AIDS/HIV: Past, Present, and Future (Video)

UC San Diego professor of biology Justin Meyer, who specializes in infectious disease research presents his course The Evolution of Infectious Diseases with special attention to the SARS-CoV-2 virus, the COVID-19 disease and its pandemic spread throughout the world. In this lecture - an overview of the emergence, life-cycle, and evolution of HIV. Series: "The Evolution of Infectious Diseases with Justin Meyer" [Health and Medicine] [Science] [Show ID: 35833]

The Last Gift study aims to understand where and how HIV hides in the human body when a person with HIV is taking HIV medications. The Last Gift study tackles these aims by studying people with HIV who are terminally ill from a disease other than HIV, like cancer, ALS, or heart disease. The study follows these volunteers with regular blood draws before the person dies and then examines multiple tissues throughout their bodies after death. From these samples, investigators hope to understand how HIV remains hidden from both the person’s immune system and from current HIV therapy. Results from these studies are designed to help develop ways to clear these reservoirs with future therapies. Dr. Davey Smith, Professor of Medicine and Chief of Infectious Diseases and Global Public Health at UCSD discusses the study and its medical and ethical implications. Series: "Exploring Ethics" [Health and Medicine] [Humanities] [Show ID: 32991]

The California HIV/AIDS Research Program (CHRP) is funding the largest demonstration project of its kind in the US, to determine the acceptability, utilization, adherence, and pharmacokinetics of HIV pre-exposure prophylaxis (PrEP) medication among transgender persons to promote their health and protect their lives. As researchers, participants and healthcare providers explain here, the three CHRP-supported studies across the state use different techniques, such as providing PrEP and hormonal therapy together at a single clinic visit, offering in-depth pharmacokinetic analyses on how the two treatments interact, or creating a custom text messaging app to communicate with providers and offer peer support. Information on how to enroll in the University of California-affiliated studies is included. Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 33176]

Dr. Paul Volberding, professor of medicine at UCSF, was perhaps the leading clinician in the United States in the early days of the HIV epidemic. As a young oncologist finishing his training in the early 1980's, Volberding recalls seeing a young gay man with a previously rare tumor: Kaposi's sarcoma. Little did he know that the underlying immunodeficiency that led to KS would come to define his career. Volberding went on to become the founding chief of the AIDS division at San Francisco General Hospital, where he established the first inpatient AIDS wards and outpatient AIDS clinic. In this interview with Dr. Bob Wachter, chair of UCSF's Department of Medicine, Volberding recalls the early days, including the impact of activism and the fear that he and other clinicians would contract the illness. He also discusses the remarkable progress in turning HIV into a manageable chronic disease and the possibility of finding a cure for AIDS.  Series: "A Life in Medicine: People Shaping Healthcare Today" [Health and Medicine] [Business] [Show ID: 32873]

UCSF Professor Emeritus Dr. Mark Jacobson is interviewed by Dr. Susa Coffey about his novel "Sensing Light." The book focuses on the HIV/AIDS outbreak from the perspective of the medical professionals who found themselves on the front lines trying to treat this horrific new disease. From the first encounter through the decades of hard work that followed, medical science attempted to identify ways to contain and treat the illness. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 32345]

Igor Grant, MD, FRCP(C) pursues research that addresses real world behavioral problems. Studying the intersection of drugs of abuse (primarily methamphetamine) and infection, his work sheds light on the basic mechanisms of injury for people with HIV. He examines inflammation in the context of neurological disorders and measures the impact of chronic stress on Alzheimer's disease caregivers. Dr. Grant joins William Mobley, MD, PhD to discuss his life in science and his fascinating work. Series: "Brain Channel" [Health and Medicine] [Show ID: 32221]

A profile of Diane Havlir, MD and her work in ending the HIV/AIDS epidemic, from co-founding the much admired Getting to Zero consortium in San Francisco to her Sustainable East African Research on Community Health (SEARCH) study in a fishing village in Kenya. Both efforts include the three pillars that are central to stopping the epidemic – preventing HIV infection with PrEP, testing and treating people immediately upon diagnosis of HIV, and retaining people in HIV care. [Public Affairs] [Health and Medicine] [Show ID: 30496]

Sir Richard Branson joins UC San Diego’s Steffanie Strathdee, Patricia Gonzalez-Zuniga, MD, and author Jon Cohen for a discussion on the costs of criminalizing drug use on marginalized communities in Tijuana and elsewhere. Series: "HIV/SIDA: The Epidemic in Tijuana" [Public Affairs] [Health and Medicine] [Show ID: 30862]

Epidemiologist Steffanie Strathdee of UC San Diego shares stories of her global health team’s intervention efforts that have helped curb the spread of HIV and tuberculosis in Tijuana and other poor regions in the world. Series: "HIV/SIDA: The Epidemic in Tijuana" [Public Affairs] [Health and Medicine] [Show ID: 30181]

John Zaia of City of Hope describe his CIRM Disease Team grant to bring a stem cell-based HIV treatment to clinical trials. Series: "California Institute for Regenerative Medicine" [Health and Medicine] [Science] [Show ID: 25754]

HIV-related stigma and discrimination are alive and well. Despite civil rights laws and protections related to the disclosure of protected health information, people with HIV often worry about their status being disclosed and when that happens, it can cause serious harm. At the same time, exciting work is being done at UC San Diego and elsewhere to integrate HIV surveillance and clinical data to increase engagement in care. Jeffrey Crowley, a Distinguished Scholar and Program Director of the National HIV/AIDS Initiative at Georgetown Law, describes a new way of thinking about the competing impulses to protect privacy while sharing information that could lead to innovations in care. He examines existing privacy protections, explores how testing and counseling methods have shifted and how big data is impacting HIV treatment and prevention. This program is part of the Exploring Ethics series, presented by the Center for Ethics in Science and Technology. Series: "Exploring Ethics" [Health and Medicine] [Science] [Show ID: 29858]

In the first of a four-part series, UC San Diego epidemiologist Steffanie Strathdee and psychologist Tom Patterson start the story of how their research teams have traced the spread of HIV in Tijuana. It opens at a wound clinic in El Bordo, the section of the Tijuana River Canal where migrants and others shoot heroin and, in some cases, share needles. Dr. Patricia Gonzalez-Zuniga offers first aid as she and her staff recruit participants into Strathdee’s Proyecto El Cuete, a study which focuses on HIV prevention for people who inject drugs. Also featured is the inspiring Susi Leal Ricardi, an HIV-positive outreach worker who was once addicted to heroin and had lived in El Bordo. Leal overcame her addiction, has been clean for 14 years, and with the help of antiretroviral drugs, she has fully suppressed her HIV. She is now El Cuete’s “star promotora.” The HIV/SIDA series is based on the book “Tomorrow Is a Long Time.” Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 30005]

In the second of a four-part series based on “Tomorrow Is a Long Time: Tijuana’s Unchecked HIV/AIDS Epidemic,” Dr. Jose Luis Burgos guides medical students from UC San Diego and Universidad Autónoma de Baja California as they offer free health care at HFiT, the Health Frontiers in Tijuana clinic at Prevencasa. The segment also features an HIV telemedicine project that spares patients a long journey to CAPASITS, the government-run HIV/AIDS clinic across town, and the Tattoo Removal Clinic, a project led by UC San Diego’s Victoria Ojeda that helps people become more presentable to potential employers. Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 30006]

In the third of a four-part series, photographer Malcolm Linton and writer Jon Cohen tell the stories of Victor, Fernanda, Sergio, Susi, Nelly and others living with HIV who are featured in their photo essay book, “Tomorrow Is a Long Time: Tijuana’s Unchecked HIV/AIDS Epidemic.” Linton and Cohen spent two years interviewing and photographing transgender women, people who inject drugs, sex workers and men who have sex with men in Tijuana, documenting what happened to them over time. Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 30007]

In the final installment of the series based on “Tomorrow Is a Long Time: Tijuana’s Unchecked HIV/AIDS Epidemic,” writer Jon Cohen explores what it would take to end the AIDS epidemic in Tijuana by 2030, as called for by UNAIDS. Dr. Davey Smith of UC San Diego argues for aggressive, frequent HIV testing in high-risk groups and shows how cutting-edge genetic science can unravel how the virus moves through communities. Cohen explains the benefits of harm reduction strategies, such as providing clean needles and methadone to thwart HIV transmission. And, in an intervention tailored specifically to this epidemic, Steffanie Strathdee and Tom Patterson’s group at UC San Diego has begun training the Tijuana Police about HIV and urging officers to see drug addiction as a sickness, not a crime. Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 30008]

The four-part HIV/SIDA series follows UC San Diego epidemiologist Steffanie Strathdee, psychologist Tom Patterson and their binational team of doctors, researchers, medical students and outreach workers as they document the spread of HIV in Tijuana. Starting at El Bordo in the Tijuana River Canal and moving to the clinics at Prevencasa, the Las Memorias AIDS hospice and then inside the Tijuana Police Academy, this series shows their efforts to treat and prevent HIV infection among high risk groups, including people who inject drugs, sex workers, transgender women and men who have sex with men. Also featured are photographs and stories of those impacted by HIV, as portrayed by Malcolm Linton and Jon Cohen in their book, “Tomorrow Is a Long Time.” The series concludes with an assessment of what it would take to end HIV/AIDS in Tijuana. Funding for the book and series was provided by the Ford Foundation. Series: "HIV/SIDA: The Epidemic in Tijuana" [Public Affairs] [Health and Medicine] [Show ID: 30004]

Staal Vinterbo, a professor in biomedical informatics at the UC San Diego School of Medicine, shows how privacy is routinely violated online and suggests new ways to guard sensitive personal information. He also presents an example of a state-of-the-art privacy protection technique and how it could be used to inform HIV prevention efforts in San Diego. Vinterbo is presented by the Center for Ethics in Science and Technology. Series: "Exploring Ethics" [Health and Medicine] [Science] [Show ID: 29414]

Although antiretroviral therapy has dramatically extended the life of HIV infected individuals, the life-long daily regimen of pills is not a cure. The drugs' side effects lead to various complications such as increased incidence of heart disease and cancer that significantly reduces lifespans. Based on this reality, the recent isolated reports of individuals being cured of HIV infection have brought a lot of excitement as well as cautiousness. Brief presentations by a distinguished lineup of clinicians, researchers and advocates, many of whom have dedicated their life's work toward finding a cure for HIV infection, address where we are with a cure for HIV. Series: "California Institute for Regenerative Medicine" [Health and Medicine] [Show ID: 28243]

On October 1st, 2013 CIRM, the AIDS Research Institute, and the Gladstone Institutes sponsored an informative, interactive Town Hall forum on HIV cure research in San Francisco's State Building. The event included a panel discussion by a distinguished lineup of scientists, clinicians, and advocate who provided the latest news in cure research from HIV conferences, the Martin Delaney AIDS Cure Research Collaborative, the biotech industry, and the California Institute for Regenerative Medicine (CIRM). Series: "California Institute for Regenerative Medicine" [Health and Medicine] [Show ID: 28244]

Dr. Susan Little of UC San Diego School of Medicine presents her research that tracks HIV infection by rapidly obtaining genetic information from those engaged in HIV healthcare. A discussion follows on privacy protections, the risks associated with the use of these data and their potential to significantly limit HIV transmission in communities. Dr. Little is presented by the Center for Ethics in Science and Technology in San Diego. Series: "Exploring Ethics" [Health and Medicine] [Science] [Show ID: 29120]

Three global health experts - Gregg Alton JD, Executive Vice President, Gilead; Ambassador Eric Goosby MD: Global Health Science, UCSF; and Stefano Bertozzi MD PhD, Dean, School of Public Health, UC Berkeley - discuss the role and responsibilities of public and private organizations in the response to the global HIV and HCV epidemics. From policy advances to facilitate access to life saving antiretrovirals for millions of patients, to challenges in regulatory infrastructure, to the rocky path for point-of-care diagnostics and treatment monitoring technologies, to the recognition that treatment is prevention and key to any containment strategy – the lessons provided by the expansion and entrenchment of the HIV epidemic, and successes and failures in the public health response are unparalleled in the global health arena. [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 28103]

Explore the current state of global HIV/AIDS. Panelists discuss what progress has been made in fighting this global epidemic, how research findings are being translated into improved clinical outcomes, and how the Bay Area research community is working to address the questions that remain. Panelists: Eran Bendavid, Assistant Professor, Medicine, Stanford; Stefano Bertozzi, Dean, School of Public Health, UC Berkeley; Diane Havlir, Professor and Chief of the HIV/AIDS Division & Positive Health Program, UCSF; Michael Larimore, Dean, School of Veterinary Medicine, UC Davis. Paul Volberding, Director, AIDS Research Institute and Director of Research, Global Health Sciences, UCSF, moderates. Series: "UC Global Health Institute" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 27756]

A look at PrEP, a prevention strategy for people at high risk for contracting HIV. Researchers at the University of California explain how pre-exposure prophylaxis (PrEP) works as they describe a four-year, multi-pronged study of men who have sex with men in Los Angeles and San Diego. Participants agree to take a Truvada pill daily to reduce their risk of getting infected by up to 99%. But will they follow through? Methods to increase adherence among the participants are also being tested, including daily reminders via text messages and tracking usage of the medication with special “Mems caps” for the pill bottles. [Public Affairs] [Health and Medicine] [Show ID: 25594]

Peter Stock, MD, PhD discusses current treatments for transplant patients with HIV. Series: "UCSF Transplant Update" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 27703]

In the final installment of a four-part series, UC Irvine Public Health professor Brandon Brown and others help members of Lima's gay and transgender community overcome the stigma of HIV and get access to healthcare. This is no small feat in Peru, long considered the most homophobic country in South America. This outreach program is part of UCI's Global Health Research, Education and Translation (GHREAT) Initiative. Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 25898]

Dr. Peter Hunt on the immunology of HIV and Dr. Steven Deeks explores if an HIV cure is achievable. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 25129]

Dr. George Beatty on HIV medications and Dr. Annie Luetkemeyer the current revolution in Hepatitis C treatment. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 25128]

Dr. Monica Gandhi addresses the differences in treating men and women; Dr. Deborah Cohan discusses conceiving (or not) in the 21st century; and Dr. Theodore Ruel discusses children and HIV. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 25127]

Dr. Jay Levyan, an AIDS and cancer researcher at UCSF, discusses the discovery of HIV and its basic science. Then, Dr. C. Bradley Hare, Associate Professor of Clinical Medicine and Medical Director, UCSF HIV/AIDS Division at San Francisco General Hospital, explores HIV and its diseases through case presentations from the clinic. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 25125]

Dr. Diane V. Havlir explores HIV, economics and global health and Dr. Oliver Bacon explores a new HIV prevention method called PrEP, in which people who do not have HIV take a daily pill to reduce their risk of becoming infected. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 25126]

Dr. Monica Gandhi, UCSF Division of HIV/AIDS, explains how and when HIV entered the human population and its current prevalence. Then Dr. Paul A. Volberding traces the history of HIV in San Francisco and current epidemiology of the disease. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 25124]

Roger Detels, Distinguished Professor of Epidemiology and Infectious Diseases at UCLA, discusses the work of the Multicenter AIDS Cohort Study and the process of studying as well as preventing HIV infections. Series: "UCLA Faculty Research Lectures" [Health and Medicine] [Show ID: 24887]

in a timely consideration of the pandemic, Spirit of Uganda executive director Alexis Hefley joins UC Davis faculty member Moradwun Adejunmobi and others in examining HIV/AIDS from the global, cultural and medical perspectives. Series: "Mondavi Center Presents" [Health and Medicine] [Humanities] [Show ID: 14230]

James Curran, MD, MPH, Emory University, presents on Reflections of the First 50 Years of the AIDS Epidemic. Series: "CFAR, UCSD Center for AIDS Research " [Health and Medicine] [Show ID: 13717]

The UCSD Center for AIDS Research (CFAR) presents a series of lectures from international experts on the latest worldwide HIV research. In this program, James Hakim, M.D., Professor of Medicine and Chair, Department of Medicine, University of Zimbabwe discusses AIDS in Zimbabwe, a microcosm of the HIV epidemic in sub-Saharan Africa. Series: "CFAR, UCSD Center for AIDS Research " [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 12277]

The UCSD Center for AIDS Research (CFAR) presents a series of lectures from international experts on the latest worldwide HIV research. In this program, Jean William Pape, M.D., Director of GHESKIO (the largest health care organization in Haiti), discusses 25 years of AIDS in Haiti. Special focus is placed on research as a key to improving medical care in resource limited settings. In addition to his work at GHESKIO, Dr. Pape is a Professor of Medicine at Cornell and a member of the Institute of Medicine. Series: "CFAR, UCSD Center for AIDS Research " [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 12276]

Did you know that in the U.S. more than 1,000,000 adults and children are living with all stages of HIV disease? In San Diego County alone, an estimated 14,000 people have this virus. Join Douglas Richman, M.D. and a panel of leading medical experts as they report back to the community on the latest developments in the battle against AIDS and HIV. Where are we now? What is the latest research? What are the hopes for the future? [Public Affairs] [Health and Medicine] [Show ID: 12010]

The current AIDS epidemic shows no sign of slowing throughout the world. With all the exciting advances currently being made in biology, can scientists come up with a cure or a vaccine to stop the spread of this deadly virus? Noted Aids researcher, Dr. Flossie Wong-Staal, UCSD delivers an analysis. Series: "40/40 Vision Lectures (UCSD Faculty Lecture Series)" [Health and Medicine] [Show ID: 5377]