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In this episode of The Health Revival Show, I tackle the persistent issues of SIBO, EBV, and recurring infections that plague so many of you. If you've been struggling with these health challenges, you might be wondering why they keep returning despite your best efforts. The truth is, the infections themselves are often not the primary problem; rather, the focus should be on your immune system's ability to resolve these infections. I delve into the importance of immune regulation, the role of nutrients like vitamin D, and how chronic inflammation can lead to a breakdown in immune function. Join me as we explore actionable strategies to rebuild your immune health, so you can finally break the cycle of recurring symptoms and reclaim your vitality.
In this episode of The Lancet In Conversation With, editors Niall Boyce and Bea Gómez Pérez-Nievas are joined by three leading researchers to discuss highlights from The Lancet's special issue on neurology. The conversation covers three landmark studies: the PADOVA trial of prasinezumab in early-stage Parkinson's disease, the ORATORIO-HAND study extending ocrelizumab treatment to wheelchair-using patients with progressivemultiple sclerosis, and the HEAD study comparing tau PET tracers in Alzheimer's disease — each representing a significant step forward in the field. The guests also reflect on the broader forces reshaping neurology: the push toward earlier, biomarker-guided intervention, cross-specialty learning between the multiple sclerosis, Alzheimer's, and Parkinson's fields, and emerging platforms such as CAR T-cell therapies and blood-based biomarkers. From the transformative success of spinal muscular atrophy treatment to the prospect of an EBV vaccine preventing MS, the discussion strikes a note of cautious optimism about a specialty that is entering a new therapeutic era. Visit the lancet.com to discover more
High Yield Pediatric Viral Exanthem / Illness Review: Roseola infantum, Varicella-zoster virus infection (Chickenpox), Measles, Hand, foot, and mouth disease, Epstein-Barr virus (EBV), Erythema infectiosum, Mumps, Rubellafor your PANCE, PANRE, Eor's, Physician Assistant exams, USMLE, NCLEX, nursing exams.►Support the channel by joining and becoming a member! (Thank you so much!)►Paypal Donation Link: https://bit.ly/3dxmTql (Thank you!)►INSTAGRAM: https://www.instagram.com/cramthepance/►YOUTUBE: https://www.youtube.com/channel/UCZCILePJ-E17txF-ObXlFKwIncluded in review: Slapped cheek rash, Koplik spots, Forchheimer spots, Posterior auricular lymphadenopathy, Circumoral pallor, Dew drops on a rose petal, Maculopapular rash, Vesicular rash, Parotitis, Orchitis, Oral hairy leukoplakia.Become a supporter of this podcast: https://www.spreaker.com/podcast/cram-the-pance--5520744/support.
Autoimmune disease often starts long before symptoms become obvious, and advanced testing may help uncover the hidden triggers driving inflammation, fatigue, brain fog, and chronic illness. In this episode, Dr. Jen speaks with Rubina Vojdani of Immunosciences Lab about how viruses like EBV, HHV-6, SARS-CoV-2, and Lyme-related infections can contribute to immune dysregulation, molecular mimicry, neuroinflammation, and autoimmune patterns. They discuss why conventional screening may miss key clues, how advanced panels can help identify root causes, and why monitoring markers over time can empower both practitioners and patients to intervene earlier and more precisely. Rubina Vojdani is the Lab Manager and Marketing Director at Immunosciences Lab, a clinical laboratory focused on functional immunology, autoimmunity, viral triggers, Lyme disease, and chronic inflammatory conditions. Working alongside her father, world-renowned immunologist Dr. Aristo Vojdani, Rubina helps bridge complex laboratory science with real-world clinical practice. Her work focuses on helping practitioners better understand how infections, environmental factors, and immune dysregulation contribute to chronic disease.Website: https://immunoscienceslab.comInstagram: https://www.instagram.com/immunoscienceslabFacebook: https://www.facebook.com/immunoscienceslabincPODCAST: Thank you for listening please subscribe and share! Shop supplements: https://healthybydrjen.shop/CHECK OUT a list of my Favorite products here: https://www.healthybydrjen.com/drjenfavoritesFOLLOW ME:Instagram: https://www.instagram.com/integrativedrmom/Facebook: https://www.facebook.com/integrativedrmomYouTube: https://www.youtube.com/@integrativedrmomFTC: Some links included in this description might be affiliate links. If you purchase a product through one of them, I will receive a commission (at no additional cost to you). I truly appreciate your support of my channel. Thank you for watching! Video is not sponsored.DISCLAIMER: This podcast does not contain any medical or health related diagnosis or treatment advice. Content provided on this podcast is for informational purposes only. For any medical or health related advice, please consult with a physician or other healthcare professionals. Further, information about specific products or treatments within this podcast are not to diagnose, treat, cure or prevent disease.
In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes Dr. Richard Horowitz, one of the world's leading experts in chronic illness and tick-borne disease, to discuss the groundbreaking science behind the MSIDS model and its implications for conditions ranging from Lyme disease to Alzheimer's. Dr. Horowitz shares revolutionary findings connecting chronic infections, inflammation, environmental toxins, gut dysfunction, and immune imbalance to persistent disease. He also discusses a surprising breakthrough involving Alzheimer's biomarkers and chronic Lyme treatment using his innovative dapsone protocol. This powerful conversation explores how addressing the root causes of inflammation and chronic illness may transform the future of medicine and offer hope for patients struggling with complex, unresolved health conditions.
Epstein–Barr virus (EBV) has become one of the most intensely studied topics in multiple sclerosis research. But how strong is the evidence linking EBV to MS, and could targeting the virus change the future of treatment and prevention? In this episode of the ECTRIMS Podcast, host Brett Drummond speaks with Prof. Gavin Giovannoni and Prof. Tomas Olsson about the evolving science connecting infections, immunity and multiple sclerosis. Together, they explore: Molecular mimicry and how EBV proteins may trigger autoimmune responses Whether EBV contributes to chronic CNS inflammation and disease progression Emerging therapeutic approaches including antivirals, CAR-T cells, and vaccines This conversation examines one of the most important scientific questions in MS research and the therapeutic possibilities that may emerge from it.
If you have Hashimoto's and still feel exhausted, inflamed, foggy, or “not yourself” even after trying many things, this episode is a must-listen.I'm joined again by Dr. Kasia Kines, one of the leading voices in Epstein-Barr Virus research and education, to talk about the inte- connection between EBV and Hashimoto'sEven if you have heard about this connection, this episode goes much deeper into what you need to know.• Why EBV can reactivate years later• The symptoms most people miss• The labs that actually important• Why your doctor may not be testing correctly• The connection between EBV and Hashimoto's• Mold, stress, WiFi, nutrient deficiencies, and other hidden triggers• What helps the body calm chronic reactivationThere is a lot in this conversation that people with Hashimoto's are rarely told, especially when it comes to why symptoms can continue even when thyroid labs start to look better.For full show notes, please see:https://innatopiler.com/podcasts/why-ebv-keeps-reactivating-in-hashimotos-with-dr-kasia-kines/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping If you are struggling to lose weight with Hashimoto's, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto's, please check out Inna's 9 Day Exhaustion Solution at innatopiler.com/energyIf you don't yet know your thyroid type, please be sure you sign up for Inna's next free training at InnaTopiler.com/zoomcallFor more information about everything Hashimoto's please visit InnaTopiler.com
If you have not been yourself since a virus, this episode is for you. Dr. Alison goes deep on the post-viral brain in Episode 2 of the May brain health series. Long COVID, EBV reactivation, mast cell activation, POTS, and the neuroinflammation that ties them all together. Includes the full personal story arc Dr. Alison previewed in Episode 1, from EBV in high school through the February 2026 long-hauler symptoms that hit three weeks after a COVID infection. Plus the labs to actually order, the protocols she uses with her patients and herself, and the research that finally validates what women in chronic illness communities have been saying for decades. Topics covered: microglial activation, blood-brain barrier disruption, autonomic dysfunction, mast cell activation syndrome, EBV reactivation patterns, post-viral thyroiditis, the DUTCH test, monolaurin and other antivirals, methylation support, the nicotine patch protocol, and the difference between productive rest and real rest. The Mama Brain Reset Doors open today, May 11. The 30-day root cause program for brain fog, post-viral patterns, and the perimenopausal brain. Investment $247 all-in. Doors close May 24. Comment MAMA on Dr. Alison's Facebook post or visit littleblackbagmedicine.com. Subscribe to the series Episode 3: The Brain-Hormone Conversation (drops May 18). Episode 4: The Forgotten Brain Foundations (drops May 25).
In his weekly clinical update, Dr. Griffin and Vincent Racaniello note the uncertain future of the National Science Foundation amid shifting U.S. funding priorities and governance; the rise of China as a global research powerhouse; ongoing advances and controversies in vaccines shaped by the World Health Organization and the Centers for Disease Control and Prevention; vaccine policy battles in Florida; European approval of the moderna mCOMBRIAX, COVID-19 and influenza vaccine, the mounting evidence supporting preventive vaccination strategies including that for HPV and the HepB birth dose; the spread of drug-resistant infections and the resurgence of HIV in Zambia; and the enduring public trust in scientists despite political turbulence, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the efficacy of the influenza vaccine for children, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, use of remdesivir for RSV, how administration of Paxlovid did not affect hospitalization of high-risk vaccinated patients, where to go for answers about long COVID-19, if SARS-CoV-2 infection may facilitate EBV reactivation, exercise for treating long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Entire NSF science advisory board fired by Trump administration (Nature) United States v. Arthrex, Inc.(Harvard Law Review) United States v. Arthrex Inc. [SCOTUSbrief] (Federalist Society) China could be the world's biggest public funder of science within two years (Nature) The Vaccine Skeptic in Trump's New C.D.C. Leadership Team (NY Times) World Immunization week: Largest catch-up initiative delivers over 100 million childhood vaccinations (WHO) Pigs are flying!: Florida Republicans refuse to take up DeSantis bill loosening vaccine mandates (NY Times) Moderna Receives European Commission Marketing Authorization for mCOMBRIAX, Moderna's mRNA Combination Vaccine Against Influenza and COVID-19(moderna) America First! AIDS Creeps Back in Parts of Zambia, a Year After U.S. Cuts to H.I.V. Assistance (NY Times) Emergence of Extensively Drug-Resistant Shigellosis — United States, 2011–2023 (CDC: MMWR) Scientists Esteemed by Public, with Vaccine Scientists Seen as Similar to Scientists in General (Annenberg: Public Policy Center, University of Pennsylvania) RFK Jr. is holding up $600M in vaccines for poor countries (Politico) Trump Withdraws Nomination of Casey Means for Surgeon General (NY Times) What? Benefit of preventive strategies like vaccination? Incidence of human papillomavirus infections in women aged 27 years and older in the US: A federated data network study (International Journal of Infectious Diseases) Economic Impact of Delaying the Infant Hepatitis B Vaccination Schedule (JAMA Pediatrics) Impact of Removing the Universal Hepatitis B Birth-Dose Vaccination in the US (JAMA Pediatrics) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Measles Dashboard (South Carolina Department of Public Health) Utah measles outbreak response (Utah Department of Health and Human Services) Utah Measles Dashboard (Utah Department of Health and Human Services) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Dangers of measles infection (NY Times) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA) WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP) FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP) Weekly surveillance report: cliff notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option (Xofluza) Influenza Vaccination Coverage Among Nursing Home Residents and Health Care Personnel — United States, 2024–25 Influenza Season (CDC: MMWR) Pediatric Vaccine Effectiveness Against Influenza Hospitalization And Outpatient Visits: 2021–2024 (Pediatrics) Influenza Vaccine Effectiveness in European Primary Care Pediatric Practices: 2022–2024 (Pediatrics) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Respiratory Diseases (Yale School of Public Health) Impact of universal nirsevimab prophylaxis in infants on hospital and primary care outcomes across two respiratory syncytial virus seasons in Galicia, Spain (NIRSE-GAL): a population-based prospective observational study (LANCET: Infectious Diseases) First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients (JID) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients(NEJM) Same Pill, Different Impact — Reassessing the Efficacy of Nirmatrelvir–Ritonavir(NEJM) Paxlovid doesn't reduce hospitalization, death rates in vaccinated high-risk COVID outpatients, trial shows (CIDRAP) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia: Columbia University Irving Medical Center) The answers: Long COVID Acute COVID-19 is associated with altered CD8 T-cells indicative of impaired ability to control Epstein–Barr virus reactivation (Medical Microbiology and Immunology) Exercise and Weekly Sirolimus (Rapamycin) in Older Adults: RAPA-EX-01 Randomised, Double-Blind, Placebo-Controlled Trial (Journal of Cachexia, Sarcopenia and Muscle) Reaching out to US house representative Letters read on TWiV 1318 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.
In part one of this series, Dr. Justin Abbatemarco and Dr. Paulus Rommer discuss the relationship between Epstein-Barr virus and multiple sclerosis, as well as the questions that still remain unanswered. Show citation: Vietzen H, Kühner LM, Berger SM, et al. Epstein-Barr Virus Antibodies to Differentiate Multiple Sclerosis From Other Neuroinflammatory Diseases. JAMA Neurol. Published online March 9, 2026. doi:10.1001/jamaneurol.2026.0240 Show transcript: Dr. Justin Abbatemarco: Hello and welcome. I just finished interviewing Paulus Rommer on his article published in JAMA Neurology, Epstein-Barr Virus Antibodies to Differentiate Multiple Sclerosis From Other Neuroinflammatory Diseases. Paulus, could we maybe talk about this relationship that we've understood about multiple sclerosis and Epstein-Barr virus? And maybe the points that still remain unanswered? Dr. Paulus Romme: There's a very long story behind this because in 1868, Pierre Marie, a student of Charcot was talking about that multiple sclerosis is a sequelae of an infection disorder. By this, we now know that there's a long story. There have been associations between infectious mononucleosis, EBV infection, multiple sclerosis. Also, the migration studies really fits very well in this. So there have been an association, but then, in 2022, there was the US Army study, Bjornevik and Ascherio, who really have shown that there is almost no multiple sclerosis without EBV infection. But still, we do not know why almost all of our patients have EBV infection, but only very small subset have multiple sclerosis. But this is very important to get a deeper understanding, but this is still unknown. Dr. Justin Abbatemarco: This story of EPV and multiple sclerosis continues to evolve. And your work, as we talked about on the podcast, has really helped inform that discussion as well. And we still need to understand, outside of the initiation of the disease, how it drives the pathophysiology years after that initial infection. But it's really helpful to understand this in the larger set and now maybe using it as a biomarker to help us with our other neuroinflammatory diseases, so we'll discuss that the next episode. Again, I was just speaking with Paulas Rommer on his article in JAMA Neurology, Epstein-Barr Virus Antibodies to Differentiate Multiple Sclerosis From Other Neuroinflammatory Diseases. Paulus, thank you.
Dr. Justin Abbatemarco talks with Dr. Paulus Rommer about the evolving understanding of Epstein-Barr virus (EBV) and its role in multiple sclerosis (MS), including recent research on EBV antibodies as diagnostic markers and potential therapeutic targets. Read the related article in JAMA Neurology. Disclosures can be found at Neurology.org.
You broke a 5-day dry fast. Two days later, you've got a cold sore, a shingles patch, or that crushing post-mono fatigue is back. Almost everyone blames the fast. They're looking at the wrong window.The dry fast is the safest period your immune system experiences all year. Autophagy is destroying virus-occupied cells. Ketones starve viruses of the glucose metabolism they need. mTOR (the growth signal viruses hijack to replicate) is shut down. And NK cell activity is climbing. Inside that fasted state, viral replication is mechanically and metabolically near-impossible. That's why most people don't flare during the fast itself.The danger is the refeed. The moment food comes back, mTOR turns back on, autophagy shuts off, your T-cells are still parked in bone marrow, cortisol is still peaking, and T3 is still crashed. For 24 to 72 hours your antiviral defences are at zero — and any virus that survived the fast now has an open road to refill the reservoirs the fast just cleared. Worse, it can spread to nerve cells it never previously occupied.In this video I break down:— Why the dry fast creates a near-impenetrable antiviral state (4 mechanisms)— Why the refeed is the highest-risk window in the entire protocol (5 mechanisms)— Why a botched refeed leaves chronically ill patients MORE infected than they started— The bridge strategy: dry fast → water fast → controlled refeed with antivirals already on board— The full pharmacological stack: T3, L-lysine, monolaurin, acyclovir, ivermectin— Early warning signs of reactivation in the refeed window (and what to do)— Why this gets dramatically easier from cycle 3 onward— The T3 off-ramp as the second high-risk window most people missThis isn't a reason to fear fasting. It's the map of when the danger window opens and how to close it before food can.
In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan explores the complex and rapidly evolving science behind Long COVID and autoimmune disease with Dr. Aristo Vojdani, a leading expert in immunology and functional medicine. Dr. Vojdani shares decades of groundbreaking research into how the immune system becomes dysregulated, revealing how infections, environmental toxins, and food antigens can trigger autoimmune reactions through mechanisms like molecular mimicry and gut permeability. The conversation dives deep into how SARS-CoV-2, Epstein-Barr Virus (EBV), and HHV6 contribute to Long COVID and neuroautoimmune conditions, as well as how early detection through advanced laboratory testing may help prevent disease progression. This episode offers powerful insights for both clinicians and patients seeking to understand the root causes of autoimmunity and chronic illness in the post-COVID era.
Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions: Christina: Dr. Cabral, thank you so much for all you do for our community. My question is about oral health and specifically the use of the 360 one-piece toothbrushes that take 30 seconds to clean the teeth (I.e. Autobrush). Do you think they are as effective as the sonic electric toothbrushes and what is your opinion on them? Additionally, one can choose the fluoride free toothpaste versions, but they require a foaming agent to work. I like the fact that these toothbrushes require less time overall and seem to clean all the teeth, but am a little concerned about the foaming toothpaste that are required for them to wok. Thank you! Barbara: What is the 12,000 FU that you referred to in your post. Tricia: Hi Dr. Cabral - I'm trying to figure out if I should take your berberine or daily gluco support. Can you please explain the difference, and which one might be better for a 56-year-old female that does struggle to keep weight off and balance blood sugar. I'm not diabetic but I watch it closely. Thank you! Alex: Hi Dr. Cabral, I am a 37-year-old female diagnosed with JAK2-positive essential thrombocythemia five years ago. My diagnosis followed after an initial finding of iron deficiency. It was confirmed through a bone biopsy. I have recently started following your show and am focused on finding the root cause. I would like to avoid progressing to chemotherapy medications if at all possible. To manage inflammation and support detoxification, I maintain an anti-inflammatory diet, exercise at least five days a week, use a sauna, and take various supplements. My biggest symptom with this disease is fatigue. Could you point me in the right direction of finding the root cause and help lowering my platelet count? Thank you! Alex Samantha: Hi Dr Cabral, I went into an adrenal crisis in 2023 and was diagnosed with Primary Addison disease and hashimotos. I also have undifferentiated connective tissue disease. I take steroids and thyroid mediation, and also work with an N.D. for recurring EBV, h pylori, and candida. I have reduced the hashimotos antibodies drastically and have hope to eventually go into remission, but my question is, is it possible to heal or go into remission with Primary Addison disease and not be dependent on steroids? Or is it true that with primary Addison disease, the adrenals are "toast?" Though I have reduced the hashimotos antibodies, the 21-hydroxlase Addison antibody is still present. Would love any tips or suggestions. Thank you!! Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions! - - - Show Notes and Resources: StephenCabral.com/3697 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Long Covid-19, EBV, CMV, Parvo-Virus B19–these are the viral infection that when chronic hijack your mitochondria and immune system, weakening them–which results in unrelenting, chronic fatigue and various fatigue disorders. Join Dr. Ernst as he explain what each virus is, where you get them from and best of all a 3 step process to remove chronic viral infections.See omnystudio.com/listener for privacy information.
forever young - Ernährung, Bewegung, Denken, Gesundheit und Fitness
EBV, Epstein-Barr-Virus, Immunsystem, Erschöpfung, Laborwerte, 47 essentielle Stoffe
Guest: Dr. Daniel Peeper is a Professor in Functional Oncogenomics at VU University Amsterdam, heading the Department of Molecular Oncology & Immunology and chairing the Research Faculty Council Board at the Netherlands Cancer Institute. His lab employs function-based, genome-wide screens and other advanced technologies to develop concepts for rational combinatorial cancer treatment, targeting both cancer and immune cells more effectively. Featured Products and Resources: Obtain highly purified cells in a single step with the Easy 250 EasySep Magnet. Download a free wallchart on the production of CAR T cells. The Immunology Science Round Up Genomic Insights into EBV – Researchers used genome sequencing data to identify genetic and lifestyle factors linked to control of persistent Epstein–Barr virus (EBV) infection and its association with autoimmune diseases. Cholinergic Control of B Cells – Acetylcholine signaling in germinal center B cells helps regulate their selection and differentiation to shape high-affinity antibody responses. Targeting Persistent HIV Clones – Persistent HIV reservoir T cell clones resist immune clearance but remain vulnerable to sustained cytotoxic T cell pressure. T Cell Engagers in Autoimmunity – CD19×CD3 and BCMA×CD3 T cell engagers improved disease outcomes in patients with treatment-refractory antisynthetase syndrome and systemic sclerosis. Image courtesy of Daniel Peeper Subscribe to our newsletter! Never miss updates about new episodes. Subscribe
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Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks… Ryan: First off, I would like to say thanks for all that you do in supporting a healthy community, it's greatly appreciated. My question has to do with what and how much physical activity should you do while you are sick, along with what additional health modalities would you suggest. When you are sick or feeling like you're getting sick, do you continue hitting your 10,000 steps per day? Weight lift? Cardio? HIIT? Continue working out but at a reduced intensity? Should you substitute some activity for red light? Sauna? Yoga? And how would this differ from a cold to a fever? Thanks again! Ann: Hi Dr. Cabral and as always thank you for being such a champion for us out here :) A friend swears that Milk Thistle helped her when she was battling liver cancer. I have NAFLD and am working to reduce it, and besides the ways you have outlined to help (episode 3017), I'm wondering if milk thistle could be a good addition? Thank you so much - have a blessed day:) Dawn Marie: Hi, Dr. Cabral. I had mono as a child, and again in 2023 when I was 48 years of age. In 2023, I was on day 17 of the detox when the mono re-emerged and I was quite sick, almost requiring hospitalization--liver enzymes quite high, thickening of gallbladder walls, and enlarged spleen. My doctor actually wrote me a referral to a surgeon to likely have my gall bladder removed! Thank goodness, after years of listening to your podcasts, I knew to do some research and discovered that after I recovered from the mono, all would return to normal and they did. My understanding is that Epstein-Barr "lives" in the liver and is difficult to fully heal from. I'd like to "kick it out" for good. Is there a way to fully heal from EBV? Is there any risk of it re-emerging if I try to do another 21-day detox? Dylaini: Hi Dr Cabral! Thanks for all you do, you're a wealth of knowledge! I am working with a lot of tinnitus clients and some claim it's from being in the military and being exposed to loud noises, do you think this is simply a "stress" on the body and isn't necessarily a permeant issue from being exposed to loud noises? Thanks again! Josephine: Hi Dr Cabral, you've been an amazing ing help to me over the years, thank you. I'm a 44year old woman living in Australia. I have idiopathic guttate hypomelanosis (IGH) on my legs and arms. I get this much more so than brown pigment spots. I understand sun protection is the best way to prevent this, however I'm wondering if you have any tips for how to treat it (most sources say pigment won't come back) and also what supplements or topical treatments (excluding sunscreen) might make the skin less susceptible. Thanks! Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3677 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Dr. Monty Pal and Dr. Ari Rosenberg discuss the evolution of treatment strategies in head and neck cancers, including the challenges of treating both HPV-positive and HPV-negative disease and the emergence of blood-based biomarkers to advance personalized therapy across different subtypes. TRANSCRIPT Dr. Monty Pal: Hello and welcome to the ASCO Daily News Podcast. I'm your host, Dr. Monty Pal. I'm a medical oncologist, professor, and vice chair of academic affairs at the City of Hope Comprehensive Cancer Center in Los Angeles. Today, we're going to explore the evolving landscape of treatment strategies in head and neck cancer management, including locoregionally advanced head and neck squamous cell carcinoma, which happens to be on the rise in United States, in part due to spike in HPV-mediated oropharyngeal cancers. We're also going to discuss the emerging strategies of using blood-based biomarkers to really advance personalized therapy. Joining me for this discussion is Dr. Ari Rosenberg. He's a medical oncologist focused on head and neck cancer, and he's an associate professor – congratulations on the recent promotion – at the University of Chicago. The University of Chicago has really produced luminaries in this field, Dr. Rosenberg included. I've had the pleasure of getting to know Dr. Ezra Cohen over the years, who really had his grounding there, and of course Everett Vokes, former ASCO President. I'm really looking forward to this conversation, Ari. Thanks so much for joining us. Dr. Ari Rosenberg: Thanks, Monty. Thanks for the invitation. Dr. Monty Pal: You got it. And just a quick note for our listeners, our full disclosures are going to be in the transcript at the end of this episode. So let's start with the basics, if you don't mind. So, head and neck cancers are very diverse and they're challenging, right? In the sense that they're near vital organs, the treatments, you know, as we all saw during fellowship, if not now in clinical practice. They can really have such a major impact on vital organ function, speech, swallowing, et cetera. Can you just comment on head and neck cancers that are on the rise in the U.S.? I alluded to this briefly. Particularly, we've heard this in the context of colorectal cancer and so forth. Are you actually seeing younger adults being affected by this? Dr. Ari Rosenberg: Yeah, thanks for that. The vast majority of head and neck cancers are head and neck squamous cell carcinomas, as I'm sure many of the listeners recall as well from fellowship or their current training. And as you alluded to, the organ function, long-term and functional quality of life outcomes are quite important, particularly in the context that these develop in high value real estate, parts of our head and neck area that we use for speaking, swallowing, all sorts of other essential functions as well. As you also alluded to, we think of this in two different particular subtypes of head and neck cancer. The historical head and neck cancer from 50, 60 years ago was almost exclusively related to carcinogen exposure, tobacco, alcohol use, and that subtype of carcinogen-induced head and neck cancer has been slowly declining. However, over the last now several decades, we've been seeing an increase in primary oropharyngeal squamous cell carcinoma, mostly tonsil, base of tongue. These are attributable to HPV, human papillomavirus exposure. And that's now the majority of the head and neck cancers that we tend to see in our clinic. As you also alluded to, these have very different prognoses as well. HPV-related head and neck cancer has a much more favorable prognosis where much of the interest has been in can we de-intensify to optimize long-term function? But then the non-HPV-related head and neck cancer, or what we call HPV-negative head and neck cancer, continue to be very, very challenging. We only managed to cure about half of these folks, with many of these patients developing the current disease. These patients, in addition to being difficult to treat, also have major impacts both in terms of the treatments they undergo as well as their disease that can impact their function and quality of life. And you hinted at this a little bit, but we have been seeing an increase in younger patients with HPV-negative head and neck cancer as well, which is quite concerning. Younger patients, oftentimes never smokers, never drinkers, who are developing non-HPV-negative head and neck cancer. And that's been a little bit of a more recent trend that we've been seeing as well. So, definitely a lot of work to be done to optimize and improve outcomes across all of these different head and neck cancer subtypes. Dr. Monty Pal: I mean, I'm just curious, you know, in the context of colorectal cancer, one of the things that we talk about is the potential role of the microbiome driving some of these young-onset cancers with, you know, perhaps there being an impact on, for instance, inflammation and the gut and what have you. Tell me about head and neck cancer. Is this anything known as to why younger patients might be getting diagnosed with non-HPV type cancers? It's odd to me. Dr. Ari Rosenberg: Yeah, it's a great question. A lot of people are working on it. I think we folks have hypotheses, but it hasn't totally panned out exactly what's going on there. It does have a little bit more of a tendency towards women, whereas historically head and neck cancer is much more common in men than it is in women. But lots of people working on that, whether it's related to chronic inflammation, whether it's related to the microbiome. Whether it's related to dental exposure, dental work. So, a lot of folks trying to parse that out because I agree with you, it needs to be identified alongside improving treatment paradigms for these patients, the young ones and the older patients as well. Dr. Monty Pal: Interesting, interesting. You know, one of the phenomena that was sort of coming around when I was in training 25 years ago was this role of sort of induction therapy for head and neck cancers. And of course, it's really come full circle now to include checkpoint inhibitors and so forth. Tell me a little bit about this and how you apply it, maybe in an HPV-mediated context, maybe in a non-HPV context. Dr. Ari Rosenberg: Yeah, absolutely. Induction chemotherapy, as you alluded to, or neoadjuvant chemotherapy, depending on what the locoregional treatment approach is. Similar to other cancer types where systemic control early on has many potential advantages in this setting. Now, in head and neck cancer, even though induction chemotherapy is quite active in head and neck cancer, both HPV-positive and HPV-negative with pretty good response rates. A survival advantage for all comers with local regionally advanced disease remains unproven. There's been two randomized trials, both underpowered, but essentially did not show a survival advantage, showing that induction chemotherapy for all patients with locoregionally advanced and neck cancer can't be justified for a survival advantage. That being said though, there remains a number of potential advantages of giving induction or neoadjuvant chemotherapy, of course, improving systemic control and debulking the disease early on has potential advantages, and predicting the responsiveness to subsequent radiation treatment. We know for some time in head and neck cancer that the percentage of shrinkage or the response to induction chemotherapy actually predicts outcome related to radiation as a dynamic biomarker where response can be used to select patients, for example, for de-escalated radiation has been an area of active investigation, active research. And it also remains a key opportunity to evaluate predictive biomarkers and understanding pre and post treatment to better understand the biology. I'll just add to your question that recently over this past year, we also saw phase 3 data for neoadjuvant immunotherapy for a subset of head and neck cancer that is surgically resectable. And so that's reintroducing the potential benefit in the immunotherapy era of incorporating immunotherapy in the neoadjuvant or the induction setting as part of the evolving treatment paradigm for these diseases. Dr. Monty Pal: That's really interesting. And you kind of alluded to already several topics that I plan to hit on, you know, for instance, the role of immune checkpoint inhibitors, induction, chemotherapy, and so forth. And you started to touch on biomarkers. And of course, I think that's something near and dear to many of us in academic oncology. One thing that we've started talking a lot about in the context of colorectal cancer is circulating tumor DNA. How do you think this might fit in the context of head and neck cancer? Can you give us a flavor for that? Dr. Ari Rosenberg: Yeah, absolutely. In head and neck cancer, the current landscape is most developed for circulating tumor DNA for HPV-related head and neck cancer. The advantage of HPV-related head neck cancer is that you have a distinctive HPV DNA that does tend to spill out into the peripheral blood and can be detected using various different blood-based assays. And because of that advantage as a tissue agnostic approach, it turns out that a number of HPV DNA plasma assays are actually quite sensitive and quite specific. And a number of them have indeed been commercialized. Of course, not only for detecting a baseline, but also grading responsiveness during treatment and probably most importantly in the post-treatment surveillance setting, the detection of HPV DNA in the plasma remains a very important and substantial predictor of developing recurrent disease. There's been a number of trials that have been emerging looking at ctDNA and HPV-related head and neck cancer, using it, for example, as a strategy to deescalate patients. That was something we saw this past ASCO from the Dana-Farber group, and also using it to early detect recurrence and potentially intervene earlier for patients with minimal residual disease positivity. So, that remains evolving and as many folks are, I think, already using it in the clinic. But ctDNA also has a lot of potential for HPV-negative head and neck cancer. This is actually a bit more challenging to develop because you don't have that HPV DNA that you can track predictably because the tumor is an HPV- negative disease are much more heterogeneous, but there are a number of data that are coming out both for personalized assays such as Signatera or some of the other assays that require tumor. Unlike colon cancer, which you referenced, where most patients get surgery upfront, in head and neck cancer, many of the patients receive non-surgical pre-chemoradiation. So sometimes the amount of tumor available to generate a personalized assay is more limited and can be one of the challenges that we see in head neck cancer. But certainly that also seems to be emerging. And there's also further assays that are being developed for HPV-negative head neck cancers, such as methylomic signatures and others that may be tissue informed or tissue agnostic. And these are also emerging, particularly in the post-treatment surveillance setting as strong predictors of recurrent disease. So while we're certainly behind some of these other more common tumor types, colon cancer, lung cancer, we're right there with them and more and more trials are going report out, including a number of trials in our upcoming [University of Chicago] Head and Neck Cancer Symposium where I'll be presenting some data and others in the field will be presenting some data looking at ctDNA both for HPV-positive and for HPV- negative to try to improve outcomes for these patients. Dr. Monty Pal: That's so interesting. I've got to tell you that in kidney cancer, what I deal with day to day is a very low shedding disease, right? So techniques as opposed to ctDNA looking for tumor-informed information, that might be less preferred to something like methylomics where you might not necessarily be so contingent on what's happening in the primary tumor. I'm really interested in you mentioning that. Just a point of clarification, this is something I'm trying to wrap my head around. You'd mentioned circulating tumor HPV DNA, right? I assume this is markedly different from just looking for HPV titers in the patient, right? So is this actually incorporated elements of HPV within, you know, essentially host genome, if you will? Dr. Ari Rosenberg: Yeah, correct. This is circulating tumor HPV DNA. And we think of it biologically as a plasma-based tumor DNA biomarker that's specific for HPV-related head and neck cancers. Dr. Monty Pal: Got it, got it. It makes me wonder whether or not this might be applicable to diseases like cervical cancer and so forth where there's also extensively, you know, biology driven by HPV. Is that fair? Dr. Ari Rosenberg: Yes, definitely. And in the head and neck cancer field, much of this ctDNA actually was derived from a different viral mediated head neck cancer, is less common in the U.S., but nasopharyngeal cancer, which is oftentimes associated with EBV. That has been a biomarker for quite some time in nasopharyngeal cancer. Of course, in places where EBV-associated nasopharyngeal cancer, is endemic, such as East Asia, this has been around for quite some time, but we've been using that in the U.S., and there's been trials that have used EBV DNA plasma to predict recurrence and stratify for adjuvant treatment, for example. And so now with HPV, it's much more applicable to our US population because the vast majority of our head and neck cancer patients that we see in the US that are viral mediated in the US tend to be HPV-related. So having assays that we can use to improve outcomes for that biological subset remains of particular interest for us. Dr. Monty Pal: Yeah, that's fascinating. By the way, for the fellows listening, there's tons of boards pearls here that Dr. Rosenberg shared, EBV-associated cancers, the role of HPV and treatment association. So if you're recertifying anytime soon, I definitely think there's notes to take from this conversation indeed. I wanted to shift gears a little bit. And obviously, you're a prolific researcher. I don't think anyone goes through their fellowship in medical oncology without recounting these experiences of our head and neck patients really suffering from treatment-related toxicities. It's a real challenge. And I'm just wondering, I know a big body of work that you're focused on is really using multimodality treatment paradigms to perhaps reduce the cumulative treatment burden of patients with head and neck cancers. Can you talk about that a little bit? Dr. Ari Rosenberg: Yeah, definitely. Thanks for the question. And before I start going into some of the strategies, I'll just say that head and neck cancer, this is particularly for the fellows that are listening as well, just in reference to your prior comment, that this is really a multidisciplinary disease. At our center, all head and neck cancer patients are seen upfront at that first visit by all three specialties, med onc, rad onc, and surgery, because the choice and sequencing of modalities to optimize not only survival, but also functional quality of life outcome is so critical. And I think that's probably the biggest takeaway for anyone who treats a lot of head and neck cancer or will be treating a lot of head and neck cancer in the clinic. But in terms of more specific attempts at trying to optimize some of those parameters that you described, we really think about these separately in terms of HPV-positive and HPV-negative head and neck cancer. For HPV-positive head and neck cancer, the cure rates are quite high with chemo radiation, although not for everyone. There's still about 15, 10 to 15 % of folks that will develop a recurrence. But for the vast majority of patients, standard chemoradiation is quite a cure to therapy, but the toxicity associated with that can be quite substantial. And so there's been a number of attempts to try to deescalate treatment. It turns out that deescalating everyone with locoregionally advanced HPV-positive head and neck cancer is not a good strategy because it's not able to select out the patients that really do need full dose treatment. And we have seen some negative trials that show inferior outcomes when everyone is deescalated. But what does remain promising is again, trying to select out who the best candidates are for deescalated treatment. The folks at MSK have hypoxia imaging that they're using in trials that looks quite promising to select for the more favorable deescalatable biology. At our center, we've been interested in using induction chemotherapy to stratify response and select patients for deescalated treatment with excellent survival outcomes and reduce toxicity with deescalated treatment. And more recently, ctDNA that us and other groups, such as the Dana-Farber group, is using. And that also looks quite promising. Again, how do you select the patient who will do well with less radiation versus the ones that really need the full doses and volumes of radiation? And then for HPV-negative head and neck cancer, this is a much trickier disease because already the survival outcomes are not like we want it to be. Trying to figure out how to improve survival outcomes remains an important thing. Using immunotherapy seems to be one of the key cornerstones to that. But these are patients that also suffer from a lot of toxicity related to their treatment. We completed a trial not too long ago that we published this past year where we, in HPV-negative head and neck cancer patients, de-intensified the radiation for responders to neoadjuvant chemoimmunotherapy. And those patients did similar, if not even a little bit better, than the non-responders who got full dose treatment. So something that does warrant further investigation as well. How do we not only improve survival for those patients, but also reduce some of the long-term toxicities? Dr. Monty Pal: This is brilliant. I'm taking so many notes as you were mentioning these items. There are so many areas where I think the research crosses over. I already mentioned, know, ctDNA, for instance, and metabolomics and the places where that might apply to kidney cancer. The hypoxia imaging really caught my ear too. Obviously, kidney cancer is disease highly predicated on hypoxia. So thank you for all of this. We've got about a minute or so. So, I'm going to ask you for a really tall task here. Can you tell us what you foresee being some of the biggest challenges that sort of lie ahead and head and neck cancer. You've already kind of alluded to it with ongoing research, but if you had to pick maybe 2, 3 problems, the very most that we really need to get to and head and neck cancer, what would that be? Dr. Ari Rosenberg: Yeah, that's a great question. Obviously, lots of things to be done, but if I'm going to limit it to just a couple, I would say number one is really trying to improve the survival for HPV negative local regionally advanced head and neck cancer. We talked early on about how we are seeing, you know, of course we see many of these people that were smokers and drinkers, but also seeing these in younger patients, in patients without a history of tobacco use. Some of these are very biologically aggressive and we need better treatments beyond surgery, beyond chemo radiation, beyond immunotherapy to improve outcomes for these patients and cure more of them. So, I would say that's one big area. And the other is, which we didn't speak about so much in this talk, but remains one of the biggest challenges that we see in the clinic is the recurrent metastatic head and neck cancer patients. This is an incredibly challenging disease to treat, not only with poor survival, but also with substantial impacts on quality of life and function. mean, these are bad recurrences that cause a lot of pain, functional deficits, really impacts quality of life as well. So developing novel therapies, many of which are currently in clinical trials and many of which are currently continuing to be developed, remains so critical. How do we develop better systemic therapies, better targeted therapies, better biomarkers for recurrent metastatic head neck cancer to improve their survival and quality of life and functional outcomes. Those are the two big areas that require the most work at this time within the head and neck cancer field. Dr. Monty Pal: That's brilliant. I mean, I have to tell you I could probably talk to you all day about this, such a fascinating topic. It's a very exciting time in the field. Thank you, Dr. Rosenberg, for all your incredible contributions and thanks for sharing with us your insights on the ASCO Daily News Podcast. Dr. Ari Rosenberg: Yeah, and thanks for the introduction. Hope to do it again soon. Dr. Monty Pal: And many thanks to our listeners for your time today. If you value the insights that you hear from the ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. More on today's speakers: Dr. Monty Pal @montypal Dr. Ari Rosenberg @AriRosenbergMD Follow ASCO on social media: ASCO on X ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. Monty Pal: Speakers' Bureau: MJH Life Sciences, IntrisiQ, Peerview Research Funding (Inst.): Exelixis, Merck, Osel, Genentech, Crispr Therapeutics, Adicet Bio, ArsenalBio, Xencor, Miyarsian Pharmaceutical Travel, Accommodations, Expenses: Crispr Therapeutics, Ipsen, Exelixis Dr. Ari Rosenberg: Stock and Other Ownership Interests: Privo Technologies Consulting or Advisory Role: Nanobiotix, EMD Serono, Vaccitech, Novartis, Eisai, Astellas Pharma, Regeneron, RAPT Therapeutics, Geovax Labs, Janssen, Summit Therapeutics Speakers' Bureau: Coherus Biosciences Research Funding (Inst.): Hookipa Biotech, EMD Serono, Purple Biotech, Bristol-Myers Squibb/Celgene, BeiGene, Abbvie, Astellas Pharma, Pfizer, Janux Therapeutics
Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks… Sami: Hi Dr. Cabral! I am currently doing your 21 day detox. I am loving every second of it. For one of my meals I decided to have red beats as my carb/veggie. I had this for two dinner meals in a row and noticed the redness in my stool showed up the next morning after my second meal and then 48 hours after my second meal. I read online that eating red beats can help display gut transit time. I know red beats normally turn your stool a red/pink color in general. Are red beats a good natural/home remedy to decide gut transit time? Or would something like the blue poop test work best? Larissa: Hello! My patient recently tested positive for EBV VCA IgM antibodies with positive EBV IgG antibodies but negative early EBV antigen and EBNA levels. She is experiencing fatigue. Would you consider this an acute or reactivated infection? Could it be a false positive? Would you treat this? Thank you in advance! Katrina: As I explore your protocol options and tests, how would having gastric bypass, 22 years ago affect the results to achieve optimal health. Will the products be effective due to potential absorption issues? Ateba: Hello Dr.Cabral, I've had some bony growth behind my teeth over the last decade. I believe it's called Mandibular Tori. It seems to have grown quite a bit the last few years. My dentist says it's from jaw clenching, which I had during sleep for quite some time, but I've also heard other things (nutrition deficiencies/toxicity's etc). Don't have parasites according to my stool test, just excessive stress. Wondering if you have any recommendations for this condition. God Bless. Lisa: Hi Dr Cabral! I listen to you daily, thank you for your knowledge and swear by your functional detox a few times a year! I have been waking up recently (about the last year now) with a mouth full of saliva and I'm forced to get up to spit. I sleep really well - straight through the night, yet this is a bit concerning to me. Any ideas? Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3663 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
In this episode of the Oncology Brothers podcast, we dived into the current treatment landscape for head and neck cancer. We welcomed Dr. Fangdi Sun, a head and neck medical oncologist from Stanford University, to discuss key topics including: • The importance of initial workup and the role of biomarkers, including HPV and EBV testing. • Treatment paradigm for early-stage and locally advanced head and neck cancers, focusing on the differences between HPV-positive and HPV-negative disease. • The evolving role of immunotherapy and the new perioperative approaches in treatment. • Insights into managing metastatic disease, including the use of PD-L1 scores and systemic therapy options. • The significance of multidisciplinary collaboration in optimizing patient care. Whether you're a healthcare professional or simply interested in oncology, this episode provides valuable insights into the complexities of head and neck cancer treatment. Don't miss out on this informative discussion! Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Subscribe to our channel for more episodes as we continue to bridge the gap in oncology! #HeadAndNeckCancer, #HPV, #Immunotherapy, #MultidisciplinaryCare, #OncologyBrothers
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TWiV reviews compelling virology themes for 2024, as heard in our 98 episodes, including 22 guests. Hosts: Vincent Racaniello and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2026 Dismantling of science and public health in the US including TWiV 1199, TWiV 1191, TWiV 1197, TWiV 1203, TWiV 1205 , TWiV 1209, TWiV 1211, TWiV 1215, TWiV 1217, TWiV 1219, TWiV 1221, TWiV 1223, TWiV 1225, TWiV 1227, TWiV 1231, TWiV 1233, TWiV 1241, TWiV 1243, TWiV 1245, TWiV 1285. Herpesviruses and dementia TWiV 1187, TWiV 1207, TWiV 1249, TWiV 1263, TWIV 1233 Hepatitis B, C TWiV 1213, TWIV 1237, Chari Cohen, Stephan Urban, Thomas Tu, TWiV 1279 POTW themes/highlights Dickson Despommier passes TWIV 1195, TWiP 254, YouTube excerpt, DDD Photography, 'Despommier's Parasitic Diseases' H5N1 in dairy cattle TWiV 1193, TWiV 1257, TWiV 1259 (goats), TWiV 1211 EBV and Lupus TWiV 1273 Vaccines TWiV 1209, TWiV 1265, TWiV 1267 Some classic papers TWIV 1241, TWiV 1273, TWiV 1275, TWiV 1279, TWiV 1269 Respiratory infections awaken dormant breast cancer cells TWiV 1243 Phages TWiV 1261, TWiV 1181 Letters read on TWiV 1285 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Kathy – APOD for 1/1/2026; American Kestrals Put the Cherry on Top Primary article (open access) Vincent – Science in Your Own Back Yard by Elizabeth Cooper Listener Picks Bill – They did the Monster Slash and Elle Cordova Rona – The married scientists torn apart by a COVID bioweapon theory Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Dr. Peter McCullough walks through what he's seeing clinically — patients years out from COVID or vaccination who are still dealing with clotting issues, neurologic symptoms, immune dysregulation, mast cell activation, and unexplained decline. Not rare cases. Everyday people. Many of them functional — until they weren't.We talk about why Long COVID isn't always a new condition, but often the thing that pushes underlying vulnerabilities into the open. Genetic predispositions. Autoimmune tendencies. Histamine intolerance. Microvascular injury. Things that were once quiet suddenly aren't.May shares her own experience from the patient side — navigating worsening symptoms, being told it was hormones, stress, or anxiety, and eventually realizing the timeline didn't lie. The labs didn't either.Dr. McCullough explains why antibody levels matter, why spike protein itself is rarely measured, and why chasing secondary diagnoses (Lyme, mold, EBV, heavy metals) often leads people in circles without addressing the root issue.This isn't a protocol episode.It's not reassurance.And it's not abstract.It's a direct conversation about ongoing biological injury, what's being missed, and why so many people feel like their bodies changed — and never fully came back.If you've felt stuck in that in-between space — not sick enough for answers, not well enough to live normally — this episode speaks to exactly that gap.Guest Bio: Dr. Peter McCulloughDr. Peter McCullough is a practicing cardiologist, internist, and clinical researcher with decades of experience in cardiovascular medicine and academic publishing. He has served on the faculties of multiple medical schools, contributed to hundreds of peer-reviewed publications, and has been deeply involved in clinical research, outcomes analysis, and patient care throughout his career.Since the COVID era began, Dr. McCullough has focused extensively on understanding post-infection and post-vaccination complications, including myocarditis, thrombosis, immune dysregulation, and Long COVID–related syndromes. He continues to treat patients clinically while examining emerging data on persistent spike protein, inflammatory injury, and recovery patterns that fall outside traditional medical frameworks.Known for his willingness to question prevailing narratives and follow the data where it leads, Dr. McCullough remains a polarizing but influential voice in ongoing discussions about public health, patient safety, and the long-term consequences of pandemic-era medical decisions.Join this important mission: www.mcculloughfnd.org GET SOCIAL WITH US!
At the age of 14, Michaela Janssen Pohl became a caregiver for her mother, who lives with MS. I think most of us can agree that just being a teenager carries with it more than enough challenges. Those adolescent years are the years when just about everything in life starts changing. Imagine adding the responsibilities of being a caregiver to all the other things going on in a 14-year-old girl's life. Michaela joins me this week to explain how she found ways to survive and thrive in what can only be described as a challenging situation for any teenager. We'll also explain why you might want to think a little differently about Giving Tuesday this year. We're sharing all the details about the Phase 2 clinical trial focusing on Moderna's investigational Epstein-Barr vaccine and MS (and we'll explain why that might turn out to be important!) We're talking about how MS impacts women's health issues with this year's winner of the Rachel Horne Prize for Women's Research in Multiple Sclerosis, Dr. Kristen Krysko. And we're sharing the results of the Phase 2 clinical trial for PIPE-307, an investigational remyelination therapy. We have a lot to talk about! Are you ready for RealTalk MS??! It's Giving Tuesday (and why that matters more this year than ever before) :22 This Week: Becoming a caregiver for a parent with MS when you're 14 years old 3:27 A clinical trial focused on an EBV vaccine and MS is recruiting participants 4:25 Dr. Kristen Krysko discusses MS and women's health issues 7:52 Results from the Phase 2 clinical trial for PIPE-307 remyelination therapy 13:48 Michaela Janssen Pohl shares her story of becoming a caregiver at the age of 14 16:55 Share this episode 33:20 Next week's episode 33:40 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/431 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com DONATE: The National MS Society https://nationalmssociety.org/donate SIGN UP: Become an MS Activist https://nationalmssociety.org/advocacy PARTICIPATE: Phase 2 Clinical Trial for Moderna's EBV Vaccine and MS https://clinicaltrials.gov/study/NCT06735248 Email: WeCareClinicalTrials@modernatx.com JOIN: The RealTalk MS Facebook Group https://facebook.com/groups/realtalkms REVIEW: Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 431 Guests: Dr. Kristen Krysko, Michaela Janssen Pohl Privacy Policy
Could a past virus be the missing link behind your Hashimoto's? In this episode of Paloma's My Thyroid Health podcast, we unravel the hidden connection between viral infections and Hashimoto's thyroiditis — and what that means for your health.Join Paloma Health as we explore:How your immune system's fight against a virus can backfire, triggering an autoimmune attack on your thyroid through a phenomenon called molecular mimicry. The surprising way certain viruses—like EBV, CMV, enteroviruses, and even COVID-19—may directly infect thyroid cells, fueling chronic inflammation and autoimmune flares. Why some viral infections lie dormant only to reawaken later, reactivating your immune system and worsening thyroid autoimmunity. Real-world strategies for supporting your thyroid when viral triggers are involved: immune resilience, monitoring, and balancing inflammation. If you've ever wondered why your Hashimoto's symptoms flare, or felt like your thyroid health has chronically “off” sessions — this episode shines a light on a lesser-known piece of the puzzle.
If you're wondering which therapies may influence care delivery, budgets, and decision making in 2026, the pipeline offers an early preview and it points to a year defined by innovation. We're seeing new first in class treatments, thoughtful next generation agents, and a biosimilar market where fewer launches are offset by important competitive shifts driven by recent approvals. John Schoen and Heather Pace from the Center for Pharmacy Practice Excellence join Stacy Lauderdale, Associate Vice President of Evidence-Based Medicine and Drug Information and your Verified RX program host to highlight pipeline agents worth watching and discuss what they may mean for care delivery and spend management in the year ahead. Guest speakers: John Schoen, PharmD, BCPS Senior Clinical Manager of Drug Information Vizient Center for Pharmacy Practice Excellence Heather Pace, PharmD Senior Clinical Manager of Drug Information Vizient Center for Pharmacy Practice Excellence Host: Stacy Lauderdale, PharmD, BCPS Associate Vice President Vizient Center for Pharmacy Practice Excellence Show Notes: 01:01 — Episode Scope The focus is non-CGT therapies; CGT pipeline will be covered in Part 2. 01:50 — Therapeutic Areas With the Most Approvals Oncology leads the pipeline. Others include infectious disease, neurology, rare disease, endocrine, hepatology, dermatology, and rheumatology. 02:37 — Biosimilars in 2026: Momentum or Headwinds? Discussion of potential “biosimilar void”—only 10% of expiring biologic patents have biosimilars in development. Emerging role of PBM private-label biosimilars. 03:51 — FDA Draft Guidance on Interchangeability FDA exploring interchangeable designation for all biosimilars. Potential shift away from clinical efficacy studies in favor of analytical comparisons. Guidance still in draft and open for public comment. 05:34 — John's Top Picks for First-in-Class Agents 06:11 — Orviglance First manganese-based, oral MRI contrast agent. Advantages for patients with kidney impairment. Used for liver imaging. 06:20 — Why Non-Gadolinium Matters Lower risk of nephrogenic systemic fibrosis. 06:46 — Tabelecleucel First allogeneic EBV-specific T-cell therapy. For EBV-positive PTLD post-transplant. Could become new standard of care. 07:42 — Tanruprubart First therapy specifically for severe Guillain-Barré Syndrome (GBS). Shows improved outcomes over IVIG and plasma exchange. 08:20 — Comparing to Standard of Care Review of improved real-world data outcomes. 09:03 — Therapies That May Shift Care Delivery 09:32 — Icotrokinra: First oral IL-23 antagonist for plaque psoriasis. 10:00 — Insulin Icodec First once-weekly basal insulin for type 2 diabetes. Resubmitted after safety concerns in type 1 diabetes. 10:59 — Honorable Mentions Camizestrant SERD for ER+/HER2– metastatic breast cancer. Ensitrelvir (COVID-19) Oral option for pre-exposure prophylaxis. Also being evaluated for treatment. Doravirine + Islatravir (HIV) Introduces new NRTTI class. Cefepime + Zidebactam Active against metallo-β-lactamase–producing organisms. 14:05 — Key Biosimilar Launches Omalizumab (Xolair) First biosimilars in asthma/allergy space. Aflibercept (Eylea) High competition expected pending litigation. Pertuzumab (Perjeta) First biosimilar anticipated in oncology. 15:31 — Biosimilars Approved in 2025, Impacting 2026 Ustekinumab (Stelara): first full year of competition Denosumab (Prolia/Xgeva): 10–15 biosimilars expected Eculizumab (Soliris): notable for rare disease market entry 17:17 — John's Closing Thoughts Strong mix of first-in-class advances and next-gen convenience therapies. 17:36 — Heather's Closing Thoughts 2026 will focus on speed and scale after the 2025 biosimilar wave. Pharmacists pivotal in ensuring smooth patient transitions. VerifiedRx Listener Feedback Survey: We would love to hear from you - Please click here Subscribe Today! Apple Podcasts Spotify YouTube RSS Feed
Could a common virus that most of us carry be quietly fanning the flames of autoimmune disease?Scientists are uncovering an intriguing link between the Epstein-Barr virus (EBV) and conditions like lupus— suggesting this long-dormant invader might trigger the immune system to turn against itself. Let's dig into the latest research, explore how EBV hides in your body for decades, and reveal natural ways to strengthen your immune defenses and calm autoimmune flare-ups.Dr. Bob Martin and Dr. Adam Brockman answer caller questions.
Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks… Gaby: Hello Dr. Cabral, Thanks for your work you're doing! And sorry for the long question. I am a 19 year old female, and have been struggling with gut issues since I was a baby. Bloating, constipation, diarrhea, gas, nausea, and so forth. I have had functional medicine and conventional bloodwork done. My progesterone tested low and also my estrogen was low. I have the symptoms of very high androgens/testosterone, despite conventional testing showing normal levels. Been diagnosed with low cortisol/adrenal fatigue. My thyroid panels are good. I have struggled with very low B12 vitamins (maybe from not knowing that I had MTHFR). I've had severe menstrual cramps ever since getting married recently. I can't afford more testing, but am wondering how this all connects? Liz: Hi Dr. Cabral, I have a very large fluid-filled, non-malignant cyst on my thyroid. When I swallow it looks like a golf ball is in there. Doctor said it's nothing to worry about. All my thyroid labs, including antibodies, came back normal. Food sensitivity test I had a couple years ago showed dairy and eggs being a problem and they were a big part of my diet for the past couple of years until recently. Am currently in week 1 of your 21 Day Detox. My question is, is there any way to shrink or eliminate the cyst without having a procedure? Thanks! Noah: Hi Dr. Cabral, I'm 24 and recently recovered from mono, but I've been feeling exhausted ever since—almost like my body can't fully bounce back. My doctor says it's just "post-viral fatigue," but I'm wondering if there's more to it, like EBV reactivation or mitochondrial depletion. What would be your next step to rebuild energy naturally? Eleazar: Hello dr cabral i have a question about my post viral pots i have been dealing with since January of 2024 and how you would try to fix it. my question is if a viral infection which are normal and everyone gets caused this autoimmune reaction what exactly would u target to fix the autoimmunity if the virus is gone and there isnt much to remove unlike other cases of autoimmunity where a gut dysbiosis or heavy metals is causing the disease u know what to remove I hope that makes sense thank you for your time and videos u put they are very informative Eleazar: Hello dr Cabral i have another question regarding autoimmune disease i am a 21 year old male and soon i will be fixing all my root causes for my suspected autoimmune pots disease. I have completed the big 5 but my question is will i ever be able to drink alcohol again like beer for example or will it always be a risk for reactivating the autoimmune disease i see many functional medicine doctors say only 1-2 beverages but does it really have to be just that amount or can u drink more also i heard u mentioned binge drinking can cause epigenetic immune shift what exactly is that and can it be fixed and if i do drink will i need to avoid eating fast food at the same time even if its on occasion.thank you for the amazing videos u do Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3579 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
One in 4 people is infected with this silent killer disease that's deadlier than the plague. You may even have this infection! Find out about this deadly microbial threat and how to stay healthy so you don't become the next victim. 0:00 Introduction: Infectious disease deadlier than the plague 1:30 Latent infections 2:59 Tuberculosis facts 4:39 Tuberculosis and vitamin D7:38 Immune system function8:20 Sun exposure and infrared rays Many people are infected with a disease that's worse than the plague! The plague killed 200 million people, and in total, this bacterium has killed 1 billion! It's the world's deadliest infectious disease and kills more people than HIV and malaria combined. It kills around 1.3 million people each year, yet you don't hear much about it. Latent infections such as herpes, EBV, CMV, HPV, and Hepatitis B and C are able to go in and out of remission. Today, we're going to talk about the pathogen that gives you tuberculosis.Tuberculosis (TB) doesn't evade the immune system, it invades it. TB hides inside the macrophage, which is responsible for cleaning up bacteria and infections in the body. TB affects more people in the northern hemisphere away from the equator, and its incidence increases in the winter. Older people or those with type 2 diabetes, HIV, or low vitamin D are at an increased risk of an active TB infection. TB blocks the vitamin D receptor, which lowers your immune function. There was an uptick in TB outbreaks in the 80s when sun phobia was promoted. This campaign significantly reduced vitamin D levels by reducing sun exposure. Before the development of antibiotics, people with tuberculosis would go to sanatoriums for fresh air and sunlight exposure. Cod liver oil was also shown to be beneficial for people with tuberculosis infections.The immune system destroys TB with a compound called cathelicidin, a broad-spectrum antimicrobial that depends on vitamin D. Not only is the sun vital for vitamin D production, but it also exposes you to infrared light. Infrared reverses mitochondrial damage and can increase vitamin D signaling, further protecting you from a TB infection. Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.
In this episode, Evan H. Hirsch, MD, breaks down why many people with ME/CFS and long COVID continue to feel tired even after treating Epstein-Barr Virus (EBV). If you've tried antivirals, herbs, or IV treatments and still aren't better, this episode explains why that may be the case. Evan reveals how immune dysfunction, toxic overload, and the full Toxic 5, heavy metals, chemicals, molds, infections, and nervous system dysregulation, must all be addressed together for true healing. You'll also learn why lab tests often give false reassurance, and why protocols that only treat EBV tend to fail in complex chronic conditions. Watch to understand: Why Epstein-Barr is rarely the only problem How toxins impair immune function and block viral recovery What the “Toxic Matrix” is and how it keeps you stuck Why Evan's 4-step program produces real results for ME/CFS & long COVID If you've tried everything and still aren't better, this episode could change everything. . We help you resolve your Long Covid and Chronic Fatigue (ME/CFS) by finding and fixing the REAL root causes that 95% of providers miss. Learn about these causes and how we help people like you, Click Here. Do you have fatigue, brain fog, shortness of breath, muscle pain, or other strange symptoms? You might have Long Covid. Take our free quiz to find out if Long Covid is behind the mystery symptoms you're experiencing, Click Here. For more information about Evan and his program, Click Here. Prefer to watch on Youtube? Click Here. Please note that any information in this episode is for educational purposes only and does not constitute medical advice.
In this episode Dr. Motley picks Dr. Kasia Kines' brain all about an incredibly prominent but lesser-known condition, Epstein-Barr Virus! Dr. Kines - a doctor of clinical nutrition and expert on EBV - lays out for us how stress and trauma influence this virus (and how it hits empaths especially hard) as well as how simple lifestyle shifts combined with inner work can help you feel like yourself again. Show notes ⬇️ Want more of The Ancient Health Podcast? Subscribe to the YouTube channel. Follow Dr. Chris Motley Instagram Facebook Tik-Tok Website Find out more from Dr. Kasia Kines! The EBV solution https://ebvhelp.com/the-book/ Your all-EBV hub: www.ebvhelp.com EBV Recovery Program: www.ebvonlineprogram.com Social media: FB: https://www.facebook.com/kasiakinesnutritionist/ YouTube: https://www.youtube.com/channel/UCcLEIGA7b6l3WYIbiCWEGiQ Instagram: https://www.instagram.com/drkasiakines/ ------ * Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for courses full of his expertise and clinical wisdom, plus bring all your questions to his weekly lives! Try it FREE for 15 days. Join here: *If you want to work with Dr. Motley virtually, you can book a discovery call with his team here: https://drmotleyconsulting.com/schedule-1333-7607 * Charge your cells with pure antioxidant power! Liposomal supplementation has been proven deeply effective and LivOn Labs got there first. Get 10% off your liposomal supplements with code MOTLEY at livonlabs.com
Chronic illnesses are deeply intertwined with our emotions! In this episode Dr. Motley chats with Lorrie Rivers, a best-selling co-author with Deepak Chopra and Wayne Dyer, dedicated to helping individuals take control of their own health by addressing root causes of chronic conditions. Lorrie and Dr. Motley dive headlong into the ins and outs of addressing symptoms of chronic illnesses like Long Covid, how the physical and emotional influence each other, and how trauma in our genetic past can sometimes be a piece of the puzzle. Lorrie Rivers' 4 Root Causes of Chronic Illness: →Toxins →Infections: Parasites, Lyme, EBV and more →The state of our nervous system →Our environment Books Mentioned: Loving What Is by Byron Katie: https://shorturl.at/ywm6N When Things Fall Apart by Pema Chodron https://shorturl.at/ujOrG How Emotions Are Made by Lisa Feldman Barrett: https://shorturl.at/Luo3d Want more of The Ancient Health Podcast? Subscribe to the YouTube channel. ------ Follow Dr. Chris Motley Instagram Facebook Tik-Tok Website ------ Follow Lorrie Rivers! https://www.instagram.com/lorrierivers lorrieriversholistic.com ------ * If you're a health coach looking to advise parents and families, or even if you're a hardcore health nerd who wants to dive deeper and take advantage of ALL Doctor Motley's clinical experience, he has a membership to help you get the most out of your health and help the people you love. Check it out for free for 15 days: doctormotley.com/15 *If you want to work with Dr. Motley virtually, you can book a discovery call with his team here: https://drmotleyconsulting.com/schedule-1333-7607 * Enjoy mineral replenishment in a shot glass. Head to beamminerals.com/DRMOTLEY and use code DRMOTLEY for 20% off!
Vincent travels to Waterville Valley, NH to attend the Harvard virology retreat, where he speaks with Aaron Schmidt, Ben Gewurz, and Tatum Sass about their careers and their research on influenza virus, Epstein-Barr virus, and CAR-T cells. Hosts: Vincent Racaniello Guests: Aaron Schmidt, Ben Gewurz, and Tatum Sass Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Harvard Program in Virology Conserved sites on H1 and H3 HA (Sci Adv) Antigenic drift expands viral escape (Immunity) EBV LMP1 drives B cell oncometabolism (PLoS Path) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions: Leah: Hi, I was wondering if you know about how to deal with constipation and stuck poop due to tortuous colon. Thank you! Bettina: Dear Dr. Cabral, I'm reaching out regarding my husband, who is 47 years old and experiencing a range of symptoms that we're hoping to better understand. He has sensitive gums that are gradually receding, and he produces an excessive amount of earwax. He blows his nose daily and often feels tightness and tension in his neck, throat, and upper body. He is gluten intolerant and also reacts to milk sugar and lactose. Additionally, he frequently struggles to fall asleep. While these symptoms may not be directly related, I'd greatly appreciate your insight into any potential underlying connections or contributing factors and ideas to what my husband can do to change this. Thank you very much for your time and expertise. Ellen: I have a question about high serum vitamin B12 levels. The normal range on the lab is 232 - 946. I am more than double the high end of the range at 1945. I take a daily multivitamin with with 400 mcg of B12, and take no other B12 supplement. Why is my number so high? Diana: Hi Dr. Cabral, My liver is stressed. Found out I have fatty liver in May, but am already doing everything I should to help reverse it. I'm wondering what you would do in my situation. For background, I have Ehlers Danlos & ME/CFS for 30 years (I'm 42). Have horrible PEM (can't walk for 5 mins, have to carefully plan all exertion), so can't exercise. Hypometabolic & blood glucose constantly elevated & spikes with exertion (walking to my kitchen, etc.), but eat healthy & no spikes with food. EBV reactivated 5 years ago & won't go away. Did Big 5 last year, nothing with liver came up. Have mold toxicity & SIBO, took binders to help. Did CBO protocol, but SIBO & mold won't go away. Do 21-day detox regularly, take DNS powder 2x per day + almost all supplements suggested in NAFLD podcast. Allen: I am new to your podcast but saw you are offering the First Labs Program for 50% off labs. Is this all labs like the Big 5, or only certain ones. Can I run all of them? Thanks for all your help and work you are putting out! Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions! - - - Show Notes and Resources: StephenCabral.com/3508 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Your baby's future health starts long before pregnancy—and BOTH parents play a critical role.In this empowering interview, Dr. Michael Karlfeldt reveals how nutrition, detoxification, and lifestyle choices in the pre-conception phase can shape not just your baby's health at birth, but their lifelong well-being.Dr. Michael Karlfeldt, ND, PhD, is a leader in integrative medicine and founder of The Karlfeldt Center in Boise, Idaho, where he has supported health transformations since 1987. He is the author of A Better Way to Treat Cancer, host of True Health: Body, Mind, Spirit on Tubi TV, and creator of HealthMade Radio, where he engages with global wellness experts. Dr. Karlfeldt is widely recognized for his patient-centered, holistic approach to cancer, Lyme disease, and chronic health conditions, blending physical, emotional, nutritional, and spiritual care to harness the body's natural healing power.From fertility nutrition essentials to practical detox strategies, you'll learn how to prepare your body—and your partner's—for conception, pregnancy, and postpartum recovery.
I'm obsessed with this conversation. Hali Laricey taught me how to read my CBC with differential like a detective - and you probably already have years of these sitting in your patient portal right now. Those "normal" labs everyone dismisses? They're actually hiding specific patterns that can predict autoimmune flares months before symptoms hit. Hali breaks down the exact functional ranges for neutrophils, lymphocytes, and monocytes that reveal bacterial loads, viral activity, and chronic infections like EBV. This isn't about ordering expensive specialty tests - the CBC with differential is available anywhere and costs almost nothing. If you've been told your labs are normal but you still feel terrible, this episode will give you the tools to have empowered conversations with your healthcare team.For the full show notes, links and transcript visit inspiredliving.show/207
Tracy Ross, MEd, RDH, explores the nature of the Epstein-Barr virus (EBV), revealing some of its diseases, outlining the relation to periodontal and oral conditions, and discussing the current state of vaccination efforts. Read by Jackie Sanders https://www.rdhmag.com/pathology/oral-systemic/article/55293102/the-complex-epstein-barr-virus-understanding-its-systemic-impact-and-oral-implications
In our conversation, Dr Akhave discussed the addition of toripalimab (Loqtorzi), a PD-1 inhibitor, to the NCCN Guidelines following its launch in the United States. Supported by data from the phase 3 JUPITER-02 trial (NCT03581786), toripalimab is now incorporated into frontline therapy for patients with recurrent metastatic or de novo metastatic Epstein–Barr virus (EBV)–positive NPC, in combination with gemcitabine and cisplatin. He explained how this regimen has produced substantial improvements in progression-free survival (PFS), nearly tripling median PFS compared with chemotherapy alone, while maintaining a manageable safety profile.
If you've been told your labs are “normal” but you know something is wrong, this episode is for you. Dr. Josh Axe sits down with ancient medicine expert and practitioner Dr. Chris Motley to uncover how stealth infections like Lyme, mold, EBV, and parasites may be secretly driving thyroid issues, fatigue, and autoimmune flare-ups. They explore why so many women are dismissed in traditional medicine, how Chinese medicine views the thyroid, and the herbs that truly support lasting healing. In this episode, you'll learn: Signs you may have hidden infections like mold or parasites Why chronic infections trigger thyroid and autoimmune issues How to tell if your “normal” labs are missing something critical Top nutrients thyroid patients are missing The most overlooked causes of Hashimoto's and hormone imbalances Herbs that clear viruses, support immunity, and heal terrain #DrJoshAxe #DrMotley #LymesDisease #EBV #Parasites #Mold #Autoimmune __________ The Dr. Bill Rawls' interview will be airing soon! Make sure to subscribe and hit the notification bell so you don't miss out… Subscribe to the YouTube channel. ___________ Follow Dr. Josh Axe Instagram X Facebook TikTok Website Follow Dr. Chris Motley Instagram X Facebook _________ Staying healthy in today's world is an upstream battle. Subscribe to Wellness Weekly, your 5-minute dose of sound health advice to help you grow physically, mentally, and spiritually. Every Wednesday, you'll get: Holistic health news & life-hacks from a biblical world view Powerful free resources including classes, Q&As, and guides from Dr. Axe The latest episodes of The Dr. Josh Axe Show Submit your questions via voice memo to be featured on the show → speakpipe.com/drjoshaxe _________ Ads: At MyBloodwork.com, you can uncover what's really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism. You'll also get a 1-hour consultation with a Senior Health Advisor to help you take action. Learn more about your ad choices. Visit megaphone.fm/adchoices
Agenda: 1. What is Lyme Disease? What are the co-infections? 2. What is special or unique about these infections' vs any other infection, like the common cold? 3. Talk to us about the testing for these organisms. Why is it so confusing? Is there actually accurate testing?a. Borrelia: FISH for all (but not available for all) but for: borrelia, borrelia genus for cousins, TBRF borrelia myomoti, hermensi, found in other regionsb. Babesi: FISH with all the strains or just otocolic. Bartonella henselae: FISH. At least 46-48 species, 13 can infect humans, only bits of testing. d. T-Lab for FISH. Igenex also does some FISH testing. e. To fill other holes: Vibrant TBP, Galaxy specific for bartonella4. Talk to us about treatment. Let's start with antibiotics & then move outwards- what's the approach here with antibiotics? a. Are antibiotics always needed? b. Do anti-viral for anti-fungal have a role here? c. What about ancillary treatments like disulfiram? Are there others like this? d. What about mitochondrial supports, detox, and binders? e. What about nutritional supports? f. What about diet, lifestyle & the mind? 5. Where does chronic Lyme sit in the pantheon of other chronic infections like Long-COVID & EBV & Strep with PANS/ PANDAS? How much does treatment overlap for these diseases? 6. How much do environment (personal microbiome, community, environmental toxicity) & genetics contribute to the risk for developing or persisting chronic infections? How do you best like to assess or treat this? 7. Let's talk politics for a moment: Why won't many conventional clinicians recognize or treat chronic Lyme? 8. What's up & coming in the Lyme world research & education-wise? Tell us about ILADS! 9. Where can folks find you & more about your practice? https://drtaniadempsey.com/Bio: Dr. Tania Dempsey, MD, ABIHM is a world-renowned expert in complex, multisystem diseases. As founder of the AIM Center of Personalized Medicine, in Purchase, NY, Dr. Dempsey uses functional and integrative medicine to get to the root cause(s) of illness and to help find the path to optimum health. Her extensive knowledge and experience with Mast Cell Activation Syndrome, Mold, and Lyme and other Vector-Borne Diseases, has propelled her to the forefront of the medical community as a recognized and trusted speaker, researcher, advocate, and physician. Dr. Dempsey is Board-Certified in Internal Medicine and Integrative and Holistic Medicine. She received her MD degree from The Johns Hopkins University School of Medicine and her BS degree from Cornell University. She completed her Internal Medicine Residency at NYU Medical Center. She was recently elected to the Board of Directors of ILADS (International Lyme and Associated Diseases Society). She is also a member of the U.S. ME/CFS Clinician Coalition, the American Academy of Ozonotherapy, and ISSWSH (International Society for the Study of Women's Sexual Health). She is an accomplished international speaker, writer and thought leader and has 8 peer-reviewed articles in the medical literature. Her latest endeavor is cohosting the new podcast, Mast Cell Matters. At the heart of Dr. Dempsey's work is a commitment to patients who've long gone unheard.
Epstein-Barr virus is nearly ubiquitous, yet its clinical implications in women's health, fertility, and immunity are often overlooked. Uncover the latest insights and practical strategies to spot, manage, and explain chronic viral reactivation and its ripple effects on vibrant wellness.Today on The Vibrant Wellness podcast Dr. Emmie Brown, ND, and Melissa Gentile, INHC, welcome Dr. Katie Zaremba, a functional medicine and fertility specialist, to unpack the evolving science behind Epstein-Barr virus (EBV) and its clinical intersections with fertility, autoimmunity, and hormone health. Dr. Zaremba brings her expertise on chronic infections, sharing a rich overview of EBV's prevalence and its varied clinical presentation, from acute “kissing disease” fatigue in adolescents to subtle, lingering symptoms in adults that often evade routine clinical detection.Hit play and gain targeted advice for assessing, explaining, and managing chronic viral load, including practical, nutrient-focused recommendations for immune support, stepwise lifestyle interventions, and the importance of stress reduction for optimizing patient outcomes and fertility. Dr. Zaremba's practical analogies, evidence-informed protocols, and patient advocacy offer clinicians actionable tools for elevating women's health and advancing vibrant wellness.Key Takeaways from Today's Episode:
Could vagus nerve toxicity be the hidden root of your fatigue, brain fog, and poor recovery? In this powerful episode of The Coach Debbie Potts Show, I sit down with bestselling author, award-winning journalist, and founder of Vibrant Blue Oils—Jodi Sternoff Cohen—to explore how toxins, infections, and trauma can impair the vagus nerve and shut down your parasympathetic “rest and digest” system. We discuss: What is vagus nerve toxicity—and how to identify it Root causes like mold, EBV, Lyme, trauma, and EMFs How vagus nerve dysfunction blocks detox, digestion, and healing How essential oils can retrain your nervous system Jodi's favorite oils to support vagal tone, lymph flow, fascia release, and more
In this episode of the Root Cause Medicine Podcast, Dr. Kate Kresge sits down with functional immunology expert and educator Dr. Samuel Yanuck to explore one of the most overlooked systems in chronic illness: the immune system. With clarity and compassion, Dr. Yanuck breaks down how immune dysregulation can contribute to complex conditions like depression, neuropathy, migraines, chronic fatigue, and even cardiovascular disease. From brain inflammation and mast cell activation to Epstein-Barr virus and mold, Dr. Yanuck offers a new way of thinking about biology—where inflammation isn't just a symptom, but a system that can be measured, understood, and treated. You'll here them discuss: - Why immunology could be at the root of nearly every chronic illness - The immune pathways that connect depression, anxiety, brain fog, and fatigue - What PANS, PANDAS, and autoimmune encephalitis really are—and why they're often misdiagnosed - How gut, brain, and immune health form a feedback loop - The labs you should run if you suspect chronic immune dysfunction - A framework for evaluating chronic viral infections like EBV and CMV - Natural immune modulators: Chinese skullcap, astragalus, quercetin, sulforaphane, and more - Why personalized immune workups—not protocols—create results Guest Bio: Dr. Samuel Yanuck is a functional medicine clinician and expert educator in functional immunology. He is the creator of Cogence Immunology, a comprehensive online training program that has educated over 9,000 clinicians in over 60 countries. His approach blends immunology, clinical experience, and systems thinking to help providers and patients uncover the true drivers of chronic illness. Dr. Yanuck is also the co-founder of the Yanuck Center for Life and Health in North Carolina, where he sees patients and helps clinicians find root-cause solutions to immune dysfunction through mentorship and collaboration. His work is helping reshape how the next generation of practitioners understand inflammation, autoimmunity, and healing. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide
Are you struggling with unexplained allergic reactions, chronic inflammation, rashes, fatigue, anxiety, or gut issues? You may be dealing with Mast Cell Activation Syndrome (MCAS)—a complex and often misunderstood immune system condition.In this episode of Root Cause Radio, functional medicine dietitian and hormone specialist Lacey Dunn and Anya Rosen dive deep into:What is MCAS and how it differs from histamine intoleranceCommon MCAS symptoms like hives, flushing, brain fog, IBS, POTS, and moreKey root causes including mold toxicity, chronic infections (like Lyme or EBV), SIBO, stress, and traumaHow to identify triggers and reduce mast cell degranulationThe best natural supplements and low-histamine diet tips to stabilize mast cellsHow to start to address gut health, detox , and nervous system dysregulationHere is a time-stamped outline of the key points discussed in the meeting, organized by minutes:0-1 minute: Introduction to the topic of mast cell activation syndrome (MCAS)1-2 minutes: Anya discusses the increasing prevalence of MCAS diagnoses and the differences between histamine intolerance and MCAS2-3 minutes: Lacey defines what mast cells are and how MCAS develops, as well as the differences between histamine intolerance and MCAS3-5 minutes: Lacey outlines the wide range of MCAS symptoms across different body systems5-7 minutes: Anya discusses the diagnostic criteria for MCAS7-8 minutes: Lacey and Anya discuss mold as a common root cause for MCAS8-9 minutes: Lacey identifies other potential root causes like infections, GI issues, genetics, and trauma/stress9-10 minutes: Anya emphasizes the importance of stabilizing the nervous system before addressing root causes10-12 minutes: Lacey and Anya recommend various natural supplements and medications for MCAS management12-13 minutes: Lacey cautions about potential side effects of certain supplements like quercetin13-15 minutes: Anya and Lacey discuss the role of lifestyle factors like reducing toxic exposures15-17 minutes: Lacey notes connections between MCAS, POTS, and Ehlers-Danlos Syndrome, and advises against what can hold you back from healing17-18 minutes: Lacey and Anya wrap up and encourage listeners to reach out for supportIdentifying root causes beyond just mold @ 15:07Emphasizing stabilizing the nervous system first @ 16:40Discussing connections to other conditions like POTS and EDS @ 30:09Need one on one help?Lacey's info:My Website & Work with Me: Instagram: www.instagram.com/faithandfitwww.upliftfitnutrition.comEmail for coaching & phone consults: laceydunn@upliftfitnutrition.com & fitandfaith@gmail.comMy Supplement Company:Order my book "The Women's Guide to Hormonal Harmony" on amazon! Anya Rosen's info:Website: Instagram: Email: anya@birchwell.clinic
In this interview, Christie Uipi, LCSW, sits down with world-renowned mindbody physician Dr. Howard Schubiner to explore the limitations of the traditional medical model in treating conditions like POTS, Ehlers-Danlos syndrome, chronic Lyme disease, Epstein-Barr virus (EBV), mast cell activation syndrome (MCAS), ME/CFS, and Long COVID. Together, they discuss how a mindbody approach can bring clarity to these often confusing conditions - and offer a hopeful path forward for those seeking relief.
In this episode, Dr. Motley dives deeper into everything EBV, how it works, its challenges to the immune system, and what you can do to fight it. Key takeaways? Find an Epstein-Barr knowledgeable practitioner and look into homeopathy! Show Notes: Dr. Kasia Kines: The Epstein Barr Virus Solution Herbals - Astragalus: https://shorturl.at/PSYTK Ashwagandha: https://shorturl.at/rG6ga Schisandra Supreme: https://shorturl.at/4SD2r DesBio Homeopathics: DesBio Homeopathics Vitamins and Nutrients: NAC, Vitamin E + C, Selenium, Zinc, Licorice ------ Want more of The Ancient Health Podcast? Subscribe! Follow Dr. Motley! Instagram Twitter Facebook Tik-Tok Website ------ * Hunting for an excellent form of magnesium? Get 10% off ONLY with this link: bioptimizers.com/drmotley and code DRMOTLEY at checkout! *Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for courses full of his expertise and clinical wisdom on every-day health concerns, plus bring all your questions to his weekly lives! Join here: https://www.doctormotley.com/store ------
Why do we sometimes feel like we're doing everything “right” but still struggle with health issues— despite following all the best wellness routines, tools, and practices? In this special re-release, Doctor Motley explores the fascinating role of our genes, especially our recessive genes, and what happens when they become reactivated. Understanding the hidden influence of your genetics may help crack your particular health code. Dr. Motley's Recomended Labs: Bacteria and Yeast: microgendx.com Parasites: parasitetesting.com Parasites: parawellnessresearch.com Heavy Metals and Toxins, Krebs Cycle: gdx.net Mold Toxins and Mold: mosaicdx.com Lyme, EBV, Viruses: vibrant-wellness.com/HomePage Lyme Disease: dnaconnexions.com Lyme and other infections: vibrant-wellness.com/HomePage Want more of The Ancient Health Podcast? Subscribe to Doctor Motley's YouTube Channel! Follow Dr. Motley! Instagram Twitter Facebook Tik-Tok Website ------ Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for courses full of his expertise and clinical wisdom on every-day health concerns, plus bring all your questions to his weekly lives! Join here: https://www.doctormotley.com/store