In genetics and biochemistry, determining the structure of an unbranched biopolymer
POPULARITY
Categories
Yoga is often perceived as a recovery tool for athletes, but that barely scratches the surface of what yoga can offer active people. In this episode, hosts Tiffany and Rachel explore the many roles yoga can play in athletic cross-training. They discuss how yoga can be used to not only maintain range of motion and provide tools for nervous system recovery, but also to balance repetitive movement patterns and support overall performance. Listen in to learn how cross-training with yoga supports longevity—not just in sports, but in life. Whether you're a runner, cyclist, desk worker, recreational athlete, or parent, incorporating yoga can help you move better, recover more effectively, and continue doing the activities you love for years to come. "As humans, we want to be able to live the full expression of our lives… it really is about optimizing how we feel and function in our lives." — Tiffany Cruikshank. — What You'll Learn: Cross training: the big picture [1:38] How yoga can help [7:23] Cross training and injury reduction [10.51] Sequencing a cross training yoga practice: Breath work, body awareness, isometrics, MFR [12:25] Finding the right level & type of challenge [15:11] Mobility work [16:39] Nervous system regulation [17:45] Active recovery [18:11] Myriad yoga techniques to draw from [19:32] The goals of yoga for cross training: Maintaining mobility and ROM [21:10] Support performance and muscular balance, provide variety [21:58] Nervous system support, rest, and recovery [24:18] Be flexible when teaching yoga cross training classes [26:16] The central goal of cross training: longevity of sport and long-term functionality in life [28:30 Key factors to keep in mind [37:28] The Yoga Medicine Yoga for Athletes Training [41:50] — Links Mentioned: Watch this episode on YouTube Yoga Medicine Yoga for Athletes Teacher Training — Learn More: Find the full show notes at YogaMedicine.com/podcast-162. Learn more about insider tips, online classes or information on our teacher trainings at YogaMedicine.com. To support our work, please leave us a 5 star review with your feedback on iTunes/Apple Podcasts or wherever you listen to podcasts.
Most yoga teachers are taught that sequencing should be creative, complex, and always different. But these common beliefs often making teaching harder -- and keep both teachers and students stuck.Support this show http://supporter.acast.com/yogaland. Hosted on Acast. See acast.com/privacy for more information.
Temu, podvody na sociálnych sieťach, nové pravidlá z Bruselu a Google, ktorý konečne otvoril čiernu skrinku svojich reklám. E-commerce sa mení rýchlejšie než mnohé firmy stíhajú reagovať. Niektoré e-shopy padajú pod tlakom lacného dovozu, inde rastú úplne nové biznis príležitosti, napríklad pánska kozmetika. Do toho sociálne siete zaplavujú scamy a Meta podľa dát umožnila takmer polovicu všetkých autorizovaných podvodov. Znie to drsne, ale práve preto sa oplatí poznať, čo sa v online biznise deje. Viac súvislostí a konkrétnych dát nájdete v našej Mudrovačke za mesiac február.
If you are both lifting weights and doing cardio, is your program optimizing for both without undermining each other?It's not that combining them is bad, but that most people struggle to arrange their training week.Philip walks through the 5 programming mistakes that create interference between your strength training and your conditioning, using the new Velocity 5-day Hybrid program from Physique University as the example of what it looks like when you fix all five.You'll learn when to program your heaviest lifts, which days your sprint intervals should go on, how and when to use a dedicated "active recovery" day, and when to skip the extra conditioning work instead of pushing through it.If you've been trying to build muscle, lose fat, and improve your cardio fitness at the same time and feel like neither one is progressing, this episode will show you where to look first.Cozy Earth bamboo pajamas and blankets | Your training is only as good as your recovery. Cozy Earth's temperature-regulating bamboo pajamas and Classic Cuddle Blanket help you actually rest when you're done for the day. 100-night sleep trial, 10-year warranty. Go to witsandweights.com/cozyearth and use code WITSANDWEIGHTS for up to 20% off.Join Physique University (Velocity + 10 other training templates): physique.witsandweights.comEpisodes MentionedStrength Training and Endurance Together (Without Killing Your Gains)Are Your Fitness Goals in Conflict?Timestamps0:00 - Lifting vs. cardio (does hybrid training create interference?) 4:55 - Mistake 1: Timing of cardio vs. heavy lifts 6:51 - Mistake 2: Superset pairings and muscle fatigue 8:28 - Mistake 3: Putting sprint intervals on the wrong days 10:27 - Mistake 4: To "active recovery" or not? 14:18 - Mistake 5: Doing THIS with every conditioning session 15:45 - Recovery starts with better sleep 17:00 - How the full training week fits together 19:33 - Sequencing vs. exercise selection 20:44 - Velocity 5-Day Hybrid Training program 22:32 - The 60-second hybrid program audit
Commercial Property Finance - Products, Structure and Strategy
In today's episode, Michael talks sequencing your deals to raise finance in the most effective way! You can also watch on YouTube:https://youtu.be/tAYYO1p9v_4▶︎ Website - www.thepropertyfinancecollective.co.uk▶︎ The Host - With a passion for creative finance and the ability to structure deals for Finance, I love helping first time Developers and Investors to get deals packaged for the finance needed to push Property Careers forward, and to date I have raised over £500 million for Developers and Investors. I first got into property at the age of 18 when I got into Conveyancing straight out of school. I then went into Estate Agency, back into Conveyancing and I then got into brokering at the age of 22. I decided a year and a half later that I wanted to work for myself and try and shake up the market place! At the age of 24 I set up The Property Finance Guy and became the youngest owner of a Commercial Finance Brokerage in the Country, and alongside this I now also have a successful Training Company, educating Investor and Developers on how to raise finance, and a successful Podcast.I am a keen public speaker and have delivered training and speeches to over 1000 investors and developers over the past 2 years.Follow Michael:▶︎ Facebook - https://www.facebook.com/thepropfinguy/▶︎ Instagram - https://www.instagram.com/thepropertyfinanceguy/▶︎ LinkedIn - https://www.linkedin.com/in/michael-primrose-886a365b/?originalSubdomain=ukListen to the Podcast on:▶︎ Apple Podcasts - https://podcasts.apple.com/gb/podcast/the-property-finance-podcast/id1448207494▶︎ Spotify - https://open.spotify.com/show/7JiDtm7hc0EfSW9LjCXDaO▶︎ YouTube - https://youtube.com/@thepropertyfinanceguy▶︎ Disclaimer - With the market changing so quickly, the content could be out of date at the time of listening.This Content is for informational purposes only, you should not construe any such information or other material as legal, tax, investment, financial, or other advice.
You said, "That sounds really hard," so why is your partner still upset? It's called the Empathy Dash — that moment you touch your partner's pain just long enough to check a box, then sprint toward solutions, silver linings, or your own experience. In over 1,500 couples sessions, Tony has watched this pattern quietly erode trust while both partners swear they're trying. This episode unpacks why your empathy isn't landing, what your nervous system is actually doing when you rush to fix, and a deceptively simple practice that changes everything. In this episode, you'll discover: Why "me too" on the inside lands like "not you" on the outside — and the intent-vs-impact gap where relationships slowly erode Stealing Thunder: the real-time couples session moment that perfectly captures how sharing gets hijacked before it even lands How your Adaptive Child — the survival strategy that kept you safe growing up — is now sabotaging your closest relationship The neuroscience of co-regulation and why your calm presence does more than your best advice ever could The 3-Before-1 Rule: a concrete practice for staying present when every instinct says fix, solve, or flee Tony Overbay, LMFT, draws from over two decades of couples therapy, Terry Real's relational framework, and Dan Siegel's interpersonal neurobiology to redefine what empathy actually looks like in practice. If you've ever left a conversation thinking "I said all the right things" while your partner felt completely unseen — this one's for you. You're not broken. You just don't know what you don't know yet. 00:00 Welcome and Where to Follow 01:15 Retreat Story Mental Load Misfire 04:56 Intent vs Impact in Bids 06:08 Attack Surface and Pathological Kindness 09:37 Sequencing the Conversation 12:26 Stealing Thunder Named 17:02 Catching the Thunder Grab 18:17 Drive By Empathy Metaphor 21:03 Empathy vs Sympathy Basics 22:36 Why Optimism Can Dismiss 24:02 What Empathy Actually Does 26:58 Real Life Fixing Examples 28:39 Spotting the Empathy Dash 29:30 Why We Do It 30:12 Adaptive Child Origins 31:39 Fixer vs Avoider Examples 33:49 Co-Regulation Explained 34:44 Two Ways to Respond 37:16 Four Pillars Framework 38:11 Questions Before Comments 38:58 Curiosity in Action 42:19 Three Before One Rule 45:40 When Effort Feels Unseen 47:35 Handling Your Triggers 49:27 Closing Encouragement Get on the waitlist today for Tony's upcoming Magnetic Marriage live course! Head to https://tonyoverbay.com/magnetic Contact Tony at contact@tonyoverbay.com to learn more about his Emotional Architects men's group.
EMV Capital (AIM:EMVC, FRA:NTK1) CEO Dr Ilian Iliev and Steve Cook, CEO of EMVC portfolio company DName-iT, talked with Proactive's Stephen Gunnion about advancing safety and accuracy in next-generation DNA sequencing and clinical diagnostics. The discussion focused on the rapid global growth of next-generation sequencing (NGS) in cancer testing, prenatal screening and rare disease identification, and the critical risks that emerge when processing thousands or even millions of samples at scale. Iliev reflected on lessons learned from mass PCR testing during the Covid pandemic, noting how large-scale diagnostics can expose “cracks” in systems, including false positives and false negatives with potentially serious consequences. As sequencing-based testing expands across healthcare systems, eliminating errors becomes increasingly vital. Cook explained how DName-iT addresses these risks by embedding molecular barcodes directly into the testing process. Unlike traditional safeguards such as tube labelling and laboratory protocols, which remain vulnerable to human error, DName-iT introduces patient-specific molecular sequences at the sample level. As Cook described it, the technology builds “quality assurance and safety of these kinds of tests built in at the molecular level.” The company is preparing commercial pilots, having already secured regulatory approvals and manufactured over 500 prepared samples for laboratory trials. Alongside commercialisation efforts in cancer blood testing and prenatal screening markets in the EU and US, DName-iT is also pursuing IP monetisation strategies through potential partnerships. Watch the full interview to learn how EMV Capital is supporting DName-iT's journey toward commercialisation. For more videos like this, visit Proactive's YouTube channel, give this video a like, subscribe to the channel and enable notifications for future content. #EMVCapital #DNameiT #DNATesting #NextGenerationSequencing #NGS #CancerDiagnostics #PrenatalTesting #MolecularBarcoding #HealthcareInnovation #BiotechInvesting #ClinicalDiagnostics #MedTech
In this episode, we're talking about sequencing mistakes - the common ones, the subtle ones, and the ones we definitely made ourselves.Of course, sequencing is subjective. But after years of teaching, training teachers, leading retreats, and building classes that actually retain students, we've noticed patterns. Certain choices tend to create stronger classes, deeper learning, and more trust in the room. And certain habits… quietly work against you.We unpack what happens when you do too much too soon, move too quickly, or walk into class without a clear intention. We talk about over-sequencing one side, changing your class every single week, teaching from ego instead of awareness, and why nervous system regulation matters more than flashy transitions.We also dive into:• Warming up slowly (and why most teachers don't)• Having a plan without being rigid• Simplifying instead of stacking endlessly• Setting a pace that actually matches the breath• Not disorienting your students (they want to feel held, not confused)• Why demoing the entire class might be disconnecting you• How to keep things balanced without overdoing one theme or peakThis episode is honest, practical, and slightly confrontational in the best way. If you're a teacher who wants stronger classes and more grounded students, or a student curious about what's happening behind the scenes, this one's for you.Want to support our podcast? Join our Patreon for extra content** CHECK OUT OUR 300-HOUR PROGRAM **
Episode Summary In this episode of The Wade Borth Podcast, Wade Borth and frequent guest David Zapata recap their experience attending the Nelson Nash Institute Think Tank in Birmingham, Alabama — a gathering of Infinite Banking Concept (IBC) practitioners focused on preserving Nelson Nash's legacy and advancing financial education. Rather than discussing tactics alone, the conversation explores deeper themes revealed during the event: the human side of money, the importance of community, and why both financial professionals and clients struggle with the same three core challenges — loneliness, lack of systems, and absence of guidance. Wade and David unpack how Infinite Banking is not merely a financial product but a long-term transformation process centered on mindset, behavior, and intentional growth. The episode highlights the Think Tank's central theme — "Think Long Range" — and explains why wealth building requires decades-long thinking, clarity of purpose, and continuous personal development. Listeners will gain insight into how financial strategies serve as tools — not goals — and why becoming your own banker is ultimately about becoming a more intentional leader in your financial life, family, and community. Links & Resources Connect with David Z - Infinite Banking Foundations or at davidzapata@factumfinancial.com Connect with Wade - Infinite Banking Foundations or at wade@factumfinancial.com *Can we attach this as a pdf? - and note if anyone wants the video accompanying the attached PDF, they should contact David Zhttps://18. LIQUIDITY STRATEGY (1).pdf Keywords Infinite Banking Concept Nelson Nash Institute Think Long Range Becoming Your Own Banker Financial mindset Wealth building philosophy Liquidity strategy Whole life insurance strategy Community and coaching Financial education Private banking strategy Human behavior and money Financial leadership Long-term thinking Generational wealth Financial systems and processes Personal development Wealth psychology Financial independence Money mindset transformation Episode Highlights 00:10–01:17 - Introduction and purpose of the Nelson Nash Institute recap 01:17–03:01 - What the Think Tank is and why practitioners gather annually 03:01–04:55 - Community vs. groupthink: learning through diverse perspectives 04:55–07:07 - Infinite Banking as mindset, process, and properly structured product 07:07–08:44 - Two conversations happening simultaneously: professionals and clients 08:44–10:32 - Liquidity as the root financial problem most people face 10:32–13:19 - The three shared pains of agents and clients: loneliness, systems, guidance 13:19–15:11 - Human behavior as the true obstacle in financial success 15:11–18:17 - Why coaching and community accelerate financial confidence 18:17–21:17 - "Think Long Range" and the transformation behind becoming your own banker 21:17–24:51 - Long-term relationships vs transactional financial advice 24:51–26:59 - Generational thinking and building financial foundations that last decades 26:59–28:48 - Infinite Banking as a bridge to life goals — not the goal itself 28:48–31:01 - Focusing on vision instead of financial tools and mechanics 31:01–34:10 - Personal reflections and growth through industry experience 34:10–36:28 - Improving client conversations through empathy and curiosity 36:28–38:18 - Confirming progress while recognizing room for growth 38:18–41:04 - Sequencing financial decisions and avoiding premature strategies 41:04–44:44 - Final takeaway: becoming the "chess master" of your financial life
I see teams struggle with the flow of value because they are either bogged down in the stories and tasks or they don't have a candle in the dark room.Hey Product Owner, you have to light that candle and show them the way.If prioritization seems like a never-ending battle or even worse you are prioritizing the wrong backlog - yes - you know the one...Then this episode is for you!This episode is great for product owners, new and old. But not just for you! Agile leaders, scrum masters, dev teams and project managers could probably steal some things from this one.Kickin it old school on this one!www.planetproductowner.org is being updated.The tests are over. Coming soon!!
On this week's podcast, Jason outlines why the old models of yoga sequencing are no longer effective in today's landscape. To name a few: More people cross-train. Fewer students are walking into studios. ClassPass has changed loyalty. Online platforms have shifted expectations. If you want better student retention, stronger engagement, and a more sustainable yoga teaching career, this conversation is essential.⸻⏱ Highlights2:23 Sequencing 2.0 — What's New6:00 The Two Traditional Sequencing Models6:57 The Problem with Fixed Sequences8:07 The Problem with Random Classes13:29 Why Student Retention Is Harder Now20:39 Online Teaching & Retention29:50 ClassPass & (the lack of) Loyalty35:19 The Solution: Monthly Progressions35:33 How to Build Skill Over Time⸻Jason shares why consistency and novelty must coexist, how to use month-long progressions, how to think like an educator, and how we can help students build skills, helping to build student retention. to maintain retention. If you're serious about becoming a more effective and modern yoga teacher, it's a must-listen! Hosted on Acast. See acast.com/privacy for more information.
You track your food. You lift. You can explain why protein matters for building muscle. So why hasn't your body changed? The gap between knowing what to do and getting results is not a discipline problem. It's a structure problem. And more nutrition and fitness information won't fix it.Philip breaks down what's actually missing for experienced lifters over 40 who have tried multiple programs and still feel stuck. Drawing intake data from hundreds of coaching clients, he explains why conflicting advice creates rational paralysis, why 49% of knowledgeable lifters still struggle with the basics, and the 3 specific things (sequencing, context, and feedback loops) that separate people who know what to do from people who get results. He also covers why this gap hits harder after 40, when hormonal shifts from perimenopause, menopause, and declining testosterone shrink the margin for error on both strength training and nutrition.If you've been doing "all the right things" and your body composition hasn't budged, this episode will reframe what's actually standing in your way, and what an effective solution looks like.Join the Eat More Lift Heavy waitlist to be the first to hear about a brand new structured asynchronous coaching process built for experienced lifters who have the knowledge but need sequencing, context, and feedback loops to finally close the gap between knowing and doing:https://witsandweights.com/eatmoreTimestamps0:00 - Knowing vs. doing (the real reason you're stuck) 2:02 - The information trap in nutrition and fitness 6:45 - Conflicting advice and analysis paralysis 11:25 - What's actually missing (it's not discipline) 14:30 - Sequencing: why 1 change per week beats 50 19:10 - Why generic plans fail lifters over 40 23:20 - Building feedback loops for your training and nutrition 27:10 - Structured asynchronous coaching 28:30 - What good coaching actually looks like 36:20 - The middle ground that barely exists in fitness
In today's episode, we welcomed Quinto Gesiotto, MD, a malignant hematologist at Tampa General Hospital in Florida.In the exclusive interview, Dr Gesiotto explored the evolving role of TKIs in the treatment of patients with chronic myeloid leukemia (CML), including dosing patterns for ponatinib (Iclusig) in those with CML and other TKI data to emerge in the CML space at the 2025 ASH Annual Meeting and Exposition. Dr Gesiotto also provided detail on emerging data on novel strategies and agents, along with genetic mutations beyond BCR-ABL1 T315I the could drive more personalized treatment sequencing and improved risk stratification in CML in the future.
In this episode of the Pediatric and Developmental Pathology, our hosts Dr. Mike Arnold (@MArnold_PedPath) and Dr. Jason Wang speak with Dr. Aida Glembocki, a Pediatric Pathologist and Masters Degree candidate at the University of Toronto, and Dr. Robert Siddaway, an Oncology Investigator at The Hospital for Sick Children in Toronto. Hear about how The Hospital for Sick Children applies RNA sequencing in pediatric cancer diagnosis to reduce costs and identify key information for diagnostic classification. We also hear about their article in Pediatric and Developmental Pathology: Fusion-Negative Rhabdomyosarcoma: Clinical Application of Targeted RNA Sequencing Related article: Siddaway R, Glembocki AI, Arnoldo A, Staunton J, Liu APY, Yuki KE, Yu M, Cohen-Gogo S, Shlien A, Villani A, Whitlock JA, Hitzler J, Tabori U, Levine AB, Lafrenière A, Nagy A, Chen H, Ngan BY, Somers GR, Abdelhaleem M, Chami R, Hawkins C. Clinical utility of targeted RNA sequencing in cancer molecular diagnostics. Nat Med. 2025 Oct;31(10):3524-3533. doi: 10.1038/s41591-025-03848-8. Epub 2025 Jul 17. PMID: 40676318. Featured public domain music: Summer Pride by Loyalty Freak
The City Bar's Presidential Task Force on AI and Digital Technologies hosts today's podcast on President Trump's: Winning the Race, America's AI Action Plan. Task Force co-chair Jerome Walker is joined by task force members Matthew Bacal (Davis Polk), Azish Filabi (American College of Financial Services), Robert Mahari (Stanford Codex), and Evan Abrams (Steptoe), to review the plan's three pillars and key action steps. Pillar One (“Accelerate AI Innovation”) is described as largely deregulatory, including agency review of rules and certain FTC/FCC actions, with targeted concerns such as ideological bias and synthetic media in the legal system, plus investments in open-source/open-weight models, data, interpretability, evaluations, and government/DoD adoption. Pillar Two (“Build American AI Infrastructure”) focuses on the physical side of AI—permitting for data centers and fabs, energy and grid expansion, semiconductors, water for cooling, workforce training, cybersecurity, and “security by design,” while anticipating trade-offs and litigation. Pillar Three (“Lead in International AI Diplomacy and Security”) balances support for exporting US “full stack” AI with tighter national security controls, including stronger export-control enforcement and participation in international bodies primarily to counter China. The conversation closes with suggestions for improving the plan by strengthening trust, safety/rights considerations, and maintaining flexibility as AI capabilities evolve. If you are interested in learning more about emerging AI developments and policy, join us for the 2026 Artificial Intelligence Conference on June 18 to hear from industry experts and connect with leading legal professionals across the field. 00:00 Trump's 2025 AI Action Plan: Big Goals, Short Document, 3 Pillars 03:23 Pillar One Preview: 15 Action Steps to ‘Accelerate AI Innovation' 09:16 Meet the Panel + Setting Up the Pillar One Deep Dive 11:21 Pillar One Explained: Deregulation, Free Speech, Data Sharing, Evaluations, and Trust 18:33 Key Takeaways for Stakeholders: Business, Finance, Civil Society, and Tech 23:57 Which Pillar One Steps Matter Most? Sequencing, Competitiveness, and Data Access 27:52 Pillar Two: The Physical Side of AI—Energy, Chips, Data Centers 36:32 Critical Infrastructure Security: Physical Risks, Cyber Threats & ‘Security by Design' 37:14 Data Poisoning Explained: How Training Data Can Be Manipulated at Scale 38:00 Workforce Training at Scale: From Trades to Semiconductor Talent Pipelines 38:52 Wrapping Pillar Two: China Competition, Speeding Projects, and Ranking Priorities 40:34 What Lawyers & Judges Need to Know About Pillar Two (Red Tape, Legal Tech, Litigation) 45:30 Pillar Three Overview: Balancing Global AI Leadership with National Security Controls 50:05 Pillar Three Priorities by Industry: Export Controls, Frontier Evaluations & Data Center Risk 58:56 Why Engage International AI Bodies? Countering China and Filling the Leadership Vacuum 01:03:20 Trump vs. Biden Narratives: Competition vs. Safety—What Should Change in the Plan? 01:07:38 Panel Advice to Improve the Action Plan: Rights Framework, Nimble Policy, Safety & Research Funding
Welcome to the Health Marketing Collective, where strong leadership meets marketing excellence.On today's episode, Carrie Maurer joins host Sara Payne for a candid exploration of marketing's impact in complex B2B environments where buying cycles are long, decisions are high stakes, and the revenue impact of marketing matters more than ever. With over 25 years as a CMO and growth leader working alongside CEOs in large enterprises, high-growth companies, and startups, Carrie is uniquely positioned to offer a real-world perspective on how marketing can—and must—operate as a genuine driver of revenue in regulated, highly complex industries.The episode is anchored around one crucial question: If marketing disappeared tomorrow, would revenue actually suffer? Together, Sara and Carrie dig into what it means for marketing to be accountable to revenue, as opposed to simply activity or awareness metrics. They explore how marketing's influence goes beyond campaigns or messaging, and instead is about aligning strategy, operations, and storytelling so that growth can happen.Carrie brings clarity to the often-overlooked design problems that prevent marketing from impacting revenue, emphasizing the importance of leadership decisions, system design, and cross-functional accountability. The conversation moves from practical signals of marketing's real impact—like buyer momentum and internal champion empowerment—to the nuances of strategic partnership between sales and marketing, and the discipline of sequencing growth activities. Rounding out the episode, Sara and Carrie discuss the value of patience as a strategic advantage and the critical need for marketing to measure and influence decision movement, not just attention.Thank you for joining the Health Marketing Collective, where strong leadership meets marketing excellence. The future of B2B marketing depends on it.Key Takeaways:Marketing's True Accountability Is to Revenue, Not ActivityCarrie challenges marketing leaders to reconsider what they measure. Activity metrics—like campaign impressions, downloads, or event attendance—are visible and controllable, but they signal motion, not movement. The real test of marketing's impact is whether it drives revenue by helping decisions progress within the buyer's and seller's organizations.Design Problems Need Leadership Decisions and System AlignmentIf marketing's absence wouldn't affect revenue, it's not a failure of people but a sign that marketing hasn't been designed to influence where decisions are made. Fixing this requires leadership choices around scope, structure, priorities, and operating models—not just more marketing effort.Strategic Partnership Between Sales and Marketing Is EssentialFor marketing to have a revenue impact, it must sit at the strategic table with sales, product, and operations. When marketing has commercial fluency—understanding the product, competitive landscape, buyer environment, and internal business case dynamics—it strengthens sales teams, empowers internal champions, and helps navigate complexities that stall high-stakes decisions.Sequencing and Patience Are Strategic Advantages in B2B GrowthIn complex sales cycles, the discipline of sequencing—guiding both buyer and seller
On this episode of Data Dump, we break down the numbers behind Tomoyuki Sugano and José Quintana — and what the data says about their 2026 outlook.Recorded on 2/11/26Sugano arrives with elite command, pitchability, and years of dominance overseas. But how does his arsenal translate? We dive into his pitch mix, strike-throwing profile, whiff rates, and what comparable MLB arms tell us about his ceiling at altitude.Quintana, meanwhile, continues to defy aging curves. Is it smoke and mirrors? Soft contact mastery? Sequencing? We analyze his underlying metrics — K-BB%, ground ball rate, contact quality, and road/home splits — to determine whether his success is sustainable or regression-bound.Subscribe for weekly Rockies analytics breakdowns.#ColoradoRockies #DataDump #TomoyukiSugano #JoseQuintana #MLBAnalytics #RockiesBaseball #BlakeStreetBanter
We visit Plasmidsaurus and spoke with CEO Mark Budde about why they are offering sequencing for so cheap, what surprises came up when their customers first got whole plasmid sequencing, and how sequencers are like bread machines. Join the discussion in the comments on YouTube: https://youtu.be/Ss8H6VUQBGo Where to find us online: https://omgenomics.com
In this part 2 of a 4-part podcast series, you'll discover more of what builds confident yoga teaching. It's a combination of having a solid approach to cueing, sequencing, to understanding the fundamentals of anatomy and having a confident mindset. In today's episode, you'll hear about a sequencing approach that will help you feel more confident in the sequence you offer, take less time to prepare for your classes and allow you to stand out as a yoga teacher: I mention a training video that shares more on sequencing and you can get that here: https://barebonesyoga.lpages.co/how-to-create-a-signature-sequence/ If you're curious about the training program I mentioned, you can check out my program here: https://barebonesyoga.thinkific.com/courses/Yoga-Anatomy-Accelerator
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/CTJ865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 6, 2027.Key Steps to Success With CDK4/6 Inhibition in Early Through Metastatic Breast Cancer: Stratification, Selection, Sequencing, and Specialty Management In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Living Beyond Breast Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Lilly and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/CTJ865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 6, 2027.Key Steps to Success With CDK4/6 Inhibition in Early Through Metastatic Breast Cancer: Stratification, Selection, Sequencing, and Specialty Management In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Living Beyond Breast Cancer. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by educational grants from Lilly and Novartis Pharmaceuticals Corporation.Disclosure information is available at the beginning of the video presentation.
Drs. Coombs and Danilov explore how to optimally sequence covalent BTK inhibitors, non‑covalent BTK inhibitors (such as pirtobrutinib), and venetoclax-based regimens for relapsed CLL, emphasizing real-world data and emerging trial results. They highlight that treatment choices hinge on prior response depth and duration, tolerability, mutational profile, and the need to preserve future options and clinical trial eligibility.
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
CARTA - Center for Academic Research and Training in Anthropogeny (Video)
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
Dramatic advances in ancient DNA technologies have revolutionized our understanding of the human past. As part of the CARTA symposium on Ancient DNA, the panelists answer questions about the diverse applications of archaeogenomics in shaping not only a new vision of the human past, but also in creating a greater understanding of the present and our shared human future. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41202]
Sequencing doesn't start with themes or peak poses, it starts with understanding the pose itself. In this episode, I introduce pose literacy and explain why it's the missing link behind clearer, safer, and more intelligent sequencing. Using Downward-Facing Dog as a real example, I break down how learning to read a pose beyond alignment can completely change how you teach, sequence, and support your students.Episode Highlights:Why modern sequencing often skips the most essential stepWhat pose literacy is, and why alignment alone isn't enoughHow low pose literacy leads to guesswork, overload, and unsafe sequencingA pose-literacy breakdown of Downward-Facing DogHow a pose-first approach transforms sequencing and teaching confidenceWaitlist for the Online 300-Hour Yoga Teacher Training (launching January)Sequence Smarter – The Living Body of AsanaFor teachers living in India, reach out to Janessa at admin@ahamyoga.com for special local pricingJoin our mailing listFind all the resources mentioned in this episodeConnect with us on Instagram
Host: Jennifer Caudle, DO, FACOFP Guest: Mansi R. Shah, MD The latest International Myeloma Working Group (IMWG) guidelines emphasize immune function, relapse timing, and therapeutic intent to guide the sequencing of T-cell-redirecting therapies in relapsed/refractory (R/R) multiple myeloma. Hear key updates as Dr. Jennifer Caudle and Dr. Mansi Shah discuss how we can integrate T-cell redirecting therapies into patient care more intentionally. Dr. Shah is an Associate Professor and the Clinical Director of Multiple Myeloma at the Rutgers Cancer Institute.
This episode breaks down a key 2026 initiative: when and how to diversify your media mix, grounded in real operator decision-making rather than theory. The conversation uses HexClad's approach as a case study, exploring the data signals that indicate it's time to expand channels, how teams test incrementality, and how operators manage rising measurement complexity - especially when scaling internationally.Along the way, the team explains how the “Rocks” system supports this kind of decision-making, from setting clear priorities and aligning teams to establishing cadence and ownership. They also unpack how KPIs are chosen at different stages, how retention-focused Rocks anchor growth efforts, and how insights from Japanese market data inform smarter media mix expansion.If you have a question for the MOperators Hotline, click the link to be in with a chance of it being discussed on the show: https://forms.gle/1W7nKoNK5Zakm1Xv6Chapters:00:00:00 - Introduction00:03:27 - Hexclad's 2026 Rocks00:23:08 - Signals for Channel Expansion00:32:23 - Expansion Playbook & Strategy00:43:17 - New US Channels00:55:59 - Sequencing & ComplexityPowered by:Motion.https://motionapp.com/pricing?utm_source=marketing-operators-podcast&utm_medium=paidsponsor&utm_campaign=march-2024-ad-readshttps://motionapp.com/creative-trendsRivo.https://www.rivo.io/operatorsPrescient AI.https://www.prescientai.com/operatorsRichpanel.https://www.richpanel.com/?utm_source=MO&utm_medium=podcast&utm_campaign=ytdescAftersell.https://www.aftersell.com/operatorsSubscribe to the 9 Operators Podcast here:https://www.youtube.com/@Operators9Subscribe to the Finance Operators Podcast here:https://www.youtube.com/@FinanceOperatorsFOPSSign up to the 9 Operators newsletter here:https://9operators.com/
Episode Description:This second installment of “From the Archive” returns to James's early, unfiltered conversation with Tim Ferriss. They unpack how to market by creating newsworthy moments (including a frigid book-launch fiasco turned lesson), how to learn anything using Tim's DISS framework (Deconstruction, Selection, Sequencing, Stakes), and why “possibility is negotiable” when you seek outliers and test assumptions. Tim explains fear-setting, slow-play networking that leads to real mentors, and the origin story of BrainQUICKEN → BodyQuick, including direct-response tactics, offline ads, and early UFC sponsorships. The through-line: run small experiments, protect your best energy, and stack skills to raise your odds.What You'll Learn:How to engineer “newsworthy” launches and recover from execution misses without losing momentum.The DISS method for rapid learning (Deconstruction, Selection, Sequencing, Stakes) you can apply to languages, poker, orFear-setting, not goal-setting: define worst-case scenarios, prevention steps, and recovery plans to make bolder moves.Mentors without asking “be my mentor”: add value first, build loose ties, and let a few relationships compound.From side-hustle to exit: repositioning, channel selection (including print/radio), and why out-of-fashion inventory can be a bargain.Timestamped Chapters:[02:20] A launch-day disaster in 10° weather—and the customer-recovery playbook.[05:00] “Possibility is negotiable” vs. the default “probable” path.[06:57] Finding mentors by learning before earning: the slow-play relationship strategy.[10:00] Optionality: the angel-investing analogy for career and mentors.[14:00] The DISS framework for learning anything.[18:50] Hunt the outliers: why “who shouldn't be good at this—but is?” unlocks technique.[24:30] Fear-setting: risk = likelihood of an irreversible negative outcome.[26:20] Micro-experiments to de-risk big transitions.[27:24] Secret origin: BrainQUICKEN → BodyQuick; from nootropics to non-stimulant pre-workout.[31:55] Repositioning, targeted niches, and early UFC placements.[33:13] Don't ignore “old” channels: print and radio as arbitrage.[33:55] Burnout, one-way ticket to London, and systems that led to a sale.[40:36] Title testing (and red herrings) in publishing.[46:16] The 4-Hour Workweek started by accident [52:14] Publishing myths: how “impossible” ideas become inevitable [01:07:58] TV vs. podcasting: control, constraints, and creative freedom [01:31:34] Investing: bet on people (the beer test + mall test) Additional Resources:Tim Ferriss — official site/podcast hub: tim.blog • The Tim Ferriss ShowThe 4-Hour Workweek (Expanded & Updated): Amazon listingThe 4-Hour Body — official site: fourhourbody.comThe 4-Hour Chef — official site: fourhourchef.comThe 4-Hour Workweek — official site: fourhourworkweek.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of The Light inside, The discussion centered on Jeffrey Besecker's extensive experiences and insights related to trauma recovery, identity, and therapeutic practices. Besecker highlighted the importance of safety and coherence in the recovery process, noting that individuals often struggle with feelings of threat that can hinder their progress. He introduced the concept of double loop learning as a framework for adapting to experiences and emphasized the significance of pacing and sequencing in therapeutic interventions. The conversation aimed to explore how community support and individual experiences can enhance the healing journey.Mike Cuevas shared his personal journey with dissociative identity disorder (DID), detailing the impact of misdiagnosis and the challenges he faced in understanding his identity. He recounted how silence became a coping mechanism during his formative years, leading to feelings of shame. The discussion underscored the need for a coherent approach to integrating insights about DID with the body's capacity to process those insights, emphasizing the importance of creating a safe therapeutic space for effective healing.The conversation also delved into the role of the practitioner's state of mind and co-regulation in therapy. A conference room participant shared personal experiences and the development of mental exercises to manage emotional triggers, introducing the BAR technique as a tool for emotional regulation. Besecker and Mike explored the significance of recognizing bodily sensations in differentiating identity states, which can lead to greater clarity and peace. They discussed the transformative power of empathy in processing past traumas and the importance of adaptive containment in therapeutic relationships.Mike reflected on how his personal development has influenced his parenting, particularly in managing stressful situations with his children. He shared an incident where he maintained calmness during a confrontation, demonstrating the value of mindfulness and emotional regulation. The discussion concluded with Besecker expressing gratitude for Mike's insights and the potential for future collaborations, highlighting the unique and revelatory nature of their conversation.Time Stamps00:00:00 - Introduction to Coherence and DID00:01:13 - Sponsor Message: Mint Mobile00:02:27 - Understanding Dissociative Identity Disorder00:03:10 - Mike Cuevas Joins the Conversation00:04:11 - Early Signs of Dissociation00:05:26 - Insight vs. Capacity00:06:38 - Adaptive Coping Patterns00:07:43 - Shame and Guilt in Misdiagnosis.00:09:09 - Therapeutic Journey Begins00:10:24 - Boxing as a Therapeutic Outlet00:12:03 - Stigmatization and Adaptive Survival00:13:07 - Pacing and Sequencing in Therapy00:14:38 - Visceral Trauma and Sensory Overload00:16:47 - Connecting Boxing to Somatic Responses00:18:46 - Learning to Feel Safe00:20:19 - Somatic Attunement and Sensory Perception00:22:05 - The B.A.R. Technique00:24:45 - Double Loop Learning00:26:11 - Identifying Distinct Identity Stateslf.00:28:20 - Chaos as Opportunity00:30:11 - Empathy vs. Sympathy00:32:49 - Claiming Sovereignty00:35:04 - Adaptive Containment00:39:10 - Presence and Capacity00:41:05 - Body Assigns Meaning00:50:34 - The Role of Pause in ProcessingCreditsHost: Jeffrey BeseckerGuest: Mike CuevasExecutive Program Director: Anna GetzProduction Team: Aloft Media GroupMusic: Courtesy of Aloft Media GroupConnect with host Jeffrey Besecker on LinkedIn.
A deep dive into yoga sequencing, what it actually is, why it matters, and the most common mistakes yoga teachers make when planning classes, I break down the difference between choreography and intentional sequencing, explore the role of the pranic and nervous systems, and share nine sequencing missteps to avoid for safer, smarter, and more sustainable teaching. This episode is especially relevant for yoga teachers who want to build confidence, longevity, and depth in their classes.Episode Highlights:What is sequencingWhy sequencing is a skill, not a formulaWhat yoga sequencing truly means beyond pose choreographyHow thoughtful sequencing supports safety, longevity, and nervous system regulationThe role of structure, progression, intention, and integration in class planningWhy sequencing shapes the energetic and pranic arc of a classHow intelligent sequencing builds trust, confidence, and professional credibilityThe 9 Sequencing Mistakes to Avoid:Treating sequencing as simply linking poses togetherOver-focusing on peak poses at the expense of purposeSkipping joint preparation and intelligent warm-upsOverloading classes with too many posesNeglecting counter-poses and proper class closureDesigning sequences based on personal preference instead of student needsIgnoring the energetic arc and pranic systemForcing philosophy or over-theming without embodimentFailing to teach toward longevity and sustainable practiceWaitlist for the Online 300-Hour Yoga Teacher Training (launching January)Sequence Smarter – The Living Body of AsanaFor teachers living in India, reach out to Janessa at admin@ahamyoga.com for special local pricingJoin our mailing listFind all the resources mentioned in this episodeConnect with us on Instagram
Featuring perspectives from Prof Giuseppe Curigliano, Prof Nadia Harbeck, Dr Ian E Krop, Dr Nancy U Lin and Dr Joyce O'Shaughnessy, including the following topics: Introduction (0:00) Considerations in the Care of Patients with Localized HER2-Positive Breast Cancer — Prof Harbeck (1:39) Case: A woman in her mid 50s presents with locally advanced ER-positive, HER2-positive breast cancer — Alan B Astrow, MD (12:52) Case: A woman in her mid 40s with ER-positive, HER2-positive Stage II breast cancer s/p neoadjuvant TCHP with residual disease receives adjuvant T-DM1 but discontinues due to neuropathy — Laila Agrawal, MD (20:02) Previously Untreated HER2-Positive Metastatic Breast Cancer (mBC) — Prof Curigliano (25:10) Case: A woman in her early 80s presents with de novo metastatic (bone-only) ER-positive, HER2-positive breast cancer — Zanetta S Lamar, MD (35:03) Optimal Management of Brain Metastases in Patients with HER2-Positive Breast Cancer — Dr Lin (46:20) Case: A woman in her early 60s with ER-positive, HER2-positive breast cancer develops a cerebellar metastasis while receiving adjuvant anastrozole after prior anti-HER2 therapy — Justin Favaro, MD, PhD (59:41) Case: A woman in her early 40s with ER-negative, HER2-positive mBC develops a headache shortly after neoadjuvant TCHP, surgery and postneoadjuvant T-DM1 and is found to have an isolated 4-cm brain metastasis — Dr Agrawal (1:05:36) Selection and Sequencing of Therapy for Relapsed/Refractory HER2-Positive mBC in the Absence of CNS Involvement — Dr Krop (1:12:00) Case: A woman in her early 40s with ER-positive, HER2-positive mBC receives THP (docetaxel/trastuzumab/pertuzumab) and maintenance tucatinib with trastuzumab/pertuzumab on a clinical trial and now has disease progression — Yanjun Ma, MD, PhD (1:23:04) Tolerability Considerations with HER2-Targeted Therapies — Dr O'Shaughnessy (1:29:32) Case: A woman in her mid 60s presents with localized ER-negative, HER2-positive infiltrating ductal carcinoma — Erik Rupard, MD (1:46:06) Case: A woman in her early 70s with recurrent ER-positive, HER2-positive mBC receives trastuzumab deruxtecan (T-DXd) and has concerning pulmonary symptoms but without findings on diagnostic imaging — Kimberly Ku, MD Case: A woman in her mid 40s with ER-positive, HER2-positive breast cancer metastatic to the brain and lung who received multiple prior treatments responds to T-DXd but develops Grade 1 interstitial lung disease — Richard Zelkowitz, MD (1:49:49) CME information and select publications
Sequencing goals are common in IEPs, but do they actually lead to meaningful outcomes? In this episode, I share why I no longer write traditional sequencing goals and what I do instead to support generalization, comprehension, and real-world language use. We'll look at how isolated sequencing tasks fall short and how embedding sequencing within narrative-based therapy can better support students' communication skills.In this episode, you'll learn:Why decontextualized sequencing tasks often don't generalizeHow narrative-based frameworks support sequencing, memory, and comprehensionExamples of functional, measurable alternatives to traditional sequencing goalsPractical ways to scaffold sequencing within real stories and experiencesListen in to rethink how you target sequencing and walk away with ideas you can apply in therapy right away.
We revisit 2025's defining themes, and discuss why ‘sequencing' - timing entries and exits around range bound rate moves and curve shape rather than level - matters as markets stabilize and growth re-accelerates.
Featuring perspectives from Dr Javier Cortés, Dr Rita Nanda, Prof Peter Schmid and Dr Priyanka Sharma, including the following topics: Introduction (0:00) Case: A woman in her early 80s with multiple comorbidities and triple-negative breast cancer (TNBC) develops bone-only metastases 4 months after declining capecitabine for post-neoadjuvant residual disease — Justin Favaro, MD, PhD (1:50) Case: A woman in her mid 70s with ER-negative, HER2-low (IHC 1+), PIK3CA-mutated, PD-L1-positive metastatic breast cancer (mBC) after receiving 3 cycles of neoadjuvant paclitaxel/carboplatin/pembrolizumab, which was discontinued — Alan Astrow, MD (6:47) Previously Untreated Metastatic TNBC (mTNBC) — Prof Schmid (10:47) Case: A woman in her early 80s with multiregimen-recurrent ER-positive, HER2-low (IHC 1+) ESR1-mutant mBC receives sacituzumab govitecan — Jennifer Yannucci, MD (27:19) Case: The role of datopotamab deruxtecan (Dato-DXd) for patients with ER-positive, HER2-low mBC who experienced disease progression on prior trastuzumab deruxtecan (T-DXd) — Ranju Gupta, MD; Case: A woman in her late 70s with bilateral recurrence in the lungs of ER-negative, HER2-low (IHC 1+) breast cancer (PD-L1 TPS 20%) receives Dato-DXd with durvalumab on protocol — Yanjun Ma, MD, PhD (31:35) Integrating Antibody-Drug Conjugates (ADCs) into the Management of Endocrine-Resistant Hormone Receptor-Positive mBC — Dr Sharma (36:31) Case: A woman in her early 70s with recurrent ER-negative, HER2-low (IHC 2+) mBC receives sacituzumab govitecan and achieves complete remission — Dr Gupta; Case: Management of neutropenia associated with sacituzumab govitecan — Gigi Chen, MD (50:30) Case: A woman in her late 60s with recurrent ER-negative, HER2-low (IHC 1+) mBC (HER2 V69L mutation) receives T-DXd and achieves a complete response but develops Grade 1 interstitial lung disease — Dr Gupta; Case: Management of T-DXd-related side effects — Laila Agrawal, MD (54:10) Selection and Sequencing of Therapy for Relapsed/Refractory mTNBC — Dr Nanda (58:59) Case: A woman in her early 40s with multiregimen-recurrent ER-positive, HER2-low mBC who has experienced severe nausea with past treatments is about to initiate T-DXd — Atif M Hussein, MD, MMM (1:12:40) Tolerability and Other Practical Considerations with ADCs and Other Cytotoxic Agents for mBC — Dr Cortés (1:18:10) CME information and select publications
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Wei-Wu, Executive Chairman at Human Longevity, Inc. Together, they explore how advances in genome sequencing, AI, and multi-layered diagnostics are changing the fight against age-related diseases. Wei-Wu shares why understanding your own genetic risks and combining them with other health data leads to better prevention and a longer healthspan.Wei-Wu explains the value of integrating genome sequencing, advanced imaging, and liquid biopsy to catch diseases like cancer early, before symptoms appear. He draws on real-world examples, including how combining different tests can spot cancers that single methods might miss. The conversation highlights how technology brings down costs, making once-rare insights widely available, and how each person stands to benefit from personalized risk profiles.The episode closes with practical advice: use today's tools to become the CEO of your own health. Wei-Wu urges listeners to embrace data-driven, individualized care and stresses that no single tool or habit holds all the answers. Instead, true longevity comes from a holistic, ongoing approach, one that uses all available knowledge to prevent disease and extend both life and health.Guest-at-a-Glance
Featuring perspectives from Dr Matthew S Davids, Dr Bita Fakhri, Prof Constantine Tam and Dr Jennifer Woyach, including the following topics: Introduction (0:00) Current and Emerging Approaches to First-Line Therapy for Chronic Lymphocytic Leukemia (CLL) — Dr Davids (1:42) Case: A man in his mid 70s with a plethora of comorbidities but good performance status requires treatment for CLL — Bhavana (Tina) Bhatnagar, DO (14:58) Case: A man in his early 50s, a Jehovah's Witness, under observation for IGHV-mutated CLL develops pulmonary emboli and worsening lymphadenopathy, undergoes anticoagulation and begins therapy with zanubrutinib — Jennifer Yannucci, MD Case: A man in his mid 70s with a history of atrial fibrillation on apixaban receives zanubrutinib — Zanetta S Lamar, MD (22:30) Optimal Management of Adverse Events with Bruton Tyrosine Kinase and Bcl-2 Inhibitors; Considerations for Special Patient Populations — Prof Tam (32:50) Case: A man in his mid 90s with CLL has concurrent locally advanced Merkel cell carcinoma of the scalp — Erik Rupard, MD (50:51) Case: A woman in her early 50s under observation for IGHV-unmutated CLL develops progressive splenomegaly and receives obinutuzumab/venetoclax — Sean Warsch, MD (54:28) Selection and Sequencing of Therapy for Relapsed/Refractory CLL — Dr Woyach (1:05:51) Case: A man in his mid 70s with high-risk (del[TP53]) CLL experiences disease progression on ibrutinib and then venetoclax/obinutuzumab — Dr Bhatnagar (1:27:23) Case: A man in his early 80s with IGHV-unmutated CLL who previously received FCR now experiences disease relapse after 5 years of acalabrutinib, and a BTK C481S resistance mutation is detected — Priya Rudolph, MD, PhD (1:29:34) Chimeric Antigen Receptor T-Cell Therapy and Other Novel Strategies for CLL — Dr Fakhri (1:34:08) Case: A man in his early 70s with multiregimen-relapsed CLL experiences an 18-month response to pirtobrutinib — Brian P Mulherin, MD (1:50:46) CME information and select publications
James Clear is an expert on behavioral change and habits and the author of the bestselling book Atomic Habits. We discuss the best ways to build new healthy habits and end bad ones without relying on motivation or willpower. Rather than list off categories of tools or acronyms, James explains how anchoring the changes you want to make in your identity and physical environment allows you to make desired changes quickly and ones that stick. Whether your goal is better fitness and physical health, productivity or mental health, you'll learn actionable, zero-cost protocols to build powerful and meaningful habits. Sponsors AG1: https://drinkag1.com/huberman Lingo: https://hellolingo.com/huberman Wealthfront*: https://wealthfront.com/huberman Joovv: https://joovv.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 James Clear 00:02:57 Common Habits, Tool: Habit Success & Getting Started 00:06:16 Make Starting a Habit Easier, Tool: 4 Laws of Behavior Change 00:10:18 Sponsors: Lingo & Wealthfront 00:13:26 Writing Habits, Seasons & Flexibility; Adaptability, Tool: Bad Day Plan 00:18:42 Consistency, Flow vs Grind, Master Showing Up, Learning & Practice 00:24:54 Chunking, Getting Started at Gym 00:28:01 Flow Don't Fight, Dissatisfaction & Effort, Tool: Identity-Based Habits 00:34:10 Friction, Competition & Effort; Credentials 00:39:38 Make Effort Rewarding, Mindset, Tools: Previsualization, Emphasize Positives 00:45:59 Sponsors: AG1 & Joovv 00:48:56 Reflection & Learning, Tool: Self-Testing; Perfectionism, Tool: Curiosity 00:55:18 Striving vs Relaxation, Balance, Tool: Turn On/Off; Hiking, Nature Reset 01:04:20 Identity & Professional Pursuits; Choosing New Projects; Clinging to Identity 01:14:24 Sponsor: Eight Sleep 01:15:42 Criticism; Identity & Growth 01:21:47 Failure, Identity, Sports, Tool: Rebounding & Reaching; Public Failures 01:30:03 Daily Habits, Tools: Day in Quarters; Never Miss Twice; Meal Timing 01:38:22 Daily Habit Timing & Sequencing, Tool: Mindfully Choose Inputs 01:45:37 Creativity, Specialization vs Generalization; Books 01:51:31 Sponsor: Function 01:53:18 Habits & Context, Environmental Cues, Tools for Minimizing Phone Use 02:02:01 Bad Habits, Checking Phone, Tools for Breaking Bad Habits 02:08:21 Physical & Social Environment, New Habits, Tool: Join/Create Groups 02:18:40 Family, Habits; Kids & Parenting, Tools: Stimulus; Good Conditions 02:26:05 Impact of Habits, Habits as Solutions; Upcoming Projects 02:32:45 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter *This experience may not be representative of other Wealthfront clients, and there is no guarantee of future performance or success. Experiences will vary. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC, member FINRA/SIPC. Wealthfront Brokerage is not a bank. The base APY is 3.50% on cash deposits as of November 07, 2025, is representative, subject to change, and requires no minimum. If eligible for the overall boosted rate of 4.15% offered in connection with this promo, your boosted rate is also subject to change if the base rate decreases during the 3 month promo period. Funds in the Cash Account are swept to program banks, where it earns the variable APY. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Investment advisory services are provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value. Learn more about your ad choices. Visit megaphone.fm/adchoices
In today's episode, the discussion features Joanna M. Rhodes, MD, MSCE, director of Lymphoma and systems head for Lymphoma at Rutgers Cancer Institute of New Jersey and RWJBarnabas Health, alongside Krish Patel, MD, director of Lymphoma Research and executive chair of the Lymphoma Research Executive Committee at the Sarah Cannon Research Institute. Together, they discussed how the chronic lymphocytic leukemia (CLL) treatment paradigm continues to evolve with advances in targeted therapy. In this exclusive interview, Drs Rhodes and Patel highlighted key disease- and patient-related factors that guide first-line treatment selection, considerations that influence sequencing decisions in later lines of therapy, and how hematologists determine the optimal timing to transition between treatments. They also discussed the clinical distinctions between covalent and noncovalent BTK inhibitors, the current role of pirtobrutinib (Jaypirca) in CLL management, and how its safety profile and emerging data may inform future use earlier in the treatment course. The conversation concluded with reflections on the CLL data presented at the 2025 ASH Annual Meeting that were most relevant to clinical practice. nd many of your other favorite podcast platforms,* so you get a notification every time a new episode is posted. While you are there, please take a moment to rate us!
Drs. Herzberg and Yu continue their discussion on emerging clinical data presented at ESMO and WCLC 2025. They highlight recent advancements in HER2-targeted therapies for NSCLC and review new HER2-targeted therapies, international study results, and the promise of evolving targeted approaches for HER2-altered lung cancer.
Joshua Berman, MD, PhD, discusses how careful evaluation, patient priorities, and risk-benefit tradeoffs guide the use of interventional treatments when conventional approaches fall short. Dr. Berman also explains how tools such as ketamine, TMS, ECT, and neurofeedback can be used strategically—sometimes in sequence or combination—to address different vulnerabilities within mood-related brain circuits.Dr. Berman is Associate Professor of Psychiatry and Director of Interventional Psychiatry at NYU Langone Health.TopicsEvaluating patients who have not improved with medications or psychotherapyThe limitations of existing treatment guidelines for complex casesWhen and why sequencing or combining interventions may be appropriateEmerging approaches such as EEG-guided neurofeedback and focused ultrasoundBuilding a comprehensive, patient-centered interventional psychiatry programThis episode offers a clinician-level perspective on how interventional psychiatry is practiced today, and how new technologies may expand options for patients with the most challenging presentations.Chapters00:00 Introduction: Caring for Patients Who Don't Respond to Standard Treatment00:47 What Is Interventional Psychiatry?02:33 Evaluating Treatment-Resistant Presentations06:31 Precision, Patient Priorities, and Clinical Judgment09:35 Sequencing and Combining Interventions10:40 Limits of Treatment Guidelines12:18 The Future of Interventional Psychiatry13:23 Emerging Technologies: Neurofeedback and Focused Ultrasound17:15 Building a Comprehensive Interventional Program18:13 Tools vs. Understanding Brain CircuitsWatch Insights on Psychiatry on YouTubeExecutive Producer: Jon Earle
April co-founder and CEO Ben Borodach joins Fund/Build/Scale to break down how he built a compound startup in one of the hardest markets in fintech: U.S. taxes. We talk about why some problems can't be solved with a simple wedge product, how to sequence engineering, compliance, and distribution, and what it takes to operate inside complexity for years before the market catches up. Ben shares the early customer discovery work, the “science experiments” that shaped April's product, and the cultural frameworks he and his co-founder developed before they wrote any code. If you're an early-stage founder deciding what to build — or how to build it — this episode offers a clear playbook for choosing hard problems and de-risking them the right way. RUNTIME 48:00 EPISODE BREAKDOWN 01:08 How Ben and Daniel met + connecting over complex data problems 01:47 Ben's background: Deloitte, crypto infra, cyber, fintech 02:51 Why pick tax? Choosing a hard, high-impact market 03:44 Outdated incumbents + the opportunity hidden in “don't touch that” markets 04:57 Why tax innovation is so rare: regulatory hurdles and decades-old engines 05:29 Founder-market fit: complementary backgrounds + AI expertise 06:38 Translating congressional law into code + achieving 20× engineering leverage 07:25 The pseudo-manifesto: conflict resolution, culture, and founder alignment 08:40 What “compound startup” means and why narrow wedges don't work in B2B 09:57 Stitching data, workflows, and software into a flexible platform 10:39 Building for multiple configurations across financial institutions 11:26 How complexity becomes a moat 13:01 Why compound startups require longer gestation and patience 14:46 Sequencing layers: engine → coverage → interfaces → embedded infra 15:50 The rigid annual regulatory calendar and “Manhattan-style” planning 17:13 Serving customers early: friction with the market by design 18:46 Manual work vs. automation: the constant balancing act 19:27 The early KPI wasn't revenue it was proving technical and trust viability 20:46 Running “science experiments” to de-risk assumptions 21:16 Investor expectations vs. seasonal learning cycles 22:47 Surviving four years of annual gauntlets before scale 23:02 Inside the regulatory maze: IRS approval, state forms, arbitrary specs 24:04 Data governance challenges: CCPA, IRS 7216, portability 25:20 Why April participates in the industry's private governance body 26:18 Why April chose embedded distribution over a consumer app 27:32 The crumbling moats of financial institutions 29:08 Tax as the missing data layer enabling personalization 30:47 How customer discovery differed across banking, wealth, and SMB 31:07 Thousands of conversations across dozens of institutions 32:51 What April had to prove at Seed, Series A, Series B 33:49 Why rigid VC benchmarks can be unhelpful for complex companies 37:02 Headcount growth: seed → A → B 38:20 Why Ben doesn't interview every employee anymore 39:48 Founder evolution: doing → delegating → maintaining quality 40:55 Resilience, wellbeing, and founder longevity 41:39 The mythology of 996 and why it's unsustainable 44:07 The most common mistakes first-time fintech founders make 46:14 The one question Ben would ask if he were interviewing a founder LINKS Ben Borodach April Daniel Marcous april Raises $38M Series B to Embed Tax into Every Financial Decision April Careers SUBSCRIBE
Featuring perspectives from Dr Lisa A Carey and Dr Rita Nanda, including the following topics: Overview: Molecular basis of antibody-drug conjugate (ADC) toxicities — Sequencing of ADCs and mechanisms of resistance (0:00) Case: A woman in her late 60s with localized triple-negative breast cancer develops myocarditis during neoadjuvant therapy with chemotherapy/pembrolizumab — Richard Zelkowitz, MD (8:22) Case: A woman in her mid 70s with recurrent ER-negative, HER2-low, PD-L1-positive metastatic breast cancer (mBC) who experiences disease progression on nab paclitaxel/atezolizumab responds to sacituzumab govitecan — Ranju Gupta, MD (26:43) Case: A woman in her early 80s with recurrent ER-positive, HER2-low (IHC 1+) mBC experiences disease progression on trastuzumab deruxtecan (T-DXd), then receives datopotamab deruxtecan and develops pulmonary symptoms — Laila Agrawal, MD (32:11) Data Review: T-DXd (37:51) Case: A woman in her early 70s with recurrent ER-positive, HER2-low (IHC 1+) mBC, including bladder metastases, experiences disease progression after palbociclib/letrozole, then capivasertib/fulvestrant, then nab paclitaxel — Justin Favaro, MD, PhD (44:02) Case: A woman in her late 70s with ER-positive, HER2-low mBC who experiences disease progression after 1 year of ribociclib/letrozole receives sacituzumab govitecan — Erik Rupard, MD (55:19) CME information and select publications
Send us a textDr. Pankaj Agrawal, Division Chief of Neonatology at University of Miami, discusses rapid genomic advances—from six-month diagnostic timelines in 2000 to same-day sequencing today. While current practice targets phenotype-based testing for unexplained conditions or dysmorphic features, Agrawal advocates moving toward universal NICU sequencing to identify previously unrecognized conditions. Key barriers include administrative buy-in, cost concerns, consent processes, and result disclosure challenges. Even negative results provide value—offering families reassurance and contributing to research databases. With only 5,000 of 20,000 genes linked to human disease, ongoing gene discovery work continues. Agrawal emphasizes the NICU as ideal for genomic implementation given high genetic disease prevalence and intervention opportunities. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
Featuring an interview with Dr Matthew Lunning, including the following topics: Reflection on the advances made in chimeric antigen receptor (CAR) T-cell therapy (0:00) Overview of the CAR T-cell therapy administration process (4:40) Opportunities for referral for CAR T-cell therapy (10:05) Selection of a CAR T-cell therapy based on patient characteristics (16:09) Sequencing of CAR T-cell therapy for various non-Hodgkin lymphomas (23:23) Safety regulations and mitigation strategies for adverse events (30:36) Case: A woman in her early 80s with relapsed/refractory (R/R) diffuse large B-cell lymphoma receives lisocabtagene maraleucel (36:16) Case: A man in his early 60s with R/R mantle cell lymphoma receives brexucabtagene autoleucel (43:09) Case: A man in his early 60s with R/R multiple myeloma receives ciltacabtagene autoleucel (49:09) CME information and select publications
As a property management business owner, you likely work with seasoned investors who are always looking for new ways to build and preserve their wealth and assets. In this episode of the #DoorGrowShow, property management growth expert Jason Hull sits down with Alan Porter to discuss how to reveal the powerful financial strategies the wealthy and large financial institutions use and how you can apply them. You'll Learn [01:09] Alan's Inspiration for Uncovering Financial Secrets [08:38] Learning Financial Planning Strategies 90% of People Don't Know [12:25] How to Get Started on the Path to Tax-Free Retirement [15:43] Strategies For Property Managers and Their Clients Quotables "The one thing you can always trust is for everybody to look out for their own self-interest." "If your own self-interest is in alignment with their interests, then that's a win-win. Otherwise, someone's gonna lose." "If you don't have a plan, make one. But you've got to have a plan and improve on it all the time." Resources DoorGrow and Scale Mastermind DoorGrow Academy DoorGrow on YouTube DoorGrowClub DoorGrowLive Transcript Alan Porter (00:00) I teach people to think outside the box, conventional financial planning, and show them the strategies that the wealthy and banking institutions have been using for years. Now, I show people how to become their own bank. Jason Hull (00:10) All right, welcome everybody. I am Jason Hull, the founder and CEO of DoorGrow, the world's leading and most comprehensive coaching and consulting firm for long-term residential property management entrepreneurs. For over a decade and a half, we have brought innovative strategies and optimization to the property management industry. We have spoken to thousands of property management business owners, coached, consulted, cleaned up hundreds of businesses. Alan Porter (00:26) Thank Jason Hull (00:35) helping them add doors, improve pricing, increase profit, simplify operations. And we run the leading property management mastermind in the industry. At DoorGrow, we believe good property managers can change the world and that property management is the ultimate high trust gateway to real estate deals, relationships, and residual income. We are on a mission to transform property management business owners and their businesses. We want to transform the industry. eliminate the BS, build awareness, change perception, expand the market, and help the best property management entrepreneurs win. Now, let's get into the show. So my guest today is Alan Porter of Strategic Wealth Strategies. Welcome, Alan. Alan Porter (01:16) Well, thank you for having me on. Jason Hull (01:18) Yeah, glad to have you. And we're going to be talking about, he's going to be sharing how to reveal the powerful financial strategies, the wealthy use, how you can apply them to. Alan will be uncovering the IRS approved playbook for retiring completely tax free, explain the millionaire tax strategies business owners use to keep more of what they earn and break down Wall Street myths to show how to build lasting wealth without market volatility. So Alan. Again, welcome to the show and why don't we kick things off by give us a little bit of background on you. How did you get into entrepreneurism, into business and give us a little bit of backstory so we understand how this all came to be. Alan Porter (02:00) Well, I never thought I'd be doing this. I retired from the military back in 1993. I was a Blackhawk instructor pilot and I told everybody I had a safe landing for every takeoff and I dodged all the bullets and I had a great career. And I got enrolled in the real estate mortgage business after that up till about 2008. I've had some tragic things happen to my family. In 2009, live in Little, mean Fayetteville, North Carolina. My son lived in Little Rock, Arkansas with his wife, Lynn. She was 39 and they had two little girls that were seven and four. Jason Hull (02:19) in 2009. Alan Porter (02:28) Well, we went down there for Christmas in 2009, but my son had been 100 % disabled for three years and still not getting the disability. And January 5th changed my entire life. His wife, Lynn, called me up. said, Alan, I've been diagnosed with stage four pancreatic cancer and they've given me six months to live. Of course we were all devastated, but there's a huge financial problem that's developed in my son's family because there's no money coming in. Jason Hull (02:28) Well, we went down there for business in 2009, but my son had been 100 % disabled for three years and still not in a disability. Wow. And January 5th changed my entire life. His wife Lynn called me up, she said, Alan, I've been diagnosed with stage 4 pancreatic cancer and they've given me six months to live. Of course, we were all devastated. Yeah, I bet. there's huge financial problem that's developed in my son's family because of the money coming in. Alan Porter (02:55) I'm helping them out, but I don't know for how long Jason Hull (02:55) I'm helping him out, but I don't help him. Alan Porter (02:56) until I'm gonna have to sell my house or do something. But I was like 99 % of the people out there, Jason, that thought life insurance was a death product that you had to die to benefit from it. Well, little did I know she had a terminal illness right or her life insurance policy that she could access within one year of diagnosis of this deadly disease and was completely tax free, which I knew nothing about. It was hundreds of thousands of dollars. Jason Hull (02:58) Yeah. Really? Alan Porter (03:21) And if it had not been for that, my son would be bankrupt and it took a huge financial strain off of me. Jason Hull (03:25) Yeah. Well, long story short, died a year later, so I moved my son back here to Fayetteville, North Carolina. But about a year after that, my daughter's an oncology nurse, and her husband's a doctor at Woodbrook and Raleigh, North Carolina, and just gave birth to my third grandson. And she was diagnosed with breast cancer, and it was very bad. We didn't think she was going to live. Well, now in 2023, she's been 12 years cancer free, but she also was diagnosed with Graves' disease, thyroid eye condition. Alan Porter (03:26) Well, to a long story short, she died a year later. So I moved my son back here to Fayetteville, North Carolina. But about a year after that, my daughter, who's an oncology nurse and her husband's a doctor, they live up in Raleigh, North Carolina, had just given birth to my third grandson. And she was diagnosed with breast cancer and it was very bad. We didn't think she was going to live. Well, now in 2023, she'd been 12 years cancer free, but she also was diagnosed with Graves disease and thyroid eye condition. There's only one treatment for it. It's not a cure-all for anything, but Jason Hull (03:51) And there's only one treatment for it. It's not a cure-all. Alan Porter (03:55) it's a treatment. It's an infusion, eight infusions of this drug is called Tepezza I believe. The first one was like $32,000. The last one was almost a quarter of a million dollars. That was in May of 2023. On January of 2024, the thyroid eye condition came back. In February, she went to the doctor. The doctor said, Nicole, I'm sorry, there's nothing we can do until you go blind and then we can operate. I'm thinking, man, what a prognosis. Jason Hull (03:55) my Yeah. ⁓ Alan Porter (04:21) So we tried to get her a study at Duke. She didn't qualify for that because she had already taken the Tepezza But April did get her into the Mayo Clinic in Rochester, Minnesota. But basically there's nothing they can do for her. She was up there for about four days for testing and consultation. But basically, like I said, there's nothing they can do for her. They got a drug that may be 50 % effective. It's not improved by insurance. And believe it or not, it's even more expensive than the Tepezza is. And it's just, I mean, so. Jason Hull (04:39) Yeah. Yeah. Alan Porter (04:51) So both of my kids are living day to day in misery. And when I got started in this, knew, like I said, these things, because I was to have a very successful real estate mortgage business. And I said, these financial strategies that the insurance companies have, why don't people know about this? These are the greatest financial vehicles out there. People tell me, well, listen to Suzy Orman and Dave Ramsey, insurance is not a good investment. Well, first off, it's not an investment. Jason Hull (04:54) When I got started in this, knew, like I said, these things, because I was very successful in estate in my early years. I said, these financial strategies that the insurance companies have, why don't people know about this? These are the greatest financial vehicles out there. People tell me, listen, as soon as you arm it today, Ramsey, insurance is not a good investment. Well, first off, it's not an investment. Alan Porter (05:18) It's an asset class all of its own. There's no other financial product that can Jason Hull (05:19) It's an asset class all of itself. There's no other financial product that... Alan Porter (05:23) provide the protection, performance, and benefits of cash value life insurance when properly structured and fixed and fixed indexed annually. And I'll give you one big point. They eliminate or mitigate the risk in retirement that a stock portfolio only compounds. That's absolutely... Let me ask you this. Have you ever heard of sequence of returns risk? Jason Hull (05:23) could provide the protection, performance, and benefits of cash, money, or life insurance. Yeah. if you have one big point, they eliminate or mitigate the risk in retirement that a stock portfolio only compacts. That's absolutely, let me ask you this, have you ever heard of sequence of returns risk? Sequencing returns? Sequence of returns risk. No. Alan Porter (05:46) Sequence of returns risk. Well, don't feel lonely because 99 % of the people I talk to, to include multi-millionaires that have fee-based advisors. And let's say that you're 65 years of age and you go to retire and you got a million dollars in your stock portfolio. They used to say a 4 % distribution rate was a safe distribution rate to last for 30 years, index for inflation at 3%. Well, my plans go to age 120. They don't cut off in 30 years. Jason Hull (05:50) Well, don't feel lonely because 99 % of the people I talk to include multi-millionaires that have fee-based advisors. let's say that you're 65 years of age and you go to retire. You have a million dollars in your stock portfolio. They used to say a 4 % distribution rate was a safe distribution rate to last for 30 years, index for inflation at 3%. Well, my plans go at age 120. They don't cut off in 30 years. But the problem with that 4 % distribution rate Alan Porter (06:15) But the problem is that 4 % distribution rate, that's Jason Hull (06:19) That's $40,000 a year. And that stock portfolio, that's not guaranteed. What if you have a 10 % loss the first year? now your million dollars goes down to $900,000 minus the $40,000 you took out minus the fees you paid on financial advisor whether you make money or not. And then the next two to three years, 2008 happens again, where you lost 38 to 52%. You never got the money in the fifth year. And when I tell people about this, they're financial advisors, Alan Porter (06:19) $40,000 a year. And that stock portfolio, that's not guaranteed. What if you have a 10 % loss the first year? So now your million dollars goes down to 900,000 minus the $40,000 you took out minus the fees you pay that financial advisor, whether you make money or not. And then the next two to three years, 2008 happens again, where you lost 38 to 52%. You're going to be out of money in the fifth year. And when I tell people about this and their financial advisors, Don't tell them, I mean, they're said, I said, why do you think that is? Jason Hull (06:45) don't tell them. I made letters, I said, why do you think that is? Alan Porter (06:48) It's because they make a fee whether you make money or not. The number one fear in retirement is running out of money before you run out of money. I can eliminate that. Jason Hull (06:49) Because they make a fee, well, if you make money or not. The number one fair return is 20,000 dollars. Yeah, compensation structures are incentive models. And so if their incentive is not to tell you, it's because they're getting paid to not tell you. Well, they're supposed to be fiduciary looking out for their best interest clients. I'm a certified financial financial advisor. Yeah, but regardless, the one thing you can always trust is for everybody to look out for their own self-interest. Oh, you're right there. Alan Porter (06:59) Yeah, exactly right. Well, they're supposed to be fiduciaries looking out for their best interest clients. I'm a certified financial fiduciary. you're right there. Jason Hull (07:18) So if your own self-interest is in alignment with their interests, then that's a win-win. Otherwise, someone's gonna lose. Yeah. It's always the clients. Yeah. Yeah. Okay, well, that's quite the story. how is everybody doing now? Alan Porter (07:26) Yep. And it's always the client. My son looks like he's 85 years old and my daughter's living day to day in pain. Jason Hull (07:43) Yeah, yeah. So you have this burden of trying to figure out how do I take care of them? How do I make sure that, you know, taking care of your kids and, you know, nothing's more stressful emotionally or more motivating for us as a parent than our own kids having it going through a tough time. Yeah. I remember my oldest daughter, she was born with a birth defect that there was a rotation in her gut and she was just always sick, throwing up, stuff like this. Well, she almost died. We didn't know this. got, went and got a scan. Everything was inflamed. They're like, we have to do emergency surgery immediately. And yeah, it was pretty scary as a parent. And they had to like pull her guts out, do surgery, put them back in. And she was a little kid, you know? Now she's my oldest. I mean, she's still my oldest, but now she works for me. and in DoorGrow which is great. But yeah, I remember those times. That's really scary. And I can imagine that's just really a big load on your shoulders. So did this kind of spark you creating the strategic wealth strategies then? Alan Porter (08:30) No. Absolutely, that's my passion for this. I'm very passionate about what I do. It's all about education because people don't know. Jason Hull (08:49) Explain the passion, like what gets you excited about this? Alan Porter (08:53) Well, educating people. That's what I did in the Army. I was an educator. I taught people how to fly. it's just like this, educating people. I teach people to think outside the box, conventional financial planning, and show them the strategies that the wealthy and banking institutions have been using for years. Now, I show people how to become their own bank. I've been doing this for a decade and a half. And why don't everybody doesn't do this? I don't know why. mean, you borrow money from yourself, you pay yourself back compound interest. Jason Hull (09:16) you Alan Porter (09:20) and not the financial institutions and you eliminate the effective interest cost that you pay on the money that you borrow. And people, are you aware of what effective interest cost is? Banks love it. I had a gentleman who wanted to do my debt free for life plan. And I said, well, how much debt do you have? He says, well, we bought a new house a couple of months ago, a couple of car payments, a loan and a credit card. I said, what's the interest rate on your mortgage? He said 2.75. Jason Hull (09:20) Yeah. And people, are you aware? No, what is that? Alan Porter (09:46) I said, what's your effective interest cost on that? He says, well, I don't know what you're talking about, Alan. I said, don't fill it, only most people don't. Fill out my form, we'll do a Zoom conference the following week. I said, you got $461,000 in debt. That's not your problem. The problem is the 49.76 effective interest cost, you're paying on that 2.75 % mortgage. His eyes got real big and he said, Alan, how is that possible? I said, it's not going to get down to the 2.75 until the last couple of months of the mortgage. Jason Hull (10:10) Yeah. ⁓ Alan Porter (10:14) You've got a credit card here that's over 90 % effective interest cost. And even though you've got great credits, your average effective interest cost is over 46%. So my next question to him was, what financial vehicle are you investing in, your 401k or anything else, that gives you a 46 % return on your money? Because 46 cents of every dollar that you pay out goes to compound interest for some financial institution, and that money's gone for you forever. Jason Hull (10:17) and ⁓ Alan Porter (10:38) He said, well, nothing. In fact, I lost 10 % of my 401k. Jason Hull (10:40) Yeah, that'd be hard to find that much. And then my last question was how long does it you to your debts off? I said with my cap three buck of money and a whole lot of insurance policy, 14.17 years past, saving $73,000. And in the 10th year it would be 52 years of bids, and there's over $149,000 in cap Alan Porter (10:43) And then my last question was, how long can it take you to pay your debts off the way you're doing it? I 20 some years. I said, with my tax-free bucket of money and a whole life insurance policy and our software, we're paying all your debts off 14.17 years faster, saving you $73,000 in interest. And in the 10th year, you'll be 52 years of age and there's over $139,000 in a tax-free bucket of money that you can use ⁓ to buy a new car, whatever, college education for your kids. Jason Hull (11:06) you can use uh buy a new car whatever college education for your kids at that point your debt benefits will be $400,000 in tax-free money from the federal bank but think about this you don't have to any more money in this by the time you're 65 there'll be over $400,000 in tax-free money that you can use to supplement your income that does not affect the taxation of social security or the tax and community care part which will be in the thousands per year Alan Porter (11:13) At that point, your debt benefits over $400,000 of tax-free money to protect your family. Think about this. You don't have to put any more money in this. By the time you're 65, there'll be over a quarter of a million dollars in a tax-free bucket of money that you can use to supplement your income that does not affect the taxation of Social Security or the means testing for Medicare Part B, which will be in the thousands per year. You're protected from lawsuits, liens, and judgments, and it eliminates or mitigates all the risk in retirement. This is absolutely great for real estate investors. Jason Hull (11:35) Yeah. Yeah ⁓ Alan Porter (11:42) Because once they build that money up in the cash value of their policy, they can take it, go buy a property, and pay themselves back. I do this all the time. I just bought two new cars in last two years. I pay myself back. I'm going to have tens of thousands of dollars more because I compounded interest for me instead of some financial institution. Jason Hull (12:03) So you said multiple times, like why aren't people doing this? Well maybe you could answer your own question, why aren't people doing this? Alan Porter (12:10) It's lack of education. It ought to be taught in high school, but it's not. I've got college professors with PhD degrees in accounting and finance. They have no idea what I'm talking about. They ask me to teach their classes. Jason Hull (12:20) Yeah, got it. So it was just a lack of education on this. Alan Porter (12:24) That's exactly what it is. Jason Hull (12:25) So, yeah, well, I mean, it sounds like something that everybody should be doing. So how does somebody get started with this or how do they become aware of this or what would you say are the first steps? Alan Porter (12:38) Well, give me a call. I don't charge for my consultation services. That's free. It's an education. I think everybody needs to know these things because it will change their financial future, not only for them, but for their family also and possibly generations to come. at 9-8-5. Jason Hull (12:52) So Alan, it sounds like you've kind of found a passion in this. You really enjoy helping people to be able to figure this out and do this. Alan Porter (13:00) Absolutely. Jason Hull (13:01) So yeah, I think that's noble. I think this is pretty awesome. So for those that are listening to this point, I'm going to read a quick word from our sponsor and then Alan, I'm going have you share your phone number so they can get in touch with you and we can keep talking about it. So this episode is sponsored by KRS Smart Books. So if you're a property manager, are you tired of getting tangled up in numbers? KRS Smart Books has your back. They specialize in property bookkeeping. for small to mid-sized managers who'd rather focus on, well, managing. With over 15 years of experience in real estate accounting, their pros in AppFolio, Yardi, and all the top property management software, trust them to make your monthly reports hassle-free so you can get back to what really matters running your business. Head over to krsbooks.com to book your free discovery call. All right, so Alan, what's the number that they should get? to get in touch with you or to reach you to find out about this. Alan Porter (13:59) You can call me at 910-551-1046, email me at strategicwealth, the number zero at gmail.com. And you can always go to my website, which is www.strategicwealthstrategies.com and you can book appointment there. And I've got a plethora of information on that website. Jason Hull (14:18) What? Great, thanks for sharing. So for those that are listening, some people might listen to this and go, well, that's nice, but Alan probably can only work with people that maybe have a million dollars or that are ultra wealthy or have lots of savings. People will listen to this and say, that's probably not for me. What would you say to that? Alan Porter (14:39) Well, quite frankly, bull I work with everybody. know, I'm for the military. Military people don't make a lot of money. Okay. And I work with them, but I work with regular, regular working people that I mean, I'll give you a perfect example. I asked people, said, why do you contribute to a 401k? They said, well, it's a tax deduction. I said, no, it's a tax compounder. And I thought you don't think tax is going to be higher when you retire. I got another thing coming for you. Jason Hull (14:43) Okay. Right. Alan Porter (15:07) But see, thing is people don't understand. 1 % of people out there don't even think there's a fee in a 401k. A 1 % fee over a 30-year period will reduce your income by one-third. The average fee in a 401k is 2.99%. Now that's by Forbes Magazine and the Laptimes. People have less than two-thirds of their money and then they get hit with taxes anywhere from 20 to over 55%. And they're not prepared for it. They're not prepared for long-term care, which costs right now between $50,000 to $200,000 a year. I can get money for that's tax free for pennies on the dollar. It's just a matter of education. Jason Hull (15:43) So for the property management business owners listening, a lot of them will have sometimes hundreds of clients that are investors and they're wanting to maximize their investments, how would this maybe benefit the property management business owners to be better educated on this and have a strategic partner like you? Alan Porter (16:03) Well, the thing is, you've to have a plan. If you don't have a plan, make one. But you've got to have a plan and improve on it all the time. But it's just like, you know, building up your cash value and borrowing from yourself to buy a property and paying yourself back. That's an absolutely great thing for a real estate investor. And these property managers, I've got health and wellness programs. If you've got employees over 10 employees, understand this. The employer will save anywhere from $500 to $700 a year in FICA taxes. The employee and the employer have 1,100 drugs, prescription drugs, at zero copay. That's 20 to 30 % of healthcare costs. Jason Hull (16:37) Yeah Alan Porter (16:50) I mean, and they also have an accidental indemnity program and that's not for the employer, but they have a revolution health app. They've got the number one telehealth app according to JD Power and associates. It's a plethora of benefits. We have legal club, we have identity shield. It's just all at no net cost to employer and no net cost to the employee. It's the section 125 of the tax program. Jason Hull (17:06) This is all at no net cost reported at no net cost reported. Got it. Got it, interesting. Okay, well cool. Well what else would people generally ask about this or should we make sure that the listeners are aware of related to this? Well, are you... Alan Porter (17:26) Well, are you risk averse? Are you conservative? You know, it's just like when you go to retire and you've got that million dollars in stock portfolio, a 4 % distribution rate, $40,000. If you had a property constructed fixed indexed annuity at, say, age 65, you'd only need approximately $650,000 of that stock portfolio to give you the same $40,000 a year. That's guaranteed for the rest of your life. we're guaranteed. Jason Hull (17:53) New York Heat. ⁓ Alan Porter (17:53) Never to have a loss through the market because we're not tied to the market for our gain. We use indexing strategies and every time that indexing strategy goes up we have increasing income and the older you get the higher the distribution rate is. You can't do that with a stock portfolio. It's not even comparable. Jason Hull (17:59) And every time that index of strategy goes up, we have increasing income. And the older you get, the Yeah, yeah. Well, Alan, I appreciate you coming on to the DoorGrow show and bringing this to light for those listening that are not aware you're doing your purpose of educating. So appreciate that. And to wrap up what final words do you have? And then again, why don't you go and share how people can get in touch with you one more time. Alan Porter (18:31) Okay, well I've got a best-selling book out right now on Amazon. It's called Tax-Free Retirement Solution. Again, Tax-Free, Tax-Free Retirement Solution. Jason Hull (18:38) It's called tax, tax free. Retirement solution, okay. Got it. Alan Porter (18:45) And again, you can call me at 910-551-1046. My email is strategicwealth, the number zero at gmail.com. And you can go to my website, which has a plethora. I've got videos, I've got blogs, I've got everything there. And you can book an appointment there at www.strategicwealthstrategies.com. Jason Hull (18:51) email is strategicwealth0 at gmail.com and you can go to my website which has a cluster. I've got videos, I've got blogs. book an appointment there at www.strategicwellscladagy.com. Awesome. Alan, appreciate you being on the show and thanks for your service. You mentioned your former military. Yeah, I appreciate it. So for those watching, if you've ever felt stuck or stagnant in your property management business, you want to take it to the next level, reach out to us at doorgrow.com. Also be sure to join our free Facebook community, Just for Property Management Business Owners at doorgrowclub.com. Alan Porter (19:13) Well, I appreciate it. Jason Hull (19:31) And if you would like to get the best ideas in property management, join our free newsletter at doorgrow.com slash subscribe. And if you found this even a little bit helpful, don't forget to subscribe and leave us a review. We'd really appreciate it. And until next time, remember the slowest path to growth is to do it alone. So let's grow together. Bye everyone.
Ryan Fahey (pronounced “Foy”) — consultant, speaker, and author of four books helping educators launch and scale as entrepreneurs.Big ideas & highlightsAuthentic > algorithmic: why clear opinions outperform beige, AI-generated content.The “last 20%” of growth: being fully yourself so the right people follow.Teachers → founders: turning buried skills into offers, pricing with confidence.Speaking starter kit: assets to collect before chasing stages.“Add value daily”: the habit that compounds in life and business.Impact beyond the balance sheet—and why sticking around wins the long gameTimestamps / chapters00:00 – Cold open, baseball talk, PEI & Blue Ridge vibes03:55 – Who is Ryan Fahey? Dad, husband, entrepreneur, speaker, author05:40 – Authenticity as the growth unlock (“the last 20%”)07:50 – AI everywhere vs. human voice; why 1 real video beats 100 clones09:25 – “Don't be the mayor of vanilla town”: have an opinion, repel & attract11:45 – Niche & offers: helping educators become entrepreneurs14:45 – Humble pricing, buried skills, and making the leap efficiently16:50 – Should you write the book first? Sequencing brand → book for lift17:55 – Speaking: assets, testimonials, and building your page18:40 – First stage stories and the virtual keynote era21:33 – Listener chain: “What keystone habits make you unstoppable?”22:15 – Impact goals that don't show up on a P&L23:53 – Rodric on service, time studies, and keeping energy-rich workRyan Fahey Quotes:“Don't be the mayor of vanilla town.”“People follow real people. One piece of you beats 100 pieces of fake you.”“If you add value daily, the market will reward you over time.”“Most teachers already have the skills— they're just buried.”“Stick around long enough and you win the long game.”Resources & mentionsRyan's site: faheyconsulting.orgLinkedIn: https://www.linkedin.com/company/fahey-consulting/Instagram: https://www.instagram.com/wellnessrf88/Facebook: https://www.facebook.com/wellnessrfRodric's foundation: Send a Student Leader Abroad (SASLA)EF Tours (context around student travel)Books referenced: Robin SharmaHousekeepingRyan's question for the next guest: “What keystone habits make you unstoppable?”Pronunciation note: Fahey = “Foy.”Resources:Million Dollar Flip FlopsFollow Us on Insta Ready to transform your business and your life while making a difference? Grab your copy of *Million Dollar Flip Flops*—the ultimate guide to creating a life and business that feels just as good as it looks. And here's the best part: 100% of the proceeds go directly to our foundation, Send a Student Leader Abroad, with a goal of sending 1,000,000...
Is the most important part of plastic surgery the scalpel—or the psychology behind why you choose it and how you feel afterward?In this candid episode of Plastic Surgery Uncensored, I sit down with my longtime patient-turned-friend, Alexis, to unpack her 15-year journey—four surgeries, eight procedures—and the mindset shifts behind each decision. From a post-pregnancy mommy makeover (tummy tuck with diastasis repair) to a breast lift with implants, then subtle upper-face rejuvenation (limited lateral brow lift + upper lids), and finally a lower-face/neck transformation (deep-plane facelift + small chin implant + lower lids + micro-fat grafting), we show how sequencing, restraint, and honesty can deliver results that look fresh—not “done.” We talk openly about why some patients stay secretive, why others are proudly transparent, and how to navigate judgment, social media distortion, and the myth that more procedures = a “cat face.” You'll also hear how motherhood, weight changes, and aging shift priorities—and why sometimes the kindest thing you can do for your family is to put your own “oxygen mask” on first.In this episode, you'll learn:The right procedure at the right time: why exercise can't fix loose skin or diastasis, and when surgery is the missing puzzle piece.Sequencing that makes sense: convenience, recovery, and why breasts + abdomen often play better together.Face vs. filler: when fillers help—and when a facelift/necklift is the “screwdriver,” not the hammer.Chin implant reality check: tiny, customized implants that sharpen a jawline without changing who you are.Natural, not noticeable: how subtle technique (and using less pull, not more) avoids the “weird” look.Mindset matters: dropping shame, embracing empowerment, and being honest for the sake of others' expectations.Who this episode is for: those considering a mommy makeover, anyone debating face/neck rejuvenation in their 40s–50s, and listeners confused by the internet's extremes who just want practical, compassionate guidance.If this helped you, pay it forward:Leave a kind review (it means the world to our team), and share the episode with anyone you love who's thinking about plastic surgery—before they book, so they can make informed choices. — Dr. Rady Rahban, Plastic Surgery Uncensored✨ If you enjoyed this episode of Plastic Surgery Uncensored:✔️ Subscribe on Apple Podcasts, Spotify, or wherever you listen.✔️ Rate & Review—your feedback helps more people find us.✔️ Follow Dr. Rady Rahban across all platforms for daily insights, behind-the-scenes, and patient education:Instagram: @drradyrahbanTikTok: @radyrahbanMDYouTube: @Rady RahbanFacebook: @Rady Rahban✔️ Share this episode with someone considering plastic surgery—the right knowledge can save a life.