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Our remarkable guest is Katie Romanczuk from Chicago. Katie's journey is one of incredible resilience and strength, having faced a challenging medical history including a brain tumor diagnosis and multiple preventive surgeries for genetic cancer. She has battled through paralysis, relearned to walk and talk, and found innovative ways to manage her seizures. Join us as we dive into her inspiring story of determination and hope. Visit our website: CannabisHealthRadio.comFollow us on Facebook.Find us on Rumble.Buy NixT420 Odor Remover with this exclusive discount link for Cannabis Health Radio listeners.
Timestamps: 5:15 - Having a co-founder pass away 10:33 - Drug resistance and cancer patients 18:24 - Clinical development 23:17 - Raising a series A as a biotech 26:43 - Striking partnerships Check out the LinkedIn event for our livestream with Aurelio Perucca on May 22nd. About Stefanie Flückiger-Mangual: Stefanie Flückiger-Mangual is the co-founder and CEO at TOLREMO Therapeutics, a biotech startup on a mission to prevent non-genetic cancer drug resistance. She holds a PhD in Molecular and Translational Biomedicine from ETH and worked there as a Postdoctoral Researcher before starting TOLREMO in 2017 together with Wilhelm Krek, who has since tragically passed away. There is no shortage of cancer therapies in biotech and medtech, and one common problem that they face is drug resistance: even if a certain therapy is at first successful in reducing the tumor's size, patients sometimes develop a resistance to it, whether it be genetic or non-genetic, and the therapy stops working. To use a tech metaphor, genetic drug resistance is akin to a hardware problem, whereas non-genetic drug resistance is more similar to a software malfunction. Since non-genetic resistance is much more dynamic, it's harder to measure and combat — this is what Stefanie and her fellow researchers have been studying for the past few years. They discovered a pivotal mechanism that governs critical transcriptional resistance pathways, i.e., that stops cancer drug resistance as it emerges without interfering with cancer-unrelated pathways. TOLREMO recently completed its Series A financing, bringing their total amount raised to USD 39M. Their ultimate goal is to prove the efficacy of their treatment and join forces with a larger pharma company. Don't forget to give us a follow on Twitter, Instagram, Facebook and Linkedin, so you can always stay up to date with our latest initiatives. That way, there's no excuse for missing out on live shows, weekly giveaways or founders' dinners.
This playlist features live interviews recorded by Oncology Data Advisor at the 49th Annual Oncology Nursing Society (ONS) Congress in Washington, DC. For more information, visit OncData.com.
Rabbi Peter Kasdan and Dr. Liz Etkin-Kramer discuss Yodeah.org, their online portal for genetic screening and counseling of Jewish families for the BRCA gene and other genetic markers for cancer risk. [Read more...] The post Seekers of Meaning 4/12/2024: Rabbi Peter Kasdan and Dr. Liz Etkin-Kramer from Yodeah.org, providing genetic cancer counseling for Jewish families appeared first on Jewish Sacred Aging.
Join us in this enlightening episode as we dive deep into the world of hereditary cancer testing and its profound impact on patient management and risk reduction. Our expert guest, … Continued
50: If Your Mom Had Breast Cancer, Does that Mean You Will Too? A Candid Conversation with a Genetic Cancer Prevention Coach. This is a topic I don't know much about, so I was looking forward to interviewing Cancer Prevention Coach and nurse, Krista. Krista's focus is on genetic testing because she's tested positive for a strong breast cancer gene, and she believes it's the same gene that caused her mother's breast cancer. I've always wondered: if a close relative had cancer does that mean I will get it too? What can you do to prevent cancer if it's a big part of your family history? How “close” does the relative with cancer have to be to increase your own risk? Are there tests that you can take to see if you have strong cancer genes? Krista answered all these questions and so many more. This is a tough topic, and I'll be honest a little scary when you think about getting tested to see if you have a higher likelihood of cancer. But Krista is very clear that knowledge is power, and it's better to understand the risks in your genetics so you can take action to lower your risk. We had an enlightening conversation about stress and its link to cancer. We are both in agreement that organic is best when it comes to produce, but we also understand that it can also be very expensive. We discussed some unique ways to eat organic produce (she suggests eating 8-10 servings per day) without blowing your food budget. Krista, BSN, RN, combines her diverse training in traditional medicine, integrative oncology, and functional nutrition to her work with patients at high risk of cancer due to inherited genetic mutations and/or family history. She is currently finishing her Master's degree at Arizona state University as part of the first Medical Nutrition program in the country. Her focus is nutrigenomics and personalized cancer prevention. She has training through Harvard Medical School in cancer genomics, precision oncology, and immuno-oncology. Krista truly believes knowledge is power, and considers herself a life-long learner. Her passion for prevention began amidst her mother's 12+ year battle with breast cancer which was caused by a genetic mutation. Krista, who is also a carrier of this mutation, has since dedicated her career to educating herself about cancer and showing others how to decrease risk as much as possible. She wants others to understand that genetics is just a small piece of the puzzle, and that their DNA is not their destiny. She owns a private nutrition practice in which she works closely with patients to create individualized prevention plans, and offers various courses throughout the year. Her goal is to empower patients with integrative nutrition and lifestyle modifications and teach them how to “fill their plates, and their lives, with purpose.” To learn more about upcoming classes Krista will be offering, you can follow her on Instagram (@cancer.prevention.coach) This episode is sponsored in part by ButcherBox. I love using Bison! It's very nutrient dense and contains conjugated linoleic acid (I know, what the heck does that mean?), which means Bison has anti-inflammatory properties. Here are the other reasons why I love using Bison in place of ground beef: Higher amounts of omega three fatty acids. More b12, zinc, iron, and selenium than beef. Some studies show it's got four times the vitamin E compared to beef. Lower in calories and cholesterol. It is lower fat, so it will cook faster than ground beef. My friends at BB are offering a deal that they've never offered to anyone! I had to say "pretty please" a couple of times, and guess what? It worked! I can't tell you how long they will offer this deal to me, but here it is:
The St. John's Morning Show from CBC Radio Nfld. and Labrador (Highlights)
If you know you have an increased genetic risk of developing cancer, what kind of care would you like to receive? We hear from registered nurse Rebecca Puddester, and professor in the Faculty of Medicine, Holly Etchegary.
Lynch syndrome is a common and often under-diagnosed inherited condition that increases one's risk for a variety of cancers, including colon, rectal, uterine, ovarian, urinary tract, and others. Many individuals with a Lynch mutation develop related cancers at a much younger age than the general population. According to the National Cancer Institute, “It is estimated that 1 in every 280 Americans are living with Lynch Syndrome." Most people living. with this inherited condition are unaware of it, or are diagnosed only after they have developed cancer.Dave Dubin, Founder of “Alive and Kickn”and three-time Lynch Syndrome cancer survivor shares his personal story and talks about the inspiring work his organization is doing through research, advocacy, education and screening.
Dr. Eric Shah welcomes Genetic Counselor Heather Hampel from The Ohio State University College of Medicine, as well as Director of Clinical Services at Ambry Genetics, Kory Jasperson, to discuss the role virtual care has played in genetic cancer screening. Hear how Ambry's CARE genetic program can help practitioners identify patients at increased risk for hereditary diseases and why this system is so beneficial to patients.
"A tumor is certainly smarter than humans," says researcher Jyotsna Batra, discussing the ability of some tumors to change behaviors and progress through mutations. But she and other researchers are doing their best to utilize genome-wide associated studies to understand the genetic basis of stages of carcinogenesis. Listen and learn How her lab has identified 150 risk variants associated with prostate cancer, Why matching these variants with the aggressiveness and metastases of disease is an important step, How they must take into account the role of heterogeneity in these stages of research, and Why it's vital when assessing carcinogenesis and oncogenesis to combine multiple diagnostic methods, like PSA tests alongside genetic tests, to better understand potential for disease progression. Jyotsna Batra is an associate professor with the Faculty of Health and School of Biomedical Sciences at Queensland University of Technology (QUT). She works in genetics, biochemistry, and cell biology and is currently focusing on prostate cancer research. Her lab has recently joined a large prostate cancer consortium known as the Practical Consortium led by the Institute of Cancer Research in London. This teaming up offers the world a major cooperative workforce undertaking genome-wide association studies to understand the genetic basis of cancer. She describes one of her major projects: a germ-line study involving chip technology that has allowed her to identify 150 risk variants associated with prostate cancer risk. As Richard asks about possible directions prostate cancer research could take, she illustrates the challenges and breakthroughs, from the role of heterogeneity as research progresses to what liquid biopsies can offer.Her work with biomarkers is directed at identifying aggressiveness as she looks at plasma and blood for secretory tumor cells and microRNAs. She is able to give a succinct reason for why prostate cancer might evade treatment, namely the possibilities of multiple origins for a tumor as well as developed resistance to drugs. Finally she shares an important finding from her lab involving what diagnostic tests should be combined. Listen in for more about this exciting and life-saving work. Available on Apple Podcasts: apple.co/2Os0myK
This year, nearly 1.7 million Americans will be diagnosed with cancer. Most will find out in the usual way; after having tiny blobs of tissue slurped up through a needle, smeared and stained on a slide, and put under the discerning eye of a pathologist. But starting this week, Medicare patients with advanced cancers will have access to a more 21st century diagnostic: Their cells can now be sequenced, matching patients with the drugs most likely to make a difference.
How well do you know your family history? It can help your healthcare provider assess your genetic cancer risk and determine whether or not you are a candidate for genetic testing. Yvonne Ruddy-Stein, APRN, Polokoff Breast Care in Southbury, joins Robin Sills, RN, host of "Medically Speaking," for a discussion about genetic testing and counseling, Lynch Syndrome, and how genetic mutations can increase your risk of breast, ovarian, colorectal and other cancers.
Frankly Speaking About Cancer with the Cancer Support Community
How do you know if you're genetically predisposed to developing cancer? Oftentimes, cancer occurs sporadically—from gene mutations occurring over the course of a lifetime. However, about 10 percent of all incidences of cancer are caused by inherited gene mutations which increase the risk for developing certain types of cancer. When several people in your family have been diagnosed with cancer, many physicians may refer you to genetic testing. On this episode of Frankly Speaking About Cancer, we're exploring one particular type of test, multi-gene panel testing.
Frankly Speaking About Cancer with the Cancer Support Community
Listen in as Dr. Mike provides the answers to a wealth of health and wellness questions.Here you'll find the answers to a wealth of health and wellness questions posed by Healthy Talk fans.Listen in because what you know helps ensure healthy choices you can live with. Today on Healthy Talk, you wanted to know:I don’t want to get cancer, but I have a family history of cancer. What can I do to decrease my odds?The key to cancer prevention is keeping your cells healthy. Cancer is a cell gone bad. The basic blueprint that drives the engine of a cell turns bad when you have cancer. The genetic makeup gets mutated.Do things to promote DNA health. Broccoli is a cruciferous vegetable. Cruciferous vegetables preserve the integrity of DNA. Watercress, kale, cauliflower are also cruciferous. Eat at least a serving or two of cruciferous vegetables every day. The isothiocyanate inside is what protects your DNA. Diet is first, but it would be difficult to get enough isothiocyanate from just vegetables. Supplementation will help. Look for a product that lists the amount of isothiocyanate on the label.Curcumin is the workhorse of cell health. It seems to benefit every organ system in the body. Try 400 mg a day.If you have a health question or concern, Dr. Mike encourages you to write him at askdrmikesmith@radiomd.com or call in, toll-free, to the LIVE radio show (1.844.305.7800) so he can provide you with support and helpful advice.
Bill Henderson interviews Dr. John Hall, the Director of Research for Natural Source International in New York City. Dr. Hall explains the action of several of Natural Source’s products; in particular, one which Bill has found improved his prostate problems dramatically: Prostabel. Dr. Hall also describes Ladybel (for women) and Real Build. Stay tuned ’til the end to hear … Read more about this episode...
Bill Henderson interviews Dr. John Hall, the Director of Research for Natural Source Int’l. in New York City. Dr. Hall explains the action of several of their products. One in particular which Bill has found improved his prostate problems dramatically is called Prostabel. Dr. Hall also describes Ladybel and Real Build. A special discount of 20% on the first order … Read more about this episode...
Bill Henderson interviews Dr. John Hall, the Director of Research for Natural Source Int’l. in New York City. Dr. Hall explains the action of several of their products. One in particular which Bill has found improved his prostate problems dramatically is called Prostabel. Dr. Hall also describes Ladybel and Real Build. A special discount of 20% on the first order … Read more about this episode...