coupon_code=Sarah15 Holozyme Link: https://healthygut.com/holozyme-now/?rstr=811&coupon_code=Sarah15 HCL Guard Link: https://healthygut.com/hcl-guard-now/?rstr=811&coupon_code=Sarah15 Tributyrin X: https://healthygut.com/tributyrin-x-now/?rstr=811&coupon_code=Sarah15 Magnesium: https://healthygut.com/magnesiumhp-now/?rstr=811&coupon_code=Sarah15 _________Sponsored By:→ VivaRays | This episode is sponsored by VivaRays - VivaRays Blue - code YOGI https://vivarays.com/→ Bon Charge | Go to https://boncharge.com/products/demi-red-light-device?rfsn=8108115.26608d & use code SARAHKLEINER for 15% off storewide._________Timestamp:00:00 Coming Up01:02 Podcast Intro Disclaimer02:15 Spring Allergies Setup05:05 Loss Of Tolerance08:02 Why Symptoms Worsen10:25 How Antihistamines Work11:59 Mast Cell Stabilizers14:20 Rewiring With Postbiotics16:20 Red Light Sponsor Break17:59 MCAS Pepcid Bridge22:11 Gut Healing Without Probiotics25:45 Blue Blockers Sponsor Break27:12 Mold And Individual Variance29:57 Antibiotics Farm Effect31:39 Dead Bugs Vs Probiotics32:40 Live vs Dead Probiotics33:25 Immune Software Updates35:28 Strawberry Hives Story36:40 Allergy Medicine Toolkit37:25 DAO Enzyme Explained40:05 Springtime Support Stack40:48 Root Causes and Triggers42:38 Immune Rehab and Tolerance45:56 How to Start Dosing49:11 Coaching Over AI51:47 Antihistamines and Acid Blockers53:56 How Long to Take It56:35 Leaky Gut and Butyrate57:39 Hidden Histamine Symptoms58:29 Motion Sickness and Bug Welts01:00:17 Wrap Up and Resources——— This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________Get all my free guides and product recommendations to get started on your journey!https://www.sarahkleinerwellness.com/all-free-resourcesCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) -  https://www.sarahkleinerwellness.com/coursesMy free product guide with all product recommendations and discount codes:https://www.canva.com/design/DAF7mlgZpJI/xVyE4tiQFEWJmh_Xwx8Kbw/view?utm_content=DAF7mlgZpJIFree Webinar on Light & Health (includes free light bulb guide) - https://www.sarahkleinerwellness.com/mycircadianapp-free-webinarGet Early Access to Podcast Episodes & my Seasonal Food Course + UVB+Red Light Therapy course for free -  https://open.substack.com/pub/sarahkleinerwellness/p/uvbred-light-protocol?r=5eztl9&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

Sponsored by Genentech, a member of the Roche Group, and Novartis Pharmaceuticals Corporation. Intended for US Audiences. This information is for general purposes only and is not a substitute for consulting your healthcare provider about food allergy treatment. Dr. Ari Zelig has been financially compensated by Genentech and Novartis for his participation in this episode. Today, I'm joined by Dr. Ari Zelig, a board-certified allergist and immunologist to unpack what's really happening when it comes to food allergies - and why so many more people are dealing with them today. If you are navigating food allergies, or if you've ever wondered if what you're experiencing might be more than just a sensitivity, this episode features an informative discussion on these topics! In this episode, we dive into the reality of living with food allergies, from the day-to-day challenges that families carry to the misconceptions that still exist around what an allergic reaction to food actually looks like. Dr. Zelig breaks down IgE-mediated food allergies, what's happening in the body during a reaction, and why early exposure guidelines for kids have changed. Plus, we discuss a treatment option, XOLAIR (omalizumab), an FDA-approved prescription medication for subcutaneous use that can help reduce allergic reactions to multiple foods that may occur after accidental exposure in people with IgE-mediated food allergies one year of age and up. While taking XOLAIR you should continue to avoid all foods to which you are allergic. If you or a loved one has been diagnosed with food allergies, talk to your allergist and ask about XOLAIR. You can also find more information at XOLAIR.com. XOLAIR is one of several available treatment options for IgE-mediated food allergy and it may not be appropriate for all patients. What is XOLAIR?XOLAIR®(omalizumab) for subcutaneous use is an injectable prescription medicine used to treat food allergy in people 1 year of age and older to reduce allergic reactions that may occur after accidentally eating one or more foods to which you are allergic. While taking XOLAIR you should continue to avoid all foods to which you are allergic. It is not known if XOLAIR is safe and effective in people with food allergy under 1 year of age. XOLAIR should not be used for the emergency treatment of any allergic reactions, including anaphylaxis. What is the most important information I should know about XOLAIR?Severe allergic reaction. A severe allergic reaction called anaphylaxis can happen when you receive XOLAIR. The reaction can occur after the first dose, or after many doses. It may also occur right after a XOLAIR injection or days later. Anaphylaxis is a life-threatening condition and can lead to death. Go to the nearest emergency room right away if you have any of these symptoms of an allergic reaction:· wheezing, shortness of breath, cough, chest tightness, or trouble breathing· low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of “impending doom”· flushing, itching, hives, or feeling warm· swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing Your healthcare provider will monitor you closely for symptoms of an allergic reaction while you are receiving XOLAIR and for a period of time after treatment is initiated. Your healthcare provider should talk to you about getting medical treatment if you have symptoms of an allergic reaction. Please listen to the Important Safety Information throughout and stay tuned for additional safety information at the end of this podcast. See full Prescribing Information, including Medication Guide, at bit.ly/XOLPI. This episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct, or indirect financial interest in products, or services referred to in this episode. Produced by Dear Media M-US-00032583(v1.0) 5/26See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, host Marcella Feathers and Dr. Nicholas Cline examine mail-in allergy tests that use hair or saliva, explaining why experts warn they're unreliable: they're often unvalidated, may measure IgG (not the allergy-linked IgE), produce confusing false positives or negatives, and can be costly. Learn why certain methods of allergy testing are preferred by the specialty and why consulting an allergist before avoiding foods or purchasing an at-home kit can save you money and keep you safe!

In this episode of The Cutaneous Connection, Dermatology Times revisits a recent video episode of the Derm Dispatch show where host Renata Block, DMSc, MMS, PA-C, sits down with Zachary Rubin, MD — allergist, pediatrician, and New York Times bestselling author of All About Allergies — to explore the intersection of dermatology and allergy. Together, they tackle one of the most persistent myths in practice: that food elimination can treat atopic dermatitis. Dr. Rubin breaks down the difference between IgE-mediated allergic reactions and the complex inflammatory nature of eczema, explains the atopic march, and discusses how understanding the gut-lung-skin axis can empower patients to take charge of their care. The conversation also covers the latest treatment advances — from JAK inhibitors to novel biologics — and touches on indolent systemic mastocytosis and the truth about so-called hypoallergenic dogs. A must-listen for any clinician treating allergic and inflammatory skin disease.For more content, visit https://www.dermatologytimes.com/

Thyroid Symptoms, Normal Labs, and Root Causes: Dr. Kevin Smith on Hashimoto's, Functional Medicine, and Chronic Conditions | Conversations with a Chiropractor Episode Description In this episode of Conversations with a Chiropractor, Dr. Stephanie Wautier sits down with Dr. Kevin Smith, a functional medicine practitioner and founder of the Chronic Conditions Center in Pittsburgh, Pennsylvania. Dr. Smith specializes in helping people better understand the root causes behind chronic health problems, including thyroid dysfunction, gut issues, autoimmunity, chronic pain, inflammation, peripheral neuropathy, insulin resistance, and other complex conditions. This conversation focuses heavily on thyroid health, especially the frustration many people feel when they have symptoms of hypothyroidism, but are told their labs are "normal." Dr. Smith explains why thyroid symptoms can involve far more than a simple TSH reading, and why many cases of hypothyroidism may be connected to Hashimoto's disease, an autoimmune condition that affects the thyroid. Stephanie and Dr. Smith talk through common thyroid symptoms, including fatigue, hair loss, weak nails, digestive changes, sleep issues, brain fog, mood changes, infertility, and skin problems. They also discuss why a deeper look at the body may include the immune system, gut health, liver function, blood sugar, cortisol, sex hormones, inflammation, food sensitivities, unresolved infections, and nutrient status. The episode also explores the difference between managing symptoms and looking for the underlying reasons a person may not feel well. Dr. Smith shares how he uses detailed intake forms, comprehensive lab testing, metabolic questionnaires, food sensitivity testing, lifestyle changes, nutrition, supplements, and retesting to help patients better understand what is happening in their body. This conversation is educational and is not a replacement for personal medical care. If you are dealing with thyroid symptoms, autoimmune concerns, medication questions, or chronic health issues, work with a qualified healthcare provider who can evaluate your individual situation. In This Episode, Discover Common symptoms of hypothyroidism and low thyroid function Why "normal labs" may not tell the whole story The connection between Hashimoto's disease and thyroid dysfunction Why Dr. Smith describes many thyroid issues as immune system issues How the brain, pituitary gland, thyroid, liver, gut, and carrier proteins all play a role in thyroid function Why every cell in the body depends on thyroid hormone for energy regulation How chronic inflammation, blood sugar issues, cortisol, sex hormones, food sensitivities, and infections may affect thyroid physiology Why comprehensive lab testing may reveal patterns missed by basic panels The difference between food allergy testing and food sensitivity testing How lifestyle changes, nutrition, supplements, and retesting fit into functional medicine care Why patients may need to take a more active role in understanding their health Stay Connected & Explore Learn More About Dr. Kevin Smith & Metabolic Solutions: Dr. Kevin Smith / Metabolic Solutions: https://www.metabolicsolutions.net/ Free 2-Minute Metabolic Health Assessment: https://www.metabolicsolutions.net/metabolic-scorecard/ Chronic Conditions Center: https://www.chronicpa.com/ Connect with Conversations with a Chiropractor: Follow Us on YouTube: http://www.youtube.com/@ConversationswithaChiro Follow Dr. Stephanie on Facebook: https://www.facebook.com/wautierwellness Email for show-related inquiries and sponsorships: drstephaniewautier@yahoo.com Want to be a guest on Conversations with a Chiropractor? Send Stephanie Wautier a message on PodMatch, here: https://www.podmatch.com/hostdetailpreview/drstephanie Credits Podcast production by Brand|Sound. Start your podcast journey by emailing brandsoundpodcasts@gmail.com. Chapters 00:00 Introduction to Conversations with a Chiropractor 00:56 Meet Dr. Kevin Smith 01:55 Why Thyroid Health Is the Focus 02:15 Common Symptoms of Hypothyroidism 04:01 When Symptoms Persist but Labs Look Normal 05:13 Looking Beyond Basic Thyroid Testing 05:47 Hashimoto's Disease and Autoimmunity 07:15 Why the Immune System Matters in Thyroid Health 08:25 Thyroid Medication, Unresolved Symptoms, and the Bigger Pathway 09:04 The Brain, Pituitary Gland, TSH, T3, and T4 10:37 The Thyroid as the Body's Energy Regulator 11:48 Brain Fog, Mood, Gut Symptoms, and Cellular Energy 13:16 Triggers That Can Disrupt Thyroid Physiology 15:13 Hypothyroidism vs. Hyperthyroidism 16:14 Intake Forms, Questionnaires, and Foundational Labs 18:14 What Dr. Smith Looks for in Lab Work 19:53 Insurance, Coverage, and the Limits of Symptom Management 22:29 Managing Symptoms vs. Looking for Root Causes 23:30 Patients Who Feel Like They Are Out of Options 25:24 Medication Side Effects and Patient Education 27:26 Dr. Google, Food Testing, and Objective Data 29:36 IgG, IgE, and Food Sensitivity Testing 31:48 Delayed Reactions and the Long-Fuse Firecracker Analogy 34:43 Celiac Disease, Crohn's, Colitis, and Autoimmune Patterns 35:48 Treatment Through Lifestyle, Nutrition, and Supplements 37:51 Affordability, Priorities, and Investing in Health 40:23 Owning Your Health and Understanding the Problem 43:26 Chiropractic, Functional Medicine, and Knowing the Right Tool 45:11 How to Find Dr. Kevin Smith 46:26 Working With Patients Outside Pennsylvania 47:34 Final Thoughts and Closing

Transcript [Music] From Washington State University Extension, this is Food Safety in a Minute. A food allergy happens when your immune system mistakes certain food proteins as threats and makes IgE antibodies; eating that food again can trigger a reaction. Reactions often start within minutes to two hours and can range from hives or stomach upset to life threatening anaphylaxis. In the United States, the “Big 9” allergens are milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, and sesame. To help you avoid them, FDA requires ingredient lists and clear naming of major allergens on packaged foods, while USDA FSIS enforces similar declarations on meat, poultry, and certain egg products. Always read labels, ask questions when dining out, and carry epinephrine if prescribed by your doctor. I'm Susie Craig for Food Safety in a Minute. [Music] Resources United States Department of Agriculture Food Safety Inspection Service. Food Allergies: The “Big 9”. https://www.fsis.usda.gov/food-safety/safe-food-handling-and-preparation/food-safety-basics/food-allergies-big-9. Accessed online 3/2/26.

It's one of the most common—and most frustrating—complaints in the Emergency Department: the patient covered head-to-toe in hives, miserable, itching, and desperate for relief. In this episode of EM Pulse, we welcome back ED Clinical Pharmacist Haley Burhans to tackle the “uncomfortable” topic of urticaria. We move past the myths of one-and-done doses and explore why your standard allergy dosing might be leaving your patients itching for more. The Power of Second-Generation Antihistamines Haley explains why second-generation antihistamines (cetirizine, levocetirizine, fexofenadine) should be your first-line ED therapy, rather than the old school standard, diphenhydramine (Benadryl). Xyzal vs. Zyrtec: We break down the L-enantiomer (levocetirizine) and whether it actually beats its predecessor in preventing drowsiness. The “Double Dose” Pearl: For acute urticaria in the ED, 10mg of cetirizine isn’t enough. Haley recommends starting with 20mg for adults (or doubling the weight-based dose for kids) to see relief within 20–60 minutes. The 4x Rule: Guidelines now support up to four times the standard daily dose for refractory cases (usually split BID). We discuss the safety data behind these higher regimens and why they are tolerated so well. The Steroid Trap and the Rebound Effect Patients often come in requesting steroids but they are NOT the primary cure for urticaria. The Antihistamine Backbone: Steroids treat inflammation, but the antihistamine treats the underlying stimulus. If a patient stops their antihistamines and only takes a steroid burst, they are set up for a miserable rebound. Dosing Strategies: If you do use steroids, keep it to a burst or taper of 10 days or less. We discuss the utility of methylprednisolone (Medrol Dosepak) versus a simple prednisone burst/taper or a course of longer-acting dexamethasone. Beyond the Basics: Benadryl and the MABs The Danger of “Dirty” Drugs: Why diphenhydramine has fallen out of favor due to its sodium channel blocking side effects, anticholinergic toxicity, and psychiatric risks. The Future of Itch: A look at emerging biologics like omalizumab. While these IgE-blockers shouldn't be started in the ED, it's important to know about them to treat patients who are taking them, or who present with rebound urticaria after recently stopping them. Key Takeaways Go Big on Second Generation Antihistamines: Start with a double dose of cetirizine in the ED. It's safe, effective, and less sedating than first-generation alternatives. Discharge patients on that double dose twice a day. Think Long-Term: Urticaria pathways need time to “cool down.” Advise patients to stay on the prescribed meds/doses for 1–2 months, not 1–2 days. Steroids are Adjuncts: Use a short burst (

Anaphylaxis explained including anaphylaxis pathophysiology (immunologic vs non immunologic), clinical features, diagnosis, and treatment. Includes recognition of airway compromise, use of intramuscular adrenaline (epinephrine), biphasic anaphylaxis, refractory anaphylaxis, and the immunology underlying type 1 hypersensitivity reactions. PDFs available at: https://rhesusmedicine.com/pages/topicsConsider subscribing (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Patreon: https://www.patreon.com/rhesusmedicineBuy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 What is Anaphylaxis?0:32 Anaphylaxis Pathophysiology4:08 Anaphylaxis Causes5:28 Anaphylaxis Symptoms7:44 Anaphylaxis Diagnosis8:32 Anaphylaxis TreatmentLINK TO MNEMONICS:https://www.youtube.com/watch?v=p-XE7PiwGgE&list=PLGNSE_HvIV4t7a33bbHN1fq-j_tge0GmpLINK TO SOCIAL MEDIA: https://www.instagram.com/rhesusmedicine/ReferencesBMJ Best Practice (2025) Anaphylaxis – Symptoms, diagnosis and treatment. Available at: https://bestpractice.bmj.com/topics/en-gb/501British Society for Immunology (2021) Anaphylaxis. Available at: https://www.immunology.org/public-information/bitesized-immunology/immune-dysfunction/anaphylaxisRCEMLearning (2023) Anaphylaxis. Available at: https://www.rcemlearning.co.uk/reference/anaphylaxis/Simons, F.E.R., Ardusso, L.R.F., Bilo, M.B., El-Gamal, Y.M., Ledford, D.K., Ring, J., Sanchez-Borges, M., Senna, G.E., Sheikh, A. and Thong, B.Y. (2018) World Allergy Organization anaphylaxis guidance 2018. Journal of Allergy and Clinical Immunology, 141(2), pp. 419–420.e1. Available at: https://www.jacionline.org/article/S0091-6749(18)30571-2/fulltextTurner, P.J., Worm, M., Ansotegui, I.J. and El-Gamal, Y.M. (2024) IgE and non-IgE-mediated pathways in anaphylaxis. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC12350582/Cardona, V., Ansotegui, I.J., Ebisawa, M., El-Gamal, Y., Fernandez Rivas, M., Fineman, S., Geller, M., Gonzalez-Estrada, A., Greenberger, P.A., Sanchez Borges, M., Senna, G., Sheikh, A. and Tanno, L.K. (2020) ‘World allergy organization anaphylaxis guidance 2020', World Allergy Organization Journal, 13(10), p. 100472. doi:10.1016/j.waojou.2020.100472.Please remember this podcast and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice. 

Asthma affects over 26 million people in the U.S., yet outcomes can vary dramatically based on factors beyond disease severity. This episode explores the critical gap between diagnosis and optimal asthma control, focusing on how socioeconomic status, access to care, and environmental exposures shape patient outcomes. Through a mock case study, we examine disparities in healthcare access, allergist availability, and treatment adherence, alongside key topics such as epidemiology, risk stratification, environmental trigger identification, diagnostic testing and interpretation, and guideline-based management. The discussion highlights the role of allergic sensitization in asthma pathophysiology and emphasizes the importance of comprehensive specific IgE testing in identifying root causes. Clinicians will gain actionable strategies to improve diagnosis, implement cost-effective interventions, and optimize asthma management directly within primary care settings. Resources and references: https://www.thermofisher.com/phadia/us/en/resources/immunocast/asthma-management-disparities-ige-testing-primary-care.html?cid=0ct_3pc_05032024_9SGOV4

This week, Zoë mailed a chunk of her hair to a stranger in Florida. For science. For journalism. For your benefit, really. The $60 hair sample test came back flagging her as "highly reactive" to 210 foods, including emu, ostrich egg, hot dog, and ground horse meat. Reader, she has not eaten ground horse meat in over a decade.The food sensitivity industry is a multi-billion-dollar grift built on real symptoms and fake frameworks. We trace it from 1906, when allergy was first defined as a real clinical thing, through the 1950s clinical ecology movement, through cytotoxic testing, IgG panels, electrodermal screening, and bio-resonance, and finally to the at-home hair test in your DMs. It's the same idea in different packaging every decade. Like a body-snatcher, but for grift. (We use a lot of John Carpenter references in this one.)Then Kylee walks through what the science actually says: the difference between IgE allergies, IgG sensitivities, and intolerances. What real diagnostic testing looks like (skin prick tests, blood panels, hydrogen breath tests, structured elimination diets with a professional). Why hair testing, IgG panels, and bio-resonance devices have no validated diagnostic mechanism. And why these tests disproportionately target women, who are statistically more likely to feel dismissed by their doctors and more likely to seek answers in the wellness market.We also get into why endurance athletes are uniquely vulnerable to this stuff. When your gut acts up during training, the wellness industry hands you a list of 210 foods to eliminate. Your sports dietitian hands you a fueling plan. Guess which one tends to lead to a stress fracture.The bottom line: your symptoms deserve a real answer. Don't let a hair test substitute for actual care.This episode is supported by:rabbit — Use code YOURDIETSUCKS10 for 10% off at runinrabbit.com Their trail line is genuinely the only running gear we actively look forward to wearing.Tailwind Nutrition — Use code YOURDIET20 for 20% off at tailwindnutrition.com. Endurance fuel that doesn't taste like a chemistry set. Try the Mandarin Orange or the Daily Hydration Strawberry Lemonade.Osmia Skincare — Use code YDS20 for 20% off at osmiaskincare.com. Clean, science-forward skincare from a real-deal physician-founder. The Himalayan Salt Scrub and Lavender Body Mousse are the post-long-run reset.Microcosm Coaching — Endurance coaching from people who know what they're doing. Free consultations at microcosm-coaching.com.Website: yourdietsuckspodcast.com — full episode pages, references, transcripts, and the blog.Patreon: patreon.com/YourDietSucks — bonus episodes, monthly Q&As with Kylee, and the community thread. $3/month keeps us independent and ad-manager-free.Merch: teepublic.com/user/your-diet-sucks — TeePublic shop. (Heads up: free Patreon members can win a YDS shirt by joining a paid tier between now and May 31. Drawing June 1.)If this episode helped, send it to a friend who's been thinking about mailing their hair somewhere. Word of mouth is how this show grows.SPONSORSMORE YDS

Alpha-gal syndrome is an emerging and often underrecognized allergy triggered by a tick bite that can cause delayed reactions to red meat and mammalian-derived products. In this episode, host Stacy Lauderdale is joined by clinical experts Zack Stacy and Kyna Henrici to unpack the science behind alpha-gal, its implications in healthcare settings, and the operational challenges providers face in managing this complex condition.    Guest Speakers:   Zachary Stacy, Pharm.D., MS, FCCP, BCPS  Clinical Pharmacy Specialist, Surgery  BJC Health   Kyna Henrici, RN  Medical Evidence Director - Cardiovascular  Vizient, Inc.    Host:    Stacy Lauderdale, Pharm.D., BCPS  AVP, Evidence-Based Medicine  Vizient, Inc.    00:05 – Introduction  Podcast introduction and welcome to VerifiedRx  00:14 – What is alpha-gal syndrome  Overview of alpha-gal syndrome  Delayed allergic reactions after eating red meat  Often linked to tick bites  00:48 – Meet the Guests   Zack Stacy, clinical pharmacy specialist  Kyna Henrici, medical evidence director  01:10 – Understanding the Allergy  Alpha-gal is a carbohydrate in nonprimate mammals that can trigger an allergy in humans  Key difference is delayed reaction timing  Symptoms are not always easy to trace   01:32 – How It Develops  Triggered by tick bites  Immune system produces IgE antibodies   Oral exposure to alpha-gal leads to delayed reactions  IV exposure to alpha-gal can cause immediate reactions  02:17 – Prevalence and Diagnosis Challenges  More common in Midwest and southern United States  Likely underdiagnosed  Often mistaken for general food allergies  Allergy may fade over time  03:07 – Risks in Healthcare Settings  Patient safety concerns beyond food  Mammalian components in medications and devices  Examples include heparin and surgical materials  03:44 – Hidden Medication Risks  Inactive ingredients can be animal derived  Examples include glycerin, lactose, amino acids, stearates  Difficult to identify and track  04:42 – Lack of Transparency  No centralized ingredient database  Sourcing can change frequently  Variability across manufacturers and batches  05:33 – Screening in Surgical Settings  Medication review at NDC level  Identification of active and inactive ingredients  May require contacting manufacturers  06:45 – Timing Challenges  Urgent procedures limit investigation time  Manufacturer responses may take days  Alternative medications often needed  07:14 – Identifying At Risk Patients  Many patients are unaware they have alpha-gal syndrome  Screening includes questions about dairy tolerance  Three patient categories used for evaluation  08:32 – Using Dairy as a Screening Tool   Dairy tolerance helps guide risk level  Food exposure typically higher than medication exposure  Determines need for deeper review  09:12 – Managing Emergencies  Focus shifts from avoidance to risk mitigation  Use of team communication and clear documentation  Preparation for unavoidable exposure  10:03 – Prevention and Preparedness  Stock alpha-gal safe medications when possible  Prepare for allergic reactions with standard treatments  10:47 – Team Based Care Approach  Collaboration across care teams is essential  Premedication strategies may be used  Close monitoring for reactions  11:11 – Gaps in Care  Limited visibility into product ingredients  Need for better labeling and transparency  11:33 – Need for Standardization  Call for clearer guidance and clinician education  Desire for centralized resource for medication ingredients  12:24 – Monitoring Challenges  CDC tracking decreased after privatization of testing  Cases likely still increasing  12:53 – Closing Remarks    Links and Resources: Alpha-gal Syndrome | Alpha-gal Syndrome | CDC    Subscribe Today!  Apple Podcasts  Spotify  YouTube  RSS Feed   

Support the Institute today. https://givenow.nova.edu/the-institute-for-neuro-immune-medicine-inim-2025 In today's episode, Haylie Pomroy is joined by Dr. Andrew Campbell, a specialist in complex chronic illness, toxic exposures, and immune dysfunction. Together, they examine the clinical science behind mycotoxin illness — how mold-derived toxins enter the body, why they are frequently missed or misdiagnosed, and how they may be driving some of the most prevalent and poorly understood chronic conditions of our time. Dr. Campbell shares the evidence base connecting mycotoxins to neurological diseases including multiple sclerosis, Alzheimer's, ALS, and Parkinson's disease, as well as autoimmune disorders, chronic fatigue syndrome, fibromyalgia, autism, and reproductive health conditions. He explains the critical difference between urine and serum mycotoxin testing, clarifies what IgG and IgE antibodies actually indicate about current versus past exposure, and outlines a clinically validated approach to diagnosis and treatment through My Myco Lab. He also addresses environmental sources of mycotoxin exposure, the first rule of toxicology in clinical practice, and why accurate testing is the foundation of any meaningful recovery pathway. Dr. Andrew Campbell is a Medical Clinician, Director, Officer, Advisor, and Medical Consultant, also Editor-in-Chief of several journals and research studies, and was recently selected as Top Medical Consultant of the Year for 2020 by the International Association of Top Professionals (IAOTP) for his outstanding leadership, dedication, and commitment to the healthcare profession. With over 45 years of professional experience as a renowned Medical Clinician, Dr. Campbell has certainly proven himself as an expert in the field of integrative health and traditional medicine. Dr. Campbell is a dynamic, results-driven leader who has demonstrated success by treating the most complex patients and having extensive experience with testing for molds and mycotoxins from environmental and toxic exposures. He is fluent in Arabic, Hungarian, French, Spanish and English. He has also effectively worked alongside medical professionals from other cultures in Central and South America, Western and Eastern Europe, and the Middle East.   Website: https://andrewcampbellmd.com/  LinkedIn: https://www.linkedin.com/in/andrewwcampbell-md/  YouTube: https://www.youtube.com/c/MyMycoLabLLC    Learn more about MyMycoLab: https://mymycolab.com/    Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.   Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com   Instagram: https://www.instagram.com/hayliepomroy  Facebook: https://www.facebook.com/hayliepomroy  YouTube: https://www.youtube.com/@hayliepomroy/videos  LinkedIn: https://www.linkedin.com/in/hayliepomroy/  X: https://x.com/hayliepomroy    Enjoy our show? Please leave us a 5-star review on the following platforms so we can bring hope and help to others.   Apple Podcasts: https://podcasts.apple.com/us/podcast/hope-and-help-for-fatigue-chronic-illness/id1724900423   Spotify: https://open.spotify.com/show/154isuc02GnkPEPlWfdXMT   Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d    This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here.   Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM

Hva er egentlig “hjernetåke” – og hvorfor opplever så mange i dag å være slitne, ukonsentrerte og ute av balanse? Kan det vi spiser påvirke mer enn vi tror – ikke bare fordøyelsen, men også hjernen, energinivået og hvordan vi fungerer i hverdagen?I denne episoden har jeg med meg lege, forfatter og en av Norges mest profilerte stemmer innen kosthold og helse, Sofie Hexeberg. Sammen med sin mann Erik Hexeberg driver hun Dr. Hexebergs klinikk i Tønsberg og Bærum, og hun har i en årrekke arbeidet med hvordan mat påvirker sykdom og helse. Hun er også medforfatter av flere bestselgende bøker, blant annet Ut av hjernetåken, Nytt blikk på kolesterol og Nytt blikk på autoimmun sykdom.I denne samtalen utforsker vi hva hjernetåke er, hvorfor det kan oppstå, og hvordan kosthold, tarmhelse og individuelle forskjeller kan spille en rolle. Vi snakker også om matintoleranser, “lekk tarm” og MUPS.I episoden lærer du mer om:Hva hjernetåke er, og hvilke symptomer som ofte går igjenMulige årsaker, inkludert kosthold, tarmhelse og livsstilHva vi vet (og ikke vet) om lekk tarm og matintoleranserForskjellen på IgG, IgA og IgE-tester – og hvordan de kan tolkesHvorfor noen opplever bedring ved å endre kostholdSammenhengen mellom MUPS og kostholdOm vi alle bør spise likt – eller om vi er mer ulike enn vi trorHva forskningen sier om lavkarbo og ketogent kostholdHvordan du kan begynne å utforske hva som fungerer for degSofie deler også egne erfaringer som lege, hva hun selv gjør for egen helse, og hvordan man kan navigere i et felt preget av både sterke meninger og ulike perspektiver.Kontakt Sofie Hexeberg:Hjemmeside: www.drhexeberg.noBok: Ut av hjernetåken Tusen takk til ukens sponsor Csoaps! Du får nå 20 prosent rabatt på nettbutikken ved å bruke rabatt koden legeromlivet20 på csoaps.comAlt godt,AnnetteFølg meg gjerne på:instagramNyhetsbrev: annettedragland.noFå bonusepisoder og støtt podcasten på https://podcasts.apple.com/no/podcast/leger-om-livet/id1539212619 Disclaimer: Innholdet i podcasten og på nettsiden er ikke ment å utgjøre eller erstatte profesjonell medisinsk rådgivning, diagnose eller behandling. Søk alltid råd fra legen din eller annet kvalifisert helsepersonell hvis du har spørsmål angående en medisinsk tilstand. Hosted on Acast. See acast.com/privacy for more information.

RNA microbiome testing reveals what DNA gut tests fundamentally miss. Your gut bacteria have 3,000+ genes each — DNA tests see zero of their actual activity. Dr. Momchilo (Momo) Vuyisich, Co-founder & CSO of Viome and former Los Alamos National Laboratory scientist, explains why RNA-based metatranscriptomics is a quantum leap over DNA sequencing for understanding your microbiome and personalizing nutrition. Meet our guest Dr. Momo Vuyisich spent 12 years at Los Alamos National Laboratory developing RNA-based technology for digitizing human biology. He co-founded Viome in 2016 with Naveen Jain, and the platform has since tested 500,000+ customers across 100+ countries. His personal journey with NEU5GC autoimmune sensitivity drove his mission to replace opinion-based nutrition with data-driven, personalized recommendations. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways DNA microbiome tests show composition only — RNA tests reveal which of 3,000+ bacterial genes are actually active 16S rRNA sequencing cannot distinguish pathogenic bacteria from beneficial ones Akkermansia can protect or destroy your gut lining depending on fiber intake and gene expression Carnitine supplements may cause cardiovascular disease via the TMAO pathway in certain people Viome's biological aging clock shows keto and paleo dieters age faster on average No whole food is universally good or bad — personalization requires your own molecular data The gut microbiome stays stable for 5-6 months; test semi-annually Viome currently measures 25,000 of ~100,000 biochemical reactions powering the body Three randomized controlled trials validate Viome's personalized nutrition approach   Episode highlights 00:00 Introduction 02:44 Why RNA is the single best molecule to study 06:16 RNA instability — why it took 6 years to develop 08:02 Why 16S sequencing is nearly useless 11:02 Akkermansia's 3,000 genes: help or harm? 17:37 Microbiome as a dynamic self-adjusting ecosystem 23:20 NEU5GC sensitivity & mammalian food reactions 25:50 Food sensitivities (IgG) vs allergies (IgE) 29:55 Viome's 3-part approach: seal gut, reduce inflammation, personalize 41:07 Biological aging clock: keto & paleo age faster 49:13 Dry fasting crashed mitochondrial function score 52:07 Machine learning identifies metabolic bottlenecks 1:00:23 Viome measures 25% of human biology, 10% actionable   Links Watch it on YouTube: https://youtu.be/bB8Zj_9pIv8  Full episode show notes: https://outliyr.com/257  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

This episode examines the spectrum of food allergy, from IgE-mediated disease to food protein induced enterocolitis syndrome and eosinophilic conditions, and explores how diet, skin barrier function, and the microbiome interact in early life. Timestamps: 00:53 – Spectrum of allergic diseases 05:00 – Nutrition and immune activation 07:22 – Atopic dermatitis 08:55 – IgE-mediated food allergy 10:28 – Future management pathways

La inteligencia artificial está transformando la medicina. En este episodio exploramos cómo funciona la inteligencia artificial en el campo médico, qué problemas puede ayudar a resolver y cuáles son los desafíos éticos y científicos que aún enfrenta. ¿Puede una máquina diagnosticar enfermedades con mayor precisión que un médico? ¿Cómo está cambiando la inteligencia artificial la práctica médica actual y qué implicaciones tiene para el futuro de la saludReferencias- Ávila-Tomás, J. F., Mayer-Pujadas, M. A., Quesada-Varela, V. J. (2020). Artificial intelligence and its applications in medicine II: Current importance and practical applications. Atem primaria 53: 81-88 https://doi.org/10.1016/j.aprim.2020.04.014- Couzin-Frankel, J. (2019). Medicine contends with how to use artificial intelligence. Science. https://doi.org/10.1126/science.364.6446.1119- de Vries, C. F., Lip, G., Staff, R. T., et al. (2026). Prospective evaluation of artificial intelligence integration into breast cancer screening in multiple workflow settings: The GEMINI study. Nature Cancer, 7, 484–493. https://doi.org/10.1038/s43018-026-01126-1- Jumper, J., Evans, R., Pritzel, A., et al. (2021). Highly accurate protein structure prediction with AlphaFold. Nature, 596, 583–589. https://doi.org/10.1038/s41586-021-03819-2- Lanzagorta-Ortega D., Carrillo-Pérez D. L., Carrillo-Esper R. (2023). Inteligencia artificial en medicina: presente y futuro. Gaceta Médica de México. https://doi.org/10.24875/gmm.m22000688 ****- Li, J., Wang, S., Zhang, M., Li, W., Lai, Y., Kang, X., Ma, W., & Liu, Y. (2024). Agent hospital: A simulacrum of hospital with evolvable medical agents. arXiv. https://doi.org/10.48550/arXiv.2405.02957- Ng, A. Y., Oberije, C. J. G., Ambrózay, É., et al. (2023). Prospective implementation of AI-assisted screen reading to improve early detection of breast cancer. Nature Medicine, 29, 3044–3049. https://doi.org/10.1038/s41591-023-02625-9- Olawade, D. B., Teke, J., Fapohunda, O., Weerasinghe, K., Usman, S. O., Ige, A. O., & David-Olawade, A. C. (2024). Leveraging artificial intelligence in vaccine development: A narrative review. Journal of Microbiological Methods 224 https://doi.org/10.1016/j.mimet.2024.106998- Opel, N., & Breakspear, M. (2026). Transforming mental health research and care through artificial intelligence. Science, 391(6782), 249–? https://doi.org/10.1126/science.adz9193- Rajpurkar, P., Irvin, J., Zhu, K., Yang, B., Mehta, H., Duan, T., Ding, D., Bagul, A., Langlotz, C., Shpanskaya, K., Lungren, M. P., & Ng, A. Y. (2017). CheXNet: Radiologist-level pneumonia detection on chest X-rays with deep learning (versión 3). arXiv. https://doi.org/10.48550/arXiv.1711.05225- Rejeleene R. & Mehta N. B. (2026). Artificial intelligence in medicine: How it works, how it fails. Cleveland Clinic Journal of Medicine. https://doi.org/10.3949/ccjm.93a.25089- Teo, Z. L., Thirunavukarasu, A. J., Elangovan, K., Cheng, H., Moova, P., Soetikno, B., Nielsen, C., Pollreisz, A., Ting, D. S. J., Morris, R. J. T., Shah, N. H. y Langlotz, C. P. (2025). Generative artificial intelligence in medicine. Nature Medicine, 31, 3270–3282. https://doi.org/10.1038/s41591-025-03983-2- Topol E. J. (2023). As artificial intelligence goes multimodal, medical applications multiply. Science. [https://doi.org/](https://doi.org/10.48550/arXiv.1711.05225)[10.1126/science.adk6139](https://doi.org/10.1126/science.adk6139)- Yip, M., Salcudean, S., Goldberg, K., Althoefer, K., Menciassi, A., Opfermann, J. D., Krieger, A., Swaminathan, K., Walsh, C. J., Huang, H., & Lee, I.-C. (2023). Artificial intelligence meets medical robotics. Science, 381(6654), 141–146. https://doi.org/10.1126/science.adj3312

In this powerful episode of Public Health Epidemiology Conversations, Dr. Huntley speaks with Chicago's first Black woman health commissioner, Dr. Olusimbo "Simbo" Ige, about tackling one of the nation's most alarming health disparities. When Black residents in Chicago were dying 15 years earlier than their neighbors, Dr. Ige stepped into leadership determined to change the trajectory. Drawing on decades of experience across Nigeria, Sub-Saharan Africa, and New York City, she shares how global public health lessons are shaping bold, community-centered strategies in Chicago today. From a 38% reduction in opioid deaths to early signs that the city's life expectancy gap is finally narrowing, Dr. Ige offers a candid look at what it takes to drive meaningful change in complex systems. She also speaks openly about the deeper barrier to progress. Not a lack of data, but a divide in values around who deserves public investment. Along the way, she and Dr. Huntley explore the importance of plain language, trusted community messengers, and storytelling as essential tools for effective public health leadership. This conversation is both inspiring and grounding for anyone committed to improving health equity.   Resources ▶️ Join the PHEC Podcast Community ▶️ Visit the PHEC Podcast Show Notes ▶️ DrCHHuntley, Public Health & Epidemiology Consulting

TWiM explains how to use microbes to enhance maize yield and reduce corn rootworm damage, and how the human microbiota modulates IgE-mediated reactions to foods through allergen metabolism. Hosts: Michael Schmidt, Petra Levin, and Michele Swanson. Guest: Mark O. Martin Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode Harnessing Microbes for Crop Production (Phytobiome J) Microbes take on corn rootworm (Science) Microbial metabolism of food allergens (Cell Host Microbe) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

With 29 million golfers in the U.S. and an estimated 7.25 million affected by spring allergies, seasonal respiratory symptoms can meaningfully affect performance and daily function. This episode explores how tree and grass pollen exposure, overlapping sensitizations, and indoor allergens can combine to drive rhinitis, fatigue, sleep disruption, and reduced daytime performance. We discuss regional pollen patterns, why pine pollen is often less clinically important than oak and juniper, how to avoid assuming a single trigger is the cause, and how localized respiratory allergen profiles with specific IgE testing can help clarify sensitization. Practical counseling includes using specific IgE results to help inform exposure reduction and environmental control to help improve symptom control and guide management. References and resources: https://www.thermofisher.com/phadia/us/en/resources/immunocast/masters-golf-respiratory-allergies-pollen-management.html

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world.Today, we delve into recent significant advancements and strategic maneuvers reshaping the landscape in these dynamic industries. AstraZeneca has made a notable stride with its chronic obstructive pulmonary disease (COPD) drug candidate, achieving remarkable efficacy in Phase 3 trials. This success is particularly significant given the historical challenges in this therapeutic area, where competitors like Roche and Sanofi have struggled to deliver consistent results. AstraZeneca's achievement not only highlights its innovative clinical development strategies but also offers renewed hope for COPD patients who have long awaited more effective treatment options.In a parallel move, AstraZeneca is pioneering in vivo CAR-T cell therapies, showcasing their potential despite safety concerns following a patient death during trials in China. The therapy's ability to eradicate cancer in three out of five patients underscores its promise as a revolutionary treatment for cancer, illustrating the need for ongoing safety evaluations as this technology develops.Meanwhile, Novartis continues to strategically expand its allergy treatment portfolio with a significant $2 billion acquisition of Excellergy. This deal centers around an anti-IgE program poised to potentially replace Xolair, Novartis's leading allergy medication. Such strategic moves underscore Novartis's commitment to remaining at the forefront of allergy therapeutics by harnessing biotechnological innovations to develop next-generation treatments. This acquisition complements existing assets like Xolair, an IgE blocker now approved for treating food allergies across different age groups, aiming to bolster Novartis's competitive edge in allergy therapeutics by providing a broader array of solutions.Otsuka Pharmaceutical is also making waves with its $1.2 billion acquisition of Transcend Therapeutics. This acquisition focuses on an MDMA analog for psychiatric conditions, marking Otsuka's deepening interest in mental health therapeutics and the burgeoning field of psychedelic compounds as viable psychiatric treatments. This move reflects a broader industry trend towards exploring unconventional therapeutic avenues to address complex mental health issues.On the regulatory front, Takeda is undergoing significant restructuring efforts aimed at achieving $1.3 billion in annual savings through reorganization. This reflects a broader industry trend towards optimizing operations to enhance efficiency and maintain competitiveness in an ever-evolving market landscape.In another noteworthy development, Rocket Pharmaceuticals has secured accelerated FDA approval for Kresladi, a gene therapy targeting severe leukocyte adhesion deficiency-1. This approval highlights the growing potential of gene therapies to meet unmet medical needs for rare diseases and sets an important precedent for other companies seeking expedited regulatory pathways for their gene therapy pipelines.In Alzheimer's research, both Eisai and Alzheon have made significant contributions, especially regarding high-risk patient subsets. Eisai presented real-world data on Leqembi at the AD/PD annual meeting, demonstrating safety and efficacy in patients with specific genetic profiles like APOE4 homozygotes. Concurrently, Alzheon provided insights into its candidate's performance in similar cohorts. These findings underscore personalized medicine's growing importance in neurodegenerative disease treatment.Oncology remains a critical area with Merck's announcement of its planned acquisition of Terns Pharmaceuticals for $6.7 billion. Driven by Terns' promising leukemia drug developments, this acquisition exemplifies how major players are diversifying their oncology pipelines to maintain market leadership amid approaching patent expiraSupport the show

Wheat allergy, celiac disease, and non-specific gluten intolerance all share overlapping gastrointestinal symptoms that can confound primary care diagnosis. This episode addresses the core diagnostic challenge of distinguishing IgE-mediated wheat allergy (including ω-5 gliadin–associated wheat-dependent exercise-induced anaphylaxis) from celiac disease and non-celiac gluten intolerance. We cover epidemiology, clinical presentations and timing of IgE reactions, component-resolved diagnostics, serologic algorithms for celiac disease, when to refer for biopsy, and management implications including gluten-free diet counseling and emergency planning for anaphylaxis. Practical takeaways emphasize improving diagnostic yield in primary care, appropriate use of specific IgE testing, and when specialist referral is necessary. References and resources: https://www.thermofisher.com/phadia/us/en/resources/immunocast/wheat-allergy-celiac-differential-diagnosis.html?cid=0ct_3pc_05032024_9SGOV4

In this episode of NP Pulse: The Voice of the Nurse Practitioner®️, Drs. Erin Sinnaeve and Julianne Doucette discuss immunoglobulin E (IgE)-mediated food allergies, current prevention strategies, diagnostic best-practices and evolving treatment options — including early allergen introduction, oral immunotherapy and biologic therapies — to support safe, evidence-based care.   Upon successful completion of this podcast, you will be able to:  Review the pathophysiology and subsequent patient journey associated with IgE-mediated food allergies.    Evaluate the trial data and practice-changing potential of monoclonal antibodies in a new era of food allergy management.    Develop evidence-driven care plans focused on mitigating patient and caregiver burden, and safely and effectively reducing IgE-mediated reactions in patients with food allergies.    A participation code will be provided at the END of the podcast — make sure to write this code down. Once you have listened to the podcast and have the participation code, return to this activity in the AANP CE Center and follow these steps:  Register for this activity.  Click on the "Next Steps" button.  Enter the participation code that was provided.  Complete the activity evaluation.  This will award your continuing education (CE) credit and certificate of completion.  1.25 CE will be available through March 31, 2027.  Listeners are encouraged to explore the accompanying food allergy point-of-care tool to support clinical decision-making.   The Hidden Burden: Understanding Food Allergies and Their Impact This podcast is supported by an education grant from Genentech, a member of the Roche Group. 

Is it really a food allergy or something else entirely?Are stomach aches, bloating, and food fears always caused by specific foods?And how do parents know when eliminating foods is helping… or quietly making things worse?In this episode, we're tackling one of the most confusing topics in youth athletics: food allergies vs. food intolerances  and how both intersect with under-fueling in gymnastics. I'm joined by a repeat guest and allergy-immunology nurse practitioner (and fellow gymnast mom) to break down what's real, what's misunderstood, and what every parent and coach needs to know.Because while true food allergies absolutely exist and require strict management, many gymnasts are unnecessarily restricting foods due to fear, misinformation, or non-specific symptoms that are actually caused by chronic under-fueling. And in a sport where athletes are already at high risk for not eating enough, removing foods without clear evidence can quietly worsen growth, digestion, recovery, and performance. In this episode, we cover: ❗What true food allergies actually look like (and how they're diagnosed) ❗The difference between IgE allergies, intolerances, and gut symptoms ❗Why food elimination is often the knee-jerk reaction to GI issues ❗How under-fueling disrupts digestion and mimics food intolerance ❗The truth about airborne allergies and cross-contamination fears ❗Why IgG “food sensitivity tests” are misleading and often harmful ❗Lactose intolerance, gluten concerns, and when they're real ❗How unnecessary food restriction can worsen growth, hormones, and performance ❗What parents and coaches should watch for in gymnasts with chronic symptomsWe also share real clinical scenarios from gymnasts misdiagnosed with food intolerances to athletes who improved dramatically once fueling was addressed first. If your gymnast has stomach aches, fatigue, frequent illness, food fears, or multiple food restrictions, this conversation is essential.Because here's the truth:Not every stomach ache is a food allergy.Not every reaction needs elimination.And sometimes the real issue isn't what a gymnast is eating but how much. This episode will help you feel more confident navigating food fears, medical advice, and nutrition decisions so your gymnast can stay healthy, strong, and thriving.Links & ResourcesThe Balanced Gymnast® Program (Level 5–10)Connect with Christina on Instagram @the.gymnast.nutritionist christinaandersonrdn.com

Having finally perfected the art of fight picking, Phil is now the main host of Heavy Hands.  Don't miss the first Heavy Henka of the year! Join us as we break down the conclusion of this month's outrageous grand sumo tournament: https://www.patreon.com/heavyhands  Predatory instinct: how Max Holloway attacks: https://open.substack.com/pub/facepunching/p/predatory-instinct-how-max-holloway?r=evbq&utm_campaign=post&utm_medium=web&showWelcomeOnShare=false  Heavy Hands merch: https://www.redbubble.com/shop/ap/64577943?asc=u  CONTENTS: 00:00 Intro 00:30 Strickland vs Hernandez 27:31 Neal vs Medic 36:50 Ige vs Costa 52:45 Moreno vs Kavanagh 1:17:40 Vera vs Martinez  

What makes Lyme disease resolve quickly in some people but turn into a life-altering chronic illness in others? In this episode, world-leading immunologist Dr. Michal “Mikki” Tal, Principal Scientist at MIT, explains what her team is discovering through the MAESTRO Study — the largest clinical research project in MIT's history and the first of its kind to include real Lyme patients in a multi-system biological analysis. Dr. Tal's work sits at the intersection of immunology, bioengineering, and women's health, uncovering how infections like Lyme and COVID can cause persistent inflammation, immune miscommunication, and hormonal imbalance. Through MAESTRO, she's mapping how recovery breaks down — and what can be done to predict, prevent, and ultimately reverse chronic illness.

Episode 43 - Wendy Elverson - Managing Food Protein–Induced Allergic Proctocolitis (FPIAP)In this episode of Nutrition Pearls: the Podcast, co-hosts Megan Murphy and Bailey Koch speak with Wendy Elverson, RD, CSP, LDN about the latest research and best practice for managing infants with Food Protein-Induced Allergic Proctocolitis (FPIAP). Wendy is a registered dietitian who has specialized in clinical pediatric nutrition for more than 25 years. Currently, she is a Senior Clinical Nutrition Specialist at Boston Children's, with expertise in pediatric food allergies and feeding disorders. Wendy is a provider in several multidisciplinary, allergy-focused clinics, including the Atopic Dermatitis Center, the FPIES Clinic, and the EGID Clinic. Wendy has been an active member of CPNP since 2015 and has had many roles, currently serving on the NASPGHAN Public Education Committee. Wendy was the previous Chair of INDANA (International Network for Diet and Nutrition in Allergy) and is the current chair of the Nutrition Work Group of the Allied Health Assembly of the American Academy of Allergy, Asthma, and Immunology (AAAAI). She is a proud co-author of several publications, including a free resource for caregivers of children with milk and egg allergies, tolerant to baked milk and egg, Muffins and More: A Baked Milk and Baked Egg Recipe and Guidebook. Wendy was also the recipient of the 2025 CPNP Dietitian of Excellence Award. References: Mahoney, L. B., et al. (2025). Food protein-induced allergic proctocolitis: What do we know and where are we going? Current Treatment Options in Pediatrics, 11(1). https://doi.org/10.1007/s40746-025-00346-4Meyer, R., et al. (2025). An update on the diagnosis and management of non-IgE-mediated food allergies in children. Pediatric Allergy and Immunology, 36(3). https://doi.org/10.1111/pai.70060 Franco, C., Fente, C., Sánchez, C., Lamas, A., Cepeda, A., Leis, R., & Regal, P. (2022). Cow's Milk Antigens Content in Human Milk: A Scoping Review. In Foods (Vol. 11, Issue 12). https://doi.org/10.3390/foods11121783Gamirova, A., et al. (2022). Food proteins in human breast milk and probability of IgE-mediated allergic reaction during breastfeeding: A systematic review. Journal of Allergy and Clinical Immunology: In Practice, 10(5). https://doi.org/10.1016/j.jaip.2022.01.028Meyer, R., et al. (2023). WAO DRACMA guideline update VII: Milk elimination and reintroduction in cow's milk allergy diagnosis. World Allergy Organization Journal, 16(7). https://doi.org/10.1016/j.waojou.2023.100785Produced by: Corey IrwinNASPGHAN - Council for Pediatric Nutrition Professionalscpnp@naspghan.org

We've all seen it: the patient whose chart is “flagged” with a penicillin allergy, but when you dig into the history, the story doesn’t quite add up. Maybe it was a stomach ache in the 90s, or maybe they're just carrying a “inherited” allergy from a parent. In this episode of EM Pulse, we sit down with ED Clinical Pharmacist Haley Burhans to discuss why these labels are more than just a nuisance—they're a clinical liability—and how a simple tool can empower you to fix them on the fly. The Hidden Danger of the “Safe” Choice Choosing a non-beta-lactam antibiotic because of a questionable allergy label feels like the path of least resistance, but the data tells a different story. We explore how “playing it safe” can actually lead to: Worse Outcomes: Why second line antibiotics often mean higher treatment failure rates. The “Superbug” Factor: The surprising link between penicillin allergy labels and the rise of MRSA and VRE in our communities. The C. diff Connection: Why alternative choices might be setting your patient up for a much more difficult recovery. The Solution: The PEN-FAST Score How do you move from “I think this might not be a true allergy” to “I am confident this antibiotic is safe”? Haley introduces the PEN-FAST score, a validated scoring tool designed to risk-stratify patients based on a few key historical questions. The Mnemonic: We break down the PEN-FAST acronym so you know exactly which three questions to ask to risk-stratify your patient in seconds. IgE vs. The Rest: Learn to distinguish between the “true” dangerous hypersensitivity and the delayed reactions that shouldn’t stop you from using the best drug for the job. The “Amoxicillin Rash”: We dive into this common pediatric “gotcha.”, why many kids end up with a lifelong allergy label after a routine ear infection, and why it often has nothing to do with the drug itself. The Bottom Line: Patients with low PEN-FAST scores are considered low risk, making an oral challenge under observation in the ED a reasonable option. Higher scores may require shared decision-making or referral. Why the ED is the Perfect Place for a “Challenge” Delabeling isn’t just for the allergist’s office. We argue that the Emergency Department is actually the ideal setting to challenge these allergies. The “Oral Challenge”: Learn the practical steps for performing a trial dose in the department. Safety First: Why your environment and expertise make you uniquely qualified to handle the “what-ifs” better than anyone else. Key Takeaways Question the Label: The vast majority of reported penicillin allergies are inaccurate due to patients outgrowing the allergy or misinterpreting common side effects as allergic reactions. History is Everything: Dig deeper than just “rash.” Ask about the timing relative to the dose, specific appearance (hives vs. flat rash), and what treatment was required (epinephrine vs. antihistamines). Use PEN-FAST: Utilize this tool to objectify the risk. Document Tolerance: Even if you don’t fully delete the allergy label, if you successfully treat the patient with another beta-lactam (like ceftriaxone), document that tolerance clearly to aid future clinicians. Cephalosporins are likely safe: Later-generation cephalosporins generally have very low cross-reactivity and are usually safe options even in truly allergic patients How do you handle documented penicillin allergies? Do you use the PEN-FAST tool? Share your experience with us on social media @empulsepodcast or at ucdavisem.com Hosts: Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis Guests: Haley Burhans, PharmD, Emergency Medicine Clinical Pharmacist at UC Davis Resources: PEN-FAST Score on MDCalc Penicillin Allergy Evaluation Should Be Performed Proactively in Patients with a Penicillin Allergy Label – A Position Statement of the American Academy of Allergy, Asthma & Immunology Staicu ML, Vyles D, Shenoy ES, Stone CA, Banks T, Alvarez KS, Blumenthal KG. Penicillin Allergy Delabeling: A Multidisciplinary Opportunity. J Allergy Clin Immunol Pract. 2020 Oct;8(9):2858-2868.e16. doi: 10.1016/j.jaip.2020.04.059. PMID: 33039010; PMCID: PMC8019188. Yang C, Graham JK, Vyles D, Leonard J, Agbim C, Mistry RD. Parental perspective on penicillin allergy delabeling in a pediatric emergency department. Ann Allergy Asthma Immunol. 2023 Jul;131(1):82-88. doi: 10.1016/j.anai.2023.03.023. Epub 2023 Mar 27. PMID: 36990206. *** Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.  

Contributor: Aaron Lessen, MD Educational Pearls: What is anaphylaxis and what are its treatments?  Anaphylaxis is a broad term for potentially life threatening allergic reactions that can progress to cardiovascular collapse (anaphylactic shock).  It is triggered by IgE and antigen cross-linking on mast cells to induce degranulation and the release of histamines, which can cause diffuse vasodilation and respiratory involvement with end-organ hypoperfusion. First line treatment is the immediate administration of epinephrine at 0.01 mg/kg (max dose for pediatrics is 0.3 mg and for adults is 0.5 mg) as well as removal of the offending agent causing the reaction. Additional pharmacologic treatments such as anti-histamines and steroids should be considered but not used instead of epinephrine when anaphylactic shock is evident as the sole therapy. What is biphasic anaphylaxis and what is its occurrence? Biphasic anaphylaxis is the return of anaphylactic symptoms after the initial anaphylactic event. Previous studies have reported an incidence ranging from 1-20% of patients having an initial anaphylactic reaction having biphasic anaphylaxis, at a range of time from 1-72 hours. The mechanism of biphasic anaphylaxis is not completely known, but can be contributed to by initial interventions wearing off (and why patients will be monitored for 2-4 hours after initial symptoms and treatment), or delayed immune mediators beginning to take effect. Recent studies show that the rate of biphasic anaphylaxis may be closer to 16% occurrence with a median time of occurrence being around 10 hours. What is the key take away and patient education on biphasic anaphylaxis? After patients have been observed for the initial 2-4 hours in the emergency room, they are generally safe to go home. Patients should be informed of the need to carry an Epi-Pen for similar anaphylactic reactions, and informed that there is a chance within the next day (10-20 hours) that they may have the symptoms occur once again. The biphasic reaction may be more mild, and patients should be educated on how to treat it and to seek immediate emergency care if the symptoms do not improve. References Golden DBK, Wang J, Waserman S, et al. Anaphylaxis: A 2023 practice parameter update. Annals of Allergy, Asthma & Immunology. 2024;132(2):124-176. doi:10.1016/j.anai.2023.09.015 Rubin S, Drowos J, Hennekens CH. Anaphylaxis: Guidelines From the Joint Task Force on Allergy-Immunology Practice Parameters. afp. 2024;110(5):544-546. Weller KN, Hsieh FH. Anaphylaxis: Highlights from the practice parameter update. CCJM. 2022;89(2):106-111. doi:10.3949/ccjm.89a.21076 Gupta RS, Sehgal S, Brown DA, et al. Characterizing Biphasic Food-Related Allergic Reactions Through a US Food Allergy Patient Registry. The Journal of Allergy and Clinical Immunology: In Practice. 2021;9(10):3717-3727. doi:10.1016/j.jaip.2021.05.009 Summarized by Dan Orbidan OMS2 | Edited by Dan Orbidan & Jorge Chalit OMS4 Donate: https://emergencymedicalminute.org/donate/ Join our mailing list: http://eepurl.com/c9ouHf

MMA Lock of the Night is back to give you breakdowns and predictions for UFC Houston: Strickland vs Hernandez. Also on the card, Neal vs Medic, Ige vs Costa, Spivac vs Delija, and Smith vs Harrell.

Nearly 11% of U.S. adults meet criteria for a convincing food allergy, yet most clinicians underestimate both the prevalence and unique challenges of adult-onset disease. This episode addresses the frequent misdiagnosis and clinical uncertainty surrounding new symptoms in adults by highlighting epidemiology, risk factors for delayed and severe reactions, high-yield history-taking, diagnostic pitfalls, and guideline-supported use of specific IgE and component-resolved diagnostics. Listeners will learn to distinguish allergy from intolerance, understand psychosocial burdens, apply evidence-based testing algorithms, and recognize when to refer for oral food challenge or advanced management. With practical insights into differential diagnosis, best practices for test interpretation, and strategies to streamline care in busy settings, this episode equips providers to close the adult allergy diagnosis gap and optimize patient safety. Resources and references: https://www.thermofisher.com/phadia/us/en/resources/immunocast/adult-onset-food-allergy-diagnosis-management.html?cid=0ct_3pc_05032024_9SGOV4

"It's not really true that if you just fix your gut, you're fixing everything." If you have eczema, psoriasis, rosacea, or hives and nothing seems to work... if you've tried every elimination diet and "heal your gut" protocol only to see your skin get WORSE... if you've bounced from functional doctor to functional doctor without answers... this episode changes everything.Dr. Terri sits down with Jennifer Fugo, a clinical nutritionist who specializes exclusively in chronic skin conditions (and host of the Healthy Skin Show podcast with nearly 400 episodes), for one of the most eye-opening and controversial conversations about skin health you'll ever hear. This isn't your typical "just heal your gut" advice - it's the truth about why that approach FAILS for most people with skin issues and what actually works. WHAT YOU'LL DISCOVER: → Why "heal your gut" advice is incomplete and does a MASSIVE disservice to skin patients → The shocking truth: elimination diets can cause IgE anaphylactic food allergies in adults → Why you're bouncing from practitioner to practitioner and getting worse, not better → The Phase 2 liver detox pathway that 99% of practitioners overlook→ How milk thistle and dandelion root could be making your skin WORSE (ragweed allergens) → The cross-reactive allergen problem that practitioners don't check for → Why food is just a Band-Aid (not the root cause) for most skin conditions This isn't about ONE thing fixing everything. It's about finding YOUR root cause combo. ---TIMESTAMPS: 0:00 - Intro 1:30 - Jennifer's eczema story (and why it sparked her mission) 4:20 - Why skin issues are different than "hidden" conditions 6:15 - The "heal your gut" myth that's failing patients 7:45 - Why people bounce between practitioners getting worse 10:30 - It's not ONE thing - it's multiple root causes 12:15 - The Phase 2 liver detox pathway everyone overlooks 14:40 - Why milk thistle might be making you worse 17:20 - The glycine secret for liver support 20:15 - Cross-reactive allergens practitioners don't check 25:30 - Rosacea and stomach acid connection 30:55 - Demodex mites and rosacea (what to ask your doctor) 33:10 - How to advocate for yourself in limited appointment times 37:00 - The elimination diet danger (developing anaphylactic allergies) 41:30 - Food is a Band-Aid, not the cure ---RESOURCES MENTIONED:• The Healthy Skin Show Podcast https://www.skinterrupt.com/listen/ • Jennifer Fugo's Practice https://www.skinterrupt.com/book-a-session/ • Evexias Health Solutions (Episode Sponsor) Website: https://www.evexias.com Find a provider near you ---SUBSCRIBE for more episodes challenging conventional health wisdom and exploring what ACTUALLY works.If this episode gave you answers you've been searching for, LIKE and SHARE it with someone struggling with chronic skin conditions.COMMENT below: Have you been told to "just heal your gut" for your skin? What happened? ---ABOUT THE DR. TERRI SHOW:Dr. Terri brings you honest conversations about health, wellness, personal transformation, and the topics that matter most in today's world. From integrative medicine to nutrition to policy reform, we explore it all with expert guests who are making a real difference.New episodes weekly. Subscribe and turn on notifications so you never miss an episode. ---The Dr. Terri Show is presented by Evexias Health Solutions. For more, visit: https://www.evexias.com Connect more with Dr. Terri:

For primary care providers, seeing a patient presenting with atopic dermatitis (eczema) is common, yet misconceptions persist regarding its underlying cause and optimal management. This episode tackles the critical clinical dilemma: when and how should specific IgE testing for food and environmental allergens shape routine eczema care? Key topics include the evolution of pathophysiology—shifting focus from allergy-driven disease to barrier dysfunction and type 2 inflammation—plus risk stratification, differential diagnosis, the role and interpretation of specific IgE tests, evidence-based guideline updates, environmental and food allergen impacts, targeted therapeutics, and practical patient counseling. Special attention is given to environmental triggers such as dust mites and pet dander and structured elimination diets. Clinicians will gain actionable insights on refining diagnostic workups, individualizing treatment plans, and supporting long-term disease control in pediatric and adult eczema populations. References and resources: https://www.thermofisher.com/phadia/us/en/resources/immunocast/eczema-essentials-atopic-dermatitis-diagnosis-management.html?cid=0ct_3pc_05032024_9SGOV4

Why Managing Symptoms Isn't Enough for Kids With Eczema and AllergiesThis week on the podcast, we're continuing our eczema and allergies series with topic two and it's a juicy one! This time, we're talking about something so many parents feel in their bones but don't always have the words for: when it comes to eczema and allergies, why does it feel like we're constantly managing symptoms… but rarely getting real answers?

Broadcast from KSQD, Santa Cruz on 1-15-2026: An emailer from Switzerland asks about fluorescein angiography requested before her first retina appointment. Dr. Dawn suspects protocol-based medicine screening for macular degeneration and suggests negotiating to see the doctor first given her different reason for seeing a retinal specialist. She encourages patients to maintain agency in medical settings. An emailer asks about creatine supplements. Dr. Dawn notes it helps muscle development in people doing weight training at 3-5 grams daily, but does nothing for aerobic-only exercisers. Claims about cognition and mood lack solid research. She advises against high-dose "loading," and cautions that creatine causes fluid retention problematic for congestive heart failure and should be avoided with stage 3 or higher kidney disease. Dr. Dawn reminds listeners it's not too late for flu shots, noting this season's H3N2 strain emerged after vaccine formulation was finalized. She laments mRNA vaccine research defunding, as that technology allows rapid reformulation. She describes organoids—tissues grown from stem cells that self-organize into primitive organ structures, enabling rapid drug screening without animal testing. Stanford researchers created assembloids by placing four neurological organoids together that spontaneously connected and built the ascending sensory pain pathway, offering new approaches to studying chronic pain. Dr. Dawn explains research showing satellite glial cells transfer healthy mitochondria to spinal sensory neurons through tunneling nanotubules. When this transfer fails, neurons fire erratically causing pain. Infusing healthy mitochondria into mouse spinal columns cured peripheral neuropathy—suggesting future periodic infusion treatments for humans. She reports Texas A&M researchers created "nanoflowers" from molybdenum disulfate that double stem cell's mitochondrial production, potentially supercharging regenerative medicine for conditions including Alzheimer's and muscular dystrophy. A caller asks about flu vaccines with egg allergy. Dr. Dawn explains that his gastrointestinal reactions to eggs differ from dangerous IgE allergies causing hives or anaphylaxis—GI intolerance doesn't preclude vaccination. Dr. Dawn reveals that 20 years of Parkinson's research followed a false lead. MRI showed increased iron in patients' brains, prompting iron chelation trials—which worsened symptoms. The problem: MRI detects paramagnetic ferric iron (stored, inert) not ferrous iron (biologically active). Patients accumulate useless ferric iron but are deficient in usable ferrous iron. Earlier 1980s studies showing that iron supplementation helped were ignored and abandoned prematurely. She suggests Parkinson's patients discuss iron supplementation with neurologists. She will post the link in the resources page on her website. A caller concerned about early Parkinson's describes tremors and balance problems in darkness. Dr. Dawn suggests darkness-related symptoms sound more like peripheral neuropathy than Parkinson's, recommending neurological examination and screening for diabetes, B vitamin deficiency, or heavy metal exposure. She confirms that sedentary lifestyle reduces mitochondrial production while progressive exercise builds both muscle and mitochondria.

As parents, we expect the occasional food reaction. Maybe a rash, some fussiness, or a tummy ache. But what happens when your child suddenly becomes violently ill hours after eating something they've had before, and no one seems to know why? That was my reality when Jasper had this kind of reaction to shrimp. Inside this episode, I'm digging into: What FPIES is and how it differs from IgE-mediated food allergies Common trigger foods and why reactions can show up hours later Our experience with Jasper's shrimp reaction (and what we learned from it) How to navigate fear around food after a reaction Why trusting your instincts and advocating for your child matters --- Show Notes: Sign up for a 1:1 Discovery Call Join the Imperfectly Paige Wellness Community Join the Compass Method DIY Program Jump inside my Rock the Bloat Minicourse Get my Core-Gi Workout Program with the exclusive listener discount! Join my Brain Rewiring Masterclass You can learn more about me by following on IG @imperfectlypaigewellness or by checking out my blog, freebies, and offers on my website: https://imperfectlypaigewellness.com Please share with #PaigeTalksWellness to help get the word out about the show - and join the Imperfect Health Fam over on Facebook.

What do you think of serrapeptase for reducing coronary plaque?We were told to get a TDAP vaccine or we wouldn't be able to see our new grandchild for 8 weeks!Do I have lupus?Which supplements tend to reduce negative effects of X-rays?

The Holiday Season in NYCPeanut allergies cause and effectWhich calcium supplements can I take if I'm allergic to cow protein?Can my husband take saw palmetto in lieu of his prostate medications?What do you think of traction to help bulging discs?What is your take on green powder supplements?

Guest: Dr. Jayne Danska is a Senior Scientist, Genetics and Genome Biology at the Hospital for Sick Children Research Institute. She is also Associate Chief of Research, Faculty Development and Diversity, and Professor at the University of Toronto. Her research focuses on the microbiome in type 1 diabetes. She discusses insights from longitudinal human studies and mouse models. (40:00) Featured Products and Resources: Register now for IMMUNOLOGY2026! Wallchart: T Cell Nomenclature: From Subsets to Modules The Immunology Round Up Vaccination for Anaphylaxis –  A vaccine against IgE protected against anaphylaxis in a mouse model. (2:53) How RSV Can Lead to Asthma – Researchers identified maternal allergy and neonatal RSV infection as converging Fc receptor-dependent risk factors for asthma. (9:50) Antigen Presentation for MAIT Cell Immunity – Macrophages are key for MR1 antigen presentation and MAIT cell immunity. (20:30) HIV Remission after Stem Cell Transplantation – After an allogeneic stem cell transplant, a patient discontinued antiretroviral therapy and sustained HIV remission for over six years. (27:00) Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Broadcast from KSQD, Santa Cruz on 12-04-2025: Dr. Dawn opens with an experimental vaccine that prevents severe allergic reactions by targeting IgE antibodies. The vaccine could eventually replace current monoclonal antibody treatments like omalizumab that require injections every two weeks. She explains how adjuvants work in vaccines as additives that irritate the immune system enough to notice the vaccine target. Aluminum hydroxide is s common adjuvant. Modern vaccines use small pathogen fragments rather than whole organisms, requiring adjuvants to trigger adequate immune response. Dr. Dawn expresses concern about the US Advisory Committee on Immunization Practices reviewing aluminum adjuvants this week. A Danish study of over one million children finding no connection between aluminum with autism and ADHA contradicts RFK,Jr's public claims.She worries that removing aluminum could devastate vaccine effectiveness and children's health, noting that whenever vaccination rates drop, diseases like measles return to native circulation. She recounts pertussis vaccine history—when Japan stopped vaccination due to rare adverse reactions (approximately one death per million doses), they lost about 5,000 children to whooping cough in the first year. The newer acellular vaccine using pathogen fragments plus adjuvants is safer but only lasts 4-5 years versus lifetime immunity from the older whole-cell version, necessitating "cocooning" strategies where everyone contacting newborns must be recently vaccinated. Dr. Dawn describes a vaccine to prevent fentanyl from reaching the brain now starting clinical trials in the Netherlands. It pairs a fentanyl-like molecule with a carrier protein large enough to trigger antibody production. Once primed, the immune system attacks any fentanyl entering the blood, preventing highs and overdoses—potentially helping people in addiction recovery and those accidentally exposed through contaminated drugs. She reports the first documented death from alpha-gal syndrome. Alpha-gal is a meat allergy triggered by Lone Star tick bites; the tick essentially vaccinates humans against the alpha-galactosidase protein found on beef and pork. Cases have increased since 2010 as climate change expands the tick's range northward, yet a 2023 survey found 42% of doctors had never heard of the condition. Dr. Dawn highlights research from Edith Cowan University showing that blood drawn after exercise suppresses cancer cell growth when added to tumor cultures. In breast cancer survivors, plasma from high-intensity interval training or weight lifting caused cancer cells to stop growing or die; blood drawn before exercise had no effect. The key mechanism involves myokines, particularly IL-6, released by contracting muscles. A Stanford study found colon cancer survivors who exercised were 37% less likely to experience recurrence. A caller asks about pig-to-human heart transplants and mask recommendations. Dr. Dawn clarifies that newer xenotransplant pigs have more genes edited to reduce rejection compared to the 2022 case. For masking, she recommends context-dependent use—especially in public restrooms where toilet flushing aerosolizes COVID-containing particles, transportation hubs, and hospitals, noting that COVID vaccination prevents death but not infection or long COVID. She advises the same caller about spacing vaccines because adjuvant loads stack. Most vaccines can be combined safely, but she recommends against pairing COVID and Shingrix vaccines due to their heavy adjuvant content—wait at least ten days between them. She suggests inducing a sweat the night of vaccination through hot baths, saunas, or exercise to reduce adjuvant-related discomfort without diminishing antibody response. Dr. Dawn discusses seasonal affective disorder. She recommends 5,000 units of vitamin D3 and morning light exposure. She suggests that sun avoidance advice may have gone too far. A UK study of 3.36 million people found 12-15% lower mortality with greater UV exposure even accounting for skin cancer risk. A Swedish study following 30,000 women for 20 years found sun-seekers had half the mortality risk. Benefits may involve nitric oxide production lowering blood pressure, with each 1,000 km from the equator correlating with 5 mmHg higher blood pressure. Lack of bright outdoor light also contributes to childhood myopia, with rates exceeding 80% in some Asian cities. Dr. Dawn concludes with Danish microbiologists at Copenhagen's Alchemist restaurant reviving an old Bulgarian practice of fermenting milk with live red wood ants. The resulting yogurt, cheese, and ice cream contain far more beneficial microbes than commercial products, with a complex lemony acidity. Only live ants work, and wild ants may carry parasites dangerous to humans.

In this conversation, we pull back the curtain on alpha-gal syndrome diagnostic testing at Thermo Fisher Scientific with Gary Falcetano, PA-C. Gary shares insights into how the alpha-gal syndrome test works and answers some of our most frequently asked questions. How do you talk to your provider about being tested? Is the test covered by insurance? What provider can order the test? He also dives into how Allergy Insider, Thermo Fisher's patient resource, is bringing alpha-gal into the conversation. Tune in now to learn more! Gary Falcetano, PA-C, serves as Senior Manager Global Medical and Scientific Affairs for allergy at Thermo Fisher Scientific. Gary has been a Board Certified Physician Assistant for over 28 years, and is the host of Allergy Insider's ImmunoCAST podcast.Visit Allergy Insider to learn more about their patient resources and be sure to follow on social media: @allergyinsider

Thanksgiving and overindulgenceA food poisoning incidentObservations on health at ThanksgivingWhat do you think of online sites offering prescriptions for hair loss via a questionnaire?

My granddaughter suffers from menstrual cramps.  Do you have any suggestions?Do you recommend nicotinamide daily to prevent recurrence of basal cell cancers?What works best to lower fibrinogen?I've been on Ozempic for a year and have diarrhea every morning!Is bypass surgery still being done?Would you recommend Bergamot for fatty liver?

On episode #94 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/11/25 – 11/19/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus (Science Translational Medicine) Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice (CID) Antimicrobial drug-resistant Neisseria gonorrhoeae (GC) infections in men using doxycycline postexposure prophylaxis. A substudy of the ANRS 174 DOXYVAC trial (CID) HIV Pre-exposure Prophylaxis Does Not Increase Gonorrhea and Chlamydia Incidence in Young Black and Hispanic Men who Have Sex With Men: An Observational Cohort Study (OFID) Bacterial Global and regional knowledge of antibiotic use and resistance among the general public: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) Infant Botulism Outbreak Linked to Infant Formula, November 2025 (CDC: Botulism) Outbreak Investigation of Infant Botulism: Infant Formula (November 2025) (FDA) Vitamin D deficiency at hospital admission with community-acquired pneumonia is associated with increased risk of mortality: A Prospective Cohort Study (OFID) Bat-Associated Hemotropic Mycoplasmas in Immunosuppressed Children, Spain, 2024 (Emerging Infectious Diseases) A Multicomponent Intervention to Improve Maternal Infection Outcomes (NEJM) Fungal The Last of US Season 2 (YouTube) Increasing Fluconazole Resistance in Candida parapsilosis: A 10-Year Analysis of Blood Culture Isolates at a US Reference Laboratory (2015–2024) (JID) British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update (LANCET: Infectious Diseases) In Vivo Evolution of Candida auris Multidrug Resistance in a Patient Receiving Antifungal Treatment (JID) Parasitic Implications of a fatal anaphylactic reaction occurring 4 hours after eating beef in a young man with IgE antibodies to galactose-α-1,3-galactose (JACI: Journal of Allergy and Clinical Immunology In practice) WHO recommends R21/Matrix-M vaccine for malaria prevention in updated advice on immunization (WHO) Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi (LANCET: Global Health) A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication? (PLoS Neglected Tropical Diseases) Miscellaneous IL12RB1 deficiency appearing in North America: expanding the clinical phenotypes (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

Persistent congestion, pressure, or a reduced sense of smell often gets mistaken for allergies or a stubborn cold when it may be something more, like chronic rhinosinusitis with nasal polyps (CRSwNP). Getting the right diagnosis is the first step toward real relief. Dr. Tonya Farmer, a board-certified ENT, joins Kortney and Dr. G to explain how chronic rhinosinusitis with nasal polyps (CRSwNP) is diagnosed. She walks us through the full evaluation: what symptoms matter, what a nasal endoscopy actually shows, when a CT scan is needed, and how type 2 inflammation fits into the picture. What we cover about diagnosing CRSwNP: Key symptoms: Persistent congestion, drainage, facial pressure, and especially loss of smell are major red flags for CRSwNP. Why duration matters: Chronic means 12 weeks or longer. If symptoms keep coming back or never truly improve, it's time to look deeper. The physical exam: ENTs use nasal endoscopy to see swelling, mucus, or polyps that aren't visible from the outside. When CT scans are needed: Imaging helps confirm sinus inflammation and shows the extent of polyp growth. Additional testing: Allergy testing, IgE levels, eosinophils, and other immune markers help identify type 2 inflammation and guide next steps. When to see a specialist: If antibiotics, steroids, or over-the-counter treatments aren't helping, ask for a referral to an allergist or ENT. Early diagnosis can prevent worsening symptoms and reduce the need for surgery. Set the foundations: Ep. 133: What is Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)? ___   Made in partnership with The Allergy & Asthma Network. Thanks to Sanofi for sponsoring today's episode.  This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Want to heal your child's eczema without steroids and save $200 this week? Click here to get started → EczemaKids.com Use code EPISODE200 to get $200 off the Eczema Elimination Method.... the COMPLETE eczema-reversal system that actually works. This offer is good for one week only and ends Tuesday, November 4th, 2025. If your child's ever had an allergy test hoping for answers, only to walk out more confused or flaring, this episode is for you. As we celebrate 200 episodes (and my birthday week!), I'm breaking down what allergy tests actually measure, why kids with eczema often react badly, and how to tell the difference between true, serious IgE allergies and immune overload. We'll talk about why scratch tests and immunotherapy often do more harm than good for eczema families, what to do if your child already flared after testing, and how to start healing their skin and gut from the inside out.