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This episode is brought to you by Cozy Earth and Pique Life. We know the seeds of Alzheimer's are planted at least twenty years before a diagnosis. So, it's never too early to make crucial lifestyle changes that can influence brain health and the risk of developing neurodegenerative diseases. Today on The Dhru Purohit Show, we're bringing you a special compilation episode featuring Dhru's conversations with leading experts on Alzheimer's and brain health. Dr. David Perlmutter explores the key factors that influence Alzheimer's risk and shares his top lifestyle strategies for prevention. He also discusses tools to assess brain energy usage and dives into the gut-brain connection. Dr. Mosconi explains what happens to a woman's brain during menopause and its connection to Alzheimer's disease. She also shares how recent research validates women's experiences in perimenopause and menopause, along with key lifestyle habits to prevent dementia and support a smoother transition. Dr. Perlmutter is a board-certified neurologist and five-time New York Times bestselling author. He is a fellow of the American College of Nutrition and serves on their Board of Directors. He has published extensively in peer-reviewed scientific journals, including the Journal of Alzheimer's Disease, Archives of Neurology, and Neurosurgery. Lisa Mosconi, PhD, is an associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine and the director of the Women's Brain Initiative and the Alzheimer's Prevention Clinic at Weill Cornell Medicine/NewYork-Presbyterian Hospital. She is the New York Times bestselling author of The XX Brain and Brain Food. In this episode, Dhru and his guests dive into: Genetics vs. Lifestyle: Their roles in diagnosis and impact on health (1:39) How Insulin Resistance Affects the Brain: Compromised brain energetics (04:20) Key ingredients that impact the body like sugar (11:11) Blood Sugar Game-Changers: Strategies for better management (20:14) Foods Dr. Perlmutter avoids & the gut-brain connection (27:32) The brain's energy demands & top antioxidant-rich foods (34:32) What's happening in the brain during menopause (38:31) Validating menopause symptoms and women's experiences (47:32) Brain changes in perimenopause & key transitions (52:02) Why the brain is unique and why consistency is key (59:32) Also mentioned: Full episode with David Perlmutter Full episode with Dr. Lisa Mosconi This episode is brought to you by Cozy Earth and Pique Life. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP. Right now, Pique Life is offering 20% off the Pu'er fermented black and green teas. Plus, you'll get a free beaker and frother when you go to piquelife.com/dhru. Learn more about your ad choices. Visit megaphone.fm/adchoices
I am delighted and honored today to interview Dr. Lisa Mosconi. She is an Associate Professor of Neuroscience in neurology and radiology at Cornell Medicine and Director of the Women's BRAIN Initiative and the Alzheimer's Prevention Clinic at Weill Cornell Medicine, New York Presbyterian Hospital. She is also a globally acclaimed neuroscientist with a Ph.D. in neuroscience and nuclear medicine and the author of the New York Times bestseller The XX Brain and, more recently, The Menopause Brain. In our conversation, we discuss how women's brains change during perimenopause and menopause, looking at the significance of puberty, pregnancy, and perimenopause, as well as the lack of medical research on women and medical gaslighting. We explore the concept of bikini medicine and its misconceptions regarding women's health and hormones alongside the crucial roles of hormones like estradiol, progesterone, and testosterone in our neuroendocrine system. Dr. Mosconi also provides insights into evolving menopausal treatments, including lifestyle interventions. Dr. Mosconi is an esteemed figure in neuroscience and a prominent voice in women's health. I am confident you will gain valuable insights and perspectives from my discussion with her today. IN THIS EPISODE YOU WILL LEARN: How women's brains change during perimenopause and menopause How the lack of information for young girls can lead to medical gaslighting and confusion during perimenopause Dr. Mosconi explains how a simple sugar is used as a tracer to track glucose metabolism in the brain during perimenopause Why brain changes during menopause may lead to mental fatigue and brain fog How the lack of training and research on menopause in medical residency programs leads to a poor understanding among clinicians Why women need to consider their brain and metabolic health during perimenopause Why estrogen is essential after menopause The benefits of HRT for menopausal women How stress impacts hormone production Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Lisa Mosconi On her website On Instagram
Join the Sanders sisters and expert Anne O Rice, RDH, as they discuss this debilitating and life-changing disease, and how to approach these patients and their needs with care. About Anne Anne has been a clinical dental hygienist for 35 years, is a speaker, writer, and consultant. She created Oral Systemic Seminars in 2017 and now devotes much of her time, focus and study to dementia prevention. Anne received her preceptor for the Bale/Doneen method, is a Certified Dementia Practitioner and in 2020 became certified as a Longevity Specialist with the Alzheimer's Research and Prevention Foundation, where she has also developed curriculum. She is a Fellow with The American Academy of Oral Systemic Health and on their advisory board. In 2024 she was added to Cloud Dentistry's Empowering Women in Dentistry board and has a column for RDH magazine focusing on oral systemic health and is also on their 2024 editorial advisory board. She was chosen in 2024 as a recipient of Sunstar's Award of Distinction and is looking forward to finishing her certification in the Buteyko Beathing Method. In 2021 Anne published her manuscript Alzheimer's Disease and Oral-Systemic Health Bidirectional Care Integration Improving Outcomes for Frontiers. She was included in an International Consortium of a diverse network of brain researchers, clinicians and institutions who support Alzheimer's prevention. Her consulting has brought her to Weill Cornell Medical Center's Alzheimer's Prevention Clinic, Florida Atlantic College Center for Brain Health, and the Atria Institute. Fine Anne Here: anneorice.com Facebook LinkedIn Instagram
Alzheimer's disease (AD) begins developing in the brain 20-30 years before symptoms start to present in patients. Recent evidence suggests that up to 40% of AD cases could potentially be prevented by addressing modifiable risk factors such as insufficient education, hearing loss, hypertension, obesity, smoking, depression, social isolation, physical inactivity, diabetes, excessive alcohol consumption, air pollution, and traumatic brain injury. Dr. Christina Shenvi is joined once again by Dr. Richard Isaacson, M.D., a Harvard-trained preventive neurologist and world-renowned researcher at the Institute for Neurodegenerative Diseases in Florida. In 2013, he founded the Alzheimer's Prevention Clinic at Weill Cornell Medicine and New York-Presbyterian, the first of its kind in the United States. In this episode of GEMCast they focus on the importance of individualized intervention and prevention as the future of AD treatment.
This episode is brought to you by Cozy Earth, One Skin, and Manukora. For years, women experiencing perimenopause and menopause have suffered through symptoms that were often dismissed as non-existent, not as severe as described, or just a normal part of aging. Fortunately, several practitioners are on a mission to change this narrative and help women reclaim optimal health and vitality. Today on the Dhru Purohit Show, we have a special compilation episode featuring Dhru's conversations with several podcast guests about hormone replacement therapy and the changes women undergo during perimenopause and menopause. Dr. Sara Gottfried explains why women experience shifts and how managing insulin resistance and muscle composition can unlock better health in mid-life. Dr. Mary Claire Haver shares insights on hormone replacement therapy and how to determine if it's right for you. Dr. Lisa Mosconi discusses powerful research on hormone replacement therapy and brain health, highlighting its importance since women are more susceptible to Alzheimer's after menopause. If you are looking for the latest research on hormone replacement therapy and its potential benefits, this episode is for you. Dr. Sara Gottfried is a board-certified physician who graduated from Harvard and MIT. She practices evidence-based integrative, precision, and Functional Medicine. Dr. Gottfried is the author of four New York Times bestselling books about trauma, hormones, and health. Dr. Mary Claire Haver is board-certified in Obstetrics and Gynecology and is a Certified Culinary Medicine Specialist. She is the New York Times bestselling author of The New Menopause. Lisa Mosconi, PhD, is an associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine and the director of the Women's Brain Initiative and the Alzheimer's Prevention Clinic. She is the New York Times bestselling author of The XX Brain and Brain Food. In this compilation episode, Dhru and his guests dive into (audio version / Apple Subscriber version): Women's Lives After the Age of 40 (1:46 / 1:46) Traditional Symptoms, Treatment, and What Causes the Fears (9:38 / 6:10) Perimenopause and Symptoms You May Not Realize Are Correlated (15:49 / 12:30) The Charlie Angels of Hormones (22:39 / 17:20) Women Are Living Longer but Not as Healthfully in the Last Third of Their Lives (31:49 / 26:30) Why Dr. Mary Claire Feels Medicine Is Up-to-Date on Women's Health (33:30 / 27:44) Fears of Breast Cancer (35:50 / 29:46) The Protective Effects of Estrogen (40:14 / 34:55) What Kind of Practitioner to Look For, and Is HRT Suitable for You (43:10 / 37:42) Testing, Dose and Timing (47:49 / 42:30) Dr. Lisa Mosconi's Views on HRT Research ( (58:49 / 53:30) HRT, Brain Health, and Reducing the Risk of Alzheimer's (1:03:49 / 58:30) Also Mentioned in this episode: The Charlie's Angels of Hormones Dr. Mosconi's Slideshow This episode is brought to you by Cozy Earth, One Skin, and Manukora. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP. Right now, One Skin is offering my community 15% off; just go to oneskin.co and use coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves. Upgrade to the creamiest honey, packed with antioxidants and prebiotics. Just go to manukora.com/dhru to get $25 off the Starter Kit and boost your energy, immunity, and digestive health today! Learn more about your ad choices. Visit megaphone.fm/adchoices
Navigating Neurology, Alzheimer's Prevention, and Lifestyle Interventions This episode of Trailblaze features Dr. Richard S. Isaacson who is the Founder of the Alzheimer's Prevention Clinic at Weill Cornell Medicine and NewYork-Presbyterian, the Director of Research at the Institute for Neurodegenerative Diseases in Florida, and the Director of the Precision Prevention Program Atria Institute New York / Palm Beach. In this episode, we trace the origins of Dr. Isaacson's medical and entrepreneurial career, from early aspirations to the specialized field of neurology, with a focus on Alzheimer's disease. Isaacson shares the groundbreaking work taking place at the Alzheimer's Prevention Clinic as he sheds light on its unique approach compared to traditional methods. As a vocal advocate for lifestyle interventions to combat neurodegenerative diseases with a TED talk on the topic, he shares the most effective lifestyle changes and the simplest actions that the average person can take to improve their health in the long run. We dive into stories of resilience from Dr. Isaacson's career, as he shares significant hurdles faced in research and clinical work. He describes the moments when perseverance proved essential, shaping a career dedicated to understanding and combating neurological diseases. Dr. Isaacson provides unique insights into the changing public perception of neurological diseases, and the role of media in spreading awareness and educating the public on health issues, particularly preventable diseases. Dr. Richard S. Isaacson is a pioneering neurologist with a focus on the treatment and prevention of Alzheimer's disease. He is the Founder and Former Director of the Alzheimer's Prevention Clinic, a first-of-its-kind in the world, at Weill Cornell Medicine & New York Presbyterian, where he was also Assistant Dean of Faculty Development and Associate Professor of Neurology. Prior to this, Dr. Isaacson was Associate Professor of Clinical Neurology and Vice Chair for Education at the University of Miami Miller School of Medicine. Dr. Isaacson has also previously served as Director of the Center for Brain Health at Florida Atlantic University Schmidt College of Medicine, and as Associate Medical Director of the Wien Center for Alzheimer's Disease and Memory Disorders at Mount Sinai. Connect with Dr. Richard Isaacson FAU Center for Brain Health Book: The Alzheimer's Prevention & Treatment Diet: Using Nutrition to Combat the Effects of Alzheimer's Disease Richard S. Isaacson Profile at Atria Meet Neurologist Dr. Richard Isaacson | NewYork-Presbyterian CNN Opinion: Why aren't doctors telling patients these simple ways to reduce the risk of dementia? Thank you for listening to Trailblaze! Share your thoughts about this episode of Trailblaze on social media: Twitter: https://twitter.com/AnthonyLacavera Instagram: https://instagram.com/anthony.lacavera LinkedIn: https://linkedin.com/in/anthonylacavera For more about Anthony Lacavera and to subscribe to the mailing list visit https://anthonylacavera.com. This episode was recorded on September 8, 2023.Trailblaze is produced by CreatorClub. Create your podcast at https://creatorclubstudios.com.
This playlist features live interviews recorded by Oncology Data Advisor at the 49th Annual Oncology Nursing Society (ONS) Congress in Washington, DC. For more information, visit OncData.com.
This episode is brought to you by BiOptimizers, Lumebox, and AquaTru.Women can spend up to 40% of their lives in menopause, and we know that they often experience changes in their mood, cognition, and overall brain health during this time. But these changes aren't discussed openly or discussed with no helpful solutions, leaving women feeling hopeless, alone, or unsupported. Today's guest is a brain researcher here to shed light on the changes during this time and what we can do to support women entering this phase. Today, on the Dhru Purohit Show, Dhru sits down with Dr. Lisa Mosconi to discuss what happens to a woman's brain when she goes through menopause and the connection to Alzheimer's disease. Dr. Mosconi shares how to care for women's brains during puberty, pregnancy, and menopause, how to prevent dementia and the lifestyle habits that can help women navigate the transition into menopause. Lisa Mosconi, PhD, is an associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine and the director of the Women's Brain Initiative and the Alzheimer's Prevention Clinic at Weill Cornell Medicine/NewYork-Presbyterian Hospital. She is also the New York Times bestselling author of The XX Brain and Brain Food. In this episode, Dhru and Dr. Mosconi dive into (audio version / Apple Subscriber version):What happens to the brain during menopause (0:00:20 / 0:00:20)Research as validation for women's experience (13:40 / 10:40)Brain changes during the 3Ps in a woman's life (16:39 / 13:00)Life contentment during perimenopause and menopause (20:11 / 16:51)Epigenetic's role in menopause (26:03 / 22:34)Lifestyle changes that are critical for optimal brain health (31:15 / 27:45)Three types of exercise for menopause and what they activate (37:34 / 33:32)What is menopause and when does perimenopause start (45:06 / 41:18)Lifestyle factors that cause the early onset of puberty (52:36 / 48:50)Environmental toxins that Dr. Mosconi removed from her home (57:30 / 53:35)Whole foods diet, fiber, and protein for optimal health (1:00:00 / 56:08)The research behind Hormone Replacement Therapy (1:21:32 / 1:17:22)Also mentioned in this episode:Dr. Mosconi's Slideshow The Menopause BrainGo to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order and up to 2 travel-size bottles of Magnesium Breakthrough for a limited time.Lumebox is offering my community $260 off their FDA-approved portable Red Light device! That's over 40% off! Go to thelumebox.com/dhru and get your Red Light device. AquaTru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter/ and get $100 off when you try AquaTru for yourself. Hosted on Acast. See acast.com/privacy for more information.
“It's important to realize that yes, menopause can come with symptoms, but the symptoms are not alien symptoms. We've seen them before. We've seen them at puberty. We've seen them at pregnancy, if you've been pregnant. We've been there before. And I like to say that menopause is just another tune that we learn to dance to, right? We can do it. We will navigate it. The point is let's make sure that we have the right information, that we understand how it works and that we're aware of the solutions because there are so many women who decide how to navigate menopause based on information that is not unfortunately accurate, it is not up to date. So a lot of decisions are really based on fear rather than facts and then there's regret.” So says neuroscientist Lisa Mosconi, PhD, who currently has 11 grants—including four from the NIH—to study Alzheimers, menopause, and the female brain. Dr. Mosconi is an Associate Professor of Neuroscience in Neurology and Radiology at Weill Cornell Medicine (WCM), and the Director of the Alzheimer's Prevention Program at WCM/NewYork-Presbyterian Hospital. The program includes the Women's Brain Initiative, the Alzheimer's Prevention Clinic, and the Alzheimer's Prevention Clinical Trials Unit. There are many things to love about Dr. Mosconi and her work—one, that she's focused on an underserved group, i.e. women, but also because her insights dramatically expand the way we've been conditioned to understand these hormonal shifts in our lives. The picture she paints of the female brain is not only fascinating, but it's inspiring: As we age and move through stages, our brains continually remodel, becoming leaner, meaner, and more empathic. The female brain is…formidable. There are also many things we can do to make these turbulent transitions slightly smoother sailing, which we dive into throughout our conversation. Let's turn to it now. MORE FROM LISA MOSCONI, PhD: The Menopause Brain: New Science Empowers Women to Navigate the Pivotal Transition with Knowledge and Power The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease Brain Food: The Surprising Science of Eating for Cognitive Power Lisa's Website Follow Lisa on Instagram To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
Lisa Mosconi, PhD, is an associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine and the director of the Women's Brain Initiative and the Alzheimer's Prevention Clinic at Weill Cornell Medicine/NewYork-Presbyterian Hospital. Her latest book, The Menopause Brain: New Science Empowers Women to Navigate the Pivotal Transition with Knowledge and Confidence, is out now. 15 Daily Steps to Lose Weight and Prevent Disease PDF: https://bit.ly/46XTn8f - Get my FREE eBook now! Become a Genius Life Premium Member! Learn more: http://thegeniuslife.com This episode is proudly sponsored by: LifeForce is a powerful, at-home biomarker testing solution (they test important biomarkers like ApoB, LDL, A1C, hormones, and more!). Head to MyLifeForce.com and use code GENIUS for 15% off. BUBS Naturals makes my favorite collagen, pure and unflavored, perfect for mixing into any drink, soup, or even recipes! Your hair, skin, and nails will thank you. Visit BUBSNaturals.com and use code GENIUS for 20% off.
World-renowned neuroscientist Dr. Lisa Mosconi takes us on a profound exploration of menopause. Together with Dr. Stephanie, she delves into the intricate physiological and neurological changes that occur during the perimenopausal, menopausal, and postmenopausal phases.In this episode, you will learn about the metabolic, vasomotor, and neurological shifts reshaping women's brains, unravelling the mysteries behind hot flashes, mood swings, and cognitive alterations. You will also discover the evolutionary significance of menopause and the vital roles grandmothers play in human communities.From hormone replacement therapy nuances to empowering lifestyle interventions, this conversation offers invaluable insights for women navigating this transformative stage of life. Embark on a journey of understanding and empowerment, and gain a newfound appreciation for the resilience and adaptability of the female brain.Episode Overview:0:00 Intro/Teaser5:04 Unveiling the Menopause Brain15:08 The Neurological Impact of Menopause34:41 Neuronal Development and Puberty43:44 Pregnancy Brain Remodeling51:26 Evolutionary Significance of Menopause1:03:41 Neurological Changes Post-Menopause1:04:39 Hormone Replacement Therapy Considerations1:09:19 Estrogen and Progesterone Considerations1:11:46 Types of Progestogens and Progestins1:17:55 Hormone Options for Breast Cancer History1:20:22 Limitations and Alternatives of Hormone Therapy1:24:21 Future of Hormones: Designer Estrogens1:24:33 Lifestyle Modifications and Clinical Trials1:33:48 Exercise Routines and Preferences1:34:58 Importance of Greens and Nutrients1:39:20 Stress Reduction and Hormonal BalanceBio:Lisa Mosconi, PhD, is an associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine and the director of the Women's Brain Initiative and the Alzheimer's Prevention Clinic at Weill Cornell Medicine/NewYork-Presbyterian Hospital. A world-renowned neuroscientist with a PhD in neuroscience and nuclear medicine from the University of Florence in Italy, Mosconi was listed as one of the seventeen most influential living female scientists by The Times and called “the Mona Lisa of Neuroscience” by ELLE International. She is the New York Times bestselling author of The XX Brain and Brain Food.Website URL: https://www.lisamosconi.com/Resources mentioned:The Menopause Brain book - https://www.lisamosconi.com/the-menopause-brainMenopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition - https://pubmed.ncbi.nlm.nih.gov/34108509/Association of reproductive history with brain MRI biomarkers of dementia risk in midlife - https://pubmed.ncbi.nlm.nih.gov/34732544/More research - https://www.lisamosconi.com/researchWomen's Brain Initiative - https://neurology.weill.cornell.edu/research/womens-brain-initiativeWe are grateful for our sponsors:BODYBIOBodyBio PC is a liposomal phospholipid complex designed to nourish your cells for healthy aging, optimal brain function, gut health, a better metabolism, and more. Prioritizing your cellular health is absolutely foundational for your well-being as you age. You can get started and save 15% off your first order with code “BETTER” at checkout at https://bodybio.com/BETTERCAROL BIKEThis is my favourite cardio for speed drills! Five minutes and done! One of the coolest things about the CAROL Bike is that it is AI driven so it gives you custom workouts based on your very own fitness level. For a limited time, you can get $100 off a CAROL Bike. Use the code BETTER at https://carolbike.com.BEAM MINERALSIt's almost impossible to get all of your minerals from food alone (as much as you would like to). So, if you want to increase your mineral intake quickly and easily, try BEAM Minerals. Visit https://beamminerals.com/better and get 20% off sitewide.
I am delighted and honored today to interview Dr. Lisa Mosconi. She is an Associate Professor of Neuroscience in neurology and radiology at Cornell Medicine and Director of the Women's BRAIN Initiative and the Alzheimer's Prevention Clinic at Weill Cornell Medicine, New York Presbyterian Hospital. She is also a globally acclaimed neuroscientist with a Ph.D. in neuroscience and nuclear medicine and the author of the New York Times bestseller The XX Brain and, more recently, The Menopause Brain. In our conversation, we discuss how women's brains change during perimenopause and menopause, looking at the significance of puberty, pregnancy, and perimenopause, as well as the lack of medical research on women and medical gaslighting. We explore the concept of bikini medicine and its misconceptions regarding women's health and hormones alongside the crucial roles of hormones like estradiol, progesterone, and testosterone in our neuroendocrine system. Dr. Mosconi also provides insights into evolving menopausal treatments, including lifestyle interventions. Dr. Mosconi is an esteemed figure in neuroscience and a prominent voice in women's health. I am confident you will gain valuable insights and perspectives from my discussion with her today. IN THIS EPISODE YOU WILL LEARN: How women's brains change during perimenopause and menopause How the lack of information for young girls can lead to medical gaslighting and confusion during perimenopause Dr. Mosconi explains how a simple sugar is used as a tracer to track glucose metabolism in the brain during perimenopause Why brain changes during menopause may lead to mental fatigue and brain fog How the lack of training and research on menopause in medical residency programs leads to a poor understanding among clinicians Why women need to consider their brain and metabolic health during perimenopause Why estrogen is essential after menopause The benefits of HRT for menopausal women How stress impacts hormone production Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Lisa Mosconi On her website On Instagram The Menopause Brain will be released March 12th, 2024.
In this episode Dr Louise is joined by world-renowned neuroscientist Dr Lisa Mosconi, PhD. Dr Lisa is Director of the Alzheimer's Prevention Clinic and Women's Brain Initiative at Weill Cornell Medicine in New York and author of bestsellers The XX Brain and Brain Food. Dr Lisa was studying nuclear medicine and neuroscience when her grandmother and her grandmother's three sisters all developed Alzheimer's. Dr Lisa became interested in the cause of Alzheimer's and why women are more susceptible. Her research has shown that, rather than a disease of old age, it starts in midlife and menopause potentially plays a part. Dr Lisa discusses her most recent paper, which found that women who took hormones in midlife to treat their menopause symptoms were less likely to develop dementia than those who hadn't taken oestrogen. Finally, Dr Lisa shares three things to consider about female hormones: Oestrogen, and oestradiol in particular, is the master regulator of women's brains. It really is like saying that oestrogen is to your brain what fuel is for an engine. It keeps your brain running. Endogenous oestrogen (produced within your body) is different from exogenous oestrogen (synthetic). The bioidentical oestradiol is probably the best one to use because it really maps on the same circuits for your own endogenous oestrogen. I would love for all women to be able to make an informed decision about whether or not hormone therapy is a viable option for them. Many women who are eligible for HRT do not go on HRT out of fear and the fear comes from outdated information, mislabelling on some of the packages. Follow Dr Lisa on Instagram @dr_mosconi Click here to find out more about Newson Health
Maria Shriver, Women's Alzheimer's Movement at Cleveland Clinic founder, Sharon Malone, Alloy Women's Health medical adviser and Lisa Mosconi, director of the Alzheimer's Prevention Clinic at Weill Cornell Medicine joined the Global Women's Summit to discuss menopause, the brain and women's health. Then, self-made billionaire Jenny Just, Peak6 co-founder and managing partner, shares what poker can teach women about risk-taking and business strategy. Conversations recorded on Tuesday, Nov. 14, 2023.
Did you know researchers estimate that nearly two-thirds of those living with Alzheimer's in the United States are women? As this data continues to emerge, conversations surrounding brain health are as important as ever before, which is why I've decided to share a beloved episode from the archives where I'm joined by a leading voice in Neuroscience, bestselling author, and one of the most influential scientists of our time, Dr. Lisa Mosconi. Lisa is blowing the lid off of female brain health with her groundbreaking research on cognitive enhancement and Alzheimer's prevention, specifically in women. She provides us with a full access pass into what is truly going on in the female brain as we age and why understanding the unique risks and strengths of the XX brain is so incredibly important, no matter the year you were born. Consider this episode a roadmap to optimal, lifelong brain health. We discuss: The meaning of “bikini medicine,” why it hinders women's health research, and how Lisa is confronting this crisis The protective effects of cumulative estrogen exposure and the role of hormone replacement therapy in women's brain health How risk of memory loss and dementia can be prevented by using an integrative approach including appropriate medical care and lifestyle modifications involving diet, physical and intellectual fitness Testing recommendations to assess brain health, the Women's Brain Initiative and therapies to prevent, delay, and, minimize the risk of Alzheimer's disease Dr. Mosconi holds a PhD degree in Neuroscience and Nuclear Medicine and is an associate professor of Neuroscience in Neurology and Radiology at Weill Cornell Medicine/NY-Presbyterian Hospital, where she serves as director of the Alzheimer's Prevention Program. The program includes the Women's Brain Initiative, the Alzheimer's Prevention Clinic, and the Alzheimer's Prevention Clinical Trials Unit. She is ranked amongst the top 1% of scientists of the past 20 years by official metrics, and was listed as one of the 17 most influential living female scientists by The Times. She is the author of The New York Times, USA Today, Publishers Weekly, and Der Spiegel bestselling book The XX Brain (2020) and of the international bestseller Brain Food (2018). Find out more about the Women's Brain Initiative and testing here - neurology.weill.cornell.edu Thank you so much for taking the time to tune in to your body, yourself, and this podcast! Please share the love by sending this to someone in your life who could benefit from the kinds of things we talk about in this space. Make sure to follow along on Instagram @dr.avivaromm and go to avivaromm.com to join the conversation. Follow Lisa @dr_mosconi.
Dr. Danny Luger, a cardiologist at Rush Center for Prevention of Cardiovascular Disease, joins Lisa Dent to explain how he and Dr. Max Fitzgerald came up with the idea of opening a cardiac care prevention clinic that treats patients who don't have cardiovascular disease yet but have all the risk factors that may put them […]
This episode is brought to you by InsideTracker and AquaTru.Two out of every three Alzheimer's patients are women. Today, Alzheimer's is as real a threat to women's health as breast cancer is. A 45-year-old woman has a one-in-five chance of developing Alzheimer's during her remaining life, while a man of the same age only has a one-in-ten chance. What happens to women, and not to men, in midlife that could potentially trigger an Alzheimer's predisposition, and that could potentially initiate Alzheimer's?On today's mini-episode, Dhru sits down with Dr. Lisa Mosconi to talk about the research on why women represent two-thirds of the Alzheimer's population. They discuss what happens to a woman's brain when she goes through menopause and the connection to Alzheimer's disease. They also talk about how to care for women's brains, how to prevent dementia, and the groundbreaking research that Dr. Mosconi and her team are conducting at the Alzheimer's Prevention Clinic. Dr. Mosconi is the director of the Women's Brain Initiative and associate director of the Alzheimer's Prevention Clinic at Weill Cornell Medical College, where she serves as an associate professor of neuroscience in neurology and radiology. In addition, she is an adjunct faculty member at the NYU Department of Psychiatry and the author of Brain Food and The XX Brain. In this episode we dive into: -The statistics on Alzheimer's disease, and its impact on women-The early changes we are seeing in the female brain midlife-What happens to a woman's brain when she goes through menopause-The impact of diet on our hormones and brain health-What women can do to prevent dementia Listen to the full episode here. For more on Dr. Lisa Mosconi, follow her on Instagram @dr_mosconi and through her website, lisamosconi.com. Learn more about The Women's Brain Initiative here. You can find her book, The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease, here.This episode is brought to you by InsideTracker and AquaTru.InsideTracker provides detailed nutrition and lifestyle guidance based on your individual needs. Right now, they're offering my podcast community 20% off. Just go to insidetracker.com/DHRU to get your discount and try it out for yourself.AquaTru is the primary water filter I use at home and in my office. Right now, they are offering my community an amazing deal. Get $150 off your filter at drhyman.com/filter today. Hosted on Acast. See acast.com/privacy for more information.
Did you know researchers estimate that nearly two thirds of those living with Alzheimer's in the United States are women? This week, I am joined by the Mona Lisa of Neuroscience, bestselling author, and one of the most influential scientists of our time, Dr. Lisa Mosconi. Lisa is blowing the lid off of female brain health with her groundbreaking research on cognitive enhancement and Alzheimer's prevention, specifically in women. She provides us with a full access pass into what is truly going on in the female brain as we age, and why understanding the unique risks and strengths of the XX brain is so incredibly important, no matter the year you were born. Consider this episode a roadmap to optimal, lifelong brain health. We discuss: The meaning of “bikini medicine,” why it hinders women's health research, and how Lisa is confronting this crisis The protective effects of cumulative estrogen exposure and the role of hormone replacement therapy in women's brain health How risk of memory loss and dementia can be prevented by using an integrative approach including appropriate medical care and lifestyle modifications involving diet, physical and intellectual fitness Testing recommendations to assess brain health, the Women's Brain Initiative and therapies to prevent, delay, and, minimize the risk of Alzheimer's disease Dr. Mosconi holds a PhD degree in Neuroscience and Nuclear Medicine and is an associate professor of Neuroscience in Neurology and Radiology at Weill Cornell Medicine/NY-Presbyterian Hospital, where she serves as director of the Alzheimer's Prevention Program. The program includes the Women's Brain Initiative, the Alzheimer's Prevention Clinic, and the Alzheimer's Prevention Clinical Trials Unit. She is ranked amongst the top 1% of scientists of the past 20 years by official metrics, and was listed as one of the 17 most influential living female scientists by The Times. She is the author of The New York Times, USA Today, Publishers Weekly, and Der Spiegel bestselling book The XX Brain (2020) and of the international bestseller Brain Food (2018). Find out more about the Women's Brain Initiative and testing here - neurology.weill.cornell.edu Thank you so much for taking the time to tune in to your body, yourself, and this podcast! Please share the love by sending this to someone in your life who could benefit from the kinds of things we talk about in this space. Make sure to follow along on Instagram @dr.avivaromm and go to avivaromm.com to join the conversation. Follow Lisa @dr_mosconi.
Your brain is a powerful force that regulates so many functions and processes in your body. Everything from memory and emotion to temperature and metabolism are controlled by this complex and dynamic organ. Because of the expansive nature of the human brain, the field of neuroscience is vast and ever-evolving. Dr. Lisa Mosconi is a world-renowned neuroscientist who is ranked amongst the top 1% of scientists in the past 20 years. Dr. Mosconi studies the fascinating and growing intersection of neuroscience and nutrition, including how what we eat impacts our brain health and can ultimately determine our susceptibility to neurodegenerative diseases. She is the director of the Women's Brain Initiative and the associate director of the Alzheimer's Prevention Clinic at Weill Cornell Medicine, an adjunct faculty member at the NYU Department of Psychiatry, and the author of two incredible bestselling books, Brain Food and The XX Brain. On today's show, you're going to hear two powerful excerpts from previous interviews with Dr. Lisa Mosconi. She's sharing the science on a wide variety of topics under the umbrella of brain health—including how Alzheimer's disease develops over time, what your brain is made of and what nutrients it needs to survive, how men and women's brains differ, and so much more. We can all learn more about how to nourish and protect our brain health, and I hope this episode empowers you to do just that. Enjoy! In this episode you'll discover: What the HPA axis is, and how it works. The relationship between your hypothalamus and your metabolic rate. What nuclear medicine is. The surprising connection between Alzheimer's disease and genetics. What neuronutrition is, and how the blood-brain barrier works. A major differentiating factor between brain cells and other cells in the body. How many nutrients the brain has access to. Why your brain itself cannot feel pain. What a brain reserve is. An important distinction between dietary cholesterol and cholesterol in the brain. What compounds your brain is made of. Specific nutrients your brain needs for optimal health. Why long-chain polyunsaturated fats are critical for brain function. The link between menopause and Alzheimer's disease. Why you should avoid xenoestrogens. How women have been systematically excluded from research. Why the XX chromosomes are related to brain function. What estradiol is. How Alzheimer's disease develops over time. The role estrogen has in the brain. What the number one cause of early menopause is. Why hormone replacement therapy needs to be individualized. The power of protecting your brain with antioxidants. Which vitamins are most important for combating oxidative stress. Why your brain needs carbohydrates. Items mentioned in this episode include: PiqueLife.com/model -- Use code MODEL at checkout for 10% off! Organifi.com/Model -- Use the coupon code MODEL for 20% off! Eating for Cognitive Power with Dr. Lisa Mosconi – Episode 319 Secrets of the Female Brain with Dr. Lisa Mosconi – Episode 402 Natural Treatments for Fibroid Tumors – Episode 148 The XX Brain by Dr. Lisa Mosconi Brain Food by Dr. Lisa Mosconi Skittles Highway Spill – Huff Post Connect with Dr. Lisa Mosconi Website / Instagram Join TMHS Facebook community - Model Nation Be sure you are subscribed to this podcast to automatically receive your episodes: Apple Podcasts Stitcher Spotify Soundcloud *Download Transcript
To have a healthy outlook on life you need a healthy mind. Do you know what you are feeding your brain and your body? Food production and additives have changed over the years, and not for the better. Diane shares a quote from Dr. Lisa Mosconi's, book "Brain Food" and some tips on what to look for when shopping for your groceries. Alzheimers and Dementia affect over 46 million people in the world and is expected to rise to 132 Million by the year 2050 as stated in the book. These numbers are increasing at a rapid pace. You have a choice on what you consume and what you feed your family. Science tells us that our diet does influence our physical and mental health. Make informed decisions for maximum cognitive capacity. Live an Inspired Life! #BrainHealth #Flourish #Dementia Dr. Mosconi is an Associate Director at the Alzheimer's Prevention Clinic located at the Weill Cornell Medical College in New York. Disclaimer from Dr. Mosconi's book: "Neither the publisher nor the author is engaged in rendering professional advice or services to the individual reader. The ideas, procedures and suggestions contained in this book are not intended as a substitute for consulting with your physician. All matters regarding your health require medical supervision. Neither the author nor the publisher shall be liable or responsible for any loss or damage allegedly arising from any information or suggestion in this book." This disclaimer is equally applicable to the Flourish show and Diane Planidin.
If you think men's and women's brains are different, you couldn't be more right. And knowing the gender differences in nutrition and exercise can help all of us have a better and healthier life. Today our guest is Dr. Lisa Mosconi, a Ph.D. is the founder and director of the Women's Brain Initiative, associate director of the Alzheimer's Prevention Clinic, and associate professor of Neuroscience in Neurology and Radiology at Weill Cornell Medicine is the one who is going to help us with that today. In this episode, Vishen Lakhiani and Dr. Lisa Mosconi will be discussing how our genetics, environment, and lifestyle shape our brains, focusing especially on women. You'll use this knowledge right now, tomorrow, and over the course of your lifetime. Dr. Lisa Mosconi, Ph.D., is the Director of the Women's Brain Initiative and Associate Director of the Alzheimer's Prevention Clinic at Weill Cornell Medical College (WCMC)/NewYork-Presbyterian Hospital, where she serves as an Associate Professor of Neuroscience in Neurology and Radiology. She is also an adjunct faculty member at the Department of Psychiatry at New York University (NYU) School of Medicine. Dr. Mosconi holds a Ph.D. degree in Neuroscience and Nuclear Medicine and is a certified Integrative Nutritionist and holistic healthcare practitioner. Dr. Mosconi's work has spoken at over 80 international conferences leading to press releases involving TV and radio networks worldwide (CNN, CBS, NBC, the Today Show, the Doctors show, etc.), and major print media including Associated Press, Reuters, the New York Times, the Washington Post, Forbes, The Wall Street Journal, Bloomberg, Psychology Today, and several international outlets. She is the author of the instant New York Times bestseller THE XX BRAIN: the Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease [Avery/ Penguin Random House] and of BRAIN FOOD: The Surprising Science of Eating for Cognitive Power [Avery/ Penguin Random House]. Listen out for: - How are male and female brains different. - The connection between menopause and women's brains. - Things women can do to understand their brains through menopause. - Gender differences in nutrition and exercise that women need to be aware of. - The connection between stress and hormones. - Nutrients that women need to pay attention to. - Live bonus Q&A session. Bonus: - Learn how to transform your eating habits once and for all with this FREE Mindvalley Masterclass
School of Greatness Podcast Notes Key Takeaways There are differences in the brain by sex: the X chromosome has nearly 1,000 more genes than the Y hormone (men have XY chromosomes, women have XX chromosomes)Women’s brains use more estrogen, men’s brains use more androgens There is evidence that plant-based diets are effective in supporting brain health in women Five most antioxidant foods: (1) coffee (especially double espresso); (2) berries; (3) lemon in hot water first thing in the morning; (4) omega-3s; (5) dark leafy greens and cruciferous vegetablesBecause of testosterone, men’s metabolism supports fat breakdown more efficiently than women’s bodiesFor brain health, stay away from processed foods: the brains of people on the Standard American Diet look older than those on the Mediterranean diet based on brain scansWe should think of food as function, protection, and a tool to use for optimal healthWomen want to leverage lifestyle factors to delay the onset of menopause as much as possible so estrogen levels don’t fall off early and can continue to support brain health – avoid smoking, manage stress, eat whole foodsWomen who have hysterectomy or oophorectomy have a higher rate of Alzheimer’sSpring water has more electrolytes than purified water and better for hydration Read the full notes @ podcastnotes.org"It is this continuous exposure to food that makes diet the most important factor ever to affect our DNA."Today's guest is Dr. Lisa Mosconi. She’s the founder and director of the Women’s Brain Initiative, and associate director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine, where she serves as associate professor of Neuroscience in Neurology and Radiology. She is also the NYT bestselling author BRAIN FOOD and her new book, THE XX BRAIN.In this episode Lewis and Lisa discuss the differences between men and women’s brains and how they function, what we need in order to optimize our brain health, why Alzheimers is affecting so many of us, especially women and what we can do about it, and so much more!For more go to: www.lewishowes.com/1091Check out her books: www.lisamosconi.com/brainfood & www.lisamosconi.com/xxbrainThe Wim Hof Experience: Mindset Training, Power Breathing, and Brotherhood: https://link.chtbl.com/910-podA Scientific Guide to Living Longer, Feeling Happier & Eating Healthier with Dr. Rhonda Patrick: https://link.chtbl.com/967-podThe Science of Sleep for Ultimate Success with Shawn Stevenson: https://link.chtbl.com/896-pod
School of Greatness Podcast Notes Key Takeaways There are differences in the brain by sex: the X chromosome has nearly 1,000 more genes than the Y hormone (men have XY chromosomes, women have XX chromosomes)Women’s brains use more estrogen, men’s brains use more androgens There is evidence that plant-based diets are effective in supporting brain health in women Five most antioxidant foods: (1) coffee (especially double espresso); (2) berries; (3) lemon in hot water first thing in the morning; (4) omega-3s; (5) dark leafy greens and cruciferous vegetablesBecause of testosterone, men’s metabolism supports fat breakdown more efficiently than women’s bodiesFor brain health, stay away from processed foods: the brains of people on the Standard American Diet look older than those on the Mediterranean diet based on brain scansWe should think of food as function, protection, and a tool to use for optimal healthWomen want to leverage lifestyle factors to delay the onset of menopause as much as possible so estrogen levels don’t fall off early and can continue to support brain health – avoid smoking, manage stress, eat whole foodsWomen who have hysterectomy or oophorectomy have a higher rate of Alzheimer’sSpring water has more electrolytes than purified water and better for hydration Read the full notes @ podcastnotes.org"It is this continuous exposure to food that makes diet the most important factor ever to affect our DNA."Today's guest is Dr. Lisa Mosconi. She’s the founder and director of the Women’s Brain Initiative, and associate director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine, where she serves as associate professor of Neuroscience in Neurology and Radiology. She is also the NYT bestselling author BRAIN FOOD and her new book, THE XX BRAIN.In this episode Lewis and Lisa discuss the differences between men and women’s brains and how they function, what we need in order to optimize our brain health, why Alzheimers is affecting so many of us, especially women and what we can do about it, and so much more!For more go to: www.lewishowes.com/1091Check out her books: www.lisamosconi.com/brainfood & www.lisamosconi.com/xxbrainThe Wim Hof Experience: Mindset Training, Power Breathing, and Brotherhood: https://link.chtbl.com/910-podA Scientific Guide to Living Longer, Feeling Happier & Eating Healthier with Dr. Rhonda Patrick: https://link.chtbl.com/967-podThe Science of Sleep for Ultimate Success with Shawn Stevenson: https://link.chtbl.com/896-pod
"It is this continuous exposure to food that makes diet the most important factor ever to affect our DNA."Today's guest is Dr. Lisa Mosconi. She’s the founder and director of the Women’s Brain Initiative, and associate director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine, where she serves as associate professor of Neuroscience in Neurology and Radiology. She is also the NYT bestselling author BRAIN FOOD and her new book, THE XX BRAIN.In this episode Lewis and Lisa discuss the differences between men and women’s brains and how they function, what we need in order to optimize our brain health, why Alzheimers is affecting so many of us, especially women and what we can do about it, and so much more!For more go to: www.lewishowes.com/1091Check out her books: www.lisamosconi.com/brainfood & www.lisamosconi.com/xxbrainThe Wim Hof Experience: Mindset Training, Power Breathing, and Brotherhood: https://link.chtbl.com/910-podA Scientific Guide to Living Longer, Feeling Happier & Eating Healthier with Dr. Rhonda Patrick: https://link.chtbl.com/967-podThe Science of Sleep for Ultimate Success with Shawn Stevenson: https://link.chtbl.com/896-pod
One in three cases of Alzheimer's disease may be preventable, but some cases are quite predictable. Dr. Richard Isaacson, Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine, explains how scientists look at genetics, lifestyle, and medical history to evaluate an individual's risk of developing the disease. Plus... how your belly size affects your memory center
Welcome to the NeurologyLive Mind Moments podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. In this episode, we're joined by Lon Schneider, MD, MS, Della Martin Chair in Psychiatry and Neuroscience, University of Southern California Keck School of Medicine; Marwan Sabbagh, MD, director, Lou Ruvo Center for Brain Health, Cleveland Clinic; Stephen Salloway, MD, MS, director, Neurology and the Memory and Aging Program, Butler Hospital; Richard S. Isaacson, MD, director, Alzheimer’s Prevention Clinic, Weill Cornell Medicine; and Anton Porsteinsson, MD, director, Alzheimer's Disease Care, Research, and Education Program, University of Rochester. Each of these experts provided their perspective and insight into what’s been happening in the conversations around aducanumab and why there is some controversy around its clinical trial data, as well as how all of this speaks to the intricacies and difficulties in actually conducting clinical trials in Alzheimer disease. Part 1 – Support, Skepticism, and Statistics: The Aducanumab Saga (https://www.neurologylive.com/view/support-skepticism-and-statistics-the-aducanumab-saga) Part 2 – Compounding Challenges: Conducting Clinical Trials in Alzheimer Disease (https://www.neurologylive.com/view/compounding-challenges-conducting-clinical-trials-in-alzheimer-disease) Thanks for listening to the NeurologyLive Mind Moments podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com (http://neurologylive.com/) .
Women of African descent are more likely to be diagnosed with aggressive breast cancers than white women and are more likely to die from their disease regardless of its type or stage. For those living in remote or low-resource areas, limited access to screening and genetic testing make improving outcomes even more challenging. In this episode of our podcast, Dr. Funmi Olopade, talks about her work in Africa and Chicago, the critical importance of precision medicine, and why she’s “impatient” about eliminating barriers to breast cancer care around the world. Dr. Olopade, a BCRF investigator since 2001, serves as the founding director of the Cancer Risk and Prevention Clinic and associate dean for global health, both at the University of Chicago.
The brains of men and women are more alike than they are different. That said, there are some unique characteristics of the female brain that are highly significant. When we fail to recognize these differences, we put women at greater risk for premature aging, cognitive decline and dementia. This episode is drawn from a radio interview Roger and I did with Robin Gunn, who hosts the Oklahoma Senior Journal radio show in Oklahoma City. We anchored the discussion around what I have learned from the book THE XX BRAIN by Lisa Mosconi, PhD. Mosconi is the director of the Women's Brain Initiative and associate director of the Alzheimer's Prevention Clinic at Weill Cornell Medical College. With this podcast we begin to explore how women's brains differ, how those differences affect their lives and their risks for brain health problems, and what can be done to lower the risks. Chapters: IntroductionWhy should we focus on women's brains?Do women get equal brain health treatment?Genetic differencesHormonal differencesTransformations in a woman's lifeWomen's risk of getting dementiaArtificial and natural menopauseMenopause Hormone TherapyHow woman can lower risks and discomfortConclusion
Peter is joined by writer, director, actress, and founder of HFC, Lauren Miller Rogen, and previous podcast guest and director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and New York-Presbyterian, Dr. Richard Isaacson. In this episode, Lauren tells the heartbreaking story of watching members of her family succumb to Alzheimer’s disease (AD) which motivated her to proactively address her own risk with Richard’s guidance. Richard discusses the various genetic and lifestyle factors that influence the risk of AD and uses Lauren’s unique situation to explain how he diagnoses patients and personalizes care. They go through Lauren’s protocol of preventative measures that have already produced marked results, and end with the uplifting message that one’s genetic predisposition does not seal one's fate. We discuss: Lauren’s deep family history of Alzheimer’s disease (3:10); The influence of genetics, epigenetics, and lifestyle on Alzheimer’s disease risk (13:45); Lauren’s mother’s disease progression and the enormous stress it causes for family members (24:30); The various manifestations of Alzheimer’s disease depending on the location of pathology (29:30); The three stages of Alzheimer's disease (34:45); Richard’s deep exploration into Lauren’s family history revealing clues about a diagnosis and a roadmap to successful disease mitigation (39:15); How exercise reduces Alzheimer’s disease risk, and the different risk between males and females (58:00); Why knowing your APOE status is important, and whether certain people should be wearier of head trauma (1:08:00); How Richard uses genetic testing to personalize care (1:14:45); The “ABCs” of Alzheimer’s prevention, lifestyle interventions, and Lauren’s personal protocol for reducing her risk (1:21:45); Unique treatment for people with the ApoE4 variant (1:36:30); Richard’s mixed opinion on CBD and THC as a tool for disease prevention (1:40:00); Cognitive testing procedures, and how Lauren’s tests furthered her commitment to her disease prevention protocol (1:41:45); The relevance of sense of smell and hearing in Alzheimer’s disease risk and prevention (1:50:00); The emotional benefit of knowing you have control over your mental and physical health (1:57:30); HFC—a charitable organization founded by Lauren and Seth (2:00:15); and More. Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/laurenmillerrogen-richardisaacson/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.
Women's brain health remains one of the most under researched, under diagnosed and under undertreated fields of medicine. Women are twice as likely as men to develop Alzheimer’s and twice as likely to become anxious or depressed. They are four times more likely to suffer with headaches and migraines and they are more prone to brain tumours and strokes than men. Today’s guest says this is a clear indication of functional differences between female and male brains. And she’s made it her life’s work to learn more about it.Neuroscientist Dr Lisa Mosconi is director of the Women’s Brain Initiative and works at the Alzheimer’s Prevention Clinic at Weill Cornell Medical College, US, where she studies how genetics, lifestyle and nutrition shape brain health, particularly in women.Lisa describes her frustration at constantly being told by peers that the reason Alzheimer’s was more prevalent in women was simply because they live longer, and it’s a disease of ageing. We discuss her ground-breaking research that has exposed this bias, finding dementia brain changes can actually begin in midlife, triggered by declining oestrogen during perimenopause. Worrying as that might sound, this discovery will enable women to take control of their risk at a much earlier age. Lisa goes on to share plenty of practical, evidence-based advice to help you do that.I was really moved hearing Lisa talk about the beautiful changes that happen in the female brain during pregnancy and post-partum. It’s a new take on the idea of ‘Mummy brain’ and will be validating for all mothers out there to hear. She also gives a clear and candid explanation of how perimenopause alters brain function. So many of my patients in their 40s and 50s are scared by changes like forgetfulness, brain fog and anxiety. If that’s you or someone you know, Lisa’s insights and advice will be really empowering.I’m a passionate advocate for women’s health equality. Yet chatting with Lisa made me realise how much more work we all have to do to get topics like these out there and understood. This conversation is relevant to all of us, women and men alike. I hope it gets you thinking and talking more. Show notes available at drchatterjee.com/129Follow me on instagram.com/drchatterjee/Follow me on facebook.com/DrChatterjee/Follow me on twitter.com/drchatterjeeukDISCLAIMER: The content in the podcast and on this webpage is not intended to constitute or be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or other qualified health care provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website. See acast.com/privacy for privacy and opt-out information.
Did you know that Alzheimer’s is a preventable disease and not a disease of old age? We tend to associate it with the elderly because that’s when clinical symptoms manifest, but in reality, Alzheimer’s begins with negative changes in the brain at least a decade prior. More often than not, in middle age.In this mini-episode, Dhru speaks with Dr. David Perlmutter, Dr. Lisa Mosconi, and Dr. Dale Bredesen about why Alzheimer’s is a preventable disease, the lifestyle factors that can set the stage for Alzheimer’s years from now, the statistics on Alzheimer’s disease and its impact on women, and what you can do today to prevent cognitive decline. Dr. David Perlmutter is a board-certified neurologist and four-time New York Times best selling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition and as a member of the Editorial Board for the Journal of Alzheimer’s Disease. His books include the #1 New York Times bestseller Grain Brain, The Surprising Truth About Wheat, Carbs and Sugar, with over 1 million copies in print. His latest book, Brain Wash, was co-written with his son, Dr. Austin Perlmutter. Dr. Lisa Mosconi is the director of the Women's Brain Initiative and associate director of the Alzheimer's Prevention Clinic at Weill Cornell Medical College, where she serves as an associate professor of neuroscience in neurology and radiology. In addition, she is an adjunct faculty member at the NYU Department of Psychiatry, and the author of Brain Food and The XX Brain.Dr. Dale Bredesen is internationally recognized as an expert in the mechanisms of neurodegenerative diseases, such as Alzheimer's disease, and the author of the New York Times bestseller, The End of Alzheimer's. He held faculty positions at UCSF, UCLA, and the University of California, San Diego, and directed the Program on Aging at the Burnham Institute before coming to the Buck Institute in 1998 as its founding president and CEO. He is currently a professor at UCLA and the Chief Science Officer At Apollo Health.Find Dhru’s full-length conversation with Dr. David Perlmutter here: https://broken-brain.lnk.to/DrDavidPerlmutter/Find Dhru’s full-length conversation with Dr. Lisa Mosconi here: https://broken-brain.lnk.to/DrLisaMosconi/Find Dhru’s full-length conversation with Dr. Dale Bredesen here: https://broken-brain.lnk.to/DrDaleBredesen/For more on Dhru Purohit, be sure to follow him on Instagram @dhrupurohit, on Facebook @dhruxpurohit, on Twitter @dhrupurohit, and on YouTube @dhrupurohit. You can also text Dhru at (302) 200-5643 or click here https://my.community.com/dhrupurohit.Interested in joining Dhru’s Broken Brain Podcast Facebook Community? Submit your request to join here: https://www.facebook.com/groups/2819627591487473/.This episode is brought to you by the Pegan Shake.How you start your morning sets the tone for the day. I’m a huge fan of morning routines, because I think they can transform your ability to focus, sleep well, and get the most out of your day, especially in this busy, modern world. What I’ve found is that the best way to begin your day is to feed your body the right information or the right nutrients. That’s why Dr. Mark Hyman and I created the Pegan Shake. It’s a nutritionally packed morning blend designed to support healthy blood sugar, energy, and brain power. It contains some of my most favorite brain boosting foods like MCT and avocado. It also features acacia fiber for healthy gut function and collagen, pumpkin, and pea protein to support muscle synthesis. Check it out at getfarmacy.com/peganshake. See acast.com/privacy for privacy and opt-out information.
Dr. Lisa Mosconi joins the show. Dr. Lisa Mosconi, PhD, is the Director of the Women's Brain Initiative and Associate Director of the Alzheimer's Prevention Clinic at Weill Cornell Medical College (WCMC)/NewYork-Presbyterian Hospital, where she serves as an Associate Professor of Neuroscience in Neurology and Radiology. She is also an adjunct faculty member at the Department of Psychiatry at New York University (NYU) School of Medicine, and t the Department of Nutrition at NYU Steinhardt School of Nutrition and Public Health. Formerly, Dr. Mosconi was an Assistant Professor of the NYU Department of Psychiatry, where she founded and was the director of the Nutrition & Brain Fitness Lab, and served as the director of the Family History of Alzheimer's disease research program. Brain Candy Snippets: Nutrition for the brain The role of inflammation in the brain The latest brain research Hormones and the brain Her new book about Alzheimers And much more… Link to more information about Dr. Mosconi: WEBSITE
Dr. Lisa Mosconi joins the show. Dr. Lisa Mosconi, PhD, is the Director of the Women’s Brain Initiative and Associate Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medical College (WCMC)/NewYork-Presbyterian Hospital, where she serves as an Associate Professor
Today’s podcast is with the wonderful Dr Lisa Mosconi, PhD, author of the brand new book “The XX Brain” and the director of the Women's Brain Initiative and the associate director of the Alzheimer's Prevention Clinic at Weill Cornell Medical College, where she also serves as associate professor of Neuroscience in Neurology and Radiology. She is a board-certified integrative nutritionist and holistic healthcare practitioner and somebody who is championing better, more inclusive research that recognises the distinctiveness of the female brain for improved clinical outcomes. I loved her first book “Brain food”, and this new book is an incredible addition to her literary works and a way to empower women across the world to make more evidence based informed choices about their health and wellbeing with respects to brain health. On Today’s podcast we talk about:The statistics regarding how women are far more likely than men to suffer from anxiety, depression, migraines, poor recovery from brain injuries, Autoimmune conditions like MS and Alzheimer's disease.What she refers to as Bikini MedicineHer personal Story of Alzheimer’s in her familyWhat the ‘Women’s Brain initiative’ aims to achieve in scienceHow women's brains age distinctly from men'sThe unique risks women faceHow memory lapses, depression, stress, insomnia and the increased risk of dementia are key issues during menopause that arise in the brain rather than the reproductive organsThe key brain-protective hormone: OestrogenAbandoning one size fits all medicine and embracing personalised medicine8 steps to improving women’s brain health including: Diet, Stress reduction, Sleep, harnessing the power of the Microbiome, deciding if HRT therapy is for you, Environmental toxins and supplementsDefinitely do check out Dr Lisa's book - “The XX Brain” - which is a brilliant read and full of super interesting and helpful and easy to understand information.All other social media links are noted here below.WebsiteTwitterInstagram See acast.com/privacy for privacy and opt-out information.
Lisa Mosconi holds a PhD degree in Neuroscience and Nuclear Medicine and is a certified Integrative Nutritionist and holistic healthcare practitioner. At Weil Cornel Medical College in New York, she is the Director of the Women’s Brain Initiative in the Department of Neurology, Associate Director of the Alzheimer’s Prevention Clinic, and Associate Professor of Neuroscience in Neurology and Radiology. She has published over 100 peer-reviewed papers in prestigious medical journals and is the author of 2 books, both of which she and Eric discuss in this episode: Brain Food: The Surprising Science of Eating for Cognitive Power and The XX Brain: The Groundbreaking Science Empowering Women To Maximize Cognitive Health and Prevent Alzheimer’s Disease.Spiritual Habits Group Program - Find Solid Ground In Shaky Times:Join Eric in this virtual, live group program to learn powerful Spiritual Habits to help you access your own deep wisdom and calm steadiness - even when the world feels upside down. Click here to learn more and sign up. Enrollment is open now through Sunday, July 19th, 2020Need help with completing your goals in 2020? The One You Feed Transformation Program can help you accomplish your goals this year.But wait – there’s more! The episode is not quite over!! We continue the conversation and you can access this exclusive content right in your podcast player feed. Head over to our Patreon page and pledge to donate just $10 a month. It’s that simple and we’ll give you good stuff as a thank you!In This Interview, Lisa Mosconi and I Discuss the Eating for Brain Health and…Her books, Brain Food: The Surprising Science of Eating for Cognitive Power and The XX Brain: The Groundbreaking Science Empowering Women To Maximize Cognitive Health and Prevent Alzheimer’s DiseaseHow the foods we eat contribute to our brain healthNeuronutrition: the science of how to nourish our brain via the foods we eatHow in our health, genes load the gun but lifestyle pulls the triggerFoods you eat have an almost immediate impact on the health and function of your brainThe damage that results to your brain from eating a Western dietThe brain health benefits of a Mediterranean dietThe importance of drinking water – especially to support your brainThat the human brain is 80% water and therefore is very sensitive to dehydrationThe most important foods and nutrients for brain healthThe beneficial role in the brain of Omega 3 fatty acids in addition to antioxidantsNutritional benefit of whole foods vs supplementsDetrimental nature of regular consumption of processed foodThat health should not be a privilege of the wealthyThe energy production and protective roles of estrogen in the brainThe unique properties of women’s health and women’s brainsHow to reduce your risk of Alzheimer’s disease and other forms of dementia through the foods you eatWhat women can do to support their brains The detrimental nature of chronic stress on women’s brainsLisa Mosconi Links:lisamosconi.comTwitterInstagramSeed: Scientifically validated, next-generation probiotics. Their mission: to bring much-needed precision, efficacy, and education to the global probiotics market. Go to www.seed.com/wolf or use promo code WOLF for 15% off your first month of The Daily Symbiotic.Talkspace: the online therapy company that lets you connect with a licensed therapist from anywhere at any time. Therapy on demand. Non-judgemental, practical help when you need it at a fraction of the cost of traditional therapy. Visit www.talkspace.com and enter Promo Code: WOLF to get $100 off your first month.Grammarly: The digital writing tool that you can rely on to get your message across clearly, effectively, and correctly. It works where you work: in Gmail, Google Docs, Slack and many other platforms. Get 20% off Grammarly Premium when you sign up at www.grammarly.com/feedIf you enjoyed this conversation with Lisa Mosconi on Eating for Brain Health, you might also enjoy these other episodes:Lisa Feldman BarrettFlorence Williams
Science is science, right? Unfortunately, this is not always the case, especially when it comes to women’s health. Our understanding of the human brain and body has been clouded by years of gender bias—for decades many scientists and doctors have assumed that men and women are really the same, except for the bits and bobs that can be covered by a bikini. Yet, as this podcast guest and renowned researcher Dr. Lisa Mosconi points out, this kind of “bikini science” has dramatic implications for women’s mental and physical health that go beyond our reproductive organs, affecting every part of the brain and body. Dr. Lisa Mosconi, PhD, is the Director of the Women’s Brain Initiative and Associate Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medical College (WCMC)/NewYork-Presbyterian Hospital, where she serves as an Associate Professor of Neuroscience in Neurology and Radiology. She is also an adjunct faculty member at the Department of Psychiatry at New York University (NYU) School of Medicine, and at the Department of Nutrition at NYU Steinhardt School of Nutrition and Public Health. Dr. Mosconi holds a PhD degree in Neuroscience and Nuclear Medicine, and is a certified Integrative Nutritionist and holistic healthcare practitioner. Her expertise lies in examining the way gender impacts the health of the brain and body, and in overcoming the massive gender gap in the world of medicine. As she describes in her amazing book, The XX Brain, since the time of Darwin there was a long-held assumption that women’s brains are inferior because they are smaller, but women are generally smaller than men, which was not taken into account for decades, and still persists subconsciously in many areas of medicine and neuroscience. Podcast Time Stamps 3:10 Why Lisa wanted to be a scientist and study the human mind and brain 9:22 Why Alzheimer’s is not just a result of genetic mutations and old age 12:12 The difference between early onset and late onset dementia 14:56 Why you should be careful of taking genetic tests like 23 & me 21:26 Why most research is done on men and the disaster at the heart of medicine 32:54 The communication between the female brain and the female reproductive system, and why our hormones are crucial for brain health 40:11 The brain in middle-aged women, and how menopause can contribute to cognitive decline 47:25 How you as a woman can take back your health and prevent memory loss! 59:00 How chronic stress impacts our hormones and brain health 1:07:25 The power of the X gene, and why women have more genes than men For more info on Dr. Lisa Mosconi and to get her book visit: https://www.lisamosconi.com Read the show blog and transcript here: https://drleaf.com/blogs/news/why-is-depression-anxiety-and-alzheimer-s-more-common-in-women-how-to-protect-women-s-brains-from-aging-and-disease-with-dr-lisa-mosconi This podcast was made possible by our sponsor ThirdLove: Comfortable bras are so hard to find, which is why I am a big fan of ThirdLove! They are a company dedicated to helping women around the world look great and feel confident in their bodies, and have donated over $18 million worth of bras to women around the world! To get 15% off your ThirdLove order see: thirdlove/drleaf Additional Resources: -Join my text group for more tips, notifications of sales, and more! Just text DRLEAF to 80519 -Get my new brain detox app SWITCH on sale now! Get 50% off a 3 month subscription. Just look for Switch on Your Brain in the App Store or Google Play or visit: https://theswitch.app -Get any of my books, DVDs, and workbooks for less 25% with code DRLEAF at checkout: https://drleaf.com/collections/all -Register now for my 2020 Mental Health Summit Dec 3-5 in Dallas, TX! Early bird sale ends 5/30: https://www.drleafconference.com Visit my website at https://drleaf.com for more free resources, tips, and tools to help you improve and heal your mental health! And be sure to sign up for my weekly newsletter to get even more mental self-care tips delivered to your inbox weekly and to see my upcoming events (you can sign up at drleaf.com!) Follow me on social media for daily mental self-care tips! -Instagram: @drcarolineleaf: https://www.instagram.com/drcarolineleaf/ -Facebook: Dr. Caroline Leaf: https://www.facebook.com/drleaf -Twitter: @drcarolineleaf: https://twitter.com/DrCarolineLeaf -Youtube: https://www.youtube.com/drcarolineleaf If you enjoyed this episode please leave a 5 review on iTunes, Google Play, or wherever you are listening! And don't forget to subscribe and share this podcast with friends and family! I love seeing your posts on social media! For podcast sponsorship inquiries, questions regarding the episode, or topic suggestions please email dominique@drleaf.com
Lisa Mosconi, PhD, is a neuroscientist and author of The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease. She is the Director of the Women’s Brain Initiative and Associate Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medical College (WCMC)/NewYork-Presbyterian Hospital, where she serves as an Associate Professor of Neuroscience in Neurology and Radiology. She is also an adjunct faculty member at the Department of Psychiatry at New York University (NYU) School of Medicine, and t the Department of Nutrition at NYU Steinhardt School of Nutrition and Public Health.
I lost my grandmother to Alzheimer’s disease and it was a completely devastating experience to endure. Once I learned there were preventative measures that could be taken, I knew I had to educate myself further...for me, my family and you! I was introduced to Dr. Lisa Mosconi, an incredibly admirable woman working hard on Alzheimer’s research. She is the Director of the Women’s Brain Initiative and Associate Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medical College, where she serves as an Associate Professor of Neuroscience in Neurology and Radiology. She is the author of the new book, The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer’s Disease. Visit Amazon to get a copy of The XX Brain! For information about the female brain visit www.nih.gov and www.menopause.org Visit www.littlejamesclothing.com and use code WithWhit20 for 20% off Buy your Bombas at bombas.com/withwhit TODAY, and get twenty percent off your first purchase. Produced by Dear Media.
My guest today is a neuroscientist and neuro-nutritionist recognized and respected for her contributions to the fields of brain science, the microbiome, and nutritional genomics. Dr. Lisa Mosconi is the founder and director of the Women's Brain Initiative and associate director of the Alzheimer's Prevention Clinic at Weill Cornell Medical College in New York. She’s also an associate professor of neuroscience in neurology and radiology at Weill Cornell and an adjunct faculty member at New York University’s Department of Psychiatry.Her current scientific work focuses on the early detection of Alzheimer’s disease in at-risk people, particularly women. More than a decade of research has shown two things, Dr. Mosconi says: “No. 1, Alzheimer's Disease is not a disease of old age, but rather the disease starts with negative changes in the brain years—if not decades—before any clinical symptoms emerge. So, we're looking at midlife, rather than when you're 70 or 80. No. 2, women tend to develop these negative changes in their brains before men do, and specifically as women go through menopause. That was a big finding.”“Menopause symptoms don't start in the ovaries,” she says, “they start in the brain.” That’s why Dr. Mosconi uses brain imaging techniques such as positron emission tomography (PET) and magnetic resonance imaging (MRI). She is passionately interested in how risk of memory loss and Alzheimer’s disease can be mitigated, if not prevented, through the combination of appropriate medical care and lifestyle modifications involving diet, nutrition, physical and intellectual fitness. She details this in her new book, “The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease.”Dr. Mosconi’s research into women’s neurological health is changing the way science approaches the female brain. Enjoy the show! … And get more resources at Dave.Asprey/podcasts.
As our listeners know I get particularly excited about having certain guests on this show. This episode is one of those guests! I have been after Dr Richard Isaacson for over a year now and I had to make a special trip to NYC to go bang on his door to get his attention here...but the reason I am so excited is because the kind of work that Richard is doing is truly pioneering in the Alzheimer's community and his recently published paper. We'll talk about this in great detail, but by way of introduction. Dr Richard Isaacson finished both his undergraduate degree as well as medical school in just 6 years. Completed his neurology residency at Beth Israel Deaconess/Harvard Medical School and now serves as the Director of the Alzheimer’s Prevention Clinic at Weill Cornell in New York City. Finally, and perhaps most important, he and his wife just welcomed their first child into this world....congratulations and Welcome to the show, Dr Isaacson! This is a great episode where we discuss a first-of-its-kind (prospective design) paper showing that early interventions work to prevent Alzheimer's and treat early symptoms. An episode not to be missed. A deep discussion of the research and some of the controversies surrounding Alzheimer's research.
Richard Isaacson is a board-certified neurologist and director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and New York-Presbyterian.
Podcast Notes Key Takeaways Alzheimer’s disease starts in the brain 20 to 30 years before the first symptoms of memory lossOn ApoE:ApoE is a geneThere are four different isoforms (aka alleles) of ApoEThey’re referred to as 1, 2, 3, and 4 (but most of the time you’ll find 2, 3 and 4)Everybody has two copies of the ApoE gene (one from mom and one from dad)Most people have two copies of ApoE3People with an ApoE4 allele have an increased risk of Alzheimer’s disease (you can use 23andMe to see your ApoE phenotype)People with one allele have a 2-3 fold higher risk of Alzheimer’s disease, while those two alleles have a 10-15 fold higher risk Alzheimer’s disease risk reduction techniques:Physical activity is SUPER important “Exercise is by far the best thing a person can do to protect against Alzheimer’s disease… Physical exercise is by far the most powerful antidote to ApoE that I know of.” – Richard IsaacsonEat fatty fish (wild salmon, sardines, mackerel, lake trout, and herring) for optimal omega-3 fatty acid consumptionGet adequate sleepMonitor your body fat: “As the belly size gets larger, the memory center in the brain gets smaller” – Richard IsaacsonIf someone with mild cognitive impairment (AKA Stage II Alzheimer’s disease) follows a tailored set of recommendations and risk reduction techniques, it’s possible to delay conversion to dementia (AKA Stage III Alzheimer’s disease)Read the full notes @ podcastnotes.orgRichard Isaacson is a board-certified neurologist and director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and New York-Presbyterian.
Podcast Notes Key Takeaways Alzheimer’s disease starts in the brain 20 to 30 years before the first symptoms of memory lossOn ApoE:ApoE is a geneThere are four different isoforms (aka alleles) of ApoEThey’re referred to as 1, 2, 3, and 4 (but most of the time you’ll find 2, 3 and 4)Everybody has two copies of the ApoE gene (one from mom and one from dad)Most people have two copies of ApoE3People with an ApoE4 allele have an increased risk of Alzheimer’s disease (you can use 23andMe to see your ApoE phenotype)People with one allele have a 2-3 fold higher risk of Alzheimer’s disease, while those two alleles have a 10-15 fold higher risk Alzheimer’s disease risk reduction techniques:Physical activity is SUPER important “Exercise is by far the best thing a person can do to protect against Alzheimer’s disease… Physical exercise is by far the most powerful antidote to ApoE that I know of.” – Richard IsaacsonEat fatty fish (wild salmon, sardines, mackerel, lake trout, and herring) for optimal omega-3 fatty acid consumptionGet adequate sleepMonitor your body fat: “As the belly size gets larger, the memory center in the brain gets smaller” – Richard IsaacsonIf someone with mild cognitive impairment (AKA Stage II Alzheimer’s disease) follows a tailored set of recommendations and risk reduction techniques, it’s possible to delay conversion to dementia (AKA Stage III Alzheimer’s disease)Read the full notes @ podcastnotes.orgRichard Isaacson is a board-certified neurologist and director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and New York-Presbyterian.
Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medical College Dr. Richard Isaacson talks about why he began studying Alzheimer's (4:07), how it starts 20-30 years before symptoms appear (4:38), how many people have it and the early signs of it (6:06), the three stages of the disease (8:27), ABC's of Alzheimer's prevention management (10:51), the reason for the study (17:21) and why they wanted to look at sleep (18:19), the value of cost-effective, non-invasive monitoring (19:49), the study's hypothesis and methodology (23:10), conclusions based on the WHOOP data (29:56), implications for future research (34:29), his own personal learnings from wearing WHOOP (38:52), and tips for what we can all do to prevent Alzheimer's (43:05). Support the show (http://whoop.com)
Dr. Richard Isaacson, Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine, shares the just-published results of his groundbreaking clinical trial which show that a personalized prevention plan can dramatically lower the risk or progression of Alzheimer's. Also joining the discussion is one of Dr. Isaacson’s patients who is living proof that this new approach works.
Some 46 million Americans already have the early brain changes that are the harbingers of a dementia that won’t reveal itself for decades. Dr. Richard Isaacson, Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine, talks about the three stages of cognitive impairment, how to distinguish “senior moments” from symptoms of dementia, and whether multitasking puts our overloaded brains at risk.
Today’s interview is with Lisa Mosconi, PhD. She is the associate director of the Alzheimer’s Prevention Clinic at Weil Cornell Medical College in New York. Prior to that she served as the director of the Nutrition and Brain Fitness Lab at New York University, School of Medicine. Dr. Mosconi holds a dual PhD degree in neuroscience as well as nuclear medicine from the University of Florence, Italy, and is board-certified in integrative nutrition. I think will really enjoy this interview and learn about her new book, Brain Food, which not only looks at nutrition but also leverages the science of nutritional genomics, and even the emerging science relating to the role of the microbiome in brain health. The book provides recommendations that we can all use with respect to the foods we eat and, interestingly, she does challenge some of our long-held notions. I hope you enjoy this discussion.
Three doctors/researchers you should know about in the field of DementiaDr. Dale Bredesen wrote “The End of Alzheimers” Professor of Neurology Easton Laboratories for Neurodegenerative Disease Research David Geffen School of Medicine at UCLA Richard Isaacson, M.D: Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and New York-Presbyterian Amy Berger who wrote the “Alzheimer's Andidote” ------------------------------------------------------------ Alzheimer's is the most common neurodegenerative disorder. Responsible for 60-80 percent of all dementia (cognitive decline) There may be a predisposition (genetic component) if you carry ApoE-4. This gene increases risk 5-15% A common one amyloid plaques (for the docs) or tau proteins. They are a mediator likely NOT the cause We need to stop thinking of amyloid as a target There are also subtypes (a mix but what is predominant) Inflammatory : assoc with overactive immune system Constantly be fighting somethin Chronic infection, leaky gut etc.. Atrophic : lacks proper signaling to promote synapse preservation Missing necessary signaling molecules or support. E.g not enough hormones (estradiol/testosterone thyroid), vitamin D, BDNF etc. The brain “downsizes” because you cannot support the neural network you have Many people have both inflammatory and atrophic. These first two are more common with APOE4 "Type 1.5": glycolic damage (insulin resistance of the brain) Toxic (possibly earlier onset) Less common BUT many times if type 1 or 2, likely a bit of contributing toxic type Fungal (molds), viral, bacterial, chemical Often APOE4 negative individuals / younger / women Trouble with executive function like calculating a tip / bills etc. Often have low Triglycerides/low zinc/high copper. Not sure what this means PPIs decrease absorption of zinc, copper pipes too Even if you have the gene, if you identify this early enough, we can institute changes in our lifestyle to delay or avoid onset. What does Dr. Breseden suggest: Look at toxin burden (molds/skincare/food/food containers etc) Wash after (mercury/BPA) etc comes out in sweat mycometrics.com Remove from environment PLUS sauna EPA relative mold index (want less then 2) 12-16 hours of daily fasting starting 3 hours before bed If APOE 4 (closer to 16) Reduce inflammation Low carb/sleep/stress Removing food intolerance Heal leaky gut (inflammation is how gut is so connected to brain) Mild Ketosis (his program is called Ketoflex) You many be able to stop supplementing Unless you lose too much weight If lose weight 1-2 days of adding carbs Fish works, supplements don't Avoid fish high in mercury like tuna Stick to salmon, mackerel, sardines 70% of calories from fat, low carb Plus fasting If your starting from high carb - start with MCTS → omega 3/polyuns Once you can make ketones on your own (fat adapted) ITS NOT ABOUT ONE THING and its about changing the signaling and providing the appropriate tools (omega 3), decreasing toxins or getting rid of toxins
In this episode, Richard Isaacson, a neurologist and director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and NewYork-Presbyterian, discusses strategies for staving off Alzheimer’s disease. Richard shares a wealth of insight for people who want to know more about Alzheimer’s and what you can do to help yourself and your loved ones – starting today and continuing throughout the entire lifespan. We discuss: Richard’s fun-facts (and alter egos): “bling” phones, Doogie Howser, and DJ Rush [8:00]; Richard’s impetus to focus on Alzheimer’s disease: Uncle Bob [18:20]; Starting an Alzheimer’s Prevention Clinic [27:00]; How Alzheimer’s is diagnosed [30:00]; Short-term memory, processing speed, executive function and how they’re tested [35:45]; Prevention vs reduction of Alzheimer’s [44:00]; What is the prevalence of Alzheimer’s in America? [49:30]; How do people actually die from Alzheimer’s or dementia? [51:30]; How can people do everything right and still get Alzheimer’s? It’s all about AGE [55:15]; The APOE gene [58:15]; Why is the risk of Alzheimer’s higher for women? [1:13:00]; How many different paths lead to Alzheimer’s? [1:15:45]; What role does MTHFR play in Alzheimer’s? [1:19:45]; What are the “ABCs” of Alzheimer’s prevention? [1:26:45]; Baptists, Tauists, Syners, and Apostates [1:36:30]; Concerns with statin use for high-risk patients [1:45:00]; The use of Theracurmin [1:48:45]; What are the five actionable things one can do to reduce the risk for Alzheimer’s today? [1:54:30]; The cognitive reserve [2:14:15]; and More. Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.
Most health and diet books focus on reducing your waistline but neglect the most "mission critical" part of your entire body: your brain. The 3 lbs, watery, fatty mass between your ears needs to be fed well and cared for, but most people don't give brain health the attention it deserves. Meet Dr. Lisa Mosconi, neuroscientist and author, and learn how your brain health can be dramatically influenced by food and lifestyle. ------------ Listen & Learn: Why your body can survive on many foods, but your brain is much more picky The importance of essential fatty acids for brain health Why the brain's saturated fat and cholesterol is created by the brain and stored in the brain from childhood—not affected by diet Why too much Omega-6 from seed oils is a problem for inflammation Why a 2:1 ratio of omega-6 to omega-3 is ideal (while most people get 20+:1) Why we need around 4 grams of omega-3's per day Why the brain needs glucose for neuron synthesis and balance Why alcohol enters the brain and dehydrates your brain ABOUT OUR GUEST Dr. Mosconi holds a PhD degree in Neuroscience and Nuclear Medicine, and is a certified Integrative Nutritionist and holistic healthcare practitioner. She is the Associate Director of the Alzheimer's Prevention Clinic at Weill Cornell Medical College (WCMC)/NewYork-Presbyterian Hospital, She is an adjunct faculty member at NYU and the University of Florence. Dr. Mosconi has published over 100 peer-reviewed papers in medical journals. Her new book, Brain Food: the Surprising Science of Eating for Cognitive Power we'll talk about today. Nutritional Tip of the Week: Cinnamon Links & References from the Show: Dr. Mosconi's Website Brain Food Book Got Questions? Send me a voicemail here: Ask Lucas a Question Or write to us: podcast@yogabody.com Like the Show? Leave us a Review on iTunes Thanks to our sponsor: SeatGeek - Buying tickets can be complicated and confusing, but there is a better way to buy – with SeatGeek. SeatGeek is the smartest, easiest way to get tickets to every type of live event. Whether you're searching for a last minute deal, planning a night out with friends, or need to find the perfect gift, SeatGeek helps you find the best seats at the best prices – fully guaranteed. Just download the SeatGeek app and enter promo code ‘YOGA' today. That's promo code ‘YOGA' for $20 off your first SeatGeek purchase. Learn More
This week we’re talking to Dr. Lisa Mosconi. Lisa is the Associate Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medical College (WCMC)/NewYork-Presbyterian Hospital. Before that she founded and was the director of the Nutrition & Brain Fitness Lab at New York University School of Medicine (NYU). Lisa holds a PhD degree in Neuroscience & […]
In Part 1 of our conversation with neuroscientist Dr. Lisa Mosconi, we learned more about the connection between estrogen, menopause, and Alzheimer's. In short, in perimenopause and menopause, as estrogen declines, women lose some of the neuroprotective advantages of the hormone, making them more vulnerable to Alzheimer's disease. Make sure to listen to Part 1 to get grounded in the science. In Part 2, Dr. Mosconi lets us in on how we can protect our brains from the cognitive decline of Alzheimer's. Food, exercise, intellectual stimulation all have a part to play, so you're going to want to hear what Dr. Mosconi has to say. (Bonus: a lot of these same tips can help men age better, too.) Learn more about Dr. Mosconi, the Alzheimer’s Prevention Clinic, and how you might participate in their research. If you want to start nourishing your brain against age-related decline (“eating for retirement,” as Dr. Mosconi puts it), get your hands on a copy of her fascinating and very readable book, Brain Food: the Surprising Science of Eating for Cognitive Power. See the full transcript of our conversation on genneve.com, then join the conversation in our community forums!
“In the next three minutes, 3 people will develop Alzheimer’s. Two of them will be women.” As neuroscientist Dr. Lisa Mosconi says in her article, “Alzheimer’s and Women’s Health, an Urgent Call,” while women account for two-thirds of Alzheimer’s cases, little is being done to understand why simply being a woman significantly increases your risk of developing the disease. Dr. Mosconi is Associate Director of the Weill Cornell Alzheimer’s Prevention Clinic, where she and her colleagues are working to understand this critical – and critically overlooked – piece of women’s healthcare. Team genneve came across this story because Dr. Mosconi and others have linked Alzheimer’s disease with menopause. They postulate that as estrogen levels subside in a woman’s body as she ages, so do its neurological protections. As Dr. Mosconi puts it: “In straight talk: menopause causes metabolic changes in the brain that seem to increase the risk of Alzheimer’s disease.” “In straight talk: menopause causes metabolic changes in the brain that seem to increase the risk of Alzheimer’s disease.” Fortunately, as Dr. Mosconi has helped identify the problem, she has also helped point to some powerful solutions. Exercise and nutrition, she says, can play a significant role in preventing cognitive decline. In Part 1 of her podcast with genneve CEO Jill Angelo, Dr. Mosconi explains the mechanism behind menopause and Alzheimer’s risk. Come back for Part 2, where she discusses how women can protect their brains as they age. Learn more about Dr. Mosconi, the Alzheimer’s Prevention Clinic, and how you might participate in their research. If you want to start nourishing your brain (“eating for retirement,” as Dr. Mosconi puts it), get your hands on a copy of her fascinating and very readable book, Brain Food: the Surprising Science of Eating for Cognitive Power. For a full transcript of this conversation, join us at genneve.com. For further reading on nutrition and your health: check out how your gut flora affects your brain power and, now that you’re going to eat so much better, how to give up sugar.
David is joined by Dr. Lisa Mosconi, the Associate Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medical College/New York-Presbyterian Hospital and author of the upcoming book Brain Food: The Surprising Science of Eating for Cognitive Power. Get in on the conversation as David and Dr. Lisa discuss how what we eat can affect the brain and changes we can make to improve our lives.
Dr. Adam Kaufman, OrthoTrauma surgeon at Mission Health, discusses the fracture prevention clinic and the impact of osteoporosis on the elderly.
Dr. Richard Isaacson founded the Alzheimer’s Prevention Clinic at the NewYork-Presbyterian/Weill Cornell Medical Center, where he’s leading a study examining Alzheimer’s in women, seeking brain changes that occur long before symptoms do. He is joined by UsAgainstAlzheimer's board member Karen Segal, who is participating in this study.Support the show (https://www.usagainstalzheimers.org/ways-donate)