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Welcome to a world where medicine meets politics: a space that brings together scientific research, government wrangling, public push-back and healthcare conspiracies…Dr Anthony Fauci was the Director of America's National Institute of Allergy and Infectious Diseases for nearly four decades, during which time he not only helped study, treat and prevent viruses such as HIV/AIDS and Covid-19; he also advised seven US Presidents, from Ronald Regan through to Joe Biden.Along the way, Tony Fauci's picked up a public profile and taken a fair amount of flack; not least because of his complicated relationship with President Donald Trump. But he's also made great strides in medical research and policy, from working with activists who initially challenged him on the government response to HIV/AIDS - to spearheading the USA's PEPFAR project to share vital medication with developing nations.In a candid conversation with Professor Jim Al-Khalili, Tony discusses his childhood in Brooklyn, the dark early days of the HIV/AIDS epidemic and lessons from the Covid-19.Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop
This week on Health Matters, we explore how to protect yourself from diseases carried by ticks and mosquitos. Dr. Jennifer Small-Saunders, an infectious disease expert with NewYork-Presbyterian and Columbia, explains why mosquitos are more attracted to some people than others. She also shares symptoms of diseases like West Nile Virus and Lyme Disease, how we can go about our summer activities without getting bitten, and what to do if you've been bitten.___Dr. Jennifer Small-Saunders is an Infectious Diseases physician-scientist who studies molecular mechanisms of antimalarial drug resistance in Plasmodium falciparum parasites. She is a practicing Infectious Diseases physician who sees patients on both the Internal Medicine and Infectious Diseases teaching services. She completed Internal Medicine residency and Infectious Diseases fellowship at Columbia University Irving Medical Center (CUIMC). Her postdoctoral studies investigated the landscape of mutations in the P. falciparum chloroquine resistance transporter PfCRT and how these mutations contribute to parasite resistance to chloroquine and piperaquine in Asia and Africa. Her group now uses mass spectrometry and gene editing techniques to study the role of tRNA modification reprogramming and translational control in resistance to the first line antimalarial, artemisinin. The goal of her group is to uncover stress-response pathways in malaria parasites that can be targeted by new treatments.___Health Matters is your weekly dose of health and wellness information, from the leading experts. Join host Courtney Allison to get news you can use in your own life. New episodes drop each Wednesday.If you are looking for practical health tips and trustworthy information from world-class doctors and medical experts you will enjoy listening to Health Matters. Health Matters was created to share stories of science, care, and wellness that are happening every day at NewYork-Presbyterian, one of the nation's most comprehensive, integrated academic healthcare systems. In keeping with NewYork-Presbyterian's long legacy of medical breakthroughs and innovation, Health Matters features the latest news, insights, and health tips from our trusted experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our renowned medical schools, Columbia and Weill Cornell Medicine. To learn more visit: https://healthmatters.nyp.org
From measles scares to shifts around COVID guidelines, vaccine conversations have gotten more complicated. Parents have questions about what's required for school, who qualifies for exemptions, and how to navigate conflicting advice from the CDC, social media, and their own doctors. The Commissioner of the Monroe County Department of Public Health joins us to cut through the noise and talk about vaccines and public health, and how her department is building trust in a time of science skepticism. In studio: Dr. Marielena Vélez de Brown, Commissioner of the Monroe County Department of Public Health Dr. Andrew Cox, associate director of Center for Infectious Disease and Immunology Research for RRH
This member-driven podcast is a benefit of membership of the Arizona Chapter of the American Academy of Pediatrics (AzAAP) and is intended for AzAAP pediatric healthcare members.AzAAP would like to acknowledge the generous support of the podcast by the Arizona Department of Health Services through the Title V Maternal and Child Health Services Block Grant funding. No information or content in this podcast is intended to substitute or replace a consultation with a healthcare provider or specialist. All non-healthcare providers should reach out to their child's pediatrician for guidance. Music: Wallpaper by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/4604-wallpaperLicense: http://creativecommons.org/licenses/by/4.0/
In episode 80 of the medical nursing podcast we're taking a long, hard look at two of the worst infectious diseases we see - parvovirus in dogs, and its not-so-distant cousin, panleukopenia virus in cats. These patients are often critically ill and need a great deal from us as nurses and technicians. In this episode, we'll explore exactly how these diseases impact our patients and the nursing care and treatment they require, so that you can care for these patients with confidence. --- Resources mentioned in this episode:
Fluoroquinolones (FQs) are valuable given their broad-spectrum activity against Gram-positive and Gram-negative bacteria and their high penetration into various tissues. Yet FQs have also caused concern, with some market withdrawals, important and sometimes long-lasting adverse drug events, and substantial collateral effects on the microbiota. In this episode of Communicable, hosts Emily McDonald and Thomas Tängdén invite Staffan Tevell (Karlstad, Sweden) and Bernadette Young (Oxford, UK) to weigh in on the pro-con debate of FQ use, especially for periprosthetic joint infections (PJIs), which can entail longer treatment durations. They review the standard of care for PJIs, including FQs in combination with rifampicin vs other antibiotic combinations, the impact of the OVIVA trial advocating for early oral switch strategies, the long list of rare but important side effects, and how best to preserve FQs for clinical indications that most need them. This episode is a follow-up from Tevell and Young's recently published systematic review of the role of FQs in PJIs [1]. It was edited by Kathryn Hostettler and peer reviewed by Ljiljana Lukić of University Hospital for Infectious Diseases in Zagreb, Croatia. The executive producer of Communicable is Angela Huttner. ReferencesTevell S, et al. To heal or harm: A systematic review of the role of fluoroquinolones in periprosthetic joint infections. CMI Communications 2025. DOI: 10.1016/j.cmicom.2025.105103Further readingMandell LA, et al. Antimicrobial Safety and Tolerability: Differences and Dilemmas. Clin Infect Dis 2001. JSTOR http://www.jstor.org/stable/4461522.Pham TDM, et al. Quinolone antibiotics. Medchemcomm 2019. DOI: 10.1039/c9md00120d. Rodrigues CF and Silva F. The Rise, Fall, and Rethink of (Fluoro)quinolones: A Quick Rundown. Pathogens 2025. DOI: 10.3390/pathogens14060525Slimings C and Riley TV. Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis. J Antimicrob Chemother 2014. DOI: 10.1093/jac/dkt477Davis JS, et al. Predictors of treatment success after periprosthetic joint infection: 24-month follow up from a multicenter prospective observational cohort study of 653 patients. Open Forum Infect Dis 2022. DOI: 10.1093/ofid/ofac048.Grossi O, et al. Gram- negative prosthetic joint infections managed according to a multidisciplinary standardized approach: risk factors for failure and outcome with and without fluoroquinolones. J Antimicrob Chemother 2016. DOI: 10.1093/jac/dkw202 Cortes-Penfield NW, et al. Adjunctive rifampin following debridement and implant retention for staphylococcal prosthetic joint infection: is it effective if not combined with a fluoroquinolone? Open Forum Infect Dis 2022. DOI: 10.1093/ofid/ofac582Pushkin R, et al. A Randomized Study Evaluating Oral Fusidic Acid (CEM-102) in Combination With Oral Rifampin Compared With Standard-of-Care Antibiotics for Treatment of Prosthetic Joint Infections: A Newly Identified Drug-Drug Interaction. Clin Infect Dis 2016. DOI: 10.1093/cid/ciw665Bock M, et al. Rifampicin reduces plasma concentration of linezolid in patients with infective endocarditis. J Antimicrob Chemother 2023. DOI: 10.1093/jac/dkad316 Zeller V, et al. Influence of the clindamycin administration route on the magnitude of clindamycin-rifampicin interaction: a prospective pharmacokinetic study. Clin Microbiol Infect. 2021. DOI: https://doi.org/10.1016/j.cmi.2021.04.017 Bernard L, et al. Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection. N Engl J Med 2021. DOI: 10.1056/NEJMoa2020198Vollmer NJ, et al. Safety and Tolerability of Fluoroquinolones in Patients with Staphylococcal Periprosthetic Joint Infections, Clin Infect Dis 2021. DOI 10.1093/cid/ciab145Gopalakrishnan C, et al. Association of fluoroquinolones with the risk of aortic aneurysm or aortic dissection. JAMA Intern Med 2020. DOI 10.1001/jamainternmed.2020.4199Li HK, et al. Oral versus Intravenous Antibiotics for Bone and Joint Infection (OVIVA). N Engl J Med. 2019. DOI: 10.1056/NEJMoa1710926
“A gentleman's hands are [always] clean” Infectious diseases caused by bacteria have killed well over half of all humans who have ever lived on Earth. Historically, bacterial infections have started major pandemics such as the bubonic plague, which is estimated to have killed 50-60 per cent of the population of Europe during the Black Death in the 14th Century. And yet when a person in Oregon came down with bubonic plague in 2024 it was a non-event. The pathogen involved was quickly identified and antibiotics given. There was no chain of infection and no epidemic. And the patient lived. Germ theory is one of the most transformative developments in human history. … Continue reading →
In this episode of The ICHE Podcast, we take a deep dive into the evolving role of plasma cell-free DNA (cfDNA) metagenomic next-generation sequencing (mNGS) in the diagnosis of infectious diseases. Hosted by experts from UCLA Health, this discussion breaks down what cfDNA mNGS is, how it differs from more traditional pathogen detection tools like PCR, and where it fits in the diagnostic landscape. Dr. Ishminder Kaur, Dr. Daniel Uslan, and Dr. Shangxin Yang join the episode to explore the clinical utility, benefits, and pitfalls of this rapidly emerging diagnostic modality. The group reviews several individual studies, highlighting how they approached their research questions, key findings, and the implications for patient care and antimicrobial stewardship. The conversation also addresses challenges such as interpreting complex results, cost considerations, and potential overuse. Whether you're a clinician, laboratorian, or infection preventionist, this episode provides critical insights into when and how cfDNA mNGS may enhance your diagnostic toolkit—and when it might not. Each guest closes with a practical takeaway: concrete advice for healthcare professionals who are considering incorporating cfDNA testing into their own clinical or infection control practice.
On episode #85 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 7/3 – 7/21/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Elimination of HIV Reservoirs Harboring Intact Proviruses (JID) Bacterial Expansion of tetM-Carrying Neisseria gonorrhoeae in the United States, 2018–2024 (NEJM) Study hints doxyPEP use coincides with rise in tetracycline-resistant gonorrhea in US (CIDRAP) Potential Impact of Doxycycline Post-Exposure Prophylaxis on Tetracycline Resistance in Neisseria gonorrhoeae and Colonization With Tetracycline-Resistant Staphylococcus aureus and Group A Streptococcus (CID) Methenamine hippurate asprophylaxis for recurrent urinary tract infections in older women – a triple-blind, randomised, placebo-controlled, phase IV trial (ImpresU). (CMI: Clinical Microbiology and Infection) Diagnosis and Management ofCommunity-acquired Pneumonia(American Journal of Respiratory and Critical Care Medicine) Complicated Urinary Tract Infections (cUTI): Clinical Guidelines for Treatment and Management (IDSA) The impact of an intervention to increase follow-up blood cultures for patients with Staphylococcus aureus bacteriuria (Antimicrobial Stewardship & Healthcare Epidemiology) Fungal The Last of US Season 2 (YouTube) Candida auris Containment Responses in Health Care Facilities that Provide Hemodialysis Services (CDC: MMWR) Candidozyma auris: an emerging threat (Reflections on Infectious Prevention and Control) Effects of postoperative antifungal therapy on the recurrence of Aspergillus infection after pulmonary aspergilloma resection (BMC Infectious Diseases) Triazole-resistant Aspergillus fumigatus in the Netherlands between 1994 and 2022: a genomic and phenotypic study (LANCET: Microbe) Large language models and their performance for the diagnosis of histoplasmosis (PLoS Neglected Tropical Diseases) Parasitic Field evidence of Trypanosoma cruzi infection, diverse host use and invasion of human dwellings by the Chagas disease vector in Florida, USA (PLoS Neglected Tropical Diseases) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
Our understanding of the human immune system today is vastly different from that of 50 years ago. This knowledge has led to immune-based therapies that would have seemed like science fiction to our grandparents: monoclonal antibodies, T-cell therapies, anti-cancer vaccines, precision immune suppression – the list is endless. In this lecture, we look to the future and ask, “What next for immunity?” This lecture was recorded by Robin May on the 11th of June 2025 at Barnard's Inn Hall, London.Robin is Gresham Professor of Physic.He is also Chief Scientific Adviser at the Food Standards Agency (FSA) and Professor of Infectious Disease at the University of Birmingham.The transcript of the lecture is available from the Gresham College website: https://www.gresham.ac.uk/watch-now/future-immunityGresham College has offered free public lectures for over 400 years, thanks to the generosity of our supporters. There are currently over 2,500 lectures free to access. We believe that everyone should have the opportunity to learn from some of the greatest minds. To support Gresham's mission, please consider making a donation: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-todayWebsite: https://gresham.ac.ukTwitter: https://twitter.com/greshamcollegeFacebook: https://facebook.com/greshamcollegeInstagram: https://instagram.com/greshamcollegeSupport Us: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-todaySupport the show
In this episode, we review the high-yield topic Pseudomonas Aeruginosa Infection from the Infectious Diseases section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode, we review the high-yield topic Dengue Fever from the Infectious Diseases section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode, we review the high-yield topic Malaria from the Infectious Diseases section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
This is the first lecture from the Gresham Festival of Musical Ideas.https://www.gresham.ac.uk/watch-now/series/musical-ideas-2025Musical instruments have been found in the archaeological record from at least 40,000 years ago and despite the diversity of human civilization, we are yet to find a culture which lacks music. Other species also make ‘music' – from a grasshopper's chirp to a nightingale's song – but is human music simply an extension of that evolutionary heritage? What can modern studies of genetics and anthropology tell us about the evolution of human musicality? Can neuroscience explain why music evokes such strong emotions? And what happens when the ‘biology of music' goes wrong?This lecture was recorded by Milton Mermikides and Robin May on 29th June 2025 at Barnard's Inn Hall, London.Robin is Gresham Professor of Physic. He is also Chief Scientific Adviser at the Food Standards Agency (FSA) and Professor of Infectious Disease at the University of Birmingham. Milton Mermikides is Gresham Professor of Music.He is Associate Professor in Music at the University of Surrey, Professor of Guitar at the Royal College of Music and Deputy Director of the International Guitar Research Centre.The transcript of the lecture is available from the Gresham College website: https://www.gresham.ac.uk/watch-now/evolution-musicGresham College has offered free public lectures for over 400 years, thanks to the generosity of our supporters. There are currently over 2,500 lectures free to access. We believe that everyone should have the opportunity to learn from some of the greatest minds. To support Gresham College's mission, please consider making a donation: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-today Website: https://gresham.ac.ukX: https://x.com/GreshamCollegeFacebook: https://facebook.com/greshamcollegeInstagram: https://instagram.com/greshamcollegeBluesky: https://bsky.app/profile/greshamcollege.bsky.social TikTok: https://www.tiktok.com/@greshamcollegeSupport Us: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-todaySupport the show
In this episode, we review the high-yield topic Legionnaires Disease from the Infectious Diseases section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
Research funded by the federal government has been crucial in many of the defining technologies of our time: the internet, A.I., crispr, Ozempic, and the mRNA vaccines first used widely in the COVID pandemic. Between 2010 and 2019, more than 350 drugs were approved in the United States, and virtually all of them could trace their roots to the National Institutes of Health (NIH). Now this administration is endangering our health by cutting funds to academic medical centers. Moreover, there are threats to Medicaid, as well as ongoing cuts to the Centers for Disease Control (CDC). Many universities have paused hiring due to the uncertainty at the NIH and are curtailing graduate programs. Biotech investors are warning of a contraction in medical innovation. NIH grants have been terminated on ideological grounds, which have resulted in clinical trials shutting down. Global health programs worldwide have been cut. A discussion on these destructive policies on medicine in our country is needed. About the Speaker Monica Gandhi M.D., M.P.H., is a professor of medicine and associate chief in the Division of HIV, Infectious Diseases, and Global Medicine at the University of California, San Francisco (UCSF). She is also the director of the UCSF Center for AIDS Research (CFAR) and the medical director of the HIV Clinic ("Ward 86") at San Francisco General Hospital. She serves as the associate program director of the ID fellowship at UCSF. Her research focuses on HIV treatment and prevention optimization, HIV and women, adherence measurement in HIV and TB, adherence interventions, and on optimizing the use of long-acting antiretroviral therapy (ART). She is a long-standing NIH-funded researcher. Commonwealth Club World Affairs of California is a nonprofit public forum; we welcome donations made during registration to support the production of our programming. A Health & Medicine Member-led Forum program. Forums and Chapters at the Club are organized and run by volunteer programmers who are members of The Commonwealth Club, and they cover a diverse range of topics. Learn more about our Forums. Commonwealth Club World Affairs is a public forum. Any views expressed in our programs are those of the speakers and not of Commonwealth Club World Affairs. OrganizerMichael Baker Learn more about your ad choices. Visit megaphone.fm/adchoices
The Clinical Microbiology Procedures Handbook (CMPH) has long been a trusted resource for laboratories. With the release of its 5th edition, this essential reference continues to guide clinical microbiologists through evolving standards, methods, and best practices. In this episode, Luis is joined by the editors‑in‑chief, Dr. Amy Leber and Dr. Carey‑Ann Burnham, to explore what's new in the latest edition, how the CMPH supports day‑to‑day work in the lab, and why it remains a cornerstone in clinical microbiology. (Originally published May 4, 2023.) Check out the website: https://www.letstalkmicro.com/ Questions? Feedback? Send those to letstalkmicro@outlook.com Want to support the podcast? Here's how: Venmo: https://venmo.com/u/letstalkmicro Buy me a Ko-fi: https://ko-fi.com/letstalkmicro
In this episode, we review the high-yield topic Candida albicans from the Infectious Diseases section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode of Tiny Show and Tell Us, we cover squirrel pox — a disease that hasn't had a huge impact in the United States but has decimated populations of squirrels in the UK. Then we talk about the story that Napoleon's army lost the Battle of Waterloo because the military uniforms used tin buttons that broke apart in cold temperatures, making it harder for the troops to survive. But is there any truth to that story? We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Peter Marks is the former director of the FDA Center for Biologics Evaluation and Research. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. P. Marks. The Role of Public Health Agencies in Creating Vaccine Policy. N Engl J Med 2025;393:209-211.
BUFFALO, NY - July 16, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on July 9, 2025, titled “A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment.” In this study, researchers from the National Institute of Allergy and Infectious Diseases, led by first author Maja Buszko and corresponding author Ethan M. Shevach, discovered a new monoclonal antibody that selectively targets a subset of immune cells called regulatory T cells (Tregs). These cells, while normally important for preventing autoimmunity, also can block the body's ability to fight cancer by suppressing anti-tumor immune responses. This discovery could lead to novel cancer therapies that strengthen the immune system's capacity to attack tumors. The researchers identified an anti-CD25 monoclonal antibody with several atypical properties and named it 2B010. To evaluate its effects, they used humanized mice, laboratory mice that are engineered to carry human immune cells, to closely mimic how human immune systems respond to cancer. The treatment of these mouse models with 2B010 significantly decreased the number of Tregs in tumors and boosted the activity of CD8+ T cells, which are essential for killing cancer cells. Importantly, 2B010 worked without disrupting other key immune functions. Unlike traditional Anti-CD25 antibodies, it did not interfere with interleukin-2 (IL-2) signaling, which is essential for the growth and activity of effector T cells that fight cancer. “2B010 also had no effect on IL-2 induced STAT5 phosphorylation or CD4+ T cell proliferation in vitro while both were blocked by Clone D1 further supporting the view that 2B010 does not recognize the IL-2 binding site.” This finding is especially significant because high levels of Tregs in tumors are associated with poor outcomes in many cancers. By specifically removing these cells, 2B010 may help overcome one of the main barriers to current immunotherapy approaches. Its ability to preserve IL-2 signaling could also make it safer and more effective when used alone or in combination with existing therapies such as immune checkpoint inhibitors. While the 2B010 antibody showed strong effects in reducing Tregs and boosting immune cell activity, the study did not observe changes in tumor size in these models. Researchers suggest this may be due to limitations in the preclinical systems used, such as the lack of tumor-specific T cells in humanized mice. Nevertheless, these findings demonstrate that 2B010 has a unique mechanism of action that could complement other cancer immunotherapies in future clinical trials. In conclusion, the development of 2B010 is a promising step toward selectively disrupting the immune suppressive environment in tumors. As researchers continue to refine and test this antibody, it could become a powerful tool for enhancing the effectiveness of cancer treatments and improving outcomes for patients. DOI - https://doi.org/10.18632/oncotarget.28752 Correspondence to - Ethan M. Shevach - eshevach@Niaid.NIH.gov Video short - https://www.youtube.com/watch?v=2NJcGsI7WXA Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28752 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, Treg, CD25, TME, mAb, GVHD To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
In this episode, we review the high-yield topic Rabies from the Infectious Diseases section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
Our guest for this week is Sara Olson. Sara (her TikTok name is SKEEETAH) is from the Wolf River area of Wisconsin which just happens to hold the highest concentration of the fungus that causes Blastomycosis. When Sara got Blastomycosis in January 2024, she thought it was 'just the flu'. With a chest xray, she was diagnosed with pneumonia. Several rounds of antibiotics didn't help so she did a CT scan where they found an embolism. Still not knowing anything else, they continued treating her for bacterial pneumonia. They did a swab of her sputum in which her health providers found no bacterial growth, but there was fungal growth. "For some reason they didn't do fungal testing" she was admitted, released and readmitted all the while she was being treated for bacterial pneumonia. The final hospitalization had her O2 levels drop to 30 and she was intubated, her family was called to come and say their goodbyes... You'll have to listen to the interview to learn more. She is lucky to be alive! Blastomycosis is a fungal infection and was linked to the Little Wolf River in Waupaca County, Wisconsin, during a summer 2015 outbreak. People who went tubing on the river were exposed to the fungus, with 59 confirmed and 39 probable cases reported according to the Wisconsin Department of Health Services (W-DHS). The fungus, Blastomyces, lives in soil and decaying organic matter, and its spores can become airborne when disturbed. Inhaling these spores can cause blastomycosis, a disease primarily affecting the lungs, though it can spread to other parts of the body. While most blastomycosis cases are sporadic, this outbreak highlighted the need for awareness about this preventable cause of illness. Key Details about the Outbreak: Cause: The outbreak was attributed to the fungus Blastomyces, which is commonly found in soil and decaying matter. Exposure: People who participated in river tubing on the Little Wolf River were exposed to the fungus. Symptoms: Blastomycosis can cause flu-like symptoms, such as fever, cough, muscle aches, and fatigue, but it can also lead to serious health problems if not treated. Transmission: The infection is not spread from person to person. Treatment: Blastomycosis can be treated with antifungal medications. Outbreak Scale: This outbreak was one of the largest in recent Wisconsin history, with 59 confirmed and 39 probable cases. Prevention: Awareness of the potential for infection is key, especially in areas where the fungus is known to be present. Additional Information: Endemic Area: Blastomycosis is endemic in the Ohio and Mississippi River valleys, the Great Lakes region, and the southeastern United States according to the CDC. Symptoms: Common symptoms include cough, fever, chest pain, fatigue, and skin sores. Risk Factors: Individuals with weakened immune systems or chronic illnesses may be more susceptible to severe illness. Not Limited to the Wolf River: While the Little Wolf River outbreak was significant, blastomycosis can occur in other areas with suitable environmental conditions. Blastomyces lives in moist soil in parts of North America. It's too small to see, so you can breathe it into your lungs without knowing it. There, it can grow and make you sick. It sometimes spreads to your skin or other parts of your body. It's hard to avoid breathing in Blastomyces fungus if you live in an area where it's common. While not entirely preventable, there are some steps you can take to reduce your risk of blastomycosis: Avoid disturbing large areas of dirt and dust, especially in areas near water. If your job or hobbies expose you to soil that's likely to contain Blastomyces, wear an N95 (or KN95) respirator mask to help filter the air you breathe.
In episode 52 of Going anti-Viral, Dr Carlos del Rio joins host Dr Michael Saag to discuss the topic of providing care to foreign-born individuals. Dr del Rio is a Distinguished Professor of Medicine in the Division of Infectious Diseases at Emory University School of Medicine. He has held numerous positions at Emory University including as co-Director of the Emory Center for AIDS Research (CFAR) and co-PI of the Emory-CDC HIV Clinical Trials Unit and the Emory Vaccine and Treatment Evaluation Unit. He has worked more than a decade with hard-to-reach populations including people with substance use disorders to improve outcomes of those with HIV and to prevent infection with those at risk. Dr del Rio discusses steps his clinic has taken to provide care to hard-to-reach populations including understanding why patients miss appointments. Dr Saag and Dr del Rio also discuss the unique challenges that foreign-born individuals have in accessing care and the impact of current immigration enforcement on people in need of care and on the broader healthcare workforce. Dr del Rio shares his personal family history with immigration to illustrate the diverse nature of foreign-born people in the United States. Dr Saag and Dr del Rio close by emphasizing the need for clinicians to be passionate in providing care and compassion to their foreign-born patients at a time of immigration enforcement actions by federal authorities.0:00 – Introduction1:48 – Defining hard-to-reach populations 5:45 – How clinicians can provide access to care for hard-to-reach populations9:01 – Unique challenges that foreign-born individuals have in accessing care15:38 – Impact of current immigration enforcement on individuals in need of care and on the healthcare workforce19:08 – Diversity of foreign-born individuals in the US and Dr del Rio's personal family history with immigration25:57 – The importance of passion and compassion to ensure foreign-born individuals feel welcome in the clinic __________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...
In this episode, we review the high-yield topic Actinomycosis from the Infectious Diseases section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
The adaptability of fungi to warmer temperatures is an obvious consequence of climate change. Perhaps less obvious is the role climate change has played on fungal pathogens emerging as a global health concern. While humans are mostly protected from fungal infections by our immune system and body temperature, a warming global climate could subvert the status quo. Some fungi are already adapted to warmer temperatures and causing invasive acute infections in humans: Candidozyma auris, Cryptococcus neoformans, and Aspergillus fumigatus, to name a few. In this episode of Communicable, Angela Huttner and Josh Nosanchuk invite Arturo Casadevall, a Bloomberg Distinguished Professor at Johns Hopkins and this year's recipient of ESCMID's Excellence in Science Award, to discuss the world of fungi and their pathogenic potential in a warming world. Other topics include how to prepare for their emergence as a health threat, how fungi can be harnessed for applications that can benefit us, and ultimately answering the question Casadevall himself posed in the title of his recently published book, What if fungi win?This episode was edited by Kathryn Hostettler and peer reviewed by Robin Aerts of University Hospital Antwerp, Belgium. References1. Casadevall, A with Desmon S. What if fungi win? Johns Hopkins University Press, 2024.2. Smith DFG, et al. Environmental fungi from cool and warm neighborhoods in the urban heat island of Baltimore City show differences in thermal susceptibility and pigmentation. BioRxiv 2025. DOI: 10.1101/2023.11.10.566554 3. Casadevall A and Pirofski L. Benefits and Costs of Animal Virulence for Microbes. mBio 2019. DOI: 10.1128/mBio.00863-194. Cordero RJB et al. Radiation protection and structural stability of fungal melanin polylactic acid biocomposites in low Earth orbit. PNAS 2025. DOI: 10.1073/pnas.24271181225. Dadachova E, et al. The radioprotective properties of fungal melanin are a function of its chemical composition, stable radical presence and spatial arrangement. Pigment Cell Melanoma Res 2008. DOI: 10.1111/j.1755-148X.2007.00430.x6. Cordero RJB et al. The hypothermic nature of fungi. PNAS 2022. DOI: 10.1073/pnas.2221996120
Leonard is asking how one acquires Lyme disease, and how doctors diagnose it. James Tytko asked Jack Lambert, Professor and Consultant in Infectious Diseases at Mater Misericordiae University Hospital, for help to find an answer. Like this podcast? Please help us by supporting the Naked Scientists
This week, Luis is joined by Dr. Christopher Doern from VCU Health to explore the complex world of diabetic wound cultures. How does diabetes impair wound healing—and what makes these infections so difficult to diagnose and treat? Dr. Doern dives into the microbiology behind diabetic foot wounds, highlighting the impact of bacterial diversity, specimen quality, and the limitations of traditional culture methods. He also shares best practices for workup strategies and antibiotic selection in these often polymicrobial infections. Link to studies mentioned in the episode: https://pubmed.ncbi.nlm.nih.gov/28669650/ https://doi.org/10.1111/j.1742-481X.2011.00937.x https://academic.oup.com/ofid/article/10/10/ofad495/7292955 Want to be added to Dr. Doern's email list? Reach out to christopher.doern@vcuhealth.org Questions? Feedback? Send those to letstalkmicro@outlook.com Want to support the podcast? Here's how: Venmo: https://venmo.com/u/letstalkmicro Buy me a Ko-fi: https://ko-fi.com/letstalkmicro
On episode #84 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/17 – 7/2/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Clinical Outcomes and Perspectives of People With Human Immunodeficiency Virus Type 1 Twelve Months After Initiation of Long-acting Cabotegravir and Rilpivirine in an Observational Real-world US Study (BEYOND)(CID) Healthcare Provider Knowledge of West Nile Virus Diagnostic Testing—United States, 2022 (OFID) Bacterial Risk and Distribution of Metastatic Infections by Primary Infection Focus in Staphylococcus aureus Bacteremia (OFID) Clinical management of Clostridioides difficile infection with faecal microbiota transplantation (eClinicalMedicine) Clinical Practice Guidelines for the Management of Clostridioides difficile Infection in Adults (IDSA) Clinician Management Preferences for Clostridioides difficile Infection in Adults (OFID) Donor-Derived Tuberculosis In Three Solid Organ Transplant Recipients From The Same Donor (OFID) Septic Arthritis and Osteomyelitis in Finger Caused by Mycoplasma phocimorsus from Brown Bear, Alaska, USA (CDC: Emerging Infectious Diseases) Foodborne Botulism Outbreak After Consumption of Home-Canned Cactus (Nopales) (CDC: MMWR) One-Stage Revision Total Hip Arthroplasty for Polymicrobial Periprosthetic Joint Infection Leads to High Reinfection Rates (Journal of Arthroplasty) 4,000-year-old Mycobacterium lepromatosis genomes from Chile reveal long establishment of Hansen's disease in the Americas (Nature Ecology & Evolution) Fungal The Last of US Season 2 (YouTube) Outcome Predictors of Candida Prosthetic Joint Infection (OFID) Parasitic Miscellaneous Ten Practical Tips for a Successful Presentation at ID clinical case conference (OFID) Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030 (LANCET) Comparison of Periodic In-Person ID Care to Daily Tele-ID Care at a Community Hospital (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
Want to elevate your infection prevention career? Dive into this inspiring episode with Gail Fraine and Dr. Mayar Al Mohajer as they explore the value, purpose, and impact of the Advanced Leadership Certification in Infection Prevention (AL-CIP). Learn how this credential empowers professionals to lead change, drive outcomes, and shape healthcare policy. Get tips for submission success and hear firsthand experiences from these certified leaders! Hosted by: Kelly Holmes, MS, CIC, FAPIC and Lerenza L. Howard, MHA, CIC, LSSGB About our Guests: Gail Fraine, CIC, LTC-CIP, AL-CIP Gail Fraine is the System Director of Infection Prevention at Ascension Saint Thomas in Nashville, TN, with over 30 years of experience reducing healthcare-associated infections through evidence-based practices and high-reliability principles. A long-standing APIC member, she has held national leadership roles including Board Director and Annual Conference Chair. Gail currently serves as President-Elect of the Certification Board of Infection Control and Epidemiology (CBIC) and contributed to developing both the long-term care and Advanced Leadership certifications. She holds nursing degrees from Arkansas State, Belmont, and Vanderbilt, and is certified in CIC, LTC-CIP, and AL-CIP. Mayar Al Mohajer, FIDSA, FSHEA, FAPIC, FACHE, AL-CIP Dr. Al Mohajer serves as Professor of Medicine in the Section of Infectious Diseases at Baylor College of Medicine in Houston, Texas, where he also directs the Infection Prevention, Antimicrobial Stewardship, Quality Improvement, and Leadership Track. He is the Chief of the Infectious Disease Section at Baylor St. Luke's Medical Center and the Medical Director of Infection Prevention, Occupational Health, Diagnostic Stewardship, and Antibiotic Stewardship for CommonSpirit Health's South Region and Baylor St. Luke's Medical Center. In addition to his clinical and academic roles, Dr. Al Mohajer sits on the CBIC Board and co-chairs the National Infection Prevention Council for CommonSpirit Health. He holds multiple fellowships and certifications recognizing his expertise and leadership, including FIDSA, FSHEA, FAPIC, FACHE, and AL-CIP.
This guest episode is packed with profound insights from a highly accomplished female specialist physician who is now pivoting into leadership coaching. Dr Julie Trivedi, an Infectious Disease specialist based in Dallas Texas, shares her personal journey into medicine and the challenges she encountered along the way on the path to climbing the ladder of professional success. Most importantly, she is now using her own experience as a female leader within the medical community to coach other women leaders in healthcare who encounter similar challenges - teaching them to love themselves and advocate for their space as women leaders, without sacrificing their well-being. MORE WAYS TO CONNECT: Learn more about Dr Julie Trivedi at www.julietrivedimd.com or visit her substack https://julietrivedimd.substack.com/ Follow our LinkedIn page: https://www.linkedin.com/company/104404906/admin/dashboard/ Join the Movement on Instagram: @lifebeyondclinicalpractice Connect to our free Private Community: https://www.facebook.com/groups/897241125152990 Rate and Review the show on Apple Podcasts https://podcasts.apple.com/us/podcast/life-beyond-clinical-practice-healthcare-careers-professional/id1713086617 Book a free Complimentary Call with Dr Diane https://calendly.com/lbcp/complimentary-call Enjoyed this episode? We think you'll enjoy this one too https://podcasts.apple.com/ca/podcast/85-the-first-and-most-important-step-in-embarking/id1713086617?i=1000699463041
Whether you are human or computer, viruses can ruin your day, so taking steps to avoid them is important. This lecture will ask whether there are similarities between human immunity and computer immunity? Can we use discoveries in one system to help protect against infections in the other? Might we one day take our laptops for regular vaccinations, or run a ‘software update' on our own immune systems to avoid an emerging pathogen?This lecture was recorded by Robin May & Victoria Baines on 7th May 2025 at Barnard's Inn Hall, London.Robin is Gresham Professor of Physic.He is also Chief Scientific Adviser at the Food Standards Agency (FSA) and Professor of Infectious Disease at the University of Birmingham.Victoria is IT Livery Company Professor of Information Technology.Victoria is a Senior Research Associate of the Intellectual Forum at Jesus College, Cambridge, a Senior Research Fellow of the British Foreign Policy Group, and a Fellow of the British Computer Society. She is also Visiting Fellow at Bournemouth University's School of Computing, a former Visiting Research Fellow at Oxford University, and was a guest lecturer at Stanford University in 2019 and 2020. She is a graduate of Trinity College, Oxford and holds a doctorate from the University of Nottingham. She serves on the Safety Advisory Board of Snapchat, the Advisory Board of cybersecurity provider Reliance Cyber, and is a trustee of the Lucy Faithfull Foundation.The transcript of the lecture is available from the Gresham College website: https://www.gresham.ac.uk/watch-now/do-computers-get-sick-how-humans-and-computers-fight-virusesGresham College has offered free public lectures for over 400 years, thanks to the generosity of our supporters. There are currently over 2,500 lectures free to access. We believe that everyone should have the opportunity to learn from some of the greatest minds. To support Gresham's mission, please consider making a donation: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-todayWebsite: https://gresham.ac.ukTwitter: https://twitter.com/greshamcollegeFacebook: https://facebook.com/greshamcollegeInstagram: https://instagram.com/greshamcollegeSupport Us: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-todaySupport the show
Dr. Jay Butler is an infectious disease physician, epidemiologist, and former Deputy Director for Infectious Diseases at the CDC. We had the joy of hosting Dr Butler in the BioLogos offices recently where we shared his perspective on public health as a ministry, discussing his career journey from the CDC to working with Alaska Native communities. He also delves into the history of measles, its impact, and the groundbreaking development of the MMR vaccine, which has saved millions of lives globally. The conversation explores the challenges of public trust in medical research and institutions, especially concerning vaccines, and how science and faith can come together to pursue truth and improve public health outcomes. Theme song and credits music by Breakmaster Cylinder. Other music in this episode by Dark Blue Studio courtesy of Shutterstock, Inc. Additional Resources: BioLogos Open Letter to People of Faith about Science BioLogos Common Question - Should Christians Get Vaccinated?
Recorded live at ASM Microbe 2025, this episode captures the energy of the American Society for Microbiology's annual event. Luis shares his top takeaways from the conference floor—including standout poster presentations, emerging technologies, and trending topics in microbiology. One clear theme dominated this year: rapid diagnostics for identification and susceptibility testing. Tune in for a front-row seat to the latest in clinical microbiology innovation. Questions? Feedback? Send those to letstalkmicro@outlook.com Want to support the podcast? Here's how: Venmo: https://venmo.com/u/letstalkmicro Buy me a Ko-fi: https://ko-fi.com/letstalkmicro
Professor Adam Kucharski joins Gavin & Jessamy to discuss the intersection of mathematics, epidemiology, and truth, off the back of his new book, Proof. How do we generate scientific knowledge? How can we communicate uncertainty? What is the impact of social media and artificial intelligence on public trust in science?Adam also tells us about the importance of public engagement, the nuances of misinformation, the importance of transparency in policy, the future of scientific communications, the need for adaptable definitions of proof, and the value of pragmatic, transparent approaches to decision-making in health and science.Send us your feedback!Read all of our content at https://www.thelancet.com/?dgcid=buzzsprout_tlv_podcast_generic_lancetCheck out all the podcasts from The Lancet Group:https://www.thelancet.com/multimedia/podcasts?dgcid=buzzsprout_tlv_podcast_generic_lancetContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
Listen as expert faculty answer your most pressing questions on optimizing immunization in clinical practice.Topics covered include:Practical methods for improving confidence in vaccinesHow to educate patients on vaccine development and safety monitoring Effective strategies to tailor recommendations, such as motivational interviewingWays to navigate clinical encounters and address vaccine hesitancyPresenters:Robert H. Hopkins, Jr., MD, MACPProfessor of Internal Medicine and PediatricsUniversity of Arkansas for Medical SciencesCollege of MedicineLittle Rock, ArkansasLitjen (L.J.) Tan, MS, PhDChief Policy and Partnership Office, Immunize.orgChair, National Adult Influenza Immunization SummitCo-Chair, Global Influenza InitiativeSt Paul, MinnesotaLink to full program: https://bit.ly/3I5jBh0Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
Rat lungworm disease is on the rise in eastern Australia in dogs – and there have even been recorded cases in humans, including two known lethal incidents. Research by veterinary scientists at the University of Sydney has unveiled insights into what is behind the growth in the disease, also known as neural angiostrongyliasis. Their study, published in The Journal of Infectious Diseases, highlights how climatic factors act as drivers for this potential public health issue. Joining me to discuss this is Professor Jan Slapeta, Dr Slapeta is a Professor of Veterinary and Molecular Parasitology at the University of Sydney and senior author of the paper. Rainfall- and Temperature-Driven Emergence of Neural Angiostrongyliasis in Eastern Australia, 2020–2024
Meningitis remains a major global health threat, with an estimated 2.5 million cases each year; of these, one in six results in death and one in five in long-term disabilities. Although meningitis “can strike anyone, anywhere in the world,” outbreaks disproportionately impact low- and middle-income countries, where diagnostic and treatment resources are limited. In efforts to address this, WHO launched its first-ever guideline on meningitis diagnosis and management in April this year. In this episode of Communicable, hosts Emily McDonald and Marc Bonten are joined by two experts directly involved in creating the guideline, Lorenzo Pezzoli and Nicolò Binello (WHO), as well as Jacob Bodilsen (Aalborg University), clinician-researcher and Chair of ESCMID's Study Group for Infectious Diseases of the Brain (ESGIB). The guests offer a firsthand look behind the guideline's development, review key recommendations for diagnosis and treatment - including the use of lumbar puncture, antibiotics, and chemoprophylaxis – and discuss how these fit into various clinical settings. This episode was edited by Kathryn Hostettler and peer reviewed by Ljiljana Lukić of University Hospital for Infectious Diseases in Zagreb, Croatia. The executive producer of Communicable is Angela Huttner. TermsCRP, C-reactive proteinGDG, Guideline Development GroupLiterature WHO guidelines on meningitis diagnosis, treatment and care. April 2025. https://www.who.int/publications/i/item/9789240108042Defeating meningitis by 2030: a global road map. June 2021. https://www.who.int/publications/i/item/9789240026407Olie SE, et al. Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningitis: a prospective diagnostic accuracy study. Lancet Reg June 2025. DOI: 10.1016/j.lanepe.2025.101309Coldiron ME, et al. Single-dose oral ciprofloxacin prophylaxis as a response to a meningococcal meningitis epidemic in the African meningitis belt: A 3-arm, open-label, cluster-randomized trial. PloS Med 2018. DOI: 10.1371/journal.pmed.1002593Hasbun R, et al. Computed tomography of the head before lumbar puncture in adults with suspected meningitis. N Engl J Med 2001. DOI: 10.1056/NEJMoa010399Glimåker M. Lumbar puncture in adult bacterial meningitis: time to reconsider guidelines? BMJ 2013, DOI: 10.1136/bmj.f361
Health Secretary Robert F. Kennedy's revamped CDC vaccine advisory board stopped recommending certain flu vaccines this week. On this week's On the Media, a scientist debunks the claims that RFK, Jr.'s appointees are making. Plus, how the media covered the U.S. bombing of Iran.[00:00] Host Micah Loewinger unspools the Trump administration's attempts to control the narrative around the war in Iran, including the president's insistence on the “total obliteration” of Iran's nuclear sites, conflicting reports over whether or not Iran had a nuclear weapons program in the works, and how the media is missing the mark.[00:00] Host Brooke Gladstone speaks with Paul Offit, the director of the Vaccine Education Center and a physician in the Division of Infectious Diseases at Children's Hospital of Philadelphia, about how the Secretary of Health and Human Services, Robert F. Kennedy Jr., purged the CDC's vaccine advisory committee members, the controversial figures Kennedy replaced them with, and what impact this will have on the future of vaccines and immunology in the US. [00:00] Brooke continues her conversation with Paul Offit about the new controversial figures appointed to the CDC's vaccine advisory committee, and how science communication could improve in the next public health crisis. Further reading:“Lawmakers and Pundits Speed Run Iraq WMDs-Level Lies About Iran,” by Sarah Lazare and Adam Johnson“Donald Trump and Sean Hannity Set Off a Wave of Disinformation After Iran Bombing,” by David Gilbert On the Media is supported by listeners like you. Support OTM by donating today (https://pledge.wnyc.org/support/otm). Follow our show on Instagram, Twitter and Facebook @onthemedia, and share your thoughts with us by emailing onthemedia@wnyc.org.
In this special LIVE podcast episode, Drs. Zahra Kassamali Escobar (@zkepharmD) and Jamie Wagner (@jamiewagner) present the latest and greatest in ID literature from MAD-ID 2025 (@MAD_ID_ASP) in Orlando, FL. They cover everything from ground-breaking randomized controlled trials and updates to the treatment of resistant gram-negatives to exciting pipeline agents. If you're behind on what has been published recently in ID, this episode is for you! Google Drive to Slides from Live Session: https://drive.google.com/file/d/1HdPEJUA2EXk0xL3JKJfuV9-HdGjgRnSD/view?usp=drivesdk How to Obtain BCIDP Recertification Credit for this Episode: Visit sidp.org/BCIDP for more information Breakpoints merchandise is available at https://sidp.toptierstores.com/ Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/. Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.
In this episode, Dr. Sergio Zanotti discusses the different aspects of managing pneumonia in critically ill patients. He covers the initial management of severe pneumonia, management of ventilator-associated pneumonia, and highlights the clinical approach to non-resolving pneumonia in the intensive care unit (ICU). He is joined by Dr. Andre Kalil, a physician specializing in critical care and infectious diseases. Dr. Kalil is a Professor in the Division of Infectious Diseases and Director of Transplant Infectious Diseases at the University of Nebraska Medical Center (UNMC). Additional resources: How to approach a patient hospitalized for pneumonia who is not responding to treatment? Pedro Povoa, et al. Intensive Care Med 2025: https://link.springer.com/article/10.1007/s00134-025-07903-3 Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Andre Kalil, et al. Clin Infect Dis. 2016: https://pmc.ncbi.nlm.nih.gov/articles/PMC4981759/ Management of Ventilator-Associated Pneumonia: Guidelines. M Metersky and Andre c. Kalil. Infect Dis Clin North Am. 202: https://pubmed.ncbi.nlm.nih.gov/38280768/ Hydrocortisone in Severe Community-Acquired Pneumonia. CAPE-COD Clinical Trial. N Eng J of Med 202: https://www.nejm.org/doi/full/10.1056/NEJMoa2215145 Continuous vs. Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients with Sepsis. BLING III Clinical Trial. JAMA 2024: https://jamanetwork.com/journals/jama/fullarticle/2819971 Music mentioned in this episode: Pat Metheny Group – We Live Here: https://bit.ly/44gt8Jl Antonio Carlos Jobin – Terra Basilis: http://bit.ly/4k4Amq1 Mahler: Symphony No.9 – Chicago Symphony Orchestra: http://bit.ly/4k9sXWn
In this episode of Let's Talk Micro, we dive into the fast-paced world of rapid antimicrobial susceptibility testing (AST). Recorded live from ASM Microbe 2025, Luis is joined by Dr. Carey-Ann Burnham, CEO of Pattern Bioscience and Editor-in-Chief of the ASM Case Reports journal. Together, they explore how innovative technologies—like single-cell microbiology—are transforming clinical microbiology and accelerating diagnostic results. What is single-cell microbiology, and how does it improve rapid diagnostics? They also discuss case reports from ASM that highlight the real-world impact of timely diagnostic tools on patient care. It's where speed meets science—and the stories behind the data truly matter. Questions? Feedback? Send those to letstalkmicro@outlook.com Want to support the podcast? Here's how: Venmo: https://venmo.com/u/letstalkmicro Buy me a Ko-fi: https://ko-fi.com/letstalkmicro
On episode #83 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/5 – 6/18/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Premature Demise of the Milwaukee Protocol (CID) West Nile Virus and Other Nationally Notifiable Arboviral Diseases — United States, 2023 (CDC: MMWR) Investigation of associations between the neonatal gut microbiota and severe viral lower respiratory tract infections in the first 2 years of life (LANCET: Microbe) Right blend of gut microbiota could avert hospitalization forviral respiratory infection in babies (CIDRAP) Clinical management and infection prevention and control for mpox: living guideline, May 2025 (World Health Organization) Bacterial Corynebacterium diphtheriaeOutbreak in Migrant Populations in Europe (NEJM) Weekly Oral Cycling Antibiotic Treatment: A New Antibioprophylaxis Regimen for Recurrent UTIs (CID) Fungal The Last of US Season 2 (YouTube) Estimated Burden of Coccidioidomycosis (JAMA) Antifungal therapy in Candida infective endocarditis: a comparison of echinocandins and other treatment regimens in a nation-wide cohort study (CID) Parasitic Does schistosome infection affect behavior through the gut-brain axis? (PLoS Neglected Tropical Diseases) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
Dr. Anthony Fauci, the physician-scientist who helped steer America through its greatest public health challenges, joins Guy Kawasaki for an illuminating conversation on Remarkable People. From his early days combating the AIDS epidemic to leading the nation's COVID-19 response across seven presidential administrations, Dr. Fauci takes us behind the scenes of the most pivotal moments in modern public health. He shares untold stories about developing breakthrough vaccines, standing firm in the face of political pressure, and maintaining scientific integrity during times of crisis. With characteristic candor, Dr. Fauci reflects on his legacy as the former director of the National Institute of Allergy and Infectious Diseases and offers vital insights about preparing for future global health challenges.Listen to Remarkable People here: **https://podcasts.apple.com/us/podcast/guy-kawasakis-remarkable-people/id1483081827**See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Join us on WarDocs as we explore the fascinating journey of Army Colonel Aaron C. Pitney, MD, into the world of military medicine. Inspired by his family's legacy in the medical field, Dr. Pitney shares how his sister and brother-in-law's careers in pediatrics and cardiology motivated him to pursue his own path in medicine. Discover how his training at Tripler and mentorship in pediatric hematology and oncology played a pivotal role in shaping his career. Dr. Pitney recounts a poignant case of a young leukemia patient, which mirrored his own family, highlighting the profound personal impact of his work. Listen in as we uncover the critical work at the US Army Medical Research Institute of Infectious Diseases (USAMRIID) in biodefense research. We highlight their mission to protect military and public health from biological threats, showcasing their efforts in developing vaccines and diagnostic tools. Dr. Pitney discusses the importance of collaboration between military and civilian sectors during public health emergencies, such as COVID-19, and emphasizes the vital role of prevention, detection, and rapid response in ensuring safety against emerging diseases. Gain insight into the rigorous safety protocols and operations at USAMRIID's high-stakes biocontainment facilities. Learn about the meticulous procedures in place to protect personnel and the community, from donning protective suits to maintaining negative pressure environments. We also explore recent advancements in military medicine technology, such as the Dragon Medic diagnostic tool, and reflect on the leadership journey of a seasoned military medical commander. Throughout this engaging episode, Dr. Pitney's dedication to patient care and the significant contributions of military medical professionals in diverse and demanding environments are vividly illustrated. Chapters: (00:04) Military Medicine Journey and Impact (14:33) Biodefense Research and Safety Measures (25:26) Biosafety Protocols and Personnel Composition (40:22) Advances in Military Medicine Technology Chapter Summaries: (00:04) Military Medicine Journey and Impact Army Colonel Aaron C. Pitney, MD's journey into military medicine was inspired by his family and mentors, his experiences in pediatric oncology, and his deployment in Iraq. (14:33) Biodefense Research and Safety Measures USAMRID's biodefense work includes rapid pathogen testing, countermeasures development, and integration with medical care. (25:26) Biosafety Protocols and Personnel Composition USAMRIID's safety protocols include protective suits, secure packaging, and alignment with funding and objectives. (40:22) Advances in Military Medicine Technology Dragon Medic, a cutting-edge diagnostic tool, and the evolving "why" of a military medical leader with 30+ years of experience. Take Home Messages: The Intersection of Military Medicine and Personal Inspiration: The episode explores the powerful impact of personal and family influences on career choices within military medicine, highlighting the significant role that mentors and family members play in shaping one's path and dedication to patient care. Challenges and Resilience in Biodefense: The episode delves into the critical work at the US Army Medical Research Institute of Infectious Diseases, emphasizing the importance of safety protocols, rapid pathogen testing, and vaccine development in protecting against biological threats. It underscores the resilience required to operate in high-stakes environments. Leadership in Evolving Medical Landscapes: Through the narrative of transitioning from clinical roles to leadership positions, the episode underscores the importance of adaptability, the management of diverse teams, and the strategic collaboration between military and civilian sectors, especially during public health emergencies like COVID-19. Technological Innovations in Military Healthcare: The discussion highlights advancements in military medicine technology, such as the development of cutting-edge diagnostic tools. It reflects on the necessity of leadership in setting conditions for clinical success and ensuring the robustness and resilience of the military health system. Commitment to Safety and Community: The episode provides an in-depth look at the meticulous safety measures and community responsibilities associated with biocontainment work at Fort Detrick. It highlights the collaborative effort required to maintain high safety standards and the dedication of personnel to ensuring the well-being of both military and public health. Episode Keywords: Military medicine, USAMRIID, Colonel Dr. Aaron C. Pitney, biodefense, pediatric oncology, Army healthcare, medical innovation, biological threats, military leadership, Dragon Medic diagnostic tool, Fort Detrick, US Army Medical Research Institute of Infectious Diseases, pathogen testing, vaccine development, safety protocols, biodefense research, military and civilian collaboration, public health emergencies Hashtags: #MilitaryMedicine #LeadershipInMedicine #InnovationInHealthcare #ColonelPitney #USAMRIID #Biodefense #PediatricOncology #MilitaryLeadership #HealthcareInnovation #BiologicalThreats Honoring the Legacy and Preserving the History of Military Medicine The WarDocs Mission is to honor the legacy, preserve the oral history, and showcase career opportunities, unique expeditionary experiences, and achievements of Military Medicine. We foster patriotism and pride in Who we are, What we do, and, most importantly, How we serve Our Patients, the DoD, and Our Nation. Find out more and join Team WarDocs at https://www.wardocspodcast.com/ Check our list of previous guest episodes at https://www.wardocspodcast.com/our-guests Subscribe and Like our Videos on our YouTube Channel: https://www.youtube.com/@wardocspodcast Listen to the “What We Are For” Episode 47. https://bit.ly/3r87Afm WarDocs- The Military Medicine Podcast is a Non-Profit, Tax-exempt-501(c)(3) Veteran Run Organization run by volunteers. All donations are tax-deductible and go to honoring and preserving the history, experiences, successes, and lessons learned in Military Medicine. A tax receipt will be sent to you. WARDOCS documents the experiences, contributions, and innovations of all military medicine Services, ranks, and Corps who are affectionately called "Docs" as a sign of respect, trust, and confidence on and off the battlefield,demonstrating dedication to the medical care of fellow comrades in arms. 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Jessica Malaty Rivera is an infectious disease epidemiologist and science communicator renowned for making complex public health information accessible, particularly during the COVID-19 pandemic. While initially premed at USC, she pivoted to studying health promotion and disease prevention, and worked in the nonprofit sector after college. She was later recruited to research emerging biological threats at Georgetown University and simultaneously decided to pursue a master's degree there in biohazardous threat agents and emerging infectious diseases. While she's always loved science, she began to realize that where she truly excelled was in “speaking science.” And the deeper Rivera got into infectious disease epidemiology—whether through work or academia—the more she realized how critical the communications aspect of science was to public health. When the COVID-19 pandemic hit, she joined The Atlantic to lend her expertise to the COVID Tracking Project to provide publicly available, comprehensive data on COVID-19 cases in real time. She then began using Instagram to explain and interpret global health news, unexpectedly gaining a large following for her easy-to-understand information. Over the past five years, she has grown her platform, launched a Substack, and is currently completing a Doctorate in Public Health from Johns Hopkins University, all while remaining dedicated to science facts and public health literacy.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Whether you realize it or not, our lives depend on the native plant communities that comprise and support regional biodiversity. As we lose habitat, we lose species, and we lose the checks and balances that keep the living world functional. Scientists are increasingly uncovering the links between human health issues like infectious diseases and biodiversity loss and that is exactly what Dr. James Shepherd and I discuss in this episode. Join us as we explore the links between habitat loss, native plant communities, and infectious diseases like Lyme disease. This episode was produced in part by Linda, Sylvan, Austin, Sarah, Ethan, Elle, Steve, Cassie, Chuck, Aaron, Gillian, Abi, Rich, Shad, Maddie, Owen, Linda, Alana, Sigma, Max, Richard, Maia, Rens, David, Robert, Thomas, Valerie, Joan, Mohsin Kazmi Photography, Cathy, Simon, Nick, Paul, Charis, EJ, Laura, Sung, NOK, Stephen, Heidi, Kristin, Luke, Sea, Shannon, Thomas, Will, Jamie, Waverly, Brent, Tanner, Rick, Kazys, Dorothy, Katherine, Emily, Theo, Nichole, Paul, Karen, Randi, Caelan, Tom, Don, Susan, Corbin, Keena, Robin, Peter, Whitney, Kenned, Margaret, Daniel, Karen, David, Earl, Jocelyn, Gary, Krysta, Elizabeth, Southern California Carnivorous Plant Enthusiasts, Pattypollinators, Peter, Judson, Ella, Alex, Dan, Pamela, Peter, Andrea, Nathan, Karyn, Michelle, Jillian, Chellie, Linda, Laura, Miz Holly, Christie, Carlos, Paleo Fern, Levi, Sylvia, Lanny, Ben, Lily, Craig, Sarah, Lor, Monika, Brandon, Jeremy, Suzanne, Kristina, Christine, Silas, Michael, Aristia, Felicidad, Lauren, Danielle, Allie, Jeffrey, Amanda, Tommy, Marcel, C Leigh, Karma, Shelby, Christopher, Alvin, Arek, Chellie, Dani, Paul, Dani, Tara, Elly, Colleen, Natalie, Nathan, Ario, Laura, Cari, Margaret, Mary, Connor, Nathan, Jan, Jerome, Brian, Azomonas, Ellie, University Greens, Joseph, Melody, Patricia, Matthew, Garrett, John, Ashley, Cathrine, Melvin, OrangeJulian, Porter, Jules, Griff, Joan, Megan, Marabeth, Les, Ali, Southside Plants, Keiko, Robert, Bryce, Wilma, Amanda, Helen, Mikey, Michelle, German, Joerg, Cathy, Tate, Steve, Kae, Carole, Mr. Keith Santner, Lynn, Aaron, Sara, Kenned, Brett, Jocelyn, Ethan, Sheryl, Runaway Goldfish, Ryan, Chris, Alana, Rachel, Joanna, Lori, Paul, Griff, Matthew, Bobby, Vaibhav, Steven, Joseph, Brandon, Liam, Hall, Jared, Brandon, Christina, Carly, Kazys, Stephen, Katherine, Manny, doeg, Daniel, Tim, Philip, Tim, Lisa, Brodie, Bendix, Irene, holly, Sara, and Margie.
This episode packs an impactful punch and is a can't-miss! Host Dr. Vin Gupta is joined by recently declared U.S. Senate candidate Dr. Annie Andrews, who is looking to unseat Lindsey Graham in 2026, for an expansive discussion on her candidacy, policy priorities, and broader calls to action. Afterwards, Dr. Sean O'Leary, Professor of Pediatrics and Chair of the Committee on Infectious Diseases at the American Academy of Pediatrics, provides much-needed clarity on the chaotic messaging about childhood vaccines that came out of HHS last week. Learn more about your ad choices. Visit megaphone.fm/adchoices
Joe Alton, MD is an actively-licensed physician, medical preparedness advocate, and retired Fellow of the American College of Surgeons and Life fellow of the American College of OB/GYN. Amy Alton, ARNP, CNM is an actively-licensed advanced practice nurse practitioner and certified nurse midwife. Together, they are the NY Times/Amazon bestselling authors of various books, including the Book Excellence Award winners: The Survival Medicine Handbook: The Essential Guide For When Help Is NOT On The Way, Alton's Antibiotics and Infectious Disease, and other books. They have also been contributors to magazines in the survival, homesteading, and preparedness genre. Their website at … Continue reading →