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In the fifth Season of the National Institute of Neurological Disorders and Stroke's Building Up the Nerve podcast, we help you strengthen your science communication skills with tools and advice to use throughout your career. We know that navigating your career can be daunting, but we're here to help—it's our job!In the fifth episode of the season, we talk about Securing Funding for Research focusing on choosing what funding to apply for, “pitching” your science to different funders, and writing effective grant applications.Featuring Sonya Dumanis, PhD, Executive Vice President of the Coalition for Aligning Science and Deputy Director for Aligning Science Across Parkinson's; Kat M. Steele, PhD, Associate Director of CREATE and Albert Kobayashi Professor in Mechanical Engineering at University of Washington; and Gene Yeo, PhD, MBA, Professor of Cellular and Molecular Medicine at University of California, San Diego and Chief Scientific Advisor, Sanford Laboratories for Innovative Medicine.ResourcesNIH Funding OpportunitiesSmall Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants: https://seed.nih.gov/small-business-funding/small-business-program-basics/understanding-sbir-sttr NINDS Funding Opportunities: https://www.ninds.nih.gov/funding/find-funding-opportunities NINDS Training & Career Development Opportunities: https://www.ninds.nih.gov/funding/training-career-development NIH ResourcesEarly Career Reviewer program: https://public.csr.nih.gov/ForReviewers/BecomeAReviewer/ECR NIH RePORTER: https://reporter.nih.gov/ Early Stage Investigator (ESI) Policies: https://grants.nih.gov/policy-and-compliance/policy-topics/early-stage-investigators NINDS Guidelines for incorporating rigor into grant applications: https://www.ninds.nih.gov/funding/preparing-your-application/preparing-research-plan/rigorous-study-design-and-transparent-reporting NIH Activity Codes: https://grants.nih.gov/funding/activity-codes Allen Institute's Allen Distinguished Investigators: https://alleninstitute.org/division/frontiers-group/distinguished-investigators/ Advanced Research Projects Agency for Health (ARPA-H): https://arpa-h.gov/ Aligning Science Across Parkinson's (ASAP) Disease – Collaborative Research Network (CRN): https://parkinsonsroadmap.org/research-network/# California Institute for Regenerative Medicine (CIRM) grants: https://www.cirm.ca.gov/ Transcript available at http://ninds.buzzsprout.com/.
Episode 88. Eugene Yeo is a Professor at UC San Diego and is building a scientific ecosystem in San Diego. He runs the Innovation Center at Sanford Stem Cell Institute, is Scientific Director at the Sanford Consortium, Chief Scientist at the Sanford labs for Innovative Medicines, and Director of UC San Diego's Center for RNA Technologies and Therapeutics.
Today marks the reboot of our journal club series, so you can look forward to seeing these episodes as part of our regular feed. This episode is a scientific deep dive on recent research published by Ben Cravatt, Professor in the Department of Chemistry at the Scripps Research Institute and co-founder of a diverse suite of chemoproteomic companies such as Vividion and Belharra Therapeutics, and Gene Yeo, Professor of Cellular and Molecular Medicine at the University of California, San Diego and co-founder of Locana Bio, Eclipse Bio, and Trotana Therapeutics. Ben and Gene are joined by Vineeta Agarwala, general partner at a16z Bio + Health, and bio deal team member Bryan Faust. Together, they'll discuss some unexpected mechanistic results of finding covalent binders to a class of proteins that we are just starting to understand — RNA binding proteins — and the subsequent translational implications that they described in a recent paper published by the Cravatt and Yeo labs in Nature Chemical Biology. The paper outlines a potentially new therapeutic approach that uses small molecules to fundamentally rewire transcriptional networks in cancer cells.Additional reading:Remodeling oncogenic transcriptomes by small molecules targeting NONO
University of California San Diego researcher Dr. Gene Yeo is an athlete-scientist. He has completed two Iron Man competitions, a number of half Iron Man competitions and both full and half marathons. He says: "On these long long runs and long bike rides, you know, you get the time to sort of zone out a little bit, right. And it helps you focus on, you know, answering some questions." This podcast is about his approach to his sport, how it influences his science, what his sport gives him. And it's about his science, too, which is all about RNA. (Art: J. Jackson, Music Smoothy Moody by Mac A DeMia licensed from Artlist.io)
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
There are at least 2,500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]
There are at least 2,500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]
There are at least 2,500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]
There are at least 2,500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]
There are at least 2,500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]
There are at least 2500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]
There are at least 2500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]
There are at least 2500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]
There are at least 2,500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]