Podcasts about Sequencing

In this juicy bonus Q&A episode, we tackle two big topics: what to do when a student asks you out (yep, it happens) and how to approach sequencing for an entire month without losing your mind. Along the way, our banter takes a few detours, including what it's like navigating an unequal partnership, the emotional weight of Bradshaw's first retreat after his dad's death, disassociating vs. Pratyahara, and other behind-the-scenes info. It's raw, real, and a little ridiculous, just how we like it.SEND YOUR QUESTIONS TO: CAYAYOGASCHOOL@GMAIL.COM

We're unpacking common myths around food sequencing, exercise, and nutrition for women, while addressing listener questions about dietary advice and fitness practices. You'll gain insights into the complexities of weight loss, the importance of cardiovascular exercise, and the real impact of food order on your health.

In this episode of The ICHE Podcast, we take a deep dive into the evolving role of plasma cell-free DNA (cfDNA) metagenomic next-generation sequencing (mNGS) in the diagnosis of infectious diseases. Hosted by experts from UCLA Health, this discussion breaks down what cfDNA mNGS is, how it differs from more traditional pathogen detection tools like PCR, and where it fits in the diagnostic landscape. Dr. Ishminder Kaur, Dr. Daniel Uslan, and Dr. Shangxin Yang join the episode to explore the clinical utility, benefits, and pitfalls of this rapidly emerging diagnostic modality. The group reviews several individual studies, highlighting how they approached their research questions, key findings, and the implications for patient care and antimicrobial stewardship. The conversation also addresses challenges such as interpreting complex results, cost considerations, and potential overuse. Whether you're a clinician, laboratorian, or infection preventionist, this episode provides critical insights into when and how cfDNA mNGS may enhance your diagnostic toolkit—and when it might not. Each guest closes with a practical takeaway: concrete advice for healthcare professionals who are considering incorporating cfDNA testing into their own clinical or infection control practice.

Forget 'you are what you eat.' The real game-changer? How you eat it. Science says tweaking just one thing about your meals—no willpower required—could dial up your focus, steady your mood, and keep your blood sugar in check. There is a downside though. It may make eating a little annoying. / AI pet short dramas (16:07). On the show: Steve Hatherly, Niu Honglin & Yushun

Featuring perspectives from Dr Catherine C Coombs and Dr William G Wierda, including the following topics: Introduction (0:00) Selection and Sequencing of Therapy for Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia (CLL) — Dr Wierda (19:25) First-Line Therapy for CLL — Dr Coombs (44:18) Novel Agents and Strategies for R/R CLL — Dr Wierda (57:27) CME information and select publications

In this episode, Kaila and Kyle discuss and debate the four types of jobs that they think everyone should have at least once in their career. Plus, listen ‘til the end to hear Kaila's work fail of the week.   00:00 Intro 01:06 Job #1 06:21 Pros and cons of working for a name brand  10:54 Job #2  20:04 Job #3  23:44 Job #4  29:32 Sequencing your career trajectory 32:08 Kaila's work fail of the week Want to get all of Kaila & Kyle's career resources? Subscribe to Per My Last Email: https://www.permylastemailshow.com/  Watch Per My Last Email on YouTube:   @PerMYLastEmailShow Follow Per My Last Email Instagram: @permylastemailshow TikTok: @permylastemailshow Twitter: @permylast_email Have a question for us? Send us an email or voice note to permylastemail@morningbrew.com Learn more about your ad choices. Visit megaphone.fm/adchoices Each week on Per My Last Email, Morning Brew's resident career experts Kaila and Kyle – whose careers have collectively spanned the corporate, government, nonprofit and startup sectors – debate the trickiest challenges in work life, and share tactics on how to overcome them. Share the show with a friend, and leave us a review on your favorite podcast app! Learn more about your ad choices. Visit megaphone.fm/adchoices

**Que Soul City - Sequencing Deep House - Series 1 (One)** Let us all enjoy this amazing curation of this beautiful composition by Que Soul as he rebrands from “Que Soul” to “Que Soul City”. With this mix, Is him sharing a glimpse of some of his go-to (Deep House) records. **This mix is also available in audio format on the following DSP's;** YouTube Music: https://youtu.be/DvAxLxliz9s Apple Podcasts: https://podcasts.apple.com/za/podcast/the-yanos-plenary/id1603533893?i=1000718104208 **Social Media Handles: * Instagram: https://www.instagram.com/quesoulcity?igsh=bmYydG05eHlldjNj&utm_source=qr Twitter: https://x.com/que_soul_sa?s=21 Facebook: https://www.facebook.com/share/15vrRJg8Rc/?mibextid=wwXIfr TikTok: https://www.tiktok.com/@quesoulcity?_t=ZM-8tWxiAQrxKA&_r=1 For enquiries/bookings Email: theyanosplenaryshow@gmail.com WhatsApp: 0683323651 Call: 0671496135

Stool testing technology has advanced rapidly in recent years, with newer methods like PCR and whole-genome sequencing offering faster and more precise insights into the gut microbiome. These innovations have transformed how clinicians approach gut health, allowing for more targeted interventions. However, older technologies—such as microscopy, culture, and enzyme-based assays—still play a valuable role. These methods provide functional insights that molecular tools may miss, such as direct observation of parasites or assessment of digestive markers. The most comprehensive labs recognize that no single method gives the full picture. Instead, combining the strengths of both modern and traditional techniques ensures more accurate, clinically meaningful results. In this episode, we dive into the pros and cons of different laboratory methodologies used in stool testing—from culture and microscopy to PCR and advanced sequencing. We break down how these choices impact accuracy, sensitivity, and clinical usefulness. You'll also learn why Genova Diagnostics stands out for its integrative, evidence-based approach, combining multiple testing methods to deliver the most comprehensive and clinically actionable results available. Today on The Lab Report: 4:00 Technology grows quickly, and the microbiome is complex 7:30 Microbiology culture 12:40 PCR – very precise if done correctly! 17:00 Interpreting the laundry list 20:10 Remember the microscope? 23:30 Whole-genome (shotgun) sequencing pros/cons 27:15 Genova does it all – and well Additional Resources: GI Effects Stool Profile Microbiomix Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Send us a textDo you ever find yourself happy with the lessons you are creating, only to have students forget everything a month later? Perhaps we need to slow down more? Or spiral? It's the constant question in our teacher minds: How do we help students really learn this stuff? As our guest today will argue: We Need to Be Mindful in the Way We Sequence Learning Math!Follow Dan on BlueSky: @danielk.bsky.social‬Or on Twitter: @KauDan721You can see Dan's website at: scmath.orgListened to the episode? Now, it's your turn to share! Go to our BlueSky: @DebateMath to share your thoughts. Don't forget to check out the video version of this podcast on our YouTube channel!Keep up with all the latest info by following @DebateMath or going to debatemath.com. Follow us @Rob_Baier & @cluzniak. And don't forget to rate and review us on Apple Podcasts!

Featuring perspectives from Dr Matthew D Galsky, Prof Andrea Necchi and Prof Thomas Powles, moderated by Dr Galsky, including the following topics: Introduction (0:00) Current and Future Management of Muscle-Invasive Bladder Cancer — Prof Powles (1:14) Novel Intravesical Therapies Under Evaluation for Nonmetastatic Urothelial Bladder Cancer (UBC) — Prof Necchi (24:48) Selection and Sequencing of Therapy for Metastatic UBC — Dr Galsky (44:52) CME information and select publications

Featuring perspectives from Dr Jeremy S Abramson, Dr Joshua Brody, Dr Christopher Flowers, Dr Ann LaCasce and Dr Tycel Phillips, moderated by Dr Abramson, including the following topics: Introduction (0:00) Selection and Sequencing of Available Therapies for Diffuse Large B-Cell Lymphoma — Dr Flowers (2:24) Evolving Management Paradigm for Mantle Cell Lymphoma — Dr Phillips (31:53) Integration of Novel Therapies into the Management of Follicular Lymphoma — Dr LaCasce (54:51) Integrating Bispecific Antibodies into the Management of Non-Hodgkin Lymphoma (NHL) — Dr Brody (1:11:22) Current Role of CAR T-Cell Therapy in Various NHL Subtypes — Dr Abramson (1:37:55) CME information and select publications

Featuring perspectives from Dr Harold J Burstein, Dr Javier Cortés, Prof Rebecca A Dent, Dr Kevin Kalinsky, Dr Hope S Rugo and Dr Joyce O'Shaughnessy, moderated by Dr Rugo, including the following topics: Introduction (0:00) Optimizing the Management of HER2-Positive Metastatic Breast Cancer (mBC) — Dr Cortés (3:52) Individualized Selection of Up-Front Therapy for Patients with HR-Positive, HER2-Negative mBC — Dr Kalinsky (23:10) Available Therapies for Patients with HR-Positive, HER2-Negative Disease Progressing on CDK4/6 Inhibition — Dr Burstein (48:09) Current and Potential Future Role of HER2-Targeted Therapy for HER2-Low and HER2-Ultralow Disease — Dr O'Shaughnessy (1:04:00) Current and Future Strategies for Patients with Endocrine-Refractory HR-Positive mBC — Dr Rugo (1:22:28) Selection and Sequencing of Therapy for Patients with Metastatic Triple-Negative Breast Cancer — Prof Dent (1:42:51) CME information and select publications

Send us a textThe conventional approach to withdrawing retirement funds generally involves withdrawing from taxable accounts first, followed by tax-deferred accounts, and finally tax-free accounts. This strategy can minimize taxes and maximize the growth of tax-advantaged investments. Does that mean that this is the best approach for everyone? Like most retirement-related topics, the answer is not a simple yes or no. If you'd like to be a part of a free online retirement community, join us on Facebook: https://www.facebook.com/groups/399117455706255/?ref=share

Avelumab first-line maintenance is an approved treatment for cisplatin-eligible or -ineligible patients with advanced urothelial carcinoma (UC) who are progression free following first-line platinum-based chemotherapy, based on the results of the JAVELIN Bladder 100 phase 3 trial. In recent years, an increasing number of real-world studies have examined the effectiveness and safety of avelumab first-line maintenance in heterogeneous populations from different countries, expanding the clinical evidence base. In this podcast, Dr. Petros Grivas from the University of Washington, Fred Hutch Cancer Center, Seattle, WA, USA, and Dr. Helen H. Moon from Kaiser Permanente, Riverside, CA, USA, discuss findings from these real-world studies, which have complemented clinical trials and provided additional insights about overall effectiveness, treatment sequencing involving second-line enfortumab vedotin monotherapy or other options, and healthcare resource utilization. They also briefly discuss the evolving treatment landscape in advanced UC in addition to benefits and limitations of real-world studies in general. This podcast is published open access in Targeted Oncology and is fully citeable. You can access the original published podcast article through the Targeted Oncology website and by using this link: https://link.springer.com/article/10.1007/s11523-025-01162-4. All conflicts of interest can be found online. Open Access This podcast is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The material in this podcast is included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

Modern day students have a great debt of gratitude to the Vedic masters who have captured and preserved Vedic wisdom for millennia, making it available for us to apply to our lives today.One of the most prolific of these masters is Veda Vyasa, who is recognized as being responsible for documenting as much as three quarters of the Vedic literature, and organizing, or “sequencing” it, in such as way that we are still able to access and apply the wisdom even today.In this episode, which includes questions from audience members, Thom gives as a brief insight into the life and work of Veda Vyasa, the Cosmic storyteller.It's a fitting prelude to Thom's upcoming residential course, Vedanta Vyasa, to be held in Sedona this coming July. If this episode whets your appetite for more, and if you have passed the prerequisites for attending, we invite you to visit the website to find out more. Episode Highlights:[00:45] Vyasa - A Teller of Sequence[03:59] The Many Names of Vyasa[09:59] Sanskrit - Correlating Name and Form[14:25] Recognizing Patterns in the Veda[19:20] The Upavedas[23:27] Mahabharata - The Epic of Great India[25:54] The Play and Display of Elevational Theater[29:08] Breaking the Fourth Wall[32:00] Fabulous Stories Delivering Lessons to Live By[35:25] A Comprehensive Body of Work[39:43] Vedanta - The Final Conclusion[43:10] An Invitation to Explore Vyasa's Story with Thom[45:49] The Connotative - The Proper View of Ancient Texts[50:35] Q - Does Vyasa's Breaking of the Fourth Wall Have Any Implications for Free Will?[51:00] The Free Will to Determine Everything[54:46] Changing the Storyline[57:36] Q - Was Maharishi Mahesh Yogi the Vyasa of this Age?[58:04] Demonstrating Vyasa-like Sequencing of Knowledge[01:00:34] Reality is Different in Different States of Consciousness[01:04:30] Sensory Perception Brings OnenessUseful Linksinfo@thomknoles.com https://thomknoles.com/https://www.instagram.com/thethomknoleshttps://www.facebook.com/thethomknoleshttps://www.youtube.com/c/thomknoleshttps://thomknoles.com/ask-thom-anything/

(00:01) Powerful Golf Swing Techniques for Distance This chapter explores the importance of power in golf, emphasizing how crucial it is to utilize the ground effectively for better performance. Broadcasting from Talking Rock Ranch in Prescott, Arizona, we discuss the mechanics of power in the golf swing, explaining that it all starts from the ground up. By pushing against an immovable object like the ground, energy is generated and transferred through the body to the arms, enhancing the swing's speed and effectiveness. We highlight the common misconception that power is solely about body rotation, when in reality, timing the push against the ground is key. Through power schools and practical demonstrations, we explain how to harness this energy properly, ensuring that it is released at the right moment in the swing for maximum impact. (12:25) Swing Sequencing Tools for Golf This chapter focuses on the importance of proper sequencing in a golf swing and how it impacts energy transfer from the lower body through to the club. We explore the common issue of being out of sequence, where the arms move ahead of the torso, leading to inefficient swings. A simple solution proposed is using a rope to practice, as it naturally enforces correct sequencing since you cannot push on it. This technique helps maintain the correct order of movement: lower body, torso, arms, and then the club. Additionally, I introduce a homemade training aid using a PVC pipe inside a swim noodle to provide comfort while practicing chest rotations. This tool helps protect the arms and chest, ensuring a comfortable and effective practice session. (23:51) Improving Golf Ball Striking Technique This chapter explores the relationship between club head speed and effective ball striking in golf. While increasing club head speed is often emphasized for achieving greater distance, it is crucial to maintain contact with the center of the club face to optimize ball speed and overall performance. The importance of ball speed, spin, and launch angle in achieving longer shots is highlighted, and the potential pitfalls of focusing solely on club head speed are discussed. Additionally, the benefits of practicing with specialized equipment, such as the Tour Striker club, are examined. This unique club design encourages proper striking technique by requiring the golfer to drive the club downward and forward, thereby enhancing ball striking ability and maximizing smash factor. (27:04) Improving Distance With Proper Swing Integration This chapter explores the nuances of improving your golf game with specialized equipment and techniques. I discuss the benefits of using the Tour Striker club, which requires precise ball striking due to its design that forces players to de-loft the club for optimal launch angles and distance. Additionally, I emphasize the importance of hitting the center of the clubface to enhance distance and control, regardless of whether you're using the latest technology or a five-year-old driver. We also talk about using training aids with smaller club heads to improve accuracy and consistency. Furthermore, we cover tips on proper tee height and swing mechanics to achieve the desired launch angle and reduce spin. Finally, there's a humorous look at the use of martini tees and the common mistake of setting them too low, which can impact performance. (42:29) Putting Technique Improvement Through Visualization This chapter explores the importance of clarity and specificity in putting techniques, emphasizing the use of training tools like a putting rail to ensure the shaft and head of the putter move straight back and through. We discuss how the putter head will naturally arc, and it's crucial to focus on the straight movement of the hands and arms. I also share a personal anecdote about improving my pitching skills with Jeff's guidance, which has positively impacted my overall game. Notably, I overcame challenges with my five iron, successfully executing a beautiful 168-yard shot onto the green, highlighting the interconnectedness of honing different golf skills.

 In 2020, A. Wes Mitchell wrote a document to be considered by the Office of Net Assessment of the Department of Defense entitled “Strategic Sequencing: How Great Powers Avoid Multi-Front Wars”.  We discuss this document and consider the question does this article provide a possible framework for the US Ruling class maintaining empire or THE framework for how it has approached this question? Check us out!https://youtu.be/nItmqkrpWHU To see all our episodes go to:What's Left? Website: https://whatsleftpodcast.com/iTunes: Spotify: Bitchute: YouTube:  LBRY: Telegram :Odysee:  Googleplaymusic: Rumble 

Sequencing with purpose transforms the yoga practice and our teaching. Today we're going deep on gait, a pillar of my Flow School method, and its application in creating more intuitive, sustainable sequences.Learn more about Flow School hereWeekly stories by email from Bonnie's HERE Connect with Bonnie: Instagram, Email (hello@bonnieweeks.com), WebsiteListen to Bonnie's other podcast Sexy Sunday HERE The music for this episode is Threads by The Light Meeting. Produced by: Grey Tanner

In this episode of On AIRR, Dr. Paul Thomas, reviews advances in the field of TCR sequencing. Dr. Thomas is a faculty member in the Department of Immunology of St. Jude Children's Research Hospital. His work has advanced our understanding of innate and adaptive immune responses and TCR specificity with a focus on responses to viral infections. In Episode 18 of On AIRR, Dr. Thomas shares his journey from immunoparasitology to pioneering TCR repertoire sequencing. He began his scientific career studying innate immune responses to parasites during his graduate work in immunoparasitology. Motivated by a desire to use advanced molecular techniques, he moved to St. Jude for his postdoctoral research, where he contributed to the development of TCR repertoire sequencing methods. The discussion covers the evolution from single-chain TCR sequencing to the development of high-throughput paired sequencing methods, culminating in the TIRTL-seq approach. Dr. Thomas explains the technical and computational challenges in TCR pairing, the innovations that made large-scale studies possible, and the importance of data quality and curation in the field. The episode highlights the impact of these advances on understanding immune responses and the future of AIRR-based diagnostics. Comments are welcome to the inbox of onairr@airr-community.org or on social media under the tag #onAIRR. Further information can be found here: https://www.antibodysociety.org/the-airr-community/airr-c-podcast. The episode is hosted by Dr. Ulrik Stervbo and Dr. Zhaoqing Ding.  Announcements and links Paul Thomas Lab https://www.stjude.org/research/labs/thomas-lab.html  Other: TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing https://doi.org/10.1101/2024.09.16.613345   TIRTL-seq repository: https://github.com/pogorely/TIRTL Adaptive Immune Receptor Repertoire Community (AIRR-C) https://www.airr-community.org The Antibody Society (TAbS) https://www.antibodysociety.org AIRR-C Seminar Series s https://www.antibodysociety.org/the-airr-community/airr-community-seminar-series/

What if chasing wealth was actually costing you your health—and slowing your business growth? In today's episode of The Mind of George Show, George reconnects with Mauro Stara, CEO of Six Pack CEO, to reveal the critical connection between peak performance, biological health, and entrepreneurial success. Mauro shares why entrepreneurs can't afford to delay their health journey, how to optimize core pillars like sleep and recovery, and why mastering your biology is your ultimate business advantage. If you're ready to stop grinding and start thriving, this episode is your blueprint.What You'll Learn in This EpisodeHow delaying your health journey is costing you business growthThe four foundational pillars for achieving peak performanceWhy mastering your recovery is more powerful than working harderHow your biology is either your biggest asset—or your biggest liabilitySimple, actionable shifts to optimize your energy, focus, and health starting todayKey Takeaways✔️Prioritize Health Early: Waiting for financial success before focusing on health actually slow down business success.✔️The Four Pillars: Recovery (sleep and stress management), nutrition, resistance training, and daily activity are the foundation of sustainable high performance.✔️Optimize Recovery, Not Just Effort: You don't need to work less—you need to recover better.✔️Focus on Simplicity, Not Biohacks: Master the basics like consistent sleep, sunlight exposure, movement, and nutrition before diving into complex optimization tools.✔️Track with Data: Blood work is critical to tailoring your optimization journey—don't just copy influencers or random online advice. Timestamps[00:00] The trap of “I'll prioritize my health when I hit my goals”[02:00] Why biology dictates business success[04:00] Meet Mauro Stara and the Six Pack CEO philosophy[06:00] Sequencing priorities: how health impacts wealth[10:00] Investing in your biology for accelerated growth[18:00] The Four Pillars of Peak Performance[22:00] Burnout: under-recovery vs. overwork[28:00] How deep sleep and REM impact your hormones and recovery[33:00] How eating timing affects blood sugar and sleep quality[38:00] Why simple habits beat fancy biohacks every time[45:00] Common mistakes in chasing peak performance[52:00] How to use blood work to guide your optimization[57:00] The mindset shift: there is no “finish line” for your health Choose Your Next Steps:Audit your core pillars: sleep, nutrition, training, and activity. Pick ONE area where you can make a simple improvement this week—and commit to it for the next 7 days.Bonus: DM George or Mauro and share what pillar you're committing to upgrade!Connect with Mauro Stara:Instagram: @maurostaraofficialWebsite: sixpackceo.comJoin The Alliance – The Relationship Beats Algorithms™ community for entrepreneurs who scale with trust and connectionApply for 1:1 Coaching – Ready to build your business with sustainability, impact, and ease? Apply hereLive Events – Get in the room where long-term success is built: mindofgeorge.com/event

Featuring perspectives from Dr Farshid Dayyani, Ms Caroline Kuhlman, Dr Philip A Philip and Ms Amanda K Wagner, including the following topics: Introduction: Initial Management of Pancreatic Adenocarcinoma (PAD) (0:00) Clinical Presentation and Prognosis of PAD; Recent Advances in Up-Front Treatment for Metastatic PAD (19:01) Selection and Sequencing of Therapy for Relapsed/Refractory Metastatic PAD (54:38) Importance of Palliative Care for Advanced PAD (1:06:09) Role of PARP Inhibitor Maintenance Therapy for Newly Diagnosed Metastatic PAD (1:14:59) Promising Investigational Strategies for PAD (1:26:56) NCPD information and select publications

Featuring an interview with Dr Rafael Fonseca, including the following topics: Safe management of bispecific antibodies and chimeric antigen receptor (CAR) T-cell therapy for patients with multiple myeloma (MM) (0:00) Sequencing bispecific antibodies and CAR T-cell therapy (10:40) Available data with and potential future clinical integration of belantamab mafodotin in the management of MM (16:03) Optimizing maintenance therapy for patients with MM (31:11) Novel management strategies for smoldering myeloma (36:29) Role of anti-CD38 antibodies in the up-front management of MM (41:41) Available data with cereblon E3 ligase modulatory drugs for MM (47:45) CME information and select publications

In this podcast episode, host Ruchika Talwar, MD, is joined by Amin Mazloom, PhD, Senior Vice President of Bioinformatics, Biostatistics & Data Innovation, and Janine LoBello, DO, Senior Clinical Laboratory Medical Director at Exact Sciences to discuss patient-matched tumor-normal (PMTN) sequencing and why it matters for oncologists. Drs. Mazloom and LoBello discuss PMTN sequencing as a gold standard method for calculating tumor mutational burden and personalized therapy selection and share their thoughts on the future of cancer testing.

In this podcast episode, host Ruchika Talwar, MD, is joined by Amin Mazloom, PhD, Senior Vice President of Bioinformatics, Biostatistics & Data Innovation, and Janine LoBello, DO, Senior Clinical Laboratory Medical Director at Exact Sciences to discuss patient-matched tumor-normal (PMTN) sequencing and why it matters for oncologists. Drs. Mazloom and LoBello discuss PMTN sequencing as a gold standard method for calculating tumor mutational burden and personalized therapy selection and share their thoughts on the future of cancer testing.

Episode 386 Show Notes Topic of the show: VFR Vectors to Final. Sponsored by SGAC Patron SA On this week's show, RH and AG discuss sequencing VFR's to a Charlie airport and the etiquette involved on both sides of the mic.  We also discuss a real life center controller sighting, confusing late night flying mistakes, and more of your awesome aviation feedback.  Links: https://youtu.be/Dml3O6Irmt0 Timely Feedback: 1. Army IP DS answers the radar altimeter question from last week, thanks! 2. Patron SRD answers the radar altimeter question also, thank you! 3. Patron BDM asks about controllers after an incident 4. Patron JAC sends a story about his first solo cross country Feedback 1. Patron TS discusses shift work as a submariner 2. Harrier the Bean sends several interactions with ATC 3. Patron SG sends audio about audio 4. Patron DDC talks night flying for IFR training 5. Patron DB talks about a recent Center tour Have a great week and thanks for listening!  Visit our website at OpposingBases.com You can support our show using Patreon or visiting our support page on the website.  Keep the feedback coming, it drives the show! Don't be shy, use the “Send Audio to AG and RH” button on the website and record an audio message. Or you can send us comments or questions to feedback@opposingbases.com.  Music bumpers by audionautix.com.  Third party audio provided by liveatc.net.  Legal Notice The views and opinions expressed on Opposing Bases Air Traffic Talk are for entertainment purposes only and do not represent the views, opinions, or official positions of the FAA, Penguin Airlines, or the United States Army.  Episodes shall not be recorded or transcribed without express written consent. For official guidance on laws, rules, and regulations, consult an aviation attorney or certified flight instructor.

In this episode of The Perceptive Photographer, I dive into the relationship between form and content in photography, especially when editing and sequencing a body of work. While a photo might carry personal meaning for me, I know it doesn't inherently hold that story for the viewer—it's their interpretation that brings it to life. That's why I encourage photographers to critically assess what's included and excluded in the frame to better communicate their intent.

Featuring an interview with Dr Lindsey Roeker, including the following topics: Clinical development of novel Bruton tyrosine kinase (BTK) degraders in therapy for chronic lymphocytic leukemia (CLL) (0:00) Safety of BTK inhibitors in older and frail patients with CLL (3:41) Utility of minimal residual disease-guided treatment with venetoclax/obinutuzumab (9:20) Impact of the AMPLIFY study of acalabrutinib with venetoclax with or without obinutuzumab in CLL (16:32) Utility of acalabrutinib, venetoclax and obinutuzumab for high-risk CLL (23:31) Emerging data with sonrotoclax and zanubrutinib in treatment-naïve CLL (25:16) Sequencing, tolerability and future development involving pirtobrutinib (25:57) Emerging data with the addition of a BTK inhibitor to chimeric antigen receptor T-cell therapy (32:28) Clinical considerations in the management of Richter's transformation (38:14) Survival outcomes and quality of life for patients with CLL (41:02) Ongoing and future efforts to improve CLL treatment outcomes (45:01) CME information and select publications  

Featuring a slide presentation from Dr Matthew Matasar and related discussion from Dr Carla Casulo, Dr Matasar and Dr Laurie H Sehn, including the following topics: EZH2 Inhibitors for Follicular Lymphoma (FL) (0:00) Bruton Tyrosine Kinase Inhibitors for FL (5:43) Anti-CD19 Antibodies for FL (9:40) Other Novel Agents Under Clinical Development for FL (18:50) Case: A woman in her early 80s with multiple comorbidities and relapsed FL (23:06) Case: A man in his early 40s with high-risk progressive FL that did not achieve deep remission with prior therapy (27:07) Case: A woman in her early 70s with rheumatoid arthritis and relapsed FL (33:46) CME information and select publications

Dr Carla Casulo from Wilmot Cancer Institute in Rochester, New York, Dr Matthew Matasar from Rutgers Cancer Institute of New Jersey in New Brunswick and Dr Laurie H Sehn from BC Cancer Centre for Lymphoid Cancer in Vancouver discuss recent updates on available and novel treatment strategies for relapsed/refractory follicular lymphoma. CME information and select publications here.

Featuring perspectives from Dr Paul E Oberstein and Dr Philip A Philip, including the following topics: Selection and Sequencing of Therapy for Patients with Metastatic Pancreatic Adenocarcinoma (PAD) — Dr Oberstein (0:00) Biomarker-Based Strategies for Metastatic PAD; Novel Investigational Approaches — Dr Philip(30:57) CME information and select publications

Featuring a slide presentation from Dr Matthew Matasar and related discussion from Dr Carla Casulo, Dr Matasar and Dr Laurie H Sehn, including the following topics: Overview of Chimeric Antigen Receptor (CAR) T-Cell Therapies for Relapsed/Refractory Follicular Lymphoma (FL) (0:00) Case: A man in his late 60s with relapsed FL who received axicabtagene ciloleucel (axi-cel) but experienced cytokine release syndrome, immune effector cell-associated neurotoxicity syndrome and chronic cytopenia (3:50) Published Clinical Data Involving Axi-cel (10:24) Case: A man in his mid 60s with multiple comorbidities and progressive FL who received tisagenlecleucel (tis-cel) (15:34) Published Clinical Data Involving Tis-cel (19:47) Case: A woman in her late 40s with multiple comorbidities and refractory FL who received lisocabtagene maraleucel (liso-cel) after prior mosunetuzumab (22:43) Published Clinical Data Involving Liso-cel (26:05) Incidence and Management of Toxicities Associated with CAR T-Cell Therapy (27:48) Sequencing Considerations and Ongoing Trials Involving CAR T-Cell Therapy (30:35) Practical Considerations and Referrals for CAR T-Cell Therapy Administration (31:59) CME information and select publications

Dr Carla Casulo from Wilmot Cancer Institute in Rochester, New York, Dr Matthew Matasar from Rutgers Cancer Institute of New Jersey in New Brunswick and Dr Laurie H Sehn from BC Cancer Centre for Lymphoid Cancer in Vancouver discuss recent updates on available and novel treatment strategies for relapsed/refractory follicular lymphoma. CME information and select publications here.

This episode teaches that innovation is born at the intersection of curiosity and persistence. Dr. Gudrun Stengel, co-founder and CEO of Alida Biosciences, reveals how her startup is transforming the landscape of RNA research through a novel technology called proximity barcoding. Dr. Stengel's story exemplifies the power of entrepreneurial spirit in driving scientific discovery, offering a glimpse into how one idea can reshape an entire field.At Alida Biosciences, Dr. Stengel and her team are pioneering new tools for detecting RNA modifications, a largely unexplored realm of epigenetics. Using their proximity barcoding platform, researchers can read multiple RNA modifications simultaneously, uncovering potential biomarkers and therapeutic targets for diseases like cancer, Alzheimer's, and diabetes. This technology bridges a critical gap in multiomics, allowing scientists to dive deeper into how epigenetic changes influence gene expression and cellular behavior.Beyond the lab, Dr. Stengel shares her experience as a first-time founder, balancing scientific rigor with startup life. From managing a team to fundraising, her journey underscores the importance of resilience, optimism, and maintaining a long-term vision. She also offers valuable advice for budding scientists, encouraging them to embrace challenges and remain persistent in the face of setbacks. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

In this thrilling installment of Impact Theory, Tom Bilyeu sits down with Ben Lamm, visionary founder and CEO of Colossal Biosciences, a company on a mission to reverse extinction and rewrite the future of conservation and synthetic biology. Ben and Tom dive deep into the mind-bending world of de-extinction, synthetic gene editing, and how the CRISPR revolution is not only unlocking the secrets of life—but also actively engineering it. In Part 1, get ready for a rollercoaster of concepts as Ben explains the technical magic behind gene editing, DNA synthesis, and multiplex genome editing. From the birth of the woolly mouse to the debated revival of dire wolves, Ben reveals the breakthroughs, challenges, and wild stories behind reviving extinct species. You'll learn how Colossal is using advanced computational biology, AI, and hands-on bioengineering to not only bring animals back but also reshape the future of healthcare, genetics, and ethical decision-making. This is part sci-fi, part practical science, and 100% mind-blowing. SHOWNOTES 00:00 – Kicking Off: The Mysteries of Editing Life 00:14 – Emergence of the CRISPR Revolution 01:31 – What Is DNA Synthesis and Multiplex Editing? 03:47 – The Woolly Mouse: Engineering Traits Across Species 07:54 – Breaking Down the Process: IVF, Screening, and Sequencing 09:24 – Mapping Genotype to Phenotype and Its Challenges 12:10 – Targeting Gene Edits: From Theory to Application in Health and Conservation 17:09 – From Hair Organoids to Building Mammoth Traits in Mice 24:41 – The Quest for a Universal Egg and Overcoming Cellular Barriers 26:17 – Artificial Wombs: The Next Frontier in Conservation and Science 31:12 – Scaling Conservation and Bridging to Human Healthcare FOLLOW BEN LAMM Twitter/X: @federallamm LinkedIn: Ben Lamm CHECK OUT OUR SPONSORS ButcherBox: Ready to level up your meals? Go to ⁠https://ButcherBox.com/impact⁠ to get $20 off your first box and FREE bacon for life with the Bilyeu Box! Vital Proteins: Get 20% off by going to ⁠https://www.vitalproteins.com⁠ and entering promo code IMPACT at check out Shopify: Sign up for your one-dollar-per-month trial period at ⁠https://shopify.com/impact⁠ Netsuite: Download the CFO's Guide to AI and Machine Learning at ⁠https://NetSuite.com/THEORY⁠ iTrust Capital: Use code IMPACTGO when you sign up and fund your account to get a $100 bonus at ⁠https://www.itrustcapital.com/tombilyeu⁠  Mint Mobile: If you like your money, Mint Mobile is for you. Shop plans at ⁠https://mintmobile.com/impact.⁠  DISCLAIMER: Upfront payment of $45 for 3-month 5 gigabyte plan required (equivalent to $15/mo.). New customer offer for first 3 months only, then full-price plan options available. Taxes & fees extra. See MINT MOBILE for details. What's up, everybody? It's Tom Bilyeu here: If you want my help... STARTING a business: join me here at ZERO TO FOUNDER SCALING a business: see if you qualify here. Get my battle-tested strategies and insights delivered weekly to your inbox: sign up here. ********************************************************************** If you're serious about leveling up your life, I urge you to check out my new podcast, Tom Bilyeu's Mindset Playbook —a goldmine of my most impactful episodes on mindset, business, and health. Trust me, your future self will thank you. ********************************************************************** LISTEN TO IMPACT THEORY AD FREE + BONUS EPISODES on APPLE PODCASTS: apple.co/impacttheory ********************************************************************** FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu Learn more about your ad choices. Visit megaphone.fm/adchoices

Cancer is among the most common and feared diseases in the modern world. Dr. Selwyn Vickers—president and CEO of Memorial Sloan Kettering Cancer Center—joins host Mark Labberton to discuss how precision oncology, data, and faith are transforming cancer treatment. A distinguished cancer surgeon and pancreatic cancer researcher, Vickers explains how groundbreaking advances in genomics, immunotherapy, and AI are transforming once-lethal diagnoses into survivable and even chronic conditions. Together, they explore not only the cutting-edge science of cancer care but also the spiritual, emotional, and social dimensions that affect every patient and caregiver. Resonating with themes of suffering, hope, and resurrection, this conversation offers clarity, compassion, and courage for all who are affected by cancer—from those newly diagnosed, to medical professionals, to grieving families and curious listeners. Episode Highlights “We're getting to a point where we will, in the next five to seven years, have a much better chance to cure people—and to make pancreatic cancer a chronic illness.” “We are in what's somewhat coined the golden age of cancer research.” “Cancer is a disease that creates an existential threat in ways no other illness does.” “If a tumour forms, it means your body's immune system has made a social contract with the cancer.” “We changed the diagnosis in 10–12 percent of the patients who come to us—sometimes from cancer to no cancer.” “Cancer care is a team sport. And our patients often inspire us more than we help them.” Helpful Links & Resources Memorial Sloan Kettering Cancer Center BioNTech – creators of mRNA vaccines for COVID and cancer CAR T-Cell Therapy Overview (Cancer.gov) Tim Keller on cancer and hope Emma Thompson's Wit (HBO) BRCA1 and BRCA2 Genes and Cancer Risk MSK-IMPACT: Next-Gen Tumor Profiling About Selwyn Vickers Selwyn M. Vickers, MD, FACS, is the president and CEO of Memorial Sloan Kettering Cancer Center (MSK) and the incumbent of the Douglas A. Warner III Chair. He assumed the role on September 19, 2022. Vickers is an internationally recognized pancreatic cancer surgeon, pancreatic cancer researcher, and pioneer in health disparities research. He is a member of the National Academy of Medicine and the Johns Hopkins Society of Scholars. He has served on the Johns Hopkins School of Medicine Board of Trustees and the Johns Hopkins University Board of Trustees. Additionally, he has served as president of the Society for Surgery of the Alimentary Tract and the Southern Surgical Association. Vickers is the immediate past president of the American Surgical Association. He also continues to see patients. In 1994, he joined the faculty of the University of Alabama at Birmingham (UAB) as an assistant professor in the Department of Surgery, where he was later appointed to professor and the John H. Blue Chair of General Surgery. In 2006, Vickers left UAB to become the Jay Phillips Professor and Chair of the Department of Surgery at the University of Minnesota Medical School. Born in Demopolis, Alabama, Vickers grew up in Tuscaloosa and Huntsville. He earned baccalaureate and medical degrees and completed his surgical training (including a chief residency and surgical oncology fellowship) at the Johns Hopkins University. Vickers completed two postgraduate research fellowships with the National Institutes of Health and international surgical training at John Radcliffe Hospital of Oxford University, England. Vickers and his wife, Janice, who is also from Alabama, have been married since 1988. They have four children. Show Notes The ongoing threat and fear of cancer How Selwyn Vickers got into medicine Pancreatic cancer: Vickers's expertise “We are in what's somewhat coined the golden age of cancer research.” Sequencing the human genome “Is there a drug that might target the mutation that ended up creating your cancer?” Cancer as both a medical and existential diagnosis The revolution of precision oncology through human genome sequencing ”It takes a billion cells to have a one centimetre tumor.” Immunotherapy: checkpoint inhibition, CAR T-cell therapy, and vaccines Cellular therapy:   ”Taking a set of their normal cells and re-engineering them to actually go back and target and attack their tumors. … We've seen patients who had initially a 30 percent chance of survival converted to an 80 percent chance of survival.” “We know in many tumours there's something called minimal residual disease.” “Immunizing yourself against cancer is a significant future opportunity.” Managing the power of data with AI and computational oncology Cancer-care data explosion: the role of computational oncologists Cancer vaccines: breakthrough mRNA treatment for pancreatic cancer ”Didn't ultimately win. We had to suffer through her losing her life, but was so appreciative that she got much more than the six months she was promised.” Tumour misdiagnoses and the importance of specialized expertise Pancreatic cancer challenges: immune cloaking and late-stage detection In the past, one in four would die from the operation for removing pancreatic cancer Long-term survival Future of cancer detection: AI-based medical record analysis and blood biopsies More accurate blood tests to confirm conditions Using AI to select those who are high-risk for cancer Pastor Tim Keller died of pancreatic cancer. In the past, “your doctor … helped you learn how to die.” ”[God's] given man the privilege to discover those things that have been hidden. And over time we've gradually uncovered huge opportunities to impact people's lives.” The state of breast cancer research and treatment “If you get the diagnosis of breast cancer, you have a 90 percent chance to survive and beat it over a five-year period of time.” ”In general, we're in a great state of understanding how to treat breast cancer, how to detect it early, and then have selective and targeted mechanisms to prevent it from coming back.” Prostate cancer research and treatment Theranostics: using a specific antibody to target cancer cells specifically Pediatric cancer:  ”We actually treat more children for cancer than any hospital in America now, but in general, the survival for pediatric cancers is greater than 80 percent.” Emotional, psychological, and spiritual toll of cancer: importance of psycho-oncology How Sloan Kettering developed psycho-oncology to help cancer patients with mental and spiritual health Personal story: how a cafeteria worker empowers patients through food choices “We give back to them the right to choose what they get to have on their tray.” Cancer treatment is a team sport. Wit (film, Broadway play)—actress Emma Thompson plays a cancer patient studying the work of John Donne on death Socioeconomic and racial disparities in cancer care outcomes The healing role of community, support teams, and compassionate listening The importance of listening to cancer patients who are preparing to die The spiritual courage of patients and the transformative power of faith “Our patients often help us. We see the grace with which they often handle that journey.” The inspiration behind becoming a doctor: family legacy and human impact Terminal care: the sacred responsibility of walking with patients to the end Cancer research and treatment as a Christian vocation and expression of humanity Production Credits

Featuring an interview with Dr John P Leonard, including the following topics: First-line therapy for diffuse large B-cell lymphoma (DLBCL) with polatuzumab vedotin and R-CHP; impact of DLBCL cell of origin (0:00) Epcoritamab, glofitamab and other bispecific antibodies as initial therapy for large B-cell lymphoma (9:27) Sequencing chimeric antigen receptor T-cell therapy and bispecific antibodies for patients with relapsed/refractory (R/R) DLBCL (12:30) Approved and investigational bispecific antibodies for the treatment of DLBCL (15:24) Practical considerations for the administration of mosunetuzumab (22:03) Tafasitamab combined with lenalidomide/rituximab as second-line treatment for follicular lymphoma (FL); third- and later-line therapy options (24:33) Activity of Bruton tyrosine kinase inhibitors in FL and other non-Hodgkin lymphomas (31:27) Risk of infection for patients receiving bispecific antibodies (33:23) Chemotherapy-free regimens for the treatment of mantle cell lymphoma (MCL) (36:21) Current role of transplant in the treatment algorithm for MCL; potential integration of bispecific antibodies into therapy for R/R disease (41:23) Myths and misperceptions about the management of DLBCL, FL and MCL (47:29) CME information and select publications

Feeling overwhelmed by a never-ending task list? The most successful people don't do everything, they do the right things in the right order. This clip breaks down why mastering sequencing is the secret to growing in life and business without burning out. Learn to prioritize what truly matters, and build a schedule that honors both your hustle and your health. Longevity wins.Get access to our real estate community, coaching, courses, and events at Wealthy University https://www.wealthyuniversity.com/Join our FREE community, weekly calls, and bible studies for Christian entrepreneurs and business people. https://www.wealthykingdom.com/ If you want to level up, text me at 725-527-7783!--- About Ryan Pineda: Ryan Pineda has been in the real estate industry since 2010 and has invested in over $100,000,000 of real estate. He has completed over 700 flips and wholesales, and he owns over 650 rental units. As an entrepreneur, he has founded seven different businesses that have generated 7-8 figures of revenue. Ryan has amassed over 2 million followers on social media and has generat...

Movement in the music room doesn't have to be chaotic, and it definitely shouldn't start with a complex folk dance if your students have never done movement before! In this episode of That Music Podcast, Bryson breaks down a more intentional and developmentally appropriate approach to introducing movement in your classroom. You'll learn how to scaffold movement experiences so that your students can grow in confidence and coordination over time. From unstructured exploration to guided movement and finally structured activities, Bryson shares practical strategies to help students feel successful every step of the way. Whether you're new to using movement or just looking for a smoother process, this episode will help you set your students up for success, without the chaos. Episode Chapters: 0:00 Introduction 2:04 The 3 Steps Toward Structure 8:23 Takeaways Links and Resources: Elementary Newbie Guide Disabilities Guide Steady Beat Survival Guide Join That Music Teacher Community Have questions or want to share feedback? Reach out to us at hello@thatmusicteacher.com - we'd love to hear from you!

This one starts off strong — Bradshaw and Giana chat about house elves, some important announcements, and a very crucial update about Bradshaw's date with his dream guy (trust us, it's a story worth sticking around for).After the laughs, they dive into the real topic: Why Creative Sequencing Isn't Everything.They break down what creative sequencing actually is, why some teachers may lean heavily into it, and why it can sometimes be counterproductive. Giana and Bradshaw explore how sequencing shapes the overall experience of yoga — and how overly complex or random flows can sometimes feel chaotic, create confusion, and pull students away from the heart of the practice.They advocate for meeting students where they are, building them up thoughtfully, and recognizing that being in an overly anticipatory state (always wondering "what's next") can actually detract from the yoga itself. Instead of simply leaving students feeling good in the moment, they believe great sequencing should help students both feel and learn — ideally, it should do both.They also touch on essential topics like safety, accessibility, and the big question: Who is the creative sequencing really for — the student or the teacher?Expect real talk, real laughs, and a real reminder of what yoga is truly about.UPCOMING RETREAT:Starved Rock Yoga Retreat (JULY): https://www.cayayogaschool.com/starvedrockYoga Teachers Retreat: Costa Dulce, Nicaragua (MARCH 2026): https://cayayogaschool.com/pages/teachers-retreatBE PART OF OUR FUNNY FAM: https://www.cayayogaschool.com/communityPODCAST SUBSTACK: https://thefunnythingaboutyoga.substack.com/FOLLOW US:@thefunnythingaboutyoga @cayayogaschool @gianagambino @bradshawwishLINKS:https://www.cayayogaschool.com/https://www.gianayoga.com/ Hosted on Acast. See acast.com/privacy for more information.

This week I'm joined by Taylor Lorenz oftaylorstracks.com and @taylorstracks. Taylor is the creator of the yoga & travel site, Taylor's Tracks, a former full-time travel writer turned yoga teacher, mentor & trainer after taking her first YTT that sparked her self acceptance journey. We talk about ways to feel more confident, which limiting beliefs can keep us stuck in our teaching journeys and how accepting our bodies and modelling self-love is an essential part of being an inspiring Yoga teacher.Here are my links:Business coaching: www.amymcdonald.com.au/coachingCounselling: https://www.amymcdonald.com.au/counsellingCoaching training: https://www.amymcdonald.com.au/coachingtraining

Featuring a slide presentation from Dr Matthew Matasar and related discussion from Dr Carla Casulo, Dr Matasar and Dr Laurie H Sehn, including the following topics: Overview of Bispecific Antibodies for the Treatment of Relapsed/Refractory (R/R) Follicular Lymphoma (FL) (0:00) Clinical Data Available with Mosunetuzumab for R/R FL (1:54) Clinical Data Available with Epcoritamab for R/R FL (4:54) Clinical Data Available with Odronextamab for R/R FL (6:53) Clinical Considerations in Selecting Among Available Bispecific Antibodies for R/R FL (8:34) Practical Considerations in the Administration of Bispecific Antibodies (15:21) The Role of Vaccinations in the Prevention of Infections for Patients Receiving Bispecific Antibodies (18:34) Ongoing Clinical Trials Evaluating Bispecific Antibodies for FL (21:34) Case: A man in his late 60s with refractory FL who received mosunetuzumab monotherapy (24:24) Case: A woman in her late 50s with relapsed FL who received third-line epcoritamab monotherapy (30:14) Case: A man in his late 80s with a long-standing history of FL who received odronextamab in combination with a second novel bispecific antibody (33:48) CME information and select publications

Dr Carla Casulo from Wilmot Cancer Institute in Rochester, New York, Dr Matthew Matasar from Rutgers Cancer Institute of New Jersey in New Brunswick and Dr Laurie H Sehn from BC Cancer Centre for Lymphoid Cancer in Vancouver discuss recent updates on available and novel treatment strategies for relapsed/refractory follicular lymphoma. CME information and select publications here.

In this eye-opening episode of The Joe Cohen Show, Joe sits down with microbiologist and biotech entrepreneur Kiran Krishnan to dismantle the myths and marketing hype surrounding microbiome testing. Drawing parallels between the DNA and microbiome industries, they expose the scientific shortcuts, technological flaws, and misleading health claims being sold to consumers.Krishnan, the mind behind one of the few microbiome platforms used in published research, breaks down what a legitimate test looks like and why most tests on the market fall short, sometimes by as much as 70% in accuracy. The conversation also explores probiotics in depth, why strain specificity matters, and how consumers can make more informed decisions when navigating this complex and evolving space.Whether you're a health professional or someone trying to optimize your gut, this episode will help you separate science from sales.

TikTok Flat Earthers; News Items: De-extincting the Dire Wolf, What Experts Think About AI, Planned Obsolescence, VR Touch Sensory; Who's That Noisy; Your Questions and E-mails: SNPs vs Sequencing; Science or Fiction

Dan & Billy welcome back longtime friend & Nostalgia Test Podcast Allstar Jeremy Madson to put Metallica's 90s MTV Era to the ultimate test—THE NOSTALGIA TEST! “We're on the reverse trajectory of Kiss. Right? Because KISS took the makeup off in the nineties and Metallic put it on.” -Jeremy Madson The boys continue the Metallica Eras journey Nostalgia Test Podcast Metalheads with the controversial 90s studio albums The Black Album, Load, & Reload, also known as the MTV era & the Jason Newstead. Dan, Billy, & Jeremy headbang down memory lane and talk about hearing these albums for the first time, the weird transition from the thrash era to whatever this mid-life metal crisis was, the shift in Metallica's musical style, the peculiar cover art for Load & Reload, and production choices. They go track-by-track and create a 10-track merged version of Load & Reload called Unload, which you can listen to here. In the end, the guys rank the 90s era albums.   If you're a Metallica nerd, this episode is for you. If you're not, listen anyway and give it 5-stars. Listen to Unload on Spotify! Email us (thenostalgiatest@gmail.com) ranking so we can share them on the next Metallica episode!    APPROXIMATE RUN OF SHOW: 00:00 Introduction to the Metallica Nostalgia Test 00:37 Recap of Previous Episodes and Albums 01:17 The Nineties Era: MTV and Jason Newstead 01:55 Metallica's Costume Era and Music Videos 03:23 High School Memories and Metallica's Influence 09:26 The Black Album: A Turning Point 19:24 Load and Reload: The Controversial Albums 40:51 Guitar Solos and Bob Rock's Influence 41:58 Debating the Merits of 'Bleeding Me' 42:34 Critiquing 'Cure' and Other Tracks 44:24 Discussing 'Wasting My Hate' 46:38 Country Influences in Metallica's Music 47:11 The Controversial 'Mama Said' 47:46 Evaluating 'Thorn Within' and 'Ronnie' 50:42 The Outlaw Torn and Album Reflection 51:10 Nostalgia Test: Does 'Load' Hold Up? 55:50 Comparing 'Load' to Other Albums of the Era 58:13 Introduction to 'Reload' and Its Reception 58:48 Lead Singles and Album Strategy 01:00:35 Track-by-Track Breakdown of 'Reload' 01:09:32 The Unforgiven II: A Sequel Song 01:13:29 Mixed Reviews on 'Better Than You' and 'Slither' 01:14:56 Debating the Middle Part of the Song 01:15:25 Critiquing the Lyrics and Vocals 01:15:49 Generic Hard Rock and Stoner Rock Comparisons 01:16:39 Discussing 'Where the Wild Things Are' 01:17:05 Lars' Dad's Brutal Honesty 01:17:44 Evaluating 'Prince Charming' 01:18:07 The Unmemorable Riffs 01:20:33 The Irish Bar Drinking Song Vibe 01:21:20 WWE and 'Attitude' 01:21:27 The Lengthy 'Fixer' 01:23:01 Reload Exhaustion and Nostalgia 01:29:50 Ranking and Sequencing the Best Tracks 01:43:45 Final Thoughts and Ranking the Era     Contact/Book The Nostalgia Test Podcast! If you had a great time listening to The Nostalgia Test Podcast and want to book us on your next podcast or have perform at your themed party, or have us host a special event, fill out the form below and LET'S GET NOSTALGIC! We can do so many fun Nostalgic Events! Podcast Guest Appearances Themed Parties Hosting Screenings Corporate Events Reunions Weddings Birthday Parties Trivia The Nostalgia Test Podcast will create a personalized Nostalgic experience for any occasion! Email us at thenostalgiatest@gmail.com or fill out the Google Form below to get the process started. We're open to in-person and virtual events. Pricing may vary depending on the details of your event/party.   LET'S GET NOSTALGIC!       Keep up with all things The Nostalgia Test Podcast on Instagram | Substack | Discord | TikTok | Bluesky | YouTube | Facebook   The intro and outro music ('Neon Attack 80s') is by Emanmusic. The Lithology Brewing ad music ("Red, White, Black, & Blue") is by PEG and the Rejected    

Welcome to another episode of the Oncology Brothers podcast! In this episode, Drs. Rohit and Rahul Gosain are joined by Dr. Aman Chauhan, a medical oncologist specializing in neuroendocrine tumors from Sylvester Comprehensive Cancer Center in Miami. As of April 2025, the oncology landscape has seen 10 new FDA approvals, including the recent approval of cabozantinib for neuroendocrine tumors based on the CABINET study. The discussion dived deep into the implications of this approval, the study design, and how cabozantinib fits into the treatment landscape for both pancreatic and extra-pancreatic neuroendocrine tumors. Key topics covered in this episode include: •⁠  ⁠The evolution of treatment options for neuroendocrine tumors •⁠  ⁠Insights into the CABINET study design and results •⁠  ⁠Sequencing treatment options for patients with neuroendocrine tumors •⁠  ⁠Side effects and management strategies for cabozantinib •⁠  ⁠The importance of personalized treatment approaches in oncology Join us as we explore the exciting advancements in neuroendocrine tumor management and what they mean for patients and oncologists alike. Don't forget to like, subscribe, and check out our other discussions on FDA approvals, toxicity management, and conference highlights! Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ Don't forget to like, subscribe, and hit the notification bell for more updates on oncology insights!

Sequencing with the #1 Virtual Reality Hitting Tool

Send us a textBRAND NEW BOOK - The Daily Bible Devotional Volume 2 (Acts - Ephesians) is now available on Amazon. We hope this becomes a great daily tool in engaging with the New Testament, one chapter at a time. Amazon - (paperback, hardcover, and Kindle)Sponsors:  Jon Cunningham, Owner, Cunningham Financial GroupWebsite:  www.cunninghamfinancialgroup.com   Phone:  205-326-7364Tyler Cain, Senior Loan Officer, Statewide MortgageWebsites: https://statewidemortgage.com/https://tylercain.floify.com/Phone: 813-380-8487Here's the Exercise of the Episode:Answer four questions:- Why are you a Christian?- Why do you go to worship?- Why do you treat everyone with kindness?- Why do you abstain from sexual immorality?First - Answer each question starting with JESUSSecond - Answer each starting with OTHERSFinally - Answer each starting with YOURSELFThis is the way to process and prioritize all we do.Sequencing is Important: J.O.Y.  

Success isn't about tackling every problem at once—it's about mastering the art of sequencing and managing your schedule. Learn how to prioritize effectively, focus on what truly matters, and create a sustainable routine for long-term success.---If you want to level up, text me at 725-527-7783! Get access to our real estate community, coaching, courses, and events at Wealthy University https://www.wealthyuniversity.com/Join our FREE community, weekly calls, and bible studies for Christian entrepreneurs and business people. https://www.wealthykingdom.com/--- ---About Ryan Pineda: Ryan Pineda has been in the real estate industry since 2010 and has invested in over $100,000,000 of real estate. He has completed over 700 flips and wholesales, and he owns over 650 rental units. As an entrepreneur, he has founded seven different businesses that have generated 7-8 figures of revenue. Ryan has amassed over 2 million followers on social media a...

duckDNA recently concluded its second season, which brought continued enthusiasm from hunters and several never-before-seen hybrids! On this episode, Dr. Mike Brasher is joined by conservation science assistants, Kayci Messerly and Katie Tucker, and Dr. Phil Lavretsky to share initial results from season 2 while discussing genetic mysteries uncovered through the analysis of several unique hybrid ducks. Also discussed are behind-the-scenes interactions with participating hunters and the potential future of duckDNA. Thanks to hunters for their support and participation and a special thanks to our year 2 funding partners -- Pinola Conservancy, Rice Pond Preserve, and Brian Hornung.Listen now: www.ducks.org/DUPodcastSend feedback: DUPodcast@ducks.org