Podcasts about Yale school

Retired federal judge Nancy Gertner is among dozens of former judges calling out the targeted and intentional deterioration of the rule of law in the U.S. court systemAndrea Cabral, former public safety secretary, discusses Trump's targeting of Somali migrants including Rep. Ilhan OmarDr. Megan Ranney, dean of Yale School of Public Health, discusses myriad public health issues: a vaccine advisory panel meeting today, the latest on mass shootings/gun violence, and restoring trust in public health/scientific institutionsCongressman Bill Keating discusses Admiral Bradley's appearance before the Senate to answer questions about the Sept. 2 boat strikesAdam Gardner & David Schnieder reunite in Studio 3 as The LeeVees, their Hanukkah themed band

In this episode of the Brain and Life podcast, Dr. Daniel Correa is joined Emmy award-winning broadcaster Mark McEwen. Mark shares his inspiring journey of recovery after suffering a stroke at the age of 52, which led to aphasia. He discusses his broadcasting career, the challenges he faced during recovery, and the importance of hope and resilience. Dr. Correa is then joined by Dr. Rachel Forman, a stroke neurologist and Assistant Professor of Neurology at Yale School of Medicine. Dr. Forman explains stroke risk factors, the importance of awareness, community health initiatives, and access to healthcare to prevent these life-altering events.   Articles Mentioned Stamp Out Stroke Get Smart about Stroke Navigating the Complexities of Stroke   Other Brain & Life Podcast Episodes on These Topics Understanding Stroke with Dr. Laurel Cherian Solving the Stroke with Will Shortz Matt and Kanlaya Cauli on Rebuilding Life After Stroke   We want to hear from you! Have a question or want to hear a topic featured on the Brain & Life Podcast? ·       Record a voicemail at 612-928-6206 ·       Email us at BLpodcast@brainandlife.org   Social Media:   Guest: Dr. Rachel Forman @yaleneurology Hosts: Dr. Daniel Correa @neurodrcorrea; Dr. Katy Peters @KatyPetersMDPhD

Howie and Harlan are joined by Sudhakar Nuti to discuss his work improving healthcare for homeless New Yorkers, as a street-medicine doctor and a population-health leader at NYC Health + Hospitals. Harlan reports on a proposed law that would cut off funding for U.S. scientists who collaborate with colleagues in China; Howie provides updates on the measles outbreak and a leaked FDA memo claiming that COVID-19 vaccines have killed 10 children. Show notes: Science Across Borders Subtitle C—SAFE Research Act "U.S. Congress considers sweeping ban on Chinese collaborations" Sudhakar Nuti NYC Health + Hospitals Street Medicine Institute "Health Care beyond Clinic Walls—Sustaining and Scaling Up Street Medicine" NYC Health + Hospitals: Street Health Outreach & Wellness Mobile Units "Graduate and professional students tackle food insecurity" California Depart of Public Health: Xylazine Measles CDC: Measles Cases and Outbreaks "Tracking U.S. Measles Outbreaks" World Health Organization: Weekly Epidemiological Record, 2025, vol. 100, no. 48 "Winning against measles: five charts that tell a remarkable 24-year story" "Measles deaths down 88% since 2000, but cases surge" FDA Leak "Experts say top FDA official's claim that Covid vaccines caused kids' deaths requires more evidence" "FDA's Prasad tells staffers agency plans to get tougher on vaccine regulation, blames child deaths on COVID shots" "Thoughts on Vinay Prasad's Leaked Email" "Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021" "Fulminant Myocarditis and Cardiogenic Shock Following COVID-19 Infection Versus COVID-19 Vaccination: A Systematic Literature Review" In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings. Email Howie and Harlan comments or questions.  

In a world of constant noise, speed, and digital overwhelm, how do we reclaim our inner stability and thrive?This week on The Flourishing Edge, Ashish Kothari welcomes Emma Seppala, Yale School of Management faculty member, bestselling author of Sovereign and The Happiness Track, and pioneering researcher in well-being science.Together they explore what it truly means to be sovereign—to live with awareness, agency, and mastery over one's mind and emotions—even amid the chaos of technology, AI, and nonstop change. Emma shares groundbreaking research on breathing, intuition, and emotional regulation, revealing how ancient contemplative wisdom meets modern neuroscience to help us flourish in work and life.

Dr. Nicola Hawley is an Associate Professor of Epidemiology at the Yale School of Public Health, where she also holds a secondary appointment in Anthropology. She serves as Associate Director for Dissemination and Implementation Science at the Yale Center for Clinical Investigation. Trained as a human biologist, Dr. Hawley is an internationally recognized expert in maternal and child health, with a focus on how early life experiences, from pregnancy through childhood, shape long-term risks for obesity and chronic disease. Her research bridges epidemiology, anthropology, and global health, using community-engaged and culturally grounded approaches to improve health outcomes in under-resourced and Indigenous settings. Much of her work centers in the Pacific, particularly in Sāmoa and American Sāmoa, where she leads NIH- and PCORI-funded studies on gestational and Type 2 diabetes, obesity prevention, and intergenerational health. She's also deeply committed to mentorship, helping train the next generation of global health and maternal-child health researchers. ------------------------------ Find the work discussed in this episode: Heinsberg LW, Loia M, Tasele S, Faasalele-Savusa K, Carlson JC, Anesi S, et al. (2025) Study protocol for the Health Outcomes in Pregnancy and Early Childhood (HOPE) Study: A mother-infant study in American Samoa. PLoS One 20(9): e0326644. https://doi.org/10.1371/journal.pone.0326644 ------------------------------ Contact the Sausage of Science Podcast and the Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Chris Lynn, Co-Host Website: cdlynn.people.ua.edu/, E-mail: cdlynn@ua.edu, Twitter:@Chris_Ly Courtney Manthey, Guest-Co-Host, Website: holylaetoli.com/ E-mail: cpierce4@uccs.edu, Twitter: @HolyLaetoli Anahi Ruderman, SoS Co-Producer, HBA Junior Fellow, E-mail: ruderman@cenpat-conicet.gob.ar

In this special episode, Kevin Berry sits down with Kerri Raissian, Senior Research Scientist at the Yale School of Public Health, Kenny Barlow from Regal Products, and WTTA founder Mike Sodini to recap a week that moved the conversation forward in meaningful ways. The National Research Conference for the Prevention of Firearm-Related Harms brought together researchers, public health leaders, industry partners, clinicians, and advocates who all share a common goal. Reduce negative outcomes and save lives.For the first time, WTTA and the ROOTS initiative were represented on the exhibitor floor. The response was overwhelmingly positive. Attendees were curious, supportive, and eager to learn how voluntary secure storage, mental health tools, and trusted community partnerships fit into the broader prevention landscape. Our team heard again and again how important it was to have firearm owners and industry voices present, willing to listen and willing to engage in good faith.In this conversation, we break down key themes from the conference, share insights from panels and hallway conversations, and talk about what it means when different perspectives finally have a chance to connect. This episode highlights why cultural understanding matters, what ROOTS is building, and how collaborations across disciplines can create practical, real-world solutions that help families, communities, and firearm owners.Send us a text Walk the Talk America would like to thank our partners who make these conversations possible and want to highlight our top two partner tiers below! Platinum Tier:RugerArmscorGold Tier:NASGWLipsey'sDavidson's

Strengthening service line performance requires a strong foundation in primary care, which remains central to delivering effective value-based care. Yet, the landscape of primary care delivery is marked by significant challenges including workforce shortages, provider burnout, administrative burdens, and increasing barriers to patient access. In this episode of Value-Based Care Insights, host Daniel J. Marino kicks off a new series exploring specialty service lines by starting with the primary care service line. He is joined by Dr. Sarita Soares, Program Director for the Yale Primary Care Internal Medicine Residency Program, and Dr. Brad Richards, Executive Director of the Yale Primary Care Internal Medicine Residency Program and Associate Professor of Medicine at the Yale School of Medicine. Together, they discuss the shifting dynamics of primary care, the growing integration of behavioral health, the role of technology in improving access, and what healthcare leaders can do to better support providers and patients in this changing environment.

European thinkers once divided humanity into distinct "races". The idea stuck, even if the science moved on. The shape of humanity, it turned out, is far messier than the old race theorists ever imagined.This much is well known.Still , genetics does study different human "populations". Biological differences between these populations are reported every day. So have we simply changed words? Has anything really changed?Yes, everything has changed. To explain why, I'm glad to have Diyendo Massilani on the show.Trained in France and Gabon, Massilani runs a lab at the Yale School of Medicine, where he studies ancient DNA and human adaptations. This fall, his lab has produced one of the most interesting analysis of human biodiversity that I have ever seen. I'm proud to feature it on the podcast before publication. Our conversation begins from the counter-intuitive implications of the Out of Africa theory, and its significance for ideas about race. We then discuss Massilani's own analysis about how the level of genetic differences between modern-day humans.As always, we finish with my guest's reflections on humanity. DECODING OUR STORYThis is episode 2 in the "Decoding Our Story" mini-series, recorded live at the Salk Institute's CARTA symposium on ancient DNA. The other episodes are:"The Neanderthal Mirror: Latest Findings About the Lines Between Us" ~ David Gokhman (published)"Restless Humanity: The Epic Migrations Into America, Polynesia, and... Beyond?" ~ Andrés Moreno-Estrada (4th of Dec)FACT CHECKINGNo errors have been found as of now. If you find an error in this or other episodes, get in touch via the form below.LINKSArticles and essays: ⁠⁠OnHumans.Substack.com⁠⁠Support: ⁠⁠Patreon.com/OnHumans⁠⁠Contact Form: ⁠⁠https://forms.gle/h5wcmefuwvD6asos8⁠⁠CARTA symposium⁠The Massilani lab⁠KEYWORDSHuman evolution | Human origins | Anthropogeny | Anthropology | Paleoanthropology | Genetics | Homo sapiens | Ancient DNA | Comparative genetics | Human biodiversity | Admixture | Archaeogenetics | Archaeology | Mbuti | Papuans | Neanderthals

Episode 141 - Reimagining Primary Care Service Lines to Drive Growth and Value Strengthening service line performance requires a strong foundation in primary care, which remains central to delivering effective value-based care. Yet, the landscape of primary care delivery is marked by significant challenges including workforce shortages, provider burnout, administrative burdens, and increasing barriers to patient access. On this episode Dan kicks off a new series exploring specialty service lines by starting with the primary care service line. He is joined by Dr. Sarita Soares, Program Director for the Yale Primary Care Internal Medicine Residency Program, and Dr. Brad Richards, Executive Director of the Yale Primary Care Internal Medicine Residency Program and Associate Professor of Medicine at the Yale School of Medicine. Together, they discuss the shifting dynamics of primary care, the growing integration of behavioral health, the role of technology in improving access, and what healthcare leaders can do to better support providers and patients in this changing environment. To stream our Station live 24/7 visit www.HealthcareNOWRadio.com or ask your Smart Device to “….Play Healthcare NOW Radio”. Find all of our network podcasts on your favorite podcast platforms and be sure to subscribe and like us. Learn more at www.healthcarenowradio.com/listen

Howie and Harlan are joined by Peter Hotez, a vaccine expert and an outspoken opponent of health misinformation, to discuss vaccine skepticism and the forces—from wellness influencers to HHS secretary Robert F. Kennedy Jr.—that amplify it. Harlan reports on research reinforcing the link between social media and mental illness; Howie highlights two potential areas of common ground with the administration's health policy.  Show notes: Social Media and Mental Health "Social Media Detox and Youth Mental Health" "Study Finds Mental Health Benefit to One-Week Social Media Break" Peter Hotez Peter Hotez: Science Under Siege: How to Fight the Five Most Powerful Forces That Threaten Our World Peter Hotez: Vaccines Did Not Cause Rachel's Autism: My Journey as a Vaccine Scientist, Pediatrician, and Autism Dad "Scientist pressured by Musk and Rogan to debate RFK Jr over anti-vaccine misinformation says he won't be part of 'Jerry Springer' show" Peter Hotez on X "Kennedy Says He Told C.D.C. to Change Website's Language on Autism and Vaccines" "Wakefield's article linking MMR vaccine and autism was fraudulent" "Four vaccine myths and where they came from" "Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism" "Risk of Autism after Prenatal Topiramate, Valproate, or Lamotrigine Exposure" "Data investigation: Childhood vaccination rates are backsliding across the U.S." "South Carolina's Measles Outbreak Shows Chilling Effect of Vaccine Misinformation" "How a measles outbreak overwhelmed a small West Texas town" "How polio came back to New York for the first time in decades, silently spread and left a patient paralyzed" "Third infant in Kentucky dies of whooping cough as national cases stay high for second year in a row" "Kennedy minimizes measles outbreak in wake of Texas death" "RFK Jr. claims 'leaky' measles vaccine wanes over time. Scientists say he's wrong." "RFK Jr. claims measles can be treated with vitamin A, linked to poor diet. Here's what science says" "The Surprise Ending to the Trump-Mamdani Buddy Movie Has Heads Spinning" "Operation Warp Speed was one of Trump's biggest achievements. Then came RFK Jr. and vaccine skeptics" Health & Veritas Episode 196: The Cost Curve, Flu, and Other News "Weaponized Health Communication: Twitter Bots and Russian Trolls Amplify the Vaccine Debate" ACA Subsidies "Trump was going to roll out a health care plan. Then Republicans weighed in." "Trump Is Considering a Push to Extend Obamacare Subsidies" Site-Neutral Payment "The Trump Administration Moves Forward with Medicare Site-Neutral Payment Reform" "Five Things to Know About Medicare Site-Neutral Payment Reforms" In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings. Email Howie and Harlan comments or questions.

Send us a textDr. Sadie Elisseou, MD is Founder and CEO of Trauma-Informed Practices, LLC (https://www.sadie-elisseou.com/). Dr. Elisseou is a nationally recognized physician-educator and one of the leading voices in trauma-informed care, a strategic framework for supporting survivors of physical, sexual, psychological, and structural traumas. Dr. Elisseou is a board-certified primary care physician, who received her B.A. and M.D. at Brown University and completed residency and chief residency at Yale School of Medicine. She a practicing physician in the VA healthcare system, and an instructor at Harvard Medical School and Boston University School of Medicine, where she has become widely known for transforming how clinicians understand and care for patients with trauma histories.Dr. Elisseou is the co-developer of some of the country's most widely adopted trauma-informed physical exam trainings, helping thousands of healthcare professionals integrate compassion, safety, and empathy into routine clinical encounters. Her work has been implemented across the VA, community health centers, academic medical systems, and national professional societies.Dr. Elisseou is also the co-founder of the National Veterans Health Administration TIC Collaborative, a member of the Trauma Informed Health Care, Education and Research (TIHCHER) collaborative, and a member of the Harvard Medical School TIC Steering Committee. She is invited to speak about TIC for broad audiences including the Substance Abuse and Mental Health Services Administration (SAMHSA), the Association of American Medical Colleges (AAMC), disaster relief organizations, and health officials in developing nations. She has also been named an Ambassador of the Dr. Lorna Breen Heroes Foundation. #SadieElisseou #TraumaInformedPractices #BrownUniversity #YaleSchoolOfMedicine #HarvardMedicalSchool #BostonUniversitySchoolOfMedicine #VeteransHealthAdministration #Trauma #TraumaInformedCare #ReTraumatization #SubstanceAbuseAndMentalHealthServicesAdministration #SAMHSA #UniversalTraumaPrecautions #ClinicianBurnout #EmergencyDepartment #Telehealth #BodySizeDiversity #Healing #Resilience #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #STEM #Innovation #Technology #Science #ResearchSupport the show

Howie and Harlan are joined by Peter Hotez, a vaccine expert and an outspoken opponent of health misinformation, to discuss vaccine skepticism and the forces—from wellness influencers to HHS secretary Robert F. Kennedy Jr.—that amplify it. Harlan reports on research reinforcing the link between social media and mental illness; Howie highlights two potential areas of common ground with the administration's health policy.  Show notes: Social Media and Mental Health "Social Media Detox and Youth Mental Health" "Study Finds Mental Health Benefit to One-Week Social Media Break" Peter Hotez Peter Hotez: Science Under Siege: How to Fight the Five Most Powerful Forces That Threaten Our World Peter Hotez: Vaccines Did Not Cause Rachel's Autism: My Journey as a Vaccine Scientist, Pediatrician, and Autism Dad "Scientist pressured by Musk and Rogan to debate RFK Jr over anti-vaccine misinformation says he won't be part of 'Jerry Springer' show" Peter Hotez on X "Kennedy Says He Told C.D.C. to Change Website's Language on Autism and Vaccines" "Wakefield's article linking MMR vaccine and autism was fraudulent" "Four vaccine myths and where they came from" "Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism" "Risk of Autism after Prenatal Topiramate, Valproate, or Lamotrigine Exposure" "Data investigation: Childhood vaccination rates are backsliding across the U.S." "South Carolina's Measles Outbreak Shows Chilling Effect of Vaccine Misinformation" "How a measles outbreak overwhelmed a small West Texas town" "How polio came back to New York for the first time in decades, silently spread and left a patient paralyzed" "Third infant in Kentucky dies of whooping cough as national cases stay high for second year in a row" "Kennedy minimizes measles outbreak in wake of Texas death" "RFK Jr. claims 'leaky' measles vaccine wanes over time. Scientists say he's wrong." "RFK Jr. claims measles can be treated with vitamin A, linked to poor diet. Here's what science says" "The Surprise Ending to the Trump-Mamdani Buddy Movie Has Heads Spinning" "Operation Warp Speed was one of Trump's biggest achievements. Then came RFK Jr. and vaccine skeptics" Health & Veritas Episode 196: The Cost Curve, Flu, and Other News "Weaponized Health Communication: Twitter Bots and Russian Trolls Amplify the Vaccine Debate" ACA Subsidies "Trump was going to roll out a health care plan. Then Republicans weighed in." "Trump Is Considering a Push to Extend Obamacare Subsidies" Site-Neutral Payment "The Trump Administration Moves Forward with Medicare Site-Neutral Payment Reform" "Five Things to Know About Medicare Site-Neutral Payment Reforms" In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings. Email Howie and Harlan comments or questions.

Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, the conversation brings the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—including Lyme disease and other tick-borne infections—to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to highlight leading scientists connecting infection, immune dysfunction, and cognitive decline. This episode features Dr. Sean Miller, a neuroscientist and co-investigator in the Logan Lab with a primary appointment at Yale School of Medicine, who is developing ways to non-invasively detect Alzheimer's-like pathology through the eye. Guest Sean Miller, PhD Co-Investigator, Logan Lab / Yale School of Medicine Dr. Sean Miller completed pre-doctoral work at Harvard Medical School, earned his PhD from Johns Hopkins University, and completed post-doctoral training at Stanford University. His research focuses on neurodegeneration, neuroglia, and early diagnostic strategies for Alzheimer's and related diseases. At the AlzPI & PCOM Symposium, Dr. Miller presented evidence showing that SARS-CoV-2 (COVID-19) infection can accelerate Alzheimer's-like pathology and that these changes can be detected non-invasively through retinal imaging. His findings suggest that amyloid-beta, a protein long associated with Alzheimer's disease, may also serve as part of the brain's antimicrobial defense system—trapping pathogens like a mesh or biofilm, but leading to damaging plaque buildup when overproduced. Key Discussion Points Dr. Miller describes how the COVID-19 virus can act as an infectious trigger for neuroinflammation and amyloid buildup, how the eye provides a unique window into the brain, and why early detection is essential to preventing neuron death. He shares how his lab's AI-enhanced retinal imaging research at Yale Eye Center is identifying amyloid and tau deposits in patients with long COVID-related brain fog—opening the possibility of routine eye exams doubling as early Alzheimer's screening tools. He explains potential therapeutic strategies, such as limiting amyloid production during infection flare-ups and enhancing clearance mechanisms afterward to reduce chronic plaque formation. The conversation also explores his scientific journey—from designing Alzheimer's drugs at Harvard and Johns Hopkins to realizing the need for early disease detection during his postdoc at Stanford—and how the pandemic inspired his focus on infection-induced neurodegeneration. “We believe neurons are exposed to pathogens in the central nervous system and respond by secreting amyloid-beta to trap them. Excessive plaque buildup from repeated or severe infections may be what drives long-term neurodegeneration.” — Dr. Sean Miller Why It Matters Dr. Miller's research connects infectious disease, ophthalmology, and neurology, providing a revolutionary new method to screen for early Alzheimer's-like changes non-invasively through the human eye. His work suggests that infections like COVID-19 may trigger the same protective—but damaging—immune responses implicated in chronic conditions such as Alzheimer's disease and infection-associated cognitive decline. About the Event The interview took place at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, held on October 3, 2025, at Ohio University in Dublin, Ohio. The event brought together more than 20 global researchers exploring how microbes, the microbiome, and the immune response contribute to Alzheimer's, dementia, PANS/PANDAS, and infection-associated chronic illnesses (IACI). Tick Boot Camp partnered with Ali Moresco and Nikki Schultek to share the voices of researchers advancing the field of infection-associated chronic illness. This episode is part of a multi-part Tick Boot Camp series highlighting how pathobiome and microbiome science are transforming the understanding of Lyme disease, infection, and neurodegeneration. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

In this episode, Kelly Brownell speaks with Jerold Mande, CEO of Nourish Science, adjunct professor at the Harvard School of Public Health, and former Deputy Undersecretary for Food Safety at the USDA. They discuss the alarming state of children's health in America, the challenges of combating poor nutrition, and the influence of the food industry on public policy. The conversation explores the parallels between the tobacco and food industries and proposes new strategies for ensuring children reach adulthood in good health. Mande emphasizes the need for radical changes in food policy and the role of public health in making these changes. Transcript So, you co-founded this organization along with Jerome Adams, Bill Frist and Thomas Grumbly, as we said, to ensure every child breaches age 18 at a healthy weight and in good metabolic health. That's a pretty tall order given the state of the health of youth today in America. But let's start by you telling us what inspired this mission and what does it look like to achieve this in today's food environment? I was trained in public health and also in nutrition and in my career, which has been largely in service of the public and government, I've been trying to advance those issues. And unfortunately over the arc of my career from when I started to now, particularly in nutrition and public health, it's just gotten so much worse. Indeed today Americans have the shortest lifespans by far. We're not just last among the wealthy countries, but we're a standard deviation last. But probably most alarming of all is how sick our children are. Children should not have a chronic disease. Yet in America maybe a third do. I did some work on tobacco at one point, at FDA. That was an enormous success. It was the leading cause of death. Children smoked at a higher rate, much like child chronic disease today. About a third of kids smoked. And we took that issue on, and today it's less than 2%. And so that shows that government can solve these problems. And since we did our tobacco work in the early '90s, I've changed my focus to nutrition and public health and trying to fix that. But we've still made so little progress. Give us a sense of how far from that goal we are. So, if the goal is to make every child reaching 18 at a healthy weight and in good metabolic health, what percentage of children reaching age 18 today might look like that? It's probably around a half or more, but we're not quite sure. We don't have good statistics. One of the challenges we face in nutrition is, unfortunately, the food industry or other industries lobby against funding research and data collection. And so, we're handicapped in that way. But we do know from the studies that CDC and others have done that about 20% of our children have obesity about a similar number have Type 2 diabetes or the precursors, pre-diabetes. You and I started off calling it adult-onset diabetes and they had to change that name to a Type 2 because it's becoming so common in kids. And then another disease, fatty liver disease, really unthinkable in kids. Something that the typical pediatrician would just never see. And yet in the last decade, children are the fastest growing group. I think we don't know an exact number, but today, at least a third, maybe as many as half of our children have a chronic disease. Particularly a food cause chronic disease, or the precursors that show they're on the way. I remember probably going back about 20 years, people started saying that we were seeing the first generation of American children that would lead shorter lives than our parents did. And what a terrible legacy to leave our children. Absolutely. And that's why we set that overarching goal of ensuring every child reaches age 18 in good metabolic health. And the reason we set that is in my experience in government, there's a phrase we all use - what gets measured gets done. And when I worked at FDA, when I worked at USDA, what caught my attention is that there is a mission statement. There's a goal of what we're trying to achieve. And it's ensuring access to healthy options and information, like a food label. Now the problem with that, first of all, it's failed. But the problem with that is the bureaucrats that I oversaw would go into a supermarket, see a produce section, a protein section, the food labels, which I worked on, and say we've done our job. They would check those boxes and say, we've done it. And yet we haven't. And if we ensured that every child reaches age 18 at a healthy weight and good metabolic health, if the bureaucrats say how are we doing on that? They would have to conclude we're failing, and they'd have to try something else. And that's what we need to do. We need to try radically different, new strategies because what we've been doing for decades has failed. You mentioned the food industry a moment ago. Let's talk about that in a little more detail. You made the argument that food companies have substituted profits for health in how they design their products. Explain that a little bit more, if you will. And tell us how the shift has occurred and what do you think the public health cost has been? Yes, so the way I like to think of it, and your listeners should think of it, is there's a North star for food design. And from a consumer standpoint, I think there are four points on the star: taste, cost, convenience, and health. That's what they expect and want from their food. Now the challenge is the marketplace. Because that consumer, you and I, when we go to the grocery store and get home on taste, cost, and convenience, if we want within an hour, we can know whether the food we purchased met our standard there. Or what our expectations were. Not always for health. There's just no way to know in a day, a week, a month, even in a year or more. We don't know if the food we're eating is improving and maintaining our health, right? There should be a definition of food. Food should be what we eat to thrive. That really should be the goal. I borrowed that from NASA, the space agency. When I would meet with them, they said, ' Jerry, it's important. Right? It's not enough that people just survive on the food they eat in space. They really need to thrive.' And that's what WE need to do. And that's really what food does, right? And yet we have food, not only don't we thrive, but we get sick. And the reason for that is, as I was saying, the marketplace works on taste, cost and convenience. So, companies make sure their products meet consumer expectation for those three. But the problem is on the fourth point on the star: on health. Because we can't tell in even years whether it's meeting our expectation. That sort of cries out. You're at a policy school. Those are the places where government needs to step in and act and make sure that the marketplace is providing. That feedback through government. But the industry is politically strong and has prevented that. And so that has left the fourth point of the star open for their interpretation. And my belief is that they've put in place a prop. So, they're making decisions in the design of the product. They're taste, they gotta get taste right. They gotta get cost and convenience right. But rather than worrying what does it do to your health? They just, say let's do a profit. And that's resulted in this whole category of food called ultra-processed food (UPF). I actually believe in the future, whether it's a hundred years or a thousand years. If humanity's gonna thrive we need manmade food we can thrive on. But we don't have that. And we don't invest in the science. We need to. But today, ultra-processed food is manmade food designed on taste, cost, convenience, and then how do we make the most money possible. Now, let me give you one other analogy, if I could. If we were CEOs of an automobile company, the mission is to provide vehicles where people can get safely from A to point B. It's the same as food we can thrive on. That is the mission. The problem is that when the food companies design food today, they've presented to the CEO, and everyone gets excited. They're seeing the numbers, the charts, the data that shows that this food is going to meet, taste, cost, convenience. It's going to make us all this money. But the CEO should be asking this following question: if people eat this as we intend, will they thrive? At the very least they won't get sick, right? Because the law requires they can't get sick. And if the Midmanagers were honest, they'd say here's the good news boss. We have such political power we've been able to influence the Congress and the regulatory agencies. That they're not going to do anything about it. Taste, cost, convenience, and profits will work just fine. Couldn't you make the argument that for a CEO to embrace that kind of attitude you talked about would be corporate malpractice almost? That, if they want to maximize profits then they want people to like the food as much as possible. That means engineering it in ways that make people overeat it, hijacking the reward pathways in the brain, and all that kind of thing. Why in the world would a CEO care about whether people thrive? Because it's the law. The law requires we have these safety features in cars and the companies have to design it that way. And there's more immediate feedback with the car too, in terms of if you crashed right away. Because it didn't work, you'd see that. But here's the thing. Harvey Wiley.He's the founder of the food safety programs that I led at FDA and USDA. He was a chemist from academia. Came to USDA in the late 1800s. It was a time of great change in food in America. At that point, almost all of families grew their own food on a farm. And someone had to decide who's going to grow our food. It's a family conversation that needed to take place. Increasingly, Americans were moving into the cities at that time, and a brand-new industry had sprung up to feed people in cities. It was a processed food industry. And in order to provide shelf stable foods that can offer taste, cost, convenience, this new processed food industry turned to another new industry, a chemical industry. Now, it's hard to believe this, but there was a point in time that just wasn't an industry. So these two big new industries had sprung up- processed food and chemicals. And Harvey Wiley had a hypothesis that the chemicals they were using to make these processed foods were making us sick. Indeed, food poisoning back then was one of the 10 leading causes of death. And so, Harvey Wiley went to Teddy Roosevelt. He'd been trying for years within the bureaucracy and not making progress. But when Teddy Roosevelt came in, he finally had the person who listened to him. Back then, USDA was right across from the Washington Monument to the White House. He'd walk right over there into the White House and met with Teddy Roosevelt and said, ' this food industry is making us sick. We should do something about it.' And Teddy Roosevelt agreed. And they wrote the laws. And so I think what your listeners need to understand is that when you look at the job that FDA and USDA is doing, their food safety programs were created to make sure our food doesn't make us sick. Acutely sick. Not heart disease or cancer, 30, 40 years down the road, but acutely sick. No. I think that's absolutely the point. That's what Wiley was most concerned about at the time. But that's not the law they wrote. The law doesn't say acutely ill. And I'll give you this example. Your listeners may be familiar with something called GRAS - Generally Recognized as Safe. It's a big problem today. Industry co-opted the system and no longer gets approval for their food additives. And so, you have this Generally Recognized as Safe system, and you have these chemicals and people are worried about them. In the history of GRAS. Only one chemical has FDA decided we need to get that off the market because it's unsafe. That's partially hydrogenated oils or trans-fat. Does trans-fat cause acute illness? It doesn't. It causes a chronic disease. And the evidence is clear. The agency has known that it has the responsibility for both acute and chronic illness. But you're right, the industry has taken advantage of this sort of chronic illness space to say that that really isn't what you should be doing. But having worked at those agencies, I don't think they see it that way. They just feel like here's the bottom line on it. The industry uses its political power in Congress. And it shapes the agency's budget. So, let's take FDA. FDA has a billion dollars with a 'b' for food safety. For the acute food safety, you're talking about. It has less than 25 million for the chronic disease. There are about 1400 deaths a year in America due to the acute illnesses caused by our food that FDA and USDA are trying to prevent. The chronic illnesses that we know are caused by our food cause 1600 maybe a day. More than that of the acute every day. Now the agency should be spending at least half its time, if not more, worrying about those chronic illness. Why doesn't it? Because the industry used their political power in Congress to put the billion dollars for the acute illness. That's because if you get acutely ill, that's a liability concern for them. Jerry let's talk about the political influence in just a little more detail, because you're in a unique position to tell us about this because you've seen it from the inside. One mechanism through which industry might influence the political process is lobbyists. They hire lobbyists. Lobbyists get to the Congress. People make decisions based on contributions and things like that. Are there other ways the food industry affects the political process in addition to that. For example, what about the revolving door issue people talk about where industry people come into the administrative branch of government, not legislative branch, and then return to industry. And are there other ways that the political influence of the industry has made itself felt? I think first and foremost it is the lobbyists, those who work with Congress, in effect. Particularly the funding levels, and the authority that the agencies have to do that job. I think it's overwhelmingly that. I think second, is the influence the industry has. So let me back up to that a sec. As a result of that, we spend very little on nutrition research, for example. It's 4% of the NIH budget even though we have these large institutes, cancer, heart, diabetes, everyone knows about. They're trying to come up with the cures who spend the other almost 50 billion at NIH. And so, what happens? You and I have both been at universities where there are nutrition programs and what we see is it's very hard to not accept any industry money to do the research because there isn't the federal money. Now, the key thing, it's not an accident. It's part of the plan. And so, I think that the research that we rely on to do regulation is heavily influenced by industry. And it's broad. I've served, you have, others, on the national academies and the programs. When I've been on the inside of those committees, there are always industry retired scientists on those committees. And they have undue influence. I've seen it. Their political power is so vast. The revolving door, that is a little of both ways. I think the government learns from the revolving door as well. But you're right, some people leave government and try to undo that. Now, I've chosen to work in academia when I'm not in government. But I think that does play a role, but I don't think it plays the largest role. I think the thing that people should be worried about is how much influence it has in Congress and how that affects the agency's budgets. And that way I feel that agencies are corrupted it, but it's not because they're corrupted directly by the industry. I think it's indirectly through congress. I'd like to get your opinion on something that's always relevant but is time sensitive now. And it's dietary guidelines for America. And the reason I'm saying it's time sensitive is because the current administration will be releasing dietary guidelines for America pretty soon. And there's lots of discussion about what those might look like. How can they help guide food policy and industry practices to support healthier children and families? It's one of the bigger levers the government has. The biggest is a program SNAP or food stamps. But beyond that, the dietary guidelines set the rules for government spending and food. So, I think often the way the dietary guidelines are portrayed isn't quite accurate. People think of it in terms of the once (food) Pyramid now the My Plate that's there. That's the public facing icon for the dietary guidelines. But really a very small part. The dietary guidelines are meant to help shape federal policy, not so much public perception. It's there. It's used in education in our schools - the (My) Plate, previously the (Food) Pyramid. But the main thing is it should shape what's served in government feeding programs. So principally that should be SNAP. It's not. But it does affect the WIC program- Women, Infants and Children, the school meals program, all of the military spending on food. Indeed, all spending by the government on food are set, governed by, or directed by the dietary guidelines. Now some of them are self-executing. Once the dietary guidelines change the government changes its behavior. But the biggest ones are not. They require rulemaking and in particular, today, one of the most impactful is our kids' meals in schools. So, whatever it says in these dietary guidelines, and there's reason to be alarmed in some of the press reports, it doesn't automatically change what's in school meals. The Department of Agriculture would have to write a rule and say that the dietary guidelines have changed and now we want to update. That usually takes an administration later. It's very rare one administration could both change the dietary guidelines and get through the rulemaking process. So, people can feel a little reassured by that. So, how do you feel about the way things seem to be taking shape right now? This whole MAHA movement Make America Healthy Again. What is it? To me what it is we've reached this tipping point we talked about earlier. The how sick we are, and people are saying, 'enough. Our food shouldn't make us sick at middle age. I shouldn't have to be spending so much time with my doctor. But particularly, it shouldn't be hard to raise my kids to 18 without getting sick. We really need to fix that and try to deal with that.' But I think that the MAHA movement is mostly that. But RFK and some of the people around them have increasingly claimed that it means some very specific things that are anti-science. That's been led by the policies around vaccine that are clearly anti-science. Nutrition is more and more interesting. Initially they started out in the exact right place. I think you and I could agree the things they were saying they need to focus on: kids, the need to get ultra-processed food out of our diets, were all the right things. In fact, you look at the first report that RFK and his team put out back in May this year after the President put out an Executive Order. Mostly the right things on this. They again, focus on kids, ultra-processed food was mentioned 40 times in the report as the root cause for the very first time. And this can't be undone. You had the White House saying that the root cause of our food-caused chronic disease crisis is the food industry. That's in a report that won't change. But a lot has changed since then. They came out with a second report where the word ultra-processed food showed up only once. What do you think happened? I know what happened because I've worked in that setting. The industry quietly went to the White House, the top political staff in the White House, and they said, you need to change the report when you come out with the recommendations. And so, the first report, I think, was written by MAHA, RFK Jr. and his lieutenants. The second report was written by the White House staff with the lobbyists of the food industry. That's what happened. What you end up with is their version of it. So, what does the industry want? We have a good picture from the first Trump administration. They did the last dietary guidelines and the Secretary of Agriculture, then Sonny Perdue, his mantra to his staff, people reported to me, was the industries- you know, keep the status quo. That is what the industry wants is they really don't want the dietary guidelines to change because then they have to reformulate their products. And they're used to living with what we have and they're just comfortable with that. For a big company to reformulate a product is a multi-year effort and cost billions of dollars and it's just not what they want to have to do. Particularly if it's going to change from administration to administration. And that is not a world they want to live in. From the first and second MAHA report where they wanted to go back to the status quo away from all the radical ideas. It'll be interesting to see what happens with dietary guidelines because we've seen reports that RFK Jr. and his people want to make shifts in policies. Saying that they want to go back to the Pyramid somehow. There's a cartoon on TV, South Park, I thought it was produced to be funny. But they talked about what we need to do is we need to flip the Pyramid upside down and we need to go back to the old Pyramid and make saturated fat the sort of the core of the diet. I thought it meant to be a joke but apparently that's become a belief of some people in the MAHA movement. RFK. And so, they want to add saturated fat back to our diets. They want to get rid of plant oils from our diets. There is a lot of areas of nutrition where the science isn't settled. But that's one where it is, indeed. Again, you go back only 1950s, 1960s, you look today, heart disease, heart attacks, they're down 90%. Most of that had to do with the drugs and getting rid of smoking. But a substantial contribution was made by nutrition. Lowering saturated fat in our diets and replacing it with plant oils that they're now called seed oils. If they take that step and the dietary guidelines come out next month and say that saturated fat is now good for us it is going to be just enormously disruptive. I don't think companies are going to change that much. They'll wait it out because they'll ask themselves the question, what's it going to be in two years? Because that's how long it takes them to get a product to market. Jerry, let me ask you this. You painted this picture where every once in a while, there'll be a glimmer of hope. Along comes MAHA. They're critical of the food industry and say that the diet's making us sick and therefore we should focus on different things like ultra-processed foods. In report number one, it's mentioned 40 times. Report number two comes out and it's mentioned only once for the political reasons you said. Are there any signs that lead you to be hopeful that this sort of history doesn't just keep repeating itself? Where people have good ideas, there's science that suggests you go down one road, but the food industry says, no, we're going to go down another and government obeys. Are there any signs out there that lead you to be more hopeful for the future? There are signs to be hopeful for the future. And number one, we talked earlier, is the success we had regulating tobacco. And I know you've done an outstanding job over the years drawing the parallels between what happened in tobacco and food. And there are good reasons to do that. Not the least of which is that in the 1980s, the tobacco companies bought all the big food companies and imparted on them a lot of their lessons, expertise, and playbook about how to do these things. And so that there is a tight link there. And we did succeed. We took youth smoking, which was around a 30 percent, a third, when we began work on this in the early 1990s when I was at FDA. And today it's less than 2%. It's one area with the United States leads the world in terms of what we've achieved in public health. And there's a great benefit that's going to come to that over the next generation as all of those deaths are prevented that we're not quite seeing yet. But we will. And that's regardless of what happens with vaping, which is a whole different story about nicotine. But this idea success and tobacco. The food industry has a tobacco playbook about how to addict so many people and make so much money and use their political power. We have a playbook of how to win the public health fight. So, tell us about that. What you're saying is music to my ears and I'm a big believer in exactly what you're saying. So, what is it? What does that playbook look like and what did we learn from the tobacco experience that you think could apply into the food area? There are a couple of areas. One is going to be leadership and we'll have to come back to that. Because the reason we succeeded in tobacco was the good fortune of having a David Kessler at FDA and Al Gore as Vice President. Nothing was, became more important to them than winning this fight against a big tobacco. Al Gore because his sister died at a young age of smoking. And David Kessler became convinced that this was the most important thing for public health that he could do. And keep in mind, when he came to FDA, it was the furthest thing from his mind. So, one of it is getting these kinds of leaders. Did does RFK Jr. and Marty McCarey match up to Al Gore? And we'll see. But the early signs aren't that great. But we'll see. There's still plenty of time for them to do this and get it right. The other thing is having a good strategy and policy about how to do it. And here, with tobacco, it was a complete stretch, right? There was no where did the FDA get authority over tobacco? And indeed, we eventually needed the Congress to reaffirm that authority to have the success we did. As we talked earlier, there's no question FDA was created to make sure processed food and the additives and processed food don't make us sick. So, it is the core reason the agency exists is to make sure that if there's a thing called ultra-processed food, man-made food, that is fine, but we have to thrive when we eat it. We certainly can't be made sick when we eat it. Now, David Kessler, I mentioned, he's put forward a petition, a citizens' petition to FDA. Careful work by him, he put months of effort into this, and he wrote basically a detailed roadmap for RFK and his team to use if they want to regulate ultra-processed stuff food. And I think we've gotten some, initially good feedback from the MAHA RFK people that they're interested in this petition and may take action on it. So, the basic thrust of the Kessler petition from my understanding is that we need to reconsider what's considered Generally Recognized as Safe. And that these ultra-processed foods may not be considered safe any longer because they produce all this disease down the road. And if MAHA responds positively initially to the concept, that's great. And maybe that'll have legs, and something will actually happen. But is there any reason to believe the industry won't just come in and quash this like they have other things? This idea of starting with a petition in the agency, beginning an investigation and using its authority is the blueprint we used with tobacco. There was a petition we responded, we said, gee, you raised some good points. There are other things we put forward. And so, what we hope to see here with the Kessler petition is that the FDA would put out what's called an advanced notice of a proposed rulemaking with the petition. This moves it from just being a petition to something the agency is saying, we're taking this seriously. We're putting it on the record ourselves and we want industry and others now to start weighing in. Now here's the thing, you have this category of ultra-processed food that because of the North Star I talked about before, because the industry, the marketplace has failed and gives them no incentive to make sure that we thrive, that keeps us from getting sick. They've just forgotten about that and put in place profits instead. The question is how do you get at ultra-processed food? What's the way to do it? How do you start holding the industry accountable? Now what RFK and the MAHA people started with was synthetic color additives. That wasn't what I would pick but, it wasn't a terrible choice. Because if you talk to Carlos Monteiro who coined the phrase ultra-processed food, and you ask him, what is an ultra-processed food, many people say it's this industrial creation. You can't find the ingredients in your kitchen. He agrees with all that, but he thinks the thing that really sets ultra-processed food, the harmful food, is the cosmetics that make them edible when they otherwise won't I've seen inside the plants where they make the old fashioned minimally processed food versus today's ultra-processed. In the minimally processed plants, I recognize the ingredients as food. In today's plants, you don't recognize anything. There are powders, there's sludges, there's nothing that you would really recognize as food going into it. And to make that edible, they use the cosmetics and colors as a key piece of that. But here's the problem. It doesn't matter if the color is synthetic or natural. And a fruit loop made with natural colors is just as bad for you as one made with synthetics. And indeed, it's been alarming that the agency has fast tracked these natural colors and as replacements because, cyanide is natural. We don't want to use that. And the whole approach has been off and it like how is this going to get us there? How is this focus on color additives going to get us there. And it won't. Yeah, I agree. I agree with your interpretation of that. But the thing with Kessler you got part of it right but the main thing he did is say you don't have to really define ultra-processed food, which is another industry ploy to delay action. Let's focus on the thing that's making us sick today. And that's the refined carbohydrates. The refined grains in food. That's what's most closely linked to the obesity, the diabetes we're seeing today. Now in the 1980s, the FDA granted, let's set aside sugar and white flour, for example, but they approved a whole slew of additives that the companies came forward with to see what we can add to the white flour and sugar to make it shelf stable, to meet all the taste, cost, and convenience considerations we have. And profit-making considerations we have. Back then, heart disease was the driving health problem. And so, it was easy to overlook why you didn't think that the these additives were really harmful. That then you could conclude whether Generally Recognized as Safe, which is what the agency did back then. What Kessler is saying is that what he's laid out in his petition is self-executing. It's not something that the agency grants that this is GRAS or not GRAS. They were just saying things that have historical safe use that scientists generally recognize it as safe. It's not something the agency decides. It's the universe of all of us scientists generally accept. And it's true in the '80s when we didn't face the obesity and diabetes epidemic, people didn't really focus on the refined carbohydrates. But if you look at today's food environment. And I hope you agree with this, that what is the leading driver in the food environment about what is it about ultra-processed food that's making us so sick? It's these refined grains and the way they're used in our food. And so, if the agency takes up the Kessler petition and starts acting on it, they don't have to change the designation. Maybe at some point they have to say some of these additives are no longer GRAS. But what Kessler's saying is by default, they're no longer GRAS because if you ask the scientists today, can we have this level of refined grains? And they'd say, no, that's just not Generally Recognized as Safe. So, he's pointing out that status, they no longer hold that status. And if the agency would recognize that publicly and the burden shifts where Wiley really always meant it to be, on the industry to prove that there are foods or things that we would thrive on, but that wouldn't make us sick. And so that's the key point that you go back to when you said, and you're exactly right that if you let the industry use their political power to just ignore health altogether and substitute profits, then you're right. Their sort of fiduciary responsibility is just to maximize profits and they can ignore health. If you say you can maximize profits, of course you're a capitalist business, but one of the tests you have to clear is you have to prove to us that people can thrive when they eat that. Thrive as the standard, might require some congressional amplification because it's not in the statute. But what is in the statute is the food can't make you sick. If scientists would generally recognize, would say, if you eat this diet as they intend, if you eat this snack food, there's these ready to heat meals as they intend, you're going to get diabetes and obesity. If scientists generally believe that, then you can't sell that. That's just against the law and the agency needs them to enforce the law. Bio:   Jerold Mande is CEO of Nourish Science; Adjunct Professor of Nutrition, Harvard T.H. Chan School of Public Health; and a Non-Resident Senior Fellow, Tisch College of Civic Life, Tufts University. Professor Mande has a wealth of expertise and experience in national public health and food policy. He served in senior policymaking positions for three presidents at USDA, FDA, and OSHA helping lead landmark public health initiatives. In 2009, he was appointed by President Obama as USDA Deputy Under Secretary for Food Safety. In 2011, he moved to USDA's Food, Nutrition, and Consumer Services, where he spent six years working to improve the health outcomes of the nation's $100 billion investment in 15 nutrition programs. During President Clinton's administration, Mr. Mande was Senior Advisor to the FDA commissioner where he helped shape national policy on nutrition, food safety, and tobacco. He also served on the White House staff as a health policy advisor and was Deputy Assistant Secretary for Occupational Health at the Department of Labor. During the George H.W. Bush administration he led the graphic design of the iconic Nutrition Facts label at FDA, for which he received the Presidential Design Award. Mr. Mande began his career as a legislative assistant for Al Gore in the U.S. House and Senate, managing Gore's health and environment agenda, and helping Gore write the nation's organ donation and transplantation laws.  Mande earned a Master of Public Health from the University of North Carolina at Chapel Hill and a Bachelor of Science in nutritional science from the University of Connecticut. Prior to his current academic appointments, he served on the faculty at the Tufts, Friedman School of Nutrition Science and Policy, and Yale School of Medicine.

Leslie Smith III (b. 1985) was born in Silver Spring, MD and lives and works in Madison, WI.  Smith's interests lie in our conscious effort to alter personal perception. Recent works explore Abstraction's inherent personal and political properties as they relate to broadening notions of Black representation and expression. Smith creates paintings with a mindset that it's possible to present a new interpretation of contemporary abstraction. One with expectations of a different sensibility than that offered by the 1950's and 60's, he offers an alternative worldview; one of inclusion and acceptance.  Leslie Smith III earned a BFA at the Maryland Institute College of Art and an MFA at the Yale School of Art. Smith exhibits nationally and internationally. His work can be found in the permanent collections of the High Museum of Art, Atlanta; the Virginia Museum of Fine Art, Richmond; the Birmingham Museum of Art; the Abroms-Engel Institute for the Visual Arts, Birmingham, AL; and the FRAC Auvergne, France. Leslie Smith III, Ancestral Meeting, 2025 Oil on shaped canvas and sewn upholstery fabric, 36 x 45 1/2 in 91.4 x 115.6 cm. Copyright The Artist Leslie Smith III,  Under the Skin of Light, 2025 Oil on shaped canvas 45 1/2 x 36 in 115.6 x 91.4 cm, Copyright The Artist Leslie Smith III, Night Scene From a Moving Train Window, 2025, Oil on shaped canvas and sewn upholstery fabric 36 x 45 1/2 in 91.4 x 115.6 cm. Copyright The Artist

James Kimmel, Jr., PhD, is an assistant clinical professor of psychiatry at the Yale School of Medicine and the author of The Science of Revenge. He’s known in part for identifying compulsive revenge seeking as an addiction. He explains how perceived wrongs, grievances, and revenge desires—and how we deal with them, or not—affect us all. Actually trying to get revenge is pretty much always a lost cause—it simply makes us feel worse—but often, blanket forgiveness feels impossible. Which is why Kimmel came up with a simple but brilliant process that you can run through in the courtroom of your mind. For the show notes, head to my Substack.See omnystudio.com/listener for privacy information.

Howie and Harlan discuss the outlook for U.S. healthcare spending over the next five years, the state of seasonal and avian flu, and an expensive AI-based cardiac test.  Show notes: Life expectancy and expenditures "How does U.S. life expectancy compare to other countries?" ACOs and cost savings "After Fifteen Years, is Value-Based Care Succeeding?" Health & Veritas Episode 115: Farzad Mostashari: Aligning Incentives to Fix Primary Care World Prematurity Day WHO: World Prematurity Day 2025 WHO: World Prematurity Day Key Messages WHO: Preterm birth AI concerns "'It keeps me awake at night': machine-learning pioneer on AI's threat to humanity" "Why neural net pioneer Geoffrey Hinton is sounding the alarm on AI" "AI pioneer: 'The dangers of abuse are very real'" "'Malicious use is already happening': machine-learning pioneer on making AI safer" "Fathers of the Deep Learning Revolution Receive ACM A.M. Turing Award" "Deep learning" Bird flu "First U.S. case of human bird flu in 9 months confirmed in Washington state" Cleveland Clinic: Bird Flu (Avian Influenza) "Flu in numbers: NHS faces one of worst winters ever, officials warn, amid concern over mutated strain" "New flu virus mutation could see 'worst season in a decade'" "Australia posts record-breaking flu numbers as vaccination rates stall"  FDA: Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season Cardiology and AI "Coronary CT angiography evaluation with artificial intelligence for individualized medical treatment of atherosclerosis: a Consensus Statement from the QCI Study Group" "Medicare will pay more than $1,000 for AI to analyze a heart scan. Is that too much?" Free speech and drug promotion "High-Engagement Social Media Posts Related to Prescription Drug Promotion for 3 Major Drug Classes" Health & Veritas Episode 195: Jerry Avorn: Countering the Drug Marketing Machine Medicare premiums "Medicare premiums to jump 10% heading into 2026" "Social Security Announces 2.8 Percent Benefit Increase for 2026" Centers for Medicare and Medicaid: 2026 Medicare Parts A & B Premiums and Deductibles In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings. Email Howie and Harlan comments or questions.

BUFFALO, NY — November 20, 2025 — A new #research paper was #published in Volume 17, Issue 10 of Aging-US on October 10, 2025, titled “Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not with the aneuploidy rate of the resulting blastocysts in good prognosis patients: a study of 25,974 embryos.” In this large-scale study, Andres Reig of the IVIRMA Global Research Alliance and Robert Wood Johnson Medical School, along with Emre Seli of the IVIRMA Global Research Alliance and Yale School of Medicine, investigated how female age and chromosomal abnormalities affect embryo development in patients undergoing in vitro fertilization (IVF). They found that embryo developmental arrest (EDA) becomes more common as women age. However, this arrest is not directly associated with the presence of chromosomal errors in the embryos that continue to develop. These findings could help improve fertility counseling and treatment strategies. The researchers analyzed 25,974 embryos from 1,928 IVF cycles, all from patients with a good chance of success. The study showed that the percentage of embryos that stopped developing before reaching the blastocyst stage increased with age: from 33% in women under 35 to 44% in those over 42. Despite this rise, the rate of chromosomal abnormalities, known as aneuploidy, in the embryos that did reach the blastocyst stage did not show a strong connection with the rate of arrest after adjusting for age. This distinction is important because both developmental arrest and aneuploidy reduce the number of embryos suitable for transfer. But this study suggests they are caused by different biological processes. In other words, an embryo may stop developing even if it has the correct number of chromosomes, and some embryos with chromosomal abnormalities may still grow to the blastocyst stage. “A very weak positive correlation was identified between EDA rate and the rate of aneuploidy (r: 0.07, 95% CI 0.03–0.11; R2: 0.00, p < 0.01) when evaluating all cohorts.” The authors suggest that other factors, such as the health of the egg's mitochondria or mutations in maternal-effect genes, may explain why some embryos stop developing. These insights could help researchers identify new ways to improve embryo quality, especially for older women undergoing IVF. Importantly, the study focused on embryos that developed far enough to be tested, which helped avoid technical problems that come with analyzing arrested embryos directly. This approach allowed for more reliable comparisons across age groups and embryo quality. Overall, the study highlights the importance of maternal age as a key factor in embryo development, independent of chromosomal results. It also opens new directions for research, aiming to better understand why embryos fail to develop and how this knowledge might lead to improved fertility treatments in the future. DOI - https://doi.org/10.18632/aging.206328 Corresponding author - Emre Seli - emre.seli@yale.edu Abstract video - https://www.youtube.com/watch?v=g0oS3HBNmuQ Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206328 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, ovarian aging, reproductive aging, embryonic arrest, embryonic aneuploidy, developmental arrest To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@Aging-US LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Today, on Notable Leaders' Radio, I speak with Jourdan Hathaway, Chief Business Officer of the General Assembly. She emphasizes how resilience, courage, and the willingness to ask for help have been key in her transition from a childhood of poverty to a successful executive leader.  In today's episode, we discuss: Reflect on the childhood influences that shaped you and your future aspirations. Jourdan shares how her experience growing up in extreme poverty shaped her early dream of working in advertising, inspired by the TV show "Bewitched." That dream became a guiding star through hardship. Create your own learning path to fill critical gaps. When promoted to a leadership role outside her area of expertise, Jourdan built Project FLAT: Financial Literacy Advancement Training to master finance through journaling, mentorship, and resilience quickly. Cultivate resilience as a core leadership skill. Jourdan's story illustrates how bouncing back from setbacks and persisting despite obstacles is essential for long-term success and impact. Define leadership through vulnerability and empathy. Jourdan explains how her acronym DRIVEN (determined, resilient, impactful, vulnerable, empathetic, nimble) reflects her belief that true leadership includes asking for help and lifting others up. RESOURCES: Guest Bio Jourdan Hathaway is Chief Business Officer at General Assembly, a global leader in talent development and upskilling. She oversees marketing, sales enablement, client delivery, admissions, student experience, career services, alumni relations, and partnerships. Jourdan's journey spans agency marketing to edtech, blending operational excellence with a passion for building inclusive, future-ready organizations. She is recognized for strategic leadership, business growth, and talent transformation, and serves as a mentor and member of the Exceptional Women Alliance.   Website/Social Links www.GA.co https://www.linkedin.com/in/jourdan-hathaway Belinda's Bio: Belinda is a sought-after Leadership Advisor, Coach, Consultant, and Keynote speaker and a leading authority in guiding global executives, professionals, and small business owners to become today's highly respected leaders. As the Founder of BelindaPruyne.com, Belinda works with organizations such as IBM, Booz Allen Hamilton, BBDO, The BAM Connection, Hilton, Leidos, Yale School of Medicine, Landis, Portland Trail Blazers, and the Discovery Channel. Most recently, she redesigned two global internal advertising agencies for Cella, a leader in creative staffing and consulting. She is a founding C-suite and executive management coach for Chief, the fastest-growing executive women's network. Since 2020, Belinda has conducted over 120 interviews with top-level executives and business leaders, who share their personal journeys to success, revealing the truth about what it took to achieve their success on her Notable Leaders Radio podcast. She gained a wealth of expertise in the client services industry as Executive Vice President and Global Director of Creative Management at Grey Advertising, managing over 500 people worldwide. With over 20+ years of leadership development experience, she brings industry-wide recognition to the executives and companies she works with. Whether a startup, turnaround, acquisition, or global corporation, executives and companies continue to turn to Pruyne for strategic and impactful solutions in a rapidly shifting economy and marketplace. Website: Belindapruyne.com Email Address: hello@belindapruyne.com LinkedIn: https://www.linkedin.com/in/belindapruyne  Facebook: https://www.facebook.com/NotableLeadersNetwork.BelindaPruyne/  Twitter: https://twitter.com/belindapruyne?lang=en  Instagram: https://www.instagram.com/belindapruyne/  Surround yourself with experienced mentors. From public speaking training to business skills, Jourdan emphasizes that growing into leadership is a journey supported by those who have already walked the path.  

This episode explores the stages of foundation responses to the Trump Administration's War on Charities, through the lens of a place-based funder network. Rusty sits down with Megan Thomas, CEO of Catalyst of San Diego and Imperial Counties. This regional funder association has worked with its members and local nonprofit advisors to build several rounds of collaborative funding, including cash flow assistance loans. You'll hear:The stages of local funder reaction and response to the Trump Administration's shock-and-awe tactics in their 2025 attacks on nonprofits and philanthropy;Why and how local funders began organizing with one another to create collective funding;How persistent leadership and courage can spur collective, partnership-based responses;The consequences of the Trump Administration's actions on the local social sectorMegan is a longstanding leader in the philanthropic community, and her organization, Catalyst, is one of Fund the People's partners in the California Talent Justice Initiative.This episode is part of our biweekly Defend Nonprofits, Defend Democracy Series, as well as our ongoing efforts to feature our California Talent Justice Initiative partners across the Golden State. Transcript:Edited PDF of Episode Transcript with Time StampsRelated episodes from FTP Podcast:Defend Nonprofits, Defend the Social Safety Net - with Edward Hershey, CEO, Home of Guiding Hands (San Diego)Nonprofit Staff Resilience and Wellbeing in Turbulent Times - with Loretta Turner, Founder and Strategist, Do Good Leadership CollectiveMacArthur President Chooses Courage, Not Quiet - with John Palfrey, President, MacArthur FoundationResources mentioned in the episode:Catalyst of San Diego and Imperial CountiesUSD Nonprofit Institute Report (March 2025)Coordinated Regional Response CollaborativeResilient Response FundSustained Support FundSan Diego Solidarity NetworkCommunity-Centric FundraisingGuest bio:Megan serves as Catalyst's president & CEO, providing strategic leadership and partnership to the entire Catalyst staff, board, members, and community partners. Megan oversees Catalyst's facilitation of collaborative efforts among its funder members and other stakeholders; leads the production of philanthropy and impact investing skills-building and issue based learning; and spearheads Catalyst's work related to championing equity and opportunity. She strengthens Imperial and San Diego County communities through shared learning and pooled and aligned funding strategies, and initiatives fiscally sponsored by Catalyst.Megan brings 20 years of experience in the nonprofit and philanthropic fields to this role, having most recently served as Executive Director of San Diego Coastkeeper where she built partnerships among the nonprofit, business, and public sectors to advance environmental goals across San Diego County. Megan received her Bachelor of Science in Business Administration from Georgetown University and her Masters in Business Administration from Yale School of Management. She serves on the board of directors for the United Philanthropy Forum (national) and the Museum of Us (San Diego).

Yale School of Public Health's Nathaniel Raymond: Sudan's Civil War Unleashed Worst Active Genocide and Famine in the World TodayUniversity of Wisconsin's former Associate Director of Middle East Studies Jennifer Loewenstein: The Dire Situation for Palestinians Living in Post-Ceasefire GazaSalon.com columnist Heather Digby Parton: Trump Drowning in Epstein File ScandalBob Nixon's Under-reported News Summary:• Venezuelans deported to CECOT tortured• U.S. sold sniper rifles to notorious Brazil police unit • DOGE conspiracy theories hampered Social Security servicesVisit our website at BTLonline.org for more information, in-depth interviews, related links, transcripts and subscribe to our BTL Weekly Summary and/or podcasts. New episodes every Wednesday at 12 noon ET, website updated Wednesdays after 4 p.m. ETProduced by Squeaky Wheel Productions: Scott Harris, Melinda Tuhus, Bob Nixon, Anna Manzo, Susan Bramhall, Jeff Yates and Mary Hunt. Theme music by Richard Hill and Mikata.

Yale School of Public Health's Nathaniel Raymond: Sudan's Civil War Unleashed Worst Active Genocide and Famine in the World TodayUniversity of Wisconsin's former Associate Director of Middle East Studies Jennifer Loewenstein: The Dire Situation for Palestinians Living in Post-Ceasefire GazaSalon.com columnist Heather Digby Parton: Trump Drowning in Epstein File ScandalBob Nixon's Under-reported News Summary:• Venezuelans deported by Trump to CECOT tortured• U.S. sold sniper rifles to notorious Brazil police unit • DOGE conspiracy theories hampered Social Security servicesVisit our website at BTLonline.org for more information, in-depth interviews, related links and transcripts and to sign up for our BTL Weekly Summary. New episodes every Wednesday at 12 noon ET, website updated Wednesdays after 4 p.m. ETProduced by Squeaky Wheel Productions: Scott Harris, Melinda Tuhus, Bob Nixon, Anna Manzo, Susan Bramhall, Jeff Yates and Mary Hunt. Theme music by Richard Hill and Mikata.

What do COVID-19 brain fog and ophthalmology have to do with Alzheimer's disease? There may be more connections than one might think. Dr. Sean Miller is one of the scientists behind a recent study that used retinal tissue to investigate the links between COVID-19 infections and the build-up of amyloid and other indicators of Alzheimer's disease in the central nervous system. Dr. Miller joins the podcast to discuss his research and its implications for COVID and dementia diagnosis and treatments in the future. Guest: Sean Miller, PhD, research scientist, department of ophthalmology and visual science, Yale School of Medicine, co-investigator, Logan Lab, Endicott College  Show Notes Read Dr. Miller's study, “SARS-CoV-2 induces Alzheimer's disease–related amyloid-β pathology in ex vivo human retinal explants and retinal organoids,” on the journal Science's website. Learn more about Dr. Miller at his profile on the Yale School of Medicine website. Read “Retinal pathological features and proteome signatures of Alzheimer's disease,” mentioned by Dr. Miller at 2:50, on the National Library of Medicine website. Listen to our past episode, “Long COVID and Its Effect on Cognition,” on our website for more information on how COVID-19 can affect the brain. Connect with us Find transcripts and more at our website. Email Dementia Matters: dementiamatters@medicine.wisc.edu Follow us on Facebook and Twitter. Subscribe to the Wisconsin Alzheimer's Disease Research Center's e-newsletter. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer's. All donations go toward outreach and production.

Recorded November 10, 2025 - The Korea Society is pleased to announce that the ninth annual Sherman Family Korea Emerging Scholar Lecture Awardee is Dr. Peter Jongho Na, assistant professor of psychiatry at Yale School of Medicine.  In his lecture, Reframing Suicide as a Shared Social Responsibility in Korea, he casts suicide not as an individual failure or "extreme choice (극단적 선택)," but as a systemic and cultural crisis requiring a coordinated national response. Drawing on his experience as a psychiatrist, public health researcher, and mental health advocate, he examines the scale and societal costs of suicide in Korea and analyzes key structural drivers such as academic and workplace pressures, poverty and isolation among older adults, and the pervasive stigma surrounding mental illness and treatment.  A central theme is how stigma has sustained silence, denial, and policy inertia. Dr. Peter Jongho Na shares his efforts to challenge euphemistic language and foster open public dialogue, while proposing an interdisciplinary roadmap inspired by global models that integrate public health, education, and social welfare reforms. Further, he highlights the Korean diaspora's potential role in breaking taboos and advancing cultural and policy change, underscoring that suicide prevention must be embraced as a collective, societal responsibility. Note: This presentation includes discussion of suicide and mental health topics that may be distressing to some individuals. For more information, please visit the link below: https://www.koreasociety.org/korean-studies/2069-sherman-family-korea-emerging-scholar-lecture-2025

It's been a huge few weeks for climate news. Democrats swept state and local elections in New Jersey, Virginia, California, and New York City — and won two crucial regulatory races in Georgia. A few weeks before, the climate tech investor and philanthropist Bill Gates released a memo arguing for a pivot on climate funding vis a vis global health.On this special episode of Shift Key, Rob talks to Heatmap staff writers Emily Pontecorvo and Matthew Zeitlin about what the 2025 elections might mean for climate policy, why “affordability” politics could hamper decarbonization, and whether the Gates memo represents anything but a rebrand. They recorded this conversation live at the Yale School of Management's annual clean energy conference in New Haven, Connecticut.Shift Key is hosted by Robinson Meyer, the founding executive editor of Heatmap, and Jesse Jenkins, a professor of energy systems engineering at Princeton University. Jesse is off this week.Mentioned: How Mikie Sherrill Won New Jersey's Electricity Election, by Matthew Democrats Win 2 Key Energy Races in Georgia, by EmilyZohran Mamdani's Muted Climate Politics, by Rob7 New Takes From Bill Gates on Climate ‘Doomsday' Talk and Global HealthWhere Bill Gates Got It Wrong, by Zeke HaufatherPreviously on Shift Key: How to Talk to Your Friendly Neighborhood Public Utility Regulator--This episode of Shift Key is sponsored by …Hydrostor is building the future of energy with Advanced Compressed Air Energy Storage. Delivering clean, reliable power with 500-megawatt facilities sited on 100 acres, Hydrostor's energy storage projects are transforming the grid and creating thousands of American jobs. Learn more at hydrostor.ca.Uplight is a clean energy technology company that helps energy providers unlock grid capacity by activating energy customers and their connected devices to generate, shift, and save energy. The Uplight Demand Stack — which integrates energy efficiency, electrification, rates, and flexibility programs — improves grid resilience, reduces costs, and accelerates decarbonization for energy providers and their customers. Learn more at uplight.com/heatmap.Music for Shift Key is by Adam Kromelow. Hosted on Acast. See acast.com/privacy for more information.

On this replay preview of Brave New World, Evgeny Lebedev is joined by Dr John Krystal — Professor of Neuroscience at the Yale School of Medicine — to explore how ketamine could transform the treatment of mental health disorders.They discuss what ketamine is, how it works, and why it's being hailed as a breakthrough in tackling the global mental health crisis.Listen to the full conversation on the Brave New World podcast here. Hosted on Acast. See acast.com/privacy for more information.

"It is my life that I claim. That sense of empowerment wouldn't have happened without the Process." Ana Bok Today's conversation with Hoffman graduate Ana Bok begins with Ana sharing a story that happened three years after her Process. Her week at Hoffman provided a powerful foundation that would come to help guide her through a tough time. Since childhood, Ana's dream has been to become a doctor. At age fourteen, she came to the United States. After graduating with her undergraduate degree in  Neuroscience with a concentration in Behavioral Studies, Ana planned to attend Yale Medical School. But first, she was a post-graduate research associate at a child psychiatry research lab at the Yale Child Study Center. She was on her way to her long-held dream. But there, Ana found herself in inner turmoil and conflict. Already a Hoffman grad, Ana had thought to herself that after the Process, she was on her "right road" and that everything was "supposed to work." She didn't know what was wrong, but she knew her Quadrinity was out of alignment. Listen in to hear Ana tell about this pivotal moment along the journey of her life. The Process offers a powerful foundation for navigating life. Ana found hope at the Process. Hope and her Spiritual Self guided Ana through this difficult time. Ana's story is powerful because it reminds us that after doing the Process, life is still life. How life works hasn't changed, but we have. We hope you enjoy this deeply vulnerable and moving conversation with Ana and Drew. More about Ana Bok: Ana was born in Korea, raised in China, and moved to the U.S. alone at age fourteen. She studied Neuroscience with a concentration in Behavioral Studies at Columbia University and spent five years researching molecular pathobiology and pain mechanisms during and after college. In 2022, Ana attended the Hoffman Process, which affirmed her deep interest in child and adolescent mental health.  Ana recently completed two years of postgraduate training at the Yale Child Study Center. She continues her research on obsessive-compulsive disorder at the Yale School of Medicine. Fascinated by the intersection of science and spirituality, Ana hopes to one day integrate spirituality into early mental health interventions. Alongside her research, Ana has mentored middle and high school students, supporting their academic and personal growth. Ana served as a NYC Hoffman Graduate Group Leader in 2022–2023 before her fellowship at Yale and recently returned as a co-facilitator for the NYC Uptown Hoffman group. She welcomes connections from fellow Hoffman graduates and can be reached at dianabok.connect@gmail.com. Listen on Apple Podcasts Listen on Spotify As mentioned in this episode: Left Road/Right Road: The left road represents repeating patterns from your past, while the right road is the path of authenticity, choice, and self-responsibility. The Quadrinity™ Symbol Bob Hoffman designed the Hoffman Quadrinity™ Symbol in 1967 to represent the wholeness of Self. The circle represents the Body; the large vertical diamond in the middle represents the Spirit; the 2 smaller horizontal diamond shapes represent the Intellect and Emotions. The whole is greater than the sum of its parts.   Korean fortune-telling: "Saju" is a traditional Korean fortune-telling system that analyzes an individual's birth year, month, day, and hour to create a personal profile. It is a widely practiced cultural tradition for seeking guidance on personality, relationships, career, and life path. It is often used for entertainment as well as for serious life decisions. Rooted in ancient Chinese metaphysics, saju calculates cosmic energy at the time of birth to provide insights into one's destiny.   

Today, I am delighted to speak with Dr. Paul Hokemeyer, founding principal of Drayson Mews and author of Fragile Power: Why Having Everything is Never Enough and Fragile Power 2.0: Wealth, Narcissism & Mental Health, the leading resources for individuals, couples, and families of wealth seeking culturally respectful and clinically effective mental health services. Dr. Paul serves as the Senior Wellness Expert to Ispahani Advisory, a London-based consulting firm specializing in multijurisdictional, ultra-high-net-worth families. He is an Associate Member of the American Association for Addiction Medicine and holds a Clinical Fellow designation with the American Association for Marriage and Family Therapy. In addition to his academic and clinical work, Dr. Paul has extensive experience in the realm of philanthropy. He has stewarded over three million U.S. dollars to enhance the delivery of direct mental health services to disenfranchised communities across America, as well as through the Yale School of Public Health, and he serves as a trustee of the Palm Springs Art Museum, one of the world's premier centers for mid-century art, architecture, and design. Dr. Paul's research in the realm of wealth and mental health has been peer-reviewed and published in the Journal of Wealth Management, the International Family Offices Journal, Globe Law and Business, and Lambert Academic Press. His work has been featured in a wide variety of international media outlets including The New York Times, The Wall Street Journal, The World Economic Forum, the Johns Hopkins Newsletter, Harvard Business Review Arabia, CNN, Men's Health, The Guardian, Tatler, WebMD, Psych Central and others. Dr. Paul starts by explaining what intersectionality is. He tells us about the origins of the construct of intersectionality and highlights some of the key premises underlying the term and the studies behind it. He then describes how intersectionality plays in the UHNW and family office space, and how it manifests itself in the lives and wellbeing of UHNW clients. Dr. Paul offers his practical tips for wealth owners, family wealth principals, and UHNW family members? He offers his advice on what they should know about intersectionality and how they should incorporate this knowledge into their lives and their relationship with wealth. He also provides practical suggestions for family wealth advisors and how they should integrate this concept into their advisory practice and utilize it to strengthen their relationships with their UHNW clients. Enjoy this illuminating conversation with one of the leading academics and practitioners at the complex intersection wealth management and personal health and wellness.

Howie and Harlan are joined by Harvard internist Jerry Avorn to discuss his research on the pharmaceutical industry and his work promoting evidence-based prescribing. Harlan highlights new results from the American Heart Association meeting, including a one-time CRISPR-based therapy for high cholesterol; Howie reports on an outbreak of infant botulism. Show notes: Research from the American Heart Association Meeting "Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3" "First-in-human trial of CRISPR gene-editing therapy safely lowered cholesterol, triglycerides" "Cardiac Allograft Vasculopathy Inhibition with Alirocumab: The CAVIAR Trial" "PCSK9 medication plus statin may help lower cholesterol after heart transplant" "Investigational daily pill lowered bad cholesterol as much as injectables" Jerry Avorn Science Direct: Academic Detailing Jerry Avorn: "Principles of Educational Outreach ('Academic Detailing') to Improve Clinical Decision Making" Alosa Health FDA: Accelerated Approval Jerry Avorn: Rethinking Medications: Truth, Power, and the Drugs You Take FDA: Direct-to-Consumer (DTC) Advertisements H.R.5952 - Prescription Drug User Fee Act of 1992 FDA: FY 2025 FDA Budget Summary Centers for Medicare & Medicaid Services: Open Payments  H.R.3590 - Patient Protection and Affordable Care Act "Aducanumab Discontinued as an Alzheimer's Treatment" FDA: ELEVIDYS Brigham and Women's Hospital & Harvard Medical School: Division of Pharmacoepidemiology and Pharmacoeconomics Amazon.com: Featured comments on Rethinking Medications Infant Botulism California Department of Public Health: "Outbreak of Infant Botulism Linked to ByHeart Infant Formula" California Department of Public Health: Infant Botulism Treatment and Prevention Program CDC: "Infant Botulism Outbreak Linked to Infant Formula, November 2025" "ByHeart recalls all baby formula sold nationwide as infant botulism outbreak grows" California Department of Public Health: What is BabyBIG? California Department of Public Health: Postponement of BabyBIG Fee Increase California Department Of Public Health: Invoice and Purchase Agreement for BabyBIG In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings. Email Howie and Harlan comments or questions.  

Today, on Notable Leaders' Radio, I speak with Tony Crescenzo, CEO of Intelligent Waves & Founder of Peak Neuro, LLC. He highlights his compelling journey from a resilient upbringing and military service to pioneering leadership insights and transformative healing with brain-training technology.   In today's episode, we discuss: Remember the importance of "always do the right thing." Tony's grandfather's timeless advice served as his moral compass, guiding him through every personal and business decision. He discovered that by valuing integrity, you foster trust and build a strong, lasting reputation. See adversity as an opportunity to grow and learn. Tony's time in the military, especially the hurdles he faced as his military career came to a close, reminds us how much reputation truly matters. Welcome setbacks as moments to build character and become someone others truly respect and trust. To ease conflicts, try to understand the root of fear rather than just anger. Through his journey with anger, he learned that anger is really fear turned upside down. Embracing this awareness enabled him to transition from fear/anger to compassion and a deeper understanding of himself and others in times of challenge. Consider responding to anger with empathy—it can be a beautiful way to strengthen both your work and personal relationships. Prioritize your sleep and mental health with effective strategies. For instance, Tony saw wonderful improvements in his sleep, memory, and mood by using brainwave entrainment. Taking some proactive steps to care for yourself—such as getting good rest and keeping your mind clear—can truly make a significant difference in your happiness and productivity. Adopt the idea of "generals eat last" as your leadership guiding principle. As Tony beautifully shared, inspiring leaders always put their teams first, creating a warm environment full of trust and stability. When you focus on serving and supporting others, it gently builds loyalty and can significantly lift your team's performance. Embracing this approach can truly make your leadership journey more rewarding and fulfilling! Be open to new modalities of healing. Tony lived with PTSD for 30 years. He believed his anger and stress from his time in the military were a part of him and his life now. It wasn't until he stumbled across a new assistive technology that he learned that was not the case. It is also inspired the creation of PeakNeuro, an AI-enabled platform that uses acoustic audio-entrainment to help veterans and leaders regulate stress, get better sleep, and improve human performance overall through cognitive resilience. Is anger and or stress driving your life? If yes, check out PeakNeuro. It may be just the help you have been looking for. RESOURCES: Complementary Resources: Enclosed Link to a published article about the science of PeakNeuro: https://info.peakneuro.com/documents/2025JUN24PCSRwithTrainingSummary.pdf  Guest Bio Tony Crescenzo is the President and Chief Executive Officer of Intelligent Waves (IW), a veteran-owned, mission-driven systems integrator delivering advanced technology solutions in cybersecurity, systems engineering, data science, software development, and cognitive human performance to the U.S. government. Simultaneously, he is the Founder of Peak Neuro, LLC, a neuroscience and AI-powered company. Peak Neuro harnesses proprietary neuroacoustic technology through a mobile app to enhance sleep, emotional resilience, and trauma recovery—especially for veterans and first responders suffering from PTSD, TBI, or chronic stress. Website/Social Links LinkedIn Social Media:  https://www.linkedin.com/in/tonycrescenzo/   Intelligent Waves' website: https:/www.IntelligentWaves.com  Peak Neuro, LLC: https://www.PeakNeuro.com  BOOKS UnSEALed: A Navy SEAL's Guide to Mastering Life's Transitions by Mark Greene & Sheilby Rawson https://amzn.to/47qDR5P Belinda's Bio: Belinda is a sought-after Leadership Advisor, Coach, Consultant and Keynote speaker and a leading authority in guiding global executives, professionals and small business owners to become today's highly respected leaders. As the Founder of BelindaPruyne.com, Belinda works with such organizations as IBM, Booz Allen Hamilton, BBDO, The BAM Connection, Hilton, Leidos, Yale School of Medicine, Landis, and the Discovery Channel. Most recently, she redesigned two global internal advertising agencies for Cella, a leader in creative staffing and consulting. She is a founding C-suite and executive management coach for Chief, the fastest-growing executive women's network. Since 2020, Belinda has delivered more than 72 interviews with top-level executives and business leaders who share their inner journey to success; letting you know the truth of what it took to achieve their success in her Notable Leaders Radio podcast. She gained a wealth of expertise in the client services industry as Executive Vice President, Global Director of Creative Management at Grey Advertising, managing 500 people around the globe. With over 20+ years of leadership development experience, she brings industry-wide recognition to the executives and companies she works with. Whether a startup, turnaround, acquisition, or global corporation, executives and companies continue to turn to Pruyne for strategic and impactful solutions in a rapidly shifting economy and marketplace. Website: Belindapruyne.com Email Address: hello@belindapruyne.com LinkedIn: https://www.linkedin.com/in/belindapruyne  Facebook: https://www.facebook.com/NotableLeadersNetwork.BelindaPruyne/  Twitter: https://twitter.com/belindapruyne?lang=en  Instagram: https://www.instagram.com/belindapruyne/ 

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses the link between in utero SARS-CoV-2 infection and poor neurodevelopment outcomes, the use of an mRNA vaccine as an anti-cancer therapy, why one should receive the HPV vaccine, asymptomatic H5N1 isolations in humans, and H5N1 on turkey farms, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how two vaccinated physicians became infected with measles, effective of COVID-19 vaccine for children, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how a specific antibody type may associate with recovery from long COVID, if use of a probiotic is helpful to treat mild COVID-19, if vaccination helps prevent long in adolescents and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero (Obstetrics & Gynecology) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1267: A cancer vaccine and an mpox treatment (microbeTV: TWiV1267) Cancers Caused by HPV (CDC: Human papillomavirus (HPV)) Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of National Cancer Institute) Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine (Viruses) ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP)) HPV Vaccination Recommendation (CDC: Vaccines & Immunizations) Asymptomatic Human Infections With Avian Influenza A(H5N1) Virus Confirmed by Molecular and Serologic Testing (JAMA: OPEN Network) Review: Human H5N1 avian flu cases can be asymptomatic, and the virus likely spreads among people (CIDRAP) Avian flu strikes turkey farms in Dakotas, large egg facility in California (CIDRAP) Another Doctor at Ichilov Contracts Measles After Treating Unvaccinated Child (gov.il) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England (LANCET: Child & Adolescent Health) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Real-World Effectiveness of Nirmatrelvir-Ritonavir in Preventing Coronavirus Disease 2019–Associated Hospitalization (CID) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID SARS-CoV-2 spike-specific IgG4 class switching associates with clinical recovery in Long COVID (Journal of Infection) Efficacy of Lactococcus lactis Strain Plasma in Patients with Mild COVID-19 (Infectious Diseases and Therapy) Preventive effect of vaccination on long COVID in adolescents with SARS-CoV-2 infection (Vaccine) Reaching out to US house representative Letters read on TWiV 1268 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Howie and Harlan are joined by cardiologist Ali Rahimi, the founder of ALYKA Health, which uses a personalized mobile app to help patients manage their heart health between doctor's visits. Harlan discusses new developments in GLP-1 obesity drugs, including untested microdose treatments; Howie reviews a landmark study investigating whether broad prostate cancer screening saves lives. Show notes: GLP-1 Drugs "Microdosing aims to extend the lifespan of the GLP-1 compounding market" NIH: Regulatory Framework for Compounded Preparations Health & Veritas Episode 140: Lee Schwamm: Smarter Healthcare Systems With AI "FDA takes on GLP-1 compounding boom with warnings about misleading marketing" "Should You Microdose GLP-1 Drugs?" "How microdosing GLP-1 drugs became a longevity 'craze'" "Bidding war between Pfizer, Novo Nordisk for obesity startup Metsera escalates" "Trump Negotiating Deal With Ozempic Maker to Sell Some Weight-Loss Drugs for $149""Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment" "How Ozempic's Maker Lost Its Shine After Creating a Wonder Drug" Ali Rahimi ALYKA Health Harlan Krumholz and Ali Rahimi, "Financial Barriers to Health Care and Outcomes After Acute Myocardial Infarction" "Why High Blood Pressure Matters to Your Health" Building a Better Delivery System: A New Engineering/Health Care Partnership NIH: The 21st Century Cures Act New Evidence on Prostate Cancer Screening and Breast Cancer Treatment National Cancer Institute: Cancer Stat Facts: Prostate Cancer" U.S. Preventive Services Task Force: Prostate Cancer: Screening" "The pros and cons of PSA tests for prostate cancer for midlife and older men" "Share on European Study of Prostate Cancer Screening — 23-Year Follow-up" "Early Detection of Prostate Cancer — Time to Fish or Cut Bait" "Ten-Year Survival after Postmastectomy Chest-Wall Irradiation in Breast Cancer" "Omission of Chest-Wall Irradiation after Mastectomy for Breast Cancer" In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings. Email Howie and Harlan comments or questions.  

Revenge is as old as humanity itself. And new research shows that revenge functions in our brains like a type of addiction. This hour a look at revenge in politics, literature, and everyday life — and what it would mean if we treated revenge differently. GUESTS: James Kimmel Jr.: Lawyer, author, Assistant Clinical Professor of Psychiatry at the Yale School of Medicine, and the Founder and Co-Director of the Yale Collaborative for Motive Control Studies. His new book is The Science of Revenge: Understanding the World's Deadliest Addiction--and How to Overcome It Emily King: Visiting Assistant Professor of Writing and English at Washington and Lee University. She is author of Civil Vengeance: Literature, Culture, and Early Modern Revenge MUSIC FEATURED (in order): Il Trovatore: Anvil Chorus – Giuseppe Verdi, Budapest Festival Orchestra & Chorus The Payback – James Brown The Mariner’s Revenge Song – The Decemberists These Boots Are Made for Walkin’ – Nancy Sinatra Smile – Lily Allen no body, no crime - Taylor Swift Support the show: http://www.wnpr.org/donateSee omnystudio.com/listener for privacy information.

James Magruder is an American playwright, author, and translator. Magruder received his doctorate in dramaturgy and dramatic criticism at the Yale School of Drama. He is best known for his work on Broadway where he wrote the book for the musical Triumph of Love and adapted Jeff Whitty's original book for the Broadway mounting of the musical Head over Heels. Click here to learn more. Spies, Lies and Private Eyes is copyrighted by Authors on the Air Global Radio Network #authorsofinstagram #authorinterview #writingcommunity #authorsontheair #suspensebooks #authorssupportingauthors #thrillerbooks #suspense #wip #writers#writersinspiration #books #bookrecommendations #bookaddict #bookaddicted #bookaddiction #bibliophile #read #amreading #lovetoread #terrencemccauley #terrencemccauleybooks #bookouture #thrillers #TheTwilightTown #JamesMagruder #NoOneIsLookingAtYou

For over 25 years, Tyson Ray has sat in the same seat many entrepreneurs find themselves in today: running a successful business, serving clients at the highest level, and facing the question of what comes next.As co-founder and CEO of FORM Wealth Advisors, Tyson has led through market cycles, built a multigenerational team, acquired firms, and guided clients through every kind of transition. He spent years focused on everyone else's future until he realized his own succession plan wasn't where it needed to be.That moment became the foundation for the SPACE Framework™ (See, Prepare, Act, Commit, Exit), which Tyson shares in his latest book Total Succession. Built for advisors who care deeply about their clients, their teams, and the legacy they leave behind, it offers a clear path to exit with confidence and full compensation.Tyson holds advanced credentials from the Yale School of Management and the Business Enterprise Institute, along with his CFP®, CIMA®, and CExP® designations. His work has earned national recognition, including:• Barron's Top 1,200 Advisors (2021–2024)• Forbes Best-in-State Wealth Advisor (2018–2024)• AdvisorHub Top 150 Advisors to Watch Under $1B (2024)• Chairman's Council Advisor (2005–2024)Beyond the business, Tyson is co-founder of Children's World Impact, a nonprofit providing global humanitarian aid. His leadership there has been recognized with the Invest in Others Global Community Impact Award and REP. Magazine's Advisor with a Heart.Learn more: http://totalsuccession.com/Influential Entrepreneurs with Mike Saundershttps://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/Source: https://businessinnovatorsradio.com/interview-with-tyson-ray-co-founder-and-ceo-of-form-wealth-advisors

For over 25 years, Tyson Ray has sat in the same seat many entrepreneurs find themselves in today: running a successful business, serving clients at the highest level, and facing the question of what comes next.As co-founder and CEO of FORM Wealth Advisors, Tyson has led through market cycles, built a multigenerational team, acquired firms, and guided clients through every kind of transition. He spent years focused on everyone else's future until he realized his own succession plan wasn't where it needed to be.That moment became the foundation for the SPACE Framework™ (See, Prepare, Act, Commit, Exit), which Tyson shares in his latest book Total Succession. Built for advisors who care deeply about their clients, their teams, and the legacy they leave behind, it offers a clear path to exit with confidence and full compensation.Tyson holds advanced credentials from the Yale School of Management and the Business Enterprise Institute, along with his CFP®, CIMA®, and CExP® designations. His work has earned national recognition, including:• Barron's Top 1,200 Advisors (2021–2024)• Forbes Best-in-State Wealth Advisor (2018–2024)• AdvisorHub Top 150 Advisors to Watch Under $1B (2024)• Chairman's Council Advisor (2005–2024)Beyond the business, Tyson is co-founder of Children's World Impact, a nonprofit providing global humanitarian aid. His leadership there has been recognized with the Invest in Others Global Community Impact Award and REP. Magazine's Advisor with a Heart.Learn more: http://totalsuccession.com/Influential Entrepreneurs with Mike Saundershttps://businessinnovatorsradio.com/influential-entrepreneurs-with-mike-saunders/Source: https://businessinnovatorsradio.com/interview-with-tyson-ray-co-founder-and-ceo-of-form-wealth-advisors

10/31/25: Dr. Megan Ranney is an emergency physician, researcher, and advocate for innovative approaches to public health. She is the Dean of the Yale School of Public Health and a Professor of Emergency Medicine at Yale University. (Joel Heitkamp is a talk show host on the Mighty 790 KFGO in Fargo-Moorhead. His award-winning program, “News & Views,” can be heard weekdays from 8 – 11 a.m. Follow Joel on X/Twitter @JoelKFGO.)See omnystudio.com/listener for privacy information.

Howie and Harlan are joined by Nate Wood, a Yale School of Medicine internist and trained chef, to discuss his work combining lifestyle guidance with hands-on training in making healthy, tasty food. Harlan shares new guidance on what counts as a healthy blood pressure; Howie provides an update on rising health insurance costs. Links: Blood Pressure Harlan Kumholz, "Severe Hypertension: The Next Never Event" JACC: 2025 High Blood Pressure Guidelines Resources "Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension" Obesity Drugs "Semaglutide and Tirzepatide for Obesity: Effectiveness and Value" "Institute for Clinical and Economic Review Publishes Evidence Report on Treatments for Obesity" Harlan Krumholz and Jason Abaluck, "Changes in Cardiovascular Risk Factors and Health Care Expenditures Among Patients Prescribed Semaglutide" Culinary Medicine "Culinary Medicine: The Secret Ingredient to Good Health" American College of Lifestyle Medicine "How each lifestyle medicine pillar supports good nutrition" Dr. John La Puma "What to know about 'hyperpalatable' foods" Food is Medicine Coalition: Our Model American Academy of Family Physicians: Shared Medical Appointments/Group Visits Cleveland Clinic: GLP-1 Agonists Yale New Haven Hospital: Irving and Alice Brown Teaching Kitchen "Bringing Culinary Medicine to Yale's New Teaching Kitchen" Dr. Nate Wood Nate Wood on Instagram Health Insurance Costs Kaiser Family Foundation: 2025 Employer Health Benefits Survey "Health Benefits In 2025: Family Premiums Rise 6 Percent, Large Employers Increase Coverage Of GLP-1s For Weight Loss" "Annual Family Premiums for Employer Coverage Rise 6% in 2025, Nearing $27,000, with Workers Paying $6,850 Toward Premiums Out of Their Paychecks" "8 Things to Watch for the 2026 ACA Open Enrollment Period" "ACA Insurers Are Raising Premiums by an Estimated 26%, but Most Enrollees Could See Sharper Increases in What They Pay" Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Spotify, Oracle, and Comcast have each recently announced they're going with co-C.E.O.s. In this 2023 episode, we dig into the research and hear firsthand stories of triumph and disaster. Also: lessons from computer programmers, Simon and Garfunkel, and bears versus alligators.   SOURCES:Jim Balsillie, retired chairman and co-C.E.O. of Research In Motion.Mike Cannon-Brookes, co-founder and C.E.O. of Atlassian.Scott Farquhar, co-founder and former co-C.E.O. of Atlassian.Marc Feigen, C.E.O. advisor.Jeffrey Sonnenfeld, professor of management studies and senior associate dean at the Yale School of Management and founding president of the Chief Executive Leadership Institute.Laurie Williams, professor of computer science at North Carolina State University. RESOURCES:"Scott Farquhar to resign as joint CEO of Atlassian," by Jonathan Barrett (The Guardian, 2024)."Is It Time to Consider Co-C.E.O.s?" by Marc A. Feigen, Michael Jenkins, and Anton Warendh (Harvard Business Review, 2022)."The Costs and Benefits of Pair Programming," by Alistair Cockburn and Laurie Williams (2000)."Strengthening the Case for Pair Programming," by Laurie Williams, Robert R. Kessler, Ward Cunningham, and Ron Jeffries (IEEE Software, 2000). EXTRAS:"The Secret Life of a C.E.O.," series by Freakonomics Radio (2018). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Groin bulges, scrotal swelling, and nonpalpable testes are findings that often surface during routine well-child exams, and they can raise immediate questions for pediatricians and families alike. Is this normal? Will it resolve on its own? Or does it require surgical referral? In this episode, we take a closer look at three common genitourinary conditions in children: inguinal hernias, hydroceles, and undescended testes. We diagnose the details to help clarify the evaluation process, management strategies, and referral guidelines that every pediatrician should know.  This episode was recorded on the exhibit floor at the 2025 American Academy of Pediatrics Conference in Denver, Colorado. Joining us is Eric Bortnick, MD. He is a Urologist and Assistant Professor of Urology at the Yale School of Medicine.   Some highlights from this episode include:  How common these conditions are in the pediatric population  When pediatricians can make a difference in these patients lives, versus when referral is really necessary.  Key takeaways to performing a successful physical exam  Creating a safe space for proper diagnosis  For more information on Children's Colorado, visit: childrenscolorado.org. 

Most people don't realize that what happens in the mouth can ripple through the whole body. The balance of the oral microbiome—the community of bacteria living in our mouths—can either protect us or trigger widespread inflammation that affects the heart, joints, and brain. Hidden dental infections or mercury fillings can quietly drive fatigue, autoimmune issues, or dementia—and fixing the mouth often helps the rest of the body heal, too. The good news is that with simple steps like eating whole foods (often removing gluten), cleaning the mouth well, and breathing through the nose, we can protect both our smile and our overall health. When we care for the mouth as part of the body, lasting wellness becomes possible from the inside out. In this episode, Dr. Todd LePine, Dr. Elizabeth Boham, James Nestor, and I talk about how a healthy mouth microbiome is a key to whole-body wellness. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine's focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women's Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. James Nestor is an author and journalist who has written for Scientific American, Outside, The New York Times, and more. His book, Breath: The New Science of a Lost Art, was an instant New York Times and London Sunday Times bestseller. Breath explores how the human species has lost the ability to breathe properly—and how to get it back. Breath spent 18 weeks on the New York Times bestseller list in the first year of release, and will be translated into more than 30 languages. Breath was awarded the Best General Nonfiction Book of 2020 by the American Society of Journalists and Authors, and was nominated for Best Science Book of 2021 by the Royal Society. Nestor has spoken at Stanford Medical School, Yale School of Medicine, Harvard Medical School, The United Nations, Global Classroom, and appeared on more than 60 radio and television shows, including Fresh Air with Terry Gross, the Joe Rogan Show, and more. He lives and breathes in San Francisco. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here:The Functional Medicine Approach To Oral Health Getting Rid of Cold Sores and Canker Sores The Power Of Breath As Medicine

What changes when people are able to bring their deepest values to work? What are the critical responsibilities businesses must uphold for society in today's times? How can organizations gain the cultural confidence to do what's right, even when the odds are against them? And what does it take for ordinary individuals to build a business that puts purpose before profit and become a role model for the entire business community?Find out from Vincent Stanley, exclusively in conversation with Dr. Hitendra Wadhwa on Intersections Podcast.Vincent Stanley has been with Patagonia on and off since its beginning in 1973, and has served in key executive roles as head of sales or marketing. At present, he serves as Director of Patagonia Philosophy, teaching company history and values to employees. More informally, he is Patagonia's long-time chief storyteller. Vincent helped develop The Footprint Chronicles, the company's interactive website that outlines the social and environmental impact of its products, The Common Threads Partnership, an initiative launched by Patagonia in collaboration with eBay, aiming to reduce environmental impact by promoting sustainable consumption habits; and Patagonia Books, the publishing branch of Patagonia, that produces high‑quality books aligned with the brand's mission of environmental stewardship, adventure, and activism. He has co-authored two books with Yvon Chouinard, the founder of Patagonia: The Responsible Company (2012) and The Future of the Responsible Company (2023). Vincent is also a visiting fellow at the Yale School of Management, and also a poet whose work has appeared in Best American Poetry, a prominent annual anthology that showcases a curated selection of contemporary American poems.In this episode, Vincent reveals:- What changes when people are able to bring their deepest values to work- The minimum responsibility businesses must uphold in today's times- What shifts when we see responsibility as a right, not a burden

How will you age? Whether you are in your late twenties, fifties, or late eighties, everyone feels they are getting older. Of course we are chronologically getting older, so is a child, but we view children as growing older and better. Earlier and earlier these days however we view every day getting older as a negative and we expect to be less capable. Should this be the case? And how is the negative view of aging hurting us all, no matter what age you are as you hear this. This is a big topic of interest for me. I'm 54 and feel as capable as ever, and want to maintain this as long as possible. So I brought on an expert. Dr. Becca Levy, Ph.D., is an award-winning professor of Epidemiology (Social and Behavioral Sciences) at Yale School of Public Health and Professor of Psychology at Yale University. She has given invited testimony before the United States Senate on the effects of ageism, contributed to briefs submitted to the United States Supreme Court in age-discrimination cases, and participated in United Nations discussions of ageism. She is credited with creating a field of study that focuses on how positive and negative age stereotypes affect the health of older individuals. She is the author of Breaking the Age Code: How Your Beliefs About Aging Determine How Long & Well You Love. Sign up for your $1/month trial period at shopify.com/kevin Go to shipstation.com and use code KEVIN to start your free trial. Learn more about your ad choices. Visit megaphone.fm/adchoices

Today, on Notable Leaders' Radio, I speak with Kash Rocheleau, CEO of Icon Foods, Inc.. She discusses the importance of mentorship, fostering cultures of ownership and transparency, and explains why real growth occurs when we step outside our comfort zones. In today's episode, we discuss: Recognize the impact of supportive mentors in your life. Seek out people who champion your goals and remind you of your strengths during challenges; even one person who believes in you can turn obstacles into opportunities.  Lean into self-reliance but also understand when collaboration is important. Balancing independence with the ability to ask for help allows you to own your journey while benefiting from collective wisdom, a dynamic that improves both personal and professional relationships.  Embrace your imperfections as valuable leadership assets. When you let go of perfectionism and openly admit your mistakes, it demonstrates authenticity that naturally builds trust and boosts team morale. Remember, vulnerability can often be your greatest strength.  Foster cultures of ownership and transparency wherever you are. Whether as a leader or team member, contributing to an environment where people feel responsible for outcomes creates a sense of pride and belonging that benefits everyone. Reexamine the personal “ceilings” you accept or create in your life. Believe that your potential is not capped by others but by yourself, and seek (or become) the kind of support that encourages ambition, so you always have the permission to grow. RESOURCES: Guest Bio: Kash Rocheleau is the CEO of Icon Foods, a leading supplier of clean-label sweetening systems and functional ingredients for the food and beverage industry. With a background in finance and a deep passion for innovation, Kash brings a unique blend of analytical rigor and creative problem-solving to the world of food science and formulation. Under her leadership, Icon Foods has continued to pioneer sugar reduction strategies using natural sweeteners like allulose, stevia, monk fruit, erythritol, and soluble fibers. Kash is a strong advocate for transparent labeling, functional nutrition, and providing CPG brands with concierge-level support—from custom formulation guidance and particle reduction to full-scale production planning. Known for her sharp industry insight and no-nonsense leadership style, she is committed to helping brands bring better-for-you products to market without compromising taste, texture, or integrity. Kash is also a regular contributor to thought leadership in clean label trends, gut health innovation, and female-focused wellness solutions in food and beverage. When she's not driving the next big formulation breakthrough, she's focused on mentoring emerging talent and fostering a culture of agility, ownership, and continuous improvement at Icon Foods. Website/Social Links https://www.iconfoods.com/ www.linkedin.com/in/kash-rocheleau-a0678528/ Belinda's Bio: Belinda Pruyne is a renowned Leadership Advisor, Executive Coach, Consultant, and Keynote Speaker recognized for her ability to transform executives, professionals, and small business owners into highly respected, influential leaders. As the Founder of BelindaPruyne.com, she partners with top-tier organizations, including IBM, Booz Allen Hamilton, BBDO, Hilton, Leidos, Yale School of Medicine, Landis, Discovery Channel, and the Portland Trail Blazers. Recently, she led the redesign of two global internal advertising agencies for Cella, a leader in creative staffing and consulting. She is also a founding C-suite and executive management coach for Chief, the fastest-growing executive women's network. A thought leader in leadership development, Belinda is the creator and host of the Notable Leaders Radio podcast, where she has conducted 95+ interviews with top executives and business leaders, revealing the untold stories behind their success. Previously, as Executive Vice President, Global Director of Creative Management at Grey Advertising, she oversaw a global team of 500 professionals, gaining deep expertise in client services and executive leadership. With 25+ years of experience, Belinda is a trusted advisor to startups, turnarounds, acquisitions, and Fortune 500 companies, delivering strategic, high-impact solutions in today's fast-evolving business landscape. Website: Belindapruyne.com Email Address: hello@belindapruyne.com LinkedIn: https://www.linkedin.com/in/belindapruyne  Facebook: https://www.facebook.com/NotableLeadersNetwork.BelindaPruyne/  Twitter: https://twitter.com/belindapruyne?lang=en  Instagram: https://www.instagram.com/belindapruyne/ 

We delve into the UAE National Pavilion at the 2025 Venice Biennale, titled "Pressure Cooker" with curator Azza Aboualam. An assistant professor at the College of Arts and Creative Enterprises at Zayed University Dubai and co-founder of Holesum Studio, Aboualam explains how architecture can be a cornerstone for achieving food security, particularly in challenging climates like UAE's and the broader Gulf region. Inspired by a simple question from her mother about the origin of blueberries in the UAE, Aboualam's work explored the intersection of architectural design and food production, focusing on innovative greenhouse typologies. The "Pressure Cooker" exhibition showcases how traditional and high-tech architectural elements can be reconfigured to prolong growing seasons and expand food production within the UAE. We unpack the complexities of food security as a national priority, the economic and environmental costs of imported food, and the surprising prevalence of individual-led greenhouse projects in the UAE. We also touch upon the fascinating historical context of food in the UAE, the impact of population growth on food systems, and a unique architectural cookbook attached to the project, which frames the conversation around food and built environments. 0:00:00 The UAE's Vision For Food Security0:02:40 "Pressure Cooker": Architecture and Food Flow0:03:33 The Blueberry Revelation: Origin of the Idea0:04:38 Why Food Security Is an Architectural Problem in the UAE0:05:48 The Urgency of Food Security In The UAE0:07:08 Global Warming and Food Production Challenges0:08:08 Inside The "Pressure Cooker" UAE Pavilion at the Venice Biennale 20250:10:41 A Call to Action and Moment of Reflection0:11:55 The True Cost of Food0:12:21 Greenhouses: a Common Practice in the UAE0:14:16 The "Kit-of-Parts" Innovation0:14:42 The Adaptable Greenhouse System0:16:07 Food Production in Apartment Living0:16:44 Sparking Broader Conversations0:17:30 Individual vs. Urban Scale Food Production0:19:08 Who Is Doing Food Security Well?0:20:32 Food Infrastructure in the UAE0:21:56 Regional Knowledge Sharing0:23:02 Local Food Production and Sufficiency0:23:53 Oil Revenue's Impact on Food Security0:25:01 Pressure Cooker Recipes: An Architectural Cookbook0:26:44 Engaging With Local Farmers0:28:18 Pathway to Food Independence0:29:03 Defining Food Independence0:30:54 Supermarkets: a Changing Landscape0:32:08 Historical Food Production in the UAE0:33:11 Migration and Food Systems0:35:00 Resources for Learning About Food Security0:36:51 The Problem of Food Waste0:39:17 Packaging Waste in the F&B IndustryUpcoming event

“Forces beyond your control can take away everything you possess except one thing, your freedom to choose how you will respond to the situation.” This is the quote by Holocaust survivor Viktor E Frankl that headlines a new book titled, Dealing With Feeling: Use Your Emotions to Create the Life You Want. The book comes from my guest in this episode, Marc Brackett. Mark is the founding director of the Yale Center for Emotional Intelligence and a professor in the Child Study Center, Yale School of Medicine at Yale University. Marcs research for over 25 years has focused on the role of emotions and emotional intelligence in learning, decision making, creativity, relationships, health, and performance. The quote from Viktor Frankl that came from his time in a concentration camp, and that Marc has devoted his life to, is saying that no matter what happens to us, we get to choose how we respond. And my experience of humanity is that no matter what happens to them, even great traumas, tragedies, and victimizations, what harms them more than the incident or event is how they conceive of it and how they respond. My concern is that culturally we have come into a place where we don't believe this. We feel it is our right and it's just, to respond to pain, with pain. And to say otherwise is actually offensive. Looking at the mental health stats these days, I don't think this perspective is working. This is the conversation you're about to hear with Marc Brackett. Marc previously authored the bestselling book, Permission To Feel and most recently, along with Pinterest co-founder Ben Silbermann, Marc and his team co-created the Apple award-winning app, HowWeFeel, that was designed to teach emotion skills and enhance well-being. Sign up for your $1/month trial period at shopify.com/kevin Go to shipstation.com and use code KEVIN to start your free trial. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this conversation, Nina Caviggiola and Amie Anger discuss the complexities and concerns surrounding sleepovers for children. They explore the risks associated with sleepovers, including potential exposure to inappropriate behavior and the impact on children's well-being. Amie shares her experiences as a mother and a therapist, advocating for families to set boundaries and consider alternatives to traditional sleepovers. The discussion emphasizes the importance of open communication between parents and children about safety, trust, and the reasons behind family rules. Amie Anger and her husband, Nick, live in Encinitas with their six children.  Amie received her bachelor's in psychology, and master's in social work, both from the University of Utah.  Amie went on to complete a year-long post-graduate fellowship in child and adolescent counseling at the Yale Child Study Center through the Yale School of Medicine, and a secondary post-graduate fellowship year in early childhood development and intervention, also through the Yale Child Study Center.  Amie has been a family and child therapist in private practice for 18 years.  You can find Amie on Instagram at The Real Parent, where she takes the information and strategies she uses in her clinical work and makes the information available for all families.  You can also see more of her work and find the resources she offers at realparent.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

The psychology and neuroscience of revenge.   James Kimmel, Jr. is a lecturer in psychiatry at the Yale School of Medicine, an expert on revenge, a lawyer, and the founder and co-director of the Yale Collaborative for Motive Control Studies. He is the creator of The Nonjustice System, the Miracle Court app, and SavingCain.org for recovering from grievances and revenge desires and preventing mass violence. His most recent book is The Science of Revenge: Understanding the World's Deadliest Addiction—and How to Overcome It. In this episode we talk about: The horrific and violent bullying he endured as a child—which provoked his interest in the subject of revenge The connection between revenge and addiction  Our evolutionary programming for revenge Practical strategies for when you feel wronged How to seek justice without revenge An antidote to revenge cravings And much more Join Dan's online community here Follow Dan on social: Instagram, TikTok Subscribe to our YouTube Channel Get ready for another Meditation Party at Omega Institute! This in-person workshop brings together Dan with his friends and meditation teachers, Sebene Selassie, Jeff Warren, and for the first time, Ofosu Jones-Quartey. The event runs October 24th-26th. Sign up and learn more here! To advertise on the show, contact sales@advertisecast.com or visit https://advertising.libsyn.com/10HappierwithDanHarris  

These diseases - West Nile Virus, Lyme disease, and Rocky Mountain Spotted Fever - are named for the places where outbreaks happened. But they're also all things you get from being bitten by mosquitoes or ticks. Research: Balasubramanian, Chandana. “Rocky Mountain Spotted Fever (RMSF): The Deadly Tick-borne Disease That Inspired a Hit Movie.” Gideon. 9/1/2022. https://www.gideononline.com/blogs/rocky-mountain-spotted-fever/ Barbour AG, Benach JL2019.Discovery of the Lyme Disease Agent. mBio10:10.1128/mbio.02166-19.https://doi.org/10.1128/mbio.02166-19 Bay Area Lyme Foundation. “History of Lyme Disease.” https://www.bayarealyme.org/about-lyme/history-lyme-disease/ Caccone, Adalgisa. “Ancient History of Lyme Disease in North America Revealed with Bacterial Genomes.” Yale School of Medicine. 8/28/2017. https://medicine.yale.edu/news-article/ancient-history-of-lyme-disease-in-north-america-revealed-with-bacterial-genomes/ Chowning, William M. “Studies in Pyroplasmosis Hominis.("Spotted Fever" or "Tick Fever" of the Rocky Mountains.).” The Journal of Infectious Diseases. 1/2/1904. https://archive.org/details/jstor-30071629/page/n29/mode/1up Elbaum-Garfinkle, Shana. “Close to home: a history of Yale and Lyme disease.” The Yale journal of biology and medicine vol. 84,2 (2011): 103-8. Farris, Debbie. “Lyme disease older than human race.” Oregon State University. 5/29/2014. https://science.oregonstate.edu/IMPACT/2014/05/lyme-disease-older-than-human-race Galef, Julia. “Iceman Was a Medical Mess.” Science. 2/29/2012. https://www.science.org/content/article/iceman-was-medical-mess Gould, Carolyn V. “Combating West Nile Virus Disease — Time to Revisit Vaccination.” New England Journal of Medicine. Vol. 388, No. 18. 4/29/2023. https://www.nejm.org/doi/full/10.1056/NEJMp2301816 Harmon, Jim. “Harmon’s Histories: Montana’s Early Tick Fever Research Drew Protests, Violence.” Missoula Current. 7/20/2020. https://missoulacurrent.com/ticks/ Hayes, Curtis G. “West Nile Virus: Uganda, 1937, to New York City, 1999.” From West Nile Virus: Detection, Surveillance, and Control. New York : New York Academy of Sciences. 2001. https://archive.org/details/westnilevirusdet0951unse/ Jannotta, Sepp. “Robert Cooley.” Montana State University. 10/12/2012. https://www.montana.edu/news/mountainsandminds/article.html?id=11471 Johnston, B L, and J M Conly. “West Nile virus - where did it come from and where might it go?.” The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses vol. 11,4 (2000): 175-8. doi:10.1155/2000/856598 Lloyd, Douglas S. “Circular Letter #12 -32.” 8/3/1976. https://portal.ct.gov/-/media/departments-and-agencies/dph/dph/infectious_diseases/lyme/1976circularletterpdf.pdf Mahajan, Vikram K. “Lyme Disease: An Overview.” Indian dermatology online journal vol. 14,5 594-604. 23 Feb. 2023, doi:10.4103/idoj.idoj_418_22 MedLine Plus. “West Nile virus infection.” https://medlineplus.gov/ency/article/007186.htm National Institute of Allergy and Infectious Disease. “History of Rocky Mountain Labs (RML).” 8/16/2023. https://www.niaid.nih.gov/about/rocky-mountain-history National Institute of Allergy and Infectious Disease. “Rocky Mountain Spotted Fever.” https://www.niaid.nih.gov/diseases-conditions/rocky-mountain-spotted-fever Rensberger, Boyce. “A New Type of Arthritis Found in Lyme.” New York Times. 7/18/1976. https://www.nytimes.com/1976/07/18/archives/a-new-type-of-arthritis-found-in-lyme-new-form-of-arthritis-is.html?login=smartlock&auth=login-smartlock Rucker, William Colby. “Rocky Mountain Spotted Fever.” Washington: Government Printing Office. 1912. https://archive.org/details/101688739.nlm.nih.gov/page/ Sejvar, James J. “West Nile virus: an historical overview.” Ochsner journal vol. 5,3 (2003): 6-10. https://pmc.ncbi.nlm.nih.gov/articles/PMC3111838/ Smithburn, K.C. et al. “A Neurotropic Virus Isolated from the Blood of a Native of Uganda.” The American Journal of Tropical Medicine and Hygiene. Volume s1-20: Issue 4. 1940. Steere, Allen C et al. “The emergence of Lyme disease.” The Journal of clinical investigation vol. 113,8 (2004): 1093-101. doi:10.1172/JCI21681 Steere, Allen C. et al. “Historical Perspectives.” Zbl. Bakt. Hyg. A 263, 3-6 (1986 ). https://pdf.sciencedirectassets.com/281837/1-s2.0-S0176672486X80912/1-s2.0-S0176672486800931/main.pdf World Health Organization. “West Nile Virus.” 10/3/2017. https://www.who.int/news-room/fact-sheets/detail/west-nile-virus Xiao, Y., Beare, P.A., Best, S.M. et al. Genetic sequencing of a 1944 Rocky Mountain spotted fever vaccine. Sci Rep 13, 4687 (2023). https://doi.org/10.1038/s41598-023-31894-0 See omnystudio.com/listener for privacy information.