In genetics and biochemistry, determining the structure of an unbranched biopolymer
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Grand Rapids, Michigan, October 15, 2025 ⎯ Today, Sequencing.com (Sequencing), a biotech company offering the world's largest platform for whole genome sequencing and personalized health insights, announces a partnership with true. Women's Health, a concierge medical practice providing personalized care to women of all ages. true. Women's Health focuses on midlife, menopause, sexual health, and weight management through a membership-based model. Now with Sequencing, their patients can gain insights into ~100% of their DNA test data and screen for almost all known health conditions, traits, and medication responses. Then, they can work with true. providers to translate that knowledge into clear, actionable steps for managing risks, optimizing wellness, and extending longevity. Whole genome sequencing offers women deeper insight into their risk for heart disease, cancer, and metabolic conditions. For the first time, true. Women's Health will integrate DNA insights directly into personalized care plans for women navigating perimenopause and menopause. true. patients can take a test with one of Sequencing's custom kit bundles, which requires a simple cheek swab, and within weeks, they will have their results. Dr. Celia Egan, MD, MSCP, DABOM, true. Women's Health Director of Obesity Medicine & Metabolic Health says, "Our vision is to offer a comprehensive framework for lifelong wellness through our programs. Many of our patients are interested in genetic tests but are rightfully nervous about choosing the appropriate one and understanding the results. As a clinician, I shared that challenge. I needed a genetics test that could fit directly into our programs, but struggled to find reports that aligned with our pillars for easier patient understanding. Sequencing is the perfect solution." Allyn Lebster, true. Women's Health President & Co-founder says, "Sequencing is working with us to provide a customized report bundle that maps directly to our wellness pillars, from metabolic health and cancer to bone density and emotional coping. This integration is the key. It finally allows us to guide patients in both test selection and result interpretation, turning complex genetic data into a clear, actionable part of their personalized health journey." Dr. Brandon Colby, MD, Sequencing Founder & CEO, says, "true. Women's Health patients only need to be sequenced once, and from that single, definitive dataset, our platform becomes a permanent health resource, evolving alongside new scientific discoveries, medical research, and personal health goals. We're honored to partner with true. to better serve women and to tailor our sequencing service to align with their wellness programs." This week, true. Women's Health hosted a public event for women to learn more about the new Sequencing partnership and to engage in whole genome sequencing themselves. Dr. Celia Egan shared how genomics fits into personalized healthcare, Sequencing walked patients through the science and the reports they will receive, and true. providers answered questions about how genetic testing can support midlife, menopause, and long-term health. Importantly, Sequencing offers the most private DNA test on the market with HIPAA and US-EU-UK-Swiss Data Privacy Framework compliance. Testing is also performed in CLIA-certified, CAP-accredited clinical sequencing laboratories in the United States. Learn more about this partnership at https://truewomenshealth.com/sequencing/. About Sequencing.com Founded by Dr. Brandon Colby, MD, Sequencing.com (Sequencing) is a U.S. biotech company offering whole genome sequencing that unlocks the most complete view of DNA. Most DNA tests allow users to gain insight into less than 0.1% of their DNA data, but Sequencing allows users to obtain ~100%. The company screens for almost all known health conditions, traits, and medication responses, then translates that knowledge into clear, actionable steps for managing risks, optimizing wellness, and extending longevity. The platform continuously reanalyzes information throughout a person's life, evolving alongside new scientific discoveries, medical research, and personal health goals. Sequencing offers the most private DNA test on the market with HIPAA and US-EU-UK-Swiss Data Privacy Framework compliance. Their whole genome sequencing is performed in CLIA-certified, CAP-accredited clinical sequencing laboratories in the U.S. To learn more about Sequencing, please visit Sequencing.com and LinkedIn. About true. Women's Health About True Women's Health (true.) true. Women's Health® is a Grand Rapids-based concierge medicine practice dedicated to women's health across all stages of life. Specializing in midlife, menopause, sexual health, lifestyle medicine, and weight management, true. delivers personalized care that emphasizes prevention, education, and patient goals. Founded by nationally recognized menopause expert Dr. Diana Bitner, MD, MSCP, FACOG, and healthcare executive and attorney Allyn Lebster, true. is transforming how women experience healthcare in Michigan and beyond. Learn more at truewomenshealth.com. Media Contact: Amanda Bell PR Lead amanda@sequencing.com SOURCE: https://sequencing.com/blog/post/sequencingcom-true-women%E2%80%99s-health-now-incorporates-whole-genome-sequencing-their-complete
In this episode, we dive deep into the world of yoga sequencing with expert Charlotte Muller, who shares her journey from discovering yoga as a grieving tool to becoming a master at crafting creative sequences using her method called foreshadowing. You'll learn about: The importance of creative sequencing, Incorporating foreshadowing into your system, And how these techniques can transform your teaching and student engagement. Charlotte also discusses the role of balance in class planning, the impact of personalized teaching, and how she grows a highly engaged clientele base in-person and online. Whether you're a seasoned instructor or a new teacher, this episode is packed with insights for how you teach creative yoga classes and how you operate your business as a yoga teacher. Meet Charlotte Muller: After the unexpected loss of her mom and the diagnosis of Familial Hypercholesterolemia (FH) at age 17, Charlotte dove into wellness as an attempt to care for her heart, physically and emotionally. Breathe Strength was born from her united love for yoga and fitness. Charlotte's been teaching since 2012. Her certifications include ERYT-500, YACEP, RYS, Yoga Teacher Trainer, Group Fitness Instructor, Personal Trainer, Blissflow Yoga, Trauma Informed Yoga, and AHA Heartsaver CPR Instructor. She also taught yoga theory + practice at Hofstra University as an adjunct professor. Charlotte is well known for her creative style sequencing, specifically using the element of foreshadowing, and runs a yoga teacher membership called the Sequencing Hub. She is passionate about helping other yoga teachers save time, teach creative classes, and continue their education, and loves creating community for yoga teachers + students alike. Episode Links: Check out our top resources for building your yoga business: https://allmatstaken.com/resources Connect with Adrianne on Instagram: https://www.instagram.com/allmatstaken/ (new podcast account) Watch on YouTube: https://youtu.be/B9WU3v14atU Follow Charlotte on Instagram: https://www.instagram.com/breathe_strength Visit Charlotte's Website: https://bio.site/breathe_strength Try Manychat: https://manychat.com/
Send us a textDr. Pankaj Agrawal, Division Chief of Neonatology at University of Miami, discusses rapid genomic advances—from six-month diagnostic timelines in 2000 to same-day sequencing today. While current practice targets phenotype-based testing for unexplained conditions or dysmorphic features, Agrawal advocates moving toward universal NICU sequencing to identify previously unrecognized conditions. Key barriers include administrative buy-in, cost concerns, consent processes, and result disclosure challenges. Even negative results provide value—offering families reassurance and contributing to research databases. With only 5,000 of 20,000 genes linked to human disease, ongoing gene discovery work continues. Agrawal emphasizes the NICU as ideal for genomic implementation given high genetic disease prevalence and intervention opportunities. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
Every few years, the world of product management goes through a phase shift. When I started at Microsoft in the early 2000s, we shipped Office in boxes. Product cycles were long, engineering was expensive, and user research moved at the speed of snail mail. Fast forward a decade and the cloud era reset the speed at which we build, measure, and learn. Then mobile reshaped everything we thought we knew about attention, engagement, and distribution.Now we are standing at the edge of another shift. Not a small shift, but a tectonic one. Artificial intelligence is rewriting the rules of product creation, product discovery, product expectations, and product careers.To help make sense of this moment, I hosted a panel of world class product leaders on the Fireside PM podcast:• Rami Abu-Zahra, Amazon product leader across Kindle, Books, and Prime Video• Todd Beaupre, Product Director at YouTube leading Home and Recommendations• Joe Corkery, CEO and cofounder of Jaide Health • Tom Leung (me), Partner at Palo Alto Foundry• Lauren Nagel, VP Product at Mezmo• David Nydegger, Chief Product Officer at OvivaThese are leaders running massive consumer platforms, high stakes health tech, and fast moving developer tools. The conversation was rich, honest, and filled with specific examples. This post summarizes the discussion, adds my own reflections, and offers a practical guide for early and mid career PMs who want to stay relevant in a world where AI is redefining what great product management looks like.Table of Contents* What AI Cannot Do and Why PM Judgment Still Matters* The New AI Literacy: What PMs Must Know by 2026* Why Building AI Products Speeds Up Some Cycles and Slows Down Others* Whether the PM, Eng, UX Trifecta Still Stands* The Biggest Risks AI Introduces Into Product Development* Actionable Advice for Early and Mid Career PMs* My Takeaways and What Really Matters Going Forward* Closing Thoughts and Coaching Practice1. What AI Cannot Do and Why PM Judgment Still MattersWe opened the panel with a foundational question. As AI becomes more capable every quarter, what is left for humans to do. Where do PMs still add irreplaceable value. It is the question every PM secretly wonders.Todd put it simply: “At the end of the day, you have to make some judgment calls. We are not going to turn that over anytime soon.”This theme came up again and again. AI is phenomenal at synthesizing, drafting, exploring, and narrowing. But it does not have conviction. It does not have lived experience. It does not feel user pain. It does not carry responsibility.Joe from Jaide Health captured it perfectly when he said: “AI cannot feel the pain your users have. It can help meet their goals, but it will not get you that deep understanding.”There is still no replacement for sitting with a frustrated healthcare customer who cannot get their clinical data into your system, or a creator on YouTube who feels the algorithm is punishing their art, or a devops engineer staring at an RCA output that feels 20 percent off.Every PM knows this feeling: the moment when all signals point one way, but your gut tells you the data is incomplete or misleading. This is the craft that AI does not have.Why judgment becomes even more important in an AI worldDavid, who runs product at a regulated health company, said something incredibly important: “Knowing what great looks like becomes more essential, not less. The PM's that thrive in AI are the ones with great product sense.”This is counterintuitive for many. But when the operational work becomes automated, the differentiation shifts toward taste, intuition, sequencing, and prioritization.Lauren asked the million dollar question. “How are we going to train junior PMs if AI is doing the legwork. Who teaches them how to think.”This is a profound point. If AI closes the gap between junior and senior PMs in execution tasks, the difference will emerge almost entirely in judgment. Knowing how to probe user problems. Knowing when a feature is good enough. Knowing which tradeoffs matter. Knowing which flaw is fatal and which is cosmetic.AI is incredible at writing a PRD. AI is terrible at knowing whether the PRD is any good.Which means the future PM becomes more strategic, more intuitive, more customer obsessed, and more willing to make thoughtful bets under uncertainty.2. The New AI Literacy: What PMs Must Know by 2026I asked the panel what AI literacy actually means for PMs. Not the hype. Not the buzzwords. The real work.Instead of giving gimmicky answers, the discussion converged on a clear set of skills that PMs must master.Skill 1: Understanding context engineeringDavid laid this out clearly: “Knowing what LMS are good at and what they are not good at, and knowing how to give them the right context, has become a foundational PM skill.”Most PMs think prompt engineering is about clever phrasing. In reality, the future is about context engineering. Feeding models the right data. Choosing the right constraints. Deciding what to ignore. Curating inputs that shape outputs in reliable ways.Context engineering is to AI product development what Figma was to collaborative design. If you cannot do it, you are not going to be effective.Skill 2: Evals, evals, evalsRami said something that resonated with the entire panel: “Last year was all about prompts. This year is all about evals.”He is right.• How do you build a golden dataset.• How do you evaluate accuracy.• How do you detect drift.• How do you measure hallucination rates.• How do you combine UX evals with model evals.• How do you decide what good looks like.• How do you define safe versus unsafe boundaries.AI evaluation is now a core PM responsibility. Not exclusively. But PMs must understand what engineers are testing for, what failure modes exist, and how to design test sets that reflect the real world.Lauren said her PMs write evals side by side with engineering. That is where the world is going.Skill 3: Knowing when to trust AI output and when to override itTodd noted: “It is one thing to get an answer that sounds good. It is another thing to know if it is actually good.”This is the heart of the role. AI can produce strategic recommendations that look polished, structured, and wise. But the real question is whether they are grounded in reality, aligned with your constraints, and consistent with your product vision.A PM without the ability to tell real insight from confident nonsense will be replaced by someone who can.Skill 4: Understanding the physics of model changesThis one surprised many people, but it was a recurring point.Rami noted: “When you upgrade a model, the outputs can be totally different. The evals start failing. The experience shifts.”PMs must understand:• Models get deprecated• Models drift• Model updates can break well tuned prompts• API pricing has real COGS implications• Latency varies• Context windows vary• Some tasks need agents, some need RAG, some need a small finetuned modelThis is product work now. The PM of 2026 must know these constraints as well as a PM of the cloud era understood database limits or API rate limits.Skill 5: How to construct AI powered prototypes in hours, not weeksIt now takes one afternoon to build something meaningful. Zero code required. Prompt, test, refine. Whether you use Replit, Cursor, Vercel, or sandboxed agents, the speed is shocking.But this makes taste and problem selection even more important. The future PM must be able to quickly validate whether a concept is worth building beyond the demo stage.3. Why Building AI Products Speeds Up Some Cycles and Slows Down OthersThis part of the conversation was fascinating because people expected AI to accelerate everything. The panel had a very different view.Fast: Prototyping and concept validationLauren described how her teams can build working versions of an AI powered Root Cause Analysis feature in days, test it with customers, and get directional feedback immediately.“You can think bigger because the cost of trying things is much lower,” she said.For founders, early PMs, and anyone validating hypotheses, this is liberating. You can test ten ideas in a week. That used to take a quarter.Slow: Productionizing AI featuresThe surprising part is that shipping the V1 of an AI feature is slower than most expect.Joe noted: “You can get prototypes instantly. But turning that into a real product that works reliably is still hard.”Why. Because:• You need evals.• You need monitoring.• You need guardrails.• You need safety reviews.• You need deterministic parts of the workflow.• You need to manage COGS.• You need to design fallbacks.• You need to handle unpredictable inputs.• You need to think about hallucination risk.• You need new UI surfaces for non deterministic outputs.Lauren said bluntly: “Vibe coding is fast. Moving that vibe code to production is still a four month process.”This should be printed on a poster in every AI startup office.Very Slow: Iterating on AI powered featuresAnother counterintuitive point. Many teams ship a great V1 but struggle to improve it significantly afterward.David said their nutrition AI feature launched well but: “We struggled really hard to make it better. Each iteration was easy to try but difficult to improve in a meaningful way.”Why is iteration so difficult.Because model improvements may not translate directly into UX improvements. Users need consistency. Drift creates churn. Small changes in context or prompts can cause large changes in behavior.Teams are learning a hard truth: AI powered features do not behave like typical deterministic product flows. They require new iteration muscles that most orgs do not yet have.4. The PM, Eng, UX Trifecta in the AI EraI asked whether the classic PM, Eng, UX triad is still the right model. The audience was expecting disagreement. The panel was surprisingly aligned.The trifecta is not going anywhereRami put it simply: “We still need experts in all three domains to raise the bar.”Joe added: “AI makes it possible for PMs to do more technical work. But it does not replace engineering. Same for design.”AI blurs the edges of the roles, but it does not collapse them. In fact, each role becomes more valuable because the work becomes more abstract.• PMs focus on judgment, sequencing, evaluation, and customer centric problem framing• Engineers focus on agents, systems, architecture, guardrails, latency, and reliability• Designers focus on dynamic UX, non deterministic UX patterns, and new affordances for AI outputsWhat does changeAI makes the PM-Eng relationship more intense. The backbone of AI features is a combination of model orchestration, evaluation, prompting, and context curation. PMs must be tighter than ever with engineering to design these systems.David noted that his teams focus more on individual talents. Some PMs are great at context engineering. Some designers excel at polishing AI generated layouts. Some engineers are brilliant at prompt chaining. AI reveals strengths quickly.The trifecta remains. The skill distribution within it evolves.5. The Biggest Risks AI Introduces Into Product DevelopmentWhen we asked what scares PMs most about AI, the conversation became blunt and honest. Risk 1: Loss of user trustLauren warned: “If people keep shipping low quality AI features, user trust in AI erodes. And then your good AI product suffers from the skepticism.”This is very real. Many early AI features across industries are low quality, gimmicky, or unreliable. Users quickly learn to distrust these experiences.Which means PMs must resist the pressure to ship before the feature is ready.Risk 2: Skill atrophyTodd shared a story that hit home for many PMs. “Junior folks just want to plug in the prompt and take whatever the AI gives them. That is a recipe for having no job later.”PMs who outsource their thinking to AI will lose their judgment. Judgment cannot be regained easily.This is the silent career killer.Risk 3: Safety hazards in sensitive domainsDavid was direct: “If we have one unsafe output, we have to shut the feature off. We cannot afford even small mistakes.”In healthcare, finance, education, and legal industries, the tolerance for error is near zero. AI must be monitored relentlessly. Human in the loop systems are mandatory. The cycles are slower but the stakes are higher.Risk 4: The high bar for AI compared to humansJoe said something I have thought about for years: “AI is held to a much higher standard than human decision making. Humans make mistakes constantly, but we forgive them. AI makes one mistake and it is unacceptable.”This slows adoption in certain industries and creates unrealistic expectations.Risk 5: Model deprecation and instabilityRami described a real problem AI PMs face: “Models get deprecated faster than they get replaced. The next model is not always GA. Outputs change. Prompts break.”This creates product instability that PMs must anticipate and design around.Risk 6: Differentiation becomes hardI shared this perspective because I see so many early stage startups struggle with it.If your whole product is a wrapper around an LLM, competitors will copy you in a week. The real differentiation will not come from using AI. It will come from how deeply you understand the customer, how you integrate AI with proprietary data, and how you create durable workflows.6. Actionable Advice for Early and Mid Career PMsThis was one of my favorite parts of the panel because the advice was humble, practical, and immediately useful.A. Develop deep user empathy. This will become your biggest differentiator.Lauren said it clearly: “Maintain your empathy. Understand the pain your user really has.”AI makes execution cheap. It makes insight valuable.If you can articulate user pain precisely.If you can differentiate surface friction from underlying need.If you can see around corners.If you can prototype solutions and test them in hours.If you can connect dots between what AI can do and what users need.You will thrive.Tactical steps:• Sit in on customer support calls every week.• Watch 10 user sessions for every feature you own.• Talk to customers until patterns emerge.• Ask “why” five times in every conversation.• Maintain a user pain log and update it constantly.B. Become great at context engineeringThis will matter as much as SQL mattered ten years ago.Action steps:• Practice writing prompts with structured context blocks.• Build a library of prompts that work for your product.• Study how adding, removing, or reordering context changes output.• Learn RAG patterns.• Learn when structured data beats embeddings.• Learn when smaller local models outperform big ones.C. Learn eval frameworksThis is non negotiable.You need to know:• Precision vs recall tradeoffs• How to build golden datasets• How to design scenario based evals for UX• How to test for hallucination• How to monitor drift• How to set quality thresholds• How to build dashboards that reflect real world input distributionsYou do not need to write the code.You do need to define the eval strategy.D. Strengthen your product senseYou cannot outsource product taste.Todd said it best: “Imagine asking AI to generate 20 percent growth for you. It will not tell you what great looks like.”To strengthen your product sense:• Review the best products weekly.• Take screenshots of great UX patterns.• Map user flows from apps you admire.• Break products down into primitives.• Ask yourself why a product decision works.• Predict what great would look like before you design it.The PMs who thrive will be the ones who can recognize magic when they see it.E. Stay curiousRami's closing advice was simple and perfect: “Stay curious. Keep learning. It never gets old.”AI changes monthly. The PM who is excited by new ideas will outperform the PM who clings to old patterns.Practical habits:• Read one AI research paper summary each week.• Follow evaluation and model updates from major vendors.• Build at least one small AI prototype a month.• Join AI PM communities.• Teach juniors what you learn. Nothing accelerates mastery faster.F. Embrace velocity and side projectsTodd said that some of his biggest career breakthroughs came from solving problems on the side.This is more true now than ever.If you have an idea, you can build an MVP over a weekend. If it solves a real problem, someone will notice.G. Stay close to engineeringNot because you need to code, but because AI features require tighter PM engineering collaboration.Learn enough to be dangerous:• How embeddings work• How vector stores behave• What latency tradeoffs exist• How agents chain tasks• How model versioning works• How context limits shape UX• Why some prompts blow up API costsIf you can speak this language, you will earn trust and accelerate cycles.H. Understand the business deeplyJoe's advice was timeless: “Know who pays you and how much they pay. Solve real problems and know the business model.”PMs who understand unit economics, COGS, pricing, and funnel dynamics will stand out.7. Tom's Takeaways and What Really Matters Going ForwardI ended the recording by sharing what I personally believe after moderating this discussion and working closely with a variety of AI teams over the past 2 years.Judgment becomes the most valuable PM skillAs AI gets better at analysis, synthesis, and execution, your value shifts to:• Choosing the right problem• Sequencing decisions• Making 55 45 calls• Understanding user pain• Making tradeoffs• Deciding when good is good enough• Defining success• Communicating vision• Influencing the orgAgents can write specs.LLMs can produce strategies.But only humans can choose the right one and commit.Learning speed becomes a competitive advantageI said this on the panel and I believe it more every month.Because of AI, you now have:• Infinite coaches• Infinite mentors• Infinite experts• Infinite documentation• Infinite learning loopsA PM who learns slowly will not survive the next decade. Curiosity, empathy, and velocity will separate great from goodMany panelists said versions of this. The common pattern was:• Understand users deeply• Combine multiple tools creatively• Move quickly• Learn constantlyThe future rewards generalists with taste, speed, and emotional intelligence.Differentiation requires going beyond wrapper appsThis is one of my biggest concerns for early stage founders. If your entire product is a wrapper around a model, you are vulnerable.Durable value will come from:• Proprietary data• Proprietary workflows• Deep domain insight• Organizational trust• Distribution advantage• Safety and reliability• Integration with existing systemsAI is a component, not a moat.8. Closing ThoughtsHosting this panel made me more optimistic about the future of product management. Not because AI will not change the job. It already has. But because the fundamental craft remains alive.Product management has always been about understanding people, making decisions with incomplete information, telling compelling stories, and guiding teams through ambiguity and being right often.AI accelerates the craft. It amplifies the best PMs and exposes the weak ones. It rewards curiosity, empathy, velocity, and judgment.If you want tailored support on your PM career, leadership journey, or executive path, I offer 1 on 1 career, executive, and product coaching at tomleungcoaching.com.OK team. Let's ship greatness. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit firesidepm.substack.com
Featuring an interview with Dr Matthew Lunning, including the following topics: Reflection on the advances made in chimeric antigen receptor (CAR) T-cell therapy (0:00) Overview of the CAR T-cell therapy administration process (4:40) Opportunities for referral for CAR T-cell therapy (10:05) Selection of a CAR T-cell therapy based on patient characteristics (16:09) Sequencing of CAR T-cell therapy for various non-Hodgkin lymphomas (23:23) Safety regulations and mitigation strategies for adverse events (30:36) Case: A woman in her early 80s with relapsed/refractory (R/R) diffuse large B-cell lymphoma receives lisocabtagene maraleucel (36:16) Case: A man in his early 60s with R/R mantle cell lymphoma receives brexucabtagene autoleucel (43:09) Case: A man in his early 60s with R/R multiple myeloma receives ciltacabtagene autoleucel (49:09) CME information and select publications
Join Professor Laura Coates and Phillip Mease as they discuss the top publications in the world of PsA. This month, the conversation covered the ‘the effectiveness and safety of upadacitinib with secukinumab and adalimumab' and ‘the efficacy of long-term treatment with risankizumab across the updated GRAPPA domains and key related conditions of PsA'.
David: Hi, and welcome to the podcast. In today's episode, co host Jay McFarland and I will continue our discussion about the AI Approach to Multiply Your Sales. This is part four in our series, and today we'll be talking about learning, segmenting, and the Three Ds. Welcome back, Jay. Jay: Hey, thank you so much, David. I really, really enjoyed this. I know I’ve said that in previous podcasts, but it’s true. After each one, I’ve gone into my own business and I’m like, okay, I got to apply this and apply that because these conversations are of such value. So I appreciate your time. I love this. And hopefully it’s been helpful to everybody else. David: I’m glad, I feel the same way, and I’m really looking at this almost like a mini-course. If people were to put together these four episodes and say, “How much of this stuff am I doing in my business?” You can probably implement some things very quickly that can probably help you get some great results. Jay: 100%. David: All right, so let’s do the quick review. And again, what we’re talking about here is we asked AI what will help you to multiply your business because that’s been a focus of our conversations recently. AI came back with some different responses, and then we’re talking about what AI says and how we’re able to help implement those things in business with our clients. And so let’s just recap. Number one was refine your target audience. Number two, develop a compelling value proposition. Number three, optimize your marketing channels. That was our first episode on that topic. In episode two, we covered points four, five, and six. Number four was enhance your customer experience. Number five, implement a referral program. And number six, leverage the power of content marketing. In episode three of this series, we hit utilize upselling and cross selling strategies, which was number seven. Analyze and optimize your sales funnel, which was number eight, and invest in customer relation management software, CRM, which was number nine. Now we’re going to be doing 10, 11, and 12. Eleven and 12 are really bonus because originally I asked it for 10 and then I realized that doesn’t break out well if you’re doing three in a podcast. So I went back to the AI and I said, give me two more. And it did. So we’ll be talking about numbers 11 and 12 in this podcast as well. So number 10 in the list of things that AI says will help you to multiply your sales is: 10: Continuous learning and adaptation. Stay updated with industry trends, attend relevant workshops or conferences, and be open to adapting your sales strategies to meet changing market demands. Well spoken AI! Continuous education. It’s a good call! Jay: It is, and some professions actually require it. But again, that continuous education is often on a service or a specialty or things like that. It’s not really on customer service or the technology or things like that. I feel like in that regard, so many of us are a hamster on a wheel. You know, we’re just trying to keep up with what today is giving us. We’re putting grease on the squeaky wheel and we don’t have time to really think about staying up on, you know, all the latest trends and those kind of things. David: Yeah. And a lot of people just don’t like continuing education, because they feel like so much of it is platitudes. It’s like, I already know this stuff. I already know it, right? But knowing what to do is very different than knowing how to do it. And that’s really what I’ve been trying to differentiate in this series of podcasts is that, yes, these are great statements. Continuous learning. That sounds great. But what are you learning? Are you learning things that you can implement immediately? Are you putting in place processes that will allow you to start getting results right away so you can gauge those results and then adapt, change, or tweak the process as you go to make sure that it’s working for you? So once again, we’re focusing on all the little details that make these general recommendations profitable. Jay: You know, I don’t know where I get it. I think I get it from my dad, but I am on a never ending quest to make things more efficient. I am always looking for the next software, the next device, the next system. I’ve done it since I was 15. My first job was in a burger barn at an amusement park. And I was watching how they put everything on the grill and what they would do is they’d cover the whole grill with burgers And then they would flip them all at the same time, and then they would pull them all off at the same time, and while they’re preparing them, the grill is sitting there empty. And so the line would move, and then it would stop, and I’m like, this is crazy. Put down two rows, wait a second, put down two, put down two, and at 15, I changed the whole thing. I’ve been doing that stuff my whole life, so I I love the tech. I love the next thing. And I’ll spend weeks and months finding the right thing knowing that it’s going to improve my business for years to come. David: Yeah, and that really goes to the point. The words that the AI used , it said continuous learning and adaptation. Jay: Yes. David: And what you’re talking about there is adaptation and implementation. Adapting the system to be able to get the result that you want Jay: Yes. David: So that everything gets better for everybody. Beautiful thing. Jay: Yeah, KPIs, Key Performance Indicators, that’s kind of what we use nowadays. And we’ve talked about this in previous podcasts, understanding every aspect of your business and knowing how you can influence it and adapt it. Because you can’t adapt, if you don’t know the reality of what’s going on. And I’ve worked for so many companies where management has no clue what’s happening on the front lines. And so we’re asking them, we’re begging them to adapt. Or they have software built by engineers who aren’t on the front line and we’re pulling our hair out because it doesn’t answer any questions. It makes life harder for us. David: Right. And unfortunately, a lot of it boils down to not knowing what to do and not knowing how to do it. “Yes, this is a problem, but I don’t know how to fix it. I don’t have time to think about how to fix it. Therefore, soldier on, keep moving, keep working. Good luck with that.” And so much of this, and even this point, continuous learning and adaptation is about identifying those small hinges that swing the big doors. And so much of what we do with our clients is about doing just that. Finding what is a small and obvious fix to a problem that could have been plaguing a company for literally months or years. You fix it in 10 minutes with a one sheet piece of paper that says, “Do it this way,” and they implement it, and they immediately start to see better results. So, I think in terms of, okay, this is what AI suggests, this is how we end up getting it done. So that’s number 10, continuous learning and adaptation. 11. Targeted Marketing Campaigns. Develop targeted marketing strategies tailored to specific customer segments. This approach ensures that your marketing efforts resonate deeply with your intended audience, leading to higher conversion rates. Once again, a lot of buzzwords in that sentence. A lot of really good recommendations in that sentence, but a lot of confusion too. Jay: Yeah, absolutely. Can I brag for a minute? David: Please do. Jay: I want to brag for a minute. So a lot of people know that I’ve just recently started an accounting firm that focuses on day traders and they’re taxes. And we’ve spent over a year and a half with my current company and my last company working on keywords to make sure we get the right leads from Google advertising. And David, in the last four months, I have not had one lead that is not right in the strike zone. Now, think about that. Think, I mean, that is unbelievable to me. That, and they, you know, we’re in constant contact with the company that we use. And every month they’re like, okay, how many leads were outside? What do we need to adjust? And I’m like, just keep pitching ’em, man, because they are right there. And the beauty of that is, all we have to do is adjust the volume. Right? Certain times of the year we crank that volume up, and certain times of the year we crank it down. And, wow! When we have the secret sauce, I mean, everything else is just gravy at that point. David: Exactly. And what you’re talking about really ties back to point three, earlier in our conversation, which is about optimizing your marketing channels. Jay: Right, right. David: When you’re able to do that, and you combine that with what we’re talking about here in number 11, which is targeted marketing campaigns, it’s a double whammy. Because now you are getting to the right people through the stuff that you’re doing with your SEO. And your communication is better, which is something we also talked about in the first episode in this four part series. And now, when you talk about targeted marketing campaigns, to me what that means is you’re taking the communications that we’ve perfected, creating value in the communications like we talked about in a previous episode, and now you’re sequencing that communication. That’s how we describe it to our clients inside our program. You’re sequencing your communication. You’re putting together a series of messages that go out in a specific order, in a specific timeframe, so that you’re getting the information in front of them when they need it most. To me, a targeted marketing campaign is about doing that. You’re getting the right message out to the right people at the right time. Using the right targeted marketing vehicle. Jay: I love that. Sequencing the information. That makes a lot of sense to me. And I think understanding that in first contact, they might not understand your product or the need for it. But we all know if they see you a couple times, you know, what is it? You used to hear they have to see you seven times, you know, a billboard, a TV ad, or whatever that is? Meeting them where they’re at. Instead of trying to force them to be where you want them to be. It sounds to me like a great way to go. David: Yeah, no question. I remember, I think it was in the Guerrilla Marketing book, he was talking about the fact that somebody had to be exposed to your message nine times before they’d be ready to buy. And at that point, I extrapolated for myself. I said, well, what if they only see one out of every three messages I put out? To me, that means I need to do nine times three, 27. I need to get out to them 27 times before they’re going to be ready to make a buying decision. And that’s really the essence of what sequencing communication is. A lot of times we feel the need to try to tell everybody everything up front, before they even know who we are. And their eyes glaze over and like, Oh, this is too much. This person’s too full of hot air. I’m moving on. And when you sequence your communication properly, you’re dripping it out a little bit at a time. You’re giving them a little bit this time and a little more the next time, a little more the following time. And each part of it reveals a different aspect of your approach. A different aspect of the way that you do things, and the benefits that you bring to them. And if number one didn’t completely resonate, maybe number two will, and maybe number four will, and maybe number seven will. And the ones in between, if it’s good, useful information, and it’s creating value for them, they’ll still be happy to see it. They’ll be happy to look at it. But then, when you get to the ones that really resonate with them, they’re going to respond. Jay: Yeah, absolutely. And I love how you said they don’t know who we are, but I would also flip that. We don’t know who they are yet, right? And so, like you said, we’re kind of dividing their possible interest into this sequencing. And hopefully, at some point, we’re going to land on who they are and what their needs are in that moment. David: Exactly. And so much of it really becomes fun when you’re taking an approach like this. And I use the word fun a lot when I’m talking with my clients. Because I figure if what we’re doing is not actually fun, we’re not doing it right. Because if it’s miserable, if it’s a big old slog and we can’t stand it, Let’s face it, they’re not going to do it. But when you’re able to make it fun by taking the appropriate action with the appropriate people at the appropriate time, everything gets a lot easier and a lot more fun. Jay: Absolutely, absolutely. David: All right, so number 12, this is the last one on our list. And this is: 12. Data Driven Decision Making. Leverage data analytics to understand customer behavior, preferences and buying patterns. Data driven insights empower you to make informed decisions, refine your strategies, and optimize sales processes. Many words. Jay: Yeah, and again, how do you extrapolate that out into your own business? I know this is something we work on constantly. I don’t think there’s ever going to be a point where you’re like, “okay, got that one done,” right? It’s got to be constant. David: Yeah, and once again, going back to the idea of simplification, which is a really big part of what we do with people, boiling it down to its essentials. Data driven decision making, to me, and this is what I refer to as the 3 D’s at the beginning of this podcast, data driven decisions, right? To me, that means that you are making your decisions based on the right information, the actual information, not what we think might be right, not what we feel, oh, I feel like I should do this. What does the data say? What’s working well? What are the things that we’ve done in the past that have worked well? What are the things we’ve done in the past that have not worked as well? How can we continue to replicate the things that we did that did well? Do adaptations on those, to be able to continue to move that needle forward. How can we avoid the mistakes that we made in the past based on what we’ve done and the responses that we’ve gotten? To me, that is the essence of data driven decision making. And if you look again at the AI description, leverage data analytics to understand customer behavior. That just means looking at what are the customers doing based on what you’re sending out? Leverage data analytics to understand customer behavior, preferences, and buying patterns. Okay, so that’s all the same. Data driven insights empower you to make informed decisions. Right, your decisions are now informed. They’re not just decisions, right? And then it says, refine your strategies and optimize sales processes. It allows you to do all of that. So, I would argue that this one, data driven decision making, is essentially a combination of all of the above. Because when you’re implementing the things that we talked about over this series of podcasts, and you’re gauging the results, you’re tracking it down, you’ve got the tracking sheets or however it is that you’re keeping track of what’s going on, and you’re making the decisions based on, not what you think is going to work or what you think might work, but what actually is working, everything becomes a lot easier. Jay: Yeah, absolutely. Can I give you a bad example of not using data? David: Sure, I love bad examples!. Jay: So, I worked for a national pizza chain. I’ll give you a hint, Pizza Pizza. Still family owned, even till today. And one day the daughter of the owner came up with this brilliant idea that people wanted bigger pizzas. I don’t know if you remember this. It was called Bigger is Better. So they forced every franchisee to go out and retrofit all of their ovens. Buy new pans. The whole thing probably cost five grand per business to just do this. And they of course marketed behind it. Guess where all those pans are? They’re sitting on top of the walk in refrigerators. Because there was no data, it was not driven by anything more than a feeling. And it was just the most ridiculous effort I’ve ever seen. And that’s some of the problems you can get into with a family run business, because you are making gut feeling decisions instead of looking at the data. David: Yeah, I’d love to say it’s just family run businesses, but wow, New Coke. Two words, right? Jay: Yeah. David: This kind of thing just happens everywhere. And some things just seem like a really good idea. Hey, wow. If they like this one, they’ll probably like that one when you say it out loud. Sure. It seems reasonable. And if the marketing was right and if the people wanted it, then that would have worked, but we just don’t know. So data driven decision making is also a big one. All right. So in terms of sort of wrapping this up, because we’ve been doing this now over a period of four podcasts over four weeks. I feel like we touched on a lot of really good topics. I feel like we were able to dive deep in terms of some of the how, of how to do these things. And I’m hoping that the people who have actually paid attention through each of these episodes got some really solid ideas on specific things they can do to grow their sales and profits. If that’s the case, and if you’d like to have a conversation about how we can help really just Implement this stuff inside your business, go to Topsecrets.com/call. Let’s have a conversation. See if we can help. If we can, we’ll let you know. If we can’t, we’ll let you know that too. There is zero pressure on these calls. It’s about identifying the primary areas where you need help, providing recommendations on what you can do and how you can do it, and then saying, all right, if you want to do it by yourself, you can do that. If you want to do it with us, you can do that, but you have the option. So hopefully that makes sense. And if you’d like to do it, TopSecrets.com/call. Jay: Yeah, I love it. And I’ll just kind of add my feedback on this series of podcasts. I’ve learned a tremendous amount. I’ve applied a bunch. But one of the things that stands out to me, is that you don’t have to do it alone. And I think sometimes we see it as weakness, right? I should be able to run this all. I should be able to do it all. Yeah, maybe, maybe. But there are people who have gone before you. There are people who’ve spent, David, how many years have you spent doing this and refining this and, and talking to customers? So, I mean, it’s just a great service. Again, just speaking out loud about it has made such a difference for me. So, I’m a huge fan of what you do and I hope people will recognize your sincerity, that it is just a call, and you do have a very strong desire to help. And you help a lot of people. David: Well, thank you. And we never try to push anyone into our programs. All we’re looking to do is we’re looking for the right fit. If you are a smart, focused, motivated business owner, and you are determined to get from here to there, then we probably want to work together. If you’re not good with making decisions, if you’re kind of iffy or wishy washy, then it’s probably not going to be a good fit. And in many of the calls, we can get two thirds of the way through the call and recognize pretty early on it’s not a good fit. At which point we’ll say, yeah, I don’t think we can help you. You know, maybe you can try this resource or that resource. So, it’s really not about us trying to sell you into anything. If we can work together, great. If we can’t, that’s perfectly fine too because we’ll know, right? We’ll have the conversation, and we’ll both know! You’ll know, “oh, it’s not a good fit,” I’ll know, it’s not a good fit. And you get closure, which is beautiful. If you’ve been thinking about scheduling a call and just haven’t, there’s no closure, right? Have the call. It’ll be a thumbs up or a thumbs down. Either way, it’s great. You’ll have a great experience. We’ll have a great conversation, and I hope you do it. Jay: Yeah, and listen, there’s no reason to be a salesperson when your product is great, and yours is. So, David, I love our conversations, and thank you so much for your time today. David: Thank you, Jay. Ready to Multiply Your Sales? If so, check out the five primary ways we help promotional product distributors grow: Just Getting Started? If you (or someone on your team) is just getting started in promotional products sales, learn how we can help. Need Clients Now? If you're already grounded in the essentials of promotional product sales and just need to get clients now, click here. Want EQP/Preferential Pricing? Are you an established industry veteran doing a significant volume of sales? If so, click here to get End Quantity Pricing from many of the top supplier lines in the promo industry. Time to Hire Salespeople? If you want to hire others to grow your promo sales, click here. Ready to Dominate Your Market? If you're serious about creating top-of-mind-awareness with the very best prospects in your market, schedule a one-on-one Strategy Session here.
As a property management business owner, you likely work with seasoned investors who are always looking for new ways to build and preserve their wealth and assets. In this episode of the #DoorGrowShow, property management growth expert Jason Hull sits down with Alan Porter to discuss how to reveal the powerful financial strategies the wealthy and large financial institutions use and how you can apply them. You'll Learn [01:09] Alan's Inspiration for Uncovering Financial Secrets [08:38] Learning Financial Planning Strategies 90% of People Don't Know [12:25] How to Get Started on the Path to Tax-Free Retirement [15:43] Strategies For Property Managers and Their Clients Quotables "The one thing you can always trust is for everybody to look out for their own self-interest." "If your own self-interest is in alignment with their interests, then that's a win-win. Otherwise, someone's gonna lose." "If you don't have a plan, make one. But you've got to have a plan and improve on it all the time." Resources DoorGrow and Scale Mastermind DoorGrow Academy DoorGrow on YouTube DoorGrowClub DoorGrowLive Transcript Alan Porter (00:00) I teach people to think outside the box, conventional financial planning, and show them the strategies that the wealthy and banking institutions have been using for years. Now, I show people how to become their own bank. Jason Hull (00:10) All right, welcome everybody. I am Jason Hull, the founder and CEO of DoorGrow, the world's leading and most comprehensive coaching and consulting firm for long-term residential property management entrepreneurs. For over a decade and a half, we have brought innovative strategies and optimization to the property management industry. We have spoken to thousands of property management business owners, coached, consulted, cleaned up hundreds of businesses. Alan Porter (00:26) Thank Jason Hull (00:35) helping them add doors, improve pricing, increase profit, simplify operations. And we run the leading property management mastermind in the industry. At DoorGrow, we believe good property managers can change the world and that property management is the ultimate high trust gateway to real estate deals, relationships, and residual income. We are on a mission to transform property management business owners and their businesses. We want to transform the industry. eliminate the BS, build awareness, change perception, expand the market, and help the best property management entrepreneurs win. Now, let's get into the show. So my guest today is Alan Porter of Strategic Wealth Strategies. Welcome, Alan. Alan Porter (01:16) Well, thank you for having me on. Jason Hull (01:18) Yeah, glad to have you. And we're going to be talking about, he's going to be sharing how to reveal the powerful financial strategies, the wealthy use, how you can apply them to. Alan will be uncovering the IRS approved playbook for retiring completely tax free, explain the millionaire tax strategies business owners use to keep more of what they earn and break down Wall Street myths to show how to build lasting wealth without market volatility. So Alan. Again, welcome to the show and why don't we kick things off by give us a little bit of background on you. How did you get into entrepreneurism, into business and give us a little bit of backstory so we understand how this all came to be. Alan Porter (02:00) Well, I never thought I'd be doing this. I retired from the military back in 1993. I was a Blackhawk instructor pilot and I told everybody I had a safe landing for every takeoff and I dodged all the bullets and I had a great career. And I got enrolled in the real estate mortgage business after that up till about 2008. I've had some tragic things happen to my family. In 2009, live in Little, mean Fayetteville, North Carolina. My son lived in Little Rock, Arkansas with his wife, Lynn. She was 39 and they had two little girls that were seven and four. Jason Hull (02:19) in 2009. Alan Porter (02:28) Well, we went down there for Christmas in 2009, but my son had been 100 % disabled for three years and still not getting the disability. And January 5th changed my entire life. His wife, Lynn, called me up. said, Alan, I've been diagnosed with stage four pancreatic cancer and they've given me six months to live. Of course we were all devastated, but there's a huge financial problem that's developed in my son's family because there's no money coming in. Jason Hull (02:28) Well, we went down there for business in 2009, but my son had been 100 % disabled for three years and still not in a disability. Wow. And January 5th changed my entire life. His wife Lynn called me up, she said, Alan, I've been diagnosed with stage 4 pancreatic cancer and they've given me six months to live. Of course, we were all devastated. Yeah, I bet. there's huge financial problem that's developed in my son's family because of the money coming in. Alan Porter (02:55) I'm helping them out, but I don't know for how long Jason Hull (02:55) I'm helping him out, but I don't help him. Alan Porter (02:56) until I'm gonna have to sell my house or do something. But I was like 99 % of the people out there, Jason, that thought life insurance was a death product that you had to die to benefit from it. Well, little did I know she had a terminal illness right or her life insurance policy that she could access within one year of diagnosis of this deadly disease and was completely tax free, which I knew nothing about. It was hundreds of thousands of dollars. Jason Hull (02:58) Yeah. Really? Alan Porter (03:21) And if it had not been for that, my son would be bankrupt and it took a huge financial strain off of me. Jason Hull (03:25) Yeah. Well, long story short, died a year later, so I moved my son back here to Fayetteville, North Carolina. But about a year after that, my daughter's an oncology nurse, and her husband's a doctor at Woodbrook and Raleigh, North Carolina, and just gave birth to my third grandson. And she was diagnosed with breast cancer, and it was very bad. We didn't think she was going to live. Well, now in 2023, she's been 12 years cancer free, but she also was diagnosed with Graves' disease, thyroid eye condition. Alan Porter (03:26) Well, to a long story short, she died a year later. So I moved my son back here to Fayetteville, North Carolina. But about a year after that, my daughter, who's an oncology nurse and her husband's a doctor, they live up in Raleigh, North Carolina, had just given birth to my third grandson. And she was diagnosed with breast cancer and it was very bad. We didn't think she was going to live. Well, now in 2023, she'd been 12 years cancer free, but she also was diagnosed with Graves disease and thyroid eye condition. There's only one treatment for it. It's not a cure-all for anything, but Jason Hull (03:51) And there's only one treatment for it. It's not a cure-all. Alan Porter (03:55) it's a treatment. It's an infusion, eight infusions of this drug is called Tepezza I believe. The first one was like $32,000. The last one was almost a quarter of a million dollars. That was in May of 2023. On January of 2024, the thyroid eye condition came back. In February, she went to the doctor. The doctor said, Nicole, I'm sorry, there's nothing we can do until you go blind and then we can operate. I'm thinking, man, what a prognosis. Jason Hull (03:55) my Yeah. ⁓ Alan Porter (04:21) So we tried to get her a study at Duke. She didn't qualify for that because she had already taken the Tepezza But April did get her into the Mayo Clinic in Rochester, Minnesota. But basically there's nothing they can do for her. She was up there for about four days for testing and consultation. But basically, like I said, there's nothing they can do for her. They got a drug that may be 50 % effective. It's not improved by insurance. And believe it or not, it's even more expensive than the Tepezza is. And it's just, I mean, so. Jason Hull (04:39) Yeah. Yeah. Alan Porter (04:51) So both of my kids are living day to day in misery. And when I got started in this, knew, like I said, these things, because I was to have a very successful real estate mortgage business. And I said, these financial strategies that the insurance companies have, why don't people know about this? These are the greatest financial vehicles out there. People tell me, well, listen to Suzy Orman and Dave Ramsey, insurance is not a good investment. Well, first off, it's not an investment. Jason Hull (04:54) When I got started in this, knew, like I said, these things, because I was very successful in estate in my early years. I said, these financial strategies that the insurance companies have, why don't people know about this? These are the greatest financial vehicles out there. People tell me, listen, as soon as you arm it today, Ramsey, insurance is not a good investment. Well, first off, it's not an investment. Alan Porter (05:18) It's an asset class all of its own. There's no other financial product that can Jason Hull (05:19) It's an asset class all of itself. There's no other financial product that... Alan Porter (05:23) provide the protection, performance, and benefits of cash value life insurance when properly structured and fixed and fixed indexed annually. And I'll give you one big point. They eliminate or mitigate the risk in retirement that a stock portfolio only compounds. That's absolutely... Let me ask you this. Have you ever heard of sequence of returns risk? Jason Hull (05:23) could provide the protection, performance, and benefits of cash, money, or life insurance. Yeah. if you have one big point, they eliminate or mitigate the risk in retirement that a stock portfolio only compacts. That's absolutely, let me ask you this, have you ever heard of sequence of returns risk? Sequencing returns? Sequence of returns risk. No. Alan Porter (05:46) Sequence of returns risk. Well, don't feel lonely because 99 % of the people I talk to, to include multi-millionaires that have fee-based advisors. And let's say that you're 65 years of age and you go to retire and you got a million dollars in your stock portfolio. They used to say a 4 % distribution rate was a safe distribution rate to last for 30 years, index for inflation at 3%. Well, my plans go to age 120. They don't cut off in 30 years. Jason Hull (05:50) Well, don't feel lonely because 99 % of the people I talk to include multi-millionaires that have fee-based advisors. let's say that you're 65 years of age and you go to retire. You have a million dollars in your stock portfolio. They used to say a 4 % distribution rate was a safe distribution rate to last for 30 years, index for inflation at 3%. Well, my plans go at age 120. They don't cut off in 30 years. But the problem with that 4 % distribution rate Alan Porter (06:15) But the problem is that 4 % distribution rate, that's Jason Hull (06:19) That's $40,000 a year. And that stock portfolio, that's not guaranteed. What if you have a 10 % loss the first year? now your million dollars goes down to $900,000 minus the $40,000 you took out minus the fees you paid on financial advisor whether you make money or not. And then the next two to three years, 2008 happens again, where you lost 38 to 52%. You never got the money in the fifth year. And when I tell people about this, they're financial advisors, Alan Porter (06:19) $40,000 a year. And that stock portfolio, that's not guaranteed. What if you have a 10 % loss the first year? So now your million dollars goes down to 900,000 minus the $40,000 you took out minus the fees you pay that financial advisor, whether you make money or not. And then the next two to three years, 2008 happens again, where you lost 38 to 52%. You're going to be out of money in the fifth year. And when I tell people about this and their financial advisors, Don't tell them, I mean, they're said, I said, why do you think that is? Jason Hull (06:45) don't tell them. I made letters, I said, why do you think that is? Alan Porter (06:48) It's because they make a fee whether you make money or not. The number one fear in retirement is running out of money before you run out of money. I can eliminate that. Jason Hull (06:49) Because they make a fee, well, if you make money or not. The number one fair return is 20,000 dollars. Yeah, compensation structures are incentive models. And so if their incentive is not to tell you, it's because they're getting paid to not tell you. Well, they're supposed to be fiduciary looking out for their best interest clients. I'm a certified financial financial advisor. Yeah, but regardless, the one thing you can always trust is for everybody to look out for their own self-interest. Oh, you're right there. Alan Porter (06:59) Yeah, exactly right. Well, they're supposed to be fiduciaries looking out for their best interest clients. I'm a certified financial fiduciary. you're right there. Jason Hull (07:18) So if your own self-interest is in alignment with their interests, then that's a win-win. Otherwise, someone's gonna lose. Yeah. It's always the clients. Yeah. Yeah. Okay, well, that's quite the story. how is everybody doing now? Alan Porter (07:26) Yep. And it's always the client. My son looks like he's 85 years old and my daughter's living day to day in pain. Jason Hull (07:43) Yeah, yeah. So you have this burden of trying to figure out how do I take care of them? How do I make sure that, you know, taking care of your kids and, you know, nothing's more stressful emotionally or more motivating for us as a parent than our own kids having it going through a tough time. Yeah. I remember my oldest daughter, she was born with a birth defect that there was a rotation in her gut and she was just always sick, throwing up, stuff like this. Well, she almost died. We didn't know this. got, went and got a scan. Everything was inflamed. They're like, we have to do emergency surgery immediately. And yeah, it was pretty scary as a parent. And they had to like pull her guts out, do surgery, put them back in. And she was a little kid, you know? Now she's my oldest. I mean, she's still my oldest, but now she works for me. and in DoorGrow which is great. But yeah, I remember those times. That's really scary. And I can imagine that's just really a big load on your shoulders. So did this kind of spark you creating the strategic wealth strategies then? Alan Porter (08:30) No. Absolutely, that's my passion for this. I'm very passionate about what I do. It's all about education because people don't know. Jason Hull (08:49) Explain the passion, like what gets you excited about this? Alan Porter (08:53) Well, educating people. That's what I did in the Army. I was an educator. I taught people how to fly. it's just like this, educating people. I teach people to think outside the box, conventional financial planning, and show them the strategies that the wealthy and banking institutions have been using for years. Now, I show people how to become their own bank. I've been doing this for a decade and a half. And why don't everybody doesn't do this? I don't know why. mean, you borrow money from yourself, you pay yourself back compound interest. Jason Hull (09:16) you Alan Porter (09:20) and not the financial institutions and you eliminate the effective interest cost that you pay on the money that you borrow. And people, are you aware of what effective interest cost is? Banks love it. I had a gentleman who wanted to do my debt free for life plan. And I said, well, how much debt do you have? He says, well, we bought a new house a couple of months ago, a couple of car payments, a loan and a credit card. I said, what's the interest rate on your mortgage? He said 2.75. Jason Hull (09:20) Yeah. And people, are you aware? No, what is that? Alan Porter (09:46) I said, what's your effective interest cost on that? He says, well, I don't know what you're talking about, Alan. I said, don't fill it, only most people don't. Fill out my form, we'll do a Zoom conference the following week. I said, you got $461,000 in debt. That's not your problem. The problem is the 49.76 effective interest cost, you're paying on that 2.75 % mortgage. His eyes got real big and he said, Alan, how is that possible? I said, it's not going to get down to the 2.75 until the last couple of months of the mortgage. Jason Hull (10:10) Yeah. ⁓ Alan Porter (10:14) You've got a credit card here that's over 90 % effective interest cost. And even though you've got great credits, your average effective interest cost is over 46%. So my next question to him was, what financial vehicle are you investing in, your 401k or anything else, that gives you a 46 % return on your money? Because 46 cents of every dollar that you pay out goes to compound interest for some financial institution, and that money's gone for you forever. Jason Hull (10:17) and ⁓ Alan Porter (10:38) He said, well, nothing. In fact, I lost 10 % of my 401k. Jason Hull (10:40) Yeah, that'd be hard to find that much. And then my last question was how long does it you to your debts off? I said with my cap three buck of money and a whole lot of insurance policy, 14.17 years past, saving $73,000. And in the 10th year it would be 52 years of bids, and there's over $149,000 in cap Alan Porter (10:43) And then my last question was, how long can it take you to pay your debts off the way you're doing it? I 20 some years. I said, with my tax-free bucket of money and a whole life insurance policy and our software, we're paying all your debts off 14.17 years faster, saving you $73,000 in interest. And in the 10th year, you'll be 52 years of age and there's over $139,000 in a tax-free bucket of money that you can use ⁓ to buy a new car, whatever, college education for your kids. Jason Hull (11:06) you can use uh buy a new car whatever college education for your kids at that point your debt benefits will be $400,000 in tax-free money from the federal bank but think about this you don't have to any more money in this by the time you're 65 there'll be over $400,000 in tax-free money that you can use to supplement your income that does not affect the taxation of social security or the tax and community care part which will be in the thousands per year Alan Porter (11:13) At that point, your debt benefits over $400,000 of tax-free money to protect your family. Think about this. You don't have to put any more money in this. By the time you're 65, there'll be over a quarter of a million dollars in a tax-free bucket of money that you can use to supplement your income that does not affect the taxation of Social Security or the means testing for Medicare Part B, which will be in the thousands per year. You're protected from lawsuits, liens, and judgments, and it eliminates or mitigates all the risk in retirement. This is absolutely great for real estate investors. Jason Hull (11:35) Yeah. Yeah ⁓ Alan Porter (11:42) Because once they build that money up in the cash value of their policy, they can take it, go buy a property, and pay themselves back. I do this all the time. I just bought two new cars in last two years. I pay myself back. I'm going to have tens of thousands of dollars more because I compounded interest for me instead of some financial institution. Jason Hull (12:03) So you said multiple times, like why aren't people doing this? Well maybe you could answer your own question, why aren't people doing this? Alan Porter (12:10) It's lack of education. It ought to be taught in high school, but it's not. I've got college professors with PhD degrees in accounting and finance. They have no idea what I'm talking about. They ask me to teach their classes. Jason Hull (12:20) Yeah, got it. So it was just a lack of education on this. Alan Porter (12:24) That's exactly what it is. Jason Hull (12:25) So, yeah, well, I mean, it sounds like something that everybody should be doing. So how does somebody get started with this or how do they become aware of this or what would you say are the first steps? Alan Porter (12:38) Well, give me a call. I don't charge for my consultation services. That's free. It's an education. I think everybody needs to know these things because it will change their financial future, not only for them, but for their family also and possibly generations to come. at 9-8-5. Jason Hull (12:52) So Alan, it sounds like you've kind of found a passion in this. You really enjoy helping people to be able to figure this out and do this. Alan Porter (13:00) Absolutely. Jason Hull (13:01) So yeah, I think that's noble. I think this is pretty awesome. So for those that are listening to this point, I'm going to read a quick word from our sponsor and then Alan, I'm going have you share your phone number so they can get in touch with you and we can keep talking about it. So this episode is sponsored by KRS Smart Books. So if you're a property manager, are you tired of getting tangled up in numbers? KRS Smart Books has your back. They specialize in property bookkeeping. for small to mid-sized managers who'd rather focus on, well, managing. With over 15 years of experience in real estate accounting, their pros in AppFolio, Yardi, and all the top property management software, trust them to make your monthly reports hassle-free so you can get back to what really matters running your business. Head over to krsbooks.com to book your free discovery call. All right, so Alan, what's the number that they should get? to get in touch with you or to reach you to find out about this. Alan Porter (13:59) You can call me at 910-551-1046, email me at strategicwealth, the number zero at gmail.com. And you can always go to my website, which is www.strategicwealthstrategies.com and you can book appointment there. And I've got a plethora of information on that website. Jason Hull (14:18) What? Great, thanks for sharing. So for those that are listening, some people might listen to this and go, well, that's nice, but Alan probably can only work with people that maybe have a million dollars or that are ultra wealthy or have lots of savings. People will listen to this and say, that's probably not for me. What would you say to that? Alan Porter (14:39) Well, quite frankly, bull I work with everybody. know, I'm for the military. Military people don't make a lot of money. Okay. And I work with them, but I work with regular, regular working people that I mean, I'll give you a perfect example. I asked people, said, why do you contribute to a 401k? They said, well, it's a tax deduction. I said, no, it's a tax compounder. And I thought you don't think tax is going to be higher when you retire. I got another thing coming for you. Jason Hull (14:43) Okay. Right. Alan Porter (15:07) But see, thing is people don't understand. 1 % of people out there don't even think there's a fee in a 401k. A 1 % fee over a 30-year period will reduce your income by one-third. The average fee in a 401k is 2.99%. Now that's by Forbes Magazine and the Laptimes. People have less than two-thirds of their money and then they get hit with taxes anywhere from 20 to over 55%. And they're not prepared for it. They're not prepared for long-term care, which costs right now between $50,000 to $200,000 a year. I can get money for that's tax free for pennies on the dollar. It's just a matter of education. Jason Hull (15:43) So for the property management business owners listening, a lot of them will have sometimes hundreds of clients that are investors and they're wanting to maximize their investments, how would this maybe benefit the property management business owners to be better educated on this and have a strategic partner like you? Alan Porter (16:03) Well, the thing is, you've to have a plan. If you don't have a plan, make one. But you've got to have a plan and improve on it all the time. But it's just like, you know, building up your cash value and borrowing from yourself to buy a property and paying yourself back. That's an absolutely great thing for a real estate investor. And these property managers, I've got health and wellness programs. If you've got employees over 10 employees, understand this. The employer will save anywhere from $500 to $700 a year in FICA taxes. The employee and the employer have 1,100 drugs, prescription drugs, at zero copay. That's 20 to 30 % of healthcare costs. Jason Hull (16:37) Yeah Alan Porter (16:50) I mean, and they also have an accidental indemnity program and that's not for the employer, but they have a revolution health app. They've got the number one telehealth app according to JD Power and associates. It's a plethora of benefits. We have legal club, we have identity shield. It's just all at no net cost to employer and no net cost to the employee. It's the section 125 of the tax program. Jason Hull (17:06) This is all at no net cost reported at no net cost reported. Got it. Got it, interesting. Okay, well cool. Well what else would people generally ask about this or should we make sure that the listeners are aware of related to this? Well, are you... Alan Porter (17:26) Well, are you risk averse? Are you conservative? You know, it's just like when you go to retire and you've got that million dollars in stock portfolio, a 4 % distribution rate, $40,000. If you had a property constructed fixed indexed annuity at, say, age 65, you'd only need approximately $650,000 of that stock portfolio to give you the same $40,000 a year. That's guaranteed for the rest of your life. we're guaranteed. Jason Hull (17:53) New York Heat. ⁓ Alan Porter (17:53) Never to have a loss through the market because we're not tied to the market for our gain. We use indexing strategies and every time that indexing strategy goes up we have increasing income and the older you get the higher the distribution rate is. You can't do that with a stock portfolio. It's not even comparable. Jason Hull (17:59) And every time that index of strategy goes up, we have increasing income. And the older you get, the Yeah, yeah. Well, Alan, I appreciate you coming on to the DoorGrow show and bringing this to light for those listening that are not aware you're doing your purpose of educating. So appreciate that. And to wrap up what final words do you have? And then again, why don't you go and share how people can get in touch with you one more time. Alan Porter (18:31) Okay, well I've got a best-selling book out right now on Amazon. It's called Tax-Free Retirement Solution. Again, Tax-Free, Tax-Free Retirement Solution. Jason Hull (18:38) It's called tax, tax free. Retirement solution, okay. Got it. Alan Porter (18:45) And again, you can call me at 910-551-1046. My email is strategicwealth, the number zero at gmail.com. And you can go to my website, which has a plethora. I've got videos, I've got blogs, I've got everything there. And you can book an appointment there at www.strategicwealthstrategies.com. Jason Hull (18:51) email is strategicwealth0 at gmail.com and you can go to my website which has a cluster. I've got videos, I've got blogs. book an appointment there at www.strategicwellscladagy.com. Awesome. Alan, appreciate you being on the show and thanks for your service. You mentioned your former military. Yeah, I appreciate it. So for those watching, if you've ever felt stuck or stagnant in your property management business, you want to take it to the next level, reach out to us at doorgrow.com. Also be sure to join our free Facebook community, Just for Property Management Business Owners at doorgrowclub.com. Alan Porter (19:13) Well, I appreciate it. Jason Hull (19:31) And if you would like to get the best ideas in property management, join our free newsletter at doorgrow.com slash subscribe. And if you found this even a little bit helpful, don't forget to subscribe and leave us a review. We'd really appreciate it. And until next time, remember the slowest path to growth is to do it alone. So let's grow together. Bye everyone.
Ryan Fahey (pronounced “Foy”) — consultant, speaker, and author of four books helping educators launch and scale as entrepreneurs.Big ideas & highlightsAuthentic > algorithmic: why clear opinions outperform beige, AI-generated content.The “last 20%” of growth: being fully yourself so the right people follow.Teachers → founders: turning buried skills into offers, pricing with confidence.Speaking starter kit: assets to collect before chasing stages.“Add value daily”: the habit that compounds in life and business.Impact beyond the balance sheet—and why sticking around wins the long gameTimestamps / chapters00:00 – Cold open, baseball talk, PEI & Blue Ridge vibes03:55 – Who is Ryan Fahey? Dad, husband, entrepreneur, speaker, author05:40 – Authenticity as the growth unlock (“the last 20%”)07:50 – AI everywhere vs. human voice; why 1 real video beats 100 clones09:25 – “Don't be the mayor of vanilla town”: have an opinion, repel & attract11:45 – Niche & offers: helping educators become entrepreneurs14:45 – Humble pricing, buried skills, and making the leap efficiently16:50 – Should you write the book first? Sequencing brand → book for lift17:55 – Speaking: assets, testimonials, and building your page18:40 – First stage stories and the virtual keynote era21:33 – Listener chain: “What keystone habits make you unstoppable?”22:15 – Impact goals that don't show up on a P&L23:53 – Rodric on service, time studies, and keeping energy-rich workRyan Fahey Quotes:“Don't be the mayor of vanilla town.”“People follow real people. One piece of you beats 100 pieces of fake you.”“If you add value daily, the market will reward you over time.”“Most teachers already have the skills— they're just buried.”“Stick around long enough and you win the long game.”Resources & mentionsRyan's site: faheyconsulting.orgLinkedIn: https://www.linkedin.com/company/fahey-consulting/Instagram: https://www.instagram.com/wellnessrf88/Facebook: https://www.facebook.com/wellnessrfRodric's foundation: Send a Student Leader Abroad (SASLA)EF Tours (context around student travel)Books referenced: Robin SharmaHousekeepingRyan's question for the next guest: “What keystone habits make you unstoppable?”Pronunciation note: Fahey = “Foy.”Resources:Million Dollar Flip FlopsFollow Us on Insta Ready to transform your business and your life while making a difference? Grab your copy of *Million Dollar Flip Flops*—the ultimate guide to creating a life and business that feels just as good as it looks. And here's the best part: 100% of the proceeds go directly to our foundation, Send a Student Leader Abroad, with a goal of sending 1,000,000...
Please visit answersincme.com/CAZ860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in hematology-oncology answers the most commonly asked questions from clinicians about the management of relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) with antibody–drug conjugates (ADCs). Upon completion of this activity, participants should be better able to: Identify patients with R/R DLBCL who may benefit from ADC therapy in the third-line or later setting; Interpret current evidence to inform selection of ADC therapies for patients with R/R DLBCL in the third-line or later setting; and Discuss strategies to optimize the use of ADC therapies for patients with R/R DLBCL, particularly in the community setting.
Text me Your email for my Booking Link“We built this studio by staying intentional with our teaching, our sequencing, and our community — one relationship at a time.” — Sam MegrawIn this episode, I'm joined by Sam Megraw, the co-owner of Easy Tiger Yoga KC, a fast-growing Yoga Studio in Kansas City built on thoughtful sequencing, strong partnerships, and a real commitment to community. Sam shares how she went from teaching to running a thriving two-studio operation — and how listening to this podcast helped shape her founders presale before she even opened.We talk about what actually matters when you're launching or growing a Yoga Studio: great teaching, consistency, simple systems, and serving the people right in front of you.In This Episode We Cover:• Sam's journey from teacher to studio owner• The early days of Easy Tiger Yoga and how they grew quickly• Why intelligent sequencing has become their signature• How Sam and her partner Emily balance strengths to lead the studio• What makes a truly great yoga teacher in 2025– Building community through personal connection, names, and follow-up• How thoughtful onboarding sets students up for long-term success• Why authenticity and patience matter more than hype– Sam's current plans for studio growth and teacher developmentConnect With Easy Tiger Yoga KC:Website: https://www.easytigeryogakc.com Instagram: https://www.instagram.com/easytigeryogakcWork With Michael Jay – Yoga Biz ChampI'm opening December appointments for studio owners who want to start a 6-month Start-A-Studio or Grow-A-Studio coaching package in January.If you want 2026 to feel strategic, supported, and profitable — this is your window.
What if the key to confident, authentic teaching is letting go of rigid rules and stepping into your own way of moving? In this episode, we sit down with Sarah White to explore how creative sequencing can shift not only your classes but your entire relationship with yoga.Part one of this conversation dives into Sarah's journey from Emirates cabin crew to internationally recognised yoga educator, and how she found her way to the intuitive, intention-led method she is now known for.We talk aboutThe moment she realised yoga was her callingHow rigid sequencing left her burnt out and why simplicity became her anchorWhy creative sequencing is not about fancy transitions but about depth, agency and embodimentThe four part structure at the heart of her approach and why she reverse engineers every flowThe teachers who gave her permission to break the rules and trust her intuitionHow nature, curiosity and small movements spark her creativity and shape the themes she teachesSarah opens up about the values that guide her work, the freedom she wants for every teacher and the moment she realised sequencing could feel alive rather than restrictive.Part two continues the conversation and goes even deeper into intuition, planning and the realities of building a yoga business.Listen now and get ready to rethink what a yoga class can be.About SarahSarah White is a UK-born, internationally recognised yoga educator and the creator of the signature training Creative Sequencing. With over seven years of full-time teaching experience, she has guided teachers across the globe to move beyond rigid sequencing rules and into a more embodied, intentional, and confident approach to their classes. Having spent 12 years establishing her career in Dubai, Sarah recently relocated to Kentucky, where she continues to share her work with an international audience. Known for blending creativity with depth and practicality, she's passionate about helping yoga teachers find their unique voice and bring it to life on the mat.Visit Sarah's website hereFollow Sarah on InstagramAbout Alba Yoga AcademyLearn more with Alba Yoga AcademyLearn more about our Yoga Teacher Training here.Watch our extensive library of YouTube videos.Follow Hannah on Instagram.Follow Celest on Instagram
Tired of the spike-and-crash? Everyday staples—cereal, rice, potatoes, even tropical fruit—can surgeblood sugar unless you change the order and the partners. Learn fiber-first sequencing and simplepairings that tame spikes, boost satiety, and protect metabolic health—without losing flavor.Special Guest: Jim LaValle, Clinical Pharmacist discussing Kyolic Aged Garlic Extract
John Oakley hosts an extraordinary conversation with geneticist and archaeologist Dr. Turi King, who breaks down the science behind the recent genome sequencing of Adolf Hitler using a bloodstained relic from his Berlin bunker. From medical anomalies like Kallmann syndrome to the ethical limits of DNA in psychological profiling, King separates fact from speculation. The show also explores Toronto's performative civic acknowledgements—slavery, land, and beyond—with guests David Wills, VP at Media Profile, and National Post columnist Tristan Hopper, who challenges the rise of revisionist narratives in public ceremonies. A compelling mix of science, history, politics, and public discourse. Learn more about your ad choices. Visit megaphone.fm/adchoices
Is the most important part of plastic surgery the scalpel—or the psychology behind why you choose it and how you feel afterward?In this candid episode of Plastic Surgery Uncensored, I sit down with my longtime patient-turned-friend, Alexis, to unpack her 15-year journey—four surgeries, eight procedures—and the mindset shifts behind each decision. From a post-pregnancy mommy makeover (tummy tuck with diastasis repair) to a breast lift with implants, then subtle upper-face rejuvenation (limited lateral brow lift + upper lids), and finally a lower-face/neck transformation (deep-plane facelift + small chin implant + lower lids + micro-fat grafting), we show how sequencing, restraint, and honesty can deliver results that look fresh—not “done.” We talk openly about why some patients stay secretive, why others are proudly transparent, and how to navigate judgment, social media distortion, and the myth that more procedures = a “cat face.” You'll also hear how motherhood, weight changes, and aging shift priorities—and why sometimes the kindest thing you can do for your family is to put your own “oxygen mask” on first.In this episode, you'll learn:The right procedure at the right time: why exercise can't fix loose skin or diastasis, and when surgery is the missing puzzle piece.Sequencing that makes sense: convenience, recovery, and why breasts + abdomen often play better together.Face vs. filler: when fillers help—and when a facelift/necklift is the “screwdriver,” not the hammer.Chin implant reality check: tiny, customized implants that sharpen a jawline without changing who you are.Natural, not noticeable: how subtle technique (and using less pull, not more) avoids the “weird” look.Mindset matters: dropping shame, embracing empowerment, and being honest for the sake of others' expectations.Who this episode is for: those considering a mommy makeover, anyone debating face/neck rejuvenation in their 40s–50s, and listeners confused by the internet's extremes who just want practical, compassionate guidance.If this helped you, pay it forward:Leave a kind review (it means the world to our team), and share the episode with anyone you love who's thinking about plastic surgery—before they book, so they can make informed choices. — Dr. Rady Rahban, Plastic Surgery Uncensored✨ If you enjoyed this episode of Plastic Surgery Uncensored:✔️ Subscribe on Apple Podcasts, Spotify, or wherever you listen.✔️ Rate & Review—your feedback helps more people find us.✔️ Follow Dr. Rady Rahban across all platforms for daily insights, behind-the-scenes, and patient education:Instagram: @drradyrahbanTikTok: @radyrahbanMDYouTube: @Rady RahbanFacebook: @Rady Rahban✔️ Share this episode with someone considering plastic surgery—the right knowledge can save a life.
When everyone can generate AI content, taste and storytelling are the new performance metrics. In this week's episode of Growth Talks, Everett Butler, Head of Marketing at Lindy, joins host Krystina Rubino to unpack what it takes to bring a brand-new product category to market when there is no roadmap, no search volume, and no shared language. With over fifteen years of experience scaling teams at Tesla, Uber, and Affirm, Everett shares how to apply first principles thinking to build a go-to-market strategy grounded in fundamentals, aligned with real customer needs, and focused on clarity over complexity. Tune in to learn the key traits Everett looks for in modern AI marketers — and why taste, product-led storytelling, and genuine curiosity are more valuable than ever.
This week on Songs That Don't Suck, Mark dives into the lost art of mixtapes, what made them magical, and contrasts them with today's algorithm-driven playlists. Plus, four killer tracks from Robert Delong, Tors with Jade Bird, Black Orchid Empire, and Howl Owl Howl.To check out this week's songs on your platform of choice head to the website Songs That Don't SuckConnect with Songs That Don't Suck ~ Instagram | BlueSky
Today's guest is Lynette Byerly, BSN, RN, CCDS, CCS, a clinical documentation education specialist with HCPro and ACDIS. Today's show is hosted by ACDIS Director Rebecca Hendren, and features a special ACDIS update with members of the ACDIS team. Our intro and outro music for the ACDIS Podcast is “medianoche” by Dee Yan-Kay and our ad music is “Take Me Higher” by Jahzzar, both obtained from the Free Music Archive. Have questions about today's show or ideas for a future episode? Contact the ACDIS team at info@acdis.org. Want to submit a question for a future "listener questions" episode? Fill out this brief form! CEU info: Each ACDIS Podcast episode offers 0.5 ACDIS CEU which can be used toward recertifying your CCDS or CCDS-O credential for those who listen to the show in the first four days from the time of publication. To receive your 0.5 CEU, go to the show page on acdis.org, by clicking on the “ACDIS Podcast” link located under the “Free Resources” tab. To take the evaluation, click the most recent episode from the list on the podcast homepage, view the podcast recording at the bottom of that show page, and click the live link at the very end after the music has ended. Your certificate will be automatically emailed to you upon submitting the brief evaluation. (Note: If you are listening via a podcast app, click this link to go directly to the show page on acdis.org: https://acdis.org/acdis-podcast/problem-list-sequencing) Note: To ensure your certificate reaches you and does not get trapped in your organization's spam filters, please use a personal email address when completing the CEU evaluation form. The cut-off for today's episode CEU is Sunday, November 9, at 11:00 p.m. Eastern. After that point, the CEU period will close, and you will not be eligible for the 0.5 CEU for this week's episode. ACDIS update: Check out the 2026 ACDIS conference agenda and register today! (http://bit.ly/3W5ir8Y) Submit your poster presentation proposal for the 2026 ACDIS conference by December 12! (https://www.surveymonkey.com/r/26poster) Submit your 2026 ACDIS Achievement Award nominations by December 12! (https://www.surveymonkey.com/r/26award) Apply for a 2025/2026 ACDIS CDI Scholarship Award by November 23! (https://www.surveymonkey.com/r/ACDISscholarship2025) Read the November/December 2025 edition of the CDI Journal now! (http://bit.ly/4nwVffg) Submit your articles for the January/February 2026 edition of the CDI Journal by December 1! (https://www.surveymonkey.com/r/CDI-journal)
Featuring an interview with Prof Patrick Neven, including the following topics: Emergence of ESR1 mutations in ER-positive, HER2-negative breast cancer (0:00) Observed toxicity profile of oral selective estrogen receptor degraders (SERDs) (3:57) Emerging data with novel oral SERD combinations (6:31) Challenges for a general medical oncologist in breast cancer (8:41) Sequencing and selection of therapies in ER-positive, HER2-negative breast cancer (12:16) Evaluating the strategy of switching to an oral SERD during first-line endocrine therapy upon "molecular progression" (23:16) CME information and select publications
Dr. Sarah Camargos interviews Dr. Guillaume Cogan and Prof. Alexis Brice, the corresponding authors of the article selected as the Movement Disorders Review of the Year. Listen as their conversation dives into the new sequencing technologies, and the broader diagnosis they bring to the field.
Guest: Joel Gabre, M.D, MPH On this episode of Advances in Care, host Erin Welsh and Dr. Joel Gabre, a gastroenterologist at NewYork-Presbyterian and Columbia who specializes in cancer care, discuss the ongoing rise in colorectal cancer rates among younger individuals. Dr. Gabre lays out trends observed by the medical community in colorectal cancer rates, including the increasing likelihood by birth cohort for patients to develop this disease. He also talks about the main differences in colorectal cancer for patients from these different cohorts, most notably the location where cancers are likely to develop in the colon. In addition, Dr. Gabre shares some of the leading hypotheses for why colon cancer rates are rising in younger people, and how clinicians and researchers are focused on searching for answers to improve prevention and treatment options. He gets into the importance of the western diet in developing these forms of cancer and shares details about his team's recent findings regarding changes at the cellular level that could be contributing to the accelerated growth of these cancers. Finally, Dr. Gabre speaks to his personal experiences as a gastroenterologist who has seen first-hand the rise in colon cancer rates among his younger patients. He shares a story of what …
Milo Lines is a PGA Professional, a Golf Digest "Best Teacher in State," and a former Tour Professional. His philosophy on the golf swing is that there is crossover, especially in sports involving hitting and throwing, with golf and the golf swing. As a teacher his goal is to apply the athletic skills you already have and teach you the skills you need in order to improve as a golfer. He joins #OntheMark to help you apply your athletic instinct and experiences to make your golf swing more athletic and effective. Milo shares his "5 Key Elements" to an athletic approach to the golf swing: ALIGNING - Grip, Aim and Alignment SEQUENCING - Swing Triggers, Timing, Rhythm and Tempo WINDING - Turning and Tilting athletically LOADING - The Athletic approach to the Transition and Change of Direction UNLEASHING - The Automatic Release of the club thanks to proper Sequencing, Winding and Loading. Milo also illustrates PGA TOUR examples such as Lee Trevino and Jack Nicklaus as athletic swing models, and teaches you a Drill (Laddering) that will improve your practice and unleash your inner athlete. This podcast is also available as a vodcast on YouTube. Search and subscribe to Mark Immelman.
In this episode, Loral Langemeier joins John Casmon to share her most powerful wealth building strategies and lessons from a remarkable career that began on a Nebraska farm and led to becoming “The Millionaire Maker.” From working with Bob Proctor and the Rich Dad Poor Dad team to authoring six bestselling books, Loral explains how mentorship, sequencing, and mindset create sustainable wealth.Through real stories, she breaks down the myths that keep people stuck, including the false belief that you must be debt-free before you can grow. Instead, she explains why doing the right thing at the right time and surrounding yourself with the right mentors can fast-track results.Whether you're transitioning from a 9-to-5, investing in real estate, or starting your first business, this conversation is packed with actionable wealth building strategies that help you think, act, and build like a millionaire.Loral's Takeaways:Loral Langemeier's Background and Early Career (00:00)Transition to Real Estate and Becoming a Millionaire Maker (02:39)The Importance of Mentorship and Team Building (11:06)Sequencing and Financial Strategy (17:35)Overcoming Challenges and Achieving Success (30:27)Connect with John Casmon:https://casmoncapital.com/https://www.linkedin.com/in/multifamily-apartments-john-casmon/https://www.instagram.com/jcasmon/?hl=enMeet Loral Langemeier:Loral Langemeier is a money expert, sought-after speaker, entrepreneurial thought leader, and best-selling author of five books.Her goal: to change the conversations people have about money worldwide and empower people to become millionaires.The CEO and Founder of Live Out Loud, Inc. – a multinational organization — Loral relentlessly and candidly shares her best advice without hesitation or apology. What sets her apart from other wealth experts is her innate ability to recognize and acknowledge the skills & talents of people, inspiring them to generate wealth.She has created, nurtured, and perfected a 3-5 year strategy to make millions for the “Average Jill and Joe.” To date, she and her team have served thousands of individuals worldwide and created hundreds of millionaires through wealth-building education keynotes, workshops, products, events, programs, and coaching services.Loral is truly dedicated to helping men and women, from all walks of life, to become millionaires AND be able to enjoy time with their families.She is living proof that anyone can have the life of their dreams through hard work, persistence, and getting things done in the face of opposition. As a single mother of two children, she is redefining the possibility for women to have it all and raise their children in an entrepreneurial and financially literate environment. Links and Resources:Ask Loral App: https://apple.co/3eIgGcXLoral on Facebook: https://www.facebook.com/askloral/Loral on YouTube: https://www.youtube.com/user/lorallive/videosLoral on LinkedIn:
New FDA-approved therapies for BCG-refractory non-muscle invasive bladder cancer (NMIBC)–where do they fit in the treatment algorithm, and how do you administer them? This installment of the 2025 NMIBC Creator Weekend™ series features host Dr. Bogdana Schmidt, assistant professor of Urologic Oncology at the University of Utah, and leading urologic oncologists Dr. Mark Tyson from Mayo Clinic Arizona and Dr. Suzanne Merrill from Colorado Urology.---This podcast is supported by:Ferring Pharmaceuticalshttps://www.ferring.com/home-classic/people-and-families/uro-uro-oncology/bladder-cancer/---SYNPOSISThe discussion delves into the newest treatment strategies and FDA-approved therapies for non-muscle invasive bladder cancer with an emphasis on BCG-refractory patients. They highlight their approaches to sequencing therapies, the real-world applicability of these treatments, and the impact of patient factors in clinical decision-making. The panel also explores emerging trials and innovative treatment mechanisms, emphasizing the importance of personalized care in oncology.---TIMESTAMPS00:00 - Introduction05:09 - Challenges and Strategies in Treatment10:55 - Bladder Sparing Therapies21:41 - Practical Tips for Therapy Administration30:39 - Challenges and Considerations in Reinduction37:05 - Clinical Trials and Future Directions44:11 - Counseling Patients on Treatment Options57:36 - Concluding Thoughts and Future Outlook---RESOURCESCORE-008 Clinical Trial https://www.sciencedirect.com/science/article/abs/pii/S1078143924010147Legend Clinical Trial:https://ascopubs.org/doi/10.1200/JCO.2025.43.5_suppl.802CISTO Studyhttps://pubmed.ncbi.nlm.nih.gov/37980511/
This week -- a solocast from Jason, fresh from his trip teaching a weeklong "Sequencing 2.0" training in London. On this episode, he breaks down a practical framework for scaling a single 60-minute sequence into:(1) shorter online formats(2) longer workshops(3) four-week series with clear objectivesHe also explains why real creativity comes from solving for a goal—not from random choreography—and how to communicate a simple plan so students feel part of something bigger. Psst! Don't miss next week's episode where we launch a four-part “Transformation Series,” that follows three of Jason's trainees through their teacher training journey. Hosted on Acast. See acast.com/privacy for more information.
What if the problem isn't your concrete, but how you run your business? In this episode of the Concrete Logic Podcast, Seth Tandett talks with Tamson Omps, Director of Operations at Thomas Concrete, about how ready-mix producers can finally take control of their margins. Tamson lays out the seven areas that make or break profitability in the ready-mix business—from equipment maintenance and driver retention to scheduling and waste management. Whether you manage a single plant or oversee a regional operation, this episode gives you a practical, no-nonsense look at what's actually driving your profits (and losses) today. What You'll Learn • Why does Tamson say “we don't sell concrete—we sell truck space”? • What simple maintenance strategy can save thousands in downtime? • How can ready-mix companies cut driver turnover by focusing on the right incentives? • What's the real cost of a truck sitting on the jobsite? • How does batching setup and admixture sequencing impact load times and profit? • What can schedulers do to eliminate wasted hours in the yard? • How can waste and return concrete be turned into an extra revenue stream? Chapters 00:00 – Introduction: The Profitability Puzzle in Ready-Mix 01:19 – Shifting Perspective: Concrete as a Service, Not a Product 03:25 – Low Hanging Fruit: Equipment Maintenance 04:36 – People Matter: Keeping Delivery Pros on the Team 08:20 – Truck Turnaround: The Real KPI That Matters 11:02 – Load Times and Plant Flow: Admixtures, Sequencing, and Efficiency 18:16 – Scheduling for Success: Managing Peak Demand 22:54 – Waste Management: Turning Returns into Revenue Guest Info Tamson Omps Director of Operations, Thomas Concrete Email: tamson.omps@thomasconcrete.com LinkedIn: https://www.linkedin.com/in/tamson-omps-mba/ Company: Thomas Concrete – https://www.thomasconcrete.com Concrete Logic Academy Earn PDHs the easy way. Listen to podcast episodes, complete a short quiz, and get professional development hours with proper documentation. Start your free trial: https://www.concretelogicacademy.com Support the Podcast This show runs on a Value-for-Value model. If you got value from this episode, consider supporting us: https://www.concretelogicpodcast.com/donate Support the show while gearing up with KUIU premium outdoor gear—what Seth wears both on the hunt and on the job. Shop through this link at no extra cost: https://www.concretelogicpodcast.com/KUIU Want help with media services like podcasting or YouTube for your concrete company? Reach out to Seth at seth@concretelogicpodcast.com. Credits Producers: Jodi Tandett and Concrete Logic Media Music by Mike Dunton – https://www.mdunton.com Connectivity Host: Seth Tandett – Concrete Visionary & Business Development Manager at Baker Construction LinkedIn: https://www.linkedin.com/in/sethtandett YouTube: https://www.youtube.com/@concretelogicpodcast Website: https://www.concretelogicpodcast.com Don't forget to like, subscribe, comment, and share. Let's keep it concrete.
The Perfect Stool Understanding and Healing the Gut Microbiome
Ever wondered if your gut health protocols are truly helping, or possibly harming, your microbiome? Join Lindsey Parsons and Dr. Brad Leech as they unpack the latest science on antimicrobials, microbiome testing, leaky gut, low stomach acid, prebiotics and more. Discover when to use certain interventions, how to protect your beneficial bacteria, and which strategies really make a difference based on the research. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, X, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes
Featuring a slide presentation and related discussion from Dr Laura Huppert, including the following topics: Overview of approved antibody-drug conjugates (ADCs) for metastatic hormone receptor-positive HER2-negative breast cancer — trastuzumab deruxtecan, sacituzumab govitecan and datopotamab deruxtecan(0:00) Approved and investigational ADCs for metastatic triple-negative breast cancer (17:18) Sequencing of ADCs for metastatic HER2-negative breast cancer; future research directions (26:10) CME information and select publications
In this episode of Executive Health & Life, host Julian Hayes II sits down with Dr. Jason Sonners, a leading expert in Hyperbaric Oxygen Therapy (HBOT), to explore how this cutting-edge modality can help executives, entrepreneurs, and high performers improve their recovery, mental clarity, and longevity.Dr. Sonners explains the science behind HBOT, how it supports cellular repair and mitochondrial functioning, and why it's fast becoming a go-to strategy for business leaders who want to extend their peak years. You'll learn how to use oxygen therapy for energy, focus, inflammation control, and overall resilience.— Episode Chapter Big Ideas (timing may not be exact) —0:00 – Welcome & why health freedom drew Dr. Sonners to Miami05:45 – How a PhD in molecular biology deepened his work in regenerative medicine09:40 – What Hyperbaric Oxygen Therapy actually is, and what it's not14:30 – The back injury that led Dr. Sonners to discover HBOT20:45 – The science: oxygen pressure, healing, and energy production25:10 – HBOT for longevity: inflammation, mitochondria, and aging31:00 – How often to use HBOT and how to structure your sessions35:20 – Oxygen toxicity myths and how to choose a certified clinic40:10 – Stacking HBOT with red light, methylene blue, NAD, and cold exposure46:30 – Sequencing your recovery and performance plan49:30 – HBOT's link to gene expression and biological aging55:00 – Miami's rise as a wellness capital1:00:00 – Final reflections on patience, consistency, and sovereignty in health— Key Quotes from Dr. Jason Sonners — “Oxygen isn't the treatment—it's the ingredient. Hyperbaric oxygen therapy simply gives your body what it needs to heal itself.”“Your body already knows how to recover. HBOT just removes the barriers that keep it from doing what it's designed to do.”— Connect With Dr. Jason Sonners —Website: https://hbotusa.com/ Instagram: https://www.instagram.com/hbotusa/ YouTube: https://www.youtube.com/@HBOTUSA Book - Oxygen Under Pressure: https://www.amazon.com/Oxygen-Under-Pressure-Inflammation-Revolutionize/dp/1661251358/ — Connect with Julian and Executive Health —LinkedIn — https://www.linkedin.com/in/julianhayesii/Ready to take your health, leadership, and performance to the next level? Book a complimentary private executive health diagnostic call with Julian Hayes II. Link below. https://calendly.com/julian-exechealth/chemistryWebsite — https://www.executivehealth.io/***DISCLAIMER: The information shared is not meant to treat or diagnose any condition. This is for educational, informational, and entertainment purposes. The content here is not intended to replace your relationship with your doctor and/or medical practitioner.
When every board discussion centers on deficits, deferred maintenance, or another “strategic realignment,” higher education leaders start asking what it would take to fix the system instead of just managing decline. In this episode of the Changing Higher Ed® podcast, Dr. Drumm McNaughton speaks with Beth Martin, President of Notre Dame de Namur University (NDNU), who led her institution through a complete financial and operational turnaround—eliminating institutional debt through strategic real estate use, risk planning, and sound financial governance. Martin's experience offers a rare look at what it takes to execute a true higher education turnaround. She shares how NDNU's leadership aligned governance, mission, and financial strategy to not only survive but rebuild a sustainable model focused on graduate and online growth. This conversation is especially relevant for presidents, trustees, CFOs, and institutional leaders facing financial strain, considering asset monetization, or preparing for large-scale organizational change. Topics Covered: How NDNU executed a debt-free turnaround through real estate strategy and risk planning Applying business planning and systems theory to higher education transformation Managing institutional debt while investing in academic and technological infrastructure Governance structures that enable speed, trust, and accountability during turnaround Aligning presidents, boards, and sponsoring orders in complex financial transactions Leading cultural and organizational change while maintaining mission and morale Real-World Examples Discussed: NDNU's 46-acre land transaction that retired institutional debt and funded new programs Sequencing real estate sales to support strategy instead of short-term survival Governance reform guided by a skills matrix and board-chair alignment Realigning academic programs around graduate and online learning Faculty and staff engagement during institutional transition Three Key Takeaways for Leadership: Treat land monetization as strategy, not salvage. Link every major financial decision to a defined business plan and measurable outcomes. Integrate business and risk planning into every turnaround. Build contingencies for timing, regulation, and accreditation challenges. Strengthen governance alignment. A unified president and board chair, supported by a skills-based board, determine turnaround success. Read the transcript: https://changinghighered.com/debt-free-higher-education-turnaround-strategy-real-estate/ #HigherEdLeadership #HigherEdTurnaround #HigherEducationPodcast
In today's episode, we had the pleasure of speaking with Kanwal P. S. Raghav, MBBS, MD, about the role of fruquintinib (Fruzaqla) in the treatment of adult patients with pretreated, metastatic colorectal cancer (CRC). Dr Raghav is a professor in the Department of Gastrointestinal Medical Oncology in the Division of Cancer Medicine, associate vice president of the Department of Ambulatory Medical Operations, and executive medical director of the Department of Ambulatory Treatment Centers at The University of Texas MD Anderson Cancer Center in Houston. In our exclusive interview, Dr Raghav discussed the mechanism of action of fruquintinib, key efficacy data from the phase 3 FRESCO (NCT02314819) and FRESCO-2 (NCT04322539) trials, the treatment settings where this agent is most frequently administered, and adverse effects to be aware of. He also noted how the role of fruquintinib in earlier lines of therapy has yet to be defined due to a lack of optimal predictive biomarkers. Dr Raghav concluded by emphasizing the importance of clinical trials for improving outcomes for patient with CRC.
This week Joe is solo and he's answering 4 of YOUR questions! Specific topics include: 1) Is eccentric duration important for muscle hypertrophy? (If not, is there EVER a reason to intentionally slow down the eccentric portion of the lift?) 2) What NOT to do [training-wise] if you're looking to build muscle and strength 3) Are glucose monitors beneficial for non-diabetics? Should we be concerned about "insulin spikes" when trying to drop body fat? 4) The best way to sequence exercises for joint health (on a PPL split)...And MORE! *For a full list of Show Notes + Timestamps visit www.IndustrialStrengthShow.com IMPORTANT LINKS DeFranco's Nutritional Supplements Team Forever Strong [FREE Trial] Joe's most viral IG post Pain-Free Dip technique
This week Joe is solo and he's answering 4 of YOUR questions! Specific topics include: 1) Is eccentric duration important for muscle hypertrophy? (If not, is there EVER a reason to intentionally slow down the eccentric portion of the lift?) 2) What NOT to do [training-wise] if you're looking to build muscle and strength 3) Are glucose monitors beneficial for non-diabetics? Should we be concerned about "insulin spikes" when trying to drop body fat? 4) The best way to sequence exercises for joint health (on a PPL split)...And MORE! *For a full list of Show Notes + Timestamps visit www.IndustrialStrengthShow.com IMPORTANT LINKS DeFranco's Nutritional Supplements Team Forever Strong [FREE Trial] Joe's most viral IG post Pain-Free Dip technique
We dropped a stat this week that stopped Nate in his tracks: brands can see up to 42% more sales just by framing discounts the right way. No new ads, no extra products...just choosing percent off vs. dollar off at the right moment. In Episode 105, we dig into the psychology behind that lift and why most brands blow Q4 by overcomplicating offers, stacking promos, and teaching customers not to trust them. Inside the conversation: ✅ The science behind when to use % off vs. $ off (and why it changes sitewide vs. single product) ✅ The 5 offer types we see every year — and which ones are worth your testing budget ✅ Why “combo deals” and “sale extended” emails wreck trust long-term ✅ Sequencing tactics (like Nate's “Better Than Black Friday” play) that build urgency without burning credibility ✅ Why sometimes the boldest Q4 strategy is raising prices, not cutting them If you've ever wondered: 1. How to simplify offers so customers don't need a calculator 2. Why half-off deals aren't always the flex you think they are 3. How to build trust during the most profitable month of the year 4. And why less discounting can actually mean more margin …this one's for you. Season 3 keeps pushing, and the data's spicy.
In this podcast, Josh Malerman talks about his brand new book, Watching Evil Dead, unearthing the radiant artist within, sequencing book order like an album, and much more. About Josh Malerman Josh Malerman is an American novelist, short story writer, film producer, and one of two singer/songwriters for the rock band The High Strung. He … Continue reading
Dr. Tomi Pastinen, director of Genomic Answers for Kids, led the first clinical study of five-base long read sequencing, recently published in the Journal of the American Medical Association Pediatrics. This new method shows doctors more of the genome and can diagnose rare diseases with a single test.
In this episode, Sara Tolaney, MD, of Dana-Farber Cancer Institute, discusses sequencing strategies after progression in...
In this episode, Sara Tolaney, MD, of Dana-Farber Cancer Institute, discusses sequencing strategies after progression in HER2-positive metastatic breast cancer. She reviews current second-line standards, considerations for patients with brain metastases, and emerging therapies in the post–T-DXd setting.Let us know what you thought of this week's episode on Twitter: @physicianswkly Want to share your medical expertise, research, or unique experience in medicine on the PW podcast? Email us at editorial@physweekly.com! Thanks for listening!
In this episode, Cressey Sports Performance - Florida pitching coach Spencer Stockton covers a wide variety of topics. Spencer reflects on the training and mechanical cues that benefited him the most as a hypermobile pitcher. Taking it a step further, he digs in on the power of motion capture technology, and coaching with a combination of data and "feel."Support Our Sponsor: AG1
Featuring an interview with Dr Beth Faiman, including the following topics: Clinical practice background and historical view of treatment for multiple myeloma (MM) (0:00) Fundamental principles associated with chimeric antigen receptor (CAR) T-cell therapy (7:19) Sequencing of CAR T-cell therapy and bispecific antibodies in the MM treatment landscape (9:00) Patient eligibility to receive CAR T-cell therapy (13:23) Differentiating among approved CAR T-cell therapies for MM (18:18) Durability of responses to CAR T-cell therapy for MM (24:01) Neurotoxicity with CAR T-cell therapies for MM (26:26) Minimal residual disease monitoring in MM (29:39) Support systems for the management of toxicities associated with CAR T-cell therapy (35:10) Patients with MM experiencing durable responses to CAR T-cell therapy (43:11) NCPD information and select publications
Dr Ana C Garrido-Castro and Prof Peter Schmid review patient cases and provide insights regarding the treatment of metastatic triple-negative breast cancer. CME information and select publications here.
Featuring perspectives from Dr Ana C Garrido-Castro and Prof Peter Schmid, including the following topics: Introduction: Legendary Figures in Breast Cancer Research (0:00) Case: A woman in her early 80s, a current smoker with a history of myocardial infarction and stroke, who develops recurrent triple-negative breast cancer (TNBC) — Justin Favaro, MD, PhD (6:44) Case: A woman in her late 60s with metastatic TNBC and a PD-L1 level of 20% who receives chemotherapy/pembrolizumab followed by sacituzumab govitecan — Priya Rudolph, MD, PhD (25:08) Case: A woman in her late 60s with localized TNBC who develops myocarditis while receiving neoadjuvant chemotherapy/pembrolizumab — Richard Zelkowitz, MD (33:53) Case: A woman in her mid 60s with recurrent ER-negative, HER2-low, PI3K-mutant TNBC — Ranju Gupta, MD (37:49) Case: A woman in her early 60s with recurrent TNBC confined to contralateral neck nodes — Eric H Lee, MD, PhD (42:10) Case: A woman in her early 40s with metastatic TNBC who receives sacituzumab govitecan after multiple lines of chemotherapy — Estelamari Rodriguez, MD, MPH (48:10) Case: A woman in her mid 70s with ER-negative, HER2-low breast cancer who develops an isolated brain metastasis — Dr Gupta (55:02) CME information and select publications
Standards for simulated patient encounters have been developed; however, the sequencing of simulation experiences has not been well-established. Sequencing purposefully manipulates the order of nursing content delivery including didactic, simulation, and clinical practice. Limited research has prevented the development of sequencing standards that may improve student learning. Learn more about simulation sequencing in this podcast with Brandy Falconer and the few studies that have been done.
In this episode of The SHEA Podcast, Dr. Katie Chiotos (Children's Hospital of Philadelphia) and Dr. Trevor Van Schooneveld (University of Nebraska Medical Center) discuss the stewardship of metagenomic sequencing (mNGS) in infectious disease care. They explore how to make results clinically actionable, avoid overuse or misinterpretation, and integrate mNGS into stewardship and infection prevention programs. The conversation also looks ahead to the future of mNGS and the role stewardship leaders will play in guiding its responsible use.
Join us for an insightful episode as we dive deep into the evolving landscape of Chronic Lymphocytic Leukemia (CLL) treatment. This episode features Dr. Mazyar Shadman, an expert in lymphoid malignancies from the Fred Hutch Cancer Center. In this episode, we covered: • The importance of shared decision-making in CLL treatment. • When to initiate treatment for newly diagnosed CLL patients. • The role of time-limited venetoclax-based regimens versus continuous BTK inhibitors. • Key considerations in choosing the right BTK inhibitor and managing side effects. • The relevance of minimal residual disease (MRD) in treatment duration. • Sequencing strategies for relapsed and refractory CLL, including the use of Pirtobrutinib and CAR-T therapy. Whether you're a healthcare professional or someone interested in the latest advancements in oncology, this episode is packed with valuable insights and practical advice. Don't forget to like, subscribe, and leave us your feedback! Your support helps us bring these important discussions to a wider audience. Tune in now and stay informed about the latest in CLL treatment! Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ #Ibrutinib #acalabrutinib #zanubrutinib #Pirtobrutinib #CLL2025 #BTKinhibitors #Venetoclax #MRDnegative #OncologyBrothers
Mark A. Stein, Ph.D., will provide an overview of pediatric ADHD treatment options, explain why it's crucial to personalize treatment, and how to combine and sequence medication and other treatments for optimal care. ADHD Treatments for Children: Additional Resources Free Download: Take Charge of Your Child's Medication Read: ADHD Treatment Options for Children Read: What Is Complex ADHD? Symptoms, Diagnosis & Treatment Read: How a Physician Treats ADHD with Combination Therapy Access the video and slides for podcast episode #571 here: https://www.additudemag.com/webinar/adhd-treatment-options-combination-therapy/ This episode is sponsored by the podcast Hyperfocus with Rae Jacobson. Search for “Hyperfocus with Rae Jacobson” in your podcast app or find links to listen at https://lnk.to/hyperfocusPS!adhdexperts. This episode is also brought to you by Brain.fm. Unlock your brain's full potential FREE for 30 days by going to brain.fm/ADDITUDE. Thank you for listening to ADDitude's ADHD Experts podcast. Please consider subscribing to the magazine (additu.de/subscribe) to support our mission of providing ADHD education and support.
Featuring an interview with Dr Erika Hamilton, including the following topics: Monitoring, mitigating and managing adverse events with antibody-drug conjugates (ADCs) for breast cancer (0:00) Heist RS et al. Clinical management, monitoring, and prophylaxis of adverse events of special interest associated with datopotamab deruxtecan. Cancer Treat Rev 2024;125:102720. Abstract Management protocols for adverse events associated with sacituzumab govitecan (7:49) García JMP et al. Prevention of sacituzumab govitecan (SG)-related neutropenia and diarrhea in patients with triple-negative or HR+/HER2- advanced breast cancer (ABC; PRIMED): A phase 2 trial. ASCO 2024;Abstract 1101. Pérez-García JM et al. Prevention of sacituzumab govitecan-related neutropenia and diarrhea in patients with HER2-negative advanced breast cancer (PRIMED): An open-label, single-arm, phase 2 trial. eClinicalMedicine 2025;85:103309. Abstract Datopotamab deruxtecan for patients with breast cancer brain metastases or leptomeningeal disease (10:51) Tarantino P et al. DATO-Base: A phase II study of DATOpotamab deruxtecan for patients with breast cancer brain metastases or leptomeningeal disease. ASCO 2025;Abstract TPS1134. Sequencing ADCs in breast cancer (13:12) Pacholczak-Madej R et al. Sequencing of antibody drug conjugates in breast cancer: Evidence gap and future directions. Biochim Biophys Acta Rev Cancer 2025;[Online ahead of print]. Abstract CME information and select publications
In this juicy bonus Q&A episode, we kick things off with banter about East Coast Italian-American pride, Bradshaw's first Italian adventure, and our surprising discovery of supri- Rhode Island's beloved cured pork specialty. Then we dive into listener questions: the nitty-gritty of sequencing requirements and what to do when a distracting moaner in class sparks complaints. We explore how sequencing rules can feel limiting but also inspire creativity, and how one moaner story sends Giana spiraling into a tangent about a farter—navigating complaints, boundaries, and those unavoidable uncomfortable conversations.SEND YOUR QUESTIONS TO: CAYAYOGASCHOOL@GMAIL.COM