POPULARITY
12 episodes with cell fate
8 episodes with cell fate
6 episodes with cell fate
6 episodes with cell fate
8 episodes with cell fate
3 episodes with cell fate
4 episodes with cell fate
3 episodes with cell fate
4 episodes with cell fate
Jonathan Weitzman, professor of genetics at the Université Paris Cité in France, joins Jonathan Sackier to discuss the role of epigenetic events in cellular differentiation programmes, as well as his own podcast, ‘The Lonely Pipette'. Use the following timestamps to navigate this episode: (00:00)-Introduction (02:49)-Specialising in epigenetics (05:45)-Helping young scientists navigate their careers (11:58)-Back to basics: epigenetics (19:21)-The emergence of ‘form' (22:02)-Cell reprogramming (23:26)-The Centre for Epigenetics and Cell Fate (24:28)-Genetics in 30 seconds (29:30)-Intracellular hijackers (35:45)-Who am I? (41:20)-Jonathan's three wishes
References Guerra, DJ. 2024. unpublished writings. Seminars in Cell & Developmental Biology2020. 99:86-95 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
Mol Cell Biol. 2012 Jan;32(1):126-38 Mutat Res. 2013 Jul-Sep;753(1):24-40 Molecular Neurobiology 2022. volume 59, pages 4223–4241 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
References Pisendel Johann G. 1735. Violin Concerto in D major Jun P I.7 https://youtu.be/dvwhXXvFiNg?si=BUb-f5rBncgADinx Curr Opin Pharmacol. 2021 Apr; 57: 107–116 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
Toshihiro Kobayashi, Ph.D., presents his research on the mechanisms driving cell fate choices in early mammalian embryos. He also discusses the potential application of these principles in future regenerative medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38328]
Toshihiro Kobayashi, Ph.D., presents his research on the mechanisms driving cell fate choices in early mammalian embryos. He also discusses the potential application of these principles in future regenerative medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38328]
Toshihiro Kobayashi, Ph.D., presents his research on the mechanisms driving cell fate choices in early mammalian embryos. He also discusses the potential application of these principles in future regenerative medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38328]
Toshihiro Kobayashi, Ph.D., presents his research on the mechanisms driving cell fate choices in early mammalian embryos. He also discusses the potential application of these principles in future regenerative medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38328]
Toshihiro Kobayashi, Ph.D., presents his research on the mechanisms driving cell fate choices in early mammalian embryos. He also discusses the potential application of these principles in future regenerative medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38328]
Toshihiro Kobayashi, Ph.D., presents his research on the mechanisms driving cell fate choices in early mammalian embryos. He also discusses the potential application of these principles in future regenerative medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38328]
References Cell. 2020 Jul 23; 182(2):404–416.e14. Nature Communications 2020. volume 11,3146 Curr Genet. 2021 Feb; 67(1):19–26 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
References Scientific Reports 2015.volume 5,Article number: 15292 Dev Cell. 2023 Apr 10;58(7):597-615.e10 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
Elsy Buitrago-Delgado, Ph.D., shares how spatial analysis of RNA distribution during early mouse embryogenesis suggests that the first cell fate choice is made at the 4-cell stage. She also discusses how notch signaling regulates cell fate choices during early human development. Series: "Stem Cell Channel" [Science] [Show ID: 38888]
Elsy Buitrago-Delgado, Ph.D., shares how spatial analysis of RNA distribution during early mouse embryogenesis suggests that the first cell fate choice is made at the 4-cell stage. She also discusses how notch signaling regulates cell fate choices during early human development. Series: "Stem Cell Channel" [Science] [Show ID: 38888]
Elsy Buitrago-Delgado, Ph.D., shares how spatial analysis of RNA distribution during early mouse embryogenesis suggests that the first cell fate choice is made at the 4-cell stage. She also discusses how notch signaling regulates cell fate choices during early human development. Series: "Stem Cell Channel" [Science] [Show ID: 38888]
Elsy Buitrago-Delgado, Ph.D., shares how spatial analysis of RNA distribution during early mouse embryogenesis suggests that the first cell fate choice is made at the 4-cell stage. She also discusses how notch signaling regulates cell fate choices during early human development. Series: "Stem Cell Channel" [Science] [Show ID: 38888]
Elsy Buitrago-Delgado, Ph.D., shares how spatial analysis of RNA distribution during early mouse embryogenesis suggests that the first cell fate choice is made at the 4-cell stage. She also discusses how notch signaling regulates cell fate choices during early human development. Series: "Stem Cell Channel" [Science] [Show ID: 38888]
Ali H. Brinvanlou, Ph.D., shares his work using in vitro attached human embryos and genome-edited synthetic embryos derived from human embryonic stem cells to learn the molecular, cellular, and embryological basis of early human development. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38324]
Ali H. Brinvanlou, Ph.D., shares his work using in vitro attached human embryos and genome-edited synthetic embryos derived from human embryonic stem cells to learn the molecular, cellular, and embryological basis of early human development. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38324]
Ali H. Brinvanlou, Ph.D., shares his work using in vitro attached human embryos and genome-edited synthetic embryos derived from human embryonic stem cells to learn the molecular, cellular, and embryological basis of early human development. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38324]
Ali H. Brinvanlou, Ph.D., shares his work using in vitro attached human embryos and genome-edited synthetic embryos derived from human embryonic stem cells to learn the molecular, cellular, and embryological basis of early human development. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38324]
Shiri Gur-Cohen, Ph.D., UC San Diego, explains how her lab studies how epithelial stem cells communicate with their vascular microenvironment to advance regeneration and combat metastatic diseases. Series: "Stem Cell Channel" [Education] [Show ID: 38409]
Shiri Gur-Cohen, Ph.D., UC San Diego, explains how her lab studies how epithelial stem cells communicate with their vascular microenvironment to advance regeneration and combat metastatic diseases. Series: "Stem Cell Channel" [Education] [Show ID: 38409]
Shiri Gur-Cohen, Ph.D., UC San Diego, explains how her lab studies how epithelial stem cells communicate with their vascular microenvironment to advance regeneration and combat metastatic diseases. Series: "Stem Cell Channel" [Education] [Show ID: 38409]
References Frontiers in Immunology November 2014. 21(578):1 Clin Epigenetics. 2017; 9: 94 Cancer Cell International September 2020. 20(1):429 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
Dr. Shuibing Chen is the Kilts Family Professor of Surgery at Weill Cornell Medicine. Her lab uses hiPSCs and ESCs for disease modeling and drug screening, with a focus on diabetes and infectious diseases such as Zika and SARS-CoV-2. She talks about her recent genome-wide association study in a dish, the role of philanthropic funding in stem cell research, and the role of industry partnerships in translational research.
What if we could trick stem cells into thinking they were young again? What would the impact be on human health and aging? Shiri Gur-Cohen, Ph.D., shares her work. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38216]
What if we could trick stem cells into thinking they were young again? What would the impact be on human health and aging? Shiri Gur-Cohen, Ph.D., shares her work. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38216]
What if we could trick stem cells into thinking they were young again? What would the impact be on human health and aging? Shiri Gur-Cohen, Ph.D., shares her work. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38216]
What if we could trick stem cells into thinking they were young again? What would the impact be on human health and aging? Shiri Gur-Cohen, Ph.D., shares her work. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38216]
What if we could trick stem cells into thinking they were young again? What would the impact be on human health and aging? Shiri Gur-Cohen, Ph.D., shares her work. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38216]
What challenges does aging pose to both individuals and society at large? What causes aging at the cellular and molecular level? Stem cell research is be key to finding solutions that increase our healthspan and change how we think about aging. Robert A.J. Signer, Ph.D., shares what is on the horizon. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38215]
What challenges does aging pose to both individuals and society at large? What causes aging at the cellular and molecular level? Stem cell research is be key to finding solutions that increase our healthspan and change how we think about aging. Robert A.J. Signer, Ph.D., shares what is on the horizon. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38215]
What challenges does aging pose to both individuals and society at large? What causes aging at the cellular and molecular level? Stem cell research is be key to finding solutions that increase our healthspan and change how we think about aging. Robert A.J. Signer, Ph.D., shares what is on the horizon. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38215]
What challenges does aging pose to both individuals and society at large? What causes aging at the cellular and molecular level? Stem cell research is be key to finding solutions that increase our healthspan and change how we think about aging. Robert A.J. Signer, Ph.D., shares what is on the horizon. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38215]
What challenges does aging pose to both individuals and society at large? What causes aging at the cellular and molecular level? Stem cell research is be key to finding solutions that increase our healthspan and change how we think about aging. Robert A.J. Signer, Ph.D., shares what is on the horizon. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38215]
Can we leverage stem cells to help live longer, healthier lives? Robert A.J. Signer, Ph.D., and Shiri Gur-Cohen, Ph.D., examine the process of aging at the molecular and cellular level to show how stem cells may be the key to preventing age-related health problems. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37968]
Can we leverage stem cells to help live longer, healthier lives? Robert A.J. Signer, Ph.D., and Shiri Gur-Cohen, Ph.D., examine the process of aging at the molecular and cellular level to show how stem cells may be the key to preventing age-related health problems. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37968]
Can we leverage stem cells to help live longer, healthier lives? Robert A.J. Signer, Ph.D., and Shiri Gur-Cohen, Ph.D., examine the process of aging at the molecular and cellular level to show how stem cells may be the key to preventing age-related health problems. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37968]
Can we leverage stem cells to help live longer, healthier lives? Robert A.J. Signer, Ph.D., and Shiri Gur-Cohen, Ph.D., examine the process of aging at the molecular and cellular level to show how stem cells may be the key to preventing age-related health problems. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37968]
Can we leverage stem cells to help live longer, healthier lives? Robert A.J. Signer, Ph.D., and Shiri Gur-Cohen, Ph.D., examine the process of aging at the molecular and cellular level to show how stem cells may be the key to preventing age-related health problems. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37968]
Can we leverage stem cells to help live longer, healthier lives? Robert A.J. Signer, Ph.D., and Shiri Gur-Cohen, Ph.D., examine the process of aging at the molecular and cellular level to show how stem cells may be the key to preventing age-related health problems. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37968]
Dr. Lydia Finley is an Assistant Member of the Cell Biology Program at Memorial Sloan Kettering Cancer Center. The Finley lab investigates how cellular metabolic pathways regulate cell fate decisions in stem cells and cancer cells. She talks about the metabolic profiles and needs of different cell types, her lab's discovery of an alternate TCA cycle, and how track and field led her to pursue metabolism research.
References Dr. Guerra's notes The Journal of Nutrition, Volume 137, Issue 3, March 2007, Pages 548–553 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
References Dr. Guerra's synthesis of the epitranscriptome lecture notes Sci Signal. 2017 Jan 31; 10(464): eaaf7478. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
References Dr Guerra's lecture notations and synthesis Cell. 2014 Dec 18; 159(7): 1615–1625 Nat Commun. 2020; 11: 102. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
References Guerra lecture notes/ideas Genes (Basel). 2014 Dec; 5(4): 865–886. Molecular Therapy—Nucleic Acids (2015) 4, e252 Int. J. Mol. Sci. 2016, 17(5), 719 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
Dan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]
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