Podcasts about brca

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this episode, Peter explores the critical topic of breast cancer screening, examining why thousands of women continue to die from breast cancer each year despite the availability of effective screening tools. He explains the strengths and limitations of current screening strategies, reviews the recommendations from major medical organizations, and discusses why screening guidance can often seem confusing or contradictory. Peter outlines a practical framework for understanding breast cancer risk and personalizing screening decisions, including when to begin screening, how frequently to screen, and which imaging modalities may be most appropriate based on an individual's risk profile. Throughout the episode, he emphasizes that while population-based guidelines provide an important foundation, optimizing outcomes requires a more personalized approach aimed at helping women make informed screening decisions that can improve the chances of early detection and successful treatment. We discuss: Why women still die from breast cancer: the benefits of screening, the problem of under-screening, and the need for risk-based screening strategies [1:45]; Current screening recommendations, why they differ between organizations, and the importance of personalized screening decisions [6:30]; A framework for personalizing screening [8:45]; Assessing baseline breast cancer risk: genetics, family history, breast density, lifestyle factors, and the role of risk calculators in personalized screening [9:30]; Balancing cancer detection and false positives: how breast cancer risk influences screening intensity and imaging choices [17:45]; Mammography as the foundation of breast cancer screening: detecting ductal carcinoma in situ (DCIS) and the advantages of 3D versus 2D mammography [21:00]; MRI for high-risk women: the benefits of supplemental screening, abbreviated MRI, and the emerging role of contrast-enhanced mammography [23:00]; The role of ultrasound: supplemental cancer detection, diagnostic evaluation, and limitations compared with mammography and MRI [26:00]; Choosing the right breast cancer screening strategy: imaging modality selection, screening hierarchies, and the importance of imaging center quality [28:00]; How often should you screen for breast cancer? [30:15]; At what age should you start screening? [37:30]; Breast cancer in younger women: aggressive tumor biology, BRCA-related risk, breast density, and individualized decisions about when to begin screening [41:45]; Inflammatory breast cancer, the limitations of screening mammography for symptomatic disease, and the importance of promptly evaluating new breast symptoms in both women and men [44:45]; From risk assessment to personalized screening: a practical framework for reducing breast cancer mortality through earlier and more effective detection [46:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

CoinDesk's The Policy Protocol hosts Rebecca Rettig and Renato Mariotti unpack the CFTC's 267-page proposed rule-making around prediction markets and event contracts, plus the letter from crypto CEOs backing the BRCA. And, a debate between John Lothian and Udesh Jha, Head of Exchange Analytics at Kalshi, over whether crypto perpetuals are properly classified as futures or swaps. - Read more from Ari Redbord about the mixer indictment under 1956: https://www.linkedin.com/posts/ari-redbord_in-the-midst-of-debate-around-clarity-activity-7470924721635794944-8yUy?utm_source=share&utm_medium=member_ios&rcm=ACoAADHl20UBUd56sB8eTJ0w5gv3WIBQo2eJ6f0 - Timecodes: 00:00 Welcome to The Policy Protocol 01:10 CFTC's 267-Page Prediction Markets Rule 03:10 60+ CEOs Back the BRCA 05:30 The Perpetuals Debate 07:43 John Lothian's Case: Do Perpetuals Look Like Swaps? 09:45 Kalshi's Udesh Jha on Funding Rates and Cost of Carry 12:43 Would Swap Status Shut Out Retail? 16:45 Is Kalshi Making the Rules Up? 19:25 John's Closing: Market Manipulation Concerns 20:46 Udesh's Closing: 'Regulation First' 23:29 Person of the Week: State Regulators 23:38 Illinois' Digital Asset Trading Tax 24:20 NY DFS Aligns With Genius

The NNRC News Show is back with another episode! Max and Lefty explore some breaking industry news as Javier Garcia gets appointed as IFMAR section chairman, the biggest races in the past few weeks such as the Jconcepts ONS at Adrenaline and ETS at Apeldoorn as well as the coolest new releases in the RC Market! Time Stamps: 0:00 - Intro & Catchup 8:52 - Industry News  9:40 - Javier Garcia Interim IC Director at IFMAR  24:41 -Rick Howhart Departs from AR after 19 years  29:28 - Race Results  30:33 - JBRL  33:05 - Brca 1/10 the Nats rd #3 34:41 -Spanish Nats RD #3  38:25 - ONS RD #2 44:50 - GT Euros 51:22 - Italian Race  57:48- Barrufolo Wins Kyosho Masters  1:00:23 - ETS RD #1 1:17:29 - New Releases - AE Drops1/8th Platform  1:34:56 - Sparko F8 SE  1:36:16 - AE FTE RC10 Truck  1:40:34 - Avalon TC Body  2:11:02 - 3d Printed nitro pipe Manifold?  2:15:10 - R1 Wurks Titanium Driveshafts  2:18:24 -TLR RPP is Back  2:21:04 -  David Ronnefalk Buys Latera Racing  2:25:26 - Max Rear vs Mid Motor Rebuttal  2:38:27 - Conclusion 

For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:https://www.mycme.com/courses/the-evolving-role-of-antibody-drug-conjugates-in-metastatic-triple-negative-breast-cancer-10800SummaryThis CME/CE-certified podcast will provide multidisciplinary clinicians with an evidence-based update on the evolving role of TROP2-directed antibody-drug conjugates (ADCs) in the frontline treatment of metastatic triple-negative breast cancer. A medical and an ocular oncology specialist review the latest efficacy and safety data from pivotal clinical trials evaluating ADCs, their integration into contemporary treatment algorithms, and guideline recommendations based on PD-L1 status, BRCA mutation status, and immunotherapy eligibility. Learners will explore key factors influencing treatment selection, compare the benefits and limitations of more established therapeutic options, and examine practical strategies for preventing, recognizing, and managing ADC-associated toxicities. Special emphasis will be placed on multidisciplinary approaches to the management of ocular adverse events and other clinically significant toxicities to optimize patient outcomes and support safe implementation of these therapies in clinical practice.Learning ObjectivesEvaluate the current and emerging clinical evidence surrounding the use of trophoblast cell-surface antigen 2 (TROP2)-directed antibody-drug conjugates (ADCs) in the first-line treatment of metastatic triple-negative breast cancer (TNBC)Integrate TROP2-directed ADCs into frontline treatment regimens for metastatic TNBC based on the latest clinical evidence, guidelines, and patient- and tumor-specific factorsApply multidisciplinary and patient-centric strategies for the prevention, recognition, and management of toxicities associated with the use of TROP2-directed ADCs in patients with metastatic TNBCThis activity is accredited for CME/CE CreditThe National Association for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.The National Association for Continuing Education designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.The National Association for Continuing Education is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 121222. This activity is approved for 0.50 contact hours (which includes 0.50 hours of pharmacology). For additional information about the accreditation of this program, please contact NACE at info@naceonline.com.Faculty and Moderator Aditya Bardia, MDProgram Director, Breast Medical Oncology, UCLAProfessor of Medicine, UCLALos Angeles, CADr. Bardia has disclosed the following financial relationships:Consultant: Alyssum, AstraZeneca/Daiichi, BMS, Eli Lilly, Genentech, Gilead, Menarini, Merck, Novartis, Pfizer, VyomeAdvisor/Advisory Board: Alyssum, AstraZeneca/Daiichi, Eli Lilly, Genentech, Gilead, Menarini, Merck, Novartis, Pfizer, VyomeContracted Research: AstraZeneca/Daiichi, Eli Lilly, Genentech, Gilead, Menarini, Merck, Novartis, PfizerStock options: Vyome (immuno-inflammatory and rare diseases)All of his consultant, advisor/advisory board, and contracted research disclosures are related to cancer.Maura Di Nicola, MDAssistant Professor of OphthalmologyBascom Palmer Eye InstituteMedical Director of Imaging and EchographyBascom Palmer Eye InstituteMiami, FLDr. Di Nicola has disclosed the following financial relationships:Consultant: AbbVie (ophthalmology), SpringWorks Therapeutics (oncology)Advisor/Advisory Board: AbbVie (ophthalmology)Research Grant: Castle Biosciences (ocular oncology)Please review additional planner disclosures here.Disclosure of Commercial SupportThis educational activity is supported by a medical education grant from AstraZeneca Pharmaceuticals and a medical education grant from Daiichi Sankyo, Inc.Please visit  http://naceonline.com to engage in more live and on demand CME/CE content.

The Women's T20 cricket world cup begins on Friday. Nuala McGovern talks to Clare Connor, former England women's captain, now the outgoing Managing Director of England Women. Over her 18 years in the job Clare has overseen the professionalisation of the women's game as well as a big boost in the grassroots participation.Conservative Party leader Kemi Badenoch is arguing that the Public Sector Equality Duty should be scrapped. This duty exists to make public authorities think about things like discrimination and the needs of people who are disadvantaged, or suffer inequality, when they make decisions about how they provide their services. This is in addition to their legal obligation not to discriminate against protected groups, including women, under the Equality Act. We speak to BBC political correspondent Alex Forsyth. The Archers on BBC Radio 4 has been exploring cancer genetics. When Pip discovered a lump in her breast, old fears were revived for her mother Ruth, who survived breast cancer many years earlier. BRCA genes can lead to a higher chance of developing cancer and Pip begins to worry she may be at risk. Felicity Finch, who plays Ruth Archer, joins Nuala along with Julian Barwell, Professor in Genomic Medicine at The University of Leicester.Sudanese-Australian writer Yassmin Abdel-Magied has written her first novel for adults, At Sea. It's set on an oil rig in the middle of international waters, and is so detailed on the lifestyle and logistics that it's perhaps no surprise that Yassmin worked in the industry after studying mechanical engineering at university. She joins Nuala.

After conducting pregnancy tests on the Brookfield cows Alistair chats to David about the poisonous atmosphere at Home Farm, wondering if David might be able to soften Brian's hardline stance. When David mentions trade stand bookings for the Borchester Show are right down Alistair says a client complained about the payment system on the showground last year. David says he'll investigate, before Alistair chases up numbers for the minibus trip to the Women's T20 World Cup on Friday. Amber's pleased by the uptick in social media engagement for the Borchester Show since she took over strategy from George. The money they earn will help cover the cost of all the baby gear they need. David calls, asking Amber to use her contacts at Farm Supplies to find out why trade stand bookings are down, and to target local businesses with positive messaging. Later, Amber and George are able to confirm the slow wi-fi led to payment difficulties last year, putting businesses off booking again. David vows to try and fix it. Stella enthuses about wedding preparations to distracted Pip, who's waiting for the call from a genetic counsellor. After several false alarms Pip finally speaks to the counsellor, then later tells Stella about the issues they covered, including potential risks to having children in future. Stella suggests focusing on the next step and Pip says she's agreed to take the private BRCA gene variant test. It's hard, but once Pip's done the test, they'll know for sure without having to wait for Ruth's NHS referral, which she hasn't even asked for yet.

Could a New York court really declare 3.8 million dormant Bitcoin — including coins linked to Satoshi — as "abandoned property"? This week the Bitcoin Policy Institute team dissects an anonymous lawsuit built on an obscure lost-and-found statute, and explains why the legal theory is weak but the precedent could be devastating. Ken Egan, Zack Shapiro, and Zack Cohen also cover the Blockchain Regulatory Certainty Act (BRCA) after its Senate Banking Committee markup and the surprising opposition from sheriffs' associations. Alex Thorn Article about New York case attempting to seize bitcoin:https://www.galaxy.com/insights/research/satoshi-bitcoin-salomon-brothers-patoshi-abandoned-property-new-york-noah-doe-lawsuitForeign Influence on AIhttps://www.btcpolicy.org/articles/foreign-influence-in-the-campaign-against-american-ai

General Principles and Triple AssessmentThe foundation of breast cancer diagnosis is the Triple Assessment protocol, which includes clinical examination, imaging, and pathological assessment.Diagnostic accuracy reaches 99.9% when all three modalities of the Triple Assessment align.Imaging choices are age-dependent, with ultrasound preferred for women under 35 and mammography for those over 35.Core needle biopsy is superior to fine-needle aspiration because it differentiates between in situ and invasive disease and allows for hormone receptor and HER2 status testing.The majority of breast cancers are sporadic, accounting for 65% to 75% of cases, while hereditary factors like BRCA 1 and 2 mutations contribute to 5% to 10%.Classification and Clinical PresentationBreast cancer is classified into non-invasive types, such as Ductal Carcinoma In Situ (DCIS), and invasive types, of which invasive ductal carcinoma is the most common.The most frequent clinical presentation is a hard, irregular, non-tender, and poorly mobile palpable mass.Approximately 60% of breast tumors are located in the upper outer quadrant.Advanced clinical features include skin dimpling from Cooper's ligament involvement, nipple retraction, and peau d'orange due to lymphatic obstruction.Paget's disease of the nipple presents as a unilateral, eczema-like ulceration and is often associated with an underlying malignancy.Staging and PrognosisClinical staging follows the TNM system, assessing the primary tumor size (T), regional lymph node involvement (N), and distant metastasis (M).Stage I and II are classified as early breast cancer, Stage III as locally advanced, and Stage IV as metastatic disease.The Nottingham Prognostic Index (NPI) calculates prognosis based on tumor size, nodal status, and histological grade.Five-year survival rates decrease significantly with advancing stage, from 90% in Stage I to 20% in Stage IV.Management of DCIS and Early Breast Cancer (Stages I & II)DCIS is a non-invasive cancer confined by an intact basement membrane that requires treatment to prevent progression to invasive disease.Standard treatment for DCIS is breast-conserving surgery (BCS) followed by radiation, or a mastectomy if the disease is widespread.For early invasive cancer, BCS followed by radiation is oncologically equivalent to a total mastectomy.Sentinel lymph node biopsy (SLNB) is the standard for staging the axilla in clinically node-negative patients to avoid the morbidity of full axillary dissection.Adjuvant systemic therapy, including endocrine therapy for ER-positive tumors and anti-HER2 therapy for HER2-positive tumors, is dictated by the tumor's biological profile.Management of Locally Advanced (Stage III) and Metastatic Cancer (Stage IV)Locally advanced breast cancer is treated with neoadjuvant systemic therapy as the first step to shrink the tumor and treat micrometastatic disease before surgery.Following neoadjuvant therapy, axillary lymph node dissection is mandatory if nodes were positive at presentation, regardless of the clinical response.Post-mastectomy radiation is indicated for tumors larger than 5 cm or when four or more axillary nodes are positive.Metastatic (Stage IV) disease is treatable but generally incurable, focusing on palliation and maintaining quality of life.Systemic therapy is the mainstay for Stage IV, and routine surgery on the primary tumor is avoided unless needed for local symptom control.Bone is the most common site of metastasis, requiring management with bone-modifying agents like bisphosphonates to prevent skeletal complicatio

How This Is Building Me, hosted by world-renowned oncologist D. Ross Camidge, MD, PhD, is a podcast focused on the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life's experiences.In this episode, Dr Camidge sat down with Karen L. Reckamp, MD, director of Medical Oncology, associate director of Clinical Research, and the medical oncology director of the Lung Institute at Cedars Sinai in Los Angeles, California.Drs Camidge and Reckamp discussed Dr Reckamp's journey as an oncology specialist and now a caregiver for her husband, who has cancer. Reckamp's career was inspired by her family's history with BRCA-related cancers. She pursued an academic path that eventually led her to Los Angeles, where she became a leader in thoracic oncology during an era of genomic breakthroughs.In late 2024, her husband, a fellow oncologist, was diagnosed with pancreatic cancer shortly after a clear annual scan. Reckamp described the jarring transition of receiving the diagnosis and the ensuing emotions balanced with medical pragmatism. Bob underwent intensive treatments that have affected his physical health and daily life.Reckamp offered a candid look at the dual role of a physician-caregiver. She continues to work, however, her husband's cancer diagnosis has changed her practice. Now, she is more sensitive to chemotherapy toxicities in her patients that she might have previously minimized. She also highlighted the invisible load of caregivers who must manage their own emotions and remain available for patient needs.Ultimately, Reckamp emphasized the necessity of a support network, crediting their long-time nanny and overall community with maintaining her family's stability. By allowing different people to hold different pieces of the emotional burden, Reckamp shared that her family is finding a way to move forward amidst the uncertainty of this cancer diagnosis.

O episódio 43 do EVA CAST, o podcast do Grupo Brasileiro de Tumores Ginecológicos, aborda como a oncologia de precisão vem transformando, na prática, o tratamento do câncer de ovário. Em um cenário marcado pelo avanço da biologia molecular, o episódio discute como testes genéticos, biomarcadores, inibidores de PARP, imunoterapia e novas terapias-alvo passaram a redefinir estratégias terapêuticas e ampliar as possibilidades de cuidado personalizado para as pacientes. Participam da conversa Mariana Scaranti, oncologista clínica da Rede Américas e diretora de pesquisa do EVA; Noele Gomes, oncologista clínica do Hospital São Domingos, no Maranhão; e Andreia Cristina de Melo, oncologista clínica da Oncologia Américas e chefe da Divisão de Pesquisa Clínica e Desenvolvimento Tecnológico do INCA. Ao longo do episódio, as especialistas discutem como a caracterização molecular dos tumores ovarianos mudou a prática clínica nos últimos anos e passou a orientar desde a escolha da manutenção até o sequenciamento terapêutico em doença recorrente. Entre os principais pontos abordados estão os biomarcadores que atualmente impactam a tomada de decisão terapêutica, como BRCA1 e BRCA2, deficiência de recombinação homóloga (HRD), PD-L1, HER2, receptor de folato alfa e deficiência de mismatch repair. O episódio também detalha o momento ideal para realização de testes genéticos e moleculares e explica como essas informações passaram a influenciar diretamente a seleção de terapias-alvo e o manejo individualizado das pacientes. A conversa explora ainda os avanços recentes em diferentes subtipos da doença, incluindo o carcinoma seroso de baixo grau, com destaque para estudos envolvendo hormonioterapia, inibidores de CDK4/6 e drogas direcionadas à via MAP-quinase. Também são discutidos os resultados mais recentes apresentados em congressos internacionais, como estudos com anticorpos droga-conjugados, imunoterapia e novas estratégias para pacientes com doença resistente à platina. Outro eixo importante do episódio é o impacto dos inibidores de PARP na história natural do câncer de ovário, especialmente em pacientes com mutação em BRCA ou HRD positivo, além da discussão sobre como a doença começa a caminhar para um modelo de cuidado mais próximo ao de uma condição crônica, com múltiplas linhas de tratamento personalizadas ao longo do tempo. As especialistas também analisam os desafios de acesso no Brasil e em outros países de baixa e média renda, incluindo desigualdades entre sistemas público e privado e dificuldades na incorporação de testes e terapias inovadoras. Como mensagem final, as convidadas reforçam que a oncologia de precisão já deixou de ser uma perspectiva futura e passou a fazer parte do presente do tratamento do câncer de ovário, embora ainda existam barreiras importantes para garantir acesso amplo e equitativo às pacientes.

On this episode of CoinDesk's The Policy Protocol, hosts Rebecca Rettig and Renato Mariotti open with the rising uncertainty around CLARITY's path through the Senate before sitting down with House Majority Whip Tom Emmer (R-MN), who argues the bill is the sixth iteration of crypto market structure legislation, defends the Blockchain Regulatory Certainty Act (BRCA) against law-enforcement concerns, and frames the U.S. push to become the "crypto capital of the world" as a fundamentally bipartisan, 21st-century-finance issue. Plus, Rebecca and Renato debrief on the new White House executive order on integrating digital assets into traditional financial systems, the limits of building business strategy on non-durable guidance, and name Senator Angela Alsobrooks (D-MD) as their Person of the Week for her bipartisan work getting CLARITY out of Senate Banking 15-9. - 00:00 "Crypto Is Not a Partisan Issue" 00:18 Welcome to The Policy Protocol 01:13 Hot Topic: Is Crypto Better Off Than Under Biden? 03:35 Crypto's TradFi Era 04:32 House Majority Whip Tom Emmer Joins 06:54 Beyond CLARITY: Genius Act, BRCA, and Crypto Tax 09:28 BRCA vs. Law Enforcement: The "Red Herring" 11:30 What If CLARITY Doesn't Pass This Congress? 13:54 Off-Committee Senators and CFTC Authority 18:38 Why Executive Orders Aren't Enough 21:17 Watching for the SEC's Innovation Exemption 22:29 Person of the Week: Sen. Angela Alsobrooks

On April 29th, the US Senate hosted a panel on the "existential threat" of AI and two of the four panelists worked for the Chinese government. One month earlier, Bernie Sanders and AOC introduced legislation imposing a federal moratorium on American AI data centers. On Bitcoin Policy Hour EP 38, Zack Cohen, Ken Egan, and Zack Shapiro unpack a new Bitcoin Policy Institute report by Sam Lyman exposing the CCP influence operation steering US AI policy. They also cover the Clarity Act vote in Senate Banking, the BRCA fight, and the Digital Asset Parity Act. Sam Lyman's BPI Report: https://www.btcpolicy.org/articles/foreign-influence-in-the-campaign-against-american-ai

Around one out of every ten women will be diagnosed with breast cancer during their lifetime. But it wasn't the news Lindsay Bartels was expecting to get at the age of twenty-six. Faced with her own mortality and the impact cancer treatment could have on her fertility, Lindsay had to deal with yet another revelation. She tested positive for the BRCA 1 gene meaning her risk of cancer was higher and this could be passed onto any children she might have. Lindsay, who shares her experience in her memoir Imogen in Waiting, speaks to Mihingarangi about the choices she had to make - including one that wasn't as clear cut as she expected.

AUA2026 Spotlight: PARP-Inhibitor Combination Treatments for the Urologic Care Team CME Available: https://cme.auanet.org/URL/PARP26ONL LEARNING OBJECTIVES: At the conclusion of this CME activity, participants will be able to: 1. Integrate biomarker and genetic testing principles into clinical workflows for patients with metastatic prostate cancer, including when to order testing, how to interpret HRR mutation results (inclusive of BRCA and non-BRCA), and how to address barriers to testing through multidisciplinary coordination. 2. Explain the mechanism of action of PARP inhibitors and the biological and clinical rationale for their use—both as monotherapy and in combination approaches—in the treatment of mPC. 3. Evaluate emerging efficacy and safety data on PARPi combinations, including patient subgroup analyses, sequencing strategies, and the role of combination therapy in different stages of mPC. 4. Apply best practices for side effect monitoring and mitigation in patients receiving PARP inhibitors alone or in combination, leveraging the multidisciplinary team for optimal therapy management and patient quality of life. 5. Implement guideline-concordant care strategies in practice, including genetic testing workflow implementation, coordination among care team members, and patient engagement in shared decision-making and clinical trial enrollment. 5. Utilize current evidence-based guidelines to select and sequence PARP inhibitor therapy for patients with mPC, optimizing oncologic outcomes while individualizing care based on molecular profile and patient-specific factors. ACKNOWLEDGEMENTS: Support provided by independent educational grants from: Astrazeneca Merck & Co., Inc Pfizer, Inc.

Most people think breast cancer treatment ends when the tumor is gone. Science says that's where the real damage often begins, and the woman making that argument was diagnosed at 28, lost her mother to ovarian cancer the same year, and turned her own dismissal by the medical system into a specialization that now treats women nobody else will touch. In this episode, I sit down with Dr. Corinne Menn Board Certified OBGYN, breast cancer survivor, and one of the few specialists in the world treating menopause in cancer survivors. We break down why 80% of women diagnosed with breast cancer have no strong family history, why tamoxifen and aromatase inhibitors quietly devastate brain, bone, and sexual health, and why telling a woman with severe vaginal atrophy to use coconut oil is not evidence-based medicine. Dr. Corinne also opens up about her own diagnosis, her premature menopause at 28, the truth about hormone replacement therapy after breast cancer, and the BRCA, ApoE4, and surgical menopause snowball nobody is putting together for patients. This conversation will completely change how you think about breast cancer, menopause, and the women's health crisis hiding in plain sight. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Why Nobody Is Coming to Save Breast Cancer Survivors 01:05 Karin's Origin Story: Diagnosed at 28, Losing Her Mom, and Premature Menopause 03:06 The 85% Cure Rate Lie: Why Survival Comes at a Brutal Cost 06:13 Breast Cancer Is Not One Disease: Why 80% Have No Family History 08:14 BRCA1, BRCA2, and the Genetic Mutations Most Women Never Get Tested For 13:14 Karin's Own Genetic Test Story and Why 23andMe Is Not Enough 15:07 BRCA1 vs BRCA2: Age of Onset and When to Remove Ovaries 17:30 The Biology of Estrogen: Why Estrogen Does Not Cause Breast Cancer 23:40 Birth Control, Breastfeeding, and the Real Risk Factors 26:17 Alcohol, Inflammation, and the Toxins Driving Cancer Rates 27:46 Tamoxifen Explained: What It Does to Your Brain, Bones, and Body 34:23 Aromatase Inhibitors: Putting Your Estrogen in the Basement 37:15 Where Women Go When No Doctor Will Help Them 41:17 Oophorectomy, Early Menopause, and the 6 to 12% of Women Affected 44:26 Why Black Women Face the Highest Risk and the Least Care 46:20 The ApoE4, BRCA, and Surgical Menopause Snowball 48:02 Coconut Oil Is Not Medicine: The Vaginal Estrogen Truth 50:35 HRT Denial and the Myths Keeping Women From Treatment 51:13 Who Owns the Breast Cancer Survivor After Treatment Ends 54:18 Why the System Fails: Reimbursement, Resources, and Survivorship Gaps 01:00:07 Can You Be on Tamoxifen and Hormone Replacement Therapy? 01:03:26 Three Neurologists, One Tau Test, and the Dementia Dismissal 01:06:26 Positive Stories: Women Who Took Back Their Health and Won 01:09:16 The One Wish: Valuing Ovarian Function Beyond Reproduction _______ Thank you to our sponsors KetoneIQ: https://ketone.com/NEURO for 30% OFF DailyBasis: https://www.dailybasislife.com/NEURO for 50% off first month IQBARS: https://www.eatiqbar.com/ Biologica: https://biologica.com/NEURO Up to 32% off first subscription order Cure Hydration: https://www.curehydration.com/ Use code NEURO gets 20% off Honey Love: https://www.honeylove.com/NEURO Save 20% Off Honeylove #honeylovepod _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

Leonard asks Ben if Ruth has decided whether to be tested for the BRCA gene variant. Ben's still annoyed with Josh for not wanting to know, an attitude he thinks is typically selfish. Following yesterday's chat with Alan, Leonard considers how lucky he is being retired, and that life seems more stressful these days. Ben agrees - the surgery has so many people saying they're struggling. He hopes the mental health initiatives he's trying to set up with Azra will help address these pressures. Adam has spoken to Ruairi, who agrees that Brian must be made to let go of the business. Ian's surprised Ruairi agreed, considering the George attack cover–up, but Adam insists it's for Brian's own good. Brian's out of his depth, plus his dinosaur attitudes and lack of futureproofing are no good for Home Farm. It needs to be addressed at the partnership meeting. Kate's horrified by the idea of caravan storage and agrees with Adam. Ian is concerned that the family are being misled by inaccurate dementia speculation, but Adam feels he has no choice. Having invited Alice to dinner, Adam pleads with her to help form a united front against Brian. Alice wants more time though - Brian really doesn't think he's got dementia. Instead of rocking the boat, can't they just persuade him to get some kind of cognitive fitness test? Frustrated, Adam insists the clock is ticking – he sees Brian floundering badly and if they don't act quickly, Home Farm is going to fail.

This week's podcast is presented by Michelle and Stephen. We hear from: Katherine - this was one of two calls that we unfortunately missed from last week's podcast - and she is worried about the financial situation at Bridge Farm, she thinks that George needs a business mentor, and she's a bit worried about Brian ; Leigh from Cookham - the other call that slipped through last time - she has thoughts about Ruth and BRCA testing; Lizzie, who has an exciting plot prediction about the Borchester Show; Jo and John who also have a plot prediction about Carol; Tracy from California who has thoughts on Adam's child rearing and George's character; Tracy again, with a plot prediction about blackmail; Katherine again, and she's cross about Ruth and the BRCA testing; Witherspoon, who has thoughts on Pip and her doomscrolling;And finally Lakey Hill Liminal, who has a few words of praise for Brad; We have no emails this week, but as usual we'll hear a roundup of the Dumteedum Facebook group, this week from Lakey Hill Liminal, and the Tweets of the Week from Purple Pumpkin; plus the roundup of this Week in Ambridge, from Suey.Please call into the show using this link:www.speakpipe.com/dumteedum Or send us a voicenote via WhatsApp on: +44 7770 764 896 (07770 764 896 if in the UK) – Open the WhatsApp app, key in the number and click on the microphone icon. Or email us at dumteedum@mail.com How to leave a review on Apple podcasts: https://support.apple.com/en-gb/guide/podcasts/pod5facd9d70/mac***** The Patreon feed for Dumteedum is at www.patreon.com/DumteedumPodcast and the subscription rate is £5.00 per calendar month plus VAT. We recommend that you do not sign up to Patreon using the Patreon app, particularly on iPhones and iPads, as Apple appears to be imposing a 50% surcharge which goes to them, not us. The problem doesn't arise if you go to Patreon through a browser - even if you do this on an iPhone, and once you have signed up, you can still use the Patreon app to listen to the ad-free podcasts.***** Also Sprach Zarathustra licence Creative Commons ► Attribution 3.0 Unported ► CC BY 3.0https://creativecommons.org/licenses/..."You are free to use, remix, transform, and build upon the materialfor any purpose, even commercially. You must give appropriate credit." Conducted byPhilip Milman ► https://pmmusic.pro/ Funded ByLudwig ► / ludwigahgren Schlatt ► / jschlattlive COMPOSED BY / @officialphilman Hosted on Acast. See acast.com/privacy for more information.

47e6GvjL4in5Zy5vVHMb9PQtGXQAcFvWSCQn2fuwDYZoZRk3oFjefr51WBNDGG9EjF1YDavg7pwGDFSAVWC5K42CBcLLv5U OR DONATE HERE: https://www.monerotalk.live/donate GUEST LINKS: https://x.com/orangefren https://x.com/MoneroKon TIMESTAMPS (00:00:00) Monerotopia Intro. (00:13:10) Monerotopia Price Report Segment w/ Bawdy. (00:55:31) Monerotopia Guest Segment w/ OrangeFren. (01:31:08) Monerotopia News Segment w/ Tony. (01:57:45) Monero PC (01:58:13) XMR+BCH Bank run v39.00 (01:58:44) Kyun 3 (01:59:43) HRW post. (02:00:52) 30% off no recurring no KYC VPS this May. (02:04:28) Monero Research Lab. (02:08:19) THORChain incidente update. (02:11:35) The criminalization of privacy. (02:18:29) Monerotopia Viewers on Stage Segment. (02:58:08) Monerotopia Final. NEWS SEGMENT LINKS: Criminilization of privacy: https://x.com/theragetech/status/2054291929647513800?s=46&t=mVZ0A2C1_bwwnAvgawJjlw Fluorine Fermi release: https://x.com/moneroresearchl/status/2054413448969158972?s=46&t=mVZ0A2C1_bwwnAvgawJjlw Creators for Massie: https://x.com/thevinomom/status/2054395332914470939?s=46&t=mVZ0A2C1_bwwnAvgawJjlw Rune to xmr swap: https://x.com/douglastuman/status/2054929883386556812?s=46&t=mVZ0A2C1_bwwnAvgawJjlw Thor incident update: https://x.com/thorchain/status/2055376254514196749?s=46&t=mVZ0A2C1_bwwnAvgawJjlw Warren on tornado cash: https://x.com/theragetech/status/2054951201490239933?s=46&t=mVZ0A2C1_bwwnAvgawJjlw BRCA update: https://x.com/tftc21/status/2055003194426896881?s=46&t=mVZ0A2C1_bwwnAvgawJjlw Xmr post quantum encryption: https://x.com/monero/status/2055359580310241424?s=46&t=mVZ0A2C1_bwwnAvgawJjlw Xmr PC: https://www.reddit.com/r/Monero/s/P89LsAX8i0 15th of May bank run: https://www.reddit.com/r/Monero/s/AOtRDXsRHS Kyun cloud hosting for xmr: https://www.reddit.com/r/Monero/s/5VfdVnZkk3 Will XMR resist the future?: https://www.reddit.com/r/Monero/s/btQ0bePRr2 Servers guru no KYC XMR accepting offer: https://www.reddit.com/r/Monero/s/J2IhseOPNb Logos parallel stories: https://x.com/logos_network/status/2055014173524861155?s=46&t=mVZ0A2C1_bwwnAvgawJjlw European Union surveillance technology being sold to bad actors: https://x.com/hrw/status/2055012107373175201?s=46&t=mVZ0A2C1_bwwnAvgawJjlw SPONSORS: PRICE REPORT: https://exolix.com/ GUEST SEGMENT: https://cakewallet.com & https://monero.com NEWS SEGMENT: https://www.wizardswap.io XMR.BAR: https://xmr.bar Don't forget to SUBSCRIBE! The more subscribers, the more we can help Monero grow! XMRtopia TELEGRAM: https://t.me/monerotopia XMRtopia MATRIX: https://matrix.to/#/%23monerotopia%3Amonero.social ODYSEE: https://bit.ly/3bMaFtE WEBSITE: monerotopia.com CONTACT: monerotopia@protonmail.com MASTADON: @Monerotopia@mastodon.social MONERO.TOWN https://monero.town/u/monerotopia Get Social with us: X: https://twitter.com/monerotopia INSTAGRAM: https://www.instagram.com/monerotopia DOUGLAS: https://twitter.com/douglastuman SUNITA: https://twitter.com/sunchakr TUX: https://twitter.com/tuxpizza

Why are bankers, the AFL-CIO, and law enforcement unions all storming Capitol Hill at the same time? In this episode of the Bitcoin Policy Hour, Zack Cohen sits down with Zack Shapiro and Ken Egan to dissect the CLARITY Act markup, the BRCA developer protection carve-out, and the bizarre coalition trying to kill stablecoin yield. They explain why Tim Scott and the Senate Banking Republicans held the line and what 100+ amendments from Senator Cortez Masto really mean.

Featuring an interview with Dr Wassim Abida, including the following topics: Comparing the clinical relevance of BRCA1 and BRCA2 mutations in prostate cancer (0:00) Relevance and interpretation of LOH (loss of heterozygosity) scores (4:37) Incidence and clinical relevance of PALB2 mutations; role of genetic counseling in the care of patients with prostate cancer (9:33) Key considerations surrounding toxicities associated with PARP inhibitors (15:25) Potential role of saruparib; evolving nomenclature in prostate cancer (22:36) Approach to newly diagnosed metastatic prostate cancer (26:16) Clinical relevance of PSMA-targeted PET imaging results (29:49) Case: A man in his mid 70s with metastatic castration-resistant prostate cancer (mCRPC) and a deleterious BRCA alteration receives olaparib/abiraterone/prednisone upon relapse (32:15) Combining PARP inhibitors with other DNA repair inhibitors; insights on the PSMAddition trial (37:14) Case: A man in his mid 60s with metastatic prostate adenocarcinoma and a BRCA germline mutation receives niraparib/abiraterone/prednisone (43:17) Case: A man in his early 60s with mCRPC and CDK12 mutations receives talazoparib/enzalutamide (45:54) CME information and select publications

This week on One For The Road, Dave is joined by Liberty X star Michelle Heaton for one of the rawest and most brutally honest conversations of the series.From pop fame, red carpets and chart success to addiction, intervention, rehab and rock bottom — Michelle opens up about the reality behind the headlines. She speaks candidly about living with the BRCA gene, undergoing a double mastectomy and hysterectomy, the identity crisis that followed, and how alcohol and cocaine slowly took over her life.Michelle shares the terrifying depths of addiction, drinking vodka at 7am, hiding bottles around the house, pushing away the people she loved most and reaching a point where she genuinely believed she was going to die.Now sober and rebuilding her life one day at a time, Michelle talks about recovery, boundaries, motherhood, self-worth and finding hope after complete chaos.This episode is fearless, heartbreaking, funny in places and deeply inspiring — a conversation about survival, sobriety and what happens when you finally decide you want to live.If you want to connect with me via Instagram, you can find me on the instahandle @Soberdave https://www.instagram.com/soberdave/or via my website https://davidwilsoncoaching.com/Provided below are links for services offering additional help and advice, and links for Michelle.https://www.instagram.com/wonderwomanshel/https://www.wearewithyou.org.uk/https://www.drinkaware.co.uk/advice/alcohol-support-serviceshttps://nacoa.org.uk/https://alcoholchange.org.uk/Show producer- Daniella AttanasioInstagram - @Daniellattanasio Hosted on Acast. See acast.com/privacy for more information.

Senate Banking Committee on Thursday advanced long-awaited legislation that would create regulations for cryptocurrencies - a landmark ‌step for the bill which has been bogged down by a dispute between crypto companies and banks. The bill, which was advanced with support from two Democrats, will now proceed to the full Senate, setting the stage for a fierce lobbying fight. ~This episode is sponsored by Tangem~ Tangem ➜ https://bit.ly/TangemPBN Use Code: "PBN" for Additional Discounts! GUEST: Kristin Smith - President at Solana Policy Institute Follow Solana Policy on X ➜ https://x.com/SolanaInstitute Follow Kristen on X ➜ https://x.com/KristinSmith 00:00 Intro 00:10 Sponsor: Tangem 01:30 Markup reaction 02:00 What do you consider as “bipartisan”? 04:30 Gallego & Alsobrooks: are they gonna rugpull us? 06:30 Republican Concessions 08:00 Why is ethics even up for debate? 11:15 Who would be the ethics negotiator? 12:20 Chuck Schumer factor 14:30 Any republican diffracting? 15:40 May Senate vote out of the question? 17:45 Kristin odds of passing 19:40 Why are they touching the BRCA? 23:00 Who to watch? 25:20 Who can challenge Warren? 26:50 In the clear if it passes the Senate? #Crypto #Solana #CLARITY ~CLARITY Next Steps

Lifestyle Medicine & Breast Cancer: Prevention, Treatment Support & Recovery What actually impacts cancer risk—and what helps you get through it? This episode blends expert insight and lived experience to reveal how lifestyle medicine supports prevention, treatment, and healing. In this episode of Her Health Compass, we explore what it truly means to heal through the lenses of resilience, grief, and lifestyle medicine. Yonni and Heather are joined by Dr. Amy Comander, a breast cancer specialist trained in lifestyle medicine, and Britt Aronson, who shares her powerful firsthand experience navigating cancer alongside profound personal loss. Together, they unpack how nutrition, movement, sleep, stress, and mindset can influence not only cancer prevention, but also treatment outcomes and recovery. This conversation bridges science and story—offering both evidence-based insight and lived experience for anyone seeking to better understand their body, their health, and their capacity to heal. Amy Comander, MD, DipABLM, FACLM, MSCP is a breast oncologist and Medical Director of the Mass General Brigham Cancer Institute in Waltham, Director of the Lifestyle Medicine Program at the Mass General Brigham Cancer Institute, and an instructor in medicine at Harvard Medical School. Dr. Comander developed a passion for understanding the biological basis of behavior, and she studied neurobiology and psychology as part of the multidisciplinary Mind, Brain, and Behavior Initiative at Harvard University. She then received her Doctor of Medicine from the Yale University School of Medicine. She completed her internal medicine residency training and Hematology-Oncology fellowship training at Beth Israel Deaconess Medical Center and Harvard Medical School. She is board-certified in internal medicine, hematology, medical oncology, and Lifestyle Medicine. As a breast oncologist, Dr. Comander has witnessed the struggles her patients face during and following completion of primary cancer treatment, and is passionate about improving the overall health and well-being of breast cancer survivors through lifestyle interventions.  In collaboration with Dr. Frates, she launched the PAVING the Path to Wellness Program lifestyle medicine program for breast cancer survivors. She trains other colleagues to run PAVING groups, so that this transformational experience can be offered to a larger group of  cancer survivors.   She has co-authored PAVING Your Path Through Breast Cancer and Beyond,  PAVING the Path to Wellness Manual and Workbook, and PAVING a Path Through Menopause and Beyond. Dr. Comander practices what she preaches, having run marathons, including 12 consecutive Boston Marathons to date, with the goal to improve the lives of those with a diagnosis of cancer.   Dr. Comander was honored to serve as the first oncologist on the Board of Directors of the American College of Lifestyle Medicine. She is proud to serve as Vice President on the Board of the PAVING the Path to Wellness non-profit organization.  She also serves on the Board of the Ellie Fund, a non-profit that provides services and support to women diagnosed with breast cancer in Massachusetts. She is a medical advisor to the non-profit organizations, SurvivingBreastCancer.org and the Tigerlily Foundation.   She has served as a medical advisor to Oneinforty, a non-profit organization dedicated to educating people of Ashkenazi Jewish heritage about the one-in-forty chance of having inherited a BRCA mutation.   Britt Aaronson is a freelance writer and editor based in Los Angeles, where she has lived since 1993. She finds great joy in being a mother to Rayce and Eisley. In her free time, she enjoys yoga, hiking, traveling, and supporting nonprofits including the National Brain Tumor Society, the Hidden Hills Theater Committee, and the Fondle Project. In February 2020, she was diagnosed with Grade 2–3 DCIS breast cancer. Britt underwent seven surgeries—including a double mastectomy, reconstruction, and capsulectomies—and is grateful to now be cancer-free. Deeply appreciative of the technology that led to her diagnosis, she is dedicated to raising awareness and helping redefine conversations around breast health, survivorship, and healing. Find Yonni & Heather here https://www.herhealthcompass.com/

Breast cancer is now the most common cancer affecting people worldwide, with 2.3 million new cases and around 700,000 deaths each year. In India, someone is diagnosed every four minutes, and someone loses her life to breast cancer every eight minutes.But behind these numbers is a question every woman and every family needs to ask: how do we understand breast cancer without fear taking over?To make sense of all this, in this episode of The Wellness Algorithm, I'm joined by Dr P. Raghu Ram,  OBE, Founder Director of KIMS-Ushalakshmi Centre for Breast Diseases and one of India's most respected breast cancer surgeons. Dr Raghu Ram has spent decades advancing breast cancer awareness, early detection and specialist care in India.Together, we talk about lumps, breast pain, nipple discharge, screening after 40, family history, BRCA testing, HRT and the major advances in treatment.

This week we're discussing The Archers, focusing on the episodes from Sunday 10th to Tuesday 12th May.There is a lot to unpack as George and Amber's relationship starts to show worrying cracks, Ruth continues to avoid making a decision about the BRCA test, and Brian manages to annoy almost everyone in Ambridge.We talk about:George and Amber's tense conversations about the babyWhether George is becoming more controllingBrad struggling with Amber, George and DenRuth delaying the BRCA testBrian's treatment of Adam, Ian and StellaIan's new job newsAdam's plans for Home FarmCarol enjoying rewildingRogation Sunday and the return of JakobThe growing number of people who know about the Ruairi secretPlus our regular features:Star of the WeekTwit of the WeekPredictionsThis episode contains spoilers for listeners who are not up to date with this week's episodes of The Archers.Watch, follow & support All About The Archers▶️ Watch on YouTube: All About The Archers☕ Support the podcast: Buy us a coffee

This week we're discussing The Archers, focusing on the episodes from Sunday 3rd to Tuesday 5th May.It's another packed week in Ambridge, with George collecting his money, Brian and Lillian digging themselves even deeper, Ruth facing the reality of BRCA testing, and Carol discovering an unexpected problem in the attic.We talk about:George getting his money from Brian and LillianWhether George has recorded even more evidenceRuth's appointment with Azra and the reality of the BRCA testing processLeonard's wonderful support for Ruth and CarolCarol, Anna and the battle over independenceBats, guano and the chaos at Glebe CottageTom and Natasha's money worriesBrad's sadness over Amber, George and DenPlus our regular features:Star of the WeekTwit of the WeekPredictionsThis episode contains spoilers for listeners who are not up to date with this week's episodes of The Archers.Watch, follow & support All About The Archers▶️ Watch on YouTube: All About The Archers☕ Support the podcast: Buy us a coffee

On this episode of the Mastery Unleashed Podcast, Christie Ruffino interviews Dr. Neja Zupan, who shares a deeply transformative journey shaped by loss, illness, and personal reinvention. After witnessing her mother pass away from cancer with unfulfilled dreams, Dr. Neja made a commitment to live fully and stop postponing her purpose. Later, she faced her own diagnosis of aggressive cancer with only a 5% survival rate, which became a turning point for profound healing and transformation.Rather than following conventional medical paths alone, Dr. Neja explored a holistic approach, developing what she calls “multidimensional intelligence.” This framework integrates physical, emotional, mental, energetic, and spiritual levels to create alignment, vitality, and sustainable success. She applied these principles not only to heal herself but also to transform her business, allowing it to scale internationally with more ease and flow.Central to her teachings are the “Dragon Laws”: cultivating inner peace, thinking beyond conventional limitations, and viewing challenges as opportunities for growth. These principles empower entrepreneurs to break free from burnout, stress, and traditional hustle-driven models.This episode encourages listeners to trust their intuition, embrace transformation, and align their life and business with a deeper purpose for lasting success and fulfillment. ABOUT DR. NEJADr. Neja Zupan is a Global Energy Master and Founder of the Energy Masters Academy, guiding leaders and change makers to understand that inner energy, not strategy, determines how they lead, decide, and create impact.Through practical, body based work rooted in nervous system recalibration, emotional clearing, and multidimensional intelligence, she helps leaders release hidden stress patterns and shift from pressure into presence. When energy aligns, vitality rises, decisions clarify, and results unfold with less force and more resonance.Her work is grounded in lived truth. After being diagnosed with aggressive Stage III+ cancer and carrying the BRCA gene that had taken multiple women in her family, Dr. Neja chose an inner path of energetic recalibration. Within six months, she was cancer free and fundamentally transformed.Today, she empowers leaders to lead from inner authority, embody coherence, and create sustainable impact as an authentic expression of who they are. GET DR. NEJA'S GENEROUS GIFTThe Dragon Laws: Your Business Beyond Logic ToolkitACCESS THIS GIFT AND MANY MORE LINKS SHARED ON THE SHOWwww.linkedin.com/in/drnejazupan/www.instagram.com/dr.neja.zupan.institutewww.facebook.com/drNejaZupanInstitutewww.tiktok.com/@dr_neja_zupan_instituteABOUT OUR SHOWMastery Unleashed is a podcast for success-driven women who want to empower their thoughts, design their dream businesses, and build beautiful lives that are aligned with their destinies—hosted by Bestselling Author and Business Strategist Christie Ruffino.Each episode features today's top influencers and entrepreneurs on the rise as they share empowering stories and ninja tips meant to become the FUEL that will ignite a positive change in YOUR life and the lives of others.ABOUT OUR FREE GIFT VAULTGET THIS GIFT AND MANY MORE HERE: https://masteryunleashedpodcast.com/gift-signup/

This week we're discussing the latest drama in The Archers, focusing on the episodes from Sunday 26th to Tuesday 28th April.There is a lot happening in Ambridge this week, from Kirsty's unexpected baby news to rising tensions at Home Farm, where Adam, Alice and Debbie start questioning Brian's decisions.We talk about:Kirsty's pregnancy and Erik's reactionHelen listening in and offering “support”Brian's latest plans for Home FarmAdam going to Debbie for backupAlice continuing to worry about Brian's behaviourRuth's BRCA test dilemma and what it means for the familyBen supporting Ruth through a difficult conversationGeorge and David's “cyber chatter” for the showHenry winning the cricket logo competitionTom and Natasha's money worriesPlus our regular features:Star of the WeekTwit of the WeekPredictionsThis episode contains spoilers for listeners who are not up to date with this week's episodes of The Archers.Watch, follow & support All About The Archers▶️ Watch on YouTube: All About The Archers☕ Support the podcast: Buy us a coffee

Kristin Crowley has a family history of breast cancer, and a genetic test shows she's BRCA 2 positive. She shares her journey through surgery and the complicated decisions she is making as a middle aged woman who is high risk.

From the Peace Corps in Madagascar to building one of Maine's most recognized oyster catering brands—this episode goes way deeper than oysters. On this episode of The Oyster Ninja Podcast, I sit down with Libby Davis, founder of Lady Shuckers, to talk about the journey behind the shell: • Getting sober and navigating alcohol & drug abuse • Building an oyster farm and catering business from scratch • Her time in the Peace Corps in Madagascar • Her mother's breast cancer journey and genetic predisposition • Facing the BRCA mutation and choosing a double mastectomy • Identity, top surgery, and finding self-worth • The future vision for Lady Shuckers events This is a conversation about resilience, reinvention, and what it really takes to rebuild your life—personally and professionally. If you're into oysters, entrepreneurship, sobriety journeys, or real unfiltered stories… this one's for you.    

This week's podcast is presented by Theo and Stephen. We hear from: · Tim, who has views on Bridge Farm and the Anguses; · Witherspoon, who has been investigating Wednesday's supper faux pas; · Leigh from Cookham, with thoughts about Pip's story; · and finally Witherspoon again, with advice for Ruth on BRCA testing; And we have emails from Chris in Indiana and Gillian in London.As usual we'll hear a roundup of the Dumteedum Facebook group, this week from Michelle, and the Tweets of the Week from Theo, plus the roundup of this Week in Ambridge, from Suey.Please call into the show using this link:www.speakpipe.com/dumteedum Or send us a voicenote via WhatsApp on: +44 7770 764 896 (07770 764 896 if in the UK) – Open the WhatsApp app, key in the number and click on the microphone icon. Or email us at dumteedum@mail.com How to leave a review on Apple podcasts: https://support.apple.com/en-gb/guide/podcasts/pod5facd9d70/mac***** The Patreon feed for Dumteedum is at www.patreon.com/DumteedumPodcast and the subscription rate is £5.00 per calendar month plus VAT. We recommend that you do not sign up to Patreon using the Patreon app, particularly on iPhones and iPads, as Apple appears to be imposing a 50% surcharge which goes to them, not us. The problem doesn't arise if you go to Patreon through a browser - even if you do this on an iPhone, and once you have signed up, you can still use the Patreon app to listen to the ad-free podcasts.***** Also Sprach Zarathustra licence Creative Commons ► Attribution 3.0 Unported ► CC BY 3.0https://creativecommons.org/licenses/..."You are free to use, remix, transform, and build upon the materialfor any purpose, even commercially. You must give appropriate credit." Conducted byPhilip Milman ► https://pmmusic.pro/ Funded ByLudwig ► / ludwigahgren Schlatt ► / jschlattlive COMPOSED BY / @officialphilman Hosted on Acast. See acast.com/privacy for more information.

Guest:Aimee Yowell is a seasoned hairstylist, proud military mom, and the kind of woman who can hold your secrets, your hand, and a pair of scissors all at the same time. A self-proclaimed “hair nerd” at Salon Mystique, she's spent years behind the chair collecting stories as rich and layered as the lives around her. Married for over 30 years after a whirlwind 28-day engagement, she's built a life rooted in faith, family, and fierce loyalty. After losing her mother to breast cancer, Aimee faced her own BRCA diagnosis with courage, choosing preventative surgeries that reflect both strength and deep love for her family. Now “Bossee” to her grandbabies, she's living proof that resilience, humor, and a little bit of sass can carry you through just about anything.Monologue:Deep Eddy Vodka Tasting Room LeavingAnother Icon in Austin Closes-Artemis Reports From The MoonTrump Thanks For A Major Auto ChangeApril Fools GoldRing My Bell For ProsperitySaying what needs to be said and broadcasting straight outta Dripping Springs, Steve Mallett and Michelle Lewis serve up unfiltered, unforgettable conversations with the most interesting folks you've never heard of-yet. From wild small-town stories and Hill Country gossip to sharp takes on real life, they mix humor, heart, and a healthy dose of Texas grit. It's like pulling up a chair at your favorite local bar, where the banter is real, the guests are bold, and nobody's afraid to speak their mind. You'll laugh, you'll think, and you just might see your own story in theirs. New episodes every week...because ordinary people make the best damn stories.Send us Fan MailSupport the showThe Best Realtor in Dripping Springs? The #1 choice is the Mallett Integrity Team, led by Steve Mallett. Local experts and results-driven service-Cedric Mills, Carlisle Kennedy, Maury Boyd, and Michelle Lewis.SouthStar Bank a tradition of full-service community banking for over 100 years. Your neighborhood Bank. Stop by a branch today! The Deep Eddy Vodka Tasting Room in the TX Hill Country just outside Austin, TX, welcomes over 75K visitors annually and sits within the former bottling plant. Family Friendly Fun in the Hill Country. Black Slate Construction /Black Slate Roofing-Locally owned and operated in Austin, TX! Over a decade of experience-their skilled team delivers high-quality construction/roofing and exceptional service.Follow us, leave a review and TELL A FRIEND!AppleInstagramWebsite

Journalist and TV anchor Jenna Wolfe joins therapist Lisa Schuman to share how she built a two‑mom family through fertility treatment and donor conception, came out on the Today Show, navigated a double mastectomy after a BRCA diagnosis, divorced, and is now co‑parenting two daughters. This episode is for anyone using reproductive medicine, or donor conception and worries, “Will my family really be OK?” We walk step‑by‑step through Jenna's story: • Coming out publicly while pregnant and what she was most afraid of • Meeting her wife, deciding to have kids, and whose genetics to use • Fertility treatment in the public eye and choosing a sperm donor • Facing a double mastectomy as a new mom and talking to her kids about it • Divorce, building a healthy co‑parenting relationship, and focusing forward on the children • Small, doable changes that helped her get through fertility, surgery, and starting over If you're building your family with fertility treatment, or donor conception, and want more structured support, you can learn about the Building Your Family education and support platform here: https://familybuilding.net/building-your-family-community/ This episode is sponsored by Seattle Sperm Bank, a donor sperm bank focused on rigorous screening, a wide donor selection, and thoughtful support for LGBTQ+ and solo parents. Learn more here: https://www.seattlespermbank.com/building-your-family/  

Prawie każdy nowotwór wykryty wcześnie jest w 100% wyleczalny. A mimo to 20 lat temu umieraliśmy na to samo, na co umieramy dziś. Dlaczego? Bo ciągle boimy się badań bardziej niż choroby.W tym odcinku rozmawiamy z Magdaleną Palińską — medical expert z upacjenta.pl, dietetykiem klinicznym z ponad 10-letnim doświadczeniem w profilaktyce opartej na medycynie stylu życia i diagnostyce. Bez owijania w bawełnę: jakie badania, jak często, co naprawdę działa, a co to tylko trend w internecie.W odcinku m.in.:dlaczego 90% nowotworów NIE ma podłoża genetycznegolista badań profilaktycznych dla kobiety po 30-tcejak prawidłowo robić samobadanie piersi (i dlaczego większość z nas tego nie robi)badania genetyczne BRCA: czy wynik to od razu wyrokmarkery nowotworowe: kiedy mają sens, a kiedy to niepotrzebny stresnie ma diety na raka: ekspertka obala mit o ketopapierosy, alkohol i styl życia: twarde dane, które trudno zignorować.Magdalena Palińska: https://www.instagram.com/nutripsychiatria/uPacjenta to usługa umożliwiająca wykonanie badań krwi w domu, biurze lub innym wygodnym miejscu – bez kolejek i stresu. Rezerwacja odbywa się online, specjalista przyjeżdża na pobranie, a wyniki są dostępne przez internet.Zamów badania profilaktyczne i skorzystaj z kodu „RANDKA” (ważnego do końca czerwca 2026), aby otrzymać -20% na dowolne badania i pakietyhttps://upacjenta.pl/katalog-badanW kontekście profilaktyki onkologicznej warto również skonsultować z ginekologiem szczepienie przeciwko HPV.subskrybuj kanał: https://www.youtube.com/@natalia_kusiak IG: www.instagram.com/nataliakusiak o mnie: https://www.nataliakusiak.comPatronite: https://patronite.pl/pierwszarandka

Welcome to OncLive On Air®! I'm your host today, Kyle Doherty.OncLive On Air is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.In today's episode, we spoke with David Morris, MD, FACS, and Alan H. Bryce, MD. Dr Morris is the president of Urology Associates, PC, in Nashville, Tennessee. Dr Bryce is a medical oncologist and the chief clinical officer of City of Hope Cancer Center Phoenix in Arizona.In our exclusive interview, Drs Morris and Bryce discussed the clinical implications of the FDA's full approval of rucaparib (Rubraca) for BRCA mutation–associated metastatic castration-resistant prostate cancer (mCRPC), including the notable data that supported the regulatory decision and how this agent fits into the mCRPC treatment paradigm.

The Iran conflict is sending global oil markets into crisis, and the ripple effects could trigger a geopolitical reset with massive implications for Bitcoin. In this episode of Bitcoin Policy Hour, Ken, Zack Shapiro, and host Zack Cohen break down Bitcoin's strategic role in U.S.-China competition, why Lightning Network is becoming the payment standard for AI agents, and the CFTC's precedent-setting no-action letter on non-custodial wallets. They also tackle Basel III's punitive 1,250% capital requirements for banks holding Bitcoin and the fight for a Bitcoin de minimis tax exemption on Capitol Hill. Click here to get 10% off bitcoin 2026 Conference in Las Vegas: https://tickets.b.tc/event/bitcoin-2026?promoCodeTask=apply&promoCodeInput=YT10

When to test, how to prevent, and what you need to know about hereditary gynecologic cancer syndromes. Two USC gynecologic oncologists, Dr. Mona Guo and Dr. Marcia Ciccone, go in-depth in this BackTable OBGYN x Tumor Board crossover episode. --- Get the BackTable app https://www.backtable.com/app --- Timestamps 00:00 - Introduction01:37 - Why Hereditary Cancer Matters04:51 - Family History Red Flags09:01 - Who Should Order Genetic Testing11:32 - Variants and Counseling Pitfalls13:30 - Access and Remote Testing Options19:27 - BRCA1 Positive Patient Walkthrough24:52 - Risk-Reducing Surgeries29:11 - Prevention and Screening Limits32:38 - Why Ovarian Cancer Is Hard34:04 - Combining Breast and Gyn Surgery35:41 - Preop Ultrasound and CA-12536:27 - BRCA Timing and HRT Nuance42:32 - Nonhormonal Menopause Options47:14 - Lynch Syndrome Screening Basics54:22 - Endometrial Biopsy Debate56:43 - Insurance and Coverage Pitfalls59:00 - Fertility Preservation and REI01:01:41 - Cascade Testing01:02:45 - Conclusion --- More about this episode Dr. Guo and Dr. Ciccone discuss how careful family history can identify patients who may benefit from genetic evaluation and highlight key red flags, including a family history of ovarian cancer, breast cancer at age 50 or younger, and metastatic prostate cancer. They explain the role of genetic counseling, including pre- and post-test discussions and how to approach variants of uncertain significance. They then cover BRCA counseling and risk-reduction strategies, including the timing of risk-reducing bilateral salpingo-oophorectomy, ongoing salpingectomy trials, and considerations for hysterectomy. Additionally, they touch on pathology protocols, breast cancer screening, and the potential protective effect of hormonal contraception. The doctors address the limitations of ovarian cancer screening and outline patterns suggestive of Lynch syndrome, such as endometrial cancer occurring alongside gastrointestinal or urinary tract cancers. They review the Lynch workup, including tumor mismatch repair immunohistochemistry and MLH1 hypermethylation testing. Finally, they discuss practical considerations like barriers to access, Medicare coverage challenges, fertility preservation referrals, menopause management, and cascade testing in families, including the timing of testing in children. --- Resources NCCN Guidelines: Detection, Prevention, and Risk Reductionhttps://www.nccn.org/guidelines/category_2

In this episode, I sit down with Arianna Bennett, news anchor at Channel 2 in Reno, Nevada, who is currently going through breast cancer treatment.Arianna shares what it was like to receive her diagnosis, and opens up about almost not getting tested for the BRCA gene. One push from her doctor changed everything, and that decision led to early detection.This conversation is a powerful reminder that knowing your risk matters, and early detection can change outcomes.This is Part 1 of our conversation. In Part 2, we will talk about treatment, chemo, and how Arianna is navigating it all in real time.

Joining the Project Purple Podcast from the Los Angeles area, film and television professional Matt Cassani sits down with host Dino Verrelli to share his experience being diagnosed with pancreatic cancer at just 34 years old, and the long, uncertain road that followed. Matt opens up about the subtle but persistent symptoms he initially dismissed, including stomach discomfort and abdominal pressure, which he was initially told by doctors were diet-related. But when a coworker noticed he looked jaundiced during Mother's Day weekend last year, a visit to urgent care quickly escalated, leading to a shocking Stage 2 pancreatic cancer diagnosis. From there, everything moved quickly. Matt discusses starting chemotherapy at UCLA, undergoing the Whipple procedure, and just recently completing treatment after months of physical and mental challenges. He reflects on what it means to face a disease often labeled as “something older people get,” and how his diagnosis reshaped his understanding of cancer among younger adults. He speaks about carrying the BRCA-2 gene, the importance of genetic awareness, and why advocating for yourself, and knowing when something isn't right, can be life-saving. He also shares how stepping back from constant self-research, focusing on the present, and finding small grounding practices helped protect his mental health. Matt highlights the immense support of the people around him, the value of getting outside and celebrating small victories, and even the simple comforts that helped him cope, like building Legos and giving himself permission to enjoy treats along the way! Looking back, Matt describes pancreatic cancer as a painful, yet profound opportunity for reflection, one that ultimately pushed him to prioritize time with loved ones and approach life with deeper gratitude. Matt welcomes connection and can be found on Instagram at https://www.instagram.com/mattcassani/. Subscribe to the Project Purple Podcast for more stories from the pancreatic cancer community. To learn more or donate to Project Purple's mission of a world without pancreatic cancer, please visit www.projectpurple.org.

Your right to self-custody is being quietly negotiated away. Bipartisan deal-making on the stablecoin bill could gut the BRCA provisions that protect Bitcoin developers and your right to hold your own keys. Meanwhile, the Basel framework's 1,250% risk weight makes it so expensive for banks to hold Bitcoin that none of them will and that may be by design. They also dig into Trini Research's viral 2028 Global Intelligence Crisis report and why mass AI disruption could actually be hyper-bullish for Bitcoin.

Zainab Sow returns to Test Those Breasts to share how daily self-exams helped her find a 1.8 cm lump at 38 and led to a Stage 1 IDC diagnosis. We talk family history without BRCA, survivorship realities, and the side effects many women face after treatment, especially aromatase inhibitors and medically induced menopause. Zainab is a three-time author and founder of Melanin Breast Cancer Alliance, Inc., a nonprofit providing grants to newly diagnosed patients in the U.S. and West Africa, and shares why self-advocacy and boundaries matter.Find Zainab: Instagram @zainab_underscore_air to breast cancer | Heir to Breast CancerHope Beyond Hormones

Approximately 5–10% of all breast cancers are hereditary, and among those, BRCA1 and BRCA2 mutations are responsible for about 60% of cases. Yet, overall, only about 1-2% of all breast cancers in the general population are caused by BRCA mutations. Once childbearing is complete, the NCCN recommends risk-reducing BSO in patients carrying these mutations. But what about the uterus? Since childbearing is complete, and the ovaries are now removed, the sole purpose of the uterus- which is to initiate, nourish, and grow a child -is no longer applicable. Is there a call for inclusion of a hysterectomy at time of risk reducing BSO? This has vast and important implications regarding subsequent hormone therapy. In this episode, which comes from one of our podcast family members, we will dive into the latest data pushing towards the inclusion of hysterectomy at time of prophylactic BSO. It's fascinating data from just last year (2025, in the Journal of the NCI). Listen in for details.1. Kotsopoulos J, Seca M, Gronwald J, et al. Menopausal Hormone Therapy and the Risk of Breast Cancer in Women With a Pathogenic Variant in BRCA1 or BRCA2. Journal of the National Cancer Institute. 2025. 2. Kotsopoulos J, Gronwald J, Karlan BY, et al. Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers. JAMA Oncology. 2018

Two Onc Docs, hosted by Samantha A. Armstrong, MD, and Karine Tawagi, MD, is a podcast dedicated to providing current and future oncologists and hematologists with the knowledge they need to ace their boards and deliver quality patient care. Dr Armstrong is a hematologist/oncologist and assistant professor of clinical medicine at Indiana University Health in Indianapolis. Dr Tawagi is a hematologist/oncologist and assistant professor of clinical medicine at the University of Illinois in Chicago.In this episode, OncLive On Air® partnered with Two Onc Docs to highlight anticipated data from the upcoming 2026 Genitourinary Cancers Symposium, noting presentations to watch at sessions on prostate cancer, bladder cancer, and renal cell carcinoma (RCC).For prostate cancer, the experts revealed that they're looking forward to seeing updated results from the phase 3 PEACE-3 trial (NCT02194842) of enzalutamide (Xtandi) plus radium-223 in patients with metastatic castration-resistant prostate cancer (mCRPC), noting that bone-protecting agents are mandatory for patients receiving radium-223. They also pointed to overall survival data from the phase 2 BRCAAway trial (NCT03012321) of abiraterone (Zytiga) plus prednisone and olaparib (Lynparza) for patients with mCRPC harboring BRCA or ATM alterations. Additionally, they spotlighted the phase 3 PEACE 2 trial (NCT01952223), which explores moving chemotherapy into the localized prostate cancer setting.Regarding bladder cancer, they identified the phase 3 KEYNOTE-B15 trial (NCT04700124) as a potentially practice-changing trial evaluating perioperative enfortumab vedotin-ejfv (Padcev) plus pembrolizumab (Keytruda) in cisplatin-eligible patients with muscle-invasive bladder cancer. They also noted that circulating tumor DNA data are a significant trend, appearing in several clinical trials to guide response-adapted management.For RCC, the hosts highlighted the phase 3 LITESPARK-011 (NCT04586231) and LITESPARK-022 (NCT05239728) trials, which are evaluating the HIF-2α inhibitor belzutifan (Welireg) in different RCC populations. They also emphasized the importance of the CLIMATE study (ACTRN12622000247774) for detecting residual disease in patients with testicular cancer.

In this episode of the IRH Clinician's Corner, guest host (and IRH lead practitioner) Sara Fields sits down with Rachel Frankenthal to do a deep dive into the evolving landscape of menopause and cancer survivorship care, unpacking the profound impact of the FDA's recent removal of the black box warning on hormone replacement therapy. Rachel shares her personal journey from the world of dance to leading-edge women's health, discusses the myths and realities around hormone therapy, and offers actionable strategies for both clinicians and women facing these issues.   In this interview, we discuss:   The historical context of hormone therapy Ongoing misconceptions and fear surrounding hormone therapy Women's Health Initiative (WHI) data and what it shows System-wide educational deficits and resultant misinformation Diet and lifestyle interventions for menopausal women and cancer survivors Early recognition and frequently ordered labs/monitoring The Clinician's Corner is brought to you by the Institute of Restorative Health. Follow us: https://www.instagram.com/instituteofrestorativehealth/   Connect with Rachel Frankenthal Website:  https://www.uclahealth.org/providers/rachel-frankenthal IG: https://www.instagram.com/rachelfrankenthal/?hl=en   Resources for women: The Menopause Society:  https://menopause.org/ The Heather Hirsch Academy: https://heatherhirschacademy.com/  ISHWISH: https://www.isswsh.org/ Jackie Piasta with Monarch Health: https://www.mymonarchhealthco.com/ Alloy and Midi Health (for telehealth options):  https://www.myalloy.com/ and https://www.joinmidi.com/ Timestamps:  00:00 Path to GYN Oncology Career 06:07 Women's Hormone Therapy Controversy 08:02 Estrogen Black Box Warning Debunked 11:49 Reframing Hormone Therapy Perspectives 15:09 Hormone Therapy Benefits and Risks 18:09 "Estrogen's Role in Breast Cancer" 21:16 BRCA, Ovarian Cancer, Hormone Risks 26:28 Advocating with Evidence and Data 29:13 Choosing Menopause-Certified Providers 31:35 Hormone Management and Heather Hirsch 35:24 Individualized Menopause Care and Education 39:44 Mediterranean Diet for Health Optimization 43:35 Prioritize Exercise for Health 46:50 Reeducating Women on Health 50:03 Ovarian Cancer: Know the Symptoms 54:01 Individualized Hormone Therapy Insights 54:51 Advances in Cancer Surveillance 58:10 "Clinician's Corner: Join & Share" Speaker bio:  Rachel Frankenthal is a board-certified and licensed Physician Associate and Menopause Society Certified Practitioner with a Masters in Public Health. She specializes in gynecologic oncology, treating women with gynecologic cancers as well as women at high risk for cancer due to genetic mutations. Rachel has a special passion for menopause and cancer survivorship care. She developed the menopause clinic for cancer survivors at UCLA and has played an integral role in developing the gyn cancer survivorship program. Rachel is a certified yoga and pilates instructor and on faculty at the Heather Hirsch Academy where she teaches a course on hormone therapy for gynecologic cancer survivors.   Keywords:  hormone therapy, menopause, Women's Health Initiative (WHI), gynecologic oncology, breast cancer, estrogen, progesterone, hormone replacement therapy, black box warning, FDA hormone guidelines, cancer survivorship, genetic mutations (BRCA), ovarian cancer, vaginal estrogen, menopause education, symptom management, cancer screening, osteoporosis, bone density, lifestyle interventions, nutrition, Mediterranean diet, exercise, strength training, protein intake, fiber intake, patient advocacy, provider directories, telehealth, lab testing Disclaimer: The views expressed in the IRH Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of the Institute of Restorative Health, LLC. The Institute of Restorative Health, LLC does not specifically endorse or approve of any of the information or opinions expressed in the IRH Clinician's Corner series. The information and opinions expressed in the IRH Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. The Institute of Restorative Health, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the IRH Clinician's Corner series. By viewing or listening to this information, you agree to hold the Institute of Restorative Health, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.  

Hilarious (and True) Hospital Stories | Good To See You | Ep 213Good To See You — episode highlight: Hosts Isaac Abrams, Jen Bartels, and Caitlyn Brodnick deliver raw, hilarious, and painfully honest stories about celebrity run-ins, preventive surgeries, implants, MRSA complications, hospital life, and the messy realities behind healthcare and recovery. The trio blends sharp stand-up wit with candid firsthand accounts — from meeting Matthew Broderick to designing “Coachella nipples,” navigating BRCA testing and preventative mastectomy choices, to implant ruptures, MRSA infection, sepsis, Beverly Hills surgery experiences, medical billing chaos, and auditioning while healing. Expect gut-busting jokes, tender moments, and practical takeaways about body autonomy, friendship, and resilience.Why watch/listen:- Comedy podcast with three working comedians: Isaac, Jen & Caitlyn - Honest BRCA & preventative mastectomy discussion (medical + emotional) - Implant rupture, MRSA & sepsis recovery stories with real details - Hospital anecdotes, aftercare options, and insurance/billing insight - Quirky asides: Merlin the pig, nipple design choices, audition panicTimestamps (major segments)00:00 – 02:00 — Intros & reunion banter (Isaac, Jen, Caitlyn) 02:00 – 10:00 — Matthew Broderick story & early improv jokes 10:00 – 18:30 — BRCA explained & decision for preventative mastectomy 18:30 – 28:00 — Implant design, nipple options & body-image humor 28:00 – 36:00 — Implant ruptures: silicone leakage & surgical scoop talk 36:00 – 47:00 — MRSA explained, infection risks, antibiotic therapy 47:00 – 59:00 — Hospital life: Glendale Adventist, morphine moments, shared rooms 59:00 – 1:02:00 — Insurance, billing nightmares, surgical center vs. hospital care 1:02:00 – 1:10:00 — Aftercare, luxury hotel recovery suites, comic reflections 1:10:00 – End — Rapid-fire anecdotes, sign-off from Isaac, Jen & CaitlynTarget keywords (for title, description, tags)#comedypodcast #goodtoseeyou #funnypodcast - comedy podcast episode- Isaac Abrams- Jen Bartels- Caitlyn Brodnick- BRCA gene- preventive mastectomy- double mastectomy story- breast implant rupture- MRSA infection- sepsis recovery- hospital stories- plastic surgery aftercare- celebrity encounter story- candid comedy podcastSuggested tags (copy to YouTube tags)comedy podcast, standup podcast, Isaac Abrams, Jen Bartels, Caitlyn Brodnick, BRCA, mastectomy, MRSA, sepsis, breast implants, hospital stories, plastic surgery, candid comedy

This week we're joined by Devin Sidell and Amy Byer Shainman from the film Love, Danielle for a powerful conversation about previvorship. The ladies break down what it really means to carry the BRCA gene, who should consider genetic testing, how to get tested, and what steps to take if you receive a positive result. Honest, informative, and deeply human, this episode is all about knowledge as empowerment. #GeneticTesting #BreastCancerAwareness #KnowledgeIsPower #CancerPrevention #brca @devin.sidell @BRCAresponder @lovedanielle.film Give us a subscribe, like and review! Find us here: Website - Perfectly Twisted Podcast • Perfectly Twisted with Nicole Eggert Mail- perfectlytwistedpod@gmail.com  Instagram - https://www.instagram.com/perfectlytwistedpodcast?igsh=YnA4NHgxMzZ4ZW56&utm_source=qr Facebook - https://www.facebook.com/profile.php?id=100090942948174&mibextid=wwXIfr Youtube - https://youtube.com/playlist?list=PLAWfs4D4mkD8mzumFj0jZrOAEHu-aOVwd&si=j8JP1R7pAQQ1xOPR Hurrdat Media - Hurrdat Entertainment | Hurrdat Media Learn more about your ad choices. Visit megaphone.fm/adchoices

Broadcast from KSQD, Santa Cruz on 3-05-2026: >ul> Dr. Dawn presents a whimsical "theme park tour" of the upper gastrointestinal tract, from saliva production triggered by sight and smell of food, through the esophageal sphincter's iris-like opening, into the stomach's pH-1 acid bath where parietal cells produce 3,000 mg of hydrochloric acid per meal. She explains protective mechanisms including the bicarbonate layer beneath stomach mucus, H. pylori's role in ulcers, and how H2 blockers and proton pump inhibitors work—cautioning about long-term PPI effects on B12 and calcium absorption. The tour continues through the pylorus into the duodenum where pancreatic enzymes and bile converge, then along the 23-foot small intestine with its tennis-court surface area of villi absorbing nutrients, iron in the duodenum, most nutrients in the jejunum, and B12 requiring intrinsic factor in the ileum. Dr. Dawn explains why pancreatic cancer—projected to become the second leading cause of cancer death by 2030—is so deadly, using a medieval castle metaphor. The tumor microenvironment acts as an impenetrable moat of desmoplastic stroma made of fibroblasts, collagen, and hyaluronic acid that blocks drugs and immune cells. Over 90% of cases have K-RAS mutations acting as growth accelerators that also thicken this protective barrier and increase CD47 "don't eat me" signals. She discusses emerging treatments including K-RAS inhibitors, PARP inhibitors for BRCA mutations, and combination immunotherapies showing 67% response rates, while noting that CAR T-cell therapy and checkpoint inhibitors alone fail because they cannot penetrate the stroma. Dr. Dawn summarizes Duke researcher Herman Ponzer's work using doubly-labeled water to measure total energy expenditure, revealing that humans burn 20-60% more calories than other great apes when adjusted for body mass. His surprising finding: Hadza hunter-gatherers walking 8-14 kilometers daily burn the same calories as sedentary Americans—the body compensates by reducing energy spent on inflammation and stress responses. This "constrained energy expenditure" model explains why exercise alone doesn't cause weight loss, though it remains crucial for preventing weight gain, reducing disease risk, and potentially tamping down harmful stress responses.

Why did Tether launch a U.S. stablecoin now? Why does Coinbase have so much influence in Congress? And what's really behind the SEC–CFTC harmonization push? Bitcoin Policy Hour breaks down the biggest regulatory stories shaping Bitcoin's future plus a deep look at the debasement trade driving gold, silver, and potentially Bitcoin higher.

A life-altering cancer diagnosis after a 30-year career in healthcare administration led Jane Rubin to find her voice—and her ancestors—through the power of historical fiction.In this episode of Real Things Living, host Brigitte Cutshall connects with two-time cancer survivor and author Jane Rubin. Jane opens up about her journey with the BRCA gene mutation, explaining how a breast cancer diagnosis actually saved her life by revealing a high genetic risk for other cancers. This health battle ignited a passion for tracing her family history, leading her to discover "Tilly Mathilda," a relative who died of a "woman's disease" in 1925 and whose name had been forgotten by time.Jane transformed these discoveries into the Gilded City trilogy, blending meticulous medical history—from the "golden window" of WWI ambulance services to the early days of reproductive rights—with the emotional resilience of the women who lived through it. Learn more about Jane Rubin and the "Gilded City Trilogy" at https://janeloberubin.comhttps://www.instagram.com/janeloebrubin/Support ovarian cancer research through the Mathilda Fund - https://www.janeloebrubin.com/mathilda-fund

In this episode of The Jordan Syatt Podcast, I speak with Elana Silber, The CEO of Sharsheret (@sharsheretofficial), a national non-profit organization that helps women and families living with breast and/or ovarian cancer.We discuss:- How Sharsheret fills the gaps in cancer support- Genetic testing and BRCA awareness- How you can get help from Sharsheret for free- How Sharsheret came to be- And more...I hope you enjoy this episode and, if you do, please leave a review on iTunes or Spotify (huge thank you to everyone who has written one so far).Finally, if you've been thinking about joining The Inner Circle but haven't yet... we have hundreds of home and bodyweight workouts for you and you can get them all here: https://www.sfinnercircle.com/