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Raising awareness about disparities in cancers impacting women, screening among Indigenous populations, and barriers to accessing care is essential. The Association of Cancer Care Centers (ACCC) is dedicating to providing up-to-date information on approaches to improving women's health screening, education, and prevention in Indigenous subpopulations. In this episode, CANCER BUZZ speaks with Tricia Numan, MD, assistant professor of pathology at Roswell Park Comprehensive Cancer Center about geographical challenges to accessing care and strategies for culturally tailored approaches for indigenous women. “[There] are some major things that have happened in not so recent past to native populations, and I think it's really important for health care providers to take that recent history into account when they're caring for native patients.” – Tricia Numan, MD “If you want to culturally tailor your health care I think that it's very important, because it's not a one size fits all.” Tricia Numan, MD Gynecologic Pathologist Assistant Professor of Pathology Department of Pathology & Laboratory Medicine Department of Indigenous Cancer Health Roswell Park Comprehensive Cancer Center Buffalo, New York Resources: Roswell Park Department of Indigenous Cancer Health Oncology Issues Roswell Park Article
CORDIScovery – unearthing the hottest topics in EU science, research and innovation
Why is it so hard to find a vaccine that works well against placental malaria? Ever thought about the challenges of irradiating 300 mosquitoes a second! And how do the dynamics of replication play out in our bodies? Malaria is described by the World Health Organization as ‘perpetuating a vicious cycle of inequity'. Listen on to see how EU scientists are working to understand and mitigate the disease. Catherine Merrick is professor of Parasitology in the Pathology Department at Cambridge University. She studies the human malaria parasite, aiming to improve our understanding of the fundamental biology of the parasite, and the impact of this biology on virulence. Lars Hviid is professor in the Department of Immunology and Microbiology, at the University of Copenhagen. His work has improved our understanding of how people gradually acquire protection from malaria, and furthered the development of vaccines against this deadly parasite. Hanan Lepek is the founder and CEO of Senecio Robotics. He works at the interface of biology and mechanical and software engineering, to create and deploy sterile mosquitoes on a large scale to reduce local mosquito populations.
Dr Sarbar Napakhi arrived in Australia in 1992. With his medical background, when he arrived in Australia, he did three years of residency in medical surgical and emergency. Dr Napakhi also worked as a general practitioner until 1997 when he started his training in Anatomical Pathology. He received his Fellowship of the Royal College of Pathologists Australasia at the end of 2002 and started working at Southern IML (intravascular malignant lymphomatosis) Pathology as a consultant pathologist in 2003. Dr Napakhy is currently Head of Department in Anatomical Pathology at Wollongong University. His areas of interests include urology, lymphoma, head and neck and gastrointestinal Pathology. He re-joined the Pathology Department at Southern IML Pathology in 2016. - Dr. Serbar Nepaxî di sala 1990 de li zanîngeha Selahedîn li Hewlêrê xwendina xwe ya blind kuta kir. Wî di sala 1992 e, koçî Australya kir û sê salan di warên bijîşkî, neştergerî û pizîşkiya awarte de perwerde dît. Dr Nepaxî herweha heta sala 1997 doktorê giştî bû dema wî dest bi perwerdeya patolojiya anatomîk kir wate Lêkolîna li ser nixweşiyên di laş de. Ew di dawiya sala 2002 de Fellowship to the Royal College of Pathologists Australasia bi dest xist. Dr Nepaxî niha serokê Anatomical Pathology li Nexweşxaneya Wollongong, ku ji hêla Southern.IML Pathology ve tê xizmetkirin. Taybetîmendiya Dr Nepaxî di van beşan de ye, urology/mîzdanikê, lîmfoma, nexweşiyên serî û stû, zik û rovî/gastrointestinal.
Can pathology be truly digital without getting rid of glass?In this episode with Dr. Richard Levenson, Professor and Vice Chair for Strategic Technologies at the Pathology Department of UC Davis, you'll learn how close we are to “glassless pathology” and other digital innovations that could transform the field.In this episode we cover:Richard's BackgroundWith an eclectic background spanning English literature, medical school, research, and even a tech startup, Richard brings unique expertise in digital pathology. At UC Davis, he's pioneering new microscopy methods like MUSE and FIBI that enable imaging thick tissue sections without slides or stains.Pigeon ResearchYou may also know Richard for his famously viral research training pigeons to detect cancer in pathology slides. As he explains, “Pigeons have the skills to tell...tiny, tiny pattern differences” critical for pathological diagnosis. This project brought fun and creativity to his lab, even as they push new frontiers in glassless pathology.Histolix and Glassless PathologyHis company Histolix is commercializing the glassless pathology approach, which Richard envisions bringing pathology on par with radiology's direct-to-digital workflow. Their validation study already achieved 97% concordance between glassless and standard H&E reads. As Richard explains, these techniques “open up the possibility for rapid intraoperative diagnosis without freezing or sectioning.”Digital Pathology InnovationCombined with AI, innovations like these could automate workflow steps like staining, analysis, and prioritization. However, as their recent paper explores, AI does pose risks. Richard believes we must tread carefully, using human oversight and judgment to guide implementation. Still, he sees great potential to augment diagnostics with computational tools.ConclusionThere's no better guide to exploring these frontiers than Richard. Tune into the full conversation using the link above for an insightful tour of digital pathology's cutting edge. Check Histolix for the latest on their research, and access key publications from Richard's lab through the links below. Where will you help take pathology next?THIS EPISODES RESOURCESHistolix websiteA Pilot Validation Study Comparing Fluorescence-Imitating Brightfield Imaging, A Slide-Free Imaging Method, With Standard Formalin-Fixed, Paraffin-Embedded Hematoxylin-Eosin-Stained Tissue Section Histology for Primary Surgical Pathology DiagnosisPocket MUSE: an affordable, versatile and high-performance fluorescence microscope using smartphone. AI in Pathology: What could possibly go wrong?Pigeons (Columba livia) as Trainable Observers of Pathology and Radiology Breast Cancer Images. Support the showBecome a Digital Pathology Trailblazer and See you inside the club: Digital Pathology Club Membership
Hi friends, this is Dr. Michael Williams and welcome to another episode of the diversify in path podcast. This podcast explores how investing in diversity can lead to a high return of investment in pathology and laboratory medicine by learning from the knowledge and experiences of diverse voices within in our field. My next guest is Dr. Andrea DeyrupDr. Deyrup received her undergraduate degree from Princeton University in the Department of Ecology and Evolutionary Biology in 1991 before joining the University of Chicago for her Ph.D. (Pathology, 1997), M.D. (2000) and residency (Anatomic Pathology, 2000-2003). She completed her formal training in soft tissue pathology at Emory with Dr. Sharon Weiss and joined the faculty there in 2004. She has published extensively in the field of soft tissue and bone pathology.Since 2015, Dr. Deyrup's career has focused on medical education. At that time, she joined the faculty of the Duke Pathology Department as Course Director of the first-year medical school pathology course; in January of 2019, she was named the Director of Undergraduate Medical Education for the Pathology Department. She also serves on the Undergraduate Medical Education Council for the Association of Pathology Chairs, participated in the 2020-21 Duke Teaching for Equity Fellows Program and was a member of the Duke School of Medicine Health Professions Anti-Racism Task Force. Dr. Deyrup is one of the co-editors of the new Robbins Pathology textbook, Essential Pathology and of the upcoming 11th edition of Robbins Basic Pathology. Dr. Deyrup is actively committed to antiracism efforts and to improving discussion of health disparities in medical education Twitter: @ATDeyrupMDPhDYoutube: https://www.youtube.com/channel/UC_C1NfzSg96ybalbjl8XydAWebsite: https://www.pathologycentral.org/
Kicking it off with the Buzz Question about the omicron variant. At a stop in the central valley, Gov. Newsom states that he is confident in the state's plan to continue vaccinations and manage COVID will keep us from another shutdown heading into the holidays. A word from Dr. Bill Morice, President of Mayo Clinic Labs and the Chair of Lab Medicine and Pathology Department, discusses the latest variant. CA's Department of Water Resources has announced that valley farmers will get none of their water allocation in 2022 and municipal water users will get enough to meet minimum health and safety demands. Listeners comment. See omnystudio.com/listener for privacy information.
Kicking it off with the Buzz Question about the omicron variant. At a stop in the central valley, Gov. Newsom states that he is confident in the state's plan to continue vaccinations and manage COVID will keep us from another shutdown heading into the holidays. A word from Dr. Bill Morice, President of Mayo Clinic Labs and the Chair of Lab Medicine and Pathology Department, discusses the latest variant. CA's Department of Water Resources has announced that valley farmers will get none of their water allocation in 2022 and municipal water users will get enough to meet minimum health and safety demands. Listeners comment. See omnystudio.com/listener for privacy information.
Digital pathology refers to everything from a static image of a slide to a real-time broadcast image. So, what do laboratory professionals mean when we talk about using digital pathology? What infrastructure is necessary beyond the scanners themselves? And what is driving the adoption of digital pathology tools? On this episode of Inside the Lab, Dr. Dan Milner and guest host Dr. Joe Sirintrapun, MD, Director of Pathology Informatics at Memorial Sloan Kettering Cancer Center, are joined by Dr. Orly Ardon, MD, Science Manager for Digital Pathology Diagnostics at Memorial Sloan Kettering Cancer Center's Pathology Department, Dr. Matthew Hanna, MD, Director of Digital Pathology Informatics at Memorial Sloan Kettering Cancer Center, and Dr. Jochen Lennerz, MD, Associate Chief of Pathology and Medical Director of the Center for Integrated Diagnostics at Massachusetts General Hospital, to discuss digital pathology. Our panelists explore the barriers to widespread implementation of whole slide imaging, and discuss factors a laboratory should consider before investing in a particular digital pathology system. They explain how digital pathology can benefit laboratory professionals in microbiology, cytology, and hematopathology and describe how the pandemic accelerated the adoption of digital tools. Listen in for insights on incentivizing vendors to facilitate interoperability and learn how AI technology is driving the use of digital pathology. Topics Covered· What pathologists and laboratory professionals mean by the phrase "digital pathology"· Barriers to widespread adoption of whole slide imaging systems· Important factors a laboratory should consider before investing in a particular digital pathology system· How digital pathology can benefit laboratory professionals in areas like microbiology, cytology, and hematopathology· Why decentralized, rural laboratories should consider using digital pathology· How commercially available artificial intelligence drives the adoption of digital pathology· Lessons learned around the adoption of a digital pathology platform for clinical use Connect with ASCPASCPASCP on Twitter Connect with Dr. ArdonDr. Ardon on LinkedInDr. Ardon on Google Scholar Connect with Dr. HannaDr. Hanna at Memorial Sloan KetteringDr. Hanna on TwitterDr. Hanna on PubMed Connect with Dr. Lennerz Dr. Lennerz at Massachusetts GeneralDr. Lennerz on LinkedInConnect with Dr. Milner & Dr. Sirintrapun Dr. Milner on TwitterDr. Sirintrapun on Twitter Resources Inside the Lab in the ASCP Store
The November 2018 issue of the Journal of Applied Laboratory Medicine published a Special Report by Drs. Ann Gronowski and Carey-Ann Burnham at the Washington University School of Medicine in St. Louis that discussed the formation of a professional development group for women in the pathology department of a major medical school. Dr. Gronowski, who is Professor in the departments of pathology and immunology, and obstetrics and gynecology, joins us in this podcast.
In this CAPcast, Dr. Donald Karcher will discuss how the current political climate is impacting key advocacy issues for pathologists. Dr. Karcher is a Chair of the Pathology Department at George Washington University Hospital in Washington, DC, as well as the Chair of the CAP’s Council on Government and Professional Affairs. He is also a member of the CAP Board of Governors.
Dr. Politi is an Associate Professor in the Pathology Department at Yale School of Medicine. In this episode of Beer with a Scientist, she'll teach us about cancer— what it is, how it tricks our best defences into ignoring it and what scientists are doing to stop it.
Dr Lisa Lee is an Associate Professor at the Department of Cell and Developmental Biology, School of Medicine, University of Colorado in the United States Lisa joins me for a wide-ranging chat about her career path into anatomy education and her work in the Pathology Department at Creighton University. We also discuss her recent anatomy scholarship at the University of Colorado where she teaches histology, embryology and gross anatomy using innovative virtual reality resources, and her recent work on gender bias with TEL resources. Here are the links to the various papers and resources we discussed: Leeshistology AAA Virtual Microscope Database and follow using @VMDatabase Lippincotts Pocket Histology Series A Primer for Maximizing Your Professional and Academic Footprint by Utilizing Social Media Dissecting the voice: Health professions students' perceptions of instructor age and gender in an online environment and the impact on evaluations for faculty You can follow Lisa using the twitter handle: @LLCoolProf To continue the conversation use: #AnatPodcast Follow: @AnatEducPodcast Visit: anatomypodcast.co.uk for more information The Anatomy Education Podcast is supported by the American Association of Anatomists. For information about upcoming events, membership details and much more, visit www.anatomy.org.
Background. Posttransplantation lymphoproliferative diseases (PTLD) are mainly Epstein-Barr virus (EBV)-associated disorders of B-cell origin. Due to the rarity of monomorphic T-cell PTLD (T-PTLD), knowledge about pathogenesis, risk factors, therapy, and prognosis relies predominantly on case reports and small series. Therefore, we aimed to provide an overview and a retrospective analysis of this rare PTLD subtype. Methods. We analyzed all available articles on T-PTLD in the PubMed database as well as in our own databases (Institute of Pathology/Department of Paediatric Haematology and Oncology, Hannover Medical School) from 1988 to 2010. Reevaluated parameters were gender, age, transplanted organ, immunosuppressant regimen, time between transplantation and T-PTLD manifestation, T-PTLD subtype, virus positivity, localization, therapy, and follow-up. Results. A total of 163 cases were evaluated. We found that hematopoietic stem cell transplantation was associated with early-onset T-PTLD, whereas late onset occurred after immunosuppression with steroids and azathioprine without administration of calcineurin inhibitors. The major independent favorable prognostic factors were T-PTLD of the large granular lymphocytic leukemia subtype, young age, and a combination of radiotherapy/radiochemotherapy and reduced immunosuppression, whereas the hepatosplenic T-cell lymphoma subtype and cases with involvement of bone marrow, the central nervous system, or graft had an adverse prognosis. Conclusion. T-PTLD is a heterogeneous group of different aberrant T-cell proliferations and represents a significant complication following transplantation, showing a uniformly poor prognosis.
Four presenters of new medical technologies are today's featured guests. Benjamin Rhymer (a Registered Cardiovascular Invasive Specialist with the Cath Lab) describes how surgeries are performed inside the human heart without opening the chest using manipulation devices mounted on the end of long flexible catheters; he also discusses intravascular ultrasound cameras, and fluoroscopy. Laura Goldberg and Michelle Mekscer (of the Pathology Department at Aiken Regional Medical Centers Laboratory) describe how removed tissues are being examined microscopically in real time by specialists hundreds of miles away by sending live images from the microscope in the operating room to the specialist through the Internet. Doctor Chad Leverett (Associate Professor of Chemistry at USCA who is also a nanotechnology scientist working with the USC Nano Center in Columbia SC) describes his and the university's work in nanotechnology: including nanosensors, nanostructures and nanotechnology in medicine. He also explains the uses and technology of an infrared optical spectrometer which provides an instantaneous readout on a laptop computer of a sample's complete chemical and molecular composition. Hosted by Stephen Euin Cobb, this is the November 10, 2010 episode of The Future And You. [Running time: 32 minutes] These interviews were taped from the exhibition floor of the 2010 Business, Innovation and Technology Expo which was held on the campus of the University of South Carolina on July 17 2010.