This Week in Virology

In his weekly clinical update, Dr. Griffin and Vincent Racaniello protest Vinjay Prasad, head of CBER FDA Nov memo stating administration of the COVID-19 vaccine resulted in 10 children's deaths, but are cautiously delighted by the December memo from those in CBER who dispute this data-less claim, how in 31 states pertussis vaccination rates have declined before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, of clinical outcomes of oseltamivir versus baloxavir for treating influenza infection, number deaths associated with COVID-19 hospitalizations and disease associated economic burden, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how the German government is committed to research into long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Industry laments Prasad vaccine memo (Politico) Scoop: FDA vaccine chief's memo cited 10 pediatric Covid-19 vaccine deaths—but the agency's own analysis found 0–7 (Inside Medicine) Whooping cough cases soar as vaccination rates drop (NBC News) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Hundreds quarantined as South Carolina measles outbreak accelerates (Washington Post) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) In call with clinicians, CDC recommends flu vaccines widely (CIDRAP) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) Comparison of clinical outcomes of oseltamivir versus baloxavir in outpatients with influenza: a retrospective cohort analysis (International Journal of Infectious Diseases) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Effectiveness of 2024–2025 COVID-19 Vaccines in Children in the United States — VISION, August 29, 2024–September 2, 2025 (CDC:MMWR) Mortality following recovery from COVID-19 hospitalization: A long-term cohort study (International Journal of Infectious Diseases) COVID hospitalization tied to 69% higher risk of death for up to 2 years (CIDRAP) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Comparison of work productivity losses in the United States among employees with COVID-19 at high-risk of severe disease who were untreated or treated with nirmatrelvir/ritonavir (Journal of Medical Economics) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long-COVID research just got a big funding boost: will it find new treatments?(Nature) Reaching out to US house representative Letters read on TWiV 1280 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews considerations and perspectives on phage therapy, and the Nobel Prize-winning discovery of hepatitis b virus. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator ASV 2026 WHO global expert committee: no link between vaccines and autism (News-Medical) Considerations on phage therapy (Nat Comm) What is TATFAR? (CDC) History of phage therapy (one, two) JAMA Viruses that (can) make you well (TWiV 1153) The InVinceable TWiV (TWiV 145) Blumberg Nobel Lecture 1976 Particles associated with Australia antigen in patients (Nature) HBV vaccination remains vital for saving lives (Hep B Foundation) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Rich – Scientist's cat, again, helps discover new virus Alan – Wormtalk video on politicization of screwworm spread Jolene – Arrowsmith by Sinclair Lewis Vincent – Scoop: FDA vaccine chief's memo cited 10 pediatric Covid-19 vaccine deaths—but the agency's own analysis found 0–7 Listener Picks David – Astronomy Picture of the Day Eric – Jesse Welles (United Health) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the rise in norovirus infections, contamination of infant formula and botulism outbreak, confusion and response to the CDC's ACIP decision to reverse the recommendation for a birth dose of the hepatis B virus vaccine and how states in the Northwest and Northeast are responding as well as some insurance companies, then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, South Carolina's imposed quarantine of individuals due to their accelerated measles outbreak, neurotropism of H1N1, benefits of the RSV and COVID vaccines, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Norovirus season! (Wastewater Scan) Outbreak Investigation of Infant Botulism: Infant Formula (November 2025) (FDA: Foodborne illnesses) Botulism outbreak sickens more than 50 babies and expands to all ByHeart products (AP News) CDC advisers drop decades-old universal hepatitis B birth dose recommendation, suggest blood testing after 1 dose (CIDRAP) Health and Economic Benefits of Routine Childhood Immunizations in the Era of the Vaccines for Children Program — United States, 1994–2023 (CDC: MMWR) Universal Hepatitis B vaccination at birth: safety, effectiveness and public health impact (CIDRAP) Recommended Child and Adolescent Immunization Schedule for Ages 18 years or younger (American Academy of Pediatrics) West Coast health experts reject RFK Jr. panel, say hepatitis B vaccines at birth should continue (The Oregonian) Statement from the Northeast Public Health Collaborative In Response to ACIP's Hepatitis B Vote (NJ.Gov Health) Governors Denounce ACIP Recommendation on Hepatitis B Vaccination, Reaffirm Commitment to Strong, Evidence-Based Childhood Vaccination Programs (Governors Public Health Alliance) Blue Cross and Blue Shield Companies Statement on Vaccines (Blue Cross Blue Shield) AHIPStatement on Vaccine Coverage (AHIP) Pediatricians reject CDC advisers' guidance, plan to continue vaccinating all newborns against hepatitis B (CIDRAP) Survey: Social media on par with CDC as trusted vaccine source (Healio) FDA to investigate whether adult deaths linked to COVID vaccine (Washington Post) Exclusive: US FDA launches fresh safety scrutiny of approved RSV therapies for infants (Reuters) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease) Contemporary highly pathogenic avian influenza (H5N1) viruses retain neurotropism in human cerebral organoids (OFID) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Indiana, cases of New World screwworm in Mexico, rising US flu activity (CIDRAP) Mexico reports 92 cases of myiasis in humans caused by screwworm (Expreso.press) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Hundreds quarantined as South Carolina measles outbreak accelerates (Washington Post) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Types of Influenza Viruses (CDC: Influenza (flu)) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Intensive Care Unit Stay and Mechanical Ventilation Among Adults with Respiratory Syncytial Virus-Related Hospitalization by Age and Comorbidity Status (Infectious Diseases and Therapy) Cardiovascular Events 1 Year After Respiratory Syncytial Virus Infection in Adults (JAMA: Open Network) Long-Term Illness in Adults Hospitalized for Respiratory Syncytial Virus Disease, United States, February 2022–September 2023 (CDC: Emerging Infectious Diseases) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Effectiveness of the maternal RSVpreF vaccine against severe disease in infants in Scotland, UK: a national, population-based case–control study and cohort analysis (LANCET: Infectious Diseases) Effectiveness of Nirsevimab in Preventing Respiratory Syncytial Virus-related Burden: A Test-negative Case-control Study in Infants With Bronchiolitis in Lombardy Region, Italy (The Pediatric Infectious Disease Journal) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Maternal and Neonatal Outcomes After Respiratory Syncytial Virus Prefusion F Protein Vaccination During Pregnancy (Obstetrics & Gynecology) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) COVID-19 mRNA Vaccination and 4-Year All-Cause Mortality Among Adults Aged 18 to 59 Years in France (JAMA: Open Network) Two-year prognosis of mRNA vaccine-related myocarditis compared with historical conventional myocarditis: a population-based cohort study (CMI: Clinical Microbiology and Infection) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1278 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Infectious diseases physician Jake Scott returns to TWiV to discuss the dangerous anti-vaccine policies being established in the US and what RFK Jr. and his associates get wrong. Hosts: Vincent Racaniello, Rich Condit, and Angela Mingarelli Guest: Jake Scott Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Vaccine RCT spreadsheet (CIDRAP) What RFK Jr gets wrong about vaccines (Conversation) RFK Jr's case against mRNA vaccines collapses (STAT) Too many kids' vaccines? Think again (STAT) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Angela Palmer, science meets art (one, two) Rich – TWiV Special: A Shot of Hep B with Thomas Tu; TWiV Special: A shot of HepB with Chari Cohen Vincent – TSA is checking senior's phones for these 5 apps Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the positive side effect of the shingles vaccine on dementia outcomes and how one dose of the HPV vaccine is non-inferior to two doses, but are dismayed about the FDA's secrecy around the inflammatory statement that the COVID-19 vaccine is linked to the death of 10 children. Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, effectiveness of maternal administration of the RVS vaccine or the COVID vaccine for neonates, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how celiac plexus blocks improves gastrointestinal long COVID symptoms, brain alterations and neurodegenerative processes in long COVID cognitive impairment and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode The effect of shingles vaccination at different stages of the dementia disease course (Cell) FDA links 10 children's deaths to COVID-19 vaccines. Doctors want proof (ABC News) Subject: Deaths in children due to COVID-19 vaccines and CBER's path forward Dear Team CBER,(Washington Post) Noninferiority of One HPV Vaccine Dose to Two Doses(NEJM) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease) Washington state resident believed to be the first to die from a rare strain of bird flu (AP News) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Types of Influenza Viruses (CDC: Influenza (flu)) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Maternal and Neonatal Outcomes After Respiratory Syncytial Virus Prefusion F Protein Vaccination During Pregnancy (Obstetrics & Gynecology) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Effectiveness of COVID-19 vaccines against post-COVID-19 condition/long COVID: systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) SARS-CoV-2Infection Versus Vaccination During Pregnancy: Implications for Placental Antibody Transfer (The Pediatric Infectious Disease Journal) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Case Report: Celiac plexus block improves gastrointestinal Long COVID symptoms (Frontiers Neuroscience) Distinct brain alterations and neurodegenerative processes in cognitive impairment associated with post-acute sequelae of COVID-19 (Nature Communications) Reaching out to US house representative Letters read on TWiV 1276 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explains the Nobel Prize-winning discovery of pre-mRNA splicing, and engineering bacteriophage to deliver proteins to the human intestine. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator Spliced segments of adenovirus mRNA (PNAS) An amazing sequence in adenovirus mRNA (Cell) Nobel Prize for mRNA splicing (Nobel) A predominant undecanucleotide in adenovirus late mRNAs (Cell) Splicing RNA with Phillip A. Sharp (ASM) Protein production in the gut by engineered phage (Nat Biotech) Engineered phage T4 (Curr Op Virol) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Can You Identify These Lines from Classic SciFi Novels? Kathy – Saturday Morning Physics, Photograph 51 and JCE article Rich – Wikipedia:Wiki Science Competition 2025 in the United States Jolene – Data visualization workshop Vincent – Transformer: The Deep Chemistry of Life and Death by Nick Lane Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello wish everyone a Happy Thanksgiving and then decry appointment of the Louisiana State surgeon general as deputy chief of the CDC, the 3 children's deaths during this fall's pertussis outbreak, the Marburg virus outbreak in Ethiopia, results of the phase 1 safety trial for the novel poliovirus vaccines nOPV1 and nOPV3, and the first human death from H5N5 influenza virus infection in the US this fall, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, effectiveness of the cell or egg based flu or the mRNA vaccines, immunogenicity and efficacy of updated COVID-19 vaccines, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, immune and cognitive dysfunction during long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Anti-science Movement: Deputy director of CDC (X:Louisiana Office of the Surgeon General) CDC's new deputy director is vocal critic of vaccines, advocated for ivermectin (CIDRAP) Whooping cough cases on the rise in Texas (FOX4: KDFW) Third infant in Kentucky dies of whooping cough as national cases stay high for second year in a row (CIDRAP) More than 25,000 whooping cough cases reported this year as Kentucky records 3rd infant death (ABC News) Vaccination Coverage and Exemptions among Kindergartners (CDC: SchoolVaxView) Effects of human papillomavirus (HPV) vaccination programmes on community rates of HPV‐related disease and harms from vaccination (Cochrane Library) Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease) Safety and immunogenicity of novel live attenuated type 1 and type 3 oral poliomyelitis vaccines in healthy adults in the USA: a first-in-human, observer-masked, multicentre, phase 1 randomised controlled trial (LANCET: Infectious Diseases) Washington state resident believed to be the first to die from a rare strain of bird flu (AP News) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Superior Effectiveness and Estimated Public Health Impact of Cell- Versus Egg-Based Influenza Vaccines in Children and Adults During the US 2023–2024 Season (Infectious Diseases and Therapy) Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine(NEJM) ACIP Recommendations Summary (CDC: Influenza) Types of Influenza Viruses (CDC: Influenza (flu)) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Estimating Risk of Guillain-Barré Syndrome in US Medicare-Enrolled Older Adults Following Medically Attended Respiratory Syncytial Virus Disease (CID) FDA Requires Guillain-Barré Syndrome (GBS) Warning in the Prescribing Information for RSV Vaccines Abrysvo and Arexvy: FDA Safety Communication (FDA) Brag Sets Off a Chain Reaction — Dr. Oz Takes the Bait, But Fumbles the Math, and Starts Unraveling Mid-Interview (Atlanta BlackStar) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Effectiveness of the BNT162b2 and mRNA-1273 JN.1-adapted vaccines against COVID-19-associated hospitalisation and death: a Danish, nationwide, register-based, cohort study (LANCET: Infectious Diseases) Immunogenicity of JN.1- and KP.2-Encoding mRNA COVID-19 Vaccines Against JN.1 Subvariants in Adult Participants (OFID) SARS-CoV-2 vaccination and myositis in Norway and Sweden (Rheumatology) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Digitally Assessed Long COVID Symptomatology Is Associated With Lymphocyte Mitochondrial Dysfunction and Altered Immune Potential (OFID) Evaluation of Interventions for Cognitive Symptoms in Long COVID (JAMA Neurology) Reaching out to US house representative Letters read on TWiV 1274 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explains the 1953 paper by Watson & Crick proposing a structure for DNA, and the role of Epstein-Barr virus in triggering the autoimmune disease systemic lupus erythematosus. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator CDC revives debunked 'link' between childhood vaccines and autism (npr) A structure for deoxyribose nucleic acid (Nature pdf) Three Papers, Three Lessons (Am J Resp Crit Care Med) Discovery of Double Helix (Crick Papers) Jim Watson was blinded by DNA (NY Times) What Rosalind Franklin contributed (Nature) EBV reprograms autoreactive B-cells in lupus (Sci Transl Med) EBV and the making of lupus (Sci Transl Med) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Virus snowflakes Kathy – When "Physic(k)s Lost Its 'k' and other Language Quarks Vincent – The Peripheral by William Gibson Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed by the changes on CDC vaccine website positively stating the link between autism and vaccination, the finding of wild type poliovirus 1 in Germany, Marburg virus in Ethiopia, decimation of the elephant breeding colony by H5N1 and the first human case of H5N5 influenza virus infection before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, antibody escape by seasonal flu viruses, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, if resistance exercise aids in recovery from long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Autism and Vaccines (CDC: Vaccine Safety) A new road to eradication- WPV 1 in Germany from Afghanistan (Reuters) Ethiopia confirms first outbreak of Marburg virus disease (WHO: Ethiopia) Highly Pathogenic Avian Influenza Viruses (HPAIV) Associated with Major Southern Elephant Seal Decline at South Georgia (Communications Biology) Avian flu has decimated world's largest breeding colony of southern elephant seals (CIDRAP) Washington resident is infected with a different type of bird flu (AP News) Pelagic Seabirds (OceanAminals) That sounds far away: Multiple transatlantic incursions of highly pathogenic avian influenza clade 2.3.4.4b A(H5N5) virus into North America and spillover to mammals (Cell Reports) Regional voices, different choices: Parents' and caregivers' HPV vaccine attitudes in the northeast and Southeast United States (Vaccine) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Emergence of seasonal influenza A(H3N2) variants with immune escape potential warrants enhanced molecular and epidemiological surveillance for the 2025–2026 season (University of Toronto Press) Types of Influenza Viruses (CDC: Influenza (flu)) With an absent CDC and mismatched 'subclade K' flu strain, experts face upcoming season with uncertainty (CIDRAP) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Long-term impact of nirsevimab on prevention of respiratory syncytial virus infection using a real-word global database (Journal of Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Estimating Risk of Guillain-Barré Syndrome in US Medicare-Enrolled Older Adults Following Medically Attended Respiratory Syncytial Virus Disease (CID) FDA Requires Guillain-Barré Syndrome (GBS) Warning in the Prescribing Information for RSV Vaccines Abrysvo and Arexvy: FDA Safety Communication (FDA) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) COVID-19 vaccination is associated with reduced complications in pediatric patients with atopic dermatitis (Annals of Allergy, Asthma and Immunology) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) Risk mitigation of shared room ventilation and filtration on SARS-CoV-2 transmission: a multicenter test-negative study (Infection Control and Hospital Epidemiology) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Resistance Exercise Therapy After COVID-19 Infection(JAMA Open Network) Reaching out to US house representative Letters read on TWiV 1272 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Vincent visits Virginia Tech for the CeZAP Symposium and speaks with XJ Meng and Kylene Kehn-Hall about their research on hepatitis E virus and Rift Valley fever virus.   Host: Vincent Racaniello Guests: XJ Meng and Kylene Kehn-Hall Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator Hepatitis E virus (Curr Op Micro) Rift Valley fever virus NSs and autophagy (PLoS Path) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello record from the ASTMH meeting in Toronto and discuss continuing avian flu outbreaks, the continued global measles outbreak, the effectiveness of high and low doses of the influenza vaccine before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, children hospitalizations following COVID-19 and influenza vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Five new avian flu outbreaks confirmed in ducks, turkeys in 3 US states (CIDRAP) Confirmation of highly pathogenic Avian Influenza in Commercial and Backyard flocks (USDA: Animal and Plant Health Inspection Service) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Effectiveness of high-dose influenza vaccine against hospitalisations in older adults (FLUNITY-HD) (LANCET) Relative effectiveness of the high-dose versus standard-dose influenza vaccines for the prevention of laboratory-confirmed influenza among Italian older adults during three recent seasons (International Journal of Infectious Diseases) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Long-term impact of nirsevimab on prevention of respiratory syncytial virus infection using a real-word global database (Journal of Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) COVID-19 and influenza deaths in Australian children 2018-2023: a national case analysis (Journal of Pediatric Infectious Diseases Society) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1270 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews the passing of James D. Watson, the research that showed human papillomaviruses to be present in genital and laryngeal papillomas and in some cervical cancers, and influenza virus infection, shedding and symptoms in a human challenge study. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator James D. Watson dies (NY Times) Russian translation of TWiV 1024 (Medium) Canada's new budget aims to lure US researchers (Science) Bird flu surging and spreading while US agencies are asleep (npr) US slashed WHO budget, now flu surveillance is suffering globally (npr) HPV sequences in papillomas and cervical cancers (PNAS) zur Hausen Nobel Prize 2008 (Nobel) Vincent interviews zur Hausen (YouTube) Influenza virus infection, shedding, and disease in humans (J Virol) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Pandemic board game Rich – Whiskey Fungus Fed by Jack Daniel's Encrusts a Tennessee Town Alan – Rats can snatch bats out of the air and eat them Vincent – 7 basic science discoveries that changed the world Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses the link between in utero SARS-CoV-2 infection and poor neurodevelopment outcomes, the use of an mRNA vaccine as an anti-cancer therapy, why one should receive the HPV vaccine, asymptomatic H5N1 isolations in humans, and H5N1 on turkey farms, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how two vaccinated physicians became infected with measles, effective of COVID-19 vaccine for children, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how a specific antibody type may associate with recovery from long COVID, if use of a probiotic is helpful to treat mild COVID-19, if vaccination helps prevent long in adolescents and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero (Obstetrics & Gynecology) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1267: A cancer vaccine and an mpox treatment (microbeTV: TWiV1267) Cancers Caused by HPV (CDC: Human papillomavirus (HPV)) Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of National Cancer Institute) Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine (Viruses) ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP)) HPV Vaccination Recommendation (CDC: Vaccines & Immunizations) Asymptomatic Human Infections With Avian Influenza A(H5N1) Virus Confirmed by Molecular and Serologic Testing (JAMA: OPEN Network) Review: Human H5N1 avian flu cases can be asymptomatic, and the virus likely spreads among people (CIDRAP) Avian flu strikes turkey farms in Dakotas, large egg facility in California (CIDRAP) Another Doctor at Ichilov Contracts Measles After Treating Unvaccinated Child (gov.il) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England (LANCET: Child & Adolescent Health) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Real-World Effectiveness of Nirmatrelvir-Ritonavir in Preventing Coronavirus Disease 2019–Associated Hospitalization (CID) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID SARS-CoV-2 spike-specific IgG4 class switching associates with clinical recovery in Long COVID (Journal of Infection) Efficacy of Lactococcus lactis Strain Plasma in Patients with Mild COVID-19 (Infectious Diseases and Therapy) Preventive effect of vaccination on long COVID in adolescents with SARS-CoV-2 infection (Vaccine) Reaching out to US house representative Letters read on TWiV 1268 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV discusses the impact of vaccinating with Gardasil-9 adult women who are human papillomavirus positive or with confirmed squamous intraepithelial lesions, and human monoclonal antibodies that target the monkeypox virus A35 protein which protect against lethal disease. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator Long tailed macaques are now officially endangered (Science) Iceland now has mosquitoes (npr) Impact of Gardasil-9 on adult women who are HPV+ or SIL+ (Viruses) Human mAbs that protect against mpox disease (Cell) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Civet coffee: The real chemistry behind this bizarre luxury drink Kathy – Astronomy photographer of the year awards Rich – Katherine Swan Ginsburg Humanism in Medicine Program Alan – Parasitic worms can use static electricity to latch onto flies midair Vincent – How to get the best night's sleep: what the science says Listener Pick Bradon – Elevated Access Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello ponder the nomination of Casey Means for Surgeon General by President Trump, how mRNA vaccines may enhance effectiveness of check point inhibitor cancer therapies, if viral infection associates with cardiac disease, H5N1 isolation from backyard birds and turkey farms, and the effectiveness of the COVID-19, RSV and influenza vaccines before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, if revaccination with the mRNA RSV vaccine is effective, how effective today's COVID-19 vaccine is for protection against severe disease following infection with current viral variants, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV: TWiV 1265) Viral Infections and Risk of Cardiovascular Disease (Journal of the American Heart Association) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP) Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 (NEJM) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles vaccine recommendations from NYP (jpg) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: Cliff notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Safety, Tolerability, and Immunogenicity of Revaccination With mRNA-1345, an mRNA Vaccine Against RSV, Administered 12 Months Following a Primary Dose in Adults Aged ≥50 Years (CID) Vaccine effectiveness of a bivalent respiratory syncytial virus (RSV) pre-F vaccine against RSV-associated hospital admission among adults aged 75–79 years in England (LANCET: Infectious Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans (NEJM) Durability of 2024-2025 COVID-19 Vaccines Against JN.1 Subvariants (JAMA: Internal Medicine) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1266 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explains studies showing that SARS-CoV-2 mRNA vaccines improve life span of cancer patients on checkpoint immunotherapy, and broad immunity conferred by a vaccine central in A(H5) influenza antigenic space. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Immune 100 live at the Incubator SARS-CoV-2 mRNA vaccines sensitize tumors to checkpoint immunotherapy (Nature) People with some cancers live longer after mRNA vaccines (Nature) Immune checkpoint inhibitors (NCI) Broad immunity from influenza H5 vaccine (Nature) Derek Smith on antigenic cartography (TWiV 99 at 2:53) Letters read on TWiV 1265 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Kathy – Permethrin-treated baby wraps for malaria prevention and Phil Sharp and the Biotech Revolution Rich – Lydia Fairchild; Tetragametic Chimerism (NEJM) Alan – Warning Signs Vincent – radio.garden thanks to Kim! Listener Pick Jamie – SkyCards by Flightradar24 Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are distressed by the continuing government shutdown, first locally acquired chikungunya virus infection, President Trump's suggestion for removing aluminum from vaccines, H5N1 isolation from backyard birds and turkey farms, and the suggestion of establishing an alternative to the CDC's MMWR and asymptomatic measles infections before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the quarantining in the US due to measles, access to anti-influenza antiviral, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, if colchicine is effective for long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode New York health officials confirm state's first locally acquired case of chikungunya virus (AP News) Trump Rattles Vaccine Experts Over Aluminum (NY Times) Aluminum-Adsorbed Vaccines and Chronic Diseases in Childhood (Annals of Internal Medicine) Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Jeffrey Lee McLean (California.No) California mpox cases raise concerns. But health officials say the risk remains low (AP News) ‘Alternative' to CDC's Flagship Journal in the Works (MEDPAGE TODAY) Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID) Frustration grows amid measles outbreak quarantines across several states (NBC News) More Than 100 Cases of Measles Reported in Utah and Arizona (NY Times) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine recommendations from NYP (jpg) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) American Academy of Pediatrics Flu and Children (CDC: Influenza (flu)) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) Roche to sell flu pill for $50 to cash-paying US patients (Reuters) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Efficacy and safety of respiratory syncytial virus vaccines (Cochrane Library) Estimated Vaccine Effectiveness for Respiratory Syncytial Virus–Related Acute Respiratory Illness in Older Adults (CID) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Effectiveness of Colchicine for the Treatment of Long COVID(JAMA Internal Medicine) Reaching out to US house representative Letters read on TWiV 1264 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews continuing US measles outbreak, host and genetic variations that regulate antibody responses to hepatitis C virus, and varicella-zoster reactivation and the risk of dementia. Hosts: Vincent Racaniello, Alan Dove, Brianne Barker, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Mass firings at CDC (Time) Measles cases continue to climb in US (NPR) Immune 100 at The Incubator (Eventbrite) Viral and host variations modulate antibody responses against HCV (Cell Rep) VZV reactivation and risk of dementia (Nature Med) Taking a shot at dementia (TWiV 1207) Demented and crass (TWiV 1249) Letters read on TWiV 1263 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – ‘Am I redundant?': how AI changed my career in bioinformatics Brianne – OpenSpace and their YouTube Channel Alan – Coral City Camera – live view of a reef in Biscayne Bay, FL (and NPR story on it). Vincent – Neck pain relief exercises with Dr. Adam Fields Listener Pick Greg – AI: What could go wrong? and An AI System With Detailed Diagnostic Reasoning Makes Its Case Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are dismayed by the government shutdown, the firings at the CDC including EIS agents, H5N1 isolation from backyard birds and its stability in raw milk and cheese, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the quarantining of college students in the US due to measles, Japan's declaration of a national influenza outbreak, effectiveness of the influenza and COVID vaccines, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, results from PLATCOV studies- still no antiviral activity attributed to ivermectin, where to go for answers to your long COVID questions, long COVID in pediatrics, patient reported outcomes from the STOP-PASC clinical trial, contacting your federal government representative to stop the assault on science and biomedical research and the listener reminder that measles vaccine in those with interferonopathy may result in severe adverse affects. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Trump Administration Lays Off Dozens of C.D.C. Officials (NY Times) CDC walks back hundreds of firings as US shutdown persists (Yahoo News/ Reuters) CDC battered by government shutdown firings, while some are rescinded (STAT 10) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Flurry of H5N1 activity noted in commercial poultry, wild birds(CIDRAP) H5N1 influenza virus stability and transmission risk in raw milk and cheese(Nature Medicine) Hundreds of U.S. students quarantined amid measles outbreaks (NBC News) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Japan sees early flu activity, with school closures(CIDRAP) Japan Declares Nationwide Flu Outbreak Following Early Surge in Cases (insightscare) ACIP Recommendations Summary (CDC: Influenza) American Academy of Pediatrics Flu and Children (CDC: Influenza (flu)) Effectiveness of influenza vaccination to prevent severe disease (CMI: Clinical Microbiology and Infection) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Efficacy and safety of respiratory syncytial virus vaccines (Cochrane Library) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Effectiveness of NVX-CoV2373 and BNT162b2 COVID-19 Vaccination in South Korean Adolescents (The Pediatric Infectious Disease Journal) Trump gets Covid vaccine and flu shot during second checkup of the year (NBC News) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Pharmacometrics of high-dose ivermectin in early COVID-19 from an open label, randomized, controlled adaptive platform trial (PLATCOV)(eLife) Antiviral efficacy of oral ensitrelvir versus oral ritonavir-boosted nirmatrelvir in COVID-19 (PLATCOV) (LANCET: Infectious Diseases) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection (JAMA Internal Medicine) Longitudinal patient-reported outcome trajectories in Long COVID: Findings from the STOP-PASC Clinical Trial (OFID) Reaching out to US house representative Severe Adverse Reaction to Measles Vaccine Due to Homozygous Mutation in the IFNAR2 Gene: A Case Report and Literature Review (Journal of Clinical Immunology) Letters read on TWiV 1262 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV covers a MacArthur Award for Jason McLellan, 2025 Nobel Prizes in Physiology or Medicine, first treatment for Huntington's Disease, structure of an archael dsDNA virus from head to tail, and discovery of a Legionella phage that explains a determinant of human disease. Hosts: Vincent Racaniello, Alan Dove, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Jason McLellan wins MacArthur Award (NPR) 2025 Nobel Prizes Physiology or Medicine (Nobel Prizes) Huntington Disease treatment (BBC) Structure of archaeal tailed virus (Sci Adv) Discovery of Legionella phage (Sci Adv) Microbe of the Month: Legionella (Trends Micro) Letters read on TWiV 1261 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Alan – Specimen of the last female Great Auk finally identified. Jolene – Ribosome studio on IG Vincent – Greater noctule bats prey on and consume passerines in flight Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about Jane Goodall's death and the Nobel prize in Physiology/Medicine for understanding immune system control before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, if 2 doses of the influenza vaccine are better for protection of first season children, if COVID-19 negatively impacts pregnancy and the unborn child, efficacy of long-acting monoclonal antibody against symptomatic COVID-19, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, long COVID in pediatrics, association of COVID-19 with new-onset vascular dementia and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Jane Goodall's legacy: three ways she changed science (Nature) They understood how the immune system is kept in check (The Nobel Prize) Daniel Griffin: The Nobel Prize for Understanding Autoimmune Disease (WNYC: New York Public Radio) Kennedy's Ties to Ally Leading Vaccine Lawsuits Raise Ethical Concerns (NY Times) Ebola outbreak in southern Congo shows signs of containment with no new cases, WHO reports (AP News) Ebola Disease (WHO: African Region) Premature baby dies from measles in Alberta as cases throughout province near 2,000(Global News) DOH Issues Advisory After Measles Detection in City of Oswego Wastewater (Finger lakes dailynew.com) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Influenza-Associated Pediatric Deaths — United States, 2024–25 Influenza Season (CDC: MMWR) ACIP Recommendations Summary (CDC: Influenza) American Academy of Pediatrics Flu and Children (CDC: Influenza (flu)) Comparison of 2 Doses vs 1 Dose in the First Season Children Are Vaccinated Against Influenza (JAMA: Open Network) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Efficacy and safety of respiratory syncytial virus vaccines(Cochrane Library) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Neonatal outcomes among pregnant women with COVID-19 (BMC Pregnancy and Childbirth) Safety and Efficacy of Pemivibart, a Long-Acting Monoclonal Antibody, for Prevention of Symptomatic COVID-19 (CID) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Retreatment With Nirmatrelvir/Ritonavir Following Return of COVID-19 Symptoms and SARS-CoV-2 Positivity (CID) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long COVID associated with SARS-CoV-2 reinfection among children and adolescents in the omicron era (RECOVER-EHR) (LANCET: Infectious Diseases) Prevalence and duration of clinical symptoms of pediatric long COVID (Frontiers in Pediatrics) COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years(NPJ| dementia) Reaching out to US house representative Letters read on TWiV 1260 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews experiments to understand infection, pathogenesis, and transmission of avian H5N1 influenza virus in goats, and identification of a cellular receptor for tick-borne encephalitis virus. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Public trust in science (Nature) Culling of H5N1 ostriches in Canada (Science) H5N1 in goats (Cell Rep) Receptor for tick-borne encephalitis virus (Nature) Letters read on TWiV 1259 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Astronomers find clues suggesting Planet Y Alan – A tower of worms wriggles like a single organism Vincent – The EPA Is Ending Greenhouse Gas Data Collection. Who Will Step Up to Fill the Gap? Listener Picks Jay – Who Killed the Electric Car Douglas – Measles and Polio Down in the Schoolyard – Marsh Family parody Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the ongoing Ebola outbreak in DRC, increases in screwworm diagnoses, a pertussis death in Mississippi before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, monoclonal antibody therapy against RSV, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, olfactory dysfunction following SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Ebola Disease (WHO: African Region) Mexico sees 32% jump in flesh-eating screwworm cases since August as cases move north (Reuters) Pediatric Pertussis Death Reported (Mississippi State Department of Health) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Measles (CDC: Measles Rubeola) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) Influenza-Associated Pediatric Deaths — United States, 2024–25 Influenza Season (CDC: MMWR) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Nirsevimab Administration and RSV Hospitalization in the 2024-2025 Season (JAMA: Open Network) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Efficacy and safety of respiratory syncytial virus vaccines (Cochrane Library) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Olfactory Dysfunction After SARS-CoV-2 Infection in the RECOVER Adult Cohort (JAMA: Open Network) Reaching out to US house representative Letters read on TWiV 1258 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

From ESCV 2025, Vincent speaks with Elke Wollants about a project to identify SARS-CoV-2 and other viruses in toilet waste from airplanes. Host: Vincent Racaniello Guest: Elke Wollants Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Laboratory for Clinical and Epidemiological Virology (KU Leuven) Virologists in Greece (TWiV 1255 from ESCV) Airplane wastewater surveillance for pathogens (SSRN) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explains experiments to create genetically modified chickens that are resistant to avian influenza infection, and discovery of combination antiviral therapy for HTLV-1 infection. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Creating avian influenza virus resistant chickens (Nat Comm) Antiretroviral therapy and apoptosis inhibition for HTLV-1 (Cell) HTLV-1 infection (Cleveland Clinic) Letters read on TWiV 1257 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Rich – Chagas Disease, an Endemic Disease in the United States Alan – Archive of molecular biology artifacts ends its long, strange trip at a museum Vincent – The World's Oceans Are Hurtling Toward Breaking Point Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Vincent travels to Thessaloniki, Greece to attend the 27th meeting of the European Society for Clinical Virology, where he speaks with Pamela Vallely, ESCV President, and Piotr Kramarz, Chief Scientist, European CDC, about the activities of ESCV and ECDC. Host: Vincent Racaniello Guests: Piotr Kramarz and Pamela Vallely Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello lament the anti-vaccine, anti-science composition of the ACIP, US cases of Chagas disease, the Ebola vaccination campaign in the DRC, the death of an infant in LA due to measles complications (SSPE), before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, use of monoclonal antibodies against influenza, the lack of adverse effects of the COVID-19 mRNA in both non-pregnant and pregnant women, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, immune cell infiltration into the central nervous system during long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Northeast US states form health alliance in response to federal vaccine limits (Reuters) MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP) (CDC: ACIP) Viewpoint: Four tips for understanding this week's ACIP meeting (CIDRAP) From Data to Decisions: The Evidence Base for 2025 Fall/Winter Immunizations (CIDRAP) Viewpoint: Four tips for understanding this week's ACIP meeting (CIDRAP) Vaccine Integrity Project (CIDRAP) Chagas Disease, an Endemic Disease in the United States (CDC: Emerging Infectious Diseases) Ebola vaccination begins in the Democratic Republic of the Congo (WHO: Democratic Republic of Congo) Ebola Disease (WHO: African Region) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) L.A. child dies from complication of measles infection contracted in infancy (LA Times) Tracking County-Level Measles Cases in the US (JAMA) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza (NEJM) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Moderna Announces Updated COVID-19 Vaccine Against LP.8.1 Variant Generates Strong Immune Response in Humans (Access Newswire) Adverse events associated with COVID-19 vaccination or diagnosis among pregnant and non-pregnant women in the United States, 2021-2022 (International Journal of Infectious Diseases) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Infectious Disease Society guidelines for treatment and management (ID Society) PAXLOVID-nirmatrelvir and ritonavir : highlights of prescribing information (Pfizer) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer) PAXCESSTM offers access and affordability options to patients prescribed PAXLOVIDTM (nirmatrelvir tablets; ritonavir tablets) (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID CSF immune cell alterations in women with neuropsychiatric Long COVID  (JID) Reaching out to US house representative Letters read on TWiV 1254 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Vincent travels to Waterville Valley, NH to attend the Harvard virology retreat, where he speaks with Aaron Schmidt, Ben Gewurz, and Tatum Sass about their careers and their research on influenza virus, Epstein-Barr virus, and CAR-T cells. Hosts: Vincent Racaniello Guests: Aaron Schmidt, Ben Gewurz, and Tatum Sass Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Harvard Program in Virology Conserved sites on H1 and H3 HA (Sci Adv) Antigenic drift expands viral escape (Immunity) EBV LMP1 drives B cell oncometabolism (PLoS Path) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discuss the continued Legionnaire's outbreak in Harlem, invasive Asia longhorned tick and associated disease, potential Ebola outbreak in the Congo, Florida ending childhood vaccine mandates, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, SARS-CoV-2 spillover into household/domestic dogs, real data demonstrating the benefits of COVID-19 vaccines, states that increase access to COVID-19 vaccines, effective and availability to PAXLOVID, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, the beginning of numerous long COVID clinical studies and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Legionnaires' Disease: In Harlem (NYC Health) 2 dead, dozens sickened by Legionnaires' disease in Westchester County: Officials (NBC News) Invasive longhorned tick found for 1st time in New England (AP News) First person bitten by east Asian longhorned tick (AP News) Invasive, disease-carrying tick found in Maine, the farthest northeast it has been spotted (AP News) Suspected cases rise in DR Congo Ebola outbreak (CIDRAP) Ebola in the Democratic Republic of the Congo (CDC: Travelers' Health)  Patricia Mazzei (NY Times) Florida Moves to End Vaccine Mandates for Schoolchildren (NY Times) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) Influenza-Associated Hospitalizations During a High Severity Season — Influenza Hospitalization Surveillance Network, United States, 2024–25 Influenza Season (CDC: MMWR) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Risk factors for severe outcomes of respiratory syncytial virus infection in children (LANCET: Regional Health Europe) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Spillover of SARS-CoV-2 to domestic dogs in COVID-19–positive households: A one health surveillance study (Virus Research) Pfizer and BioNTech Announce Topline Data Demonstrating Robust Immune Response With Their LP.8.1-Adapted COVID-19 Vaccine 2025-2026 Formula  (Pfizer) Minnesota, New York issue executive orders promoting access to COVID vaccines (CIDRAP) No. 52: Declaring a Disaster in the State of New York Due to Federal Actions Related to Vaccine Access(NY State: Executive Order #52) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Patient-Reported Outcomes of Nirmatrelvir Treatment for High-Risk, Nonhospitalized Adults With Symptomatic COVID-19 (OFID) Real-world effectiveness of nirmatrelvir-ritonavir against severe outcomes of COVID-19 in Taiwan (OFID) PAXLOVID-nirmatrelvir and ritonavir : highlights of prescribing information (Pfizer) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer) PAXCESSTM offers access and affordability options to patients prescribed PAXLOVIDTM (nirmatrelvir tablets; ritonavir tablets) (PAXCESS) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Clinical trials explore how Low-Dose Naltrexone could help people with Long COVID (The Sick Times) Three clinical trials for Long COVID are testing JAK inhibitors to treat immune dysregulation (The Sick Times) Research updates, July 29: Stellate ganglion blocks, may help reduce the severity of some symptoms of Long COVID and ME  (The Sick Times) New Long COVID and complex disease center at Mount Sinai set to be a leader in research, clinical care (The Sick Times) RECOVER-TLC announces new Long COVID clinical trials, receives mixed reactions from patient community (The Sick Times) Reaching out to US house representative Letters read on TWiV 1252 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV re-issues our 100th episode which featured a discussion of viruses with David Baltimore, an exemplary scientist and Vincent's exemplary mentor, who passed on 6 September 2025. Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Guest: David Baltimore Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV David's early papers on poliovirus and mengovirus RNA synthesis Reverse transcriptase found by Baltimore and Temin (pdfs) Nobel Prize in Physiology or Medicine 1975 The David Baltimore asteroid belt Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews a study showing that the 2009 influenza pandemic virus disrupted biennial respiratory syncytial virus epidemics in northern Stockholm, and development of broad-spectrum synthetic carbohydrate receptors that inhibit viral entry of coronaviruses, filoviruses, and paramyxoviruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Florida will end all state vaccine mandates (Reuters) New West Coast Health Alliance (Gov Newsome) COVID vaccines to be more accessible in NY State (CBSNews) Colorado makes COVID vaccines accessible (Denver Post) Massachusetts makes COVID vaccines accessible (Boston dot com) Viral interference disrupts RSV biennial pattern (Nat Comm) Broad-spectrum antiviral carbohydrate receptors (Science Adv) Pedantry about ‘in cellulo‘ (Protocol Online) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Revolutionary Bee “Superfood” Could Save Collapsing Colonies (U Oxford) Kathy – Margaret W. Rossiter, Who Discovered Women of Science, Dies at 81 Rich – Scientists track humpback whale migration with help from AI (Happywhale) Alan – You're probably using the wrong dictionary (Alan's first work of fiction) Vincent – Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in a Child with No Known Exposure Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello is shocked by COVID vaccine restrictions and uncertainties such as pharmacy stock, the ACIP meeting roster and whether it guidance is legal, 3 new ACIP members all anti-vaccine, ending of childhood vaccine mandates in Florida, the continued Legionnaire's outbreak in Harlem, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, cardia benefits of the influenza vaccine, presence of SARS-CoV-2 antibodies in breast milk following vaccination, the use of antiviral nasal sprays to treat COVID 19, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Can You Still Get the Covid Shot? (NY Times) Meeting of the Advisory Committee on Immunization Practices (Federal Register) Cassidy Calls for Vaccine Committee Meeting to be Postponed Following CDC Departures(US Senate Committee on Health, Education, Labor and Pensions) Catherine Stein (Brownstone Institute) CIP to review COVID, hep B, and MMRV vaccine recommendations at September meeting (CIDRAP) Kennedy plans to add new members to an influential vaccine advisory panel. (NY Times) Patricia Mazzei (NY Times) The Steep Cost of Ron DeSantis's Vaccine Turnabout (NY Times) Florida Moves to End Vaccine Mandates for Schoolchildren(NY Times) Legionnaires' Disease: In Harlem(NYC Health) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2025–26 Influenza Season (CDC: MMWR) ACIP Recommendations Summary (CDC: Influenza (Flu)) Flu vaccines show benefits for the heart in new studies (CIDRAP) Risk of Myocarditis or Pericarditis With High-Dose vs Standard-Dose Influenza Vaccine (JAMA: OPEN) High-Dose vs Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults (JAMA: Cardiology) Influenza vaccination to improve outcomes for patients with acute heart failure (PANDA II) (LANCET) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Syncytial Virus Immunization Coverage Among Infants Through Receipt of Nirsevimab Monoclonal Antibody or Maternal Vaccination (CDC: MMWR) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV) SARS-CoV-2 Vaccine-Elicited Antibody Responses in Human Milk (Journal of Pediatric Infectious Diseases Society) Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial (CID) Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections (JAMA Internal Medicine) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese (CID) Paxlovid (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia: Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Florida moves to kill vaccine mandates; state surgeon general slams them as ‘slavery' (Herald-Tribune) Letters read on TWiV 1250 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews the major shakeup in CDC leadership, herpes simplex virus infection doubles the risk of dementia, and the prototypic crAssphage is a linear phage-plasmid. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV CDC director ousted? (CNN) Herpes simplex infection doubles risk of dementia (J Alzheimers Res) Fishing for viruses in senile (TWiV 519) Epstein-Barr virus and MS (TWiV 869) Taking a shot at dementia (TWiV 1207) crAssphage is linear phage-plasmid (Cell Host Microbe) Crassvirales (MDPI) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Research posts on Bluesky are more original — and get better engagement Rich – Rabbits With Hornlike Growths Are Hopping Around Colorado. Are They OK? (Wiki on Shope papilloma virus) Jolene – Lessons Learned: Stories from Women Leaders in STEM Vincent – What Makes This Song Great? “Smells Like Teen Spirit” Nirvana Listener Picks Lori – Tolga bat hospital Emmett – An author recommendation: Peter Watts Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are dismayed about the recent attack on public health the firing of the director of the CDC as well as resignation of 3 others members of the agency's leadership, the continued Legionnaire's outbreak in Harlem, suspension of Ixchiq the Chikungunya virus attenuated infectious vaccine, the first US case of New World screwworm before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, association Guillian-Barré syndrome with RSV vaccination, guidelines for using RSV vaccines, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the American College Obstetricians and Gynecologists recommendations for the COVID, RSV and influenza vaccines, FDA approval letters for Pfizer, moderna and Novagax COVID vaccines including label changes for use in those between 5 through 64 years, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode White House Says New C.D.C. Director Is Fired, but She Refuses to Leave (NY Times) CDC director refuses to leave after White House order (BBC) Legionnaires' Disease: In Harlem(NYC Health) New York City Health Department Provides Update on Community Cluster of Legionnaires' Disease in Central Harlem(NYC Health: Promoting and protecting the City's health) FDA Update on the Safety of Ixchiq (Chikungunya Vaccine, Live) (FDA) Vimkunya (Bavarian Nordiac) U.S. and Panama for the control of the Screwworm pest (COPEG) Rare human case of flesh-eating parasite New World screwworm identified in US(CNN) USDA Announces Sweeping Plans to Protect the United States from New World Screwworm (USDA) HHS details New World screwworm response after human case(CIDRAP) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Measles vaccine recommendations from NYP (jpg) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Relative effectiveness of high-dose versus standard-dose influenza vaccine against hospitalizations and mortality according to frailty score (JID) FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) ENFLONSIA: novel drug approvals 2025 (FDA) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Evaluation of Guillain-Barré Syndrome (GBS) following Respiratory Syncytial Virus (RSV) Vaccination Among Adults 65 Years and Older (FDA) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Veering from CDC, ACOG recommends maternal vaccination against COVID-19 (CIDRAP) ACOG Releases Updated Maternal Immunization Guidance for COVID-19, Influenza, and RSV (American College of Obstericians and Gynecologists) COVID-19 Vaccination Considerations for Obstetric–Gynecologic Care (American College of Obstericians and Gynecologists) Pfizer and BioNTech's COMIRNATY® Receives U.S. FDA Approval for Adults 65 and Older and Individuals Ages 5 through 64 at Increased Risk for Severe COVID-19 (Pfizer)  COMIRNATY approval letter (FDA) Moderna Receives U.S. FDA Approval for Updated COVID-19 Vaccines Targeting LP.8.1 Variant of SARS-CoV-2 (FEEDS) SPIKEVAX approval letter (FDA) Novavax's Nuvaxovid 2025-2026 Formula COVID-19 Vaccine Approved in the U.S (Novavax) NUVAXOVID approval letter (FDA) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Paxlovid (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1248 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Stanley Plotkin joins TWiV to recount his career as a vaccinologist, having participated in the development of vaccines for polio, rabies, and rubella, and his thoughts on the current anti-science, anti-public health, and anti-vaccine climate. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guest: Stanley A. Plotkin Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Stanley Plotkin (History of Vaccines) Talking about vaccines with Dr. Plotkin (CHOP) Path to eradication of rubella (Vaccine) Status of cytomegalovirus vaccine (J Inf Dis) Human diploid cell vaccines (Dev Biol Stand) IPV an essential part of polio eradication (Clin Inf Dis) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses outbreaks of Vibrio vulnificus and Legionnaire's disease in Harlem, the role of the American Association of Pediatrics defining immunization practices, before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, effective of the high and low does influenza vaccines, association Gullian-Barre syndrome with RSV vaccination, guidelines for using RSV vaccines, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, vascular aging after COVID-19 and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Department of Public Health alerts public to rare Vibrio vulnificus bacteria in coastal waters (Mass.gov) Legionnaires' Disease: In Harlem (NYC Health) Ivermectin to Control Malaria (NEJM) AAP has been leading voice on childhood vaccine recommendations since 1930s (American Academy of Pediatrics) The American Academy of Pediatrics Releases Its Own Evidence-Based Immunization Schedule (American Academy of Pediatrics) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Weekly measles and rubella monitoring (Government of Canada) Health Ministry says unvaccinated 18-month-old dies of measles (Times of Israel) Ten countries in the Americas report measles outbreaks in 2025 (PAHO: Pan American Health Organization) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles vaccine recommendations from NYP (jpg) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Relative effectiveness of high-dose versus standard-dose influenza vaccine against hospitalizations and mortality according to frailty score (JID) FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) ENFLONSIA: novel drug approvals 2025 (FDA) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Evaluation of Guillain-Barré Syndrome (GBS) following Respiratory Syncytial Virus (RSV) Vaccination Among Adults 65 Years and Older (FDA) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Paxlovid (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Accelerated vascular ageing after COVID-19 infection: the CARTESIAN study (European Heart Journal) Reaching out to US house representative Letters read on TWiV 1246 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews fradulent science becoming an industry, FDA may not authorize Pfizer COVID vaccine for young kids, Kennedy won't push strict pesticide regulations conserved betacoronavirus sequences recognized by human T cells, and Bispecific antibodies protect against herpes recurrent disease. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Frontiers in Comparative Systems Virology Fradulent science becomes an industry (Science) FDA may not authorize Pfizer COVID vaccine for young kids (CIDRAP) Kennedy Won't Push Strict Pesticide Regulations (NY Times) Conserved betacoronavirus sequences recognized by human T cells (Cell) Bispecific antibodies protect against herpes recurrent disease (Cell Rep) Letters read on TWiV 1245 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – New Study Suggests Using AI Made Doctors Less Skilled at Spotting Cancer Alan – Save the Microbes effort gets off the ground Vincent – Dr. Vinay Prasad's Catch-22: The Only Way He Can Truly Succeed at His Job is to Get Fired Again Listener Picks Chaim – “Virus Hunters” by Greer Williams Bridget – Wave Life Sciences and their potential treatment for Alpha-1 antitrypsin deficiency Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses Vijay Prasad's return to the FDA, revoking of COVID vaccine authorization for young children, the Legionnaires' outbreak in Harlem, the new labeling requirements for Ixchiq, the infectious attenuated Chikungunya vaccine and the importation of H5 influenza virus in Antarctica, before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, guidelines for treating COVID-19, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, the association of “virus rebound” and post-acute sequelae among hospitalized patients, how virus infection particularly influenza and SARS-CoV-2 may ‘re-activate' dormant cancer cells and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Prasad returns to the FDA (Washington Post) Pfizer Covid vaccine for young children may not be renewed by FDA (The Guardian) Report suggests FDA may not reauthorize Pfizer COVID vaccine for young kids (CIDRAP) Factors Associated With Pediatric COVID-19 Mortality: A Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) Study (Journal of Pediatric Infectious Diseases Society) Legionnaires' Disease: In Harlem (NYC Health) Recommended Pause in Use of Ixchiq (Chikungunya Vaccine, Live) in Individuals 60 Years of Age and Older While Postmarketing Safety Reports are Investigated (FDA) FDA Removes Recommended Pause in Use and Approves Required Updated Labeling (FDA) Chikungunya Vaccines (CDC: Chikungunya virus) Chikungunya in China (CDC: Travelers' Health) Travelers' health notices (CDC: Travelers' Health) Areas at Risk for Chikungunya (CDC: Chikungunya virus) Adjuvanted recombinant zoster vaccine is effective against herpes zoster ophthalmicus, and is associated with lower risk of acute myocardial infarction and stroke in adults aged ≥50 years (CID) Tracking HPAIV H5 through a geographic survey of Antarctic seabird populations (Scientific Reports) Report details first suspected H5 avian flu detections in seabirds in Antarctica(CIDRAP) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) ENFLONSIA: novel drug approvals 2025 (FDA) RSV-Network (CDC Respiratory Syncytial virus Infection) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Pemivibart for Pre-exposure Prophylaxis, Vilobelimab for Critical Illness, and Abatacept or Infliximab for Severe or Critical Illness (CID) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Paxlovid (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID TWiV 1243: Capitalism, COVID and Cancer (MicrobeTV) Respiratory viral infections awaken metastatic breast cancer cells in lungs(Nature) Reaching out to US house representative Letters read on TWiV 1244 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV discusses the latest worrisome Executive Order on oversight of federal grantmaking, RFK Jr winds down mRNA viral vaccine development, Lenacapavir, a drug for AIDS prevention and treatment, and how respiratory virus infections awaken dormant metastatic breast cancer cells in lungs. Hosts: Vincent Racaniello, Alan Dove, Rich Condit and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Oversight of Federal grantmaking (Whitehouse.gov) Grantmaking gets a Christofascist (Rasmussen Retorts) HHS winds down mRNA vaccine development (HHS) Lives saved by COVID vaccines (JAMA) Lenacapavir review (Bicochem Pharm) UNAIDS urges Gilead to lower price of lenacapavir (UNAIDS) Gilead and price gouging (Wikipedia) Respiratory virus infections awaken metastatic breast cancer (Nature) Letters read on TWiV 1243 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Xkcd: Geologic Periods Rich – Old Man's War by John Scalzi Alan – The Broken Earth trilogy by N. K. Jemisin Vincent – Cacio e pepe: Good Food pasta recipe sparks fury in Italy Listener Pick Linda – DNA captured in air could identify life forms Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello re-address the dangers of drinking raw milk, the Legionnaire's outbreak in Harlem and results of a vaccine knowledge survey done by emergency departments before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, reports of influenza-associated acute necrotizing encephalopathy or neuropsychiatric events in children, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Pfizer and MODERNA vaccines against the JN.1 variant, risk of children developing severe disease from SARS-CoV-2 infection, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, the association of “virus rebound” and post-acute sequelae among hospitalized patients, effectiveness of COVID-19 vaccines against long COVID, predictors for distinct COVID-19 sequelae including immune disturbances and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Florida Department of Health Provides Update on Raw Milk(Florida Health) Raw milk linked to 21 E coli, Campylobacter infections in Florida (CIDRAP) Legionnaires' Disease: In Harlem (NYC Health) NYC health officials report Harlem Legionnaires' outbreak(CIDRAP) Emergency Department Survey of Vaccination Knowledge, Vaccination Coverage, and Willingness to Receive Vaccines in an Emergency Department Among Underserved Populations  (CDC: MMWR) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Influenza-Associated Acute Necrotizing Encephalopathy in US Children (JAMA) Influenza With and Without Oseltamivir Treatment and Neuropsychiatric Events Among Children and Adolescents(JAMA Neurology) FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) ENFLONSIA: novel drug approvals 2025 (FDA) RSV-Network (CDC Respiratory Syncytial virus Infection) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Effectiveness of the BNT162b2 and mRNA-1273 JN.1-adapted vaccines against COVID-19-associated hospitalisation and death: a Danish, nationwide, register-based, cohort study (LANCET: Infectious Diseases) Hospitalization for COVID-19 and Risk Factors for Severe Disease Among Children: 2022–2024 (Pediatrics) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Metformin and Time to Sustained Recovery in Adults With COVID-19 (JAMA Internal Medicine) Drug interaction checker (University of Liverpool) Paxlovid (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) SARS-CoV-2 rebound and post-acute mortality and hospitalization among patients admitted with COVID-19(Nature Communications) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Effectiveness of COVID-19 vaccines against post COVID-19 condition/long COVID (CMI: Clinical Microbiology and Infection) Precision Symptom Phenotyping Identifies Early Clinical and Proteomic Predictors of Distinct COVID-19 Sequelae (JID) Systemic and SARS-CoV-2 specific Immune Disturbances in Individuals With Post–COVID Syndrome (JID) Reaching out to US house representative Letters read on TWiV 1242 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reports the administration putting a choke hold on billions of NIH health research funding, US Senators tell scientists they want to protect the NIH budget, then review a classic experiment showing the mechanism of DNA replication, and explain how jumbo phage DNA is transcribed in a membrane-bound compartment before transfer into proteinaceous “nucleus” compartment. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, Brianne Barker, Jolene Ramsey, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV 5:13 Chokehold on billions in NIH funding (WSJ) Senators want to protect NIH budget (Nature) Replication of DNA in E. coli (PNAS) Biography of Franklin Stahl (DNA Learning Center) Franklin Stahl, 95 (Caltech Magazine) FW Stahl dies (NY Times) Requiem for a machine (Small Things Considered) Membrane and protein bound organelles during phage infection (Cell Host Micr) Letters read on TWiV 1241 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Benefits of interacting with Nature Brianne – “Why Trust Science” Essay Kathy – Dental floss delivery of vaccines to mice Rich – The Monk in the Garden Jolene – JWST COSMOS-Web Interactive Map viewer Vincent – New Injectable Recommended by Europe for HIV Prevention Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.