Podcasts about sk2

Simple Kid - aka Kieran MacFeely - discusses his two albums from the early 00s – simply titled 1 and 2. Sometimes they're referred to as SK1 and SK2. MacFeely first came to prominence in the late 1990s when The Young Offenders, the Cork glam-infused band he fronted released a couple of memorable singles, but their big break never materialised. Kieran took some time out after The Young Offenders and reemerged in 2002 as Simple Kid, he bought a microphone, a laptop and an 8-track tape machine and released two singles on Fierce Panda Records. Two acclaimed albums followed. He was compared to Badly Drawn Boy and Beck and memorably the NME called him “the post-modern Bob Dylan”. After supporting Kings of Leon on a US tour in 2007 he disappeared. Last year Simple Kid returned with his third album, SK3: Health & Safety. In April 2023 he played his first gig in 15 years.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.09.15.508019v1?rss=1 Authors: Qiu, H., Miraucourt, L., Petitjean, H., Davidova, A., Levesque-Damphousse, P., Estall, J. L., Sharif-Naeini, R. Abstract: The nervous system processes sensory information by relying on the precise coordination of neuronal networks and their specific synaptic firing patterns. In the spinal cord, disturbances to the firing pattern of the tonic firing parvalbumin (PV)-expressing inhibitory interneuron (PV neurons) disrupt the ability of the dorsal horn to integrate touch information and may result in pathological phenotypes. The parvalbumin protein (PVp) is a calcium (Ca2+)-binding protein that buffers the accumulation of Ca2+ following a train of action potential to allow for tonic firing. Here, we find that peripheral nerve injury causes a decrease in PVp expression in PV neurons and makes them transition from tonic to adaptive firing. We also show that reducing the expression of PVp causes otherwise healthy adult mice to develop mechanical allodynia and causes their PV neurons to lose their high frequency firing pattern. We show that this frequency adaptation is mediated by activation of SK channels on PV neurons. Further, we show their tonic firing can be partially restored after nerve injury by selectively inhibiting the SK2 channels of PV neurons. We also reveal that a decrease in the transcriptional coactivator, PGC-1 causes decrease PVp expression and the development of mechanical allodynia. By preventing the decrease in PVp expression before nerve injury, we were able to protect mice from developing mechanical allodynia. Our results indicate an essential role for PVp-mediated calcium buffering in PV neuron firing activity and the development of mechanical allodynia after nerve injury. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer

In this episode of the "Coast To Coasties" Podcast, we continue our conversation with Storekeeper Second Class Hurley in Part 2 of 2 in our two part series. We continue into a detailed discussion of Sean's life as a storekeeper in the U.S Coast Guard and some of the interesting jobs and opportunities he has had with this rating. We further go into discussing his recent trip up to Greenland for Joint Operations with Denmark and France. Many sailors have had an interesting journey during their time in the Coast Guard, but SK2 has truly a one of a kind adventure you do not want to miss hearing! Anyone interested or thinking about going storekeeper is definitely going to want to turn on this episode.

ミスト状のファンデーションが主流になる日がくるかも〜と思ってたけど、ならなかったね。調べたらSK2エアタッチファンデーション（スプレー状の）は販売終了してました。 毎回好きな色味を自動で調合できる、YSL ROUGE SUR MESUREは、税込41,800円だそうです。 ------------------------------------------ Twitter（更新お知らせ他） https://mobile.twitter.com/umeshio_desu note（最近時々書いてる） https://note.com/umeshidesu ------------------------------------------- #うめしお2204 #美容 #メイク

A conversation with trumpet player Mike Vax (lead with the Stan Kenton Orchestra 1970-72) ahead of his performances at the Wigan International Jazz Festival 7th- 10th July 2022.His performances in Wigan will be with Wigan Youth Jazz Orchestra on the afternoon of Saturday 9th July and with SK2 Jazz Orchestra directed by Dave Tyas on the afternoon of Sunday 10th July SK2 are a band based in North West UK and dedicated to the performance of the music of Stan Kenton. (To hear more on SK2 listen to Episode 2 of his podcast)It's FIFTY years since Mike played lead trumpet with the Stan Kenton Orchestra when they toured the UK and recorded a full length TV feature in London and from which an album was produced. The personnel, although not listed on the album, included in the trumpet section Jay Saunders, Mike Vax, Dennis Noday, Ray Brown and Joe Marcinkiewicz.  Mike is director of the Stan Kenton Legacy Orchestra who have been together for 32 years and performed 23 national tours in the USA. Mike is an endorsee for the Warburton Company and plays an instrument designed and built by Terry Warburton..he named it the VAXINATOR. Get your tickets now for the Wigan International Jazz Festival at www.justaddtickets.co.uk and come meet and chat with Mike Vax The following tracks appear in this EpisodeBeer Jersey Boogaloo Dan ShoutA Little Minor Booze Willie MaidenChiapos Hank Levy Stan Kenton Orchestra Speak Low Mike Vax Big Band Intermission Riff Ray Wetzel Malaga Bill Holman Stan Kenton Orchestra Eager Beaver Mike Vax Big Band with Stan Kenton Alumni Episode 10 also contains details of the Wigan International Jazz Festival see www.wiganjazzfest.co.uk www.wiganjazzclub.co.uk www.musiccontinuum.co.uk and www.justaddtickets.co.uk 

這一集接著S4EP16 山姆他...山姆他回來了 [SK2有料黑白講]來繼續談談面對挫折以及身邊不知道那些是不是真的有肩膀的工作夥伴, 家人或隊友時到底心裡是如何準備去面對這一切? 試著從生活中的小事看到自己的影響力進而慢慢建立對自己的信心說不定會是一個很好的練習喔! (廣告時間：像是凱莉如果收到你對節目的正面回應都會開心一整天, 就不要再以為自己沒有影響力了, 五星評論給它留下去吧^^) --- 喜歡我們頻道無痛學習知識的主軸? 點擊這個連結 用一杯焦糖瑪奇朵的錢支持我們繼續做出與眾不同的知識企劃! 想針對本集節目內容做進一步討論或是跟我們聯絡? 快寫信 給我們 yowhatsup.podcast@gmail.com 到Apple podcast下面給我們留評論跟我們互動 在Firstory的單集專屬留言區留言 來Yo! What's Up 在幹嘛的IG 或是臉書 找我們 或是加入我們的臉書秘密VIP好好生活小圈圈 一起在忙亂生活中找到秩序好好過生活 我們等你!!! -- 頭尾配樂版權宣告： 浪漫民謠配樂 編曲： Music Time 版權音樂團隊 作曲： Music Time 版權音樂團隊 製作： Music Time 專業配樂音效後製 發行： 更多優質播客音樂/後製服務>> https://reurl.cc/AgE6Lp 授權： https://creativecommons.org/licenses/by-nd/4.0/deed.zh_TW 連結： 原創音樂人需要你的贊助>> https://reurl.cc/MZY6OL Powered by Firstory Hosting

這一集的SK2有料黑白講讓我們來聽聽山姆與凱莉和娃娃魚上山度假卻被迫發足狂奔的故事！到底山上的湖濱度假區發生了什麼事呢？ --- 喜歡我們頻道無痛學習知識的主軸? 點擊這個連結 用一杯焦糖瑪奇朵的錢支持我們繼續做出與眾不同的知識企劃! 想針對本集節目內容做進一步討論或是跟我們聯絡? 快寫信 給我們 yowhatsup.podcast@gmail.com 到Apple podcast下面給我們留評論跟我們互動 在Firstory的單集專屬留言區留言 來Yo! What's Up 在幹嘛的IG 或是臉書 找我們 或是加入我們的臉書秘密VIP好好生活小圈圈 一起在忙亂生活中找到秩序好好過生活 -- 頭尾配樂版權宣告： 浪漫民謠配樂 編曲： Music Time 版權音樂團隊 作曲： Music Time 版權音樂團隊 製作： Music Time 專業配樂音效後製 發行： 更多優質播客音樂/後製服務>> https://reurl.cc/AgE6Lp 授權： https://creativecommons.org/licenses/by-nd/4.0/deed.zh_TW 連結： 原創音樂人需要你的贊助>> https://reurl.cc/MZY6OL Powered by Firstory Hosting

第三季的最後一集很私心的就留給一直支持[凱莉陪你上下班]這個單元的你, 希望藉由這個仔細回應聽眾第一季到第三季五星評論的特輯(共183集凱莉單口集數真的好瘋狂), 好好的傳遞凱莉在創作的路上能遇到大家, 是感到多麼幸運的噴淚心聲! (是的, 一錄完就跑去抱著我的小狗阿波哭了QQ, 這集真的感情放的有點多啊) VIP糖炒栗子專屬[凱莉陪你上下班]單元播放清單: https://yowhatsup2020.firstory.io/playlists/ckdbztnsd21mv0804f70wym8h ***以下是那些聽眾在他們五星評論提到的亮點集數, 跟還沒有聽過的你分享: 那些敘述蠢狗萌貓的汪言喵語播放清單 https://yowhatsup2020.firstory.io/playlists/ckdxbirr1wg9408807qglz5jd S2Ep26 新冠肺炎來臨時，聽小確幸的聲音[凱莉陪你上下班] https://open.firstory.me/story/cka1jpeyelg5c0873ssnw3rag/platforms S2Ep3 凱莉真的是跑路王&搬家真的好辛苦之她搬完第18次家了[SK2黑白講] https://open.firstory.me/story/ck9uvd9i7ol550873frvi6puh/platforms S2Ep4 凱莉真的是跑路王&她搬了18次家到底是在搬什麼心酸的[SK2黑白講] https://open.firstory.me/story/ck9uvd9iaol57087311hqfi3h/platforms S2EP66 情境設定在一天累壞之後倒在沙發上邊聽音樂邊聽好友在廚房為自己準備食物的ASMR [摯友ASMR] https://open.firstory.me/story/ckbv1eksle00l0918s2jt0an3/platforms S2EP71 情境設定在加班累壞隔天早上邊聽好友在廚房為自己泡茶&整理廚房,邊吃她帶來早餐的ASMR [摯友ASMR] https://open.firstory.me/story/ckcd21q62b0tf09180sokrqwv/platforms S2EP67 會有用嗎? 那個人稱能夠緩解壓力, 幫助睡眠, 達到身心靈平靜的ASMR? 我們又該如何從中受益? [凱莉陪你上下班] https://open.firstory.me/story/ckbvxkzl1m1lh0918eh224ue9/platforms S3EP42 丟光過期食品準備新開始-年末斷捨離行動5-1 [凱莉陪你上下班] https://open.firstory.me/story/ckj7rt9apbre10984afbn8gw9/platforms S3EP44 捨棄不再讓你閃閃發光的衣服-年末斷捨離行動5-2 [凱莉陪你上下班] https://open.firstory.me/story/ckjb4v5korotc083737y0yl3w/platforms S3EP45 終結雜亂浴室看這裡-年末斷捨離行動5-3 [凱莉陪你上下班] https://open.firstory.me/story/ckji3epempad70876hxtvbjyk/platforms S3EP46 三大書籍紙張文件斷捨離心法來了-年末斷捨離行動5-4 [凱莉陪你上下班] https://open.firstory.me/story/ckjkjew1dzo9508208lmx4mp2/platforms S3EP48 終極廚房斷捨離大法-年末斷捨離行動5-5[凱莉陪你上下班] https://open.firstory.me/story/ckjqmqkpypun808761zmk6rvi/platforms S3EP53 斷捨離常犯的三大錯誤-年末斷捨離行動SP [凱莉陪你上下班] https://open.firstory.me/story/ckkd5as9oz2q40854utvvcoci/platforms S2EP97 善加利用那個沒人教你的選擇小技巧, 解決自己對應盡責任的奇摩子問題, 迎向更理想的人生 [凱莉陪你上下班] https://open.firstory.me/story/ckdf2aetvlrt60804rg6209go/platforms S2Ep8 [凱莉陪你上下班] 翻轉蕃茄鐘的惡搞時間管理法 https://open.firstory.me/story/ck9uvd9inol5f0873b6g1khti/platforms S2EP95 覺得每天喝8杯水超難? 別怕, 量身定制內化喝水習慣的長效策略來啦 [凱莉陪你上下班] https://open.firstory.me/story/ckd8c5cusrhsz0856zrsvz7fk/platforms 凱莉主講價值4800的好睡衛教工作坊(4堂) https://open.spotify.com/playlist/7zV9XN61WLUHZM2cJIPYdN?si=D1kQQbd4Qp244s6-eQXc-Q&dl_branch=1 [凱莉陪你上下班] 是Yo! What's Up在幹嘛的短篇通勤單元, 內容多元包含了壓力管理、時間管理、收納專家建議、深入淺出行為學、以及一些日常有趣的新聞, 用滿滿的心意陪伴聽眾的通勤以及空閒時間! 想到的時候, 請讓我的聲音陪你走一段吧。 --- 喜歡我們頻道無痛學習知識的主軸? 點擊這個連結 用一杯焦糖瑪奇朵的錢支持我們繼續做出與眾不同的知識企劃! 想針對本集節目內容做進一步討論或是跟我們聯絡? 快寫信 給我們 yowhatsup.podcast@gmail.com 到Apple podcast下面給我們留評論跟我們互動 在Firstory的單集專屬留言區留言 來Yo! What's Up 在幹嘛的IG 或是臉書 找我們 或是加入我們的臉書秘密VIP好好生活小圈圈 一起在忙亂生活中找到秩序好好過生活 我們等你!!! Powered by Firstory Hosting

最近正是看奧運的好日子！大家都跟我們一樣在瘋奧運嗎？還是跟凱莉一樣在擔心遛狗時地板太燙呢？最新一期SK2有料黑白講跟大家分享山姆凱莉的盛夏！我們準備要換季囉！跟我們一起期待新一季的內容吧！ -- 喜歡我們頻道無痛學習知識的主軸? 點擊這個連結 用一杯焦糖瑪奇朵的錢支持我們繼續做出與眾不同的知識企劃! 想針對本集節目內容做進一步討論或是跟我們聯絡? 快寫信 給我們 yowhatsup.podcast@gmail.com 到Apple podcast下面給我們留評論跟我們互動 在Firstory的單集專屬留言區 留言 到MixerBox的單集專屬留言區留言 來Yo! What's Up 在幹嘛的IG 或是臉書 找我們 或是加入我們的臉書秘密VIP好好生活小圈圈 一起在忙亂生活中找到秩序好好過生活 感謝以下贊助的聽眾: Powered by Firstory Hosting

Episode 2 of Jazz Notes, Jazz Conversations & More features conversations with Dave Tyas of the SK2.

Der Spezialist für Sehbehinderten-Lesegeräte Steller Technology stellt seine Produktpallette made in Germany und die Firmenphilosophie vor, die auf größtmögliche Flexibilität und Kombinierbarkeit diverser Kameras, Anschlüsse und Stative setzt. Etwas ausführlicher vorgestellt wird dabei das Lesegerät SK2, das mit einem Curved-Monitor, wenig Platzbedarf und edlem Design aufwartet. Näher besprochen wird auch Vision Mix - eine mobile Kamera für Schülerinnen und Schüler und mit einem Gewicht von unter einem Kilo das wohl leichteste System dieser Art auf dem Markt. Aus diesem Abschnitt stammt auch das wörtliche Zitat aus dem Titel dieser Podcast-Episode - nutzt es so wie ihr es wollt - die Kamera kann es einfach!

「不需要反派, 好好活著這件事本身就是個大反派」多災多難的2020終於結束了！在2020的末尾連假，Kelly想要給家裡買新窗簾保護隱私但是卻弄出糗事？Sam在年末的連假中破天荒連看兩部韓劇？！來聽聽SK2在2021的黑白講回顧剛結束了的假期吧！ --- 歡迎寫信給我們yowhatsup.podcast@gmail.com #中文podcast #中文播客 #台灣podcast #podcast #taiwanpodcast #yowhatsup在幹嘛 #日更 #衛教 #公衛 #2021 #新年快樂 --- 歡迎你到Apple podcast下面給我們留評論, 或是直接到Firstory的單集專屬留言區底下跟我們討論在這一集裡你有興趣聊聊的內容 https://open.firstory.me/story/ckjp6xvf5xpcg08932ub6wkk7?m=comment --- 我們除了在臉書 https://www.facebook.com/yowhatsup2020 跟IG https://www.instagram.com/yowhatsup_2020/ 出沒之外, 還建了一個跟聽眾一起彼此鼓勵好好過生活的VIP群組 https://www.facebook.com/groups/323214312251981 歡迎想要在忙亂生活中找到秩序好好過生活的你來一起參加, 還有想跟我們聯絡的話, 寫信來吧 yowhatsup.podcast@gmail.com --- 我們頻道的聽眾抖內功能上線了! 點擊這個連結 https://pay.firstory.me/user/yowhatsup2020 用一杯焦糖瑪奇朵的錢支持我們(是的凱莉喜歡喝XD), 鼓勵我們天天都想做好節目的心! Powered by Firstory Hosting

2021新年首集SK2有料黑白講！山姆與你分享接種 Moderna藥廠COVID疫苗的一手經驗！究竟疫苗打起來是什麼感覺呢？美國疫苗接種進度落後！到底發生什麼事情？歡迎來跟我們一起用新年新希望迎接新的一年！ --- 歡迎寫信給我們yowhatsup.podcast@gmail.com #中文podcast #中文播客 #台灣podcast #podcast #taiwanpodcast #yowhatsup在幹嘛 #日更 #衛教 #公衛 #疫苗 #covid #covid疫苗 #輝瑞 --- 歡迎你到Apple podcast下面給我們留評論, 或是直接到Firstory的單集專屬留言區底下跟我們討論在這一集裡你有興趣聊聊的內容 https://open.firstory.me/story/ckipqh8w7i1y408071zssu4tu?m=comment --- 我們除了在臉書 https://www.facebook.com/yowhatsup2020 跟IG https://www.instagram.com/yowhatsup_2020/ 出沒之外, 還建了一個跟聽眾一起彼此鼓勵好好過生活的VIP群組 https://www.facebook.com/groups/323214312251981 歡迎想要在忙亂生活中找到秩序好好過生活的你來一起參加, 還有想跟我們聯絡的話, 寫信來吧 yowhatsup.podcast@gmail.com --- 我們頻道的聽眾抖內功能上線了! 點擊這個連結 https://pay.firstory.me/user/yowhatsup2020 用一杯焦糖瑪奇朵的錢支持我們(是的凱莉喜歡喝XD), 鼓勵我們天天都想做好節目的心! Powered by Firstory Hosting

在本期「干燥女子」特别节目中，Miya和多姐将从自身情况出发，分享自己多年来使用的美肌好物。也顺便互相安利了一份特别实惠实用的“双十一种草清单”，欢迎收听（那么在日出时刻，是哪一件护肤品可以帮助你开启美好一天呢？期待大家的种草分享。多姐常用分享 ：黛珂牛油紫苏水乳、POLA防晒、SK2小灯泡。miya常用分享：LA MER精华、科颜氏高保湿、雅诗兰黛熬夜小棕瓶。主播 / miya&terry后期剪辑 / 酸黄瓜平台上传 / 旺达视觉设计 / 冯旭文字编辑 / Toto

在本期「干燥女子」特别节目中，Miya和多姐将从自身情况出发，分享自己多年来使用的美肌好物。也顺便互相安利了一份特别实惠实用的“双十一种草清单”，欢迎收听（那么在日出时刻，是哪一件护肤品可以帮助你开启美好一天呢？期待大家的种草分享。多姐常用分享 ：黛珂牛油紫苏水乳、POLA防晒、SK2小灯泡。miya常用分享：LA MER精华、科颜氏高保湿、雅诗兰黛熬夜小棕瓶。主播 / miya&terry后期剪辑 / 酸黄瓜平台上传 / 旺达视觉设计 / 冯旭文字编辑 / Toto

在本期「干燥女子」特别节目中，Miya和多姐将从自身情况出发，分享自己多年来使用的美肌好物。也顺便互相安利了一份特别实惠实用的“双十一种草清单”，欢迎收听（那么在日出时刻，是哪一件护肤品可以帮助你开启美好一天呢？期待大家的种草分享。多姐常用分享 ：黛珂牛油紫苏水乳、POLA防晒、SK2小灯泡。miya常用分享：LA MER精华、科颜氏高保湿、雅诗兰黛熬夜小棕瓶。主播 / miya&terry后期剪辑 / 酸黄瓜平台上传 / 旺达视觉设计 / 冯旭文字编辑 / Toto

終於迎來第三季的第一集SK2有料黑白講, 我們的聽眾敲碗都快要敲破了啊啊啊啊啊~ 這一集要跟大家聊聊我們第三季開播之前山姆跟三隻貓差一點家裡被大水滅頂但是他是如何用智慧在千鈞一髮之際成功逃過一劫的恐怖經驗; 還有凱莉對於reopen之後整個社區洋溢著(把孩子送回學校)快樂氛圍的觀察分享。 --- 歡迎你到Apple podcast下面給我們留評論, 或是直接到Firstory的單集專屬留言區底下跟我們討論在這一集裡你有興趣聊聊的內容 https://open.firstory.me/story/ckfyjrt8x4pl708005zf54n0m?m=comment --- 我們除了在臉書 https://www.facebook.com/yowhatsup2020 跟IG https://www.instagram.com/yowhatsup_2020/ 出沒之外, 還建了一個跟聽眾一起彼此鼓勵好好過生活的VIP群組 https://www.facebook.com/groups/323214312251981 歡迎想要在忙亂生活中找到秩序好好過生活的你來一起參加, 還有想跟我們聯絡的話, 寫信來吧 yowhatsup.podcast@gmail.com --- 我們頻道的聽眾抖內功能上線了! 點擊這個連結 https://pay.firstory.me/user/yowhatsup2020 用一杯焦糖瑪奇朵的錢支持我們(是的凱莉喜歡喝XD), 鼓勵我們天天都想做好節目的心! Powered by Firstory Hosting

聽眾敲碗很久的SK2黑白講來了, 這一集跟大家大概分享一下美國疫情狀況還有解釋一下川普最近到底在跟公衛一把手芬奇鬧什麼小孩脾氣, 聊聊我們兩個人最近的衰事, 還有為攻略雙子座的戀愛講堂揭開序幕。歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們 IG(@yowhatsup_2020)哦～:) 想跟我們聯絡的話, 寫信來吧 yowhatsup.podcast@gmail.com p.s我們頻道的聽眾抖內功能上線了! 點擊下面連結, 用一杯咖啡鼓勵我們做出更多好節目吧^^ --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

The WTC Winnipeg podcast welcomes Chuck Davidson, president and CEO of the Manitoba Chambers of Commerce, to join Mariette Mulaire in chatting with Manitoba businesses. In this episode, Kevin Klaassen, co-owner of SK2 Custom Homes, explains that his company is in fact busier than ever. He touches on the diversity of their target markets, the normality of working with clients remotely and how they've taken advantage of this time to double up on their digital marketing efforts to reach new potential clients.SK2 provides building solutions by means of custom homes. They are built on-site in Altona, Manitoba and transported in one-piece to their final location. 

異軍突起創造不錯流量的系列—SK2黑白講又來了，最近山姆和凱莉又有著什麼可以拿出來分享的生活小故事呢？不知道標題講的是什麼意思？還不快點點進來SK2黑白講系列第三集聽聽看~~~ 歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們的IG(@yowhatsup_2020)哦～:) --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

異軍突起創造不錯流量的系列—SK2黑白講又來了，最近山姆和凱莉又有著什麼可以拿出來分享的生活小故事呢？不知道標題講的是什麼意思？還不快點點進來SK2黑白講系列第三集聽聽看~~~ 歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們的IG(@yowhatsup_2020)哦～:) --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

異軍突起創造不錯流量的系列—SK2黑白講又來了，最近山姆和凱莉又有著什麼可以拿出來分享的生活小故事呢？不知道標題講的是什麼意思？還不快點點進來SK2黑白講系列第三集聽聽看~~~ 歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們的IG(@yowhatsup_2020)哦～:) --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

異軍突起創造不錯流量的系列—SK2黑白講又來了，最近山姆和凱莉又有著什麼可以拿出來分享的生活小故事呢？不知道標題講的是什麼意思？還不快點點進來SK2黑白講系列第三集聽聽看~~~ 歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們的IG(@yowhatsup_2020)哦～:) --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

SK2 黑白講系列第二集—隨著年齡增長而接踵而至的討論其實有的時候比我們想的還能多很多，明明是個搞笑的開場，怎麼聊到最後會有淡淡的憂傷呢？好好珍惜你還可以being sophomoric的年紀吧! 歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們的IG(@yowhatsup_2020)哦～:) --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

SK2 黑白講系列初放送 —- 完全紓壓的無偶包聊天特輯，立志要成為折腰上班族的上下課通勤好夥伴。歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們的IG(@yowhatsup_2020)哦～:) --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

SK2 黑白講系列初放送 —- 完全紓壓的無偶包聊天特輯，立志要成為折腰上班族的上下課通勤好夥伴。歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們的IG(@yowhatsup_2020)哦～:) --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

SK2 黑白講系列初放送 —- 完全紓壓的無偶包聊天特輯，立志要成為折腰上班族的上下課通勤好夥伴。歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們的IG(@yowhatsup_2020)哦～:) --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

SK2 黑白講系列初放送 —- 完全紓壓的無偶包聊天特輯，立志要成為折腰上班族的上下課通勤好夥伴。歡迎你到Apple podcast底下留言跟我分享你聽完這集的想法，還有別忘了追蹤我們的IG(@yowhatsup_2020)哦～:) --- Support this podcast: https://anchor.fm/toby795/support Powered by Firstory Hosting

Rx012 Guest DJ/Producer: The Peverell Brothers Origin: Middlesbrough, UK Genre Styles: House Labels: Jango, SK2, Bahia, Soleado Recordings http://www.reflectresidents.com/ https://www.facebook.com/PeverellBros https://twitter.com/PeverellBros https://www.youtube.com/user/reflectresidents The Peverell Brothers – A DJ/Producing duo hailing from Middlesbrough in the North East of the UK who have been involved in the House Music industry collectively since the late 90’s. The guys who were influenced by big hitters like MAW, Dimitri from Paris, Erick Morillo & Carl Cox have been key figures in the House scene in and around the North East for many years with residencies at some of the area’s most renowned clubs and club nights. They have also held individual summer residencies and regular visits to the world’s party capital – Ibiza and are a well known name on the white isle today. The Peverell Brothers are now a force to be reckoned with in the production world featuring on labels such as State Records, Bahia Music & Wormland Music and are now exclusive artists for French label Jango Music. Their music comes with big support from artists including Stonebridge, Ron Carroll, Tom Novy, K-Klass, Jay C, Jon Fitz, eSQUIRE, Allister Whitehead, Hardsoul, David Vendetta, Vigo Qinan, Lucas Reyes and many more making these guys a huge force in today’s House Music industry. With their experience, musical knowledge & versatility, The Peverell Brothers continuously showcase a Groovy style of House music and always deliver an unforgettable experience.

Lil' 45-minute Drum n' Bass mix to warm things up for this years forthcoming Bodstock Festival Tracklisting: 1. Emperor - Begin (Feat. Georgia Yates) [Critical Music] 2. Zero Method - Groundbreaker [Red Light Records] 3. Dialogue - Won't Budge [Innerground] 4. Frankee - Harlequin [Program] 5. Technimatic - Solace [Shogun Audio] 6. Phase - Ways Of Thought (Feat. Lameduza) [Demand Records] 7. Dose - Simultaneous [SGN:LTD] 8. Braincrack - Bad Business (Loudnoised remix) [Brainshakaz] 9. BTK - Be Yourself [Renegade Hardware] 10. Seven feat. Alys Be - Came To Play (Need For Mirrors remix) [Philly Blunt Records] 11. Serum & Heist - Live At The Apollo [Chronic Records] 12. Mob Tactics - Outrun [Tactical Recordings] 13. Optiv & BTK - Bad Attitude [Blackout Music NL] 14. Dioptrics - Switch (Original mix) [Abducted Records] 15. State Of Mind & Black Sun Empire & Bulletproof - Roulette (Gridlok remix) [SOM Music] For more info on Bodstock go to: www.facebook.com/events/1389604051252468/

In case you missed the guest mix on the OutlawBreakz show on Nubreaks radio.. Tracklist: 1. THE BRAINKILLER - PHANTASMAGORIC (Original mix) [Funn Dark Recordings] 2. KUPLAY - FUCK U (Kid Panel remix) [Sound Break Records] 3. BEATSMACK - ULTIMATUM (Perpetual Present remix) [Diablo Loco Records] 4. TONY LIZANA - MODEL (Quadrat Beat remix) [Desnivel Records] 5. GUAU - ANTIAEREO 13 (Original mix) [Elektroshok Records] 6. SYNTHETIC HYPE - SLAP DA BASS [Diablo Loco Records] 7. HARDNOISE - BREAKAWAY (Blazer remix) [Ruff N Fresh] 8. F-WORD - BABY ON BOARD (Yreane remix) [V.I.M. Breaks] 9. M.E.L.T. - DIRTY SEX (Detach remix) [Breakz R Boss] 10. UTKU S. - TURBO (Original mix) [Tapestop Music] 11. B-PHREAK - YOU ARE SICK [Dusted Breaks] 12. UNDER THIS - DANCING RIGHT [iBreaks] 13. MYAGI - DRUM TOWN (Original mix) [Westway] 14. DIGIBOX - DARK NIGHT (Charlie Kane remix) [Diablo Loco Records]

INFERNO SESSIONS SHOW TRACKLISTING - 11/06/12 1. THE BREAKFASTAZ - KICK IT [MOB] 2. DOGTOWN CLASH - WEST LONDON'S BURNING (Beat Assassins mix) [Westway] 3. WAX EQUESTRIAN - ZIGZAG (Doapmine remix) [Wut Eva] 4. CUT & RUN - BROOKYLN BANGER [Cut & Run] 5. QUADRAT BEAT - BLACKJACK (Original mix) [Expand Records] 6. KWERK - DON'T STOP [Kick It Recordings] 7. NUBOY - AWHAT? (Eshericks remix) [En:Vision Recordings] 8. HARDNOISE - SUNSHINE (Original mix) [Distorsion Records] 9. FATBOY SLIM - STAR 69 (Rogue Element remix) [Skint Records] 10. HARDNOISE - AWAY (B-Phreak remix) [Hard & Hits] 11. ROB RENG - SOLARIZE [Ruff Dog Recordings] 12. PLUMP DJ'S - LIGHT FANTASTIC [Grand Hotel Records] 13. DJ FEN - READY (Original mix) [Spektra Recordings] 14. NAPT - N-FUNK [Sub Frequency Funk] 15. CRISP BISCUIT - AMEN [Crisp Biscuit] 16. SQUATTER - THEY'RE IN MY BOWELS (Strider remix) [Control Breaks] 17. DR. FISH - INFLUENZA (Access Denied remix) [V.I.M. Breaks] 18. KID DIGITAL - DONE WITH THAT (Colombo remix) [Hardcore Beats] 19. FREESTYLERS feat. MILLION DAN - BOOMBLAST (Deekline & Wizard feat. Yolande remix) [Against The Grain] 20. REFRACTURE - JAHOVAH (The Revamp) [Dusted Breaks] 21. DYLAN RHYMES - I AM SWEET (Ctrl Z remix) [Lot 49] 22. THE BRAINKILLER - LA PUTA (Original mix) [Funn Dark Records] 23. BSD - HOPINESS (Original mix) [Mental Machine Muzik] 24. HARDY HARD & LADY WAKS feat. MR X - MINIMAL (Rogue Element remix) [Menu Music] 25. ROCK MASSIVE - YOU KNOW WHY (PH Electro mix) [Armada Music] 26. WAYS AND MEANS - SATIVA SISTER (Original mix) [Audio 23] 27. ELECTRIC SOULSIDE - SOUL ON FIRE [Diablo Loco Records] 28. ENCODE - MAGIC POINTS [Breed 12 Inches]

Review on the SK2 and some on the SK3.

Ion channels are integral membrane proteins present in all cells. They are highly selective and assure a high rate for ions down their electrochemical gradient. In particular, small-conductance calcium-activated potassium channels (SK) are conducting potassium ions and are activated by binding of calcium ions to calmodulin, which is constitutively bound to the carboxy-terminus of each SK channel -subunit. Until now, only three SK channel subunits have been cloned, SK1, SK2 and SK3. Sequence alignment shows that the transmembrane and pore regions are highly conserved, while a high grade of divergence is observed in the amino- and carboxy-termini of the three subunits. In order to determine the expression of the different SK channel subtypes, pharmacological tols such as apamin and d-tubocurarine have been widely used. In this work, I show the characterization of a novel toxin, tamapin, isolated from the scorpion Mesobuths tamulus, which targets SK channels. Our experiments show that this toxin is more potent in blocking SK2 channels than apamin. Furthermore, tamapin only blocked the SK1 and SK3 channels at higher concentrations, with higher efficiency to block SK3 than SK1. Therefore, tamapin should be a good pharmacological tool to determine the molecular composition of native SK channels underlying calcium-activated potassium currents in various tissues. Secondly, I determined the molecular mechanism that prevents the formation of functional SK1 channels cloned from the rat brain (rSK1). Until now, little information was available on the rSK1 channels. rSK1 shows highly sequence identity (84%) with the human homologue, hSK1. hSK1 subunits form functional potassium channels that are blocked by apamin and d-tubocurarine. However, when I expressed rSK1 in HEK-293 cells no potassium currents above background were observed, although immunofluorescence experiments using a specific antibody against the rSK1 protein showed expression of the channel. I generated rSK1 core chimeras in which I exchanged the amino-and/carboxy-terminus with the same region of rSK2 or hSK1. Exchange of amino-and carboxy-terminus or only of the carboxy-terminus resulted in the formation of functional potassium channels. Furthermore, I used these functional chimeras to determine the toxin sensitivity of rSK1 for apamin and d-tubocurarine. Surprisingly, when these blockers wre applied, no sensitivity was observed, although hSK1 and rSK1 show a complete sequence identity in the pore region, which is suggested to contain the binding site for apamin. Finally, I characterized a novel splice variant of the calcium-activated potassium channel subunit rSK2, referred to as rSK2-860. The rSK2-860 cDNA codes for a protein which is 275 amino acids longer at the amino-terminus when compared with originally cloned rSK2 subunit. Transfection of rSK2-860 in different cell lines resulted in a surprising expression pattern of the protein. Th protein formed small clusters around the cell nucleus, but no membrane stain could be observed. This data shows that the additional 275 amino acid-long stretch at the amino-terminus is responsible for retention and clustering of rSK2-860 protein. In order to narrow down the region responsible for this phenotype, I generated truncated proteins. This resulted in the isolation of an 100 amino acid-long region that seems to be responsible for the retention and clustering of rSK2-860 channels. Further truncations and deletions could help us to find the exact signal which is responsible for this characteristic behavior of the rSK2-860 protein.