Podcasts about Predisposition

LIFE’S BOOMING SERIES 6: Dying to Know Episode 6: Finding the funny side Many of us are embracing more humour following the death of a loved one. But how do we make space for laughter without feeling like we’re getting it wrong? Comedian Michelle Brasier and grief counsellor Marianne Bowdler share their experiences. About the episode – brought to you by Australian Seniors. Join James Valentine for the sixth season of Life’s Booming: Dying to Know, our most unflinching yet. We’ll have the conversations that are hardest to have, ask the questions that are easy to ignore, and hear stories that will make you think differently about the one thing we’re all guaranteed to experience: Death. In this episode, we explore the psychology behind our fear of death and how humour can help us face it. From heartfelt eulogies that land a laugh to finding the line between lightness and respect, we look at how Australians are using comedy to cope, connect and heal. Michelle Brasier is an award-winning comedian, writer and performer known for her sharp wit, musical talent and deeply personal storytelling. After losing both her father and brother to cancer, Michelle channelled her grief into her stage show Average Bear (on ABC iview), and book My Brother's Ashes are in a Sandwich Bag, which blend humour, vulnerability and hope. Marianne Bowdler is the clinical services manager at Griefline, where she supports Australians experiencing grief, loss and trauma. She draws on years of experience to explain how laughter, when used thoughtfully, can offer relief, connection and healing. If you have any thoughts or questions and want to share your story to Life’s Booming, send us a voice note – lifesbooming@seniors.com.au Watch Life’s Booming on YouTube Listen to Life's Booming on Apple Podcasts Listen to Life's Booming on Spotify For more information visit seniors.com.au/podcast Produced by Medium Rare Content Agency, in conjunction with Ampel Sonic Experience Agency -- Disclaimer: Please be advised that this episode contains discussions about death, which may be triggering or upsetting for some listeners. Listener discretion is advised. If you are struggling with the loss of a loved one, please know that you are not alone and there are resources available. For additional support please contact Lifeline on 131 114 or Beyond Blue on 1300 224 636. TRANSCRIPT: S06EP06 Finding the funny side James: Hello and welcome to Life's Booming. I'm James Valentine and this season we're talking about death, but it's not all doom and gloom. On this episode we're going to embrace the funny side of grief. Forty-seven percent of the over 50s want to embrace more humor following the death of a loved one, according to an Australian senior's cost of death report. Helping us navigate this somewhat confusing terrain are two women who've built their careers around talking about death in very different ways. Marianne Bowdler is a grief counsellor and clinical services manager at Griefline, who's worked extensively supporting marginalised communities through bereavement, attachment and loss. And Michelle Brasier is a comedian, writer and actor. Her frank and fearless brand of cabaret comedy has never made death funnier and has taken her all the way to Broadway. Marianne, Michelle, welcome to Life's Booming. James: What's Griefline? Who calls? Marianne: Griefline, we interpret grief very broadly. So grief is any response to a loss. So we lose lots of things, don't we? Might be, you see a house flooding down the river after a flood, could be redundancy, could be bankruptcy, might've lost your keys, the dog might've gone missing, so anything. James: Do people think to call you in that sort of thing? Marianne: More and more they do, more and more, and also ecological grief, which is that kind of nostalgia that we have for how the climate used to be. Michelle: Oh no. Right. Yeah, right. Marianne: And the landscape that was. And the beach that used to be at Byron. James: Yeah, so it's sort of an existential grief. Marianne: Grief is existential. James: Yeah, yeah. And then what, what can you offer? What happens when I call? Marianne: It's that annoying concept, isn't it? We hold space. It's about listening without judgment. And it's about enabling people to actually shine a torch into the darkness of the sorrow and the anguish that they might be experiencing. James: Yeah. Marianne: I mean, I think a lot of times you might be a young mom and you can't really be grieving because you've got to look after the kids. There's lots of times when you can't express your grief and it's quite helpful to be able to talk to a neutral third party who can be supportive. James: Yeah. There'd be cultural issues as well in some cases. Yes. And who's on the end of the line, like who's listening? Marianne: Our lovely band of volunteers. Yeah. So we have hundreds of volunteers and oftentimes it's someone who's been through a significant grief experience and therefore they know what it's like and they want to support somebody else. Or it might be students who are trying to learn something a bit beyond psychology, a bit more about existential things. James: Yeah. Michelle: Hmm. James: Michelle, you know about grief? Michelle: I know about grief. I'm an old hat at grief for such a young dog. I, yeah, I talk about this publicly all the time, but to do a little recap, we talk about this all the time. You and I, but I, my father was diagnosed when I was 18, with cancer and he died a week later. And shortly after that, my brother was diagnosed with a similar cancer and he died a few months later. And, I am now… assumed Lynch syndrome, which is a genetic… what's the word I'm looking for? Mutation. Yeah. Predisposition. It's a predisposition, to certain types of cancers. and so I'm always being poked and prodded and things, and getting things, you know, cut out, and early intervention, which is really lovely, but it means that grief has become a good friend of mine. And I make shows about all kinds of things, but one of my most successful shows, that you can watch on ABC iView that became my book, is called Average Bear. And it's about, it's about grief, but it's also about hope. And I don't necessarily subscribe to the idea that grief is always a bad thing. And I think that it's a really wonderful way through something in a really wonderful way to honour something. So I try to make shows that are funny about things that are sad. James: Yeah. What did you even know of grief? I mean, there you are, 18, 19 years old. I mean, I'm thinking of 18, 19-year-old me. I wouldn't have had a clue. I would never even know what it was. Michelle: I didn't know anything. I mean, I hadn't, my nan had passed away, but she'd had Alzheimer's for my whole life. And she died when I was quite young, oo I didn't really have any experience of grief except the dog. And even the dog, I had been told had gone to the farm, classic. James: Right. Michelle:And I truly thought that the dog had gone to the farm until I was about 26. And I went, Oh no! [laughter] But yeah, so I hadn't really had any, any life experience of grief. I hadn't really had any life experience at all. I mean, of course, I think, you know, it really hit me in the face. I had just gotten out of hospital myself cause I'd been in a fire, and had had third degree burns and had to learn to walk again. And I was surrounded by a lot of grief there, but I didn't know it was right around the corner for me. I saw people lose people all the time. And I was, you know, starting to wise up that maybe the world wasn't quite so simple, but when I lost my dad so fast, grief became a very fast, you know, friend and a big element of my life and something I was so interested in, because my friends weren't going through it. It was very strange. I think when you're young and you lose somebody. If you are the first one in your friendship group, it can be really isolating or you can choose to, you know, oh yeah. Make it a place of fun. Marianne: It’s like you joined a club you didn't want to… Michelle: …the Dead Dad Club, as I call it. Yeah, yeah. James: Yeah, yeah. But you had no prep for it. I mean, it'd be something if you had cancer for a few years.. Michelle:…Yeah. James: You know, you'd, you'd have a chance to talk to you your mother about it, everybody about it, start to realise this was going to happen. You know, it must have been just like some, it'd be like a disease itself, wouldn't it? Michelle: Well, it is. I mean, I think it just happens when it does happen so fast like that, it was an assault on the senses. And I have a chapter in my book that's called ‘the actual stages of grief’ because that's how I've experienced it. And I talk about how the world becomes small, like the world just closes in and you find yourself, you know, just assaulted by all these ideas and they don't feel real until you finally eat a piece of pizza again. And, you know, I think it, it was a really fast introduction into perspective and a really quick, life lesson in being curious and trying to open yourself up to as many experiences as you can because you don't know how long you have. And I mean, dad was just that, that was the canary in the coalmine. I didn't know it was going to lead to my brother and all the, you know, we didn't realise it was like a first domino. I was like, Oh, this is the bad thing that happens in my life. It didn't feel like a marker, but now it's very clear that that was the point where my life changed and continued to sort of tumble on down. But I'm still really grateful for, you know, the things that I've learned from grief and the way that I've learned to, to honour people. James: Yeah. Marianne, can we prepare for grief? I mean, is it something that, it should be something that's part of all of our lives that we think about what this might mean, or is it just something that you, you're going to have to experience it when it happens? Marianne: It's spectacularly unhelpful to say the dog's gone to the farm. James: Yes. [laughter] Michelle: Mum? Are you listening?! James: But I suppose that's not a bad place to start, is it? People often feel like having the guinea pig or the dog is a good way to teach children about death. Marianne: Exactly. And it's, how do you have those conversations? I think very little children are quite interested and curious about death because you find like a dead beetle or a dead bee and you're like: what is life that now has departed from this dead beetle or what have you. And it sort of disappears for a bit and then it comes back in the teenage years where you can get, you know, very emo and nihilistic and want to get skulls and crossbones tattooed. James: Grandma dies when you're a teenager. Marianne: …yeah… James: …That's not uncommon. That's about the age. Marianne: And I think it's more helpful now because we tend to take the children to the funeral. Whereas back in the day when children were really excluded from any of the processes around death, or even from going to visit grandma in hospital, we don't want your memory of her to be with all the tubes and what have you. And then it's just not real. And you try and explain to your young child and they're like, Yeah, yeah, I get it. I get it. But is she coming to my birthday? James: Yeah. Marianne: There's that sort of, you didn't quite get it. James: But I feel like that's, that's, that's learning about death, not necessarily about grief. Grief is what you're going to feel, that, you know, grief is the price we pay for love or grief is, you know, when you're still trying to love, but the person isn't there. Like those are the things you can't know that until it's your mum that dies or your wife that dies. Right. Marianne: Well, I think literature can help, we, you know, develop our empathy from reading, but really nothing prepares you till you go through it. Michelle: I think even the grief of losing a relationship can be really hard. Any grief, your first experience of grief, and I think it's just wonderful to have someone on the other side of it who can say, I went through it. Here's how it felt. Here's what the aftermath was like. Here's what it was like when all the flowers died and people stopped bringing lasagna and they forgot that I was grieving and they moved on. Here's what that pocket is like, and here's what it's like five years after. And here's what it's like 10 years after. And that's what I think the stories bring in value is going, Hey, it's fine. And here it is. And I survived and here's how. Day to day, here's how. I think that's really beautiful because I remember just going, how am I ever going to be okay? How is this going to be okay? And calling people that I knew that were older than me who had lost people and saying, can you just please tell me it's going to be okay and tell me why and tell me examples of how it's okay. Marianne: And then the only downside of that is that you can get this sort of narrative of this is the way to grieve. And then what we hear are many stories that people have different ways of grieving. James: Yeah. Marianne: Yeah. It's not, not everybody, like when I grieve, I kind of cry a river and then get a headache. James: Right. Marianne: Wish that weren't true, but that's, that's just it, but not everybody does that. James: Yeah. Yeah. Well, this was this, you know, Elizabeth Kübler Ross was very popular and talked about for many years with the seven stages of, of grieving, but there is no fixed… you might be angry for a minute, you might be angry for a week, you know, like there's nothing fixed about it, is it? The duration, neither the duration nor the order. Marianne: Exactly. And you might feel all the emotions all at the same time. James: Yeah. Yeah. Yeah. Michelle: Or none of them. Marianne: Or none of them. Michelle: And that's something that a lot of people don't talk about as well. James: Yeah. Michelle: You might feel just numb for quite a time, and that's okay. Like there's nothing wrong with that. It is, it is an interesting thing to go through, but such a beautiful and human thing. I mean, I love how we make meaning of things that aren't necessarily meaningful as, as people. And I think that's how we add value to our lives. And honour those who have died, but yeah… James: When you say that, what do you, do you mean we will make meaning out of; do you mean we're making meaning out of grief because grief is very meaningful, isn't it? Michelle: Well, just meaning out of the little things. So like taking control of your story, and I suppose this is my experience, but I always tell the story of my, when my father was dying and he had been diagnosed with cancer and I had just learned to walk again and got out of the hospital. And I had this feeling that I should go home to my country town where my dad lived. I was just like, I just feel like I should go. I feel like something's gone wrong because they'd said to us, there'll be another Christmas, which is another thing you go, okay, and that's a bargain. You go, okay, all right, great. I'll be at least another Christmas. And I had this feeling in the middle of the night that we weren't gonna get another Christmas, and then I, we weren't gonna get another 24 hours. And I got in the car and I drove, and my brother called me in the middle of the night and said, I've, you know, I've just gotten back to Wagga. We've booked you on the first flight. Dad's asking for you. He's not good. And I was like, you can cancel the flight, I'm in Albury, I'm an hour away. I just knew. And I'm not religious. I'm not, you know, I don't necessarily think I'm super spiritual or anything like that, but I make meaning where there is none in that I felt I had to be there. And so I was there. And when I say there is none, it's because I would have been on the first flight in the morning anyway, and I would have seen him and I would have got to say goodbye anyway. But there is so much beauty and poetry in driving through the night because I had a feeling and it could have meant nothing. It could, he could have not gone and he did. He went the next day. But that's where we put meaning, you know, as somebody who's not religious, I can see the value of religion and the value of faith and going, Well, I don't have necessarily religion or faith, but I have this meaning in stories, you know, it's that it's the meaning and then the humor that undercuts all that meaning. And I think that's what makes it human. And that's what makes it special. James: Yeah. Marianne, you know, perhaps we can only learn to grieve when it happens to us. We could learn, we could all learn to deal with other people's grief, right? As a society, are we well equipped with dealing with the grieving? Marianne: Kind of saying, no. James: Well, something we'll leave in question. Michelle: So polite of you. Marianne: Yes. Because our statutory bereavement leave is only two days. Michelle: Is it? Yeah. I don't have a real job, so I don't know these things. Marianne: Yeah. So that's not. Michelle: Two days? Marianne: Two days. And so workplaces struggle to know how to support people. We do trainings for like work, you know, how to support your colleagues, how to support the teammates, how to cope in the office. A lot of, there's a lot of interest because people just like, we don't know, we don't know how to support the team. James: So, you know, I'd struggle to know whether to say something or not. I didn't, probably don't want this mentioned in the workplace, but then I should have said something and then it's all too late. Michelle: But I don't think it's ever too late. And I think that it's the struggle that's about you. It's not about the person who's grieving and you can go to a person and just say, Hey, Would you like to talk about this, or would you like to leave it? That's not going to make a person cry, and if it is, they're so close to crying that they're going to cry anyway, and that's fine. There's nothing wrong with crying. We sort of want to just hold it. It's a Britishness in us, I think. We just want to hold these emotions in. I just think we can't treat people who are grieving, or who are dying for that matter, with cotton gloves, we can't, you know, and that's why I make these shows for people to come and laugh. And I have so many audience members who are actively dying and they come and they're like, tonight might be the night. Let's go. I was like, yes, like, let's have a laugh. If you only have 24 hours left, the least I can do is give you a laugh. Like, I think that we need to invite people into grief and into dying. And, you know, it's the problem with our society is that we go, Ooh, and, you know, people who are dying so often – and I'm sure maybe you even have this experience – but people get diagnosed with cancer and people just back off because they don't want to say the wrong thing. People aren't going to be upset with you for saying the wrong thing. They're going to be upset with you for disappearing in that tiny little period where they needed you the most. You'll get it wrong and that's fine. They'll tell you how to do it right. And you'll fix it like an adult, grow up. James: That is a fundamental thing, isn't it? We're too scared of getting it wrong. I'm sorry for your loss. Oh God. Was that terrible thing to say? Like maybe, maybe it is a terrible thing to say, but it's better than not saying anything. Marianne: Or, or in the workplace, where everybody's looking at the children's photos from the holiday and then the colleague whose child died. And the colleague will say, you know, I think about my child every moment of every day. It's not like you've done something to remind me. I'm fully aware. Michelle: Yeah. I know my kid is dead. Yeah. I don't need you to remind me. I know. It's okay. I already know. Marianne: And the best things you can just say is, I've got your back. James: Mm. But I suppose this is the kind of thing we could all help one another with, isn't it? Yeah. This, this could, we could be, we could all be a little more instructed in this. Marianne: And I think there were, perhaps if you look at the like English, Victorian tradition, it's like now they're wearing black. Now they've got a little bit of purple. Now they've got jet jewelry. There were all these signifiers that let us know how far, you know, how long ago the mourning process started, we don't know anything, we can't tell by looking at a person, what happened last week, what happened 10 years ago. Michelle: yeah. James: Does humor help? Marianne: Absolutely. We would look at the distress, if you're just going to go a bit sciencey, the distress that you experience in grief is called situational distress. You know, a thing happened, then you got distressed. And part of that would be a very low mood, for example. If you do nothing to break the low mood, that can run into depression and that can run into a major depressive But the best thing that will kind of, it doesn't take away the distress exactly, but it ruptures that, is comedy, is having a laugh, because it alleviates the mood, it alleviates the tension, you feel more connected and certainly in a comedy show, you just feel connected to everybody else in the room. Michelle:Yeah. James: And you, you went, I mean, you went to it – it is you, isn't it? I mean, I'm the same. I tend to talk in humor. You know, that's my tone. My predominant tone is to try and be funny. And so therefore, whatever happens, you know, I had cancer. I was automatically making jokes about it. I still do, you know. So you, but is it more than that? Is it more than just your way of speaking, your way of being? Michelle: I think it, yeah, I think it is, you know, that second nature. You can't, if you're a clown, you're a clown, you can't turn it off and you shouldn't turn it off unless you want to. But I also, back on the sciencey stuff, you know, there, there is such a similar physiological response that we have to crying as we do when we're laughing or when we're singing. It's just, it's our release, it's, you know, all this vagus nerve stuff, just getting it out. A release is so valuable. And if that release can be laughter, you're not going to get a headache, as quickly as you will with the, with the tears and show it, maybe it comes along with the tears and maybe they're, they need to be friends and they need to, you know, be together. Um, and you know… Marianne: …it's the catharsis Michelle: It's the catharsis and we need it as, as animals, we need it. So I think that's why it's so… James: It's also the truth as well. Like, I think, you know, some of the best laughs you'll have is at a funeral. Michelle: Oh my God, yeah. James: Because you will tell each other truths about the person and about your relationship to them, and somebody will start telling you a story and you'll go, Oh my God, they never told the story like that. You know, like… Michelle: …Yes, exactly. James:…All those sort of things. It's fantastic, you know. It's the, you know, humour is often truth telling. Michelle: And the reason it's so funny is because it breaks the tension of this wild ritual of funerals that we have, that is, it doesn't really suit us as a society. It's somebody speaking on a microphone that doesn't really work and they don't know how to use the microphone. They're making a speech. They're not a good speech writer. They shouldn't be making a speech. Somebody else should be making a speech. It's never going well. And that's kind of funny. My dad's funeral was excellent. He went, he'd made, we'd made this playlist of his favorite songs for him to be carried out of the church too. Unfortunately, there was like a bit of a mix up and that playlist didn't play when he was carried out of the church. It played as he was lowered into the ground in the cemetery, which would have been fine had the first song not been ‘Ring of Fire’ by Johnny Cash. And it was the funniest thing that's ever happened in my family was in hysterics. Everybody else taking it very seriously. Didn't know what to do. Didn't know how to touch it, trying to keep it away. But the rest of us, the ones who really, really knew him and really loved him were in there having a laugh because it was like, this is absurd. James: He would have loved it. Michelle: He would have loved it. And death is absurd. And so is life, and that's fine. You know, I think we just need to go gentle with ourselves and with the people that we're trying to help, but gentle with ourselves in our own approach to it, you know, let yourself have a laugh, you deserve it, it's hard. James: Yeah. I sometimes think that death is the ultimate joke because we, we live like it's never going to happen. So here’s, all of us live every single day as though we are never going to die. How do you think people react to you, you know, like, I'm thinking of, you know, ‘Lasagna won't bring back my dead dad’, your famous song about the fact that, you know, while grieving you'll get a lot of, a lot of lasagna. Michelle: Yeah. James: How do people react? Like, have you had people just go, this is too much, I can't, I can't deal with this. Michelle: I've never had that reaction. And I've done the show so many times, people have watched it on TV and I've never gotten a DM saying this is rude or this is wrong, you know, disrespectful. It's always the people in the show, like the people who have grieved that think it's the funniest. I even say after I do the song in the show, I say if somebody next to you is laughing quite loudly at that, I'd like you to turn to them and say sorry for your loss.. James: Yeah. Michelle: Because that's, you know, it is, it's universal. It's so universal. Yeah. so no, I've never had somebody complain about me not taking death seriously enough. James: Has it helped you? Michelle: Yeah! James: Yeah. Michelle: If I didn't have humor, if I took myself seriously, I would be terrified every moment. I'm already terrified. Look at the news. Yeah. You know. Marianne: Don't look at the news. Michelle: Yeah. Sorry. That was bad advice. Don't look at the news. but do vote well. but I just think, you know. I don't know who I would be if I, if I took things seriously, if I took myself seriously, I would have such a difficult time and I'm already stressed about every lump and bump. And you know, it's, it's really scary. I'm scared of dying, but it means that I think I live my life like I am going to die tomorrow. And I, that's the gift that I've been given by grief, but I also… James: …and by your own diagnosis, I mean, we should just emphasise that again, you are living with the threat that the same thing that happened to your brother and father can happen to you. Michelle: Yes, exactly. And I think knowing that – even though everyone could be hit by a bus tomorrow and it really doesn't make me any more likely than anyone else at the end of the day – but it's a gift, it's a gift, the gift of perspective of knowing that like, you're only here for a short time, so you might as well make it a good time. And that's true of anyone. It doesn't matter if you live to a hundred, it's probably still going to feel short. Well, if you're lucky it’ll feel short. James: But that's, I mean, we kind of know that, but we don't really live like that, do we Marianne? Marianne: We don't, but there's good reason to think that we should. In the world of grief literature, we talk about the loss of the assumptive world. James: The assumptive world. Marianne: The assumptive world. As a child, we assumed it would always be a Sunday afternoon and we'd go home and have Tim Tams. And everything would be the same day after day. And then the first time you sort of meet death, it's like the rug’s been pulled out from under you and you can't assume that anymore. And then suddenly you're unsafe and you panic. But I think what's a curious moment for all of us was the pandemic gave the whole world and everybody, we all collectively lost the assumptive world at the same time. So now we're sort of on shakier ground. but when we come back to just each and every one of us, yes, I think it's helpful to understand that we are mortal. James: Yeah. Marianne: And when you get your head around that. Then you can, I think, fully be present in the moment and enjoy things. James: But that's always what a lot of people will say about the pandemic years is perhaps, particularly that first year, particularly if you weren't in Melbourne, but particularly that first year was sort of like, isn't this great? We're all living this together. We are all now understanding that we're very mortal and can be threatened. Oh my Lord, our governments are all working together, but it almost seems it's like, as soon as we could get over that and forget all that, we did. Marianne: Yeah, we did. Michelle: You know, I think we just, we're looking for someone to blame. I mean, not to get into that sort of existential divided society crisis that we're in currently, don't look at the news, but, yeah, COVID was interesting to see how people reacted to it, and the grief. I talk about this in my book as well. I say, I was born at the end of history because I was a 90s kid and they were calling it the end of history. They were like, the war is done. The wars are done. We're done doing the wars. We're doing peace now. We're smarter than that. We've sorted it out and you can be whatever you want to be. And this is before we knew my generation wasn't going to be able to afford a house. And we really were promised… and it's why I've been successful in my career. Cause my parents were like, yeah, I guess you can do whatever you want now. That's what they're saying. And I was like, well, I believe you, which I'm lucky I did and sort of followed my nose to where I've gotten. But I think there is an enormous amount of collective grief in every generation, but I think it really, like, hits my generation very hard because we, we can't believe we were lied to, like, you know! And I think we were feeling that, and then COVID came and I think everyone sort of started to feel that, but I mean everyone's different, has their own set of circumstances and I'm speaking very generally, but it is difficult. Marianne: But across the board, anxiety went up, especially of your generation. And some people would think that what lies underneath all anxiety is death anxiety. Michelle: Yeah. Yeah. I think that's true. I think that's really true. It's definitely my main anxiety, you know. James: Yeah. You know, we've been talking about grief as, you know, it's, it's something I suppose we probably always sort of these sort of emotions as something that define us, define humanity. That's what makes us human. We've had all those stories of sort of like elephants grieving and things, haven't we? Marianne: Yeah, absolutely. Or, and you see it with your pets as well, they'll go searching for the person who's not there. Michelle: Yeah, you should let your dog sniff a dead person, or the other dead dog. You should do that so they know what's happened. James: Yeah, yeah. Marianne: And last year I read that blue tongued lizards grieve, which I'm still very touched by that. Michelle: It's beautiful. Marianne: Yeah. It was a lizard was trapped on a fence and died and the mate just stayed with it for I think three or four days. James: Wow. Yeah. Yeah. So everything does. Marianne: So not just mammals. James: Yeah, not just mammals, the cold-blooded ones do, too. Michelle: That's beautiful. Do you think mosquitoes are grieving? James: Oh, totally. Michelle: Got a lot to apologise for. James: Yeah, that's right. So, when you whack one, just go, sorry. Michelle: I know. I'm sorry. Sorry for your loss.. James: That's really sad. Marianne: That should cover it. Michelle: That should sort it. James: Marianne, thank you so much. Marianne: Thank you. Lovely conversation. Michelle, lovely. Thank you. Michelle: Thank you so much. James: Well, thanks to our guests, Marianne Bowdler and Michelle Brasier. You've been listening to season six of Life's Booming, Dying to Know, brought to you by Australian Seniors. Please leave a review or tell someone about it. Head to seniors.com.au/podcast for more episodes. May your life be booming. I'm James Valentine.See omnystudio.com/listener for privacy information.

BUFFALO, NY - December 30, 2024 – A new #editorial was #published in Oncotarget's Volume 15 on December 24, 2024, titled “Pitfalls and perils from FDA-approved germ-line cancer predisposition tests." Authored by Dr. Wafik S. El-Deiry, Editor-in-Chief of Oncotarget, and Dr. Eli Y. Adashi from Brown University, the article highlights concerns about the risks of a newly approved genetic test for cancer risk. This test, called the “Invitae Common Hereditary Cancers Panel," was approved in 2023 and examines 48 genes linked to inherited cancers, including breast, ovarian, and Lynch syndrome-related cancers. Although the test increases access to genetic information, the authors warn that using it without professional guidance may lead to confusion, stress, and potential harm. One concern is that people can order this test online without consulting healthcare professionals or genetic counselors. Without expert help, users might struggle to understand their results especially if they indicate risks that are unclear or difficult to act on. This can cause unnecessary anxiety and confusion. “The DTC option of germ-line testing for cancer susceptibility should be discouraged given the risks of anxiety, lack of adequate interpretation for variants not strongly associated with cancer, potential for minors to be tested outside the healthcare system and potential for loss of follow-up if test results are not shared with health care professionals or never make it into the medical record.” The editorial also points out ethical and medical issues when minors use these tests. If a child's test is done without medical oversight, results might not be added to their health records, making follow-up care harder to manage and potentially risking their long-term health. Cost is another issue. These tests are often not covered by insurance, which can place a financial burden on families who might need additional testing or medical advice. The researchers emphasize that genetic testing for cancer risk should always include healthcare providers and genetic counseling. This ensures users fully understand their results and receive proper guidance. The authors also call on the US Food and Drug Administration (FDA) to provide clear rules for using these tests, particularly for minors. In conclusion, while genetic testing holds great potential for improving cancer prevention and care, its benefits must not come at the cost of safety and public health. Responsible use of these tests will require collaboration between regulators, healthcare professionals, and testing companies to address the risks and ensure these tools are used effectively. DOI - https://doi.org/10.18632/oncotarget.28677 Correspondence to - Wafik S. El-Deiry - wafik@brown.edu Video short - https://www.youtube.com/watch?v=DjKpiBNDWHo Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Cindy, a guest on the LDN radio show, shared her remarkable health journey. She described experiencing hypermobility from a very young age and enduring a multitude of health challenges, including menstrual issues, pots, and food allergies. Her difficult pregnancies and the revelation of her genetic predisposition to certain conditions shed light on the intricate genetic component of her health issues. Through her story, she emphasized the complexities of managing multiple health conditions and underscored the significance of comprehending the genetic factors at play in her health struggles.

Radio Free Galisteo's John Shannon speaks with Bob Forrest, the "Ambassador" for DNA4ADDICTION.COM, an organizatrion that has developed a DNA testing kit that provides insights into an individual's genetic predisposition to opioid addiction.  Forrest is known as the straight-talking counselor on VH1's Celebrity Rehab with Dr Drew. Bob was the clinical director and on the board of the Musicians Assistance Program/MusiCares, and he spent 8 years counseling at Las Encinas Hospital in Pasadena. Prior to his life in recovery, Bob was best known as a musician, fronting the critically acclaimed Los Angeles bands: Thelonious Monster and The Bicycle Thief. Bob was heavily acclaimed for his gifts as a songwriter, and frontman. He is a fierce recovery advocate and a legend in the music industry.  DNA 4 Addiction Website:  https://dna4addiction.com/Bob's Website: https://www.rehab-bob.com/Support the showFollow Radio Free Galisteo on Instagram at: @radiofreegalisteo. We're on twitter here: https://twitter.com/FreeGalisteo or @FreeGalisteo. We're now on BLUESKY: https://bsky.app/profile/radiofreegalisteo.bsky.social Support the show by going to https://www.RadioFreeGalisteo.com and clicking on our Red DONATE button to select a method of financial encouragement - Patreon, Paypal, Stripe or just Buy Us a Coffee!

The conversation covers various topics, including Bob Forrest's experience as a CNN contributor, the impact of social media, and drug addiction in the music industry. Bob shares insights on the 80s drug culture in Los Angeles, highlighting connections between bands like Motley Crue, Aerosmith, and the Chili Peppers. They discuss the challenges of maintaining sobriety and the role of drugs in the music scene. The discussion also touches on the evolving nature of music, the decline of meaningful lyrics, and the impact of social media on society. Additionally, they reflect on the personal and professional struggles of maintaining a career in music and the importance of songwriting.0:00:00 - Intro0:00:13 - CNN Contributor & Social Media Impact0:02:18 - Musical Connections & Drug Culture0:05:23 - Heavy Metal Vs Indie Rock Perceptions 0:10:22 - Reflections on Kurt Cobain & Indie Rock0:14:34 - The Role of Social Media & Personal Boundaries0:14:47 - The Impact of Pharmaceutical Industry on Addiction0:19:33 - Social Media & Problems with Humanity 0:34:10 - Doing Drugs & Adverse Consequences & Music 0:56:09 - The Struggle with Addiction & Path to Recovery1:00:26 - The Role of Bands & Ebb & Flow of Success1:08:49 - Drugs, Sobriety, Songwriting & Catharsis 1:21:18 - Psychedelics & Other Drugs & Addiction 1:26:35 - Genetic Test & Predisposition to Addiction 1:35:10 - Kids, Society, Rules and Culture 1:53:13 - Outro Bob Forrest website:https://bobforrestmusic.com/Oro House Recovery Centers website:https://www.ororecovery.com/bob-forrest/Chuck Shute link tree:https://linktr.ee/chuck_shuteSupport the showThanks for Listening & Shute for the Moon!

One instance of grief can be difficult enough to cope with, but for Lawrence Ingrassia, losing multiple family members was not only devastating but perplexing. Typical discussions surrounding inheritance may include heirlooms or estates — not rare tumors in the cheeks of toddlers, as was the case for Ingrassia's two-year-old nephew. After he lost his mother, two sisters, brother, and nephew to different types of cancer, Ingrassia was unsure whether his family's generational heartbreak was merely misfortune or if there was some other cause. In his book A Fatal Inheritance: How a Family Misfortune Revealed a Deadly Medical Mystery, Ingrassia weaves his own family history with a history of cancer research. Part memoir, part medical thriller, Ingrassia's work begins in the 1960s with Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr., groundbreaking researchers and physicians who would later uncover links between genetics and cancer. A Fatal Inheritance journeys from the early days of discovery to present-day developments decades later, as Ingrassia and others continue to build upon Li and Fraumeni's initial investigations and discover what this means for themselves and their families. Ingrassia also looks toward the future, as gene sequencing, screening protocols, CRISPR gene editing, and other developing technologies aid in extending lifespans and possibly getting us closer to a cure. Lawrence Ingrassia is a former business and economics editor and deputy managing editor at the New York Times, having previously spent twenty-five years at the Wall Street Journal, as Boston bureau chief, London bureau chief, money and investing editor, and assistant managing editor. He also served as managing editor of the Los Angeles Times. The coverage he directed won five Pulitzer Prizes as well as Gerald Loeb Awards and George Polk Awards. His first book, Billion Dollar Brand Club, chronicles the rise of popular direct-to-consumer e-commerce brands and was shortlisted for several best business book awards for 2020. His latest book, A Fatal Inheritance, narrates the tale of a team of dedicated researchers who solved the medical mystery behind seemingly unrelated cancers devastating his and other families. Robert W. Merry spent 45 years in Washington, D.C., as Wall Street Journal reporter and executive at Congressional Quarterly, including 12 years as CQ's president and editor-in-chief. After CQ was sold to the Economist, he also served as editor of the polemical magazines The National Interest and The American Conservative. He is the author of six books on American history and foreign policy, including the forthcoming Decade of Disunion: How Massachusetts and South Carolina Led the Way to Civil War, 1849-1861 (Simon & Schuster). Buy the Book A Fatal Inheritance: How a Family Misfortune Revealed a Deadly Medical Mystery Third Place Books

Multiple Onychopapillomas and BAP1 Tumor Predisposition Syndrome.Optimizing Intralesional Triamcinolone Acetonide Treatment for Isolated Nail Psoriasis: A Pilot, Intra-subject randomized controlled trial.

David Gillespie shares how to reset our brain from chronic stress, dopamine overstimulation, and addiction. David is a father of six and bestselling author on important health topics. His first book, Sweet Poison, is credited with starting the anti-sugar movement. Sponsor: In-15 compact insulin testing https://metabolica.bio Books: Sweet Poison; Toxic Oil - Why Vegetable Oils Will Kill You; Big Fat Health Lies; Eat Real Food.Teen Brain and the Brain Reset 2:00 Who David writes for 4:00 What is going on in the teenage brain 8:00 Teenage brain engineered for addiction 13:00 Alcohol is especially dangerous for teen brains 13:00 Apps are designed to be addictive 14:00 Predisposition to addiction in the brain 19:00 Teen girls' addictions present differently 29:00 Action parents can take 31:00 How to help a child or teen withdraw from screens 36:00 Daryl Edwards movement expert https://youtu.be/PKaRZ_m-q6U?si=H6jkOv0Hd9BPMSil 37:00 ADHD causes and the damaging solutions 40:00 Screens and devices are addictive 43:00 Dr. Rod Taylor Low Carb Down Under support of Sweet Poison book46:00 Sugar harmful 47:00 Fructose danger 50:00 Sugars in common family foods 51:00 Low-fat foods full of sugar 55:00 Seeds oils "extremely dangerous" creating precursors to cancer56:00 Food link to childhood cancer 1:04:00 Old fashioned recipes 1:02:00 dietician pushback 1:10:00 Binning cancer sunscreens Family Health Lab Podcast: Game Changers S1: E35 Host: Claire McDonnell Liu, Nutritionist, https://leafie.com/ https://www.facebook.com/leafiehealth Sponsor: In-15 compact insulin testing https://metabolica.bio IMPORTANT - The content in this video is not a substitute for medical advice. Always consult with your physician regarding your health matters. Individuals' lifestyles, bodies and health histories vary. The author does not assume any liability to any party for any loss, damage, or disruption caused by the choice to implement any of the health strategies included.

A bit of a different episode compared to my other episodes - after having taken a break due to health reasons, I'm back with a little update on how I'm doing, medical stuff, and a little insight into restrictive 'medical diets' as someone who has recovered from an eating disorder. Do you feel like you need more help recovering from your eating disorder? Whether you struggle with anorexia, bulimia, OSFED, or other (un)diagnosed disordered eating issues, I'm here to help! I've started my 1-on-1 coaching back up, and I'm fully booked at the moment, but spots may be opening up in July, so be sure to put yourself on the waitinglist, and I've got an exciting new program launching soon! Feel free to take a look at my ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and sign-up or ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠contact me⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. You can also always DM me on ⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠! If you have any questions that you would like me to answer on the podcast, you can fill out ⁠the form⁠ on my website. Would you like my advice 'on paper', create your own plan of action, and join our Facebook support group? Check out my ⁠⁠⁠⁠⁠⁠guide⁠⁠⁠⁠⁠⁠!

The notion that some individuals possess a genetic predisposition to perceive the imperceptible, or that childhood exposure to esoteric concepts could unlock hidden potentials, challenges our understanding of human consciousness. The possibility that Earth's own energetic grid might facilitate contact with other realities seems almost too fantastic to consider...If you are having a mental health crisis and need immediate help please go to https://troubledminds.org/help/ and call somebody right now. Reaching out for support is a sign of strength.LIVE ON Digital Radio! http://bit.ly/3m2Wxom or http://bit.ly/40KBtlWhttp://www.troubledminds.org Support The Show!https://www.spreaker.com/podcast/troubled-minds-radio--4953916/supporthttps://ko-fi.com/troubledmindshttps://rokfin.com/creator/troubledmindshttps://patreon.com/troubledmindshttps://www.buymeacoffee.com/troubledmindshttps://troubledfans.comFriends of Troubled Minds! - https://troubledminds.org/friendsShow Schedule Sun-Mon-Tues-Wed-Thurs 7-10pstiTunes - https://apple.co/2zZ4hx6Spotify - https://spoti.fi/2UgyzqMTuneIn - https://bit.ly/2FZOErSTwitter - https://bit.ly/2CYB71U----------------------------------------https://troubledminds.substack.com/p/the-super-experiencer-predispositionhttps://thedebrief.org/study-finds-ufo-witnesses-may-have-personality-traits-that-increase-likelihood-of-sightings/https://www.reddit.com/r/Experiencers/comments/vlfwsk/a_big_picture_perspective_on_ufo_phenomena/https://en.wikipedia.org/wiki/Alien_abduction_claimantshttps://solarchariot.medium.com/ufo-experiencer-support-groups-6e51eb2a4566https://www.insideedition.com/starborn-inside-the-support-group-for-people-whove-had-alien-encounters-47901https://www.dailymail.co.uk/sciencetech/article-12316755/Im-UFO-experiencer-visited-creatures-red-eyes-glowing-orbs-stories-compelling-NASA-CIA-studying-me.htmlhttps://www.psychologytoday.com/us/blog/is-america/201902/taking-ufos-seriouslyhttps://www.psychologytoday.com/us/blog/is-america/201902/taking-ufos-seriouslyhttps://www.metabunk.org/threads/major-ufo-experiences-are-specific-to-the-observer.13027/https://www.mindbodygreen.com/articles/learning-to-look-past-our-imprints-for-more-mindful-lifehttps://www.historynewsnetwork.org/article/how-did-childhood-folklore-spread-before-the-interhttps://www.tandfonline.com/doi/full/10.1080/09669760.2017.1287062

In today's episode of the Balancing Chaos Podcast, Kelley sits down with social media personality, entrepreneur and author Bruce Brackett. Originally from southwest Montana, Bruce moved to New York at the age of 18 to pursue his dreams of being on Broadway. After many distractions, making it to Off-Broadway, and developing several addictions from alcohol to meth, Bruce found his true calling and his way back to sobriety through art and by advocating for recovery to his online audience of over 1.2 million people. This online community of recovery fuels his love, passion, creativity, and mission to share positivity and the possibilities of recovery.Through their conversation, Kelley and Bruce delve into Bruce's personal story and the topic of addiction in general. The two discuss how addiction does not discriminate and how addiction can affect anyone regardless of background, the various reasons people may turn to addiction, and the journey from struggle to recovery and success. This episode sheds light on the intricate connection between addiction recovery and mental health. The journey of recovery often involves confronting deep-rooted feelings of loneliness, trauma, and the need for escape. Whether you're struggling in silence or you know someone who is struggling, this episode offers an immense amount of insight and hope and teaches us about the triggers for addiction, how to self-forgive, what to do if you're a family member of someone going through addiction and so much more. To connect with Kelley click HERETo book a lab review click HERETo connect with Bruce click HERETo get Bruces Book - How to Breathe While Suffocating click HERE 

In this week's episode, I'm snorkelling through a few things I'm watching and enjoying, I'll be sharing my thoughts on a viral clip featuring Oprah and a panel discussing weight loss, calories, and obesity. Additionally, I'll touch on the Andrew Huberman article and the backlash it's stirred up. And of course, I'll be answering some listener questions!1. Best way to get back to maintenance calories after being in a deficit for 10 months and losing close to 40lbs? 2. Any options for high protein breakfast, it's my biggest struggle!3. How do you approach fat loss when you know your genetics are working against you? Just accept that it'll be harder? Assume I'll be eating poverty calories all my life? 4. Can you turn body fat into muscle without a calorie deficit?truLOCAL sponsor Natura market discount: ALICIA10 for 10% off your first order of $59.00 or more!Support the showInterested in working together? Here's how I can help:fill out my application form Body recomposition: Sustainable fat loss--for good. If you feel like you want personalized support in taking the final steps towards improving your relationship with food and your body, I am here to provide one-on-one guidance. This may be especially helpful if you have already been working on this for some time and are looking for additional support to make further progress. Establishing and focusing on healthy habits (movement, nutrition, sleep, stress management), and/or Finding a balanced, flexible, & sustainable approach to achieving your body goals, then I'd love to connect: info@wellnesswithalicia.com OR fill out my application form. Send me a DM on Instagram: @aliciamayconnorsCheck out my Website: www.wellnesswithalicia.comCheck back every week for a NEW episode! Currently available on Spotify, ...

In this episode of Deep Dive For Impact, Nick discusses several best practices that an organization can utilize when preparing to make a fundraising ask. We go over two "pre-best practices" during the preparation stage before discussing the five best practices during the actual ask process. Finally, we conclude with a stepwise mental model that allows us to view the ask as a sequence rather than as a one-time event. 0:00-2:04 Introduction 2:04-3:51 "Pre-best practice" #1: Have a goal of getting to the ask 3:51-5:49 "Pre-best practice" #2: Predisposition 5:49-10:07 Best practice #1: Use a visual 10:07-13:03 Best practice #2: Have a "funding rationale" 13:03-15:22 Best practice #3: Prepare and practice the flow of the visit (including transitions) 15:22-15:44 Best practice #4: Think about possible questions and objections 15:44-19:30 Best practice #5: Think about the ask as a dialogue 19:30-24:21 Mental model: The ask as a sequence 24:21-24:44 Conclusion

BUFFALO, NY- November 22, 2023 – A new #research paper was #published in Oncotarget's Volume 14 on October 4, 2023, entitled, “Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity.” Breast cancer (BC) is the most common type of cancer among women in Kazakhstan. To date, little data are available on the spectrum of genetic variation in Kazakh women with BC. In this new study, researchers Gulnur Zhunussova, Nazgul Omarbayeva, Dilyara Kaidarova, Saltanat Abdikerim, Natalya Mit, Ilya Kisselev, Kanagat Yergali, Aigul Zhunussova, Tatyana Goncharova, Aliya Abdrakhmanova, and Leyla Djansugurova from the Institute of Genetics and Physiology, Kazakh Institute of Oncology and Radiology, Al-Farabi Kazakh National University, and Asfendiyarov Kazakh National Medical University aimed to identify population-specific genetic markers associated with the risk of developing early-onset BC and test their association with clinical and prognostic factors. “To our knowledge, this is the first study using NGS [next-generation sequencing] technology to study the genetic predisposition to early-onset BC women from Kazakhstan and assess their impact on the patients' clinical outcomes.” The study included 224 Kazakh women diagnosed with BC (≤40 age). Entire coding regions (>1700 exons) and the flanking noncoding regions of 94 cancer-associated genes were sequenced from blood DNA using MiSeq platform. The researchers identified 38 unique pathogenic variants (PVs) in 13 different cancer-predisposing genes among 57 patients (25.4%), of which 6 variants were novel. In total, 12 of the 38 distinct PVs were detected recurrently, including BRCA1 c.5266dup, c.5278-2del, and c.2T>C, and BRCA2 c.9409dup and c.9253del that may be founder in this population. BRCA1 carriers were significantly more likely to develop triple-negative BC (OR = 6.61, 95% CI 2.44–17.91, p = 0.0002) and have family history of BC (OR = 3.17, 95% CI 1.14–8.76, p = 0.03) compared to non-carriers. “This study allowed the identification of PVs specific to early-onset BC, which may be used as a foundation to develop regional expertise and diagnostic tools for early detection of BC in young Kazakh women.” DOI - https://doi.org/10.18632/oncotarget.28518 Correspondence to - Gulnur Zhunussova - gulnur_j@outlook.com, and Nazgul Omarbayeva - nomarbayeva1@gmail.com Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28518 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, breast cancer, early-onset breast cancer, triple negative breast cancer, next-generation sequencing, pathogenic variant, Kazakh population About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: SoundCloud - https://soundcloud.com/oncotarget Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Media Contact MEDIA@IMPACTJOURNALS.COM 18009220957

In this illuminating episode of the Functional Fertility podcast, Dr. Kalea Wattles engages in a captivating conversation with Dr. Robyn Murphy, shedding light on the multifaceted world of the microbiome and its profound impact on fertility and reproductive health. They embark on an exploration of the microbiome's role in both the gut and the reproductive tract, unveiling its significance in the conception process and the maintenance of pregnancy. Dr. Murphy delves into the pivotal factors influencing the composition of our microbiome and shares invaluable insights into recognizing when it might contribute to fertility challenges. The episode takes a compassionate look at pregnancy loss and its relationship with the microbiome, offering tried-and-true methods for nurturing robust lactobacilli. Dr. Murphy also uncovers the connections between the microbiome, immune system health, and opportunistic infections. Chronic infections in the urogenital and gastrointestinal realms are discussed, alongside the intriguing link between the gut microbiota and conditions such as PCOS and endometriosis. Dr. Murphy's expertise extends to the genetic dimension, where she explores how genetics can impact our microbiome and offers guidance on assessing this aspect of our health. This episode is a treasure trove of knowledge, providing a holistic perspective on microbiome health and its profound influence on fertility and reproductive well-being

Marketing scientists have discovered that if we push through uncomfortably high ad impression frequency — even if that generates short-term negative feelings — the consumer will eventually warm up to the brand. Tod interviews the paper author..

In today's episode, Dr. Ken Berry talks about the distinctions in how fat storage patterns evolve in individuals of both genders during puberty.

In this week's episode, we'll discuss pembrolizumab after autologous stem cell transplantation in patients with peripheral T-cell lymphoma. Newly reported phase 2 study results show that blocking PD-1 with pembrolizumab had a favorable safety profile and demonstrated promising activity, supporting further confirmatory studies in this setting; germline genetic predisposition to myeloid neoplasms in patients with hypoplastic bone marrow. Researchers report mutations that are significantly associated with cytopenias in adulthood in these patients. And pathogenic or likely pathogenic variants were linked to severe cytopenias and advanced myeloid malignancies; and finally, if monocytes and their descendants are less plastic than previously thought. Investigators have identified four functionally specialized monocyte subsets that derive from specific myeloid progenitor lineages. They show that the fate of these monocyte subsets is epigenetically scripted, with little flexibility after differentiation begins, even under conditions of stress.

In today's episode, Gina discusses the relatively common anxiety symptom of dissociation and how to better cope with this distressing experience. Dissociation and derealization are not limited as symptoms to anxiety disorders but occur with other mental health conditions as well, such as depression. Learn that dissociation is not dangerous and comfort yourself that it will pass and it is not a sign of some severe mental pathology.Please visit our Sponsor Page to find all the links and codes for our awesome sponsors!https://www.theanxietycoachespodcast.com/sponsors/Thank you for supporting The Anxiety Coaches Podcast.Find even more peace and calm with our Supercast premium access membership! https://anxietycoaches.supercast.com/Here's what's included for $5/month:❤ New Ad-Free episodes every Sunday and Wednesday❤ Access to the entire Ad-free back-catalog with over 600 episodes❤ Premium meditations recorded with you in mind❤ And more fun surprises along the way!All this in your favorite podcast app!To learn more go to:https://www.theanxietycoachespodcast.comJoin our Group Coaching Full or Mini Membership Program Learn more about our One-on-One CoachingWhat is anxiety?Quote:Healing may not be so much about getting better, as about letting go of everything that isn't you – all of the expectations, all of the beliefs – and becoming who you are.–Rachel Naomi RemenChapters0:00:48 Coping with Overwhelming Emotions: Dissociation Explained0:02:02 Causes of Dissociation: Trauma, Childhood Experiences, Attachment Disruptions0:04:38 Biological Factors and Predisposition to Dissociative Disorders0:05:35 Understanding Dissociation as a Coping Mechanism0:07:45 Common Symptoms of Dissociation0:13:19 Dissociation and its Connection to Mental Health IssuesSummaryIn today's episode, we delve into the topic of dissociation as a coping mechanism for overwhelming emotions. Dissociation is not exclusive to individuals diagnosed with dissociative disorders - it can occur in anyone facing highly emotionally overwhelming situations. Trauma, especially childhood trauma like abuse or neglect, is a primary cause of dissociation. Other factors such as adverse childhood experiences, attachment disruptions, biological factors, and cultural/societal factors can also contribute to dissociation.Dissociation serves as a way for individuals to cope with overwhelming emotions by mentally disconnecting or escaping from distressing situations. It often co-occurs with other mental health conditions such as PTSD, depression, anxiety, and substance abuse. Recognizing the common symptoms of dissociation, such as memory loss, distorted perception, and a sense of unreality, is crucial. Understanding these symptoms helps individuals evaluate whether they still rely on dissociation when it is no longer necessary.Sometimes, people may experience a distorted sense of reality or a feeling of unreality in their surroundings. However, it is important not to add fear to these experiences but rather approach them with curiosity. Keeping a journal and discussing these perceptions with a therapist or coach can provide insights and understanding. Feeling detached from oneself, emotions, or having a blurred sense of identity can also be signs of dissociation. These symptoms are often present when individuals are coming out of an anxious or panic state. Inability to cope with emotional or professional stress is another indicator of dissociation, as individuals feel disconnected and unable to handle such challenges. Learn more about your ad choices. Visit megaphone.fm/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In today's episode, Gina discusses the relatively common anxiety symptom of dissociation and how to better cope with this distressing experience. Dissociation and derealization are not limited as symptoms to anxiety disorders but occur with other mental health conditions as well, such as depression. Learn that dissociation is not dangerous and comfort yourself that it will pass and it is not a sign of some severe mental pathology. Please visit our Sponsor Page to find all the links and codes for our awesome sponsors! https://www.theanxietycoachespodcast.com/sponsors/ Thank you for supporting The Anxiety Coaches Podcast. Find even more peace and calm with our Supercast premium access membership! https://anxietycoaches.supercast.com/ Here's what's included for $5/month: ❤ New Ad-Free episodes every Sunday and Wednesday ❤ Access to the entire Ad-free back-catalog with over 600 episodes ❤ Premium meditations recorded with you in mind ❤ And more fun surprises along the way! All this in your favorite podcast app! To learn more go to: https://www.theanxietycoachespodcast.com Join our Group Coaching Full or Mini Membership Program  Learn more about our One-on-One Coaching What is anxiety? Quote: Healing may not be so much about getting better, as about letting go of everything that isn't you – all of the expectations, all of the beliefs – and becoming who you are. –Rachel Naomi Remen Chapters 0:00:48 Coping with Overwhelming Emotions: Dissociation Explained 0:02:02 Causes of Dissociation: Trauma, Childhood Experiences, Attachment Disruptions 0:04:38 Biological Factors and Predisposition to Dissociative Disorders 0:05:35 Understanding Dissociation as a Coping Mechanism 0:07:45 Common Symptoms of Dissociation 0:13:19 Dissociation and its Connection to Mental Health Issues Summary In today's episode, we delve into the topic of dissociation as a coping mechanism for overwhelming emotions. Dissociation is not exclusive to individuals diagnosed with dissociative disorders - it can occur in anyone facing highly emotionally overwhelming situations. Trauma, especially childhood trauma like abuse or neglect, is a primary cause of dissociation. Other factors such as adverse childhood experiences, attachment disruptions, biological factors, and cultural/societal factors can also contribute to dissociation. Dissociation serves as a way for individuals to cope with overwhelming emotions by mentally disconnecting or escaping from distressing situations. It often co-occurs with other mental health conditions such as PTSD, depression, anxiety, and substance abuse. Recognizing the common symptoms of dissociation, such as memory loss, distorted perception, and a sense of unreality, is crucial. Understanding these symptoms helps individuals evaluate whether they still rely on dissociation when it is no longer necessary. Sometimes, people may experience a distorted sense of reality or a feeling of unreality in their surroundings. However, it is important not to add fear to these experiences but rather approach them with curiosity. Keeping a journal and discussing these perceptions with a therapist or coach can provide insights and understanding. Feeling detached from oneself, emotions, or having a blurred sense of identity can also be signs of dissociation. These symptoms are often present when individuals are coming out of an anxious or panic state. Inability to cope with emotional or professional stress is another indicator of dissociation, as individuals feel disconnected and unable to handle such challenges. Learn more about your ad choices. Visit megaphone.fm/adchoices

In Season 2 Episode 7 of Heal Yourself with the Law of Attraction we will discuss Human Design in more depth, specifically the energy centers.We will discuss:Understanding the significance of having an undefined splenic center in a Human Design chartThe role of life experience and gaining wisdom through health challengesMy Personal Health JourneyDiscovering and managing a gluten allergy and its impact on healthAddressing chronic neck and back pain through holistic approachesExploring the connection between unresolved emotions and physical painNavigating hormone imbalances, rapid weight gain, and PCOS diagnosisSeeking the guidance of an integrative doctor for comprehensive health managementThe importance of comprehensive testing and personalized approaches to address inflammation and hormone balanceMindset and Gratitude in HealingEmbracing a healing mindset and focusing on gratitude during the health journeyUnderstanding the power of positive thoughts and beliefs on physical healthPersonal experiences with the transformative impact of mindset workChallenges and Lessons LearnedDealing with a severe reaction to black mold exposure and the discovery of a dust mite allergyExploring the lessons and wisdom gained from health challengesSharing insights and experiences to support others facing similar strugglesConnection Between Human Design and HealthLinking the health journey to the concept of Human Design and its impact on personal well-beingUnderstanding the connection between an undefined splenic center and health challengesExploring the transformative potential of health challenges in gaining wisdom and supporting othersHolistic Approach to Well-beingEmphasizing the importance of listening to the body and being an advocate for healthRecognizing the holistic nature of well-being, encompassing physical, emotional, and spiritual aspectsHighlighting the need for a comprehensive approach to health that addresses all aspects of the self Important InformationGet Your Human Design Charthttps://www.myhumandesign.com/get-your-chart/Podcast website and FREE resourceswww.healyourselfwithloa.comPrivate 1:1 coachingwww.healyourselfwithloa.com/coachingFollow me on socialInstagram: https://www.instagram.com/healyourselfwithloa/Tik Tok: https://www.tiktok.com/@healyourselfwithloaPinterest: https://www.pinterest.com/tecladifrancesco/

During this episode Heathar Shepard, classical homeopath and author of The Sunlight Rx and The Sunlight Diet, talks about root causes of germophobia. If you think this mindset is something that happens by chance or if you struggle with it and you're at your wits end as to why it's such a struggle for you, hang tight, Heathar explains why germophobia and anxiety of infectious disease actually develop in an organism. Heathar also takes you on a deep dive into genetic predisposition and why the alternative world of supplements and genetic testing is total horse s^&t.

In this episode Dr. Labbe discusses:Introduction:Autoimmune diseases often have invisible symptoms and can fluctuate over time.Common autoimmune diseases include Lupus, arthritis, multiple sclerosis, psoriasis, fibromyalgia, and Hashimoto's thyroiditis.Understanding Autoimmunity:Autoimmunity occurs when the immune system mistakenly attacks the body's own tissues.The immune system misbehaves, attacking healthy tissues instead of external threats.Hashimoto's thyroiditis is an example of an autoimmune disease.Causes of Autoimmunity:Autoimmune diseases can be caused by a combination of genetic predisposition, environmental factors, and epigenetics.Predisposition refers to certain characteristics that make individuals more susceptible to developing an autoimmune disease.Genetic factors like HLA, p53, and IL10 genes have been associated with Hashimoto's and other autoimmune diseases.Environmental triggers, such as intestinal permeability (leaky gut), infections like Epstein Barr virus, and chronic infections like Lyme disease, can contribute to autoimmunity.Exposure to pollutants, toxins, chemicals, heavy metals, and mold can also act as triggers.Physical or psychological trauma and chronic stress can impact the immune system and trigger autoimmune irregularities.Epigenetics, the study of biological processes that switch genes on and off, can play a role in the development of autoimmune diseases.The Importance of Identifying Triggers and Predispositions:Understanding triggers and predispositions is crucial in managing autoimmune diseases.Functional blood tests and specialized labs like Cyrex Labs can help identify infections, hormonal imbalances, allergies, immune cell counts, and food intolerances.Identifying triggers and predispositions can provide insights into the causes of autoimmune diseases and guide personalized treatment approaches.Recognizing and addressing triggers can help reduce symptoms and improve overall health.Conclusion:Autoimmune diseases require a comprehensive understanding of triggers, predispositions, and lifestyle factors.Identifying and addressing triggers is essential for effectively managing Hashimoto's and other autoimmune conditions.Functional testing and consultations with healthcare professionals can provide valuable insights and guidance in addressing autoimmune triggers and improving overall well-being.Resources:FEELING LOUSY IS NOT "JUST PART OF GETTING OLDER." IT'S ALL INCLUDED IN THIS PRESENTATION: 8 MASSIVE HYPOTHYROID MYTHS EVERY WOMAN SHOULD KNOW. Sign up for this free presentation to learn why your thyroid + hormones are making you feel like you're falling apart...and what you can do to start feeling better right now! https://vips.thyrosisters.com/webinar-optin-aWant to work with Dr. Labbe to unravel your thyroid mystery and get you back to feeling and functioning great again?Book A FREE Clarity Call: https://vips.thyrosisters.com/book-call-aFollow Us On Instagram: https://www.instagram.com/thyrosisters/

A new research paper was published in Aging (Aging-US) Volume 15, Issue 9, entitled, “Exogenous exposures shape genetic predisposition to lipids, Alzheimer's, and coronary heart disease in the MLXIPL gene locus.” In this new study, researchers Yury Loika, Elena Loiko, Fan Feng, Eric Stallard, Anatoliy I. Yashin, Konstantin Arbeev, Allison L. Kuipers, Mary F. Feitosa, Michael A. Province, and Alexander M. Kulminski from Duke University, University of Pittsburgh and Washington University School of Medicine examined associations of single nucleotide polymorphisms (SNPs) of the MLXIPL lipid gene with Alzheimer's (AD) and coronary heart disease (CHD) and potentially causal mediation effects of their risk factors, high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) in two samples of European ancestry from the United States (US) (22,712 individuals 587/2,608 AD/CHD cases) and the United Kingdom Biobank (UKB) (232,341 individuals; 809/15,269 AD/CHD cases). “Our results suggest that these associations can be regulated by several biological mechanisms and shaped by exogenous exposures.” Two patterns of associations (represented by rs17145750 and rs6967028) were identified. Minor alleles of rs17145750 and rs6967028 demonstrated primary (secondary) association with high TG (lower HDL-C) and high HDL-C (lower TG) levels, respectively. The primary association explained ~50% of the secondary one suggesting partly independent mechanisms of TG and HDL-C regulation. The magnitude of the association of rs17145750 with HDL-C was significantly higher in the US vs. UKB sample and likely related to differences in exogenous exposures in the two countries. rs17145750 demonstrated a significant detrimental indirect effect through TG on AD risk in the UKB only (βIE = 0.015, pIE = 1.9 × 10−3), which suggests protective effects of high TG levels against AD, likely shaped by exogenous exposures. Also, rs17145750 demonstrated significant protective indirect effects through TG and HDL-C in the associations with CHD in both samples. In contrast, rs6967028 demonstrated an adverse mediation effect through HDL-C on CHD risk in the US sample only (βIE = 0.019, pIE = 8.6 × 10−4). This trade-off suggests different roles of triglyceride mediated mechanisms in the pathogenesis of AD and CHD. “Finally, the results of this study suggest that genetic associations of SNPs from the MLXIPL gene locus with lipids, AD, and CHD are shaped by exogenous exposures. Further study of the related biological mechanisms can help to elucidate the related, modifiable risk factors.” DOI - https://doi.org/10.18632/aging.204665 Corresponding authors - Yury Loika - yury.loika@duke.edu, and Alexander M. Kulminski - alexander.kulminski@duke.edu Keywords - aging, MLXIPL, lipids, triglycerides, coronary heart disease, Alzheimer's disease About Aging-US Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at https://www.Aging-US.com​​ and connect with us: SoundCloud - https://soundcloud.com/Aging-Us Facebook - https://www.facebook.com/AgingUS/ Twitter - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM

In this episode, Chris Curry sits down with Drs. John Henson & Eric Ring. Together, Ring and Henson created the Pediatric Cancer Predisposition Clinic at the Children's Hospital of Georgia. The clinic focuses on children who have a predisposition to cancer, which is a genetic mutation that increases the chance of developing cancer at an earlier age.

In this bonus episode Associate Editor, Dr. Mario Cazzola discusses the review series on Germline predisposition to hematologic malignancies with authors, Dr. Lucy Godley, Dr. Anna Brown, and Dr. Dennis Hickstein.   

Bulletproof Hygiene Podcast Episode 101 Host: Brittany Simon, CRDH, BASDH Guest: Dr. Bart Santos (https://www.instagram.com/dj2drbsantos/?hl=en) Key Takeaways:Introduction Common TMJ Issues Being Treated On A Daily Basis Difference Between Disc Displacement or Muscular Predisposition To Developing The Condition References:Hygiene Mastermind - https://bulletproofmastermind.com Summit - https://bulletproofsummit.com/ Mighty Networks - Bulletproof Hygiene IDM Revolution! Symposium: Connecting the Dots of Oral & Systemic Health https://www.idmscholarsociety.com/revolution-symposium Tweetables: What we don't know we don't treat. -Dr. Bart Santos Don't put bandaids on things that need cast. -Dr. Bart Santos

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/oR0KN5VFDVc Tune in as our host, Dr. Brenda Weigel from the University of Minnesota, is joined by Dr. Garrett Brodeur to discuss his expertise in genetic predispositions in childhood cancer. Dr. Brodeur is the Director of the Pediatric Cancer Predisposition Program at the Children's Hospital of Philadelphia (CHOP) - and listen in as he discusses his journey leading up to cancer predisposition, what the program entails, as well as the process of screening & surveillance protocols. To learn more about this program, please visit https://www.chop.edu/centers-programs/hereditary-cancer-predisposition-program ----more---- Have any thoughts? Questions? Ideas for future topics? Email us at TWIPO@solvingkidscancer.org. Subscribe to TWIPO to get notifications of new uploads. Want to listen to TWIPO's past episodes? Visit www.solvingkidscancer.org/podcast

Working on Our Shaakilat (Predisposition) - Nouman Ali Khan - Animated

In this week's episode, research shows that in patients with myelodysplastic syndromes, or MDS, the frequency of pathogenic or likely pathogenic germline variants is relatively high across all age groups, not just younger patients. Based on these results, it may be time to expand genetic testing to all patients.  Next, we'll review primary results of a prospective, multicenter study of children with acute leukemias or MDS who underwent T-cell receptor αβ+ and CD19+ cell-depleted haploidentical HCT with reduced-toxicity conditioning. Finally, an emerging unmet need related to CAR T cell therapy: patients who progress after receiving CAR T cells have poor outcomes and no agreed upon standard of care. We'll review findings from a large registry study demonstrating infrequent responses to post-CAR T cell treatment and short survival times, highlighting a need for novel strategies. 

How you communicate to yourself is critical to how you communicate with other people. Learn how to discover your own value first before taking the lead with others. #ThePitch #INICIVOX

BUY ISLAMIC BOOKS by The Sincere Seeker for Adults & Children on AMAZON: https://www.amazon.com/thesincereseekerConvert to Islam and Become Muslim in a 5-min Call!  Schedule your call now! https://www.thesincereseeker.com/convert-to-islam-and-become-muslim/FOLLOW The Sincere Seeker on social media to stay up to date

BUY ISLAMIC BOOKS by The Sincere Seeker for Adults & Children on AMAZON: https://www.amazon.com/thesincereseekerConvert to Islam and Become Muslim in a 5-min Call!  Schedule your call now! https://www.thesincereseeker.com/convert-to-islam-and-become-muslim/FOLLOW The Sincere Seeker on social media to stay up to date

Huberman Lab Podcast Notes Key Takeaways Nicotinic receptors and cannabinoid receptors are not in the brain for smoking tobacco or marijuana; they are endogenous receptors that support specific functions (such as acetylcholine) when appropriateCannabis dependence: when smoked or ingested, THC and CBD bind to cannabinoid receptors and tap into endogenous receptors with much more potency – your endogenous receptors are outcompeted  Sativa strains increase mood, alertness, and focus of the prefrontal cortex while decreasing stress and threat detection in the amygdala – this combination allows people to enter narrowed focus  Indica strains reduce the activity of the prefrontal cortex and induce relaxation and sedative effects but also lead to profound defects in short-term memory because it reduces the activity of the hippocampusThere are no predictors of what your reaction will be to a given strain (e.g., whether you experience relaxation or paranoia)“Cannabis increases creativity but through changes in personality that tap into the creative process, rather than directly impacting the neural circuits that, for instance, ‘turn on' creativity.” – Dr. Andrew HubermanSmoking cannabis increases prolactin levels (especially in those who smoke more than twice per week); dopamine and prolactin are mutually inhibitory – this is important in sexual arousal which will be suppressed if prolactin is elevated with cannabis useFertility: THC (not CBD) is inhibitory for gonadotropin-releasing hormone which ultimately reduces testosterone in men, ovarian health in women“Cannabis use itself makes people 4x likelier to develop a chronic, major depression.” – Dr. Andrew HubermanChronic cannabis is not safe for the developing brain and body because of thinning of gray matter that occurs – risks include depression, anxiety, psychotic events, inability to balance moodThe more potent the THC concentration, the higher the likelihood of developing a major anxiety disorder or psychotic episode later in lifeRead the full notes @ podcastnotes.orgIn this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one's propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Cannabis (Marijuana) (00:04:46) New: Huberman Lab Premium (00:07:03) Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety (00:10:08) Levels, Thesis, InsideTracker (00:14:01) Momentous Supplements (00:15:08) Cannabis Strains, Psychoactive Compounds: THC & CBD (00:19:34) Sativa vs. Indica, Stimulant vs. Relaxation Effects (00:25:55) Hybrid Cannabis Strains, Type 1, 2 & 3 Strains (00:30:41) AG1 (Athletic Greens) (00:31:56) Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1) (00:40:35) THC, CBD vs. Endogenous Cannabinoids, Dependence (00:43:14) Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function (00:53:07) Biological Effects of Cannabis (00:56:29) Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia (01:04:58) Cannabis Indica & Subjective Effects, Memory, Dosage (01:09:41) Brain Areas Affected by THC & CBD, Side Effects (01:16:08) Creativity: Convergent vs. Divergent Thinking & Dopamine (01:26:41) Does Cannabis Increase Creativity? (01:35:08) Chronic Cannabis Use & Changes in Speech Patterns (01:46:46) Cannabis & Libido, Dopamine & Prolactin (01:56:55) Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility (02:06:53) Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences (02:10:06) Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development (02:18:13) Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance (02:25:57) Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis (02:34:36) Adolescent Cannabis Use: Brain Development & Mental Health Disorders (02:41:44) Cannabis & Pain Management, Divergent Effects of Cannabis (02:44:54) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn  Title Card Photo Credit: Mike Blabac Disclaimer

Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one's propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Cannabis (Marijuana) (00:04:46) New: Huberman Lab Premium (00:07:03) Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety (00:10:08) Levels, Thesis, InsideTracker (00:14:01) Momentous Supplements (00:15:08) Cannabis Strains, Psychoactive Compounds: THC & CBD (00:19:34) Sativa vs. Indica, Stimulant vs. Relaxation Effects (00:25:55) Hybrid Cannabis Strains, Type 1, 2 & 3 Strains (00:30:41) AG1 (Athletic Greens) (00:31:56) Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1) (00:40:35) THC, CBD vs. Endogenous Cannabinoids, Dependence (00:43:14) Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function (00:53:07) Biological Effects of Cannabis (00:56:29) Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia (01:04:58) Cannabis Indica & Subjective Effects, Memory, Dosage (01:09:41) Brain Areas Affected by THC & CBD, Side Effects (01:16:08) Creativity: Convergent vs. Divergent Thinking & Dopamine (01:26:41) Does Cannabis Increase Creativity? (01:35:08) Chronic Cannabis Use & Changes in Speech Patterns (01:46:46) Cannabis & Libido, Dopamine & Prolactin (01:56:55) Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility (02:06:53) Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences (02:10:06) Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development (02:18:13) Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance (02:25:57) Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis (02:34:36) Adolescent Cannabis Use: Brain Development & Mental Health Disorders (02:41:44) Cannabis & Pain Management, Divergent Effects of Cannabis (02:44:54) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn  Title Card Photo Credit: Mike Blabac Disclaimer

In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one's propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Cannabis (Marijuana) (00:04:46) New: Huberman Lab Premium (00:07:03) Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety (00:10:08) Levels, Thesis, InsideTracker (00:14:01) Momentous Supplements (00:15:08) Cannabis Strains, Psychoactive Compounds: THC & CBD (00:19:34) Sativa vs. Indica, Stimulant vs. Relaxation Effects (00:25:55) Hybrid Cannabis Strains, Type 1, 2 & 3 Strains (00:30:41) AG1 (Athletic Greens) (00:31:56) Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1) (00:40:35) THC, CBD vs. Endogenous Cannabinoids, Dependence (00:43:14) Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function (00:53:07) Biological Effects of Cannabis (00:56:29) Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia (01:04:58) Cannabis Indica & Subjective Effects, Memory, Dosage (01:09:41) Brain Areas Affected by THC & CBD, Side Effects (01:16:08) Creativity: Convergent vs. Divergent Thinking & Dopamine (01:26:41) Does Cannabis Increase Creativity? (01:35:08) Chronic Cannabis Use & Changes in Speech Patterns (01:46:46) Cannabis & Libido, Dopamine & Prolactin (01:56:55) Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility (02:06:53) Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences (02:10:06) Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development (02:18:13) Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance (02:25:57) Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis (02:34:36) Adolescent Cannabis Use: Brain Development & Mental Health Disorders (02:41:44) Cannabis & Pain Management, Divergent Effects of Cannabis (02:44:54) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn  Title Card Photo Credit: Mike Blabac Disclaimer

Hello all! We are back with our monthly Q&A. To kick it off, we have a short conversation on maternal instincts.  Next, we discuss how one woman should handle her mother-in-law's request to be called "Mama".  Then we review the very few reasons when an induction is absolutely needed, how long you can go with ruptured membranes before inducing labor, followed by a question on familial history and  a genetic predisposition to needing a cesarean birth.  Another mother calls in to express her postpartum exhaustion and relationship struggles, as she feels depleted by the day and with nothing left to give her husband at the end of it.  One mother wonders if being sick during pregnancy is harmful to her baby, and finally we discuss Lotus birth--what is it and is it un-hygienic?In our extended version, available via Apple Subscriptions, we'll be responding to one woman's concern about pre-empting family issues postpartum in her quest to get them to provide help when they visit. Another mom asked our opinion on amber teething necklaces, and Trisha explains how they're often misunderstood as actual "teething" products, when they're not. There were some breastfeeding questions related to frequent plugged ducts; fever and low milk supply. And finally, one birth worker is asking whether amnio-infusion is a reasonable solution when amniotic waters are low. If you don't listen on an Apple device and would like access to our exclusive and extended episodes, email us at Contact@DownToBirthShow.com and put "Extended Episodes" in the subject line.Thank you as always for your great questions and see you next week! If you would like to submit a question, please call and leave us a message with your question at (802) 438-3696 That's 802-GET-DOWN.**********This show is sponsored by:Silverette USA*DYPER*Beautiful Births and Beyond*Postpartum Soothe*Baby Notebook - Get the App Here*Use promo code DOWNTOBIRTHConnect with Cynthia and Trisha at:Instagram: @downtobirthshow on InstagramEmail: Contact@DownToBirthShow.comCall: (802) 438-3696 (802-GET-DOWN)Work with Cynthia:Email: Cynthia@HypnoBirthingCT.com Text: 203-952-7299 to RSVP to attend a free information session live on Zoom. Upcoming dates are posted at HypnoBirthingCT.com. You can also sign up for our Fourth Trimester Workshop,  Breastfeeding Workshop or Cynthia's HypnoBirthing classes and weekly postpartum support groups at HypnoBirthing of Connecticut. Work with Trisha at:Email: Trisha.Ludwig@gmail.com for online breastfeeding consulting services or text 734-649-6294 for more info.We serve women and couples coast to coast with our live, online monthly HypnoBirthing classes, support groups and prenatal/postpartum workshops. We are so grateful for your reviews and shares!Please remember we don't provide medical advice, and to speak with your licensed medical provider related to all your healthcare matters. Thanks so much for joining in the conversation, and see you next week!

Episode 396  - The Brain and Alcohol – Genetic Predisposition   Today we have Rene.   He is 33, from California, and took his last drink January 18, 2022.   Register for RE's AF Photo Class:  https://www.recoveryelevator.com/afphoto/   SoberLink:  https://www.soberlink.com/recovery-elevator   Highlights from Paul   Alcohol has many biochemical and neurochemical effects on the brain. There are dramatic changes in the neurons that control the release of serotonin when we consume alcohol. Serotonin is the feel-good chemical and 80% of it is created in the gut. When we mix alcohol and serotonin it gets converted into acetaldehyde. This acetaldehyde acts as a toxin.   Alcohol changes the relationship between the hypothalamus, the pituitary gland, and the adrenals.  The adrenals release chemicals called epinephrine and cortisol, which are involved in the longer-term stress response.   People who consistently drink are more stressed out at baseline. They have more cortisol released form their adrenal glands even when they are not drinking. Consequently, they feel more stressed and more anxiety when they are not drinking. Many scientists agree that stress is the number one contributor to disease.   When we overload the brain with alcohol, it's almost too much to process and the activity of neurons in the hippocampus, which is involved with memory formation, are strained and then they completely shut off – that is a blackout.  You can still be functioning, some high functioning, but the memory forming part of your brain, the hippocampus, clocks out.   Many believe that alcoholism is hereditary.  Recent studies, including one of twins conducted by Dr. Gabor Mate indicate genetics may not be as much of a contributor as we once thought.  Epigenetics indicate that environment influences gene expression and gene mutations.  Science is beginning to accept that environmental factors cause or influence addictions.  The ten-fold increase in alcoholism supports that theory.     Dr. Andrew Huberman's podcast provides much more detail on the science behind many of these theories.  Take a listen if you would like to learn more:  https://open.spotify.com/episode/2ebY3WNejLNbK47emgjd1E?si=bf71f9f038bc4826   Better Help:  www.betterhelp.com/elevator - 10% off your first month. #sponsored                                                                               [14:37]  Rene has been sober for over six months. He is 34 and a single Dad He is an entrepreneur and enjoys going to the gym, exploring the outdoors, hiking and the beach.   Rene is first generation American, and his family is very supportive.  He grew up around drinking, it was normalized.    He got drunk once during his senior year of high school.  He didn't drink again until after he broke up with his first girlfriend years later. Drinking became a reward, then it became a daily habit.  Working in the restaurant industry, drinking was expected.  He was fired once for drinking.    It didn't occur to Rene that drinking was a problem.  He began counseling and the counselor recommended AA.  Rene found it easy to see the similarities; he felt like he found his people.  He was planning to join the military when he learned he was about to become a father.  Eventually, he won sole custody of his daughter which dashed his hopes of joining the military.  The combination of issues sent him back to drinking.  He controlled his drinking for over a year, and it worked until it didn't.   Rene went back to AA and got a sponsor and a fitness coach.  Consistency helps him maintain his sobriety.  He is feeling mentally and physically strong.     [57:35] Kris's Summary   Seasonal shifts can put you on edge.  Share your experience: kris@recoveryelevator.com.   Upcoming events, retreats, and courses: You can find more information about our events   Resources Connect with Cafe RE - Use the promo code OPPORTUNITY to waive the set-up fee. Recovery Elevator YouTube - Subscribe here! Sobriety Tracker iTunes    Recovery Elevator- We took the elevator down.  We need to take the stairs back up. I love you guys.

Huberman Lab Podcast Notes Key Takeaways Chronic alcohol intake, even at low to moderate levels (1-2 drinks per day or 7-14 per week), can disrupt the brainWhen people drink, the prefrontal cortex and top-down inhibition are diminished and impulsive behavior increases – this is true in the short term while drinking, and rewires circuitry outside of drinking events in chronic drinkers (even those who drink 1-2 nights per week, long term)Damaging effects to the prefrontal cortex and rewiring of neural circuitry are reversible with 2-6 months of abstinence for most social/casual drinkers; chronic users will partially recover but likely feel long-lasting effectsWhen people drink there is a shutdown of the prefrontal cortex and circuits that control memory, then there's a fork in the road: group 1 – people who feel sedated after a few drinks; group 2 – people who do not feel sedated after a few drinks (predisposition to alcoholism)People who start drinking at a younger age (13-15) are more likely to develop dependence, regardless of the history of alcoholism in their family; people who delay drinking to early 20s are less likely to develop dependence even if there's a family historyPeople who drink consistently (even in small amounts i.e., 1 per night) experience increases in cortisol release from adrenal glands when not drinking so feel more stress and more anxiety when not drinkingWith increased alcohol tolerance, you get less and less of the feel good blip and more and more of the pain signaling (so behaviorally you drink more to try to activate those dopamine and serotonin molecules again)The risk of breast cancer increases among women who drink – for every 10 grams of alcohol consumed per day, there's a 4-13% increase in the risk of cancer (alcohol increases tumor growth & suppresses molecules that inhibit tumor growth)Regular consumption of alcohol increases estrogen levels of males and females through aromatizationRead the full notes @ podcastnotes.orgIn this episode, I discuss the physiological effects that drinking alcohol has on the brain and body at different levels of consumption and over time. I also describe genetic differences that predispose certain individuals to alcoholism, binge and habit-drinking. I explain alcohol metabolism in simple terms and how it effectively acts as a poison, leading to cellular stress and damage. I then explain that it impacts neuronal function and changes our thinking and behavior – hallmarks of inebriation. I also discuss how alcohol consumption of different amounts impacts inflammation, stress, neurodegeneration, and cancer risk and negatively impacts the gut microbiome, brain thickness, hormone balance, mood and feelings of motivation. Additionally, I discuss the biology of hangovers and describe science-based strategies to mitigate the severity of a hangover. Since alcohol is one of the most widely consumed recreational substances, this episode ought to be of relevance to everyone.  Indeed, even low-to-moderate alcohol consumption negatively impacts the brain and body in direct ways. The goal of this episode is to help people make informed decisions about their alcohol consumption that are in keeping with their mental and physical health goals.  Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Effects of Alcohol Consumption (00:02:25) Momentous Supplements  (00:03:19) Low to Moderate Alcohol Consumption & Neurodegeneration  (00:06:52) Levels, Eight Sleep, ROKA  (00:10:46) Historical Context & Uses of Alcohol  (00:13:28) Alcohol Metabolism, “Empty Calories”  (00:18:23) Inebriation: Top-Down Inhibition, Impulsivity & Memory Formation (00:24:23) Long-Lasting Effects & Impulsivity, Neuroplasticity & Reversibility  (00:27:55) Food & Alcohol Absorption (00:30:07) Alcohol & Serotonin, SSRIs & Depression, Risk for Alcoholism, Blackouts (00:37:39) Predisposition for Alcoholism; Chronic Consumption, Cortisol & Stress (00:44:53) AG1 (Athletic Greens) (00:46:07) Genetic Predisposition for Alcoholism, Consuming Alcohol Too Young (00:52:27) Gut-Liver-Brain Axis: Alcohol, Gut Microbiome, Inflammation & Leaky Gut  (00:59:46) Tool: Improving/Replenishing Gut Microbiome  (01:02:44) Reducing Alcohol Consumption & Stress  (01:04:25) Hangover: Alcohol & Sleep, Anxiety, Headache (01:12:11) Hangover Recovery, Adrenaline & Deliberate Cold Exposure  (01:17:16) Hangover Recovery, Dehydration & Electrolytes (01:20:45) Types of Alcohol & Hangover Severity, Congeners   (01:25:25) Alcohol Tolerance, Dopamine & Serotonin, Pleasure-Pain Balance    (01:33:36) Are There Any Positive Effects of Alcohol?, Resveratrol  (01:35:42) Alcohol & Brain Thickness  (01:37:11) Alcohol & Cancer Risk: DNA Methylation, Breast Cancer Risk  (01:44:31) Mitigating Cancer Risk, Folate, B Vitamins  (01:46:54) Alcohol & Pregnancy, Fetal Alcohol Syndrome  (01:50:58) Hormones: Testosterone & Estrogen Balance (01:55:09) Negative Effects of Alcohol Consumption  (01:58:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer

Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, I discuss the physiological effects that drinking alcohol has on the brain and body at different levels of consumption and over time. I also describe genetic differences that predispose certain individuals to alcoholism, binge and habit-drinking. I explain alcohol metabolism in simple terms and how it effectively acts as a poison, leading to cellular stress and damage. I then explain that it impacts neuronal function and changes our thinking and behavior – hallmarks of inebriation. I also discuss how alcohol consumption of different amounts impacts inflammation, stress, neurodegeneration, and cancer risk and negatively impacts the gut microbiome, brain thickness, hormone balance, mood and feelings of motivation. Additionally, I discuss the biology of hangovers and describe science-based strategies to mitigate the severity of a hangover. Since alcohol is one of the most widely consumed recreational substances, this episode ought to be of relevance to everyone.  Indeed, even low-to-moderate alcohol consumption negatively impacts the brain and body in direct ways. The goal of this episode is to help people make informed decisions about their alcohol consumption that are in keeping with their mental and physical health goals.  Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Effects of Alcohol Consumption (00:02:25) Momentous Supplements  (00:03:19) Low to Moderate Alcohol Consumption & Neurodegeneration  (00:06:52) Levels, Eight Sleep, ROKA  (00:10:46) Historical Context & Uses of Alcohol  (00:13:28) Alcohol Metabolism, “Empty Calories”  (00:18:23) Inebriation: Top-Down Inhibition, Impulsivity & Memory Formation (00:24:23) Long-Lasting Effects & Impulsivity, Neuroplasticity & Reversibility  (00:27:55) Food & Alcohol Absorption (00:30:07) Alcohol & Serotonin, SSRIs & Depression, Risk for Alcoholism, Blackouts (00:37:39) Predisposition for Alcoholism; Chronic Consumption, Cortisol & Stress (00:44:53) AG1 (Athletic Greens) (00:46:07) Genetic Predisposition for Alcoholism, Consuming Alcohol Too Young (00:52:27) Gut-Liver-Brain Axis: Alcohol, Gut Microbiome, Inflammation & Leaky Gut  (00:59:46) Tool: Improving/Replenishing Gut Microbiome  (01:02:44) Reducing Alcohol Consumption & Stress  (01:04:25) Hangover: Alcohol & Sleep, Anxiety, Headache (01:12:11) Hangover Recovery, Adrenaline & Deliberate Cold Exposure  (01:17:16) Hangover Recovery, Dehydration & Electrolytes (01:20:45) Types of Alcohol & Hangover Severity, Congeners   (01:25:25) Alcohol Tolerance, Dopamine & Serotonin, Pleasure-Pain Balance    (01:33:36) Are There Any Positive Effects of Alcohol?, Resveratrol  (01:35:42) Alcohol & Brain Thickness  (01:37:11) Alcohol & Cancer Risk: DNA Methylation, Breast Cancer Risk  (01:44:31) Mitigating Cancer Risk, Folate, B Vitamins  (01:46:54) Alcohol & Pregnancy, Fetal Alcohol Syndrome  (01:50:58) Hormones: Testosterone & Estrogen Balance (01:55:09) Negative Effects of Alcohol Consumption  (01:58:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer

In this episode, I discuss the physiological effects that drinking alcohol has on the brain and body at different levels of consumption and over time. I also describe genetic differences that predispose certain individuals to alcoholism, binge and habit-drinking. I explain alcohol metabolism in simple terms and how it effectively acts as a poison, leading to cellular stress and damage. I then explain that it impacts neuronal function and changes our thinking and behavior – hallmarks of inebriation. I also discuss how alcohol consumption of different amounts impacts inflammation, stress, neurodegeneration, and cancer risk and negatively impacts the gut microbiome, brain thickness, hormone balance, mood and feelings of motivation. Additionally, I discuss the biology of hangovers and describe science-based strategies to mitigate the severity of a hangover. Since alcohol is one of the most widely consumed recreational substances, this episode ought to be of relevance to everyone.  Indeed, even low-to-moderate alcohol consumption negatively impacts the brain and body in direct ways. The goal of this episode is to help people make informed decisions about their alcohol consumption that are in keeping with their mental and physical health goals.  Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Effects of Alcohol Consumption (00:02:25) Momentous Supplements  (00:03:19) Low to Moderate Alcohol Consumption & Neurodegeneration  (00:06:52) Levels, Eight Sleep, ROKA  (00:10:46) Historical Context & Uses of Alcohol  (00:13:28) Alcohol Metabolism, “Empty Calories”  (00:18:23) Inebriation: Top-Down Inhibition, Impulsivity & Memory Formation (00:24:23) Long-Lasting Effects & Impulsivity, Neuroplasticity & Reversibility  (00:27:55) Food & Alcohol Absorption (00:30:07) Alcohol & Serotonin, SSRIs & Depression, Risk for Alcoholism, Blackouts (00:37:39) Predisposition for Alcoholism; Chronic Consumption, Cortisol & Stress (00:44:53) AG1 (Athletic Greens) (00:46:07) Genetic Predisposition for Alcoholism, Consuming Alcohol Too Young (00:52:27) Gut-Liver-Brain Axis: Alcohol, Gut Microbiome, Inflammation & Leaky Gut  (00:59:46) Tool: Improving/Replenishing Gut Microbiome  (01:02:44) Reducing Alcohol Consumption & Stress  (01:04:25) Hangover: Alcohol & Sleep, Anxiety, Headache (01:12:11) Hangover Recovery, Adrenaline & Deliberate Cold Exposure  (01:17:16) Hangover Recovery, Dehydration & Electrolytes (01:20:45) Types of Alcohol & Hangover Severity, Congeners   (01:25:25) Alcohol Tolerance, Dopamine & Serotonin, Pleasure-Pain Balance    (01:33:36) Are There Any Positive Effects of Alcohol?, Resveratrol  (01:35:42) Alcohol & Brain Thickness  (01:37:11) Alcohol & Cancer Risk: DNA Methylation, Breast Cancer Risk  (01:44:31) Mitigating Cancer Risk, Folate, B Vitamins  (01:46:54) Alcohol & Pregnancy, Fetal Alcohol Syndrome  (01:50:58) Hormones: Testosterone & Estrogen Balance (01:55:09) Negative Effects of Alcohol Consumption  (01:58:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer

The AFFIRMATION ATTACK is a daily affirmation of the struggles we go-getters face, and these episodes remind you that: We struggle, too; and You can do this! If you liked this episode, let us know! || Share it on your socials and tag @paulttran || Forward it to a friend who could use these words || Consider supporting our work by minting a Crypto Badger Clan NFT (and get a bunch of incentives, too): www.cryptobadgerclan.com

  This episode of the It's A Mimic! podcast returns to the pages of Xanathar's Guide to Everything to cover the last subclass listed there, before looking at the pages of Tasha's Cauldron of Everything to see what new Monastic Traditions there are for Dungeons and Dragons 5th Edition.  It's not all punch punch kick kick, though, as the panel of Dungeon Masters has discovered.  So grab your brass knuckles and put on your gi, as this episode launches into three more subclasses, as well as the Optional Class Features offered in Tasha's.   Cold Open 0:00 Intro  1:02 Monk Overview 6:56 Commercial Break 21:22 Way of Astral Self 23:17 Way of Mercy 40:53 Social Media Info 57:01 Way of the Sun Soul 58:10 Character Builds 1:15:25 Outro 1:22:40 Post-Credit 1:23:46 Bloopers 1:27:22 DON'T FORGET TO LIKE & SUBSCRIBE! Available On: https://www.itsamimic.com iTunes at https://itunes.apple.com/ca/podcast/its-a-mimic/id1450770037 Spotify at https://open.spotify.com/show/3Y19VxSxLKyfg0gY0yUeU1 Podbean at https://itsamimic.podbean.com/  YouTube at https://www.youtube.com/channel/UCzQmvEufzxPHWrFSZbB8uuw Social: Facebook at https://www.facebook.com/itsamimic/ Instagram at https://www.instagram.com/itsamimic/?hl=en Reddit at https://www.reddit.com/r/ItsaMimic/ Email at info@itsamimic.com Dungeon Master:  Terry Williams Host 2:  Dan O'Coin Host 3:  Megan Lengle Written by:  Terry Williams and Adam Nason Director:  Terry Williams and Adam Nason Audio Editor:  Brad McMann Video Editor:  Adam Nason Produced by:  Brad McMann and Adam Nason Executive Producers:  Dan O'Coin and Adam Nason Intro/Outro Music by:  Cory Wiebe Logo by:  Katie Skidmore at https://www.instagram.com/clementineartportraits/ Current Gear: Microphone (USA) - https://amzn.to/2WWuCsz  Microphone (CAN) - https://amzn.to/2WTZ69G This post or video may contain affiliate links, which means we may receive a commission for purchases made through our links. This episode is meant to be used as an inspirational supplement for Dungeons & Dragons 5th Edition and tabletop roleplaying games in general.  It's A Mimic! does not own the rights to any Wizards of the Coasts products. Artwork included in this episode's visualizations is published and/or owned by Wizards of the Coast.

The next challenge for ecommerce sellers? A wave of returns. Plus: Will you soon be able to use "genetic predisposition" as ad targeting criteria? Wordpress takes a big leap forward. One of the world's biggest advertisers finds that spending more does indeed make them more. A bug at Google could be causing your search position to drop...Go Premium! No ads, more stories, and extended deep-dive weekend episodes — https://todayindigital.com/premiumADVERTISING as low as $20: https://todayindigital.com/ads JOIN OUR SLACK! https://todayindigital.com/slackFOLLOW US: https://todayindigital.com/socialmedia (TikTok, LinkedIn, Twitter, Facebook, and Reddit) ENJOYING THE SHOW?- Please tweet about us! https://b.link/pod-tweet- Rate and review us: https://todayindigital.com/rateus- Leave a voicemail: https://b.link/pod-voicemail FOLLOW TOD:- TikTok: https://b.link/pod-tiktok- Twitter: https://b.link/pod-twitter- LinkedIn: https://b.link/pod-linkedin Today in Digital Marketing is hosted by Tod Maffin (https://b.link/pod-todsite) and produced by engageQ digital (https://b.link/pod-engageq). Subscribe at https://TodayInDigital.com or wherever you get your podcasts. (Theme music by Mark Blevis. All other music licensed by Source Audio.)Does your brand need a podcast? Let us help: https://engageQ.com/podcastsPrivacy & Opt-Out: https://redcircle.com/privacy

Wanderer types and their Predisposition to Relationships

Temperament impacts preschool behaviors such as play groups, physical activities, independence, and following directions. Parents can learn their child's temperament and create environments that play to their child's natural tendencies instead of struggling with them.Send us an email: parenting@iastate.edu.Find us on Facebook or Twitter: @scienceofparent.This institution is an equal opportunity provider. For the full non-discrimination statement or accommodation inquiries, go to www.extension.iastate.edu/diversity/ext. 

Dr. Abigail Matthews, a clinical psychologist and associate director of the Eating Disorders program at Cincinnati Children's, joins us to discuss her newest research on eating disorders and the effects the pandemic has had. We learn more about her study, discuss types of eating disorders, biological predisposition to disordered eating and the stressors that can cause a perfect storm for illness to develop. This is a must-listen episode, particularly for parents of tweens and teens.   Resources:   To learn more about the Eating Disorder Program, please visit: https://www.cincinnatichildrens.org/health/e/eating-disorders   The National Eating Disorders Association https://www.nationaleatingdisorders.org/  

What is genetic predisposition? That is a great question. If you've noticed different types of conditions seem to run in your family, then you might have found yourself wondering if you're at risk. You may have even been wondering what a genetic predisposition is. If that sounds familiar, then you're in the right place. I'm here to answer that question in today's video. Watch and Enjoy! Dr. Kelly Shockley Key Moments in this Episode  ======================== 00:00 - Intro & Summary 00:57 - What is Genetic Predisposition? 03:47 - Can I Prevent a Genetic Predisposition From Occurring 09:24 - The Only Way to Know if You Are at Risk and What to do to Protect Yourself 12:47 - Check This Out! ACCESS MY TOTAL BODY MASTERY RESOURCES ========================================= 7-DAY EAT YOUR WAY TO BETTER BRAIN HEALTH MEAL PLAN A 7 day meal plan designed for busy people who don't have time to cook regularly, complete grocery list and tasty recipes that will have you getting healthier with each bite. https://ayrh.link/brain FROM SLUGGISH TO UNSTOPPABLE The exact roadmap that my patients use to achieve limitless energy, ninja-like focus and peak performance. https://chlabs.link/fstu-ebook THE QUICK-START GUIDE TO COMBATTING BURNOUT Proven strategy for never ending up with burnout again. https://chlabs.link/burnout 5-DAY TOTAL BODY MASTERY HEALTH CHALLENGE Warning: completion of this challenge may result in limitless energy, ninja-like focus, peak performance and total body mastery for the rest of your life. Learn exactly what is causing your health challenges and the proven system I use with all of my patients to help them easily take back full control of their health. https://chlabs.link/workshop 

EPISODE 24: The effect your diet has on your DNA and how you can test your genetics to determine what foods you should be eating. Eating the wrong foods for your DNA can cause anxiety, depression, inflammation and a whole list of other issues. This week the boys talk hacking your DNA through nutrition with Dr. Piper Gibson (aka @regeneratinghealth). A Children's Holistic Health and Nutritional Genomic Practitioner, Dr. Gibson brings us into the field of Natural Medicine and explains the value of genetic testing. Throughout the convo the group discusses: Nutritional Genomic testing and what it involves Predisposition to disorders & health issues Stress mitigation for both children and adults Dr. Gibson's approach to treatment and supplementation Josh and the good Dr. Gibson have conflicting opinions in one area, listen all the way through to find out what it is! Episode 24 is here and it's an informative one. See ya'll inside. Guest bio: Dr. Piper Gibson is a Board Certified Doctor of Natural Medicine and is also a Functional Diagnostic Nutrition Practitioner®, where she specializes in children's neurodevelopmental disorders such as ADHD, Tics/Tourette's, Anxiety, SPD, and ASD. She uses a natural, integrative approach to help her clients finally focus, function, and flourish. She is also the Corporate Clinical Educator for GX Sciences. Other topics covered include: How Dr. Gibson got into the field of Natural Medicine and she focuses on neurodevelopmental disorders Predisposition to disorders and health issues and how life events can trigger them Nutrition in schools: looking into what goes into our kids' bodies and the correlation to neurodevelopmental disorders Poor nutrition's long-term effects and approaches Dr. Gibson takes for treatment and supplementation Consistency required to improve anxiety or ADHD Process for reintroducing foods after eliminating them from a client's diet Food sensitivity testing vs GI mapping The implications of stress Where to find us: Show Hosts @joshlevinefitness - CONTACT FOR COACHING! (https://www.instagram.com/joshlevinefitness/) @travishawkesmedia - CONTACT FOR MEDIA! (https://www.instagram.com/travishawkesmedia/) Today's Guest @regeneratinghealth - FOLLOW FOR INFORMATION ON NUTRIGENOMICS & HOLISTIC HEALTH! (https://www.instagram.com/regeneratinghealth/) Podcast Producer @james_lohan - CONTACT FOR PODCAST PRODUCTION! (https://www.instagram.com/james_lohan/) Help us grow the show - Sub, Rate, and Review on Apple Podcasts! (https://podcasts.apple.com/us/podcast/struggle-to-strength-podcast/) Watch The Video Pod On Youtube! - Youtube Channel (https://www.youtube.com/channel/UCDgIa3ZBMm3KaNi_hoFXxhQ)