Specialized agency of the United Nations
POPULARITY
Categories
My conversation with Dr Emanuel begins at about 34 minutes Subscribe and Watch Interviews LIVE : On YOUTUBE.com/StandUpWithPete ON SubstackStandUpWithPete Stand Up is a daily podcast. I book,host,edit, post and promote new episodes with brilliant guests every day. This show is Ad free and fully supported by listeners like you! Please subscribe now for as little as 5$ and gain access to a community of over 750 awesome, curious, kind, funny, brilliant, generous soul In Eat Your Ice Cream, renowned health expert Dr. Ezekiel J. Emanuel argues that life is not a competition to live the longest, and that "wellness" shouldn't be difficult; it should be an invisible part of one's lifestyle that yields maximum health benefits with the least work Ezekiel J. Emanuel, MD, PhD, is the Vice Provost for Global Initiatives, the Co-Director of the Healthcare Transformation Institute, and the Diane v.S. Levy and Robert M. Levy University Professor at the University of Pennsylvania Perelman School of Medicine. Emanuel is an oncologist and world leader in health policy and bioethics. He is a Special Advisor to the Director General of the World Health Organization, Senior Fellow at the Center for American Progress, and member of the Council on Foreign Relations. He was the founding chair of the Department of Bioethics at the National Institutes of Health and held that position until August of 2011. From 2009 to 2011, he served as a Special Advisor on Health Policy to the Director of the Office of Management and Budget and National Economic Council. In this role, he was instrumental in drafting the Affordable Care Act (ACA). Emanuel also served on the Biden-Harris Transition Covid Advisory Board. Dr. Emanuel is the most widely cited bioethicist in history. He has over 350 publications and has authored or edited 15 books. His recent publications include the books Which Country Has the World's Best Health Care (2020), Prescription for the Future (2017), Reinventing American Health Care: How the Affordable Care Act Will Improve our Terribly Complex, Blatantly Unjust, Outrageously Expensive, Grossly Inefficient, Error Prone System (2014) and Brothers Emanuel: A Memoir of an American Family (2013). In 2008, he published Healthcare, Guaranteed: A Simple, Secure Solution for America, which included his own recommendations for health care reform. Dr. Emanuel regularly contributes to the New York Times, the Washington Post, the Wall Street Journal, The Atlantic, and often appears on BBC, NPR, CNN, MSNBC and other media outlets. He has received numerous awards including election to the National Academy of Medicine, the American Academy of Arts and Sciences, the Association of American Physicians, and the Royal College of Medicine (UK). He has been named a Dan David Prize Laureate in Bioethics, and is a recipient of the AMA-Burroughs Wellcome Leadership Award, the Public Service Award from the American Society of Clinical Oncology, Lifetime Achievement Award from the American Society of Bioethics and Humanities, the Robert Wood Johnson Foundation David E. Rogers Award, President's Medal for Social Justice Roosevelt University, and the John Mendelsohn Award from the MD Anderson Cancer Center. Dr. Emanuel has received honorary degrees from Icahn School of Medicine at Mount Sinai, Union Graduate College, the Medical College of Wisconsin, and Macalester College. In 2023, he became a Guggenheim Fellow. Dr. Emanuel is a graduate of Amherst College. He holds a M.Sc. from Oxford University in Biochemistry, and received his M.D. from Harvard Medical School and his Ph.D. in political philosophy from Harvard University. On YOUTUBE.com/StandUpWithPete ON SubstackStandUpWithPete Listen rate and review on Apple Podcasts Listen rate and review on Spotify Pete On Instagram Pete on Blue Sky Pete on Threads Pete on Tik Tok Pete on Twitter Pete Personal FB page Stand Up with Pete FB page All things Jon Carroll Gift a Subscription https://www.patreon.com/PeteDominick/gift Send Pete $ Directly on Venmo
Depo-Provera was approved in 1992 by U.S. regulators. About 1 in 4 sexually active women in the United States have used the shot at some point, according to the U.S. Centers for Disease Control and Prevention (CDC). Meningiomas are common intracranial tumors with a female predominance. In fact, they are the most common primary brain tumor in women, with an incidence of approximately 12.76 per 100,000 in the general female population. The vast majority of these tumors are benign (World Health Organization [WHO] grade 1) while 15% to 20% of these tumors can behave atypically (WHO grade 2) and rarely, in 1% to 2% of cases, these tumors can be malignant (WHO grade 3). We covered the relationship between Depo-Provera, as a contraceptive agent, and brain meningiomas back in March 2024. With the increase in data, the ACOG released a patient centered counseling tool titled, “Counseling Patients on Birth Control Injection and Meningioma”. The most recent update on this story comes from the FDA, which has granted a medication label change to Depo-Provera (Pfizer) warning of this association. Even though association does not prove causation, the association between depo and meningiomas seems strong (with new data from the US). Does this warning extend to other progestins? Listen in for details. 1. https://podcasts.apple.com/us/podcast/dr-chapas-obgyn-clinical-pearls/id1412385746?i=10006508795722. ACOG's “Counseling Patients on Birth Control Injection and Meningioma” 3. https://www.statnews.com/pharmalot/2025/12/17/fda-pfizer-contraception-cancer-preemption-depoprovera/4. Xiao T, Kumar P, Lobbous M, et al. Depot Medroxyprogesterone Acetate and Risk of Meningioma in the US. JAMA Neurology. 2025;82(11):1094-1102. doi:10.1001/jamaneurol.2025.3011.5. de Dios E, Näslund O, Choudhry M, et al.Prevalence and Symptoms of Incidental Meningiomas: A Population-Based Study.Acta Neurochirurgica. 2025;167(1):98. doi:10.1007/s00701-025-06506-7.6. Schaff LR, Mellinghoff IK.Glioblastoma and Other Primary Brain Malignancies in Adults: A Review. JAMA. 2023;329(7):574-587. doi:10.1001/jama.2023.0023.7. BMJ 2024; 384 doi: https://doi.org/10.1136/bmj-2023-078078 (Published 27 March 2024) Cite this as: BMJ 2024;384:e078078
Naveed Akram, the surviving suspect of the Bondi Beach mass shooting, is charged with fifty-nine offences including fifteen counts of murder, as well as committing a terrorist act. He was charged at his bedside in hospital, after coming out of a coma. His father, Sajid Akram, was shot dead by police during the attack, which targeted Australia's Jewish community at an event celebrating the first night of Hanukkah. Also: the head of the World Health Organisation calls for the immediate release of health workers who are believed to be detained in south-western Sudan. The authorities in the Indian capital, Delhi, roll out strict measures to curb air pollution, that has been in the severe category for the past few days. The tiny mountain kingdom of Bhutan has announced it will spend a billion dollars of the country's reserves to build what it's calling a "mindfulness city." And scientists warn that nature photographers are causing irreparable harm to the endangered Galaxy Frog in India. The Global News Podcast brings you the breaking news you need to hear, as it happens. Listen for the latest headlines and current affairs from around the world. Politics, economics, climate, business, technology, health – we cover it all with expert analysis and insight. Get the news that matters, delivered twice a day on weekdays and daily at weekends, plus special bonus episodes reacting to urgent breaking stories. Follow or subscribe now and never miss a moment. Get in touch: globalpodcast@bbc.co.uk
The head of the World Health Organisation has called for the immediate and unconditional release of health workers who are believed to be detained in south- western Sudan. The Sudanese Doctors Network fears about 19,000 people could be held by Sudan's paramilitary Rapid Support Forces (RSF) in Nyala, South Darfur. We hear from a journalist there about the situation. Also in the programme: The Secret trial of a Chinese General who defied orders to crush the pro-democracy protests in Tiananmen Square; and Hollywood star Timothée Chalamet on his latest film.(Photograph: Darfuri children in Tine refugee camp. Credit: Reuters)
Obesity affects more than 1 billion people worldwide and is recognized by the World Health Organization as a chronic, relapsing disease. WHO recently published a guideline in JAMA on the use and indications of GLP-1 therapies for the treatment of #obesity in adults. Francesca Celletti, MD, PhD, and Ezekiel Emanuel, MD, PhD, join JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss. Related Content: World Health Organization Guideline on the Use and Indications of Glucagon-Like Peptide-1 Therapies for the Treatment of Obesity in Adults
“Too far, too fast?”In this sixth episode, Sarah Harrison, Director of the MHPSS Hub, and Dan Amias, Senior Innovation Learning Adviser at Elrha, speaks with Mercy Githara, MHPSS Manager at the Kenya Red Cross Society, and Anne de Graaf, Technical Officer at the World Health Organization (WHO) about two chatbots: STARS, a non-AI chatbot developed by WHO, and Chat Care, an AI chatbot being deployed in Kenya by the Red Cross.Key resources for practitioners:Kenya Red Cross Society: Chat Care, AI Powered Mental Health Chatbot WHO: Doing What Matters in Times of Stress evidence based self-help guide WHO: STARS chatbot for more information contact psych_interventions@who.int Red Cross Digital MHPSS pledge: Leveraging and facilitating technology-empowered pathways MHPSS Hub resources on Suicide prevention:Find infographics, videos, podcasts, guides and tools on suicide prevention Read more about the research:STARS chatbot (non-AI): de Graaff A.M, et al. Evaluation of a Guided Chatbot Intervention for Young People in Jordan: Feasibility Randomized Controlled Trial JMIR Ment Health Keyan, D., et al. The development of a World Health Organization transdiagnostic chatbot intervention for distressed adolescents and young adults. Akhtar, A., et al. Scalable Technology for Adolescents and Youth to Reduce Stress in the Treatment of Common Mental Disorders in Jordan: Protocol for a Randomized Controlled Trial. Karim Chatbot: Madianou, M. Nonhuman humanitarianism: when “AI for good” can be harmful. Information, Communication & SocietyTorous, J. et al. Assessing generative artificial intelligence for mental health, The Lancet.Spencer SW, Masboungi C. Enabling access or automating empathy? Using chatbots to support GBV survivors in conflicts and humanitarian emergencies, International Review of the Red Cross. Developing digital MHPSS resources:Reach out to the MHPSS Hub: mhpsshub@rodekors.dk or Elrha: info@elrha.org for collaboration on developing digital MHPSS approaches.Evidence from the Frontline: Mental Health in Crisis-Affected Contexts is a six-episode mini-series produced in collaboration between the MHPSS Hub and Elrha, designed for practitioners working in humanitarian and crisis contexts, the series highlights impactful interventions and practical insights from experts in the field.
This week on The Broski Report, Fearless Leader Brittany Broski talks about The Beatles, her dream Christmas decor, and this year's Christmas List! Watch The Broski Report AD FREE: https://patreon.com/broskireport The OFFICIAL Songs of The Week Playlist: https://open.spotify.com/playlist/3ULrcEqO2JafGZPeonyuje?si=061c5c0dd4664f01
The World Health Organisation recommends all pregnant women should have at least one ultrasound before six months. However, only half of women do in sub-Saharan Africa. This week we visit Kenya to see how portable ultrasound devices are flagging up any issues early. And how AI could overcome the barrier of not having enough trained midwives on the ground.People Fixing The World from the BBC is about brilliant solutions to the world's problems. We release a new edition every Tuesday. We'd love you to let us know what you think and to hear about your own solutions. You can contact us on WhatsApp by messaging +44 8000 321721 or email peoplefixingtheworld@bbc.co.uk. And please leave us a review on your chosen podcast provider.Presenter: Myra Anubi Producers: Calvin Manika, Claire Bates Editor: Jon Bithrey Sound mix: Andrew Mills(Image: A midwife gives a pregnant woman an ultrasound scan, BBC/Davis Ojiambo)
This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor unpack the biggest GLP-1 headlines from around the world—from the World Health Organization's first-ever GLP-1 obesity guidelines to access battles, brain research, and the coming wave of generics and new meds.Dr. Cooper explains what the WHO's move really means for patients, why long-term treatment matters, and how policy decisions in places like California and India could reshape who actually benefits from these breakthroughs. This isn't hype—it's metabolic medicine, health-system reality, and grounded hope.Key Questions AnsweredWhy is the WHO's new guidance on GLP-1s for obesity such a historic turning point?What does it mean to treat obesity as a chronic, relapsing disease—not a willpower problem?Why do GLP-1s usually need to be taken long term, and how is that similar to blood pressure or cholesterol meds?How should GLP-1s be paired with metabolic care—fueling, sleep, movement, and real clinical oversight?What did the “stone cold negative” Alzheimer's trials show—and why are addiction trials still promising?How could India's launch of Ozempic and future generics impact global pricing and access?What new GLP-1 and metabolic drugs are on the horizon (like orforglipron, higher-dose oral semaglutide, and GLP-1/amylin combos)?Key TakeawaysWHO is catching up to the science. Obesity is affirmed as a chronic, relapsing disease that deserves pharmacologic treatment—not “eat less, move more” lectures or moral judgment.Long-term meds are the rule, not the exception. Stopping GLP-1s usually leads to weight and risk factors returning, just like stopping blood-pressure meds. That's physiology, not failure.Behavior ≠ blame. WHO calls for pairing GLP-1s with “behavioral” care—but Dr. Cooper reframes this around fueling, sleep, and supported habits, not deprivation or diet culture.Access is the battleground. Even as WHO elevates GLP-1s, programs like California's Medi-Cal are cutting coverage for obesity, a move Dr. Cooper calls penny-wise and pound-foolish given the downstream costs of diabetes and cardiovascular disease.Brain outcomes are nuanced. Large oral semaglutide trials failed to slow Alzheimer's, but GLP-1s (and other obesity meds) still show promise for addiction by modulating reward pathways and the “internal drug factory” (POMC).Global markets are shifting. India's huge population, looming Ozempic patent expirations, and emerging generics could eventually drive prices down—especially as more manufacturers compete.New meds may expand options. Orforglipron (a small-molecule oral GLP-1), higher-dose oral semaglutide, and a weekly GLP-1/amylin combo could bring more flexible, powerful, and potentially more affordable tools.Dr. Cooper's Actionable TipsThink of obesity treatment like any chronic disease: long-term, medical, and individualized—not a short-term “diet.”If you're using a GLP-1, pair it with real metabolic care: consistent fueling (not under-eating), good sleep, and appropriately fueled exercise.Be cautious with “cheap” or unsanctioned online GLP-1 options—especially if you're being squeezed out of coverage. Safety and oversight matter.Remember there are other evidence-based obesity meds beyond GLP-1s; if you can't tolerate or access one class, ask your clinician about alternatives.Notable Quote“Your metabolism is a lifelong issue. It's not a headache.”— Andrea TaylorLinks & ResourcesPodcast Home: Fat Science Podcast Website – https://fatsciencepodcast.com/ Cooper Center for Metabolism & Fat Science Episodes: https://coopermetabolic.com/podcast/ Resources and education from Dr. Cooper: https://coopermetabolic.com/resources/ Submit a Show Question: questions@fatsciencepodcast.comDr. Cooper direct show email: dr.c@fatsciencepodcast.com*Fat Science is your source for breaking diet myths and advancing the science of true metabolic health. No diets, no agendas—just science that makes you feel better.
Weight-loss injections have become a major talking point, from Hollywood celebrities to TikTok influencers.Originally developed to treat diabetes, these medications were later found to help people shed a lot of weight - a discovery that has rapidly expanded their global use. The World Health Organization has now released its first-ever guidance on prescribing them for obesity.South Africa recently became the first country in Africa to formally approve one version of these drugs for weight loss, and access is slowly spreading across the continent.We follow a Kenyan woman's experience using the injections and we hear from a South African doctor who explains how they work - and what the latest medical research reveals so far.
It's estimated that as many as 10 per cent of adults in Canada use a GLP-1 type drug like Ozempic. The prescription medicine is used for type 2 diabetes management and increasingly prescribed off-label for weight loss. And this month, for the first time, the World Health Organization has conditionally recommended GLP-1 drugs for the long-term treatment of obesity.But while these drugs have been called a game-changing tool to manage a complex and stigmatized health condition, there's also a lot of questions about the potential negative impact.With Ozempic's patent set to expire soon in Canada, and more affordable generic options about to hit the market, a lot more people you know could end up on a weight-loss drug.Today we bring you the rise and risks of GLP-1s with help from Dylan Scott. He is a Senior Correspondent at Vox who covers health.For transcripts of Front Burner, please visit: https://www.cbc.ca/radio/frontburner/transcripts
Schizophrenia is a mental disorder characterised by impairments in the way reality is perceived with associated changes in behaviour. We cover the symptoms of Schizophrenia (with delusion types), including the DSM-5 criteria for diagnosis, as well as Schizophrenia treatment. PDFs available here: https://rhesusmedicine.com/pages/psychiatryConsider subscribing (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Patreon: https://www.patreon.com/rhesusmedicineBuy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 What is Schizophrenia?0:28 Schizophrenia Symptoms - Positive Symptoms2:28 Schizophrenia Symptoms - Negative Symptoms2:58 Schizophrenia Symptoms - Cognitive Symptoms 3:49 Schizophrenia Diagnosis / Diagnostic DSM 5 Criteria 5:08 Schizophrenia Causes / Pathophysiology 5:53 Schizophrenia Risk Factors & Epidemiology 7:00 Schizophrenia Treatment LINK TO SOCIAL MEDIA: https://www.instagram.com/rhesusmedicine/ReferencesNational Institute of Mental Health (NIMH), 2025. Schizophrenia. [online] Available at: https://www.nimh.nih.gov/health/topics/schizophrenia.World Health Organization (WHO), 2025. Schizophrenia. [online] Available at: https://www.who.int/news-room/fact-sheets/detail/schizophrenia.National Alliance on Mental Illness (NAMI), 2025. Schizophrenia. [online] Available at: https://nami.org/About-Mental-Illness/Mental-Health-Conditions/Schizophrenia.Wikipedia, 2025. Schizophrenia. [online] Available at: https://en.wikipedia.org/wiki/Schizophrenia.Medscape, 2025. Schizophrenia: Symptoms, Causes & Treatment Options. [online] Available at: https://emedicine.medscape.com/article/288259-overview.Symptom Media, 2025. Schizophrenia Delusions: Definition, Types, and Treatments. [online] Available at: https://symptommedia.com/delusions-associated-with-schizophrenia-ce-course-preview/.Psycom, 2025. Schizophrenia: Symptoms, Causes, Diagnosis, Treatment. [online] Available at: https://www.psycom.net/schizophrenia.StatPearls, 2025. Schizophrenia. [online] Available at: https://www.ncbi.nlm.nih.gov/books/NBK539864/.Disclaimer: Please remember this podcast and all content from Rhesus Medicine is for educational and entertainment purposes only and is not a guide to diagnose or to treat any form of condition. The content is not to be used to guide clinical practice and is not medical advice. Please consult a healthcare professional for medical advice.
Tired of eating the same boring veggies every week? Let's talk about nutrient diversity—the health hack nobody's buzzing about but should be! It's not about being perfect or following strict rules; it's about bringing more color, flavor, and fun to your plate while feeling amazing.In this episode of Salad With a Side of Fries, host Jenn Trepeck explores why micronutrients matter just as much as macronutrients. Learn how eating a variety of colored vegetables, embracing seasonal eating, and experimenting with different vitamins and minerals can improve gut health, support immune function, and enhance healthy aging. Hear practical strategies for adding dietary variety without complicating your routine, plus why the holidays offer a perfect opportunity for nutrient-rich foods.What You Will Learn in This Episode:✅ Why nutrient diversity and micronutrients are just as important as tracking your macros, and how eating a limited variety of foods puts your body into survival mode, affecting everything from energy levels to bone health and metabolic function.✅ The power of eating the rainbow—how different food colors indicate specific vitamins and minerals like iron, folate, beta-carotene, and antioxidants, and why incorporating plant-based foods with various phytochemicals supports immune support, digestive health, and reduces chronic disease risk.✅ Practical strategies to increase dietary variety without overwhelm, including shopping at farmers' markets, using frozen organic vegetables, cooking with global spices, and creating rainbow meals that make seasonal eating easy and affordable.✅ How the holiday season offers a hidden opportunity for nutrient diversity through festive foods you don't normally eat, and why developing a sense of culinary adventure helps improve gut microbiome diversity and overall wellness.The Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.TIMESTAMPS: 00:00 Introduction to nutrient diversity as the overlooked health tool and how micronutrient variety impacts satiety, energy levels, and overall wellness during the holiday season06:59 Understanding micronutrients versus macronutrients and why vitamins and minerals deserve more attention in wellness conversations than just tracking macros08:48 The World Health Organization recommendations for daily fruit and vegetable intake10:12 Why we're not getting nutrient diversity: the food industry focuses on taste over nutrition, lack of crop rotation, and produce picked before ripening loses connection to soil nutrients14:42 Three crops (rice, wheat, maize) provide over half of the world's plant-based calories, yet lack the phytochemicals and bioactive compounds needed for optimal health16:46 Research linking dietary variety to reduced type 2 diabetes risk, lower metabolic syndrome, improved cognitive function, and better gut microbiome diversity18:26 Eating the rainbow: how different food colors signal specific nutrients—green for iron and folate, orange for beta-carotene, red and purple for antioxidants22:39 Cravings and listening to our bodies33:17 Practical tips for becoming a "varietarian," including organic options, seasonal eating, using global spices, and shopping at farmers' markets for inspiration38:35 Using frozen organic vegetables for affordability and convenience while maintaining nutrient-rich variety throughout the week without food wasteKEY TAKEAWAYS:
The Centers for Disease Control is changing its recommendations for when to give babies the hepatitis B vaccine and the World Health Organization has weighed in on GLP-1 weight loss drugs.
This is a free preview of a paid episode. To hear more, visit ianmsc.substack.comDr. Jay Bhattacharya is the director of the National Institutes of Health, the organization formerly run by Dr. Francis Collins and Dr. Anthony Fauci. But Dr. Bhattacharya's importance extends much further than “just” NIH. And his appointment there under the second Donald Trump administration marked a dramatic about-face for an organization that was instrumental in creating many of the issues and problems we faced as a society during the pandemic.Dr. Bhattacharya was one of the authors of the Great Barrington Declaration in 2020. That paper contained a blueprint for focused protection during the COVID-19 pandemic. Instead of locking down all society, Bhattacharya and his co-authors wrote, we should look to protect the most vulnerable. That's been proven prophetic, as the harms from lockdowns far exceeded any benefits.He also conducted a study in Silicon Valley early on in the lockdowns that identified COVID was far more prevalent in the community than people realized. That meant the virus was also far less deadly than organizations like the World Health Organization had suggested. He was skeptical about the efficacy of cloth masks, advocated for opening schools, and participated in a roundtable hosted by Florida Gov. Ron DeSantis in 2021 that illustrated how ineffectual the Anthony Fauci-doctrine had been. Around that same time, Bhattacharya also spoke out against vaccine mandates and other abuses, which decreased public confidence and trust in vaccines.In short, he was a voice of sanity in a sea of absurdity, proven right about nearly every pandemic-related policy. For his efforts, he was demonized, labeled, censored, and targeted by Collins and Fauci in emails. I had the exclusive opportunity to ask him about many of these issues, and what he's bringing to NIH that his predecessors didn't.Unmasked is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.
By Susanna Ray Microsoft AI is entering a new phase, one defined by real-world impact. After several years of experimentation, 2026 is shaping up to be the year AI evolves from instrument to partner, transforming how we work, create and solve problems. Across industries, AI is moving beyond answering questions to collaborating with people and amplifying their expertise. This transformation is visible everywhere. In medicine, AI is helping close gaps in care. In software development, it's learning not just code but the context behind it. In scientific research, it's becoming a true lab assistant. In quantum computing, new hybrid approaches are heralding breakthroughs once thought impossible. As AI agents become digital colleagues and take on specific tasks at human direction, organisations are strengthening security to keep pace with new risks. The infrastructure powering these advances is also maturing, with smarter, more efficient systems. These seven trends to watch in 2026 show what's possible when people join forces with AI. AI will amplify what people can achieve together Aparna Chennapragada, Microsoft's chief product officer for AI experiences, sees 2026 as a new era for alliances between technology and people. If recent years were about AI answering questions and reasoning through problems, the next wave will be about true collaboration, Chennapragada says. "The future isn't about replacing humans," she says. "It's about amplifying them." AI agents are set to become digital coworkers, she says, helping individuals and small teams punch above their weight. Chennapragada envisions a workplace where a three-person team can launch a global campaign in days, with AI handling data crunching, content generation and personalisation while humans steer strategy and creativity. She predicts organisations that design for people to learn and work with AI "will get the best of both worlds," helping teams tackle bigger creative challenges and deliver results faster. Her advice for professionals: don't compete with AI, but focus on learning how to work alongside it. The coming year, she says, "belongs to those who elevate the human role, not eliminate it." AI agents will get new safeguards as they join the workforce AI agents will proliferate in 2026 and play a bigger role in daily work, acting more like teammates than tools, says Vasu Jakkal, corporate vice president of Microsoft Security. As organisations rely on these agents to help with tasks and decision-making, building trust in them will be essential, Jakkal says - starting with security. "Every agent should have similar security protections as humans," she says, "to ensure agents don't turn into 'double agents' carrying unchecked risk." That means giving each agent a clear identity, limiting what information and systems it can access, managing the data it creates and protecting it from attackers and threats, Jakkal says. Security will become ambient, autonomous and built-in, she says, not something added on later. In addition, as attackers use AI in new ways, defenders will use security agents to spot those threats and respond faster, she says. "Trust is the currency of innovation," Jakkal says, making these shifts vital to helping organisations keep up with new risks as AI continues to become more central to how work gets done. AI is poised to shrink the world's health gap AI in healthcare is marking a turning point, says Dominic King, vice president of health at Microsoft AI. "We'll see evidence of AI moving beyond expertise in diagnostics and extending into areas like symptom triage and treatment planning," King says. "Importantly, progress will start to move from research settings into the real world, with new generative AI products and services available to millions of consumers and patients." That shift matters because access to care is a global crisis. The World Health Organisation projects a shortage of 11 million health workers by 2030 - a gap that leaves 4.5 billi...
This week on The Broski Report, Fearless Leader Brittany Broski recaps Wuthering Heights by Emily Brontë, discusses Studio Ghibli, and recounts seeing Robert Downey Jr. Watch The Broski Report AD FREE: https://patreon.com/broskireport The OFFICIAL Songs of The Week Playlist: https://open.spotify.com/playlist/3ULrcEqO2JafGZPeonyuje?si=061c5c0dd4664f01
Dialogues is a series from the Global Health Matters podcast where we bring you interviews featuring fresh perspectives on global health issues. The goal of each Dialogues episode is to break through the echo chambers that exist in global health through in-depth, thoughtful conversations. In this episode of Dialogues, we take a deeper look at stigma and how often unconsciously we as global health professionals may be perpetuating it. Host Garry Aslanyan is joined by Alex Brewis, Regents and Presidents Professor in the School of Human Evolution and Social Change at Arizona State University, where she previously founded and directed the Centre for Global Health. As an anthropologist, Alex brings both rich field experience and deep academic insight, helping us reflect on the intentional and unintentional impacts of our global health efforts. Related episode documents, transcripts and other information can be found on our website.Subscribe to the Global Health Matters podcast newsletter. Follow us for updates:@TDRnews on XTDR on LinkedIn@ghm_podcast on Instagram@ghm-podcast.bsky.social on Bluesky Disclaimer: The views, information, or opinions expressed during the Global Health Matters podcast series are solely those of the individuals involved and do not necessarily represent those of TDR or the World Health Organization. All content © 2025 Global Health Matters.
Send us a textCervical cancer is the fourth most common cancer in women globally, according to the World Health Organization. It's preventable and curable as long as it's detected early and managed effectively. Our guest expert for this episode is Salvatore LoCoco, M.D., chair of the School of Medicine's Department of Obstetrics and Gynecology. LoCoco explains what is cervical cancer, which populations are at greatest risk for cervical cancer, screenings, treatment, vaccinations and prevention.
According to the World Health Organization, loneliness is now recognised as a pressing global health threat. Research shows that chronic loneliness carries the same health risk as smoking 15 cigarettes a day and can reduce life expectancy by up to 30 percent. As host Gabby reflects, the festive season can be one of the hardest times of the year for many. While Christmas is sold to us as joyful, warm, and deeply connected, for some it magnifies feelings of isolation instead. A UK survey found that 17% of people feel lonelier during the holidays, even when surrounded by loved ones. The gap between the expectation of celebration and the reality of personal circumstances can intensify sadness, anxiety, and disconnection, making December a particularly heavy month for those already struggling. In this episode — a conversation recorded 18 months ago but more relevant than ever — Gabby speaks with Dr Richard Pile, a GP specialising in lifestyle medicine and cardiology, as well as an author, TEDx speaker, podcaster, mentor, and coach. Together, they explore what loneliness really is, how it manifests not only emotionally but physically, and the subtle ways it can shape our behaviour and daily routines. Dr Richard shares the signs to look out for in ourselves and others, and why nurturing the relationships we already have is so vital. He also offers practical steps for forming new connections, finding like-minded people in our communities, and accessing NHS social prescribers — a free service designed to link people with activities and groups that support wellbeing. As the festive season approaches, Gabby invites listeners to take one small, meaningful action: reach out to someone who might be struggling. A simple message, phone call, or invitation for coffee can make a profound difference. This episode is a reminder that choosing connection over isolation not only eases another person's burden, but strengthens our own sense of belonging. To download the My Possible Self App: https://mypossibleself.app.link/podcast To follow My Possible Self on Instagram: https://www.instagram.com/mypossibleself For more information on Dr Richard Pile and his services: https://feelgoodforlife.uk/ To watch Dr Richard's TedX talk on Loneliness: https://youtu.be/sPsvOd-kwVU? si=dAIYYR_E_ukAhcyg
On today's Good Day Health Show - ON DEMAND…Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) cover a number of topics affecting our health. First up, Doug and Dr. Ken discuss the biggest news stories in the medical world, starting with a discussion on a new treatment for Hereditary Hemorrhagic Telangiectasia (HHT), which is good news for people who suffer from this rare mality, the a proof of concept trial for a new oral therapy for those who deal with severe and recurrent nose bleeds and internal bleeding. In the past, there was no treatment for this, so this is great news and a wonderful step forward for those with HHT. Next up, in Respiratory Syncytial Virus (RSV) news, preventative measures are being tested so that newborns, who are most susceptible, will have a better chance at prevention of acute lung conditions as well as lifelong lung condition of asthma. RSV immunizations can help prevent future children from developing asthma. Then, Doug and Dr. Ken discuss new guidelines for obesity drugs around the world with the World Health Organization (WHO) releasing global guidelines on GLP-1s with key recommendations warning that the medications should not be a stand alone solution. Weight loss drugs should be incorporated into a comprehensive care plan that includes diet and physical activity. WHO also goes into highlighting concerns of global equity, cost and longterm data gaps. The conversation shifts to a study on “beer bellies,” and what it means for heart health and risks, especially in men. Belly fat seems to be linked to changes in heart structure that contribute to heart failure. The heart muscle itself thickens without the heart itself increasing in size, which leads to a smaller volume of blood able to be pumped out of the heart. Another item of obesity has to do with youngsters and the correlation of pre-teens spending too much Tim eon their phones, leading to less time spent with physical activity. This leads to increased risk of depression, obesity, and lower sleep qualities. Other news includes a new treatment for spinal problems, the FDA's granted accelerated approval for a drug treatment for adults with primary IgA Nephropathy, a study on fame being a killer, whether or not shoulder surgery benefits outweigh the risks involved, and new conclusions of a link between acetaminophen (Tylenol being the most famous brand) and whether or not it's causing autism or ADHD in children when the mother used the drug during pregnancy. Website: GoodDayHealthrShow.com Social Media: @GoodDayNetworks
A recent report released by the World Health Organization, stated something that experts in India have been warning about for years: antimicrobial resistance or AMR in our country the report said, “is a serious and escalating threat, with resistance rates among the highest in the world.” The government is taking this threat seriously: it has now brought out National Action Plan on Antimicrobial Resistance (NAP-AMR 2.0) — (2025-29) to combat AMR at all levels. So what is India facing in terms of infections that may not be able to be cured? What sectors does AMR affect outside of hospitals? What are the gaps in the latest AMR plan and how can they be managed? And finally, what can we, as individuals do? Guest: Dr. Abdul Ghafur, Senior Consultant in Infectious Diseases, Apollo Hospital, Chennai, and Coordinator, Chennai Declaration on Antimicrobial Resistance Host: Zubeda Hamid Edited by Sharmada Venkatasubramanian Learn more about your ad choices. Visit megaphone.fm/adchoices
Beating the Loneliness Epidemic: How ACE's Dr. Cedric Bryant and Dr. Sabrena Jo Help Us Add People to Our Years Live Long Better: Not Old Better and American Council on Exercise Today's show is brought to you by Aura Frames. Aura Frames: the gift that brings your favorite holiday traditions and memories to life every day. If I told you there was a health risk that could quietly raise your chances of early death by roughly 25 to 30 percent… and it wasn't diabetes, blood pressure, or cholesterol… you'd probably lean in. According to the U.S. Surgeon General, loneliness and social isolation increase the risk of premature death by 26% and 29%, and lacking social connection can be as dangerous as smoking up to 15 cigarettes a day. HHS+1 So here's the question for all of us over 60: we count our steps, we count our meds… who's helping us count our people? Welcome to Live Long Better. I'm your host, and today we're tackling the loneliness epidemic head‑on—with movement and community as the prescription Joining us are two leaders from the American Council on Exercise, or ACE. First, our ongoing member of the team, Dr. Sabrena Jo, Senior Director of Science and Education, whose work focuses on how pro‑aging, inclusive fitness and community‑based movement can turn a lonely workout into a welcoming social circle. And we're also joined by Dr. Cedric Bryant, Chief Executive Officer at ACE. Cedric spends his days at the table with organizations like the World Health Organization, the Centers for Disease Control and Prevention, and the National Academies of Science, Engineering and Medicine, championing physical activity as essential public health. ACE Fitness He's authored more than 300 articles and over 40 books, holds a doctorate in physiology from Penn State—where he received the university's Distinguished Alumni Award—and he lives the ACE mission personally with regular exercise, pickleball, golf, and even coaching youth sports. ACE Fitness Cedric often says, "Some activity is better than none, and more is better than some. Every little bit counts." ACE Fitness+1 We'll talk about how that simple idea scales up—from one older adult taking a short walk with a neighbor, to ACE's 40 Forward initiative, a 40th‑anniversary effort to "shape the future of fitness together" by building more inclusive, community‑driven opportunities to move in every kind of neighborhood. ACE Fitness+2ACE Fitness+2 If your contact list has gotten smaller while your pill organizer has gotten bigger, this episode is for you. Because today, we're not just talking about adding years to your life… we're talking about adding people to your years. Stay with us—Dr. Sabrena Jo and Dr. Cedric Bryant are coming up next.
We have another episode in a series of discussions with well-vetted guests from companies that I feel my community would benefit from hearing about Today, I speak with Dr. Stephanie Venn Watson, a veterinary epidemiologist and the co-founder and co-CEO of Serafina Therapeutics. She has worked with the World Health Organization, DARPA, and the US Navy. She has over 70 patents and has authored more than 80 peer-reviewed scientific papers, and her discoveries have featured on NPR, Science Friday, BBC, NBC, and National Geographic. Her groundbreaking discoveries around the health benefits of C15:0 are the topic of a recent book. In our conversation today, we explore longevity molecules and geno-protective molecules, why they matter, and how they work. We cover the basics of rapamycin and glucophage, then dig into the growing body of research on longevity and lifespan, specifically looking at C15:0, what it is, what it does, why it's important, and how it's the first essential fatty acid discovered in decades. We look at its wide-ranging pleiotropic effects on metabolic health, mood, sleep, the brain, gut, and immunity, as well as the signs of low C15:0 levels and the specific labs that can identify a deficiency. We also talk about the benefits of supplementation and improved bioavailability. Since I have been taking C15:0 myself over the last four to five months and noticed improvements in my recovery and sleep, I'm excited to share this informative and helpful conversation, humbly dedicated to the essential saturated fatty acid, C15:0. IN THIS EPISODE, YOU WILL LEARN: • The role C15:0 plays in guiding the aging process and new findings about its benefits for the immune system, brain, and longevity • C15:0's emerging importance as a key player in metabolic balance • What Dr. Venn-Watson's animal studies revealed about the mechanisms of aging in humans • Why women in midlife become more vulnerable to shifts in immune quality and cellular resilience • The ways nutritional deficiencies can appear in blood markers long before symptoms develop • What occurs with red blood cell stability and aging markers when C15:0 levels are too low • Which biomarkers are now being considered early indicators of biological aging • Formulation features of C15:0 that enhance its bioavailability • The multiple bodily systems that can benefit from supplementing with C15:0 Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow) https://www.facebook.com/groups/themidlifepause Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Stephanie Venn-Watson Fatty 15 Discover C15:0 Seraphina Therapeutics On LinkedIn
In April 2023, the World Health Organization released a new report on infertility, which said that around one in sex people worldwide experience infertility at some point in their lives. The WHO's Director-General labelled the phenomenon a major health issue and called for more research in an area that is “still under-studied…and insufficiently funded”. The sheer proportion of affected individuals shows the need to expand access to fertility-related care and ensure that this issue is no longer sidelined in health research and policies. The WHO review was based on 133 fertility studies dating between 1990 and 2021, and showed that no region of the world is spared. What are the causes of such high levels of infertility? What treatments are currently available for people with infertility problems? What could the consequences be? In under 3 minutes, we answer your questions ! To listen to the last episodes, you can click here : Could AI ever be able to offer therapy? How is hygiene poverty affecting over 3 million Brits? What is plasticrust, the latest concerning form of pollution? A podcast written and realised by Joseph Chance. First broadcast: 22/04/2023. Learn more about your ad choices. Visit megaphone.fm/adchoices
The World Health Organization in October published a document promoting a global ID to track your vaccination status from birth. This proposal, which is funded by the Gates Foundation, is another of the WHO's efforts to become the de facto global government. The ID they want to impose on us would give it the power to use vaccination status as a qualifier for travel, education, and government services. We also discuss the US government's bold stance acknowledging that unrestricted immigration, which is coming primarily from Muslim nations, poses an existential threat to the West. This is obvious to anyone who's read world history going back to the 7th century, but most people haven't. We highly recommend the books of Dr. Timothy Furnish and Raymond Ibrahim, and especially Raymond's new book The Two Swords of Christ (https://amzn.to/48IByeV). Sharon's niece, Sarah Sachleben, was recently diagnosed with stage 4 bowel cancer, and the medical bills are piling up. If you are led to help, please go to GilbertHouse.org/hopeforsarah. Follow us! X (formerly Twitter): @pidradio | @sharonkgilbert | @derekgilbert | @gilberthouse_tvTelegram: t.me/gilberthouse | t.me/sharonsroom | t.me/viewfromthebunkerSubstack: gilberthouse.substack.comYouTube: @GilbertHouse | @UnravelingRevelationFacebook.com/pidradio Thank you for making our Build Barn Better project a reality! Our 1,200 square foot pole barn has a new HVAC system, epoxy floor, 100-amp electric service, new windows, insulation, lights, and ceiling fans! If you are so led, you can help out by clicking here: gilberthouse.org/donate. Get our free app! It connects you to this podcast, our weekly Bible studies, and our weekly video programs Unraveling Revelation and A View from the Bunker. The app is available for iOS, Android, Roku, and Apple TV. Links to the app stores are at pidradio.com/app. Video on demand of our best teachings! Stream presentations and teachings based on our research at our new video on demand site: gilberthouse.org/video! Think better, feel better! Our partners at Simply Clean Foods offer freeze-dried, 100% GMO-free food and delicious, vacuum-packed fair trade coffee from Honduras. Find out more at GilbertHouse.org/store/.
This year, for the first time since it was established in 1988, the U.S. did not commemorate World AIDS Day on December 1. That's despite more than 630,000 deaths from HIV-related illnesses in 2024, according to the World Health Organization. This week, we're traveling back in time, to visit a queer church that provided refuge and support to San Francisco's gay community during the height of the AIDS crisis. We're bringing you the first episode of a new podcast called We All Get To Heaven, which draws on sound from 1,200 cassette tapes – recordings of songs, memorials, and sermons from the Metropolitan Community Church. It brings to life voices of loss, and of faith, of people who refused to abandon their spirituality or their queerness, and who built a community that could hold both. Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to Ozempic Weightloss Unlocked, the podcast where we explore how one medicine is reshaping health, lifestyle, and the future of obesity care.Ozempic is the brand name for semaglutide, a medicine that mimics a natural hormone called glucagon like peptide one. It slows digestion, helps the brain feel full, and was first used for diabetes before its powerful weight loss effects were recognized, as explained by experts at Memorial Sloan Kettering Cancer Center.Recently, the World Health Organization issued its first global guideline on these glucagon like peptide one medicines for treating obesity in adults. According to the World Health Organization, long term treatment with these drugs can lead to clinically meaningful weight loss and better metabolic health, but they should almost always be paired with structured changes in diet, physical activity, and regular counseling.The World Health Organization also warns that medication alone will not reverse the obesity crisis. Obesity is now recognized as a chronic disease driven by genetics, environment, poverty, and food systems. That means Ozempic is a tool, not a magic fix.On the policy side, coverage and cost are moving targets. A recent report from Politico described how some state insurance programs in the United States are struggling with the high price of these drugs, even as doctors report patients losing over one hundred pounds and improving conditions like diabetes and sleep apnea. Some states are restricting access to only the most severe cases to control spending.Researchers are also asking how Ozempic affects long term health beyond the scale. Memorial Sloan Kettering Cancer Center reports early evidence that glucagon like peptide one drugs may help reduce the risk of certain cancers linked to obesity, and may help some breast cancer patients lose treatment related weight. At the same time, oncologists stress that more data is needed and that decisions must be individualized.Mental health is another frontier. Think Global Health reports that some studies suggest these medicines might reduce symptoms of anxiety and depression as weight and metabolic health improve, while other research raises concerns about worsened mood or rare suicidal thoughts. Because the early clinical trials often excluded people with serious mental health conditions, experts say we still lack clear answers and call for careful monitoring, realistic expectations, and close contact with a qualified clinician.For older adults, the Association of American Medical Colleges notes that Ozempic and related medicines can be effective but may bring more digestive side effects and a risk of muscle loss. Geriatric specialists recommend a cautious approach, starting with low doses, going slow, and combining the medicine with resistance training and adequate protein to protect strength and function.Across all ages, researchers repeat a common theme. The best outcomes come when Ozempic is combined with lifestyle changes: better nutrition, more movement, improved sleep, and support for mental health. The medicine can quiet constant hunger and cravings, but it works best when listeners use that breathing room to build sustainable habits.In every episode of Ozempic Weightloss Unlocked, we will bring you the latest science, real world experiences, and expert insights so you can better understand how this class of drugs fits into the bigger picture of health.Thank you for tuning in, and remember to subscribe so you never miss an update on Ozempic and the future of weight loss medicine.This has been a quiet please production, for more check out quiet please dot ai. Some great Deals https://amzn.to/49SJ3QsFor more check out http://www.quietplease.aiThis content was created in partnership and with the help of Artificial Intelligence AI
IDPH will now be able to form guidelines using a combination of the CDC's guidance, recommendations from the World Health Organization and other medical and scientific disease prevention experts — and require that immunizations recommended by the state be covered by state-regulated insurance plans.
In today's episode, I'm opening the first chapter of what I believe is the most important series I've ever created — a deep dive into progesterone and why it became the heart of my medical practice. For more than 20 years, I've watched this “simple, humble hormone” transform women's lives in ways most conventional medicine overlooks. What started in two small treatment rooms has grown into a 25,000 sq ft facility, and the core of our success comes down to understanding progesterone's impact on the female brain, stress response, and emotional resilience. In this episode, I break down: Why progesterone is far more than a reproductive hormone How it regulates the female stress response (amygdala, hippocampus, prefrontal cortex) Why anxiety, insomnia, irritability, and emotional overwhelm often map directly to progesterone decline Why so many women feel “unraveled” in their 40s — and why it's not their fault The science behind oral vs. sublingual progesterone (and why I use troches) How conventional medicine often misses the root cause The importance of physicians showing their work, their data, and their citations The lived stories and clinical outcomes that changed how I practice medicine If you've ever felt dismissed, unseen, or told that your anxiety or mood changes are “just stress,” this episode is for you. This is the beginning of a 7-part series where I break down the neurobiology, endocrinology, testing, dosing, delivery methods, breast health, perimenopause, and more. Citations: Brinton, Roberta Diaz, et al. “Neurosteroids and Brain Function.” Steroids, vol. 81, 2014, pp. 61–78. Epperson, C. Neill, et al. “New Insights into Perimenopausal Depression: A Neuroendocrine Vulnerability Framework.” The Lancet Psychiatry, vol. 9, no. 2, 2022, pp. 110–118. Frye, Cheryl A. “Neurosteroids—Endogenous Modulators of GABA_A Receptors.” Pharmacology & Therapeutics, vol. 116, no. 1, 2007, pp. 58–76. Genazzani, Andrea R., et al. “Progesterone, Stress, and the Brain.” Human Reproduction Update, vol. 16, no. 6, 2010, pp. 641–655. Meeker, John D., et al. “Environmental Endocrine Disruptors: Their Effects on Human Reproduction and Development.” Reproductive Toxicology, vol. 25, 2008, pp. 1–7. Mellon, Stanley H. “Neurosteroid Regulation of Central Nervous System Development.” Pharmacology & Therapeutics, vol. 116, 2007, pp. 107–124. Mizrahi, Romy, et al. “The Role of Allopregnanolone in Stress, Mood, and Trauma.” Neurobiology of Stress, vol. 11, 2019, 100198. Paul, Steven M., and Graziano Pinna. “Allopregnanolone: From Molecular Pathways to Therapeutic Applications.” Current Opinion in Neurobiology, vol. 48, 2018, pp. 90–96. Pluchino, Nicoletta, et al. “Progesterone and Allopregnanolone: Effects on the Central Nervous System in the Luteal Phase and in Perimenopause.” Gynecological Endocrinology, vol. 36, no. 6, 2020, pp. 441–445. Rasgon, Natalie L., et al. “Perimenopausal Changes in the Brain and Mood: A Review.” Journal of Clinical Endocrinology and Metabolism, vol. 107, no. 4, 2022, pp. 1120–1134. Reddy, Doodipala Samba. “The Neurosteroid Allopregnanolone and GABA-A Receptor Modulation in Epilepsy and Mood Disorders.” Frontiers in Neuroscience, vol. 12, 2018, 933. Schiller, Crystal E., et al. “The Neuroendocrinology of Perimenopausal Depression.” Trends in Neurosciences, vol. 44, no. 2, 2021, pp. 119–135. Schumacher, Michael, et al. “Neuroprotective Effects of Progesterone and Its Metabolites.” Frontiers in Neuroendocrinology, vol. 33, 2012, pp. 415–439. Selye, Hans. “The General Adaptation Syndrome and the Diseases of Adaptation.” Journal of Clinical Endocrinology, vol. 6, no. 2, 1946, pp. 117–230. Sheng, Jun, and György Buzsáki. “Neuronal Firing and Theta Oscillations in the Amygdala During Fear Conditioning.” Neuron, vol. 53, 2007, pp. 653–667. Smith, Sheryl S. “Progesterone Withdrawal Increases Neuronal Excitability in the Hippocampus: A GABA_A Mechanism.” Journal of Neuroscience, vol. 28, 2008, pp. 10171–10179. Snyder, Jonathan S., et al. “Adult Hippocampal Neurogenesis and Stress Regulation.” Nature Reviews Neuroscience, vol. 12, 2011, pp. 1–9. Stanczyk, Frank Z., and Jerilynn C. Prior. “Progesterone and Progestins: A Review of Pharmacology, PK, and Clinical Use.” Steroids, vol. 82, 2014, pp. 1–8. Tu, Ming-Je, et al. “Oral, Vaginal, and Transdermal Progesterone: PK, Metabolism, and Tissue Distribution.” Drug Metabolism Reviews, vol. 52, no. 2, 2020, pp. 1–28. Wang, Jun, et al. “Stress, Amygdala Plasticity, and the Neuroendocrine Interface.” Nature Neuroscience, vol. 10, 2007, pp. 1093–1100. Weinstock, Marta. “The Hippocampus and Chronic Stress.” Neurochemical Research, vol. 42, 2017, pp. 1–12. World Health Organization. Progesterone and Reproductive Function: Clinical Perspectives. WHO, 2019. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.
Want to listen to this episode ad-free? Visit our Patreon! Welcome true believers to X-Men Horoscopes where each week our host Lodro Rinzler is in conversation with a special guest to discuss the X-Men issue that aligns with a significant month and year from their life and what that issue reveals about their future. With us this week is threepeat guest Cassandra Smith back to talk about the X-Men and trans rights as we explore the Uncanny X-Men Issue (13) that came out the month the World Health Organization ruled that being transgender is not a mental disorder. What does a ragtag team of misfit X-Men hiding in a bar and hunting their old enemies have to say about the future of trans rights? Geez. This one is tough. Also in this episode: Rahne is in her sexy era Cyclops tea bags X-Men villains Putting underwear on over your clothes Havok is bored because all of his friends are dead Lodro is upset by Cyclops' sartorial choices Don't shave the hair off my Barbie! None of the X-Men in this era have hobbies Cyclops sleeps in a single bed What does this Dark Beast-laden issue mean for the future of marginalized communities in these dark times? Tune in to find out! Cassie Smith is a truly creative person, having trained as an actress, most notably at the celebrated National Youth Theatre of London, who has also successfully dabbled in modeling and voiceover work before settling into her skills as a writer, with her first article published in 2021 detailing her perspective as a transgender girl in the modern world. She is an activist at heart, a champion for LGBTQ rights and the fight against racism, lending her voice as an educational public speaker, shedding light on the history and facts surrounding the culture war on trans people. As an avid comic book reader from an early age, Cassie is considered a “go-to” girl when it comes to comics. This lends perfectly to her super fun content coverage as a bubbly Tiktoker and across social media, diving into nerd culture, comic book characters, history and lore! You can find her on Instagram, TikTok and on her monthly publication at Substack. More of Lodro Rinzler's work can be found here and here and you can follow the podcast on Instagram at xmenpanelsdaily where we post X-Men comic panels...daily. Have a question or comment for a future episode? Reach out at xmenhoroscopes.com Want to listen to these episodes early/ad-free and get your own X-Men Horoscope read/an awesome t-shirt? Check out our brand-new patreon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Practice ownership comes with a unique paradox: the autonomy you fought for also means carrying the full weight of clinical work, business management, and leadership. In this episode, Tracy breaks down the World Health Organization's three-phase burnout framework and reveals why nearly half of all physicians are experiencing burnout symptoms—and what makes practice owner burnout distinctly different and dangerous. Click here for full show notes Is your practice growth-ready? See Where Your Practice Stands: Take our Practice Growth Readiness Assessment Episode Highlights The WHO's three phases of burnout: exhaustion, cynicism, and reduced professional efficacy—and why recognizing which phase you're in determines what help you need Why American culture makes Phase 1 exhaustion nearly impossible to recognize (hint: we've been conditioned to see depletion as a badge of honor) The shocking global statistics: from 43% burnout rates in the US to 66% emotional exhaustion among Portuguese physicians Why practice owner burnout can't be solved with employed physician solutions—you can't "delegate up" when you ARE the up Real examples of what each phase looks like: from sitting in your driveway without energy to enter your home, to thinking cynical thoughts that horrify you The $4.6 billion annual cost of physician burnout to the US healthcare system—and the incalculable personal cost to you, your practice, and your family Why autonomy alone isn't enough: the protection it provides versus the isolation and weight it creates Memorable Quotes "Burnout is not a personal failing. It's a predictable occupational phenomenon with identifiable phases." "Phase one exhaustion is your prevention opportunity. This is where you still have an easy exit ramp. If you catch yourself and actually address it—not by doubling down, but by making strategic changes—prevention strategies actually work." "You can't think your way out of cynicism using the same thinking that got you there." "Your practice will survive a few weeks without you, but you might not survive continuing to push through phase three." "When you're the owner, you can't just leave. Your practice is your livelihood, your investment, and your legacy." "You are not broken. You are not weak. You are responding predictably to chronic stress that hasn't been successfully managed." Closing Understanding burnout isn't about labeling yourself—it's about getting clear on what level of support you actually need. Whether you're in the prevention zone, need intervention, or are facing a crisis, there's a path forward. Join us next episode as we dive into the strategic prevention approaches that work specifically for independent practice owners. Tracy's Bio: Tracy Cherpeski, MBA, MA, CPSC (she/her/hers) is the Founder of Tracy Cherpeski International and Thriving Practice Community. As a Business Consultant and Executive Coach, Tracy helps healthcare practice owners scale their businesses without sacrificing wellbeing. Through strategic planning, leadership development, and mindset mastery, she empowers clients to reclaim their time and reach their potential. Based in Chapel Hill, NC, Tracy serves clients worldwide and is the Executive Producer and Host of the Thriving Practice podcast. Her guiding philosophy: Survival is not enough; life is meant to be celebrated. Connect With Us: Be a Guest on the Show Thriving Practice Community Schedule Strategy Session with Tracy Tracy's LinkedIn Business LinkedIn Page
After months of fighting, the Kremlin says Russian forces have seized the frontline city of Pokrovsk in eastern Ukraine. It links several other key cities in the Donetsk region. Last month, Ukraine sent reinforcements to try to fend off the Russian attack. Kyiv has not acknowledged the loss of the city. Also: the White House defends Defence Secretary Pete Hegseth over US military action off the coast of Venezuela; the presidential election result in Honduras is too close to call; the World Health Organization calls for weight loss jabs to be more widely available; what Australian teenagers make of an up-coming social media ban; the eighty-five-kilometre long traffic jam in Siberia; and an interview with the Taiwanese director who shot a critically-acclaimed film on iPhones.The Global News Podcast brings you the breaking news you need to hear, as it happens. Listen for the latest headlines and current affairs from around the world. Politics, economics, climate, business, technology, health – we cover it all with expert analysis and insight. Get the news that matters, delivered twice a day on weekdays and daily at weekends, plus special bonus episodes reacting to urgent breaking stories. Follow or subscribe now and never miss a moment. Get in touch: globalpodcast@bbc.co.uk
Dr. Jeffrey Kopin, Chief Medical Officer for Northwestern Medicine Catherine Gratz Griffin Lake Forest Hospital, joins John Williams to talk about what you can take to combat the common cold, the World Health Organization issuing the first-ever guidelines for use of GLP-1 weight loss medications, and what you can do to protect yourself from Norovirus.
Dr. Jeffrey Kopin, Chief Medical Officer for Northwestern Medicine Catherine Gratz Griffin Lake Forest Hospital, joins John Williams to talk about what you can take to combat the common cold, the World Health Organization issuing the first-ever guidelines for use of GLP-1 weight loss medications, and what you can do to protect yourself from Norovirus.
Weight loss drugs have once again dominated health headlines.The World Health Organization has endorsed Ozempic-type drugs for long-term obesity treatment, while Australia's TGA has issues new safety alerts - so what's going on here? Plus, we dive into the contentious Oxford Word of the Year, and why it was some people raging... literally. And in headlines today, A suppression order has been lifted allowing reporting on the dark history of Greg Lynn; Disgraced former political staffer Bruce Lehrmann will learn today whether a an appeal to overturn a court ruling he probably raped colleague Brittany Higgins is successful; Palestinian militant group Hamas says it is handing over the remains of one of the two last hostage bodies still in the Gaza Strip; The Prada Group has officially purchased Milan fashion rival Versace in a 1.25 billion euro ($A2.21 billion) deal; Miley Cyrus is engaged to musician Maxx Morando THE END BITS Support independent women's media Check out The Quicky Instagram here GET IN TOUCHShare your story, feedback, or dilemma! Send us a voice note or email us at thequicky@mamamia.com.au CREDITS Hosts: Taylah Strano & Claire Murphy Guests: Dr Terri-Lynne South, Chair of RACGP Specific Interests Obesity ManagementMyf Warhurst, cultural commentator & host of The Moment podcast Audio Producer: Lu Hill Become a Mamamia subscriber: https://www.mamamia.com.au/subscribeSee omnystudio.com/listener for privacy information.
Dr. Jeffrey Kopin, Chief Medical Officer for Northwestern Medicine Catherine Gratz Griffin Lake Forest Hospital, joins John Williams to talk about what you can take to combat the common cold, the World Health Organization issuing the first-ever guidelines for use of GLP-1 weight loss medications, and what you can do to protect yourself from Norovirus.
Walking is something we all do every day, but did you know it has numerous health benefits? It's not just a simple way to get from point A to point B; walking can improve cardiovascular health, boost your mood, and even enhance your overall well-being. According to specialists, it can also help you lose weight under certain conditions. By incorporating regular, brisk walks into your routine, you can take advantage of these benefits and work towards your weight loss goals. First, you need to walk enough. The World Health Organization (WHO) recommends at least 10,000 steps a day to stay fit and maintain a stable weight. But if your goal is to lose weight, you'll need to walk more and at a higher intensity. To really shed those pounds, aim to walk at least three times a week for an hour or more at a brisk pace (between 6 and 8 km/h) and maintain a heart rate between 135 and 160 beats per minute. So, what are those conditions? Is that enough to lose weight? Is one type of walking more effective than another? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: What is the 10-10-10 method for dealing with everyday worries? Why has astrology come back into fashion? What are the most addictive foods? A podcast written and realised by Amber Minogue. First Broadcast : 4/9/2024 Learn more about your ad choices. Visit megaphone.fm/adchoices
The World Health Organization is officially recommending GLP-1 drugs for obesity, reshaping the global weight-loss conversation. Plus, we break down the Pizza Economy — how rising prices are influencing what people order, which toppings are getting cut, and why your favorite slice might be pricier next month. Smart takes, sharp laughs, and all the news you didn’t realize you needed.See omnystudio.com/listener for privacy information.
The head of the Office for Budget Responsibility, Richard Hughes, has resigned after his organisation released details of the budget before the Chancellor had delivered her speech. Also: The Prime Minister has denied that the Rachel Reeves misled people about the state of the public finances. And the World Health Organisation calls for fairer access to weight loss jabs.
Monday is World AIDS Day, but the United States government is sitting out the commemoration this year. The World Health Organization created the day in the 1980s to remember those lost to the disease and rally support for prevention and treatment. This is the first year since 1993 that the President of the United States has not signed a proclamation to recognize the day. The Trump Administration also told federal employees not to use government funds or social media for World AIDS Day, according to the New York Times. Matt Toburen leads the Aliveness Project, which supports people living with HIV in the Twin Cities. He joined Minnesota Now host Nina Moini to talk about how his organization is still raising awareness.
Algoma Steel is laying off about a thousand workers — roughly a third of its workforce. The company is pointing to the effects of U.S. tariffs. But it also had government help: half a billion dollars that was supposed to keep workers on the job.And: A fire has been burning through a Toronto highrise complex for more than four days now. But no one can see it. It's smouldering between the concrete walls of two connected buildings, posing an especially complex challenge to firefighters.Also: For the first time, the World Health Organization is recommending GLP-1 drugs like Ozempic as a treatment for obesity. It's a condition that affects millions, and costs billions. But how much medications can help will depend in part on who can get access.Plus: Officials in Manitoba begin another painstaking search in another landfill for the remains of two Indigenous women, the Trump administration faces accusations of war crimes in connection to strikes on an alleged Caribbean drug boat, and more.
CBS Reporter Brad Gibson explains the new rules for doctors set out by the World Health Organization as GLP-1 drugs are becoming easier to obtain. With Megan Lynch.
작성자: 최정윤, Tannith KrielWhat drove Korea's school meal workers out of the kitchen?기사 요약: 학교 급식실 노동자들이 파업에 나서 학생들이 대체식을 먹는 가운데, 노동자들은 낮은 임금과 강도 높은 업무가 자신들의 건강까지 위협하고 있다고 주장했다.[1] School cooks and other nonregular school staff began a nationwide walkout last week, calling for improved wages, pay during school breaks and better welfare. But the workers say these demands, while important, only skim the surface of what pushed thousands to walk out of Korea's schools.walkout: 파업 (=strike)A walkout is a spontaneous or planned protest where workers leave their jobs together, while a strike is a more formal, organized work stoppage, often with a specific union vote and no set end dateskim: 훑어보다, 표면을 스치다[2] The school staff strike has been sparked by a deeper crisis, they say — one shaped by toxic working environments that treat the workers responsible for feeding Korea's children as second-class citizens.treat: 어떤 태도로 대하다, 대접하다 / 선물, 간식[3] The workers say they have suffered years of breathing carcinogenic fumes, fainting in overheated kitchens, returning to work with lingering injuries and watching coworkers fall ill, sometimes fatally.carcinogenic: 발암성의, 암을 유발하는faint: 기절하다lingering: 오래 끄는, 사라지지 않는[4] They cite the case of a Seoul school cafeteria worker in her 50s, who learned she had lung cancer in 2023 after a CT scan. Doctors suggested it was caused by cooking fumes generated during frying and high-heat food preparation. The World Health Organization classifies these cooking emissions as probably carcinogenic.cite: 예를 들다기사 원문: https://www.koreaherald.com/article/10622632
In this episode of Crazy Wisdom, I, Stewart Alsop, sit down with Argentine artist Mathilda Martin to explore the intimate connection between creativity, flow, and authenticity—from how swimming mirrors painting, to why art can heal, and what makes human-made art irreplaceable in the age of AI. We also touch on Argentina's vibrant art scene, the shift in the art world after COVID, and the fine line between commercial and soulful creation. You can find Mathilda's work on Instagram at @arte_mathilda.Check out this GPT we trained on the conversationTimestamps00:00 – Mathilda Martin joins Stewart Alsop to talk about art, creativity, and her upcoming exhibitions in Miami and Uruguay.05:00 – She shares how swimming connects to painting, describing water as calm, presence, and a source of flow and meditation.10:00 – They discuss art as therapy, childhood creativity, and overcoming fear by simply starting to create.15:00 – Mathilda reflects on her love for Van Gogh and feeling as the essence of authentic art, contrasting it with the coldness of AI.20:00 – The conversation turns to the value of human-made art and whether galleries can tell the difference between AI and real artists.25:00 – They explore Argentine authenticity, “chantas,” and what makes Argentina both chaotic and deeply real.30:00 – Mathilda talks about solidarity, community, and daily life in Buenos Aires amid political and economic instability.35:00 – She highlights Argentine muralists and how collaboration and scale transform artistic expression.40:00 – The pair discuss the commercialization of art, the “factory artist,” and staying true to feeling over fame.45:00 – Mathilda explains how COVID reshaped the art world, empowering independent artists to exhibit without galleries.50:00 – They end with art markets in Argentina vs. the U.S., her gallery in New York, and upcoming shows at Spectrum Miami and Punta del Este.Key InsightsArt and Water Share the Same Flow: Mathilda Martin reveals how swimming and painting both bring her into a meditative state she calls “the pause.” In the water, she feels the same stillness she experiences while painting — a total immersion in the present moment where the outside world disappears.Art Is a Form of Healing: Mathilda emphasizes that art is not just expression but medicine. She references the World Health Organization's recognition that creativity benefits mental and physical health, describing painting as a space of emotional regulation and clarity.Human-Made Art Has Soul, AI Doesn't: One of the episode's most thought-provoking moments comes when Mathilda contrasts the warmth of human-made art with the cold precision of AI. She believes that while AI can replicate technique, it can't replicate feeling — and that collectors will always value art infused with human emotion.Authenticity Defines Argentine Culture: Mathilda paints a vivid picture of Argentina as a land of contradictions — full of chaos, charm, and honesty. Argentines, she says, are “authentic, sometimes too direct,” a quality that shapes both their relationships and their art.COVID-19 Changed the Art World Forever: The pandemic disrupted the old gallery system and gave artists freedom to organize their own exhibitions. For Mathilda, this shift created independence, even if it also demanded new entrepreneurial skills.Commercial Success vs. Soulful Creation: Mathilda critiques “factory artists” who mass-produce work for fame or profit, contrasting them with artists who create from genuine emotion. The real challenge, she says, is maintaining authenticity in a system that rewards volume over vulnerability.Art as Connection and Presence: Beyond skill or aesthetics, Mathilda believes true art is about human connection — between artist, viewer, and the moment of creation itself. Whether painting, swimming, or teaching workshops, she views art as an ongoing conversation with life's deeper flow.
Headaches are one of the most common neurological conditions in the world. They're also one of the most debilitating, mysterious, and misunderstood.According to the World Health Organization, 3 billion people worldwide suffer from headache disorders. And one in six Americans suffers from headaches that are so severe they limit their ability to work, sleep, or otherwise function.We discuss headaches as a part of our series “In Good Health,” where we talk about the bodily issues that most affect us. What do we know about headaches and who they affect? What works when it comes to treating headaches?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
This week on The Broski Report, Fearless Leader Brittany Broski addresses some recent rumors, shares her Thanksgiving invite list, and researches gelatinous food. Watch The Broski Report AD FREE: https://patreon.com/broskireport The OFFICIAL Songs of The Week Playlist: https://open.spotify.com/playlist/3ULrcEqO2JafGZPeonyuje?si=061c5c0dd4664f01
In a moment marked by rising geopolitical instability, accelerating climate change, recurring pandemics, and deep economic uncertainty, nursing stands at a critical crossroads. The global nursing workforce is already under severe strain, and the World Health Organization projects a shortfall of approximately 4.5 million nurses by 2030. Yet, even as health needs become more complex, health funding is being reduced in many parts of the world while defense spending rises, deepening the resource constraints facing nurses and other frontline health workers. So, what does it truly mean to invest in nursing? For the International Council of Nurses, it means speaking value to power, making the case consistently and convincingly, that nurses are essential to the stability and well-being of individuals, families, communities, and entire nations. It means pushing forward despite workforce shortages, policy barriers, violence, and chronic underfunding. It means dismantling myths and hierarchies and advancing rigorous research to demonstrate the economic and societal return on educating, compensating, and recognizing nurses as the indispensable professionals they are. In this episode, Oriana Beaudet, VP of Innovation at the American Nurses Association, Credentialing Center, and Foundation, connects with Howard Catton, the Chief Executive Officer of the International Council of Nurses, who is driving global efforts to support nurses at the ICN. Together, they explore the inventive strategies, advocacy work, and bold solutions shaping the future of nursing. And talk about what it means to meet global challenges with clarity, commitment, and heart.
How can you write science-based fiction without info-dumping your research? How can you use AI tools in a creative way, while still focusing on a human-first approach? Why is adapting to the fast pace of change so difficult and how can we make the most of this time? Jamie Metzl talks about Superconvergence and more. In the intro, How to avoid author scams [Written Word Media]; Spotify vs Audible audiobook strategy [The New Publishing Standard]; Thoughts on Author Nation and why constraints are important in your author life [Self-Publishing with ALLi]; Alchemical History And Beautiful Architecture: Prague with Lisa M Lilly on my Books and Travel Podcast. Today's show is sponsored by Draft2Digital, self-publishing with support, where you can get free formatting, free distribution to multiple stores, and a host of other benefits. Just go to www.draft2digital.com to get started. This show is also supported by my Patrons. Join my Community at Patreon.com/thecreativepenn Jamie Metzl is a technology futurist, professional speaker, entrepreneur, and the author of sci-fi thrillers and futurist nonfiction books, including the revised and updated edition of Superconvergence: How the Genetics, Biotech, and AI Revolutions Will Transform Our Lives, Work, and World. You can listen above or on your favorite podcast app or read the notes and links below. Here are the highlights and the full transcript is below. Show Notes How personal history shaped Jamie's fiction writing Writing science-based fiction without info-dumping The super convergence of three revolutions (genetics, biotech, AI) and why we need to understand them holistically Using fiction to explore the human side of genetic engineering, life extension, and robotics Collaborating with GPT-5 as a named co-author How to be a first-rate human rather than a second-rate machine You can find Jamie at JamieMetzl.com. Transcript of interview with Jamie Metzl Jo: Jamie Metzl is a technology futurist, professional speaker, entrepreneur, and the author of sci-fi thrillers and futurist nonfiction books, including the revised and updated edition of Superconvergence: How the Genetics, Biotech, and AI Revolutions Will Transform Our Lives, Work, and World. So welcome, Jamie. Jamie: Thank you so much, Jo. Very happy to be here with you. Jo: There is so much we could talk about, but let's start with you telling us a bit more about you and how you got into writing. From History PhD to First Novel Jamie: Well, I think like a lot of writers, I didn't know I was a writer. I was just a kid who loved writing. Actually, just last week I was going through a bunch of boxes from my parents' house and I found my autobiography, which I wrote when I was nine years old. So I've been writing my whole life and loving it. It was always something that was very important to me. When I finished my DPhil, my PhD at Oxford, and my dissertation came out, it just got scooped up by Macmillan in like two minutes. And I thought, “God, that was easy.” That got me started thinking about writing books. I wanted to write a novel based on the same historical period – my PhD was in Southeast Asian history – and I wanted to write a historical novel set in the same period as my dissertation, because I felt like the dissertation had missed the human element of the story I was telling, which was related to the Cambodian genocide and its aftermath. So I wrote what became my first novel, and I thought, “Wow, now I'm a writer.” I thought, “All right, I've already published one book. I'm gonna get this other book out into the world.” And then I ran into the brick wall of: it's really hard to be a writer. It's almost easier to write something than to get it published. I had to learn a ton, and it took nine years from when I started writing that first novel, The Depths of the Sea, to when it finally came out. But it was such a positive experience, especially to have something so personal to me as that story. I'd lived in Cambodia for two years, I'd worked on the Thai-Cambodian border, and I'm the child of a Holocaust survivor. So there was a whole lot that was very emotional for me. That set a pattern for the rest of my life as a writer, at least where, in my nonfiction books, I'm thinking about whatever the issues are that are most important to me. Whether it was that historical book, which was my first book, or Hacking Darwin on the future of human genetic engineering, which was my last book, or Superconvergence, which, as you mentioned in the intro, is my current book. But in every one of those stories, the human element is so deep and so profound. You can get at some of that in nonfiction, but I've also loved exploring those issues in deeper ways in my fiction. So in my more recent novels, Genesis Code and Eternal Sonata, I've looked at the human side of the story of genetic engineering and human life extension. And now my agent has just submitted my new novel, Virtuoso, about the intersection of AI, robotics, and classical music. With all of this, who knows what's the real difference between fiction and nonfiction? We're all humans trying to figure things out on many different levels. Shifting from History to Future Tech Jo: I knew that you were a polymath, someone who's interested in so many things, but the music angle with robotics and AI is fascinating. I do just want to ask you, because I was also at Oxford – what college were you at? Jamie: I was in St. Antony's. Jo: I was at Mansfield, so we were in that slightly smaller, less famous college group, if people don't know. Jamie: You know, but we're small but proud. Jo: Exactly. That's fantastic. You mentioned that you were on the historical side of things at the beginning and now you've moved into technology and also science, because this book Superconvergence has a lot of science. So how did you go from history and the past into science and the future? Biology and Seeing the Future Coming Jamie: It's a great question. I'll start at the end and then back up. A few years ago I was speaking at Lawrence Livermore National Laboratory, which is one of the big scientific labs here in the United States. I was a guest of the director and I was speaking to their 300 top scientists. I said to them, “I'm here to speak with you about the future of biology at the invitation of your director, and I'm really excited. But if you hear something wrong, please raise your hand and let me know, because I'm entirely self-taught. The last biology course I took was in 11th grade of high school in Kansas City.” Of course I wouldn't say that if I didn't have a lot of confidence in my process. But in many ways I'm self-taught in the sciences. As you know, Jo, and as all of your listeners know, the foundation of everything is curiosity and then a disciplined process for learning. Even our greatest super-specialists in the world now – whatever their background – the world is changing so fast that if anyone says, “Oh, I have a PhD in physics/chemistry/biology from 30 years ago,” the exact topic they learned 30 years ago is less significant than their process for continuous learning. More specifically, in the 1990s I was working on the National Security Council for President Clinton, which is the president's foreign policy staff. My then boss and now close friend, Richard Clarke – who became famous as the guy who had tragically predicted 9/11 – used to say that the key to efficacy in Washington and in life is to try to solve problems that other people can't see. For me, almost 30 years ago, I felt to my bones that this intersection of what we now call AI and the nascent genetics revolution and the nascent biotechnology revolution was going to have profound implications for humanity. So I just started obsessively educating myself. When I was ready, I started writing obscure national security articles. Those got a decent amount of attention, so I was invited to testify before the United States Congress. I was speaking out a lot, saying, “Hey, this is a really important story. A lot of people are missing it. Here are the things we should be thinking about for the future.” I wasn't getting the kind of traction that I wanted. I mentioned before that my first book had been this dry Oxford PhD dissertation, and that had led to my first novel. So I thought, why don't I try the same approach again – writing novels to tell this story about the genetics, biotech, and what later became known popularly as the AI revolution? That led to my two near-term sci-fi novels, Genesis Code and Eternal Sonata. On my book tours for those novels, when I explained the underlying science to people in my way, as someone who taught myself, I could see in their eyes that they were recognizing not just that something big was happening, but that they could understand it and feel like they were part of that story. That's what led me to write Hacking Darwin, as I mentioned. That book really unlocked a lot of things. I had essentially predicted the CRISPR babies that were born in China before it happened – down to the specific gene I thought would be targeted, which in fact was the case. After that book was published, Dr. Tedros, the Director-General of the World Health Organization, invited me to join the WHO Expert Advisory Committee on Human Genome Editing, which I did. It was a really great experience and got me thinking a lot about the upside of this revolution and the downside. The Birth of Superconvergence Jamie: I get a lot of wonderful invitations to speak, and I have two basic rules for speaking: Never use notes. Never ever. Never stand behind a podium. Never ever. Because of that, when I speak, my talks tend to migrate. I'd be speaking with people about the genetics revolution as it applied to humans, and I'd say, “Well, this is just a little piece of a much bigger story.” The bigger story is that after nearly four billion years of life on Earth, our one species has the increasing ability to engineer novel intelligence and re-engineer life. The big question for us, and frankly for the world, is whether we're going to be able to use that almost godlike superpower wisely. As that idea got bigger and bigger, it became this inevitable force. You write so many books, Jo, that I think it's second nature for you. Every time I finish a book, I think, “Wow, that was really hard. I'm never doing that again.” And then the books creep up on you. They call to you. At some point you say, “All right, now I'm going to do it.” So that was my current book, Superconvergence. Like everything, every journey you take a step, and that step inspires another step and another. That's why writing and living creatively is such a wonderfully exciting thing – there's always more to learn and always great opportunities to push ourselves in new ways. Balancing Deep Research with Good Storytelling Jo: Yeah, absolutely. I love that you've followed your curiosity and then done this disciplined process for learning. I completely understand that. But one of the big issues with people like us who love the research – and having read your Superconvergence, I know how deeply you go into this and how deeply you care that it's correct – is that with fiction, one of the big problems with too much research is the danger of brain-dumping. Readers go to fiction for escapism. They want the interesting side of it, but they want a story first. What are your tips for authors who might feel like, “Where's the line between putting in my research so that it's interesting for readers, but not going too far and turning it into a textbook?” How do you find that balance? Jamie: It's such a great question. I live in New York now, but I used to live in Washington when I was working for the U.S. government, and there were a number of people I served with who later wrote novels. Some of those novels felt like policy memos with a few sex scenes – and that's not what to do. To write something that's informed by science or really by anything, everything needs to be subservient to the story and the characters. The question is: what is the essential piece of information that can convey something that's both important to your story and your character development, and is also an accurate representation of the world as you want it to be? I certainly write novels that are set in the future – although some of them were a future that's now already happened because I wrote them a long time ago. You can make stuff up, but as an author you have to decide what your connection to existing science and existing technology and the existing world is going to be. I come at it from two angles. One: I read a huge number of scientific papers and think, “What does this mean for now, and if you extrapolate into the future, where might that go?” Two: I think about how to condense things. We've all read books where you're humming along because people read fiction for story and emotional connection, and then you hit a bit like: “I sat down in front of the president, and the president said, ‘Tell me what I need to know about the nuclear threat.'” And then it's like: insert memo. That's a deal-killer. It's like all things – how do you have a meaningful relationship with another person? It's not by just telling them your story. Even when you're telling them something about you, you need to be imagining yourself sitting in their shoes, hearing you. These are very different disciplines, fiction and nonfiction. But for the speculative nonfiction I write – “here's where things are now, and here's where the world is heading” – there's a lot of imagination that goes into that too. It feels in many ways like we're living in a sci-fi world because the rate of technological change has been accelerating continuously, certainly for the last 12,000 years since the dawn of agriculture. It's a balance. For me, I feel like I'm a better fiction writer because I write nonfiction, and I'm a better nonfiction writer because I write fiction. When I'm writing nonfiction, I don't want it to be boring either – I want people to feel like there's a story and characters and that they can feel themselves inside that story. Jo: Yeah, definitely. I think having some distance helps as well. If you're really deep into your topics, as you are, you have to leave that manuscript a little bit so you can go back with the eyes of the reader as opposed to your eyes as the expert. Then you can get their experience, which is great. Looking Beyond Author-Focused AI Fears Jo: I want to come to your technical knowledge, because AI is a big thing in the author and creative community, like everywhere else. One of the issues is that creators are focusing on just this tiny part of the impact of AI, and there's a much bigger picture. For example, in 2024, Demis Hassabis from Google DeepMind and his collaborative partner John Jumper won the Nobel Prize for Chemistry with AlphaFold. It feels to me like there's this massive world of what's happening with AI in health, climate, and other areas, and yet we are so focused on a lot of the negative stuff. Maybe you could give us a couple of things about what there is to be excited and optimistic about in terms of AI-powered science? Jamie: Sure. I'm so excited about all of the new opportunities that AI creates. But I also think there's a reason why evolution has preserved this very human feeling of anxiety: because there are real dangers. Anybody who's Pollyanna-ish and says, “Oh, the AI story is inevitably positive,” I'd be distrustful. And anyone who says, “We're absolutely doomed, this is the end of humanity,” I'd also be distrustful. So let me tell you the positives and the negatives, and maybe some thoughts about how we navigate toward the former and away from the latter. AI as the New Electricity Jamie: When people think of AI right now, they're thinking very narrowly about these AI tools and ChatGPT. But we don't think of electricity that way. Nobody says, “I know electricity – electricity is what happens at the power station.” We've internalised the idea that electricity is woven into not just our communication systems or our houses, but into our clothes, our glasses – it's woven into everything and has super-empowered almost everything in our modern lives. That's what AI is. In Superconvergence, the majority of the book is about positive opportunities: In healthcare, moving from generalised healthcare based on population averages to personalised or precision healthcare based on a molecular understanding of each person's individual biology. As we build these massive datasets like the UK Biobank, we can take a next jump toward predictive and preventive healthcare, where we're able to address health issues far earlier in the process, when interventions can be far more benign. I'm really excited about that, not to mention the incredible new kinds of treatments – gene therapies, or pharmaceuticals based on genetics and systems-biology analyses of patients. Then there's agriculture. Over the last hundred years, because of the technologies of the Green Revolution and synthetic fertilisers, we've had an incredible increase in agricultural productivity. That's what's allowed us to quadruple the global population. But if we just continue agriculture as it is, as we get towards ten billion wealthier, more empowered people wanting to eat like we eat, we're going to have to wipe out all the wild spaces on Earth to feed them. These technologies help provide different paths toward increasing agricultural productivity with fewer inputs of land, water, fertiliser, insecticides, and pesticides. That's really positive. I could go on and on about these positives – and I do – but there are very real negatives. I was a member of the WHO Expert Advisory Committee on Human Genome Editing after the first CRISPR babies were very unethically created in China. I'm extremely aware that these same capabilities have potentially incredible upsides and very real downsides. That's the same as every technology in the past, but this is happening so quickly that it's triggering a lot of anxieties. Governance, Responsibility, and Why Everyone Has a Role Jamie: The question now is: how do we optimise the benefits and minimise the harms? The short, unsexy word for that is governance. Governance is not just what governments do; it's what all of us do. That's why I try to write books, both fiction and nonfiction, to bring people into this story. If people “other” this story – if they say, “There's a technology revolution, it has nothing to do with me, I'm going to keep my head down” – I think that's dangerous. The way we're going to handle this as responsibly as possible is if everybody says, “I have some role. Maybe it's small, maybe it's big. The first step is I need to educate myself. Then I need to have conversations with people around me. I need to express my desires, wishes, and thoughts – with political leaders, organisations I'm part of, businesses.” That has to happen at every level. You're in the UK – you know the anti-slavery movement started with a handful of people in Cambridge and grew into a global movement. I really believe in the power of ideas, but ideas don't spread on their own. These are very human networks, and that's why writing, speaking, communicating – probably for every single person listening to this podcast – is so important. Jo: Mm, yeah. Fiction Like AI 2041 and Thinking Through the Issues Jo: Have you read AI 2041 by Kai-Fu Lee and Chen Qiufan? Jamie: No. I heard a bunch of their interviews when the book came out, but I haven't read it. Jo: I think that's another good one because it's fiction – a whole load of short stories. It came out a few years ago now, but the issues they cover in the stories, about different people in different countries – I remember one about deepfakes – make you think more about the topics and help you figure out where you stand. I think that's the issue right now: it's so complex, there are so many things. I'm generally positive about AI, but of course I don't want autonomous drone weapons, you know? The Messy Reality of “Bad” Technologies Jamie: Can I ask you about that? Because this is why it's so complicated. Like you, I think nobody wants autonomous killer drones anywhere in the world. But if you right now were the defence minister of Ukraine, and your children are being kidnapped, your country is being destroyed, you're fighting for your survival, you're getting attacked every night – and you're getting attacked by the Russians, who are investing more and more in autonomous killer robots – you kind of have two choices. You can say, “I'm going to surrender,” or, “I'm going to use what technology I have available to defend myself, and hopefully fight to either victory or some kind of stand-off.” That's what our societies did with nuclear weapons. Maybe not every American recognises that Churchill gave Britain's nuclear secrets to America as a way of greasing the wheels of the Anglo-American alliance during the Second World War – but that was our programme: we couldn't afford to lose that war, and we couldn't afford to let the Nazis get nuclear weapons before we did. So there's the abstract feeling of, “I'm against all war in the abstract. I'm against autonomous killer robots in the abstract.” But if I were the defence minister of Ukraine, I would say, “What will it take for us to build the weapons we can use to defend ourselves?” That's why all this stuff gets so complicated. And frankly, it's why the relationship between fiction and nonfiction is so important. If every novel had a situation where every character said, “Oh, I know exactly the right answer,” and then they just did the right answer and it was obviously right, it wouldn't make for great fiction. We're dealing with really complex humans. We have conflicting impulses. We're not perfect. Maybe there are no perfect answers – but how do we strive toward better rather than worse? That's the question. Jo: Absolutely. I don't want to get too political on things. How AI Is Changing the Writing Life Jo: Let's come back to authors. In terms of the creative process, the writing process, the research process, and the business of being an author – what are some of the ways that you already use AI tools, and some of the ways, given your futurist brain, that you think things are going to change for us? Jamie: Great question. I'll start with a little middle piece. I found you, Jo, through GPT-5. I asked ChatGPT, “I'm coming out with this book and I want to connect with podcasters who are a little different from the ones I've done in the past. I've been a guest on Joe Rogan twice and some of the bigger podcasts. Make me a list of really interesting people I can have great conversations with.” That's how I found you. So this is one reward of that process. Let me say that in the last year I've worked on three books, and I'll explain how my relationship with AI has changed over those books. Cleaning Up Citations (and Getting Burned) Jamie: First is the highly revised paperback edition of Superconvergence. When the hardback came out, I had – I don't normally work with research assistants because I like to dig into everything myself – but the one thing I do use a research assistant for is that I can't be bothered, when I'm writing something, to do the full Chicago-style footnote if I'm already referencing an academic paper. So I'd just put the URL as the footnote and then hire a research assistant and say, “Go to this URL and change it into a Chicago-style citation. That's it.” Unfortunately, my research assistant on the hardback used early-days ChatGPT for that work. He did the whole thing, came back, everything looked perfect. I said, “Wow, amazing job.” It was only later, as I was going through them, that I realised something like 50% of them were invented footnotes. It was very painful to go back and fix, and it took ten times more time. With the paperback edition, I didn't use AI that much, but I did say things like, “Here's all the information – generate a Chicago-style citation.” That was better. I noticed there were a few things where I stopped using the thesaurus function on Microsoft Word because I'd just put the whole paragraph into the AI and say, “Give me ten other options for this one word,” and it would be like a contextual thesaurus. That was pretty good. Talking to a Robot Pianist Character Jamie: Then, for my new novel Virtuoso, I was writing a character who is a futurist robot that plays the piano very beautifully – not just humanly, but almost finding new things in the music we've written and composing music that resonates with us. I described the actions of that robot in the novel, but I didn't describe the inner workings of the robot's mind. In thinking about that character, I realised I was the first science-fiction writer in history who could interrogate a machine about what it was “thinking” in a particular context. I had the most beautiful conversations with ChatGPT, where I would give scenarios and ask, “What are you thinking? What are you feeling in this context?” It was all background for that character, but it was truly profound. Co-Authoring The AI Ten Commandments with GPT-5 Jamie: Third, I have another book coming out in May in the United States. I gave a talk this summer at the Chautauqua Institution in upstate New York about AI and spirituality. I talked about the history of our human relationship with our technology, about how all our religious and spiritual traditions have deep technological underpinnings – certainly our Abrahamic religions are deeply connected to farming, and Protestantism to the printing press. Then I had a section about the role of AI in generating moral codes that would resonate with humans. Everybody went nuts for this talk, and I thought, “I think I'm going to write a book.” I decided to write it differently, with GPT-5 as my named co-author. The first thing I did was outline the entire book based on the talk, which I'd already spent a huge amount of time thinking about and organising. Then I did a full outline of the arguments and structures. Then I trained GPT-5 on my writing style. The way I did it – which I fully describe in the introduction to the book – was that I'd handle all the framing: the full introduction, the argument, the structure. But if there was a section where, for a few paragraphs, I was summarising a huge field of data, even something I knew well, I'd give GPT-5 the intro sentence and say, “In my writing style, prepare four paragraphs on this.” For example, I might write: “AI has the potential to see us humans like we humans see ant colonies.” Then I'd say, “Give me four paragraphs on the relationship between the individual and the collective in ant colonies.” I could have written those four paragraphs myself, but it would've taken a month to read the life's work of E.O. Wilson and then write them. GPT-5 wrote them in seconds or minutes, in its thinking mode. I'd then say, “It's not quite right – change this, change that,” and we'd go back and forth three or four times. Then I'd edit the whole thing and put it into the text. So this book that I could have written on my own in a year, I wrote a first draft of with GPT-5 as my named co-author in two days. The whole project will take about six months from start to finish, and I'm having massive human editing – multiple edits from me, plus a professional editor. It's not a magic AI button. But I feel strongly about listing GPT-5 as a co-author because I've written it differently than previous books. I'm a huge believer in the old-fashioned lone author struggling and suffering – that's in my novels, and in Virtuoso I explore that. But other forms are going to emerge, just like video games are a creative, artistic form deeply connected to technology. The novel hasn't been around forever – the current format is only a few centuries old – and forms are always changing. There are real opportunities for authors, and there will be so much crap flooding the market because everybody can write something and put it up on Amazon. But I think there will be a very special place for thoughtful human authors who have an idea of what humans do at our best, and who translate that into content other humans can enjoy. Traditional vs Indie: Why This Book Will Be Self-Published Jo: I'm interested – you mentioned that it's your named co-author. Is this book going through a traditional publisher, and what do they think about that? Or are you going to publish it yourself? Jamie: It's such a smart question. What I found quickly is that when you get to be an author later in your career, you have all the infrastructure – a track record, a fantastic agent, all of that. But there were two things that were really important to me here: I wanted to get this book out really fast – six months instead of a year and a half. It was essential to me to have GPT-5 listed as my co-author, because if it were just my name, I feel like it would be dishonest. Readers who are used to reading my books – I didn't want to present something different than what it was. I spoke with my agent, who I absolutely love, and she said that for this particular project it was going to be really hard in traditional publishing. So I did a huge amount of research, because I'd never done anything in the self-publishing world before. I looked at different models. There was one hybrid model that's basically the same as traditional, but you pay for the things the publisher would normally pay for. I ended up not doing that. Instead, I decided on a self-publishing route where I disaggregated the publishing process. I found three teams: one for producing the book, one for getting the book out into the world, and a smaller one for the audiobook. I still believe in traditional publishing – there's a lot of wonderful human value-add. But some works just don't lend themselves to traditional publishing. For this book, which is called The AI Ten Commandments, that's the path I've chosen. Jo: And when's that out? I think people will be interested. Jamie: April 26th. Those of us used to traditional publishing think, “I've finished the book, sold the proposal, it'll be out any day now,” and then it can be a year and a half. It's frustrating. With this, the process can be much faster because it's possible to control more of the variables. But the key – as I was saying – is to make sure it's as good a book as everything else you've written. It's great to speed up, but you don't want to compromise on quality. The Coming Flood of Excellent AI-Generated Work Jo: Yeah, absolutely. We're almost out of time, but I want to come back to your “flood of crap” and the “AI slop” idea that's going around. Because you are working with GPT-5 – and I do as well, and I work with Claude and Gemini – and right now there are still issues. Like you said about referencing, there are still hallucinations, though fewer. But fast-forward two, five years: it's not a flood of crap. It's a flood of excellent. It's a flood of stuff that's better than us. Jamie: We're humans. It's better than us in certain ways. If you have farm machinery, it's better than us at certain aspects of farming. I'm a true humanist. I think there will be lots of things machines do better than us, but there will be tons of things we do better than them. There's a reason humans still care about chess, even though machines can beat humans at chess. Some people are saying things I fully disagree with, like this concept of AGI – artificial general intelligence – where machines do everything better than humans. I've summarised my position in seven letters: “AGI is BS.” The only way you can believe in AGI in that sense is if your concept of what a human is and what a human mind is is so narrow that you think it's just a narrow range of analytical skills. We are so much more than that. Humans represent almost four billion years of embodied evolution. There's so much about ourselves that we don't know. As incredible as these machines are and will become, there will always be wonderful things humans can do that are different from machines. What I always tell people is: whatever you're doing, don't be a second-rate machine. Be a first-rate human. If you're doing something and a machine is doing that thing much better than you, then shift to something where your unique capacities as a human give you the opportunity to do something better. So yes, I totally agree that the quality of AI-generated stuff will get better. But I think the most creative and successful humans will be the ones who say, “I recognise that this is creating new opportunities, and I'm going to insert my core humanity to do something magical and new.” People are “othering” these technologies, but the technologies themselves are magnificent human-generated artefacts. They're not alien UFOs that landed here. It's a scary moment for creatives, no doubt, because there are things all of us did in the past that machines can now do really well. But this is the moment where the most creative people ask themselves, “What does it mean for me to be a great human?” The pat answers won't apply. In my Virtuoso novel I explore that a lot. The idea that “machines don't do creativity” – they will do incredible creativity; it just won't be exactly human creativity. We will be potentially huge beneficiaries of these capabilities, but we really have to believe in and invest in the magic of our core humanity. Where to Find Jamie and His Books Jo: Brilliant. So where can people find you and your books online? Jamie: Thank you so much for asking. My website is jamiemetzl.com – and my books are available everywhere. Jo: Fantastic. Thanks so much for your time, Jamie. That was great. Jamie: Thank you, Joanna.The post Writing The Future, And Being More Human In An Age of AI With Jamie Metzl first appeared on The Creative Penn.
This week on The Broski Report, Fearless Leader Brittany Broski answers journal prompts, discusses the age of brainrot, and analyzes trends in the horror genre. Watch The Broski Report AD FREE: https://patreon.com/broskireport The OFFICIAL Songs of The Week Playlist: https://open.spotify.com/playlist/3ULrcEqO2JafGZPeonyuje?si=061c5c0dd4664f01