Podcasts about brca

When faced with a Stage IV terminal cancer diagnosis at age 37, how do you keep living, surfing big waves, and raising a child?In this powerful episode, author and big-wave surfer Melanie Ezell joins Leah to share her unfiltered story of surviving Stage IV ovarian cancer, navigating recurrences, and finding profound joy despite an incurable diagnosis.Melanie, author of the memoir Inherited: A Life Without a Cure and writer behind the popular Substack An Incurable Life, opens up about using big-wave surfing to mirror her mental health, taking ownership of her healing, and building a life fully lived alongside mortality.In this episode:Surfing as a Mirror: Melanie's journey from Michigan to riding big waves in Hawaii and Mexico—and how the ocean reflects her inner emotional state.The Diagnosis: Her BRCA1 genetic mutation background, subtle ovarian cancer symptoms, and receiving a Stage IV diagnosis in 2022.Integrative & Alternative Cancer Care: Navigating ketogenic and Gerson diets, fasting, supplements, Dr. Joe Dispenza meditation, and plant medicine (Ayahuasca and Psilocybin) in search of the “root” cause of her cancer.Addressing Emotional Roots: How tackling codependency, resentment, setting firm boundaries, and writing her memoir became crucial parts of her healing journey.(Note: Brief mention of past eating disorders).Subscribe to Melanie on Substack: https://substack.com/@melanieezellVisit her website http://www.melanieezell.comFollow her on Instagram @yogasurfmeland Facebook https://www.facebook.com/melanie.malskiBuy her book, Inherited: A Life Without a CureLeave a message with your thoughts about the episode!Support the showBecome a member of The Cancer Pod Community! Support the podcast and gain access to exclusive content and more! Join today on Buy Me a Coffee or Patreon.Check out thecancerpod.com! Looking for more information? The website has blogs, merch, and all of the episodes listed by season and category. Shop the Bookshop! The shelves at Bookshop feature books by authors who have been on the show and other fav books.Buy The Cancer Pod merch! Whether it's a cozy hoody or a handy water bottle, we have something for everybody.Have a comment or suggestion? Email info (at) thecancerpod (dot) com Follow @TheCancerPod on social media:InstagramBlueskyFacebookLinkedInYouTube

Should I be screened for breast or lung cancer, and what should I expect? Meghana Raghavendra, MD, Board-certified medical oncologist and hematologist practicing at Franciscan Health, walks through the Pink and Pearl awareness campaign and practical screening guidance. She cites that nearly one in eight women will be diagnosed with breast cancer and about one in 17 with lung cancer, explains mammogram recommendations (start at 40, annual, continue through ~74; add MRI/ultrasound for high risk), and details LDCT lung screening (age 50–80, 20 pack‑year history, current smokers or quit within 15 years, with Franciscan offering screening beyond that time cap). She reviews key risk factors—BRCA and family history, dense breasts, prior chest radiation, smoking, second‑hand and occupational exposures—and reminders that mammograms can detect changes up to two years before a lump is palpable. The episode also covers patient concerns about stigma, why screening is quick and painless, and prevention steps like quitting smoking, limiting alcohol, exercising, testing homes for radon, and advocating for any breast or lung symptoms with your provider.  Learn more about Dr. Raghavendra, visit FranciscanDocs.org and search her name. 

DeSoto Hope Returns: A Night of Hope “Giving Cancer the Boot” + Survivor Stories & How to Get ScreenedHost Derrick Michaud welcomes Tracy Gallagher, Ashleigh Parker, and Tina James from DeSoto Hope to reintroduce the DeSoto County nonprofit's mission to ensure no one feels forgotten during their cancer journey through Hope Baskets, $500 travel grants for second opinions, and $2,500 scholarships for students impacted by cancer. They are promoting the 6th annual “A Night of Hope: Giving Cancer the Boot” on Tuesday, October 27 at the DeSoto County Agri-Education Center (doors 6:00, food 6:30), featuring photo booths, a petting zoo, silent auction, raffles (including a diamond necklace), wine/bourbon pulls, a cash bar, and live music by the Side Street Steppers, with Derrick emceeing. The conversation also covers the guests' cancer experiences, prevention and early detection, genetic testing and BRCA risk, ctDNA tests like Signatera/Guardant, second opinions, and mental health support.TICKETS - https://wedoauctions.com/app/public/bidapp/desotohope/tickets/tickets?fbclid=IwY2xjawUaT6FwZG9mBWV4dG4DYWVtAjEwAGJyaWQRMTJ1bWJQM2Y0N0dSYjNCSk1zcnRjBmFwcF9pZBAyMjIwMzkxNzg4MjAwODkyAAEe3A0AJ7dHnpatbGmBboNQ7cwt9rORuR-uUIGrVIY3-LJIxRZ0ZDKXBAMVMvU_aem_I1tEs_NuEBw7d4EaCc6JkwSponsored in part by Electrical Repair and Installation and Brandon Vanderburg at Shelter InsuranceThe Real Hernando is on YouTube, Apple, Spotify, Facebook, Instagram and TikTokProduced by Derrick Michaud and SRP Studios Podcasting

Featuring perspectives from Dr David W Cescon, including the following topics: Clinical treatment of BRCA-mutated metastatic triple-negative breast cancer (0:00) CNS activity of TROP2-directed antibody-drug conjugates (5:36) Autoimmune considerations with immunotherapy (10:09) Treatment of oligoprogressive advanced breast cancer (17:31) CME information and select publications

In this podcast episode, Hope S. Rugo, MD, FASCO, and Nerea Lopetegui-Lia, MD, discuss practice-informing data presented at ASCO 2026 for patients with metastatic breast cancer, including:Findings from SERENA-6 on ctDNA-guided treatment switching for emergent ESR1 mutations before radiographic progression, including updated PFS2 and downstream treatment outcomesEmerging precision strategies in HR-positive/HER2-negative advanced breast cancer from ELEVATE and PIKALO-1, including elacestrant plus capivasertib and mutant-selective PI3Kα inhibition with tersolisibFirst-line TROP2-directed ADC data from ASCENT-04, ASCENT-03, and TROPION-Breast02, with discussion of PFS2, subsequent therapy, immunotherapy eligibility, and treatment sequencing Presenters: Hope S. Rugo, MD, FASCO Director, Women's Cancer Program Division Chief, Breast Medical Oncology Professor, Department of Medical Oncology & Therapeutics Research City of Hope Comprehensive Cancer Center Professor Emeritus and Emeritus Winterhof Family Distinguished Professor of Breast Oncology University of California, San Francisco San Francisco, California Nerea Lopetegui-Lia, MD Assistant Professor Division of Medical Oncology, Breast Section Department of Internal Medicine The Ohio State University Columbus, Ohio Get access to all of our new podcasts by subscribing to the Decera Clinical Education [Oncology] Podcast on Apple Podcasts, YouTube Music, or Spotify.Link to full program:https://bit.ly/4x4u5AT Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

It's been a long time comin but WE ARE BACK! We missed talking to you guys so much, it feels so good to finally be back.00:38 - Why we left4:00 - Baily's update11:50 - Jade's engagement story & TTC updates21:40 - Secret Lives of Mormon Wives recap & News40:13 - Earle Girls Show thoughts51:13 - Alex Cooper is just as bad as a man?In this episode, we explain where we've been and what we've invested in to never leave you again. Dad's home 4ever, girls! We also get in to our updates since we've been gone. Paige and Baily give updates on if they're single, where they live, and the loss of Paige's dog & former YPD co host, Roman. Jade gives the story of her engagement & updates on wedding plans and her TTC journey.Then, we get into all the good TV that has just come out! We talk about Secret Lives of Mormon wives. Taylor Frankie Paul has turned into a monster and is terrorizing everyone, making the show harder to watch. Mikayla leaves the show and takes a stand against TFP's behavior. Jessi has the biggest crush on Chase who looks just like Tommy Pickles, if he was grown up. Next, we talk about Earle Girls! We discuss the most un-relatable thing about the 2 sisters: they're HUGGING sisters. We also think that it was so amazing that Alix and Ashtin shared their testing for the BRCA gene and think they will help so many people.Finally, we get into the villain of the show: ALEX COOPER. We discuss our thoughts on Alex v. Alix and who we think is in the right. We're SO HAPPY to be back! We miss all of your listener emails; telling us your stories or asking us for advice! Submit your stories and/or advice questions and we will read them on the episode! Email us at yourpoordad@gmail.com or DM us on Instagram at ⁠instagram.com/yourpoordadpod⁠  

Broadcast from KSQD, Santa Cruz on 9-17-2026: Dr. Dawn opens with a primer on kidney function: their embryonic origin adjacent to the gonads, their central role in blood pressure regulation (retaining fluid in hemorrhage but paradoxically worsening heart failure), erythropoietin production (both an athletic doping agent and a mechanism by which severe sleep apnea can cause stroke-risk polycythemia), acid-base balance via bicarbonate, and nitrogen waste removal including uric acid. The U.S. waiting list holds 95,492 people needing kidney transplants—88% of all organ waitlist patients—against only 27,500 annual donations, with 12-13 people dying daily on the list. Dr. Dawn walks through a Wired magazine analysis of paid donation, noting Iran is the only country with a legal regulated kidney market (Iranian citizens only, with a waiting list of donors and compensation around two months of median income). She frames the ethical debate: current U.S. altruistic donation implicitly rewards those with money and social networks who can afford time off, while poorer populations bear disproportionate end-stage renal disease burden. Proposed compensation alternatives include lifetime congressional-quality health insurance, student loan forgiveness, six-month waiting periods for informed consent, and 20-year payout structures. Donation mortality risk is comparable to childbirth—several-fold lower than logging. Tim Andrews became the first patient to receive a genetically modified pig kidney as a bridge to human transplant, sustaining him 271 days until a human kidney became available (the pig kidney ultimately lost to pyelonephritis, not rejection). eGenesis used CRISPR to delete three highly antigenic pig genes—GGTA1 (which produces alpha-gal, the tick-transmitted meat allergy trigger), CMAH, and one other—along with porcine endogenous retroviruses, and added seven human genes for coagulation compatibility and anti-inflammation. Dr. Dawn notes the animal welfare implications of farming 50,000 modified pigs annually and unknown long-term graft survival. An emailer asks about direct-to-consumer full-body MRI screening. Dr. Dawn explains MRI's advantages (no ionizing radiation, no kidney-toxic contrast) but emphasizes false positive harms: indeterminate findings that require invasive follow-up biopsies for lesions unlikely to be lethal, and the psychological burden of "ghost" diagnoses. Whole-body MRI also poorly evaluates lungs, intestines, and breasts (different scan parameters required). She recommends full-body MRI only for high-risk cancer predisposition syndromes like Lynch syndrome, BRCA 1/2, and Li-Fraumeni. Dr. Dawn debunks the "seed" model of probiotic capsules: strains taken for six months typically disappear from the gut within a month of stopping. Much of probiotic benefit comes from dead bacteria—autoclaved cell walls remain biologically active with antibacterial effects. Her clinical protocol uses 200-300 billion CFU four times daily to treat traveler's diarrhea, avoiding Cipro's tendon toxicity. For antibiotic-associated C. difficile prevention, Saccharomyces boulardii plus Bifidobacterium and Lactobacillus have double-blind placebo-controlled support when taken between antibiotic doses and for a week afterward. A caller with type 2 diabetes describes suspected treatment-induced neuropathy following rapid A1c reduction from 10.2 to a GMI of 5.8. She has burning, electric tingling, and unexplained deep muscle-soreness sensations, mostly proximal in the left leg with recent right-leg involvement, and pregabalin isn't helping. Dr. Dawn distinguishes small-fiber neuropathy (temperature-related, patchy, requires skin biopsy for diagnosis—EMG and nerve conduction won't show it) from large-fiber neuropathy (symmetric, ascending from toes). The proximal top-down distribution suggests small-fiber involvement. She recommends functional-medicine adjuncts: methylated B12 2,000 mcg, methylated folate 2,000 mcg, and alpha-lipoic acid 300 mg twice daily for three months. She also recommends a provoked heavy-metals urine test to rule out copper or other neurotoxic exposure. Dr. Dawn closes with the fiber recommendation of 14 grams per 1,000 calories (correcting an earlier misstatement of 14g total per day) and emphasizes that a diverse plant-based diet—fruits, vegetables, root vegetables, beans, nuts—does more for microbiome health than any capsule.

Mentor Sessions Ep 096: Zack Shapiro explains AI existential risk, AI regulation, the Clarity Act, Samurai Wallet, and open source AI policy for Bitcoin.The Clarity Act just failed on the Senate floor, and the fight over whether writing Bitcoin code can be treated as a crime is now heading to 70-year-old federal judges. Zack Shapiro breaks down what that means for self-custody, open source software, and the Samurai Wallet developers still behind bars.In this conversation you'll learn why Zack separates AI existential risk (recursive self-improvement, the orthogonality thesis, instrumental convergence) from the ordinary risks of AI — job displacement, regulatory capture by frontier labs, and cyber attacks like the Cold Card hack. You'll see why he thinks open source AI is not the existential threat, why the Blockchain Regulatory Certainty Act (BRCA) matters more than most Bitcoiners realize, and how the 'two clocks' of AI capability vs enterprise adoption will define the next decade. You'll also get the legal reality behind white hat recovery of hacked Bitcoin, why the liquid hacker is in a bad spot, and what happened when the Clarity Act died on the vine.⏱️ Timestamps:0:00 - Intro0:51 - Amodei, Musk and Altman urge AI slowdown1:38 - Ordinary risks versus existential AI threats2:26 - Politics warping the AI safety debate3:20 - Bostrom, AGI and intelligence explosion risks5:01 - Orthogonality thesis and instrumental convergence5:59 - Hugging Face attack shows AI covering tracks6:58 - No easy policy fixes for AI risks8:08 - Can't stop AI progress or open source China9:32 - Separating x-risk concerns from anti-AI populism12:22 - Regulatory capture and Anthropic IPO timing14:21 - Keeping open source AI legal and available16:39 - Trezor self-custody sponsor read17:43 - One shot parallel between Bitcoin and AI19:37 - Where real AI productivity gains appear20:47 - Two Clocks: capability versus enterprise adoption24:22 - Is AI coming for your job?25:28 - Electrification analogy and 30-year lag28:34 - Jevons Paradox and future of work30:42 - White hat recovery of Cold Card hacked funds34:02 - Legal precedent for white hat bounties36:56 - Why the Liquid hacker faces trouble38:55 - What's actually in the Clarity Act43:46 - Money transmitter law and the Samurai case45:20 - Tornado Cash, FinCEN and frying pan argument47:31 - Why this could ban using Bitcoin49:33 - BRCA criminal protections and court battles53:42 - Clarity Act fails to pass what happened55:24 - Senator Lummis stood on principle56:50 - Where to follow Zack ShapiroGuest: Zack Shapiro — lawyer and AI-native law firm builder covering crypto policy, AI regulation, and Bitcoin legal defense.

Eight bank groups demanded a total stablecoin yield ban hours before today's 2:15pm cloture vote, and the White House called deposit flight a boogeyman. We break down Bessent's kill switch, the BRCA carve-out that got gutted, and why banks have been running the same script since 1980.~This episode is sponsored by iTrust Capital~iTrustCapital | Get $100 Funding Reward + No Monthly Fees when you sign up using our custom link! ➜ https://bit.ly/iTrustPaul00:00 intro00:08 Sponsor: iTrust Capital00:44 CLARITY offer rejected?01:55 CLARITY odds collapse again02:34 Patrick Witt: Dems got everything they wanted with ethics deal03:22 Ethics drama is fake03:56 Banks target republicans to ban yields05:24 Coinbase defends stablecoin yields on Fox News06:23 Bank lobby is powerful06:56 Patrick Witt: Banks are full of shit08:48 White House launches page to convince republicans09:49 Banks should be worried if it doesn't pass10:38 Scott Bessent wants stablecoin adoption11:10 Banks using ancient talking points12:15 Hunter Biden saved CLARITY?12:36 Hunter claiming credit for CLARITY?14:31 Memecoins vs Politics15:35 PLOT TWIST: Mitch Mcconnell is alive16:10 Every vote counts16:46 Senate calendar17:25 Circle & Coinbase stocks fall18:13 Proof Circle will pump if it passes19:05 outro#crypto #bitcoin #Ethereum~CLARITY Vote FINAL HOUR!

GPs Rebecca and Sarah are joined by consultant urologist at Salford Royal and former Director of Urology for the Greater Manchester Cancer Alliance, Mr Sotonye Tolofari to unpack the complexities of prostate cancer screening, PSA testing, and referral pathways in primary care. This episode covers risk factors—including family history, BRCA variants, Black ethnicity, and age—alongside in-depth discussion on when to offer PSA and DRE, the implications of screening, and the latest updates on targeted programmes. The hosts and guest also address patient counselling, overdiagnosis, and the evolving landscape of evidence and policy around early prostate cancer detection.Recommended cancer key articles:When should primary care be concerned about a family history of prostate cancer?A proactive approach to reducing men's cancer risk and mortality If you loved this episode and would like to hear more like this, please send your review to the-christie.gatewayc@nhs.net and share the series with a colleague.GPs Talk Cancer is the podcast series from GatewayC. GatewayC is the free early cancer diagnosis resource funded by the NHS and is part of The Christie NHS Foundation Trust. View the full shownotes for this episode at Podcast - GatewayCProduced by GatewayC and Listening Dog Media.DISCLAIMER: We know this podcast might be of interest to anybody, however it is aimed at primary care health professionals. All patient cases are based on real stories from our clinical practice as GPs. They are fully anonymised with no identifiable patient data. All featured statistics are accurate at the time of recording. All views expressed by guest speakers are their own. Hosted on Acast. See acast.com/privacy for more information.

In this episode of the DiepCJourney® podcast, Terri sits down with Dr. James Craigie of The Center for Natural Breast Reconstruction for an important and compassionate conversation about risk‑reducing mastectomy, genetic mutations, and the reconstructive options available to those navigating increased breast cancer risk. Dr. Craigie brings years of microsurgical expertise and a deeply patient‑centered approach to help listeners understand when and why risk‑reducing surgery may be considered, what the process looks like, and how women can make informed decisions that support long‑term survivorship. Episode Highlights • What BRCA Genetic Mutations Mean for Risk Dr. Craigie explains what the BRCA1 and BRCA2 genetic mutations are, how they increase lifetime breast cancer risk, and why individuals who test positive may choose to explore risk‑reducing mastectomy with reconstruction as a proactive option. • When There's No BRCA Mutation but Family Risk Is High Not everyone with elevated breast cancer risk carries a BRCA mutation. Dr. Craigie discusses how strong family history can still warrant enhanced surveillance or consideration of prophylactic surgery, depending on individual circumstances. • Recommended Screening Before Surgery For those considering risk‑reducing mastectomy, Dr. Craigie outlines the surveillance tools typically recommended beforehand, including mammography, MRI, and clinical breast exams, to ensure comprehensive monitoring during the decision‑making process. • Other Genetic Mutations That Increase Risk Beyond BRCA, Dr. Craigie touches on additional genetic mutations associated with higher breast cancer risk and how they factor into decisions about prophylactic mastectomy and reconstruction. • Steps to Begin the Risk‑Reducing Surgery Journey Dr. Craigie walks listeners through the consultation process, including what to expect, how to prepare, and the importance of meeting with a reconstructive surgeon early to understand all available options. • Common Fears and Concerns About DIEP Flap Reconstruction From recovery time to surgical complexity, Dr. Craigie shares the most frequent concerns patients bring to their consults when exploring prophylactic DIEP flap or other reconstruction methods and how these fears can be addressed with education and support. • How Much Risk Is Reduced After Prophylactic Surgery Dr. Craigie explains the percentage of breast cancer risk reduction achieved through prophylactic mastectomy and why this option can be life‑changing for individuals with significantly elevated risk. Why This Conversation Matters Risk‑reducing mastectomy is a deeply personal decision. This episode offers clarity, compassion, and credible information for anyone navigating genetic risk, family history, or the emotional weight of preventive surgery. Dr. Craigie's insights help empower listeners to make choices aligned with their values, health needs, and long‑term survivorship goals. Listen, Learn, and Share If you or someone you love is exploring genetic testing, elevated breast cancer risk, or reconstruction options, this episode is a powerful resource. Share it with your community because at DiepCFoundation we belive education can help saves lives. Connect with Dr. Cragie and his practice. Instagram: https://www.instagram.com/natural.breast.reconstruction/ Facebook: https://www.facebook.com/naturalbreastreconstruction LinkedIn: https://www.linkedin.com/company/the-center-for-natural-breast-reconstruction/posts/?feedView=all

Welcome to Grid Talk, this week we are talking to Ben Smith, Schumacher team driver who is the newly crowned 2WD and 4WD UK national champion for 2026.We chat to him about his year to doing the double, his work at Schmacher HQ and other racing exploits in this fun filled episode.All that and more on this weeks show#CMLdistribution#SchumacherRacing#Willspeed#GTRC

In 2002, I was assigned a story for Seventeen Magazine about the popularity of the Christian rock scene. They sent me to New Hampshire to attend the Inside Out Soul Festival. The photographer assigned to the story was a young woman named Elizabeth Lippman. Along with her photography assistant, we drove from NYC to Loon Mountain in New Hampshire for a very intense few days where we interviewed a ton of young attendees along with a ton of music acts including a young Katy Perry who at that time performed as Katy Hudson. Elizabeth and I lost touch but I'd see her name from time to time—she went on to shoot a regular column for the New York Times. A few years ago we reconnected. She was now living in LA. I demanded she come on the show so we could properly catch up! We discussed press plates, her experience photographing Trump and other celebrities, being an early Atkins adopter, the Nicki Hilton kerfuffle, growing up the daughter of journalist parents (she was born in Cairo), moving to LA, the difference between directing and photography, learning she was BRCA positive, parenthood, being a reluctant stage mom and so much more. Plus we did a round of JMOE, HGFY and our new words segment. Get yourself some new ARIYNBF merch here: https://alison-rosen-shop.fourthwall.com/ Subscribe to my Substack: http://alisonrosen.substack.com Podcast Palz Product Picks: https://www.amazon.com/shop/alisonrosen/list/2CS1QRYTRP6ER?ref_=cm_sw_r_cp_ud_aipsflist_aipsfalisonrosen_0K0AJFYP84PF1Z61QW2H Products I Use/Recommend/Love: http://amazon.com/shop/alisonrosen Check us out on Patreon: http://patreon.com/alisonrosen   This episode is brought to you by QUINCE! Quince.com/alisonrosen Buy Alison's Fifth Anniversary Edition Book (with new material): Tropical Attire Encouraged (and Other Phrases That Scare Me) https://amzn.to/2JuOqcd You probably need to buy the HGFY ringtone! https://www.alisonrosen.com/store/ Try Amazon Prime Free 30 Day Trial

Personalized wellness is reshaping the entire health conversation, and this new The Next Frontier Files episode proves the old rulebook is officially closed for good. From psychedelics and genetic testing to women's health investment and metabolic health, expert guests from year three of Salad with a Side of Fries reveal the trends that would become some of the biggest wellness breakthroughs, long before the headlines ever catch up.Host Jenn Trepeck shares the ideas from year three of Salad with a Side of Fries, revisiting the boldest predictions, the holistic health conversations, and the recurring threads that shaped where wellness was headed next.What You Will Learn in This Episode:✅ Why the future of health is built on personalized nutrition and genetics rather than one-size-fits-all rules✅ How psychedelics and microdosing are entering the mainstream conversation around consciousness and healing✅ Why metabolic health is being named as the true root cause behind most chronic disease✅ How accessible wellness and honest food conversations are becoming the next big shift in the industryThe Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into real-life wellness and weight loss, including drinking, eating out, and skipping the grocery store.TIMESTAMPS:00:00 A preview of year three, covering psychedelics, genetics, women's health, and personalized wellness03:59 Alexander Carter suggests looking at the individual and questions following the wellness rules05:03 Daniel Sanders and Peter Reitano discuss psychedelics, consciousness, and life extension research07:17 A raw, unscripted mental health conversation shows instead of tells during Awareness Month08:32 Dr. Lisa Oldson connects genetic testing and artificial intelligence to future personalized nutrition09:57 David Frost on gene editing, BRCA, and the ethics of enhancement technology11:20 Sophia DeSantis shares her fertility story and why alternative medicine and modern care can coexist12:23 Marie Van Blerkom exposes the shocking lack of female health companies on the stock exchange13:42 Erica Stein and Aly French challenge food inequality and call for truly accessible wellness15:35 Guests discuss trauma, anti-aging, longevity and aging well17:34 Hope Pedraza links gut health work to spirituality, human design, and total wellness18:28 Dr. Mariza Snyder names metabolic health as the real root cause behind most chronic disease19:54 Justine Ang Fonte hopes the next wellness frontier is genuine body affirmation over profit-driven trends20:20 Jenn ties up her thoughts on year threeKEY TAKEAWAYS:

Today, we are taking a deep dive into a medical truth thatsounds completely counterintuitive, almost upside down, based on everything you think you know about women's health. But here's the kicker: it's actually nothing new at all. For over two decades, ever since the landmark Women'sHealth Initiative (WHI) study made global headlines back in 2002, the blanket narrative surrounding menopausal hormone therapy has been clear and persistent: hormones equal breast cancer risk. But there is a massive asterisk in thatscience that got completely lost in the media noise. While combination therapy with conjugated equine estrogens paired with medroxyprogesterone acetate (CEE +MPA) did show an increased risk, the story for estrogen-only therapy (mainly CEE) in women wh had a hysterectomy is entirely different. In fact, an overwhelming mountain of growing data shows that estrogen-only therapy is protectiveagainst both breast cancer incidence and breast cancer mortality. In this episode, we're unpacking the latest high-level evidence that cements this crucial distinction. We'll examine the broad statistical landscape, including a comprehensive meta-analysis by Qing et al. (officially set for the December 2026 issue of Annals of Medicine, following its ahead-of-print release in March 2026). Their work breaks down how randomized controlled trial data consistentlypoint to estrogen-only therapy having a protective effect, in stark contrast to combination therapy. We'll also dive into a brand-new Clinical Perspective published in mid-August 2026 in Obstetrics & Gynecology (the Green Journal) by Drs. Andrew Kaunitz and Jason Wright. They call urgent attention to this phenomenon, highlighting RCT meta-analyses that demonstrate a 23% reduction in breast cancer incidence with estrogen alone (RR = 0.77), alongside striking cohort data showing a dramatic risk reduction even in high-risk populations, like carriers of the BRCA mutation.  Listenin for details.1.     Wu Q, Shen L, Hu S, Yang R, Wang Y, Xue D, SunY, Ma H, Dai Z. Relationship between menopausal hormone therapy and incidencerisk of breast cancer: systematic review and meta-analysis. Ann Med. 2026Dec;58(1):2640244. doi: 10.1080/07853890.2026.2640244. Epub 2026 Mar.2.     Kaunitz, Wright. Menopausal Estrogen Therapy andRisk of Breast Cancer. Obstet Gynecol. Aug 20263.     Chlebowski RT, Aragaki AK, Pan K, et al.Randomized Trials of Estrogen-Alone and Breast Cancer Incidence: AMeta-Analysis. Breast Cancer Research and Treatment. 2024. 4.     Writing Group for the Women's Health InitiativeInvestigators. (2002). Risks and benefits of estrogen plus progestin in healthypostmenopausal women: Principal results from the Women's Health Initiativerandomized controlled trial. JAMA, 288(3), 321–333.

This episode is sponsored by Gilead Sciences. Gilead had no involvement or input in the podcast content. Gilead is working to transform how cancer is treated. We are innovating with next-generation therapies, combinations, and technologies to deliver improved outcomes for people with cancer. From antibody drug conjugates and small molecules to cell therapy-based approaches, our portfolio and pipeline assets are creating new possibilities for people with cancer.Dr. Sara Tolaney, Chief of the Division of Breast Oncology at Dana-Farber Cancer Institute, returns to Patient From Hell to explain the ASCENT-04/KEYNOTE-D19 study, the phase 3 trial she led as principal investigator, and what it changes for people living with metastatic triple-negative breast cancer.For years, the most effective drugs for metastatic TNBC were only available after first-line chemotherapy had already failed. The problem, as Dr. Tolaney puts it plainly, is that many patients never reach a second line of treatment at all. ASCENT-04 asked whether moving an antibody-drug conjugate to the front, paired with immunotherapy, would change that. Median progression-free survival improved from 7.8 months to 11.2 months, and treatment responses lasted significantly longer.UPDATE: Since this recorded conversation, the FDA has acted on the data discussed in this episode. On May 22, 2026, Datopotamab Deruxtecan was approved for first-line metastatic TNBC in patients who are not candidates for immunotherapy. On June 24, 2026, Sacituzumab Govitecan was approved for first-line use both as a single agent and in combination with pembrolizumab for PD-L1-positive disease (CPS ≥10). Consult with your care team for the most recent indications and availability of these treatment options.00:00 The trial that moves the best drugs first 00:31 Welcome back, Dr. Sara Tolaney 00:40 What ASCENT-04 set out to solve 02:00 Why many patients never reach second-line treatment 02:50 What PD-L1 status means for your treatment 04:12 The result: 7.8 to 11.2 months 05:29 What is an antibody-drug conjugate (ADC)? 06:33 Why TROP-2 is the target in triple-negative breast cancer 07:24 How immunotherapy works: taking the brakes off the T cell 09:01 Who was eligible for the trial 10:05 What "controlling" cancer actually means 11:44 Progression-free survival vs. duration of response 13:37 Dr. Tolaney reconsiders: what ASCENT-03 showed 15:51 How trial data reaches your oncologist's office 18:21 The testing checklist after a metastatic diagnosis 19:59 First-line treatment options today 22:27 The new paradigm: ADCs as the first-line backbone 23:51 What comes second line 25:29 Why tumor sequencing matters: somatic BRCA, TMB, trials 27:24 Twenty years of change in triple-negative breast cancer 29:28 Advice for a newly diagnosed patientSara M. Tolaney, MD, MPH is Chief of the Division of Breast Oncology and Associate Director of the Susan F. Smith Center for Women's Cancers at Dana-Farber Cancer Institute, and Associate Professor of Medicine at Harvard Medical School. She trained at Princeton University, UC San Francisco, Johns Hopkins University, and Dana-Farber Cancer Institute, and holds a Masters in Public Health (MPH) from Harvard University. She serves on the National Cancer Institute (NCI) Breast Cancer Steering Committee and is Vice Chair for Late-Stage Development in Breast Cancer for the Alliance for Clinical Trials in Oncology. She was principal investigator of ASCENT-04.

In 2024, Dominique Bieger knew something was wrong when she felt a tickling, biting sensation in her left breast.  After a series of mammograms, an echogram, an ultrasound and a vacuum assisted biopsy, she learned she had invasive ductal carcinoma, or breast cancer.  She would have to get a quadrant of the cancerous breast surgically removed.  Dominique was happy to learn she could avoid chemotherapy, instead for hormonal treatment, featuring letrozole, an aromatase inhibitor.  The letrozole left her hands, her feet and joints in severe pain.  She went off the letrozole and is investigating another post-surgery regimen.  Much of the pain is gone, leaving Dominique free to pursue a career as a chef.   When Dominique noticed this irritating sensation in her left breast, she did not immediately seek medical attention.  Because various cousins had been diagnosed with the BRCA mutation, in 2019, Dominique underwent a mammogram which showed she did not have the mutation.  She underwent another mammogram in 2023, which again showed her breasts to be cancer-free.   However, she had another mammogram done in 2025, along with a vacuum assisted biopsy.  Days later, the hospital called her and asked her to come in.  When she did, she was told she had invasive ductal carcinoma in a quadrant of her left breast, and the cancer had to be removed.   After a successful surgical procedure, Dominique was told she would not have to be put on chemotherapy.  Instead, a hormonal regimen would suffice.  Its primary ingredient was letrozole, an aromatase inhibitor.  She also underwent fifteen rounds of radiation treatment.   Dominique said the letrozole was very difficult as it resulted in pain in her hands, feet and joints.  At times, it also made her depressed.  To make matters worse, her work was done on the computer, and she was in too much pain to work. Dominique Bieger is off the letrozole.  She and her care team and trying to craft a regimen that will be effective without resulting in so much pain.   By way of advice, Dominique says if your doctor suggests a certain schedule for you to get a mammogram, to follow that schedule.  It can make the difference between staying in front of breast cancer and getting a diagnosis.   Additional Resources:   Dominique's YouTube channel:   https://www.youtube.com/@DominiqueJoileSmallWonders   Dominique's LinkedIn profile:   https://www.linkedin.com/in/dominique-florence-b-80354417    

The BRCA gene doesn't cause breast cancer — it removes one of your body's safeguards, and your metabolic terrain decides whether that ever matters. Liz & Becca break down where the 72% lifetime risk number actually comes from, why autopsies find cancer cells in women who died of something else, what tamoxifen does to your bones, thyroid and uterus, whether you can take HRT as a carrier, and the exact labs to run before anyone mentions surgery. Blunt, sourced, and not designed to make you comfortable. *** CONNECT:

Eleanor Terrett breaks down the state of play on the CLARITY Act just before the August recess deadline, unpacking the ethics language dividing Democrats and Republicans and why the DOJ-versus-state-AG enforcement fight remains the key sticking point. She also explains why the Blockchain Regulatory Certainty Act has suddenly become just as contentious, pitting developer protections against law enforcement concerns.Eleanor Terrett is the Co-Founder and Co-Host of Crypto in America, a leading independent outlet covering digital assets policy and regulation in Washington, DC.The Rollup is where the leaders of digital assets and finance converge. Live from the financial capital of the world.Timestamps:00:00 Intro04:28 The Ethics Provision Explained06:45 Why Democrats Say It's Not Enough09:22 60 Democrats Votes Needed11:24 The FTX Hangover Still Lingers14:26 BRCA's Developer Liability Fight17:10 Staking And Bank PushbackGuest Socials:Eleanor Terrett X: https://x.com/EleanorTerrettCrypto In America X: https://x.com/CryptoAmerica_Crypto In America Website: https://linktr.ee/cryptoinamerica_Partners: If you run concentrated liquidity positions you know the grind. Price moves, you're out of range, you're rebalancing at, like, 3am. 1inch Aqua lets you take a different approach. You can stack multiple positions on the same token balance instead of babysitting a dozen pools, and your tokens never leave your wallet. Your liquidity stays awake, so you can catch up on your sleep. Check it out at 1inch.com/aqua---Dinari - Over 230 1:1 backed tokenized stocks, ETFs & more with dividends. US-based SEC transfer agent. Available on 5+ chains & via API. https://dinari.com/---Relay is the fastest and most reliable way to swap any token on any chain. Learn more here: https://relay.link/bridge---Zama is an open source cryptography company that builds state-of-the-art Fully Homomorphic Encryption (FHE) solutions for blockchain.Learn more here: https://www.zama.org/---

In May 2022, Tina Calderone-Roth felt terrible. She was experiencing fatigue, shortness of breath and nausea.  She also gained close to 15 pounds in three days.  Nurses she knew suggested she go to the emergency department.  Two paracentesis procedures resulted in the removal of 6.5 liters of fluid.  Doctors initially noticed a large abdominal mass, but further tests indicated ovarian masses of 7cm and 10cm.  Tests also showed Tina had the BRCA-2 gene mutation.  She opted to, all at once, undergo a hysterectomy and bilateral oophorectomy.  A week after the procedure, it was learned there had been Stage 1B cancer in both ovaries.  Tina was next put on six rounds of chemotherapy with carbo-taxol, avastin and the PARP inhibitor, lynparaza.  Because of the BRCA-2 gene mutation and with it, the possibility of breast, she decided to get a bilateral mastectomy.  Tina reached survivorship and these days, while she can no longer run, she can jog and power walk.    Tina had been working for more than two decades in the care management sector of health care in 2022, when her health took a sudden turn for the worse.  She was feeling unusually tired, had shortness of breath and her weight shot up by 15 pounds in three days.  She had no idea what was going on, but consulted friends who were nurses, and they suggested she go to the emergency department, which she did in the middle of a workday.   Tina underwent a CT scan, ultrasound, electrocardiogram, blood work and genetic testing.  A subsequent pair of paracentesis procedure removed a combined 6.5 liters of fluid, which explained her sudden, sharp weight gain.  Those tests also showed she had a large abdominal mass. Further tests were conducted and they revealed two large ovarian masses, measuring roughly 7cm and 10cm.  Meanwhile, the genetic testing revealed Tina had the BRCA-2 gene mutation.  She did not want to have multiple surgeries, so she elected to have a hysterectomy along with the removal of both ovaries.  About a week later, it was determined the ovaries were cancerous.   She and her care team settled on a six-round chemotherapy regimen of carbo-taxol, avastin and the PARP inhibitor, lynparaza.  Like many dealing with chemotherapy, Tina was fatigued, had nausea and suffered hair loss, but got through it.  She was still concerned about the possibility of being diagnosed with breast cancer because of the gene mutation, so she decided to undergo a bilateral mastectomy.   If Tina Calderone-Roth's health before her diagnosis could be considered 100 percent, these days she considers her health to be at 90 percent.  While she can no longer run, Tina says she can jog and power walk.   Additional Resources:   Tina's Book:   "Where Fears Meets Faith," available on amazon.com and barnesandnoble.com, in paperback and Kindle          

In this episode of the Breast Cancer Now podcast, we speak to Tamara about her diagnosis of triple negative breast cancer, cancer in Black communities, and the impact of discovering she carries the BRCA2 gene mutation.Tamara opens up about the emotional weight of having to explain her cancer and her behaviour to the people around her. She also explores the stigma and mistrust that surrounds cancer in Black communities, and why culturally sensitive education is the key to improving outcomes.The conversation explores the feeling of dismissal Black women face in healthcare settings, and the incredible support Tamara experienced when she found Black Women Rising.Find support at Breast Cancer NowMore info about Younger Women Together coursesFind support at Black Women RisingFind support at UK Charity for Triple Negative Breast CancerFrom Me To You - Supporting Black Cancer Communities.You can also watch this episode on YouTube.Key Topics:2:50 Life before diagnosis5:36 Mara's breast cancer diagnosis11:08 Conversations about the BRCA gene mutation13:52 Understanding triple negative breast cancer20:37 Black women experiencing dismissal in healthcare22:48 What needs to be done to help improve healthcare for Black women?24:13 How Mara's diagnosis was received by her family and her community25:32 Mental health support at the point of cancer diagnosis28:58 Christian beliefs and breast cancer32:02 Difficulty talking with other people about your cancer diagnosis39:46 The power of the breast cancer community41:20 Body image after surgery for breast cancer44:01 Improving education in black Caribbean and black African communities51:18 Mara's work with Black Women Rising

If a Mount Rushmore of Epidemiology were to exist, Joseph F. Fraumeni Jr. would be etched into the face of the mountain, former NCI Director Ned Sharpless once told Stephen J. Chanock. Of the hundreds of scientists Fraumeni mentored, perhaps one of the closest was Stephen J. Chanock, his successor as director of the NCI Division of Cancer Epidemiology and Genetics, who worked with Fraumeni for 25 years. Fraumeni died on June 22. He was 93. Otis Brawley, co-editor of the Cancer History Project and the Bloomberg Distinguished Professor of Oncology and Epidemiology at Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, interviewed Chanock on the most recent episode of the Cancer History Project podcast. Brawley and Chanock looked back on Fraumeni's 50-year long career. His contributions to science included co-discovering the Li-Fraumeni syndrome and developing cancer maps, which visualize cancer rate data from every county in the U.S. His work served as a backbone for other major discoveries, such as the two-hit hypothesis by Alfred Knudson and BRCA genes.Fraumeni developed theories around how cancer works and tested them. “The mission statement of DCEG has been to understand the etiology of cancer through epidemiology and genetics as a means to prevention or early intervention,” Chanock said. “That's really the wisdom of Joe Fraumeni who lived that, and really developed the tools, the capabilities, and the workforce to pursue that.”As a result, Fraumeni established a vision of cancer's genetic susceptibility. His observations about diethylstilbestrol raised “a very revolutionary idea” that early exposures could result in precancerous conditions and develop into cancers decades later. The cancer maps added a new attention to cancer caused by environmental exposures. “These patterns were very important, which led to understandings about what was going on post-World War II and [how] certain occupations are associated with select cancers,” Chanock said. “This led to the birth of a whole set of cohorts and case control studies to look at asbestos, smelters, occupational hazards and smokeless tobacco use in the South.” The goal was always to help patients, many of whom had no options at the start of Fraumeni's career. “What Joe was envisioning was the more we understand, the more we can be honest and explain to our patients who develop cancer or may develop cancer, what we could be done to prevent or decrease that risk,” Chanock said. A transcript of this conversation, along with an archive of related content, is available on the Cancer History Project: https://cancerhistoryproject.com/article/joseph-f-fraumeni-jr/ 

Dr. Jenn Simmons — former fellowship-trained breast surgeon, functional medicine physician, and founder of Perfection Imaging — joins Dr. Will Cole in New York for one of the most important conversations about women's health this podcast has ever had. She shares the family loss that launched her career, her own cancer diagnosis at 46 that led her to functional medicine, and why she walked away from a surgical career to build something entirely different. She makes a clear-eyed, evidence-backed case against mammograms as a standard screening tool — citing multiple large-scale clinical trials — and introduces two safe, effective alternatives: the ARIA tears test and QT sound wave imaging. She also addresses the BRCA genetic conversation, DCIS overtreatment, and why breast cancer must be understood as a metabolic, environmental, and mitochondrial disease. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Start your free trial at SHOPIFY.COM/willcole!For up to 65% off your order, head to VeracityHealth.co and use code ABSOLUTELY.Visit www.sleep.me/willcole to get up to $255 off your Chilipad 2.0 with code willcole. This special offer is available for Art of Being Well listeners — and only for a limited time!Use the links in my show notes to check your registration, get registered, or receive election reminders. You can also visit vote.online or @vote on Instagram for more information.Check Your Registration - https://tools.vote.online/embeds/check-your-registration?partnerId=cbc1e590 Get Election Reminders - https://tools.vote.online/embeds/get-election-reminders?partnerId=cbc1e590 Register To Vote - https://tools.vote.online/embeds/register-to-vote?partnerId=cbc1e590 Pledge To Register - https://tools.vote.online/embeds/pledge-to-register?partnerId=cbc1e590Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The CLARITY Act continues to gain support from several stakeholders, with the latest being the Major Cities Chiefs Association (MCCA), a major law enforcement group. Despite this, the odds of passing remain at 30%, with Democrats and TradFi still pushing for amendments in DeFi provisions. ~This episode is sponsored by Tangem~ Tangem ➜ https://bit.ly/TangemPBN Use Code: "PBN" for Additional Discounts! GUEST: Brian Nistler - Head of Policy & Associate General Counsel, Protocol Growth at Uniswap Foundation Follow Briand on Twitter➜ https://x.com/N0th1n3 00:00 intro 00:10 Sponsor: Tangem 00:30 Countdown 01:00 Lummis: Banks are about to break Republicans too 03:10 Odds collapse 04:15 Why did Cortez put out a press statement? 05:50 Who told her to put out a premature statement? 07:00 Negotiations ruptured? 09:00 Press statement timing is suspicious 10:00 Constitution takes priority 11:30 Russia vs Telegram: Are we becoming Russia without BRCA? 12:40 Privacy under threat? 14:15 More important to Banks? yield ban or DeFi ban? 15:40 Bloomberg backs DTCC over DeFi 18:00 Uniswap Permission pools 20:50 Innovation offshore 21:45 $UNI Burn Will Continue Even Without CLARITY #Crypto #Ethereum #Uniswap ~Dirty Trick to KILL DeFi

Welcome to Grid Talk, this week we are talking to Ryan Clarke from the UK Xray teamJust a great chat about what Ryans been up to, Including his National series so far, winning the over 40's at the BRCA veterans meeting, and we go over his new electronics package with Elcram, with a trip down memory lane talking about when he won his final at the Hudy Euros after a harsh but fair 10 second penalty!!All that and more on this weeks show!#CMLdistribution#SchumacherRacing#Willspeed#GTRC

What if one test could change the future for you and your family? Kathy Baker knows firsthand. After a breast cancer diagnosis and years of encouragement from her oncologist, genetic testing revealed a BRCA mutation that ultimately saved her life. In this episode, Kathy shares her personal journey, explains why hereditary cancer awareness matters, and offers practical guidance for anyone wondering whether genetic testing is right for them.

What if hitting prostate cancer earlier and harder is the key to delaying disease progression and sparing patients from invasive salvage therapies? In this follow-up to his i3 Health Virtual Tumor Board, Stephen Freedland, MD, Cedars-Sinai Medical Center, unpacks practice-changing data from ASCO that is actively reshaping care algorithms across the prostate cancer continuum. Dr. Freedland dives into the breakthrough TALAPRO-3 trial—exploring why talazoparib plus enzalutamide is making waves across diverse HRR alterations (including BRCA and ATM)—and analyzes how the PROTEUS trial's 35% reduction in subsequent salvage therapies could redefine surgical planning for high-risk localized disease. Plus, get an insider's look at what's on the horizon with PSMA PET imaging, T-cell engagers, and AR degraders.

0:00 The friend he hasn't seen since sixth grade 5:16 Angelina Jolie, BRCA, and the 20% nobody tells women about 18:23 What a cancer cell actually is - and why tumors evolve 26:31 How cancer actually kills you, and what a seizure is 32:14 The last cigarette: why he can't take the test every week 46:27 The best medicine in the world, and who can't get to it 1:03:23 Telling a family there's nothing left Noam hadn't seen Kenan Onel since high school in Ardsley, where Onel graduated first in the class and Noam, by his own account, drifted somewhere well below. Fifty years later Onel runs genetics and genomics at Roswell Park - the only comprehensive cancer center in all of western New York - and Noam has one thing he wants to ask him about. He's afraid of cancer. His grandfather died of it. His father died of it. He's taken the Grail blood test, it came back clean, and he wants to know why he can't just take it every week. What follows is part reunion and part interrogation. Onel explains what a cancer cell actually is, why tumors evolve like finches in the Galapagos, and what is physically happening to someone during a seizure. He explains how cancer kills - the mechanism, organ by organ. And he tells Noam that the test he's counting on just failed its biggest trial in the UK, which sets off the real argument of the hour: whether a guideline written for a population means anything at all to the one person sitting in the chair. Then, near the end, Noam asks how you tell a family there's nothing left to offer. The answer is the best thing in the episode. Also: the 20% of women who are high-risk and have never been told, the doctor who warned Noam that Pellegrino was bad for his son's bones, a scan booked by 4pm the next afternoon, and one entire podcast without mentioning Israel. Dr. Kenan Onel is Chief of the Division of Genetics and Genomics and Director of the Center for Precision Oncology and Cancer Prevention at Roswell Park Comprehensive Cancer Center. Live from the Table is the official podcast of the world-famous Comedy Cellar.

0:00 The friend he hasn't seen since sixth grade 5:16 Angelina Jolie, BRCA, and the 20% nobody tells women about 18:23 What a cancer cell actually is - and why tumors evolve 26:31 How cancer actually kills you, and what a seizure is 32:14 The last cigarette: why he can't take the test every week 46:27 The best medicine in the world, and who can't get to it 1:03:23 Telling a family there's nothing left Noam hadn't seen Kenan Onel since high school in Ardsley, where Onel graduated first in the class and Noam, by his own account, drifted somewhere well below. Fifty years later Onel runs genetics and genomics at Roswell Park - the only comprehensive cancer center in all of western New York - and Noam has one thing he wants to ask him about. He's afraid of cancer. His grandfather died of it. His father died of it. He's taken the Grail blood test, it came back clean, and he wants to know why he can't just take it every week. What follows is part reunion and part interrogation. Onel explains what a cancer cell actually is, why tumors evolve like finches in the Galapagos, and what is physically happening to someone during a seizure. He explains how cancer kills - the mechanism, organ by organ. And he tells Noam that the test he's counting on just failed its biggest trial in the UK, which sets off the real argument of the hour: whether a guideline written for a population means anything at all to the one person sitting in the chair. Then, near the end, Noam asks how you tell a family there's nothing left to offer. The answer is the best thing in the episode. Also: the 20% of women who are high-risk and have never been told, the doctor who warned Noam that Pellegrino was bad for his son's bones, a scan booked by 4pm the next afternoon, and one entire podcast without mentioning Israel. Dr. Kenan Onel is Chief of the Division of Genetics and Genomics and Director of the Center for Precision Oncology and Cancer Prevention at Roswell Park Comprehensive Cancer Center. Live from the Table is the official podcast of the world-famous Comedy Cellar.

What if breast cancer risk is not determined only by your genes or family history? In this episode, Dr. Taz sits down with double board-certified breast cancer surgeon and lifestyle medicine physician Dr. Kristi Funk to discuss why breast cancer is becoming more common, especially among younger women, and what women can do to better understand and potentially reduce their risk.Dr. Funk explains why 95% of women diagnosed with breast cancer do not have a BRCA mutation and why 87% do not have a first-degree relative with the disease. Together, Dr. Taz and Dr. Funk explore how food, alcohol, exercise, body weight, stress, inflammation, environmental toxins, sleep, and hormone therapy may influence breast health.They also break down some of the most confusing questions surrounding breast cancer screening and treatment. Do mammograms cause cancer? Is ultrasound a good alternative? When should women begin breast exams? Are some cases of stage zero breast cancer being overtreated? And how much does menopause hormone therapy actually increase breast cancer risk?Breast cancer screening is important, but screening and prevention are not the same thing. Understanding your individual risk factors can help you have better conversations with your doctor and make more informed decisions about your health.If you are navigating cancer treatment or recovery, concerned about inflammation, or want personalized support for your hormones and nutrition, explore related Hol+ care options here:Cancer Support:https://holplus.co/services/cancer-support/Inflammation:https://holplus.co/conditions/inflammation/Hormone Balancing:https://holplus.co/services/hormone-balancing/About Dr. Kristi Funk:Dr. Kristi Funk is a double board-certified breast cancer surgeon, lifestyle medicine physician, bestselling author, and international speaker. She graduated from Stanford University and received her medical degree from UC Davis before completing her surgical residency and breast cancer fellowship.Dr. Funk previously served as Director of the Cedars-Sinai Breast Center and co-founded the Pink Lotus Breast Center in Los Angeles, where she continues to practice. She has helped thousands of women navigate breast health and breast cancer, including Angelina Jolie and Sheryl Crow. She is also the author of Breasts: The Owner's Manual and the founder of the Cancer-Kicking! Summit.Connect with Dr. Kristi Funk:https://www.instagram.com/drkristifunkhttps://pinklotus.com/About Dr. Taz:Dr. Tasneem Bhatia, also known as Dr. Taz, is a triple board-certified integrative medicine physician, bestselling author, and founder of hol+, a multi-location integrative medicine practice.Learn more: https://doctortaz.com/aboutStay Connected:Connect further to Hol+ at https://holplus.co/ - Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Book a Hol+ Consultation: https://holplus.co/locations/virtual/Follow Dr. Taz on Instagram:https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)Chapters0:00 Why breast cancer is rising6:20 Why most cases are not genetic14:53 The biggest breast cancer risk factors34:25 How stress and inflammation affect risk40:33 Breast exams, mammograms, and screening49:40 Are we overtreating stage zero breast cancer?57:20 Hormone therapy and breast cancer risk

A deluxe edition of The Sprina Sessions is live!

Jackie Tohn (Nobody Wants This, The Boys, GLOW) is an actress, comedian, and musician. Jackie joins Armchair Expert to discuss growing up on Long Island with two gym-teacher parents, discovering her BRCA mutation after her father's cancer diagnosis, and becoming an advocate for genetic testing and preventative care. Jackie and Dax talk about clawing through Hollywood as a musician and comic, learning to pivot instead of wait for permission, and finally being able to calm down after Nobody Wants This. Jackie explains the exhaustion of making life-or-death choices, how anxiety changes once the thing you fear actually happens, and the freedom of not having to be “on” for every room.Check Allstate first for a quote that could save you hundreds: https://www.allstate.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Rachael Rudel is having one of the biggest breakthrough seasons in American distance running. After years away from elite racing, she’s back in a big way. This spring she became the top American woman at both the Boulder Boulder and the B.A.A. 10K, finished second overall at the B.A.A. 10K in a personal best 31:31, placed runner-up at the USATF 4 Mile Championships, and broke the course record at the Horsetooth Half Marathon. Rachael shares the story behind her journey, from battling an eating disorder that stemmed from an undiagnosed case of celiac disease, to making the difficult decision to undergo a preventative double mastectomy after testing positive for the BRCA gene mutation. She talks openly about rebuilding her relationship with running, returning to competition after nearly a decade away from the elite level, and why she believes she’s still only scratching the surface of her potential. We also dive into her work with Front Range Elite, training under coach David Roche and now recently beginning to work with agent Josh Cox, balancing a demanding full-time career alongside professional-level racing, and what’s next as she eyes the marathon and beyond. Rachael is one of the most refreshing personalities in the sport right now, and I absolutely loved this conversation. Topics discussed: Rachael’s breakout 2026 racing season Finishing second at the B.A.A. 10K and becoming the top American Growing up as a multi-sport athlete Being recruited to Colorado State as a jumper before becoming a distance runner Living with undiagnosed celiac disease Recovering from an eating disorder Undergoing a preventative double mastectomy after testing positive for the BRCA gene mutation Finding joy in running again after stepping away from elite competition Working full-time while competing at a national level The culture and mission of Front Range Elite Why she’s taking a patient approach toward the marathon Learning to race fearlessly while staying healthy What’s next for the second half of the season Get connected with Rachael’s team: Front Range Elite Support our Sponsors:  HUUG makes high-quality bras and underwear designed to actually fit and support your body through every phase of life. Their pieces are comfortable, functional, and built for movement, making them a go-to for everyday wear, running, and training alike. Use the code Lindsey for 15% off at huug.com. Be the first to know about my Indianapolis Monumental Marathon & Half Marathon group training! Previnex – I start my day with Previnex Gut & Green Superfoods and end it with their Sleep Health Plus. I trust Previnex because their products are third-party tested, backed by science, and designed to help support energy, recovery, sleep, immunity, and healthy aging. Use code ANOTHER for 15% off your first order at Previnex.com. If you've already used that code, you can also use LindseySuperfoods, LindseySleep, or LindseyStrength depending on the product you're trying. Tailwind NutritionTailwind Nutrition creates all-in-one endurance fuel and hydration products designed to be easy to digest while providing calories, electrolytes, and hydration during long efforts. Their products are built specifically for endurance athletes who want simple, effective fueling without GI issues. Go to tailwindnutrition.com/another and use the code “Another20” for 20% off your first order. Lagoon Sleep — If you're ready to upgrade your sleep, Lagoon pillows are truly a game changer. Their customizable pillows are designed to help you fall asleep faster, stay cool, and wake up without neck or shoulder pain. You can adjust the fill to make it perfect for you. Save 15% by going to https://lagoonsleep.com/lindsey and using the code LINDSEY at checkout. The post Episode 694: Rachael Rudel – After a Decade Away, She’s Now One of America’s Best appeared first on SandyBoy Productions.

T Time Stamps : 00:00 intro Max lefty catch up  25:26 - BRCA 1:8 Nats  30:07 TNR Arenacross  34:46 - Jermaine Robinson Fastest 1:8 Racer in Cali!  38:49 - Cali King of Club Racing  41:11- LCRC - Party Rock Race  42:40 -  JConcepts INS RD #3  44:10 - Schumacher dominates on carpet at INS 49:07 - Domnic Paccione Best Spec Driver in the World & Spec vs Mod tangents  1:03:20 - ⅛ needs a mechanical difference  1:08:20 - SWORKZ LCG Conversion  1:34:09 - More Vintage Releases 1:38:40 -Light Weight Gears

In this episode of the Breast Cancer Now podcast, we explore the role of genetics in cancer risk, including BRCA1 and BRCA2 gene mutations, specifically in Jewish populations.Naomi shares her powerful story after discovering she carries the BRCA2 gene mutation following the loss of her mum to ovarian cancer. With an 80% lifetime risk of breast cancer, She faced life-changing decisions, and opted for risk-reducing surgery.Naomi speaks about what it's like to live with that knowledge, how it shaped her choices, and why taking preventative action gave her a sense of control. She also shares the impact of her gene mutation on her children, and how they've dealt with it as a family.We're also joined by Josh from Jnetics, a Jewish genetic disorders charity, who explains the science behind BRCA gene mutations, why they increase cancer risk, and why they are more common in people with Jewish ancestry. He also outlines how testing works, who may be eligible, and what support is available.Breast Cancer NowWebsite: https://breastcancernow.orgFree helpline: 0808 800 6000Jewish BRCA Testing Programme (NHS England)Register interest: https://www.jewishbrca.orgHelpline: 020 3437 6001Jneticshttps://www.jnetics.orgChai Cancer Carehttps://www.chaicancercare.orgYou can also watch this episode on YouTube.Key topics:1:29 Getting to know Naomi and Josh4:00 A history of cancer in Naomi's family7:50 Naomi is tested for the BRCA gene mutation9:35 What is a genetic mutation or gault?12:20 Why is the BRCA gene mutation more common in Jewish populations?17:24 What is BRCA, how does it work, and why does it break?20:38 Naomi's increased risk of cancer23:32 Naomi makes the choice to have risk-reducing surgery27:01 The psychological impact of risk-reducing surgery28:34 Support for carriers of gene mutations31:53 How to get tested for BRCA gene mutations35:52 Coping with the fear of having genetic testing37:52 Naomi decides how to deal with her daughters potentially being BRCA carriers39:47 Dealing with feelings of guilt passing on a genetic mutation to a child41:15 Preventing gene mutations with IVF42:20 Research into fixing faulty genes44:06 Cultural barriers to genetic testing within Jewish populations46:51 Hope for the future of genetic mutations50:08 More information for people with Jewish heritageBRCA gene, BRCA2, breast cancer risk, genetic testing UK, hereditary cancer, ovarian cancer risk, mastectomy prevention, cancer genetics, Jewish BRCA, NHS genetic testing, breast cancer awareness UK

A bi-weekly news show informing you on the latest in Bitcoin, privacy and open source tech hosted by Ungovernables, Max and Q. AOB• Holiday season is over• UK no longer melting• Samourai updatesNEWS• GitHub permanently bans Rust Lightning (LDK); Corallo moves Bitcoin dev infra to self-hosted Forgejo - Bitcoin Magazine: Corallo urges Bitcoin projects to exit GitHub after Rust Lightning ban• Sparrow Wallet Apple developer-account scare resolved - Bitcoin Magazine / Craig Raw / Sparrow Wallet• FISA Section 702 lapses for the first time since 2008 - EFF: Victory, 702 Has Expired• Canada's surveillance-and-speech week: Lawful Access bill (C-22) rammed to a June 19 deadline, "Combatting Hate" Act (C-9) gets royal assent June 18 - EFF: Canada Is Forging Ahead with Its Dangerous Surveillance Bill / Canada.ca: stronger hate crime protections become law• US CBDC ban through 2030 heads to the President's desk - House Financial Services Committee• Developer-protection carve-out (BRCA) being sanded down as CLARITY Act stalls; passage odds cut to 50-50 - Bitcoin Magazine: Galaxy Research cuts CLARITY Act passage odds• Bull Bitcoin secures MiCA license in France while keeping self-custody/privacy model - Bitcoin Magazine / Bull Bitcoin• ESMA tells unlicensed crypto providers to wind down as MiCA deadline arrives - ESMA public statement PDF• LND zero-timestamp DoS vulnerability publicly disclosed - Bitcoin Optech #411RELEASESWallets• Envoy v2.3.0-beta - 2026-06-22Redesigned Send flow with inter-account transfers, message signing, Address Explorer, sub-sat fee rates, and custom block-explorer support, plus Passport Prime pairing/Bluetooth reliability fixes. Disclose it is ours.• Zeus v13.1.0 - 2026-06-17Feature release: Cashu multi-mint sends, queue-less Nostr Wallet Connect payments on iOS, CLINK noffer support, and Cashu-token detection in URLs. Strong ecash plus Nostr-native payments stack for a self-custodial Lightning wallet.• Zeus v13.1.1 - 2026-06-26Patch: fixes TLS cert verification for LND/CLN REST over Tor and a currency-converter input bug.• Phoenix 2.8.1 - 2026-06-18Adds an iOS debug screen for signing swap-in transactions and fixes an Android amount-display bug, on updated lightning-kmp.• Blockstream Green iOS 5.5.0 - 2026-06-15Adds support for paying LNURL, BOLT12, and BIP-353 payment instructions, improves Lightning invoice handling, and shows funding fees in the receive flow.• Blockstream Green Desktop 3.4.1 - 2026-06-17Adds BOLT12 offer descriptions and updates GDK to 0.77.6. Secondary to the iOS release, but it reinforces the same BOLT12/BIP-353 direction.• Blink Mobile 3.0.1 - 2026-06-26Pre-release build that continues Blink's self-custodial wallet implementation, including wallet creation, seed backup/recovery, Blink Lightning address, LNURL pay, and Stable Balance with BTC-USD conversion. Mention only as a prerelease / watch item.Lightning / node ops• Core Lightning 26.06.2 - 2026-06-29Point release recommended for minimal OS setups and Docker images lacking root TLS certificates. Late-breaking / record-day item if recording after June 29; not a lead, but useful for node operators.Self-hosting / payments infra• BTCPay Server v2.4.0 - 2026-06-25Major release: multisig wallet setup, loginless passkey auth, and granular per-wallet permissions. Breaking: removes the LNBank and Lightning Charge backends.Bitcoin / wallet infrastructure• Liquid GDK 0.77.6 - 2026-06-16Adds Python 3.14 wheels and fixes singlesig GDK use over Tor that broke after a ureq dependency update. Developer/infrastructure note rather than listener-facing wallet news.Hardware / multisig / inheritance• Nunchuk 2.6.0 - 2026-06-17 (Blog Post: https://nunchuk.io/blog/phased-rollout )Phased rollout of the off-chain inheritance protocol, plus fixes and performance work. Self-custodied estate planning for multisig users.P2P / no-KYC trading• Mostro v0.17.5 - 2026-06-16Anti-abuse bonds harden the Nostr-based P2P marketplace while staying non-custodial. Adds multi-source price aggregation and maker-timeout penalties.• BULL Wallet v6.11.1 - 2026-06-22CSV export, payment notes, auto swap-claim retries, better Electrum reliability, experimental Linux desktop support. • Peach Bitcoin 0.69.0 - 2026-06-25Faster funding-flow sync, but ships a new EU-compliance sign-up step. Worth naming the privacy/compliance tradeoff for a no-KYC-leaning audience.On-chain privacy / coinjoin• Ashigaru Desktop 1.0 - 2026-06-24 Ashigaru Desktop 1.0.0 (June 19, 2026) is the inaugural stable release of the Whirlpool coinjoin desktop wallet, shipping Tx0/zeroleak mixing with Premix/Postmix/Badbank account management, built-in Tor, Mix To for routing postmix funds offline, a receive-only attack-surface reduction model, BIP-329 label import/export, and an offline BIP47 message verifier. It also adds a polished dark-theme UI with live coinjoin progress tracking, full cross-platform packaging (Windows/macOS/Linux plus headless server builds), reproducible builds, and BIP47-signed three-step release verification.• JoinMarket NG 0.33.0 - 2026-06-24Correction/update from earlier 0.32.0 note. 0.33.0 adds forced-address-reuse defences, a config center, TUI send validation, wallet history API work, and fidelity-bond / tumbler fixes.• Wasabi Wallet 2.8.0 - 2026-06-28This release adds P2P sync for compact filters, pay-in-coinjoin, sub-1 sat/vByte fees, payment batching, a Scheme scripting language, Signet support, and Tor forward compatibility. It also broadens platform reach with arm64 Linux, Tails, and Whonix support.• Payjoin Dev Kit payjoin-mailroom 0.1.2 - 2026-06-26Hardens the combined Payjoin Directory and OHTTP Relay with bounded file-descriptor usage, recovery from transient accept errors, database/per-request metrics, and unified mailbox TTL.General wallet / spend• Stack Wallet 2.6.0 - 2026-06-27Adds CakePay gift-card support. EDUCATION• The Fed Is Working on a CBDCThe Rage reports that despite public denials, the Fed is internally researching CBDC design. A concrete surveillance-money piece that pairs directly with the 702 lapse for a “financial panopticon” segment. Also pair with the new ROAD to Housing Act CBDC-ban item: the ban runs only through 2030, which is the punchline.• BIP 110 Fork Simulator / explainerInteractive explainer of the BIP 110 “Reduced Data Temporary Softfork”: activation mechanics, what gets restricted, and how the data-filtering debate could split consensus.• How-To Guide: Running an Ecash MintHands-on Cashu / LNbits + Nutshell mint walkthrough. Ecash is the privacy tech of the moment; a good “run your own mint” counterweight to “just use a wallet.”• Bitcoin Privacy in 2026: A Practical GuideDated 2026-06-04, outside even the grace cutoff, so use as evergreen rather than news. Good “where do listeners actually start” resource.• Bitcoin Optech #411Carries the LND zero-timestamp DoS disclosure plus the usual protocol-discussion roundup. Patch reminder for node runners.• Bitcoin Optech #410Summarises an active dev debate to remove opt-in RBF signaling because it now mainly fingerprints the wallet that created the transaction, plus Sparrow Silent Payments, JoinMarket, and Ark items.KEEP AN EYE ON• EU “Chat Control” final trilogue - Patrick Breyer / fightchatcontrol.euThe fourth and likely final trilogue on the permanent CSAM-scanning regulation is set for Monday 2026-06-29. Member states have reportedly dropped the forced encrypted-message-scanning mandate, but the Council text would still codify “voluntary” scanning and extend the interim derogation, with formal adoption expected in July. Outcome not yet known as of record date.• MiCA enforcement after July 1 - ESMA / Bull BitcoinBull Bitcoin is the self-custody-friendly example to watch, while ESMA's wind-down warning is the enforcement backdrop. After July 1, check which EU-accessible services remain available, which providers stop onboarding, and whether “compliant but non-custodial” survives contact with implementation.TO DONATE TO ROMAN'S DEFENSE FUND: https://freeromanstorm.com/donateHELP GET SAMOURAI A PARDONSIGN THE PETITION ----> https://www.change.org/p/stand-up-for-freedom-pardon-the-innocent-coders-jailed-for-building-privacy-tools DONATE TO THE FAMILIES ----> https://www.givesendgo.com/billandkeonneSUPPORT ON SOCIAL MEDIA ---> https://billandkeonne.org/VALUE FOR VALUEThanks for listening you…

She's back—and this time, she brought a book. Dr. Elisa Port, Chief of Breast Surgery at Mount Sinai, returns to Lipstick on the Rim to talk about her new book, The Breast Advice. With 25 years of experience and celebrity patients including Chris Evert, Jill Martin, and Rita Wilson, she's putting everything she knows into one place so women don't have to sort through the noise alone. We get into personal risk, dense breasts, BRCA testing, mammogram guidelines, and what actually happens after a diagnosis—including why more options doesn't mean more treatment. This one is for everyone avoiding the topic or already deep in it. A Sony Music Entertainment production.  Find more great podcasts from Sony Music Entertainment at sonymusic.com/podcasts and follow us at @sonypodcasts  To bring your brand to life in this podcast, email podcastadsales@sonymusic.com Mentioned in the Episode: The Breast Advice Book Learn more about your ad choices. Visit podcastchoices.com/adchoices

With the July 4th deadline closing in, the odds of getting BRCA passed in a form the industry can accept are looking worse by the week. Ken Egan, Zach Cohen, and Zach Shapiro break down where the Blockchain Regulatory Certainty Act and the broader CLARITY Act stand, why the opposition has had too much time to rally, and what the final software-developer protections might actually look like. They also unpack Illinois' first-of-its-kind 0.2% digital-asset "privilege tax" and what it signals for self-custody.

Kyle Olney joins THE Bitcoin Podcast to discuss Bitcoin policy, open-source software, AI, privacy, and the growing battle between freedom technology and government control. We examine the Clarity Act and BRCA, what they mean for Bitcoin developers and privacy tools, and why developer protections are critical fight for the future of open-source innovation in America. Kyle also explores the parallels between Bitcoin and AI, the risks of restricting access to advanced models (e.g. Anthropic's Fable), and why open-source technology is essential for preserving competition, privacy, and individual liberty. Finally, we zoom out to discuss technological acceleration, generational leadership, the Fourth Turning, and the case for a modern cypherpunk revival. If you're interested in Bitcoin, AI, privacy, and the future of freedom technology, this episode is for you. FOLLOW KYLE: X: https://x.com/KyleOlney PARTNERS & DISCOUNTS: LEDN: Bitcoin-backed lending. Go to ledn.io/walker and unlock liquidity WITHOUT selling your bitcoin. BLOCKSTREAM JADE: BLOCKSTREAM JADE HARDWARE WALLET: Head to https://store.blockstream.com/ and use coupon code WALKER for 10% off! BDIC™ is building an insurance marketplace on the bitcoin standard. Sign up for the waitlist at: http://bdic.io/walker Get a FREE MONTH of Bitcoin miner hosting via https://abundantmines.com/walker/ Buy Bitcoin with River: http://partner.river.com/walker GET FOLD ($10 in bitcoin): https://use.foldapp.com/r/WALKER JOIN THE SUBSTACK TO GET NEW EPISODES DELIVERED STRAIGHT TO YOUR INBOX: https://walkeramerica.substack.com/ If you enjoy THE Bitcoin Podcast you can help support the show by doing the following: FOLLOW ME (Walker) on @WalkerAmerica on X | @TitcoinPodcast on X | Nostr Personal (walker) | Nostr Podcast (Titcoin) | Instagram Subscribe to THE Bitcoin Podcast (and leave a review) on Fountain | YouTube | Spotify | Rumble | EVERYWHERE ELSE

Marty sits down with Kyle Olney to discuss the government's escalating war on freedom tech, from the BRCA's dangerous developer loopholes and sudden AI export controls to the urgent need for open source software as the last line of defense against surveillance and licensing regimes. Kyle on X: https://x.com/KyleOlney STACK SATS hat: https://tftcmerch.io/ Our newsletter: https://www.tftc.io/bitcoin-brief/ TFTC Elite (Ad-free & Discord): https://www.tftc.io/#/portal/signup/ Discord: https://discord.gg/yHGkvYxdqT Opportunity Cost Extension: https://www.opportunitycost.app/ Shoutout to our sponsors: Bitkey https://bitkey.world/ Aven https://www.aven.com/bitcoin CrowdHealth https://www.joincrowdhealth.com/tftc Unchained https://unchained.com/tftc/ Lygos https://lygos.finance/ Salt of the Earth: https://drinksote.com/tftc Join the TFTC Movement: Main YT Channel https://www.youtube.com/c/TFTC21/videos Clips YT Channel https://www.youtube.com/channel/UCUQcW3jxfQfEUS8kqR5pJtQ Website https://tftc.io/ Newsletter tftc.io/bitcoin-brief/ Twitter https://twitter.com/tftc21 Instagram https://www.instagram.com/tftc.io/ Nostr https://primal.net/tftc Follow Marty Bent: Twitter https://twitter.com/martybent Nostr https://primal.net/martybent Newsletter https://tftc.io/martys-bent/ Podcast https://www.tftc.io/tag/podcasts/

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this episode, Peter explores the critical topic of breast cancer screening, examining why thousands of women continue to die from breast cancer each year despite the availability of effective screening tools. He explains the strengths and limitations of current screening strategies, reviews the recommendations from major medical organizations, and discusses why screening guidance can often seem confusing or contradictory. Peter outlines a practical framework for understanding breast cancer risk and personalizing screening decisions, including when to begin screening, how frequently to screen, and which imaging modalities may be most appropriate based on an individual's risk profile. Throughout the episode, he emphasizes that while population-based guidelines provide an important foundation, optimizing outcomes requires a more personalized approach aimed at helping women make informed screening decisions that can improve the chances of early detection and successful treatment. We discuss: Why women still die from breast cancer: the benefits of screening, the problem of under-screening, and the need for risk-based screening strategies [1:45]; Current screening recommendations, why they differ between organizations, and the importance of personalized screening decisions [6:30]; A framework for personalizing screening [8:45]; Assessing baseline breast cancer risk: genetics, family history, breast density, lifestyle factors, and the role of risk calculators in personalized screening [9:30]; Balancing cancer detection and false positives: how breast cancer risk influences screening intensity and imaging choices [17:45]; Mammography as the foundation of breast cancer screening: detecting ductal carcinoma in situ (DCIS) and the advantages of 3D versus 2D mammography [21:00]; MRI for high-risk women: the benefits of supplemental screening, abbreviated MRI, and the emerging role of contrast-enhanced mammography [23:00]; The role of ultrasound: supplemental cancer detection, diagnostic evaluation, and limitations compared with mammography and MRI [26:00]; Choosing the right breast cancer screening strategy: imaging modality selection, screening hierarchies, and the importance of imaging center quality [28:00]; How often should you screen for breast cancer? [30:15]; At what age should you start screening? [37:30]; Breast cancer in younger women: aggressive tumor biology, BRCA-related risk, breast density, and individualized decisions about when to begin screening [41:45]; Inflammatory breast cancer, the limitations of screening mammography for symptomatic disease, and the importance of promptly evaluating new breast symptoms in both women and men [44:45]; From risk assessment to personalized screening: a practical framework for reducing breast cancer mortality through earlier and more effective detection [46:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

CoinDesk's The Policy Protocol hosts Rebecca Rettig and Renato Mariotti unpack the CFTC's 267-page proposed rule-making around prediction markets and event contracts, plus the letter from crypto CEOs backing the BRCA. And, a debate between John Lothian and Udesh Jha, Head of Exchange Analytics at Kalshi, over whether crypto perpetuals are properly classified as futures or swaps. - Read more from Ari Redbord about the mixer indictment under 1956: https://www.linkedin.com/posts/ari-redbord_in-the-midst-of-debate-around-clarity-activity-7470924721635794944-8yUy?utm_source=share&utm_medium=member_ios&rcm=ACoAADHl20UBUd56sB8eTJ0w5gv3WIBQo2eJ6f0 - Timecodes: 00:00 Welcome to The Policy Protocol 01:10 CFTC's 267-Page Prediction Markets Rule 03:10 60+ CEOs Back the BRCA 05:30 The Perpetuals Debate 07:43 John Lothian's Case: Do Perpetuals Look Like Swaps? 09:45 Kalshi's Udesh Jha on Funding Rates and Cost of Carry 12:43 Would Swap Status Shut Out Retail? 16:45 Is Kalshi Making the Rules Up? 19:25 John's Closing: Market Manipulation Concerns 20:46 Udesh's Closing: 'Regulation First' 23:29 Person of the Week: State Regulators 23:38 Illinois' Digital Asset Trading Tax 24:20 NY DFS Aligns With Genius

The NNRC News Show is back with another episode! Max and Lefty explore some breaking industry news as Javier Garcia gets appointed as IFMAR section chairman, the biggest races in the past few weeks such as the Jconcepts ONS at Adrenaline and ETS at Apeldoorn as well as the coolest new releases in the RC Market! Time Stamps: 0:00 - Intro & Catchup 8:52 - Industry News  9:40 - Javier Garcia Interim IC Director at IFMAR  24:41 -Rick Howhart Departs from AR after 19 years  29:28 - Race Results  30:33 - JBRL  33:05 - Brca 1/10 the Nats rd #3 34:41 -Spanish Nats RD #3  38:25 - ONS RD #2 44:50 - GT Euros 51:22 - Italian Race  57:48- Barrufolo Wins Kyosho Masters  1:00:23 - ETS RD #1 1:17:29 - New Releases - AE Drops1/8th Platform  1:34:56 - Sparko F8 SE  1:36:16 - AE FTE RC10 Truck  1:40:34 - Avalon TC Body  2:11:02 - 3d Printed nitro pipe Manifold?  2:15:10 - R1 Wurks Titanium Driveshafts  2:18:24 -TLR RPP is Back  2:21:04 -  David Ronnefalk Buys Latera Racing  2:25:26 - Max Rear vs Mid Motor Rebuttal  2:38:27 - Conclusion 

The Women's T20 cricket world cup begins on Friday. Nuala McGovern talks to Clare Connor, former England women's captain, now the outgoing Managing Director of England Women. Over her 18 years in the job Clare has overseen the professionalisation of the women's game as well as a big boost in the grassroots participation.Conservative Party leader Kemi Badenoch is arguing that the Public Sector Equality Duty should be scrapped. This duty exists to make public authorities think about things like discrimination and the needs of people who are disadvantaged, or suffer inequality, when they make decisions about how they provide their services. This is in addition to their legal obligation not to discriminate against protected groups, including women, under the Equality Act. We speak to BBC political correspondent Alex Forsyth. The Archers on BBC Radio 4 has been exploring cancer genetics. When Pip discovered a lump in her breast, old fears were revived for her mother Ruth, who survived breast cancer many years earlier. BRCA genes can lead to a higher chance of developing cancer and Pip begins to worry she may be at risk. Felicity Finch, who plays Ruth Archer, joins Nuala along with Julian Barwell, Professor in Genomic Medicine at The University of Leicester.Sudanese-Australian writer Yassmin Abdel-Magied has written her first novel for adults, At Sea. It's set on an oil rig in the middle of international waters, and is so detailed on the lifestyle and logistics that it's perhaps no surprise that Yassmin worked in the industry after studying mechanical engineering at university. She joins Nuala.

After conducting pregnancy tests on the Brookfield cows Alistair chats to David about the poisonous atmosphere at Home Farm, wondering if David might be able to soften Brian's hardline stance. When David mentions trade stand bookings for the Borchester Show are right down Alistair says a client complained about the payment system on the showground last year. David says he'll investigate, before Alistair chases up numbers for the minibus trip to the Women's T20 World Cup on Friday. Amber's pleased by the uptick in social media engagement for the Borchester Show since she took over strategy from George. The money they earn will help cover the cost of all the baby gear they need. David calls, asking Amber to use her contacts at Farm Supplies to find out why trade stand bookings are down, and to target local businesses with positive messaging. Later, Amber and George are able to confirm the slow wi-fi led to payment difficulties last year, putting businesses off booking again. David vows to try and fix it. Stella enthuses about wedding preparations to distracted Pip, who's waiting for the call from a genetic counsellor. After several false alarms Pip finally speaks to the counsellor, then later tells Stella about the issues they covered, including potential risks to having children in future. Stella suggests focusing on the next step and Pip says she's agreed to take the private BRCA gene variant test. It's hard, but once Pip's done the test, they'll know for sure without having to wait for Ruth's NHS referral, which she hasn't even asked for yet.

Could a New York court really declare 3.8 million dormant Bitcoin — including coins linked to Satoshi — as "abandoned property"? This week the Bitcoin Policy Institute team dissects an anonymous lawsuit built on an obscure lost-and-found statute, and explains why the legal theory is weak but the precedent could be devastating. Ken Egan, Zack Shapiro, and Zack Cohen also cover the Blockchain Regulatory Certainty Act (BRCA) after its Senate Banking Committee markup and the surprising opposition from sheriffs' associations. Alex Thorn Article about New York case attempting to seize bitcoin:https://www.galaxy.com/insights/research/satoshi-bitcoin-salomon-brothers-patoshi-abandoned-property-new-york-noah-doe-lawsuitForeign Influence on AIhttps://www.btcpolicy.org/articles/foreign-influence-in-the-campaign-against-american-ai

On this episode of CoinDesk's The Policy Protocol, hosts Rebecca Rettig and Renato Mariotti open with the rising uncertainty around CLARITY's path through the Senate before sitting down with House Majority Whip Tom Emmer (R-MN), who argues the bill is the sixth iteration of crypto market structure legislation, defends the Blockchain Regulatory Certainty Act (BRCA) against law-enforcement concerns, and frames the U.S. push to become the "crypto capital of the world" as a fundamentally bipartisan, 21st-century-finance issue. Plus, Rebecca and Renato debrief on the new White House executive order on integrating digital assets into traditional financial systems, the limits of building business strategy on non-durable guidance, and name Senator Angela Alsobrooks (D-MD) as their Person of the Week for her bipartisan work getting CLARITY out of Senate Banking 15-9. - 00:00 "Crypto Is Not a Partisan Issue" 00:18 Welcome to The Policy Protocol 01:13 Hot Topic: Is Crypto Better Off Than Under Biden? 03:35 Crypto's TradFi Era 04:32 House Majority Whip Tom Emmer Joins 06:54 Beyond CLARITY: Genius Act, BRCA, and Crypto Tax 09:28 BRCA vs. Law Enforcement: The "Red Herring" 11:30 What If CLARITY Doesn't Pass This Congress? 13:54 Off-Committee Senators and CFTC Authority 18:38 Why Executive Orders Aren't Enough 21:17 Watching for the SEC's Innovation Exemption 22:29 Person of the Week: Sen. Angela Alsobrooks

On April 29th, the US Senate hosted a panel on the "existential threat" of AI and two of the four panelists worked for the Chinese government. One month earlier, Bernie Sanders and AOC introduced legislation imposing a federal moratorium on American AI data centers. On Bitcoin Policy Hour EP 38, Zack Cohen, Ken Egan, and Zack Shapiro unpack a new Bitcoin Policy Institute report by Sam Lyman exposing the CCP influence operation steering US AI policy. They also cover the Clarity Act vote in Senate Banking, the BRCA fight, and the Digital Asset Parity Act. Sam Lyman's BPI Report: https://www.btcpolicy.org/articles/foreign-influence-in-the-campaign-against-american-ai

Most people think breast cancer treatment ends when the tumor is gone. Science says that's where the real damage often begins, and the woman making that argument was diagnosed at 28, lost her mother to ovarian cancer the same year, and turned her own dismissal by the medical system into a specialization that now treats women nobody else will touch. In this episode, I sit down with Dr. Corinne Menn Board Certified OBGYN, breast cancer survivor, and one of the few specialists in the world treating menopause in cancer survivors. We break down why 80% of women diagnosed with breast cancer have no strong family history, why tamoxifen and aromatase inhibitors quietly devastate brain, bone, and sexual health, and why telling a woman with severe vaginal atrophy to use coconut oil is not evidence-based medicine. Dr. Corinne also opens up about her own diagnosis, her premature menopause at 28, the truth about hormone replacement therapy after breast cancer, and the BRCA, ApoE4, and surgical menopause snowball nobody is putting together for patients. This conversation will completely change how you think about breast cancer, menopause, and the women's health crisis hiding in plain sight. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Why Nobody Is Coming to Save Breast Cancer Survivors 01:05 Karin's Origin Story: Diagnosed at 28, Losing Her Mom, and Premature Menopause 03:06 The 85% Cure Rate Lie: Why Survival Comes at a Brutal Cost 06:13 Breast Cancer Is Not One Disease: Why 80% Have No Family History 08:14 BRCA1, BRCA2, and the Genetic Mutations Most Women Never Get Tested For 13:14 Karin's Own Genetic Test Story and Why 23andMe Is Not Enough 15:07 BRCA1 vs BRCA2: Age of Onset and When to Remove Ovaries 17:30 The Biology of Estrogen: Why Estrogen Does Not Cause Breast Cancer 23:40 Birth Control, Breastfeeding, and the Real Risk Factors 26:17 Alcohol, Inflammation, and the Toxins Driving Cancer Rates 27:46 Tamoxifen Explained: What It Does to Your Brain, Bones, and Body 34:23 Aromatase Inhibitors: Putting Your Estrogen in the Basement 37:15 Where Women Go When No Doctor Will Help Them 41:17 Oophorectomy, Early Menopause, and the 6 to 12% of Women Affected 44:26 Why Black Women Face the Highest Risk and the Least Care 46:20 The ApoE4, BRCA, and Surgical Menopause Snowball 48:02 Coconut Oil Is Not Medicine: The Vaginal Estrogen Truth 50:35 HRT Denial and the Myths Keeping Women From Treatment 51:13 Who Owns the Breast Cancer Survivor After Treatment Ends 54:18 Why the System Fails: Reimbursement, Resources, and Survivorship Gaps 01:00:07 Can You Be on Tamoxifen and Hormone Replacement Therapy? 01:03:26 Three Neurologists, One Tau Test, and the Dementia Dismissal 01:06:26 Positive Stories: Women Who Took Back Their Health and Won 01:09:16 The One Wish: Valuing Ovarian Function Beyond Reproduction _______ Thank you to our sponsors KetoneIQ: https://ketone.com/NEURO for 30% OFF DailyBasis: https://www.dailybasislife.com/NEURO for 50% off first month IQBARS: https://www.eatiqbar.com/ Biologica: https://biologica.com/NEURO Up to 32% off first subscription order Cure Hydration: https://www.curehydration.com/ Use code NEURO gets 20% off Honey Love: https://www.honeylove.com/NEURO Save 20% Off Honeylove #honeylovepod _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

Leonard asks Ben if Ruth has decided whether to be tested for the BRCA gene variant. Ben's still annoyed with Josh for not wanting to know, an attitude he thinks is typically selfish. Following yesterday's chat with Alan, Leonard considers how lucky he is being retired, and that life seems more stressful these days. Ben agrees - the surgery has so many people saying they're struggling. He hopes the mental health initiatives he's trying to set up with Azra will help address these pressures. Adam has spoken to Ruairi, who agrees that Brian must be made to let go of the business. Ian's surprised Ruairi agreed, considering the George attack cover–up, but Adam insists it's for Brian's own good. Brian's out of his depth, plus his dinosaur attitudes and lack of futureproofing are no good for Home Farm. It needs to be addressed at the partnership meeting. Kate's horrified by the idea of caravan storage and agrees with Adam. Ian is concerned that the family are being misled by inaccurate dementia speculation, but Adam feels he has no choice. Having invited Alice to dinner, Adam pleads with her to help form a united front against Brian. Alice wants more time though - Brian really doesn't think he's got dementia. Instead of rocking the boat, can't they just persuade him to get some kind of cognitive fitness test? Frustrated, Adam insists the clock is ticking – he sees Brian floundering badly and if they don't act quickly, Home Farm is going to fail.