Podcasts about Metabolism

Episode Description: In today's episode (originally recorded as an Instagram Live), I'm answering some of your most pressing questions about insulin resistance and the buzz around GLP-1 medications—through the lens of real healing, root cause solutions, and God's design for the body. We're talking about: Why you might still have insulin resistance even if your labs look “normal” What actually happens when insulin is high—even if your blood sugar isn't How long it takes to reverse insulin resistance (and what most people get wrong) Why some people struggle with insulin resistance even when they're not overweight What GLP-1 is, and why it affects hunger and fat loss How to naturally support GLP-1 function without meds What happens when you stop taking medications like Ozempic or Mounjaro And the truth about whether GLP-1 meds fix root issues or just mask symptoms Plus: I'm sharing the exact free resources and tools I use with clients to naturally support insulin, blood sugar, and hormone balance—without gimmicks or restriction.

Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. In Part 2 of this powerful interview, legendary protein researcher Dr. Donald Layman returns to the Optimal Protein Podcast to unpack some of the most misunderstood concepts in nutrition today—and to reveal potential groundbreaking changes to the U.S. dietary guidelines around protein, red meat, saturated fat, and carbohydrates. Dr. Layman breaks down what the science actually says about protein dosing, timing, oxidation, and muscle uptake—and who truly needs to worry about protein distribution. Vanessa and Dr. Layman also discuss:

If you're frustrated by weight gain, depleted energy, or feel like your metabolism suddenly hit a wall, you're not alone—especially if you're navigating the hormonal rollercoaster of perimenopause or menopause. In this empowering episode, health journalist Natalie Tysdal is joined by Stephanie Crassweller, international speaker, master's-level nutrition coach, and host of the Metabolism and Menopause Podcast. Together, they dive into the not-so-obvious drivers behind women's metabolism in midlife—and what you can actually do about them. Expect practical strategies, compassionate insight, and the truth about why “eat less, move more” simply isn't the answer for women in this season of life. Learn how to work with your shifting hormones and stress response—not against them—to support sustainable energy, metabolism, and well-being. 3 Key Takeaways from This Episode Stress is the Unsung Metabolism Saboteur Chronic stress and elevated cortisol disrupt everything from sleep and gut health to thyroid function, making it harder to burn fat and easier to gain weight. Recognizing and managing stress is essential to healing your metabolism. Eating Less Isn't Always Better Undereating and inconsistent fueling push your body into fight-or-flight mode, increasing inflammation and triggering metabolic slowdown. For many women, doing less with more intention works better than pushing harder. Hormones Change the Metabolic Game As estrogen and progesterone decline, the body loses its built-in stress protection, exposing hidden issues with blood sugar, thyroid, and inflammation. Understanding your hormonal landscape helps you make changes that work for your unique body. In This Conversation, We Cover   Why traditional weight loss approaches often backfire after age 35   The hidden impact of under-eating and why breakfast matters   Simple first steps for women overwhelmed by nutrition “rules”   The difference between male and female metabolism   How routines, meal prep, and smart shortcuts support success   What Dutch testing is and when to consider hormone labs   Why sustainable food swaps and real-life habits matter more than perfection More About This Episode Stephanie Crassweller brings decades of experience in women's health, holding a master's degree and certifications in nutrition coaching, functional health, personal training, and exercise therapy. In this episode, she explains how stress, sleep, under-fueling, and hormone shifts affect metabolism, especially in perimenopause and menopause. She and Natalie discuss how even “healthy” processed foods and common dieting advice can work against women's health goals. Instead, they share how to simplify nutrition, embrace whole foods, support hormone balance, and develop easy habits that reduce stress and increase energy. This is a must-listen if you've ever wondered why your body feels different as you age—or if you've felt frustrated watching men lose weight faster with less effort. You'll walk away with real-world strategies to help your body work for you, not against you. Subscribe for More New episodes every Monday. Subscribe for weekly wellness insight from top health experts and journalists. Stay Connected with Natalie   Website: natalietysdal.com   Instagram: @ntysdal   TikTok: @ntysdal   Facebook: Natalie Tysdal Disclaimer Natalie Tysdal is a health journalist, not a licensed medical professional. This podcast is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Three-quarters of U.S. adults are overweight or obese. But Kevin Hall, a former researcher at the National Institutes of Health and one of the world's top experts in food science, is on a mission to take the shame out of weight gain. He joins Sanjay to talk about his new book, Food Intelligence: The Science of How Food Both Nourishes and Harms Us, and why our many misconceptions about metabolism are distracting us from the real drivers of the obesity crisis.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Send us a textHuman metabolism, primate evolution, and modern health challenges with evolutionary anthropologist Herman Pontzer.Episode Summary: Anthropologist Dr. Herman Pontzer discusses human evolution and metabolism, comparing humans to primates like chimps and gorillas to explain our higher energy use, bigger brains, and longer lives despite trade-offs in reproduction and activity; they discuss dietary shifts from plant-based to hunting-gathering, metabolic adaptations, and modern issues like obesity, where exercise aids health but diet drives weight loss, emphasizing ultra-processed foods' role in overeating and the promise of new drugs like GLP-1 agonists.About the guest: Herman Pontzer, PhD is a professor of evolutionary anthropology and global health at Duke University. He is the author of books like "Burn" and "Adaptable," which explore how bodies adapt to diets, activity, and environments.Discussion Points:Humans burn 20% more daily energy than other primates (controlling for body size), enabling big brains, more babies, and longer lives, but requiring efficient food strategies like hunting and gathering.Unlike apes, humans evolved smaller guts, higher body fat (15-30% vs. apes'

Welcome back to the show. Today we have another Q&A episode, and we discuss whether you should take a probiotic while taking an antibiotic, the concept of a slow metabolism, and whether canned foods are a healthy option to include in your diet. Tune in to the show to hear more, and check out the references below if you want to learn more about the topics discussed on the show. ReferencesProbiotics for Gut Microbiome Diversity Probiotics for the Prevention of Antibiotic-Associated Diarrhea: Meta-AnalysisGenetics of Obesity Energy Expenditure in Obese and Non-ObeseBPA in Canned Foods Nutritional Value of Canned FoodsEnjoying the show or have a questions about a particular topic? Send us a message here. Support the showDo you enjoy the show and want to support it? Here are some ways you can

Are you doing “everything right”… but the scale still won't budge?You're not crazy—and you're definitely not lazy. Your body might just be stuck in fat-storing mode... and no amount of willpower, cardio, or calorie-cutting will fix it.In this episode, I'm breaking down:

Welcome to the Mind Muscle Connection Podcast!In Part 2 of our conversation, I chat again with Christian Rodriguez, this time diving deep into Body Composition, Metabolism and moreWe break down why most popular tools like DEXA scans, metabolic equations, and even wearables often underestimate or mislead, especially for muscular individuals. Christian shares what the latest research is showing, why context matters, and what's actually worth tracking if you want useful data.If you're serious about training, nutrition, and understanding your metabolism beyond just the numbers, don't miss this one.Let's talk about:Visceral fat, location & utility of body fat %Sex differences in body comp researchTotal body water prediction equationsResting metabolic rate prediction equationsEnergy balance, thermogenics & metabolic adaptationChristian's career move to Pennington BiomedicalWhere to find ChristianChristian's Instagram: https://www.instagram.com/__christianrodriguez__/Follow me on Instagram for more information and education:  jeffhoehn_FREE 30 Min Strategy Call: HEREBody Recomp Masterclass: HERENutrition Periodization Masterclass: HEREHow You Can Work With Me?: HERECoaching application: HEREBody Recomp Checklist 2.0: https://chipper-producer-6244.kit.com/26b5c9f94a

In this powerful episode of Accelerated Health with Sara Banta, I'm joined by Philip Pape, host of the top-ranked Wits & Weights podcast and renowned Physique Engineer, to explore one of the biggest health myths out there: that your metabolism is broken.We uncover the real reasons behind low energy, stubborn fat, and sluggish metabolism, and reveal why most people are blaming the wrong things. Philip and I discuss how stress, under-eating, toxic overload, and hormonal dysfunction sabotage your body's natural energy systems—and what you can do to fix it. If you're constantly tired, gaining weight despite eating “healthy,” or feeling like your energy has tanked—this episode is packed with science-backed strategies, real-world tips, and the truth about how to feel vibrant, strong, and unstoppable—without restrictive diets or hours in the gym.

If you struggle with allergies, brain fog, fatigue, or other symptoms you just can't get to the root of, have you ever considered that they might be caused by the AIR in your home?  In this podcast, I'm welcoming Mike Feldstein, Founder of Jaspr, to unpack a topic that touches every breath you take: the quality of your indoor air.  We dive into why high-quality indoor air is a game-changer for your energy, sleep, focus, and long-term health—and why it's often the missing piece in your wellness puzzle.  Mike shares practical, FREE ways you can start improving your indoor air quality today, from simple habits to overlooked sources of indoor pollution you can easily address.  We also dive into why the Jaspr Air Scrubber stands out; how it works, and the powerful benefits it can bring to your home and family's health.  Tune in and get ready to breathe cleaner, feel better, and take control of your home environment with confidence! Mike Feldstein Mike Feldstein is an air quality expert and the founder of Jaspr, providing at-home air scrubbers to make your home a safer place. With a background in wildfire restoration, air quality consulting, and home remediation during some of the biggest natural disasters, Mike started Jaspr to innovate in air science and technology. His goal is to protect air quality and improve human health using the latest air quality science. IN THIS EPISODE How the air quality in your home impacts your health  FREE simple ways to transform your indoor environment in the next 24 hours to make a difference for your health  Helpful air quality enhancements for each room in your home  Ways to test and measure your indoor air quality Jaspr Air scrubbers and the benefit that quality, purified indoor air gives you and your family  About The Kindling Academy: the healthiest school in America  How to get $400 off a Jaspr air scrubber for your home!  QUOTES“I've now seen people have revolutionary health outcomes– no longer snoring, no more allergies, no more asthma attacks, thyroid improving… because if you're sleeping in a sick place, it's very hard to be healthy.” “This is important because cooking is one of the biggest sources of indoor air pollutants in your home. And it doesn't matter if you're using your cast iron pan or your stainless steel with organic oils and grass-fed steak.”  “What Jasper is uniquely designed to do is to be an air scrubber that also looks beautiful and is quiet. Jasper is larger as an air scrubber than most air purifiers, but it moves five times the air of an average little air purifier… it means that it can be really effective even while being silent.” RESOURCES MENTIONED Get a Jaspr Air Purifier for your home HERE and use Discount Code: DRMARIZA for $400 OFF!  Jaspr Instagram Check out the Kindling Academy: The Healthiest School in America  Kindling Academy Instagram Use code ENERGIZED and Get 10% OFF on your first Troscriptions order RELATED EPISODES  Special Episode: Is Toxic Mold Behind Your Hormonal Issues? with Bridgit Danner 659: Brain Fog, Joint Pain, and Aging Skin? The Truth About Zombie Cells and How to Reverse Them with Dr. Greg Kelly  640: Unveiling The Essential Role of Minerals For Cellular Energy And Detoxification with Caroline Alan #92: It Might Be Mold: How Mold Toxicity May Be the Cause of What Ails You with Dr. Ann Shippy

f you're stuck in a cycle of poor sleep, cravings, fatigue, and stubborn weight gain, this episode is for you. I sat down with Jill McRae, co-founder of Inactive Co., to dive into the often-overlooked link between sleep and insulin resistance—especially for midlife women battling hormone chaos. We explore how modern life disrupts your natural sleep-wake rhythms and what it really takes to restore deep, healing rest without pills or complex protocols. Jill shares powerful insights from the Sleep 7 Playbook, a faith-rooted and biology-based approach to resetting your nervous system and supporting your metabolism through rest. Whether you're dealing with adrenal fatigue, high cortisol, or a constant “wired but tired” feeling—this episode will bring clarity and practical tools for transformation. Use code SLEEP25 for 25% off your sleep mask and free shipping!

Your metabolism isn't the villain in your weight loss story. Your approach might be.If you've been convinced that your "slow metabolism" is why you can't lose weight, this episode will change everything. Spoiler alert: metabolic damage is rare, but metabolic confusion from years of yo-yo dieting is common.Here's what's actually happening:·       Why "slow metabolism" is almost never the real problem·       How extreme dieting trains your body to be more efficient at storing fat·       The muscle mass connection that changes everything for women over 35·       How stress, sleep, and inflammation affect your metabolic rate more than geneticsThe solution isn't eating less or exercising more. It's rebuilding trust with your body through consistent, sustainable habits.This episode is perfect for women over 35 who feel like their body has stopped responding to everything that "used to work."Not Another Diet Book: https://www.amazon.com/Not-Another-Diet-Book-learning/dp/B0B45Q4CLH/ref=tmm_pap_swatch_0?_encoding=UTF8&qid=1656499379&sr=8-1Schedule a Session: https://www.heathermaio.com/coaching-options 

In this episode of Thyroid Answers, Dr. Eric Balcavage sits down with functional health coach Anu Simh to explore the critical connection between gut health, thyroid function, and overall metabolism.   What You'll Learn: Why normal TSH doesn't mean optimal thyroid function - and what's really happening at the cellular level  How chronic stress disrupts your gut microbiome and creates a cascade of health issues  The difference between homeostasis and allostatic regulation - and why understanding this changes everything  Why gut protocols often fail long-term (and what's missing from most approaches)  The truth about probiotics, fermented foods, and prebiotic fibers  How ultra-processed foods damage your microbiome - and how quickly you can reverse it  Why GLP-1 medications work but don't address root causes  The behavioral and mindset shifts that make healing sustainable   Key Topics Covered: The mitochondria-microbiome-thyroid connection Why restrictive diets often backfire How to eat for your individual body and microbiome The role of nervous system regulation in gut healing Practical strategies for sustainable behavior change ANU SIMH is a board-certified functional health coach and the founder of 9 Arms of Wellness. She specializes in helping busy women lose weight and maintain their goal weight by focusing on gut health. Her personalized and unique philosophy has successfully guided hundreds of women in achieving and maintaining their goals. Anu is now training other coaches in her methodology. Based in La Jolla, California, Anu sees clients nationwide virtually. Her passion lies in the microbiome; she is also a skilled plant-based chef. Her new book, Flourish From Within, reveals the importance of gut health for overall well-being and includes over 50 plant-based recipes. Anu's guiding principle is to help people get off medications for lifestyle diseases through diet and lifestyle changes. Find her at: ninearmsofwellness.com and @ninearmsofwellness on Instagram.

Are essential oils the missing link to regulating your stress, supporting lymphatic drainage, and releasing stubborn fascia in your body? This episode will have you more aware of your sense of smell than you ever have been! You will learn about the role of essential oils in HPA-axis regulation, facilitating release of trauma, and opening up lymphatic stagnation.    Guest Jodi Cohen of Vibrant Blue Oils shares about her journey with stress and adrenal dysregulation and how essential oils were a game changer. We discuss best practices and use as well as areas of application and how essential oils are different from synthetic fragrances. Learn about how our sense of smell is the most important for survival and how scent training can enhance cognitive function and even mood stability as well as combat cravings and boost metabolism.    Also in this episode:  Keto Reset Masterclass 8/29 Grab your free spot for exclusive savings! More info on our Keto Reset Program - Enrollment opens 8/28! Get a bottle of the Parasympathetic Blend for just $15 + free shipping! ($38.95) Learn more about Vibrant Blue Oils and Jodi Cohen at www.vibrantblueoils.com  Study on fear and smell + how rose can aid in relaxation Research on smell as somatic responder and use in regulating HPA-Axis Link to get my Free 5 day Detox Express Protocol Reset Restore Renew Detox packs to support your cleanse   Sponsor:  Naturally Nourished Supplements Potency, Purity, and Efficacy in a value you can't beat Reset your Metabolism, Restore your Digestion and Renew your Vitality with our Detox Support Packs that provide antioxidants, liver and gallbladder support, sulfur-containing amino acids, and botanicals.  Use SUMMERDETOX to save 15% off Reset Restore Renew Detox Packs In this episode I share how I've been pulsing in 3-5 day mini-Detoxes to stay on track with travel, mindful indulgences, and ebs and flows of schedule. Steal my template below and save 15% on the Reset Restore Renew Detox packs to take at rise, midday, and bed to facilitate phase 1 and phase 2 detoxification pathways.    7am Detox Pack Lemon water, salt Green tea or matcha with Pure collagen   11am Green Smoothie with scoop of Whey Protect   3pm Detox pack 1 Jar of Fond Bone Broth   6pm Lean Green Meal: 5-6oz protein + ⅔ cup of roasted cruciferous veggies    Bed Detox pack  

Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. This week on the Optimal Protein Podcast, I'm thrilled to be joined once again by Dr. Don Layman, one of the world's foremost experts in protein metabolism and amino acid science. In this first part of our two-part conversation, we take a deep dive into the true definition of protein quality, the flaws of current scoring systems, and the metabolic significance of leucine as a primary trigger for muscle protein synthesis. Dr. Layman also introduces the EAA-9 protein quality model, a new way of evaluating protein sources that takes into account the body's exact essential amino acid requirements—moving beyond methods like PDCAAS. Get 20% off on the Tone LUX Crystal Red Light Therapy Mask Ketogenicgirl.com with the code VANESSA We also discuss: Why protein quality should be defined by amino acid content, not nitrogen How leucine “shows up in nature” in exact ratios that muscle recognizes The four key signals muscle responds to: energy, leucine, insulin, and IGF-1 What activates and suppresses mTOR, and why AMPK shuts down MPS in low energy states How protein turnover drives up to 20% of your resting metabolic rate The concept of metabolic prioritization and what happens when your diet lacks adequate EAAs Why the term “protein requirement” is misleading—and why we actually have amino acid requirements Dr. Layman's response to the 100 g of protein study on protein distribution  A preview of what's really happening during fat loss, and how muscle preservation strategies can make or break long-term success This episode is a masterclass in muscle metabolism, protein science, and the tools you need to optimize your nutrition—especially for fat loss and body recomposition.

You've been doing “all the right things” for a few weeks. Eating better, moving your body but the scale hasn't budged. Sound familiar? That's not failure.  That's normal. In this episode, we unpack the uncomfortable truth: healing and real transformation take time, often much longer than we want. You'll hear why quick fixes and crash diets set you up for disappointment, and why slow, steady progress is the only path to sustainable change.  We'll talk about prepping your body before weight loss even begins, what to expect when you start eating more, and why discomfort (yes, including hunger and resistance) is part of the journey. I also share what it took for me to transform over two years and why I still don't believe in a “finish line.”  If you're frustrated with your progress or tempted to give up after a few weeks, this episode will reframe everything. Healing is possible. It just doesn't happen overnight. Time Stamps: (1:17) A Little Sickness In The Pozos Household (3:42) My Healing Journey (5:20) Stock Market Analogy (11:47) The Continuous Process (16:17) Discomfort Is a Feeling (19:22) So Much To Learn Still (20:54) There's No Finish Line---------------------Find Out More Information on Vital Spark Coaching---------------------Follow @vanessagfitness on Instagram for daily fitness tips & motivation. ---------------------Download Our FREE Metabolism-Boosting Workout Program---------------------Join the Women's Metabolism Secrets Facebook Community for 25+ videos teaching you how to start losing fat without hating your life!---------------------Click here to send me a message on Facebook and we'll see how I can help or what best free resources I can share!---------------------Interested in 1-on-1 Coaching with my team of Metabolism & Hormone Experts? Apply Here!---------------------Check out our Youtube Channel!---------------------Enjoyed the podcast? Let us know what you think and leave a 5⭐️ rating and review on iTunes!

Are you stuck in a loop of negative thinking, self-doubt, or frustration with your health journey? You might be unknowingly binge-watching the wrong mental programming—and your brain is queuing up more of the same.In this episode, we dive into a powerful mindset shift using a relatable analogy: Netflix.Just like your favorite streaming service recommends shows based on what you've watched, your brain serves up thoughts based on what you focus on—whether that's lack, failure, or abundance and possibility.You'll learn:- Why your brain keeps defaulting to self-sabotage- How your “mental algorithm” affects consistency, cravings, and confidence- The neuroscience behind focus and how it shapes your health outcomes- Practical strategies to break the binge cycle of negative thoughts and start “streaming” - beliefs that align with who you want to become- How this shift transformed my relationship with food, movement, and self-worth—and how it can do the same for youIf you're ready to stop feeling stuck and start building lasting change from the inside out, this episode is your reset button.TIMESTAMPS:(00:00) - Intro(01:35) - Our brains work the same way as Netflix(04:40) - What you seek, you strengthen (Your RAS)(09:20) - Reframing your thoughts & acknowledging your wins(15:10) - What do you need to start doing instead?(27:11) - Final thoughts + remindersCONNECT WITH ME ONLINE:‣ Fill out our Complimentary Health Assessment to receive customized guidelines for:- how much you should eat

In this episode of The Wisdom of Wellness, Dr. Kayla Lucas sits down with Dr. Vivek Lal—a double board-certified MD and founder of ResBiotic—to unpack the powerful (and often overlooked) role the gut plays in our mood, metabolism, and modern-day disease.

In this episode, Ben shares five underrated but powerful food swaps that can help you lose belly fat, reduce inflammation, and regain energy—especially if you're over 45 and frustrated with weight gain. These simple changes aren't commonly recommended by doctors, but they can drastically improve your health and metabolism. Top 5 Food Swaps: Swap plant milks for organic heavy cream – Avoid seed oils, gums, and sugars. Ditch seed oils for saturated fats – Cut inflammation and support hormones. Replace grains with low-carb veggies – Stabilize blood sugar and reduce cravings. Avoid high-oxalate foods like spinach and almonds – Choose gut-friendly options like arugula and macadamia nuts. Trade pasteurized dairy for goat, sheep, or raw dairy – Improve digestion and skin health. Bonus Topics: How to eat out without consuming bad oils (http://seedoilcard.com) Best supplements to repair damaged cells Why MCT oil is great for coffee, not cooking How quickly you'll see results (hint: day one!) Bodybio PC Oil (needs link) 

Send us a textThe deep connection between sunlight and life, from the scale of the cosmos to the quantum.Episode Summary: Astrophysicist Dr. Robert Fosbury discusses the sun's characteristics as a star, its analogies to living systems via entropy and complexity, and Erwin Schrödinger's insights on life as order-maintaining entities; he explores how near-infrared (NIR) light from the sun penetrates bodies to enhance mitochondrial function and metabolism, critiques modern artificial lighting's health impacts like mitochondrial dysfunction leading to diseases, and advocates returning to natural light environments for better wellness, drawing connections from cosmology to everyday architecture and lifestyle.About the guest: Robert Fosbury, PhD is a is a retired astrophysicist. He spent his career at the European Space Agency, working on Hubble and JWST projects, and now pursues interdisciplinary research linking stellar phenomena to biological processes like light's impact on vision and metabolism.Discussion Points:Stars like the sun maintain low-entropy states by exporting entropy as light, mirroring how life ingests low-entropy food to sustain order and homeostasis.The universe's complexity peaks midway in entropy increase, with stars producing elements that enable biological complexity, evolving toward cognition.Near-infrared light, peaking in solar output at ~1.6 microns due to atmospheric physics, catalyzes mitochondrial ATP production by facilitating electron transport, not via photosynthesis but photo-metabolism.Modern LEDs and windows block near-infrared, contributing to mitochondrial dysfunction, obesity, diabetes, and aging; historical thermal lights like incandescents provided beneficial infrared.Outdoor environments, especially under trees, flood bodies with reflected near-infrared for health, while blue skies act as cold sinks boosting thermodynamic efficiency.Eyes are mitochondria-rich, vulnerable to poor light; therapies using near-infrared slow macular degeneration by improving energy production.Ultra-processed foods are "high-entropy" with no structural order, akin to waste, reducing nutritional value for maintaining bodily order.Practical fixes: Use low-voltage incandescents indoors, prioritize outdoor time, design buildings with infrared-transmitting glass, and light people, not spaces, for energy savings and Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

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Anna learns some surprising sunscreen facts from dermatologist Prof Caitriona Ryan; gets advice on holiday ailments from Dr Suzanne Kelly; and asks Dietician Orla Walsh if it is possible to boost our metabolic rates. Olympian Rob Heffernan is put through his paces in the Supercharged Speed Quiz and there's a taster of Tai Chi.

In this episode, I break down what metabolism ACTUALLY is and if it can 'break'.All myths debunked once and for allEnquire for coaching below https://yxk1v305k46.typeform.com/to/SfP94ewQ

Thinking about starting HRT—or already on it but not seeing results?Here's the truth: HRT isn't a magic fix if your body isn't ready.In this episode, I'm breaking down the 5 things you need to do BEFORE starting hormone therapy so it actually works with your body—not against it.We'll cover gut health, liver detox, blood sugar, stress, and the key labs your doctor probably isn't running.If you want HRT to work the way it's supposed to, this is where you start.TIMESTAMPS:(00:00) - Intro(00:57) - Overview of today's episode(03:30) - Step #1(08:00) - Step #2 (14:37) - Step #3(18:44) - Step #4(23:15) - Step #5(25:50) - Labs to consider before HRT(28:51) - Who should not go on HRT(29:40) - Final thoughts + remindersCONNECT WITH ME ONLINE:‣ Fill out our Complimentary Health Assessment to receive customized guidelines for:- how much you should eat

You're eating healthy. You're working out. You're doing all the things. So why does your body still feel stuck? In this episode, I'm breaking down the #1 thing most women over 40 are missing when it comes to weight loss and metabolism — even if they think they're already doing everything right. We'll talk about why “healthy habits” aren't always helpful in midlife, what's actually happening when your metabolism downshifts, and how to rebuild the trust your body needs to start responding again. This isn't about trying harder.  It's about finally doing what works for this season of life.   When you're ready, here's how I can help you for FREE: (Community + Support) Join my Lori Doddy's Total Wellness community to get research-backed tips, strategies, and free resources to lose weight and manage menopause like  (Lose Fat) Steal my guide with exact 5 Changes I have all clients make in week 1 of working with us, so they lose weight and drop inches even before we put their customized plan in place. Get the guide for free and use it this week!  (Toned Arms) Use these 6 moves to get toned, strong, sexy arms in 15 minutes a day, 2-3 days a week with this guide to Sexy, Strong Arms. (Email List) Sign up to get my tips and strategies plus exclusive content by getting on the LDL Email List!  

Have you ever slashed your calories, skipped meals, or jumped on the latest crash diet—only to feel more exhausted, gain weight, or see your thyroid numbers worsen? You're not alone. In this eye-opening episode, we dive deep into the long-term effects of crash dieting, undereating, and yo-yo dieting on your thyroid and metabolism.We'll unpack how extreme calorie restriction can trigger hormonal imbalances, slow down your metabolism, and even contribute to hypothyroidism -- making it worse! You'll learn how the body adapts to chronic undernourishment, why water fasting and “metabolic confusion” might do more harm than good, and what strategies actually help restore metabolic health after years of dieting.In this episode, you'll learn:How crash dieting can suppress thyroid function and lower your metabolic rateWhy undereating—even "clean eating"—can trigger weight gain and fatigueThe hidden risks of water fasting and extreme carb cycling for people with hypothyroidismWhat metabolic adaptation is, and how to repair itHow to safely rebuild your metabolism and support thyroid recoverySustainable strategies for long-term weight and energy balanceIf you're struggling with weight management, energy crashes, or thyroid symptoms that won't improve—despite eating “healthy”—this conversation is a must-listen. Tune in to discover practical, sustainable steps to rebuild your metabolism, support your thyroid, and ditch the diet cycle for good.LEARN MOREYou can learn more about the topic from Paloma: Can Crash Dieting Cause Hypothyroidism?https://www.palomahealth.com/learn/crash-dieting-hypothyroidism The Effect of Dieting on Your Thyroid Healthhttps://www.youtube.com/live/wfP0IUZX2D8 How to Repair Your Metabolism After Crash and Yo-Yo Dietinghttps://www.palomahealth.com/learn/repair-metabolism-crash-yo-yo-dieting-hypothyroidism How Undereating Can Affect Your Thyroidhttps://www.palomahealth.com/learn/undereating-thyroid How To Fix Metabolic Adaptationhttps://www.palomahealth.com/learn/metabolic-adaptation Is Water Fasting Safe For Hypothyroidism?https://www.palomahealth.com/learn/water-fasting-safe-hypothyroidism Metabolic Confusion, Carb Cycling, and Hypothyroidism Weight Losshttps://www.palomahealth.com/learn/metabolic-confusion-carb-cycling-hypothyroidism-weight-loss ABOUT PALOMA HEALTH ⁠⁠Paloma Health ⁠⁠⁠⁠⁠⁠⁠⁠is an online medical practice focused exclusively on treating hypothyroidism. From online visits with your provider to easy prescription management and lab orders, we create personalized treatment plans for you. Become a member⁠, or try our at-home test kit and experience a whole new level of hypothyroid care. Use code PODCAST to save $30 at checkout.Disclaimer: The $30 discount is only valid for first-time Paloma Health members and test kit users. Coupon must be entered at the time of checkout. Become a Paloma Member:https://www.palomahealth.com/pricing-hypothyroidism Paloma Complete Thyroid Blood Test Kit:https://www.palomahealth.com/home-thyroid-blood-test-kit

Send us a textHow brain synapses work and fuel themselves with fat.Episode Summary: Dr. Timothy Ryan talks about the high energy costs of synapses, the role of mitochondria and glycolysis, and challenge the long-held view that the brain relies solely on glucose by discussing new evidence that neurons burn fats from lipid droplets for fuel, especially during activity. The talk touches on metabolic flexibility, links to epilepsy treatments like ketogenic diets, neurodegenerative diseases, and future research on brain energy sources.About the guest: Timothy Ryan, PhD is a professor of biochemistry at Cornell University. His research focuses on the molecular mechanisms of synaptic transmission, particularly vesicle recycling and the bioenergetics that power neural communication. Discussion Points:Synapses are tiny structures with ~100 vesicles per site (on average), converting electrical signals to chemical ones.Brain tissue is energy-hungry due to trillions of synapses (in humans), relying on local mitochondria (present in only ~half of synapses) and glycolysis.Vesicles use proton pumps and transporters to concentrate neurotransmitters, requiring ATP to maintain gradients.Neurons are metabolically fragile; cutting fuel supply quickly impairs synapses.Dogma held brains don't burn fats, but new work shows neurons form lipid droplets (fat stores) that are invisible because constantly used for energy via beta-oxidation.Silencing neurons builds lipid droplets like resting muscle; activity speeds their breakdown, indicating demand-driven fat use.Inhibiting neuron-specific fat-processing enzymes accumulates droplets and induces torpor (hibernation-like state) in animals, signaling metabolic stress.Ketogenic diets aid epilepsy by shifting to ketones; fats may explain this, with potential ties to aging and neurodegeneration like Alzheimer's.Brain may be a "hybrid" fuel user (glucose + fats), with open questions on fat sources and roles in cognition or disease protection.Related episode:M&M 158: Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino*Not medical advice.Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

Welcome to the Mind Muscle Connection Podcast!In this episode of the Mind Muscle Connection, I sit down with Christian Rodriguez, PhD candidate and body composition researcher at Texas Tech University to talk about Body Composition, Metabolism, and MoreWe dive into his journey starting from losing 75+ pounds and struggling with yo-yo dieting to becoming a respected researcher. He breaks down what most people misunderstand about DEXA, BIA, and consumer-grade tracking devices, and shares what his lab discovered about the accuracy (and inaccuracy) of body composition methods.If you're relying on body fat numbers to track progress or constantly frustrated by inconsistent results, this episode is a must-listen!Let's talk about:Christian RodriguezLosing 75 lbsBody compositionHow accurate are body recomp devicesError rateFollow Christian here: https://www.instagram.com/__christianrodriguez__/Follow me on Instagram for more information and education:  jeffhoehn_FREE 30 Min Strategy Call: HEREBody Recomp Masterclass: HERENutrition Periodization Masterclass: HEREHow You Can Work With Me?: HERECoaching application: HEREBody Recomp Checklist 2.0: https://chipper-producer-6244.kit.com/26b5c9f94a

What is Metabolic Syndrome? 4 THUGS attempting to kill you and erode the quality of your life. These 4 thugs are: blood pressure, blood sugar, cholesterol and your WEIGHT. Here is the kicker – we open the door and invite these 4 thugs into our living room every day through our daily choices. Today we are going to show you how to REVERSE Metabolic Syndrome and discuss a proven 10 week program that is specifically designed to reverse blood sugar and cholesterol issues and guaranteed to drive weight loss.

Fructose has often been labeled a uniquely damaging nutrient, blamed for obesity, diabetes, and other metabolic diseases. But does fructose truly have unique harmful effects or are the risks associated with it related to context and quantity? The episode explores how fructose is metabolized in the body, why it gained a reputation for being problematic, and what the scientific evidence says about fructose in our diets. You will gain insight into why fructose was singled out in the past (e.g., its unique pathway in the liver and lack of insulin response), and how newer studies put those concerns into context. It covers important nuances for practitioners and health-conscious individuals, especially given public confusion and fear around fructose (even in fruit). Guest Information Dr. Scott Harding, Ph.D., is an Associate Professor of Nutritional Biochemistry in the Department of Biochemistry at Memorial University of Newfoundland. His research explores the complex interactions between diet, metabolism, and chronic disease, with a particular emphasis on the metabolic effects of dietary sugars (especially fructose), the role of fats and phytosterols in lipid metabolism, and how public health policies like sugar taxation influence population health outcomes. Timestamps [02:58] Dr. Harding's academic background [08:45] Fructose metabolism in detail [12:51] Fructose in diet and public health [23:07] Current research [29:53] Identifying biomarkers for fructose overconsumption [31:12] Fructose impact on health [40:58] The food matrix [45:10] Personalized nutrition and future research directions [54:06] Key ideas segment (premium-only) Related Resources Subscribe to Sigma Nutrition Premium Join the Sigma email newsletter for free Enroll in the next cohort of our Applied Nutrition Literacy course Related podcast episodes: #476, #468, #155 See Sigma's "Recommended Resources"

In Episode 27, we wrap up our Metabolism series by diving into one of the most testable—and often misunderstood—topics on the MCAT: The Electron Transport Chain (ETC) and Oxidative Phosphorylation.We cover everything you need to know for MCAT success:

In this episode of the Art of Living Well podcast, Liv Hill discusses the concept of nutritional phases, emphasizing the importance of understanding reverse dieting, maintenance, and surplus strategies. She shares her personal experiences and insights on how these phases can lead to better body composition, food freedom, and a healthier relationship with food. Liv encourages listeners to break free from the traditional dieting mentality and explore a more holistic approach to nutrition and health.

Story at-a-glance Linoleic acid (LA), a fat found in vegetable oils, accumulates in your tissues and disrupts mitochondrial function, which drains your energy and slows your metabolism This fat becomes toxic when oxidized, producing harmful byproducts that damage DNA, enzymes, and the machinery your cells need to generate energy Excess LA damages your gut by interfering with colon cell metabolism, harming beneficial microbes, and promoting inflammation linked to insulin resistance and obesity LA's half-life in body fat is about two years, meaning the damage builds up slowly and requires long-term dietary changes to reverse Cutting out vegetable oils, eating gut-repairing whole foods, and switching to stable fats like grass fed butter and tallow are key steps to restoring your metabolic health

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It only took 233 episodes and getting over what I thought would be cricket's if I ever asked my audience to submit questions but I'm so glad we did because we got some incredible questions we're excited to answer on this week's episode! We had over 40 questions submitted and thank you to everyone who sent one in! Today's episode, we will cover 10 questions that were asked frequently or we thought you'd benefit most from hearing about. It's a great blend of health related questions, how we met as a couple, whether or not we've always lived a healthy lifestyle, and a few topics we haven't covered on the show! While we haven't fully decided yet on how we will answer the remaining questions you submitted, rest assured we will and let us know if you enjoyed this style of episode! Time Stamps: (2:54) One Common Trait with Vital Spark Clients(6:34) Bioidentical Progesterone(10:03) How Vanessa and Omar Met(13:45) Inexpensive Biohacks for Happy Hormones(18:32) Build Muscle and Lose Fat While At Maintenance?(21:17) Root Cause of Histamine Issues(26:50) Belly Pooch Weight Gain(29:39) Steady Weight Loss Without Losing Weight?(32:11) Being A Healthy Couple(37:17) GI Solutions---------------------Find Out More Information on Vital Spark Coaching---------------------Follow @vanessagfitness on Instagram for daily fitness tips & motivation. ---------------------Download Our FREE Metabolism-Boosting Workout Program---------------------Join the Women's Metabolism Secrets Facebook Community for 25+ videos teaching you how to start losing fat without hating your life!---------------------Click here to send me a message on Facebook and we'll see how I can help or what best free resources I can share!---------------------Interested in 1-on-1 Coaching with my team of Metabolism & Hormone Experts? Apply Here!---------------------Check out our Youtube Channel!---------------------Enjoyed the podcast? Let us know what you think and leave a 5⭐️ rating and review on iTunes!

Going on HRT hoping it would be the answer to everything?Better sleep, better moods, less brain fog, and finally some weight loss. But instead? You felt worse.More bloated. More anxious. More confused.And yes… More weight gain.In this episode, I'm sharing why things went wrong, what I wish women knew before starting, and why so many women feel worse on hormone therapy when it's supposed to help.If you're on HRT and not feeling better, or wondering if it's right for you… this one's for you.TIMESTAMPS:(00:00) - Intro(01:01) - Overview of HRT part 1(03:12) - Our client's experience with HRT(05:27) - Why can HRT cause negative symptoms and weight gain?(10:44) - What we did with Tina to turn things around(16:34) - What does HRT help with?(17:50) - Final thoughts + remindersCONNECT WITH ME ONLINE:‣ Fill out our Complimentary Health Assessment to receive customized guidelines for:- how much you should eat

Lara Briden is a naturopathic doctor and women's health advocate with over 25 years of clinical experience. Lara has written Period Repair Manual and Hormone Repair Manual. Her latest book, Metabolism Repair For Women,  a compassionate, science based guide to balancing insulin, losing weight and improving health, empowers women to understand and heal their metabolism for lasting health. Lara is also one of my co-founders at MenoClarity. We talk about: - The inspiration for and differences in Lara's books - The importance of understanding metabolic dysfunction - The role of hormones like insulin, estrogen, and testosterone in metabolic health and how they interact during different life stages - The impact of our modern lifestyle - Challenges in balancing blood sugar - Defining metabolic dysfunction and its manifestations - The impact of insulin resistance on women's health - Strategies to restore metabolic balance - The role of circadian rhythm - Practical tips for improving metabolic health  And lots more! If you enjoyed this episode, please subscribe, share it and leave us a 5* review on iTunes or wherever you're listening. Order the ebook or audiobook (narrated by Rachel) versions of Rachel's book, Magnificent Midlife: Transform Your Middle Years, Menopause And Beyond at magnificentmidlife.com/book The paperback can be purchased on Amazon or other online retailers: UK: https://www.amazon.co.uk/Magnificent-Midlife-Transform-Middle-Menopause/dp/173981150X/ US & Canada: https://www.amazon.com/Magnificent-Midlife-Transform-Middle-Menopause/dp/173981150X/ Australia: https://www.amazon.com.au/Magnificent-Midlife-Transform-Middle-Menopause/dp/173981150X/ You can listen to all the other episodes and get the show notes at magnificentmidlife.com/podcast. Recommended by the Sunday Times. Feedspot #9 in 40 Best Midlife Podcasts and #7 in 60 Best Women Over 50 Podcasts You'll find lots of strategies, support, and resources to help make your midlife magnificent at magnificentmidlife.com. Check out Rachel's online Revitalize Experience, a 6-week intensive small group mentoring experience or 1-1 Midlife Mentoring.

In this eye-opening episode of Keeping Abreast, Dr. Jenn sits down with Dr. Tyna Moore for a bold and unfiltered conversation about hormones, metabolism, and the urgent need to rethink modern medicine.Together, they share their personal journeys with plant-based nutrition, the breakdown of conventional medical thinking, and the real-world struggles patients face when trying to get holistic, informed care. Dr. Tyna brings her no-nonsense approach to key topics like GLP-1 medications, peptide therapy, hormone balance, and the power of physiologic (vs. high-dose) dosing.From the limitations of mammograms to the influence of pharmaceutical incentives, this episode explores why critical thinking, muscle mass, and true patient education are the future of healing. If you've ever felt disempowered by a diagnosis—or wondered if there's more to your care—this conversation is your blueprint for reclaiming your health.In This Episode, You Will Learn:Why microdosing GLP-1s may be a safer, smarter optionHow personal nutrition journeys shaped Dr. Jenn and Dr. Tyna's viewsThe overlooked power of muscle, metabolism, and hormonal balanceHow pharmaceutical and insurance incentives influence careWhy informed consent is crucial—and often missingWhat peptides offer in the evolving landscape of holistic healthWhy childhood obesity demands a multi-pronged, educational approachHow to identify truly hormone-literate, patient-centered providersWhat a new model of medicine could look like—and how to get there

In this episode, Ben Azadi reveals 6 truths your doctor won't tell you about fat loss, aging, and metabolic health. Learn why fasting beats grazing, why you should eat fat to burn fat, how your lifestyle—not your genes—determines your health, and why muscle is your ultimate longevity organ. Ben also shares practical tips on protein intake, metabolic blood tests, and the right type of exercise for long-term results.

In this eye-opening episode, Ben Azadi reveals the dangerous truth behind school cafeteria food in the U.S. He breaks down how ultra-processed meals—loaded with seed oils, artificial dyes, sugar, and hormone-disrupting chemicals—are harming kids' brains, metabolism, and long-term health. What You'll Learn: How school food is linked to cancer, obesity, and early puberty Why blood sugar crashes are often mistaken for ADHD The impact of seed oils and additives like Red 40 and BHT How food industry politics shape what kids are fed What parents can do to protect and nourish their children Helpful Resources & Links:

Today, I am excited to welcome you to AMA #13. In this AMA episode, I cover a wide range of topics, including satellite stem cells and the importance of strength training as estrogen and testosterone levels decline. I also answer many questions about hormone replacement therapy, offering general explanations and resources rather than medical advice. Join me for another information-packed AMA session. IN THIS EPISODE, YOU WILL LEARN: Why strength training and sufficient protein intake are essential when your estrogen and testosterone levels drop Importance of HRT for women experiencing mood disorders What reverse dieting is, and how it is more challenging for middle-aged individuals than younger people Benefits of testosterone for muscle building and executive function How low estrogen levels impact the body When should you start taking estrogen? How reduced satellite cell activity during menopause can impair muscle repair and regeneration   The value of progesterone, beyond the uterus What are peptides, and why are they important? How GLP-1s can assist blood flow and immune regulation, and support tissue regeneration Connect with Cynthia Thurlow   Follow on X, Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Research Links: Estrogen Regulates the Satellite Cell Compartment in Females Sarcopenia and Menopause: The Role of Estradiol (2021)/Frontiers in Endocrinology Previous Episodes Mentioned: Ep. 470 Your Midlife Hormone Survival Guide with Dr. Amy Killen Ep. 198 Dispelling Myths about Hormone Replacement Therapy with Dr. Bluming and Carol Tavris Ep. 448 Hair Loss in Women: Causes, Fixes & Expert Tips with Dr. Omer Ibrahim Ep. 463 Midlife Body Masterclass: Strength, Bone, Metabolism with Dr. Vonda Wright, Dr. Stacy Sims, Dr. Shannon Ritchey, and Debra Atkinson Ep. 406 Protein, Creatine, and Training for Menopause and Beyond with Dr. Stacy Sims Ep. 386 Muscle Strength in Menopause: Key Tests & Lifestyle Measures with Dr. Vonda Wright Ep. 456 Why Muscle Matters: Metabolism, Myths & More with Dr. Shannon Ritchey Ep. 321 Muscle, Bone & Joint Health in Menopause with Debra Atkinson Recommended Books: Estrogen Matters by Dr. Avrum Bluming and Dr. Carol Tavris

On this episode of Vitality Radio, Jared launches a brand-new series celebrating time-tested natural remedies that are as relevant today as they were generations ago. “Grandma Was Right” kicks off with an exploration of one of the oldest and most iconic natural tonics: apple cider vinegar (ACV). Jared breaks down what makes ACV so powerful, from its centuries-old use for digestion and energy to its modern applications in blood sugar balance, kidney support, gallbladder health, and even muscle cramp relief. You'll learn about the science behind the “mother,” the difference between capsules, liquids, and gummies, and why vinegar might just be the most underestimated staple in your wellness cabinet. He also shares personal experiences and pro tips for using ACV effectively, especially if you're managing reflux, metabolic issues, or biliary sluggishness. If you've dismissed apple cider vinegar as just another health trend, this episode might change your mind—and your daily routine.Products:Vitality Nutrition Apple Cider Vinegar CapsulesZhou Apple Cider Vinegar Gummiesinner-eco Coconut Vinegar Gummies with ACVRoots & Leaves Fire CiderOld Amish Formulas for Reflux and Leg CrampsDynamic Health Apple Cider Vinegar - in store only Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Today we're cutting through the noise with Dr. Lauren Colenso-Semple - exercise physiologist, researcher, and straight-up myth-buster when it comes to training, fueling, and empowering women.We're talking about:Why most training advice for women is outdated (and flat-out wrong)The truth about protein needs, creatine, and menstrual cycle trainingHow to avoid losing muscle while on GLP-1s (yes, we went there again)Whether weighted vests are a gimmick or a game-changerAnd so much more!This is a no-BS, science-backed conversation for any woman who's tired of being told to eat less, lift light, or shrink to feel worthy.Lauren holds a PhD in Kinesiology and Exercise Physiology. Her research explores sex-based differences in strength and hypertrophy, protein metabolism, and how women actually adapt to training. She's on a mission to help women train smarter, fuel better, and push harder - with real science, not recycled fear tactics.Follow her on Instagram: @drlaurencs1Thank you Cured Nutrition for sponsoring our podcast!We LOVE Cured products and know you will, too! Whether it's popping a Serenity gummy to help you take the edge off after a long day, or taking a Flow gummy to help you crush your workout - Cured has something for you. ⁠⁠⁠Enter our code 'CTC' to receive 20% off your purchase from Cured Nutrition!⁠⁠Follow the pod: @cutthecrapwithbethandmattFollow your hosts:Beth: @bethferacofitnessMatt: @mattlaarfitJoin our Patreon for monthly workouts, challenges, recipes, and to become part of the Cut The Crap Community! This month we are doing a step challenge and are crushing our workouts. Become a member today for exclusive content! ⁠⁠⁠⁠⁠⁠https://www.patreon.com/cutthecrappodcast⁠⁠⁠⁠⁠⁠⁠⁠Visit our website to learn more about us, contact us, inquire about collaborating with us and more: ⁠⁠⁠⁠⁠⁠https://www.cutthecrappod.com/⁠⁠Like this episode? Why not share it with a friend!Send us a DM on Instagram to let us know what you think of this one, and with episode ideas! If we use your comment or suggestion, we'll give you a shoutout on the podcast!

Episode: 1407 A matter of size: scaling laws among living species.  Today, a matter of size.

Send us a textEpisode Summary: Dr. Eugene Chang talks about the microbiome's role as a vital organ, the impacts of antibiotics and Western diets on microbial health, and strategies for restoring a damaged microbiome through diet and fecal microbial transplants. They delve into microbiome dysbiosis, its links to modern diseases, and Chang's research on personalized microbiome interventions.About the guest: Eugene Chang, MD is a physician-scientist and Professor of Medicine at the University of Chicago, specializing in gastroenterology. His research focuses on the gut microbiome as a vital organ influencing metabolic and immune health.Discussion Points:The gut microbiome is a vital organ, acquired early in life, that supports metabolic and immune functions, but can be disrupted by antibiotics, leading to diseases like C. difficile colitis.Western diets, high in saturated fats and low in fiber, contribute to microbiome dysbiosis, linked to modern conditions like inflammatory bowel diseases, obesity, and allergies.Microbiome health is better assessed by functional markers (e.g., short-chain fatty acid production) than taxonomic diversity, as diversity varies widely among healthy individuals.A patient with severe food intolerance due to antibiotic-induced microbiome damage was treated over 50 weeks with a tailored diet, restoring healthy microbiome function.Different dietary fibers (e.g., beans vs. seaweed) are metabolized at varying rates, affecting gut health; fermented foods like kefir can bypass digestion issues.Diet can rapidly reshape the microbiome within 24-48 hours, but severe dysbiosis may require microbial transplants if key microbes are extinct.Chang's research shows a high-fiber, low-fat diet outperforms fecal microbial transplants in restoring microbiome resilience in mice post-antibiotics.Future microbiome medicine may involve personalized “omni microbial transplants” targeting both small and large intestines for comprehensive restoration.Related episode:M&M 203: Metagenomics, Microbiome Transmission, Gut Microbiome in Health & Disease | Nicola Segata*Not medical advice.Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

If you care about longevity, brain optimization, sexual performance, or metabolism, this molecule changes everything. Host Dave Asprey sits down with nitric oxide pioneer Dr. Nathan Bryan to reveal why this overlooked molecule controls your blood flow, mitochondrial energy, neuroplasticity, insulin response, and even your libido. You'll learn how nitric oxide acts as a master switch for human performance and why the medical system has ignored it for decades. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Nathan Bryan is a world-renowned expert in nitric oxide biochemistry with over 20 years of clinical research, multiple patents, and collaborations with Nobel Prize-winning scientists. His groundbreaking work forms the foundation for modern functional medicine protocols targeting blood flow, metabolism, cognitive enhancement, and mitochondrial upgrades. You'll learn: • How nitric oxide drives mitochondria, metabolism, and human performance • Why most nitric oxide supplements fail and how to spot real ones • The critical role nitric oxide plays in brain optimization, libido, and insulin signaling • How poor oral health, statins, and PPIs can kill nitric oxide production • What nitric oxide has to do with sleep optimization, aging, and disease prevention • How to stack nitric oxide with fasting, ketosis, nootropics, red light, and supplements • Why “Smarter Not Harder” starts with nitric oxide fueled upgrades This episode is essential listening for anyone into biohacking, cold therapy, functional medicine, or RFK-style medical freedom. You'll walk away with practical tools to boost nitric oxide naturally, prevent dysfunction, and optimize your biology whether you're on a carnivore diet or just looking for an edge. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Get Nitric Oxide products for 10% off with code ‘Dave': https://bit.ly/Nitric-Oxide-Product SPONSORS: Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • Nathan's Website: https://www.n1o1.com • Nathan's YouTube: https://www.youtube.com/channel/UCtftGy8e0r9DO8ActcyGi4w • Dave Asprey's Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 01:03 Intro • 01:15 Why Medicine Ignores Nitric Oxide • 01:59 What Nitric Oxide Does in the Body • 04:46 How the Body Makes Nitric Oxide • 07:12 Diet's Impact on NO Levels • 13:28 Why Most NO Supplements Fail • 19:32 Personalized Biohacking with NO • 22:33 How Medicine Misses the Mark • 30:40 Oral Health and Nitric Oxide • 31:30 Mouthwash Kills Your Microbiome • 32:28 The Problem with Fluoride • 33:25 Better Toothpaste for NO • 33:49 NO's Role in Energy and Healing • 34:17 Blood Pressure and NO • 35:29 NO and Sexual Performance • 37:09 NO and COVID Recovery • 40:50 Brain Fog and NO Deficiency • 49:01 Carnivore, Sugar, and NO • 50:11 Why You Still Need NO Supplements • 54:19 Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ever wondered if sitting in a sauna could actually help you burn fat—especially during perimenopause or menopause?You're not alone.In this episode, we're diving into the surprising science behind how saunas can support fat loss especially in women over 40—and why it's so much more than just sweating out water weight.

In this episode of Iron Culture, Dr. Eric Trexler and Dr. Lauren Colenso-Semple discuss science related to attractiveness, coolness, and personality type. They explore scientific studies on the factors associated with perceived attractiveness and "coolness," discussing body fat percentages and societal perceptions. The conversation shifts to how personality traits appear to predict workout preferences and engagement in fitness, then they debate the importance of matching exercise to individual characteristics. Time stamps: 00:00 Introduction to Iron Culture and Guests 5:57 The Science of (Male) Attractiveness 10:39 Evolutionary Underpinnings of Male Attractiveness 13:53 Distorted Perceptions of Attractiveness (In the Fitness World) 20:10 The Irony of Pursuing Attractiveness 22:22 Body-Fat and Optimized Health 24:18 Surprising Article Feedback 28:50 Unrealistic Body Standards and Gender Perceptions 32:49 Achieving the Outcome Versus Doing Hard Things 35:07 Attractiveness is More Than Body Shape/Size 37:48 The Science of Being Cool 47:19 Matching Exercise To Personality Types References: Xia F, Sauciuvenaite J, Bissland R, Hambly C, Starr-Vaanholt L, Faries MD, et al. The relationship between body fatness and physical attractiveness in males. Personality and Individual Differences. 2025 Sep 1;243:113240. de Jager S, Coetzee N, Coetzee V. Facial Adiposity, Attractiveness, and Health: A Review. Front Psychol. 2018 Dec 21;9:2562. Brierley ME, Brooks KR, Mond J, Stevenson RJ, Stephen ID. The Body and the Beautiful: Health, Attractiveness and Body Composition in Men's and Women's Bodies. PLoS One. 2016;11(6):e0156722. Sorokowski P, Kościński K, Sorokowska A, Huanca T. Preference for Women's Body Mass and Waist-to-Hip Ratio in Tsimane' Men of the Bolivian Amazon: Biological and Cultural Determinants. PLoS One. 2014 Aug 22;9(8):e105468. Tovée MJ, Cornelissen PL. Female and male perceptions of female physical attractiveness in front-view and profile. Br J Psychol. 2001 May;92(Pt 2):391–402. Jayedi A, Khan TA, Aune D, Emadi A, Shab-Bidar S. Body fat and risk of all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies. Int J Obes (Lond). 2022 Sep;46(9):1573–81. Hu J, Chen X, Yang J, Giovannucci E, Lee DH, Luo W, et al. Association between fat mass and mortality: analysis of Mendelian randomization and lifestyle modification. Metabolism. 2022 Nov;136:155307. Ramlau-Hansen CH, Thulstrup AM, Nohr EA, Bonde JP, Sørensen TIA, Olsen J. Subfecundity in overweight and obese couples. Hum Reprod. 2007 Jun;22(6):1634–7. Wei S, Schmidt MD, Dwyer T, Norman RJ, Venn AJ. Obesity and menstrual irregularity: associations with SHBG, testosterone, and insulin. Obesity (Silver Spring). 2009 May;17(5):1070–6. Liu Y, Hu X, Xiong M, Li J, Jiang X, Wan Y, et al. Association of BMI with erectile dysfunction: A cross-sectional study of men from an andrology clinic. Front Endocrinol (Lausanne). 2023;14:1135024. https://psycnet.apa.org/doiLanding?doi=10.1037%2Fxge0001799 https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2025.1587472/full