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In this episode of ASCP Esty Talk, Maggie and Ella are joined by molecular biologist Dr. David Stachura to break down the science behind stem cells in skincare. Dr. David breaks down the differences between mammalian and plant stem cells, growth factors, exosomes, and why understanding these distinctions matters. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire. About Dr. David Stachura Dr. David Stachura has a B.S. in Molecular Biology from Lehigh University and a Ph.D. in Cellular and Molecular Biology from the University of Pennsylvania and performed his postdoctoral studies at the University of California San Diego. He is a stem cell biology expert and biotechnology executive specializing in regenerative medicine and innovative skincare solutions. As the Chief Scientific Officer (CSO) and Chief Operating Officer (COO) of SpecBio and FACTORFIVE Skincare, Dr. Stachura drives the development of cutting-edge wound healing therapies and cosmetic advancements. Previously directing the Stachura Lab, his breakthrough research in developmental biology, immunology, hematopoiesis, and stem cells has been widely published in peer-reviewed scientific manuscripts. Recognized for securing prestigious competitive NIH grants and advancing translational medicine, Dr. Stachura bridges the gap between complex laboratory science and commercial marketplace applications. Based in Chico California, Dr. David Stachura continues to lead industry advancements in cellular biology, helping biotechnology companies scale their scientific research, product development, and clinical strategy. About Ella Cressman: Ella Cressman is a licensed esthetician, certified organic formulator, and business owner with more than 20 years of experience in corrective skin care. Known as an "ingredient junkie" and industry cheerleader, she empowers professionals to think beyond products and develop a deeper understanding of skin function and formulation. In addition to her practice, Cressman is the founder of the HHP Collective, a practitioner-led community focused on strengthening clinical reasoning and advancing professional growth within the esthetics industry. Connect with Ella Cressman: Website: www.hhpcollective.com LinkedIn: linkedin.com/in/ella-cressman-62aa46a About Maggie Staszcuk: Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers. Connect with Maggie Staszcuk: P: 800.789.0411 EXT 1636 E: MStaszcuk@ascpskincare.com About our Sponsors: Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy GlossGenius Gaps in your schedule. Clients who don't rebook. Tight margins. High payment processing fees. Sound familiar? When you're running your own practice, you don't have time to figure out where you could be making more money. Especially when you're stitching together booking, payments, and a clunky EMR that only makes things harder. That's why we love GlossGenius — the business management platform that does the work for you. It fills your calendar, rebooks clients automatically, upsells high-margin services, and has the lowest flat-rate payment processing fees. Plus, all the HIPAA-compliant tools you need for charting, consents, and client records — without the admin chaos. GlossGenius grows your revenue and handles the busywork, so you can focus on your clients. Use code ESTY at GlossGenius.com for 50% off your first two months of their Gold or Platinum plan. GlossGenius. More Growth. Less Busywork. Visit https://glossgenius.com/ascp for more details. About Associated Skin Care Professionals (ASCP): Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member. Connect with ASCP: Website: www.ascpskincare.com Email: getconnected@ascpskincare.com Phone: 800-789-0411 Facebook: facebook.com/ASCPskincare Instagram: @ascpskincare
Os avanços da ciência transformaram o tratamento dos cânceres hematológicos,ampliando as possibilidades terapêuticas e contribuindo para o aumento da sobrevida depacientes com doenças como o mieloma múltiplo. Ainda assim, diagnóstico, recaídas,acesso ao tratamento e qualidade de vida permanecem entre os desafios da jornada.¹ ⁴Neste episódio do podcast Notícia no Seu Tempo, a jornalista Carla Fiorio conversacom os hematologistas Walter Moisés Tobias Braga, médico responsável peloAmbulatório de Mieloma Múltiplo da Universidade Federal de São Paulo (SP 114081);e Deise Almeida (SP 149683), médica e diretora médica de Oncologia e Hematologia daGSK Brasil, sobre mieloma múltiplo e mielofibrose, duas doenças que fazem parte douniverso da onco-hematologia. A conversa aborda os avanços da medicina, asnecessidades que ainda não foram atendidas e as perspectivas para o futuro do cuidado. Este episódio é uma produção do Estadão Blue Studio com patrocínio da GSK.Referências para o texto de apresentação: 1. Nooka AK, Kastritis E, Dimopoulos MA. Treatment options for relapsed andrefractory multiple myeloma. Blood. 2015;125(20).2. Hungria V, et al. Emerging Real-World Treatment Patterns and ClinicalOutcomes of Multiple Myeloma in Argentina and Brazil: Insights from theTOTEMM Study in the Private Healthcare Sector. Curr Oncol. 2026;33:16.3. Eisfeld C, et al. Time trends in survival and causes of death in multiple myeloma.BMC Cancer. 2023.4. IQVIA Institute. Global Oncology Trends 2025.Referências para o episódio: 1. Nooka AK, Kastritis E, Dimopoulos MA. Treatment options for relapsed andrefractory multiple myeloma. Blood. 2015;125(20). REF-480872. CA: A Cancer Journal for Clinicians. Vol. 70. 2020. p. 7–30. REF-724913. Kazandjian D. Multiple myeloma epidemiology and survival: A uniquemalignancy. Semin Oncol. 2016;43(6):676–81. REF-2960414. Hungria, V.; Maiolino, A.; Pessoa de Magalhães, R.J., Filho; Pitombeira deLacerda, M.; Remaggi, G.; Scibona, P.; Seehaus, C.; Brulc, E.; Savoy, N.; Fantl,D.; et al. Emerging Real-World Treatment Patterns and Clinical Outcomes ofMultiple Myeloma in Argentina and Brazil: Insights from the TOTEMM Studyin the Private Healthcare Sector. Curr. Oncol. 2026, 33, 16.https://doi.org/10.3390/curroncol33010016. REF-316596 5. Khoury JD, Solary E, Abla O, Akkari Y, Alaggio R, Apperley JF, et al. The 5thedition of the World Health Organization Classification of HaematolymphoidTumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia.2022;36:1703–1719. doi:10.1038/s41375-022-01613-1 REF-2279396. Eisfeld C. et al. Time trends in survival and causes of death in multiplemyeloma. BMC Cancer. 2023. REF-3161117. IQVIA Institute. Global Oncology Trends 2025. REF-3191028. Observatório de Oncologia. Panorama do Mieloma Múltiplo no SUS [acesso emjul2026]. https://observatoriodeoncologia.com.br/estudos/cancer-de-sangue/mieloma-multiplo/2024/panorama-do-mieloma-multiplo/ REF-2963359. International Myeloma Foundation Latin America. Mieloma múltiplo: segundotipo de câncer sanguíneo mais frequente no mundo [Internet]. São Paulo: IMFLA; 2022 jun 07 [acesso em jul2026]. https://myeloma.org.br/mieloma-multiplo-segundo-tipo-de-cancer-sanguineo-mais-frequente-no-mundo/. REF-26981910. Kumar SK et al. Multiple Myeloma. Nature Reviews Disease Primers. 2017.REF-1817111. Yu B et al. BCMA-targeted immunotherapy for multiple myeloma. Journal ofHematology & Oncology. 2020. REF-10177912. Wang R et al. Antibody–Drug Conjugates (ADCs): current and futurebiopharmaceuticals. Journal of Hematology & Oncology. 2025. REF-28457113. Scherber RM, Mesa RA. Management of challenging myelofibrosis after JAKinhibitor failure. Blood Reviews. 2020. REF-16832614. Nicolosi M et al. Sex and degree of severity influence the prognostic impact ofanemia in primary myelofibrosis. Leukemia. 2018. REF-30724015. Mughal TI et al. Myelofibrosis-associated complications. International Journalof General Medicine. 2014. REF-16520816. Naymagon L, Mascarenhas J. Myelofibrosis-Related Anemia: Current andEmerging Therapeutic Strategies. Hemasphere. 2017. REF-16521017. OJJAARA® (momelotinibe). Bula do produto; Consulta Pública ANS sobreincorporação para mielofibrose. REF-32111518. Hungria, V; et al. Belantamab mafodotin plus bortezomib and dexamethasone inpatients with relapsed or refractory multiple myeloma (DREAMM-7): updatedoverall survival analysis from a global, randomised, open-label, phase 3 trial.Lancet Oncol 2025 Published Online July 15, 2025 https://doi.org/10.1016/S1470-2045(25)00330-4. REF-24715319. Mukhopadhyay, P., Abdullah, H.A., Opalinska, J.B. et al. The clinical journey ofbelantamab mafodotin in relapsed or refractory multiple myeloma: lessons indrug development. Blood Cancer J. 15, 15 (2025).https://doi.org/10.1038/s41408-025-01212-0. REF-24715320. ABBAS, A. K.; LICHTMAN, A. H.; PILLAI, S. Cellular and molecularimmunology. 10. ed. Philadelphia: Elsevier, 2022. REF-30571621. BIRGEGARD, G. et al. Inflammatory functional iron deficiency common inmyelofibrosis, contributes to anaemia and impairs quality of life. EuropeanJournal of Haematology, 2019; 102:235–240. REF-32205922. Al Noumani I; Expert Opinion on Pharmacotherapy; 2026; 27(8), 657–668.REF-331446 Material dirigido ao público geral. Por favor, consulte o seu médico. NP-BR-MMU-WCNT-260004/SETEMBRO DE 2026See omnystudio.com/listener for privacy information.
You might think eating clean is enough to stay young, but new research says otherwise. One in five people over 50 already have one organ aging faster than the rest of their body. Dr. Will Cole joins Gary Brecka to break down insulin resistance, blood sugar, cellular aging, mold and EMF toxicity, and SymphonyAge, the new DNA test that reveals exactly which organ is aging you fastest, from his book Heal Your Cells. Click here to join Gary's VIP Community!: https://bit.ly/4ai0Xwg Get Dr. Will Cole's book, “The Inflammation Spectrum”: https://amzn.to/4jnQe7r Listen to “ Dr. Will Cole “ on all your favorite platforms! YouTube:https://bit.ly/4jmEv9c Spotify: https://bit.ly/3Tu7Iaw Apple Podcasts: https://bit.ly/4xXaX8x Connect with Dr. Will Cole: Website:https://bit.ly/4iurxF0 YouTube: https://bit.ly/4jmEv9c Instagram:https://bit.ly/3GlSihK Facebook:https://bit.ly/4lGTEUh TikTok:https://bit.ly/4444EVw X.com: https://bit.ly/4cI59qw Thank you to our partners A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD AIRES: “ULTIMATE20” FOR 20% OFF: https://bit.ly/4a3Duze BAJA GOLD: “ULTIMATE10” FOR 10% OFF: https://bit.ly/3WSBqUa BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp CYMBIOTIKA: “BRECKACYM30” FOR 30% OFF: https://bit.ly/4tjyluP GENETIC METHYLATION TEST (UK ONLY): https://bit.ly/48QJJrk GENETIC TEST (USA ONLY): https://bit.ly/3Yg1Uk9 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn SNOOZE: LET'S GET TO SLEEP!: https://bit.ly/4pt1T6V WHOOP: JOIN & GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW Watch the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 Intro of the Show 01:17 Dr. Will Cole on Cellular Health 04:45 How to Heal Leaky Gut Naturally 08:42 Intermittent Fasting for Gut Health 09:47 SIBO, H. Pylori & Fermented Foods 13:16 Heal Your Cells Book by Dr. Will Cole 16:55 Why Millennials Are Aging Faster 20:18 Epigenetics & Cellular Aging 26:59 Mitochondria & Best Longevity Blood Tests 30:10 Biological Age Test for Organs 33:00 Mold Toxicity & Histamine Intolerance 36:38 How to Manage Chronic Stress 39:08 Journaling for Stress & Trauma 43:02 Best Foods for Detox & Cell Repair 49:14 Therapeutic Plasma Exchange & Stem Cells 54:52 What It Means to Be an Ultimate Human Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions. Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation. Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature. Learn more about your ad choices. Visit megaphone.fm/adchoices
Send us Fan MailWhy do so many of us feel tired, even when we're trying to take care of ourselves? In this episode of It's Hertime, Cody talks with Tim James, founder of Chemical Free Body, about how the body creates energy and what may get in the way.They explore cellular energy, the difference between supporting energy and relying on stimulants, and everyday habits that can support how the body functions. Tim also shares his personal health journey and perspective on detoxification and environmental toxins. The conversation touches on fasting, too, including his experience with a 40-day juice fast and why fasting may not be the right starting point for everyone—especially women in perimenopause and menopause who are already feeling fatigued or undernourished.In this episode, you'll hear about:Tim's health journey and the changes that shifted his pathWhat cellular energy means and why you may still feel tiredThe difference between creating energy and stimulating it with caffeineEveryday habits that support energy and the body's natural detoxificationWhat “detox” means and common misconceptionsSimple ways to reduce exposure to environmental toxinsTim's 40-day juice fast and what it taught himHow to think about fasting when energy is already lowA practical first step for listeners who feel exhaustedAbout Tim JamesTim James is the founder of Chemical Free Body. After a serious decline in his own health, he transformed his lifestyle and has spent the past decade helping people explore nutrition, detoxification strategies, and daily habits that may support better energy.Connect with Tim:Chemical Free BodyInstagramYouTubeTikTokTim James Unleashed podcastThis conversation is for educational purposes and isn't a substitute for individualized medical advice. Your health history, nutrition, stress, sleep, and other factors can affect what approach is right for you.Did you learn something new today? Be sure to subscribe to this podcast and share this episode with all the girls you love. We would appreciate it if you'd also leave us a rating and review on iTunes.Want to join our Mixhers Girl community and keep this conversation going? We'd love to hear your thoughts, feelings and experiences! Join us HERE!Join Mixhers email list and be the first to have access to new products and be the girl in the know!Follow Cody Instagram:@codyjeansanders
BUFFALO, NY — September 29, 2026 — A new #review was #published in Volume 18 of Aging on September 8, 2026, titled “Developmental senescence misregulation in congenital disorders: CHARGE syndrome as a candidate model.” The article proposes that disruption of developmental senescence—a tightly controlled cellular program involved in embryonic tissue remodeling—may contribute to congenital abnormalities associated with CHARGE syndrome. The review was led by co-first authors Álvaro J. Arana and Pablo Palau-Irisarri, who contributed equally. Arana is affiliated with the Departamento de Zoología, Genética y Antropología Física, Facultad de Veterinaria, Universidad de Santiago de Compostela, Spain, while Palau-Irisarri is affiliated with the Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, Spain. Arana is also the corresponding author. Cellular senescence is commonly associated with aging, cellular stress and tumor suppression, but it also occurs naturally during embryonic development. Unlike classical stress-induced senescence, developmental senescence is transient and restricted to particular tissues and developmental stages. These cells can contribute to tissue remodeling and patterning before being cleared, helping shape developing organs. Because this process must occur at the right place and time, the authors propose that excessive, insufficient, prolonged or misplaced senescence could interfere with normal morphogenesis. CHARGE syndrome provides a particularly relevant model for investigating this possibility. The rare developmental disorder can involve coloboma, heart defects, choanal atresia, growth and developmental delay, genitourinary abnormalities and characteristic ear defects. Most patients with CHARGE syndrome carry pathogenic variants in CHD7, which encodes an ATP-dependent chromatin remodeler. Full press release - https://www.aging-us.com/news-room/developmental-senescence-emerges-as-a-candidate-mechanism-in-charge-syndrome DOI - https://doi.org/10.18632/aging.206396 Corresponding author - Álvaro J. Arana - alvaro.arana@usc.es Abstract video - https://www.youtube.com/watch?v=QtB5390b1To Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206396 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, CHD7, morphogenesis, p53/p21 pathway, TGFβ signaling, congenital disorders To learn more about the journal, please visit https://www.Aging-US.com and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
What if one of the biggest keys to energy, brain function and healthy aging is happening inside the microscopic powerhouses of your cells? Patty Greer and C60 Evo founder Chris Burres return to Unleashing Intuition Secrets with Michael Jaco for a fascinating conversation about mitochondrial function, longevity and the cellular processes associated with some of the most feared diseases of aging. Chris breaks down the science connecting mitochondrial dysfunction with heart disease, cancer, type 2 diabetes, Alzheimer's and dementia—and explains why supporting healthy mitochondrial function has become such an important area of research. The conversation then turns to ESS60, C60 Evo's proprietary high-purity form of carbon 60. Its distinctive soccer-ball-shaped molecular structure has made C60 an area of scientific interest for decades, particularly for its antioxidant properties and interactions with free radicals. Chris explains why C60 Evo combines ESS60 with carefully selected extra virgin olive oil, creating the lipid environment needed for stability and consistency—and why the quality and purity of that olive oil matters. Patty brings the human side of the conversation, sharing personal experiences and testimonials from people who use C60 Evo, including her 97-year-old mother. Michael also shares why C60 Evo has become part of his own wellness routine. And then there's the longevity research that started so much of the fascination with C60: the panel discusses the famous Wistar rat study, in which rats receiving C60 dissolved in olive oil lived substantially longer than comparison groups. The speakers discuss what that research could mean while emphasizing that animal results do not establish the same lifespan effect in humans. Mitochondria. Cellular energy. Antioxidants. Brain function. Longevity. This conversation gets to the cellular level of aging—and explores why Chris and Patty believe supporting the mitochondria may be one of the most important pieces of the wellness puzzle.
JR Ortiz's personal fat-to-fit transformation using Macro Greens® led to why it worked when nothing else did. Though his studies and building the sales team he became the lead formulator and is now the President of MacroLife Naturals. JR is devoted to bridging the gap between allopathic and holistic medicine, building formulas that feed the body at the cellular level while making them complementary to commonly prescribed medications and absolutely delicious!JR worked on the Corporate Advisory Board of the UCLA School of Nursing as the official liaison for UCLA into the Natural Products Industry. He remains the youngest board member ever at UCLA since his appointment in 2008.Contact JR Ortiz:https://macrolifenaturals.com/https://www.instagram.com/macrolife_naturals/Dr. Kimberley LinertSpeaker, Author, Broadcaster, Mentor, Trainer, Behavioral OptometristEvent Planners- I am available to speak at your event. Here is my media kit: https://brucemerrinscelebrityspeakers.com/portfolio/dr-kimberley-linert/To book Dr. Linert on your podcast, television show, conference, corporate training or as an expert guest please email her at incrediblelifepodcast@gmail.com or Contact Bruce Merrin at Bruce Merrin's Celebrity Speakers at merrinpr@gmail.com702.256.9199Host of the Podcast Series: Incredible Life Creator PodcastAvailable on...Apple: https://podcasts.apple.com/us/podcast/incredible-life-creator-with-dr-kimberley-linert/id1472641267Spotify: https://open.spotify.com/show/6DZE3EoHfhgcmSkxY1CvKf?si=ebe71549e7474663 and on 9 other podcast platformsAuthor of Book: "Visualizing Happiness in Every Area of Your Life"Get on Amazon: https://amzn.to/4cmTOMwThe Great Discovery eLearning platform: https://thegreatdiscovery.com/kimberleyl
On the campaign trail, President Trump promised to declassify the 9/11 files; on September 11, 2001, he told New York television the World Trade Center was an “unbelievably powerful” structure and said he could not imagine an aircraft alone penetrating its exterior steel, even questioning whether additional explosions had occurred. Twenty-five years later, Brad Wozny revisits the lives lost, the heroism he witnessed at Ground Zero, his extraordinary journey 18 stories beneath the Pentagon, the Patriot Act and War on Terror that followed, and the unanswered questions still driving Americans to demand full disclosure, truth and justice...on a day Brad also marks as Christ's birthday. .
Dr. Will Cole goes solo to dig into the science behind cellular confusion, why your cells forget what they're created to do, and what to do about it. In this deep dive, he breaks down the "Inflammatory Core Four" (sugar, seed oils, grains, and dairy), the concept of xenohormesis, and how fasting and food timing activate autophagy, mitophagy, and your body's own cellular repair pathways. For all links mentioned in this episode, visit http://www.drwillcole.com/podcastPlease note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.SPONSORS:Go to HANSforDogs.com/WELL and make sure to use the code WELL get $30 off your first month. Plus, every order is backed by a 90-day money-back guarantee, so you can try HANS completely risk-free. HANS™. Tested on humans, perfected for dogs.Visit DRINKAG1.com/willcole and get an AG1 Pro YETI Shaker in your AG1 Pro Welcome Kit. EllaOla is offering my listeners 20% off your first purchase. Just go to EllaOla.com/WILLCOLE, discount applied automatically; No code needed.Head to MANUKORA.com/WILLCOLE and use code WILLCOLE to save up to 31% plus $75 worth of free gifts with the Starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, a guidebook, and an onboarding call with Manukora's clinical nutritionist.You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/WILLCOLE and using code WILLCOLE at checkout.Text ABW to 64000 to get twenty percent off all IQBAR products, plus FREE shipping. Message and data rates may apply.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Still the most commonly drug prescribed for people with diabetes (and the third most commonly prescribed drug in the US!) but what is it and what is it doing? Kelly and Erin talk through the very beginning of it's story to where we are now and everything in between. References:LaMoia TE, Shulman GI. Cellular and Molecular Mechanisms of Metformin Action. Endocr Rev. 2021;42(1):77-96. doi:10.1210/endrev/bnaa023American Diabetes Association Professional Practice Committee for Diabetes. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes-2026. Diabetes Care. 2026;49(Suppl 1):S183-S215. doi:10.2337/dc26-S009Pavlo Petakh, Kamyshna I, Kamyshnyi A. Effects of metformin on the gut microbiota: A systematic review. Mol Metab. 2023 Nov;77:101805. doi: 10.1016/j.molmet.2023.101805. Epub 2023 Sep 9. PMID: 37696355; PMCID: PMC10518565.Bu Y, Peng M, Tang X, et al. Protective effects of metformin in various cardiovascular diseases: Clinical evidence and AMPK-dependent mechanisms. J Cell Mol Med. 2022;26(19):4886-4903. doi:10.1111/jcmm.17519 LINKS:Email us your questions here: glucoseriotpod@gmail.comFind out more about Kelly at www.sixnutritionanddiabetes.comFind out more about Erin at www.erinphillipsnutrition.comDISCLAIMER: We are dietitians and diabetes educators but we are not YOUR dietitians and diabetes educators. The information provided in this podcast is not intended as individualized medical advice, nor is it a substitute for professional medical expertise or treatment. If you have a medical concern, go to your health care provider or seek other professional medical treatment.
Cellular Agriculture Livestock farming is a major driver of global greenhouse gas emissions, deforestation, and water consumption, yet global demand for meat continues to rise. Cellular agriculture offers an alternative by cultivating meat from animal cells in a bioreactor. This could significantly reduce the climate and environmental impacts of meat production while delivering the same quality of meat consumers love. Cells to Meat - How and WhyCurrent food production systems, particularly for meat, can be among the most harmful human activities for the environment. They often require vast amounts of fresh water and land, are a major source of water pollution, and contribute to about one third of the world's greenhouse gas emissions. Yet, the demand for meat continues to rise, with the Food and Agriculture Organization of the United Nations projecting the demand to reach 445 M metric tons by 2050, which is a 76 percent increase from 2005. Cultured, or cell-based, meat has the potential to remedy these issues. Meat cultured in a bioreactor can avoid harming animal welfare, producing methane, or spreading food-borne diseases, and promotes a more humane, sustainable, and safe way to consume meat without substantial change to consumption habits. Cultured meat is created by taking cells from an animal and growing them in bioreactors. Through controlling temperature, exposure to nutrients, and other aspects, the cells can be tricked into believing that they are still inside of an animal. Under these carefully monitored conditions, the cells divide and proliferate, or grow exponentially, and mature into muscle and fat tissue through a process called differentiation. The Potential and the ChallengesAdvocates for cultured beef project that it will use less land and water, and produce less greenhouse gas emission compared to farmed beef. Cultured meat additionally has the potential to benefit public health by reducing the spread of food-borne illness, infectious disease, and antimicrobial resistance. Farmed meat can carry countless pathogens, including zoonotic diseases, or diseases that can be passed from animal to human, such as influenza A. During the pandemic, meat-packing plants experienced multitudes of COVID-19 outbreaks. Cell-based meat production is conducted under more sterile conditions, so it has a lower chance of spreading such pathogens.Despite the promising potential of cultured meat, it faces many challenges when it comes to commercialization. The primary concern of lab-grown meat is the cost. Media, or the food the cells use, is extremely expensive, and bioreactors, which were originally designed to cultivate small quantities of cells at a time, still need to be scaled. Cells are also finicky, so when conditions are unfavorable, they stop growing. With large vessels it is difficult to ensure that the conditions are always optimal for growth. Due to these high production costs, some estimates of the potential cost of cultured meat are approximately $37 per kilogram, which is 10 times more expensive than the cost of regular meat.In addition, many studies have shown that attitudes towards lab-grown meat are mixed, with some customers having concerns about the ‘unnaturalness' and about the safety of the product. One study showed that although 65 percent of respondents were willing to try cell-based meat, only approximately 33 percent were willing to eat it regularly or as a replacement for farmed meat. To gain consumer acceptance, the lab-grown alternative must be at a minimum equivalent, if not superior in quality to that of regular meat, which can be especially challenging for meats that require structure, like steak. Natalie Rubio's PerspectiveNatalie Rubio believes that despite the challenges cell-based meats face, there is tremendous potential and that areas in which current technology is lacking are simply opportunities for new technologies to develop. Rubio co-founded Deco Labs to take on some of the challenges posed to cultured meat and develop solutions to them. Currently, Deco Labs are experimenting with genetic engineering to make the cells more productive and with creating cheaper media to feed the cells and lower the cost of production. Natalie Rubio believes that despite the current cost of cultured meat, cheaper inputs can lead cell-based meats to becoming cheaper than conventional meat. About our GuestNatalie Rubio was one of the first interns at New Harvest and later became a New Harvest Research Fellow. As a fellow, Rubio completed her Ph.D. at Kaplan Lab at Tufts University, being among the first in the world to complete a Ph.D. in cellular agriculture. Currently, Natalie Rubio is a co-founder and CEO of Deco Labs. ResourcesTEDx Talks, Natalie Rubio on the Journey of Cellular AgricultureFraser et al, The Foundations of Cellular Agriculture Rubio et al, Plant-based and cell-based approaches to meat productionEconomics Research Service USDA, The Economics of Cellular AgricultureNew Harvest, Natalie Rubio among world's first cellular agriculture Ph.DA transcript of this episode can be found at https://climatebreak.org/growing-meat-from-cells-with-dr-natalie-rubio/
OVERVIEW: In this insightful interview, Kate Deering shares her 30+ years of experience in health, fitness, and nutrition, emphasizing the importance of metabolic health, energy production, and personalized dietary approaches. Discover how understanding cellular energy can transform your health, improve hormonal balance, and support sustainable wellness practices. Inside this episode, Ashley and Kate discuss: Cellular energy and ATP production Impact of diet and stress on metabolism Role of carbohydrates and nutrients in health RESOURCES: Check out Kate's website here: www.katedeering.com Join my Rise workout program HERE: https://www.metabolicfix.com/rise Click here to schedule your FREE alignment call to see if my 1:1 coaching program is a good fit for you: https://app.acuityscheduling.com/schedule/7de98067/appointment/18062930/calendar/4677043?appointmentTypeIds%5B%5D=18062930 Email us at: Support@metabolicfix.com Click here to learn more about my 1:1 coaching program https://metabolicfix.com/one Take My PHASE ASSESSMENT QUIZ HERE: https://www.metabolicfix.com/phase-quiz Follow Ashley on Instagram: @ashley_fillmore1 Want to see which one of my programs is the best for you? Take my Services Quiz: https://www.metabolicfix.com/services-quiz Take my FREE Metabolic Damage Quiz here: https://metabolicfix.com/md-quiz
Scientific Sense ® by Gill Eapen: Prof. Mark Mattson is adjunct professor of neuroscience at Johns Hopkins University, School of Medicine. His research includes Cellular and Molecular Mechanisms of Brain Aging and Neurodegenerative Disorders. Please subscribe to this channel:https://www.youtube.com/c/ScientificSense?sub_confirmation=1
Two women. Two very different paths into wine. One seriously good conversation.On this episode of Wine Crush Podcast, Heidi sits down with Jeanne Feldkamp, co-founder and winemaker at Corollary Wines, and Rachel Rose, winemaker and vineyard director at Bryn Mawr Vineyards, for a deep dive into sparkling wine, science, farming, creativity, and the ever-evolving story of Oregon wine.Jeanne and her partner, Dan Diephouse, founded Corollary Wines with one very specific mission: explore what the Willamette Valley can express through traditional-method sparkling wine. After producing their first Oregon vintage in 2017, they went all-in on bubbles. In 2022, they purchased 57 acres in the Eola-Amity Hills and began developing a vineyard specifically designed for sparkling wine production, with regenerative agriculture at the heart of the project. Jeanne has also become a driving force in Oregon's growing sparkling-wine movement as a co-founder of Method Oregon. (Corollary Wines)Then there's Rachel Rose, whose road to wine began with science. With a degree in Molecular, Cellular and Developmental Biology from UC Santa Cruz, Rachel left biotech behind and headed to Australia, ultimately earning a master's degree in Oenology and postgraduate training in viticulture from the University of Adelaide. Her journey eventually brought her to Oregon and Bryn Mawr Vineyards, where she now directs both the vineyard and winemaking programs. Her approach combines biology, chemistry, experimentation and artistry, with a focus on letting each vintage and vineyard tell its own story. (Bryn Mawr Vineyards)From bubbles and microbiology to vineyard life, off-grid living, sustainability and the future of Oregon wine, this conversation goes in all the best directions.Pour something delicious and settle in. This is an episode filled with smart women, fascinating stories, plenty of laughs and a whole lot of Eola-Amity Hills energy.
Two women. Two very different paths into wine. One seriously good conversation.On this episode of Wine Crush Podcast, Heidi sits down with Jeanne Feldkamp, co-founder and winemaker at Corollary Wines, and Rachel Rose, winemaker and vineyard director at Bryn Mawr Vineyards, for a deep dive into sparkling wine, science, farming, creativity, and the ever-evolving story of Oregon wine.Jeanne and her partner, Dan Diephouse, founded Corollary Wines with one very specific mission: explore what the Willamette Valley can express through traditional-method sparkling wine. After producing their first Oregon vintage in 2017, they went all-in on bubbles. In 2022, they purchased 57 acres in the Eola-Amity Hills and began developing a vineyard specifically designed for sparkling wine production, with regenerative agriculture at the heart of the project. Jeanne has also become a driving force in Oregon's growing sparkling-wine movement as a co-founder of Method Oregon. (Corollary Wines)Then there's Rachel Rose, whose road to wine began with science. With a degree in Molecular, Cellular and Developmental Biology from UC Santa Cruz, Rachel left biotech behind and headed to Australia, ultimately earning a master's degree in Oenology and postgraduate training in viticulture from the University of Adelaide. Her journey eventually brought her to Oregon and Bryn Mawr Vineyards, where she now directs both the vineyard and winemaking programs. Her approach combines biology, chemistry, experimentation and artistry, with a focus on letting each vintage and vineyard tell its own story. (Bryn Mawr Vineyards)From bubbles and microbiology to vineyard life, off-grid living, sustainability and the future of Oregon wine, this conversation goes in all the best directions.Pour something delicious and settle in. This is an episode filled with smart women, fascinating stories, plenty of laughs and a whole lot of Eola-Amity Hills energy.
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Jodi Duval, and Dr. Allen Bookatz explore what happens inside the cell when the body perceives stress or danger. The discussion focuses on Dr. Robert Naviaux's Cell Danger Response and how mitochondria can alter energy production and signaling in response to perceived threats. The team examines why fatigue, brain fog, inflammation, and exercise intolerance can occur even when standard laboratory testing appears normal, and how the different phases of the cellular response are meant to move from defense through repair and recovery. Join us as we delve into: Stress at the Cellular Level: How mitochondria and cells respond when they perceive danger from infection, toxins, injury, environmental exposures, or psychological stress. Why Normal Labs May Not Explain Fatigue: Why standard testing may not capture changes in cellular signaling, mitochondrial output, or a cell's metabolic state. The Three Phases of the Cell Danger Response: How CDR1 involves inflammatory defense, CDR2 involves proliferation and rebuilding, and CDR3 involves differentiation and recovery. Stress, Mitochondria and Energy: Why cells may reduce energy output while continuing to interpret their environment as unsafe. Hormesis and Stress Dosing: Why exercise, temperature exposure, and other acute stressors may be useful when properly dosed, while excessive stress may add to the existing burden. Mitochondrial Nutrient Support: The role discussed for CoQ10, PQQ, magnesium, and NAD+ precursors in supporting the metabolic machinery during the transition through the CDR phases. Parasympathetic Safety Signaling: How extended-exhale breathing, HRV biofeedback, vagal tone work, and other approaches are discussed as ways to reduce chronic sympathetic input. The Limits of the Framework: Why deliberately adding stress to an already overloaded system may be counterproductive when the dose is not appropriate. Disease Management vs. Health Optimization: Why the HOMeHOPe approach looks not only at the trigger but also at the conditions the cell may need to complete its response. This episode is for you if: You experience fatigue, brain fog, or exercise intolerance despite relatively normal standard laboratory results. You want to understand the Cell Danger Response and its proposed role in cellular stress. You are interested in mitochondrial function, cellular energy, inflammation, and purinergic signaling. You want to understand why more exercise, stimulation, or stress is not always the right answer. You are interested in hormesis, autonomic regulation, gut health, circadian biology, and metabolomic testing. You want to understand how Health Optimization Medicine approaches cellular stress and recovery. You can also find this episode on… YouTube: https://youtu.be/0Vx79yABA9k Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
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Make a Logo on Fiverr The OBSBOT Talent 2 is the kind of production box that makes you question how much gear you really need for a live show. It combines a video switcher, recorder, streaming encoder, monitor and remote production system inside one portable unit. Add four HDMI inputs, network video support and four-channel ISO recording, and it starts looking like a serious alternative to an ATEM-based mobile setup. That flexibility comes with a $2,099 price tag, and there are a few physical design choices to consider. After unboxing and connecting csources, here is where the Talent 2 stands out. A Portable Studio With Room to Grow The Talent 2 is built around a 7-inch AMOLED touchscreen with a 1,920-by-1,080 resolution, 800-nit brightness, 10-bit color, a 100,000:1 contrast ratio and an anti-fingerprint coating. The display is bright and sharp indoors. OBSBOT also includes a sun shield for outdoor work, where even an 800-nit display can struggle in direct light. Its included stand holds the unit without blocking the connections and offers mounting points for accessories such as a microphone or light. A removable screen cover adds protection when the Talent 2 is packed for travel. This is a system designed to come out of a case, connect to cameras and start producing a show without requiring a separate monitor or computer. Four HDMI Inputs and Plenty of Network Sources Four HDMI inputs sit across the top of the unit. The Talent 2 also supports USB cameras and network sources including full-bandwidth NDI, NDI HX2, NDI HX3, SRT, RTSP and RTMP. IP sources can reach up to 4K at 60 frames per second, giving a producer several ways to bring in cameras, computers, phones and remote guests. In testing, I connected four HDMI devices, an OBSBOT Meet Flip over USB and multiple NDI sources, including an iPhone and an overhead camera. The Talent 2 handled individual feeds as well as layered layouts. I could resize sources, change their order and build a three-camera composition over a game feed directly on the touchscreen. The device can take 15-16 inputs comfortably, but it’s best to keep it around 7-8. Switch, Stream and Record From One Box The touchscreen interface provides quick access to inputs, scenes, graphics, audio and streaming controls. You can add lower thirds, titles, animated text, clocks, photos and prerecorded video. There are also tools for drawing on the program output, creating scene playlists, controlling PTZ cameras, adding timers and scoreboards, freezing a scene or fading to black. Four-Channel ISO Recording One of the Talent 2’s most important features is four-channel ISO recording. Instead of saving only the final switched program, it can record four isolated HDMI feeds for editing later. It supports MP4 and MOV recording with H.264 or H.265 encoding at up to 4K60. There is 128GB of internal storage, plus a microSD card slot and support for external USB storage. That combination makes the unit useful for live productions that also need editable camera originals. I had not yet completed a full ISO stress test at the time of this first hands-on review, so long-duration recording performance is one area I will continue to evaluate. Streaming to Four Destinations The Talent 2 can stream to as many as four destinations simultaneously, with native options for YouTube, Facebook, Twitch and Restream. It also supports RTMP, RTMPS, SRT, HLS and NDI HX3 output. Streaming resolutions range from 360p through 4K60, with a maximum published bitrate of 120Mbps, although the practical limit will depend on the available internet connection. Shows can run in standard 16:9 or vertical 9:16 orientation. That makes the Talent 2 useful for traditional livestreams as well as mobile-first productions. Two HDMI 2.0 outputs can deliver video at up to 4K60, while USB-C provides UVC and UAC output to a computer. The Ethernet port supports 2.5Gbps networking. Remote Production Is a Major Strength You do not have to operate the Talent 2 from its touchscreen. A browser-based interface works from a computer, tablet or phone on the same network. From there, I could switch sources, manage encoders, configure destinations, upload media and transfer recordings to a desktop for immediate post-production. The system also supports user profiles with limited controls. In a sports production, for example, one operator could manage audio from a tablet while another switches the show. The Talent 2 can create its own hotspot, which helps when a dedicated local control network is needed. Audio and Automatic Switching Two 3.5mm audio inputs can accept microphone or line-level sources, and a headphone output provides monitoring. Each source can be routed to the monitor and program mix, kept active across scene changes or turned off. The Video Follows Audio feature can automatically switch to the source associated with the person speaking, which could simplify panel discussions and interview shows. Designed for Work Away From the Studio Two battery bays on the rear support hot swapping, allowing one battery to be changed while the other keeps the Talent 2 running. Cellular support is built in through a SIM slot and external 5G antennas. Separate antenna connections cover Wi-Fi, and the package includes international power adapters and a locking USB-C cable. Multiple quarter-inch mounting points make it possible to place the unit on a tripod, arm or customized rig. For events, conferences, sports and mobile interviews, those mounting and power options are just as important as the switching features. The Biggest Problem: HDMI Port Spacing The four HDMI inputs are packed tightly together. With thicker cable ends—especially optical HDMI cables—it can be difficult or impossible to use every port without the connectors pressing against one another. I had to rearrange cables and find a thinner option to populate all four inputs. That pressure is not something I want on HDMI ports during a live production. Owners planning to use all four inputs should test their cable ends before an event and consider slim HDMI cables or compact adapters. A little more space between the ports would have made this much easier. I also saw a small amount of latency when comparing an NDI feed with a direct HDMI path. That is not unexpected when mixing network and wired video, and firmware updates may continue to improve performance, but timing is worth checking before combining source types in a production. Is the OBSBOT Talent 2 Worth $2,099? The Talent 2 is expensive compared with a basic hardware switcher (ATEM ISO around $600, ATEM Mini Extreme is $2,000), but the comparison changes once you add a monitor, streaming encoder, network video support, storage and remote control. OBSBOT has placed all of those tools in one battery-powered unit that can handle a surprisingly complex show. For a creator who only needs two HDMI cameras, the smaller and less expensive options will make more sense. For event producers, mobile studios and livestream teams that need four HDMI inputs, 4K streaming, isolated recordings and remote operation, the Talent 2 offers a compelling all-in-one workflow. The OBSBOT Talent 2 comes close to being the ultimate portable live studio because it removes so many separate boxes from the production chain. Its AMOLED display, flexible source support, four-channel ISO recording, remote interface and hot-swappable power give it serious potential as an ATEM replacement. It is not flawless. The cramped HDMI ports are a real frustration, the price puts it firmly in professional territory and some features deserve longer testing under live-show conditions. Still, few portable systems put this much switching, recording and streaming power into one package. OBSBOT provided the Talent 2 for this review but did not sponsor the video. The company had an opportunity to view the video before publication. All opinions are Geekazine.com. A 30-Day video will be produced next month. See it for yourself at https://geni.us/obsbottalent2 Check out the Geekazine Merch, including "I AM AI " T-Shirt. Thanks for reading! Don't forget to subscribe to Geekazine: RSS Feed - YouTubeTwitter - Facebook Support Monthly as a Patreon! with a free month! Tip Me via Paypal.me Send a Tip via Venmo RSS Bandwidth by Cachefly Get a 14 Day Trial Reviews: Geekazine gets products in to review. Opinions are of Geekazine.com. Sponsored content will be labeled as such. Read all policies on the Geekazine review page. Reviews: Geekazine is also an affiliate of Amazon.com - Check out my Amazon Page Last Updated on September 16, 2026 4:28 pm by Jeffrey PowersThe post OBSBOT Talent 2 Review: The Ultimate All-in-One Live Studio? appeared first on Geekazine.
Apple’s September 2026 keynote is in the books, and Pilot Pete, Adam Christianson, and Dave Hamilton are here to help you figure out what’s actually worth your money. You kick things off with the big question: what are your three favorite geeks gonna buy? They then dig into the reasons, starting with the Apple Watch Series 12 and Ultra 4: battery life, new health sensors, Live Rewind, Siri Recap, and an Audio Intelligence feature that really should’ve been called Audible Intelligence. Then it’s on to the star of the show, the iPhone Duo, where you get the real story on its price, how much storage you actually need, and that crease. And, oh yeah, MagSafe. From there, you’ll size up the iPhone 18 Pro and Pro Max and find out why Siri AI may be what finally pushes you to upgrade your hardware, and how iCloud+ quietly turned into an AI paywall. Before you sign up for Apple Upgrade, you’ll learn that the fine print calls it a lease. Then you get the lowdown on AirPods 5 and whether AppleCare One Family at $49.99 a month makes sense for your household. By the end, you’ll know whether all this talk changed anyone’s shopping list, and whether it should change yours. Don’t Get Caught overpaying for your next upgrade! 00:00:00 Mac Geek Gab 1159 for Monday, September 14th, 2026 September 14th: National Cream Filled Donut Day MGG Monthly Giveaway – Win a license to SuperDuper! 4 00:05:08 What are you gonna buy? Pete: AppleCare One Family, iPhone Duo Adam: iPhone 18 Pro, Apple Watch Series 12 Dave: iPhone Duo, Maybe an Apple Watch? 00:07:06 Apple Watch Series 12 / Ultra 4 Battery Life New Health Sensors Audio Intelligence (really should be Audible Intelligence) Live Rewind Siri Recap 00:18:07 Legal implications of tech that is always recording 00:20:38 Pete's thoughts on the Apple Watch Battery Life S11 Chip Bee app for listening 00:25:49 Cellular on Apple Watch US Mobile uses it Mint Mobile can't Sponsors 00:30:03 SPONSOR: Proton VPN. Unlike most VPNs, Proton is backed by strong European privacy laws, and, right now, Proton VPN is offering our listeners 70% off a two year plan when you go to https://ProtonVPN.com/MGG 00:31:08 SPONSOR: Hims is changing men's healthcare by providing convenient, quality care, 100% online. Start your free online visit today at https://Hims.com/MGG. 00:32:21 SPONSOR: CleanMyMac. Get Tidy Today! Try 7 days free and use our code MACGEEK for 20% off at https://clnmy.com/MACGEEK 00:33:42 iPhone Duo Linus Tech on iPhone Duo Marques Brown on iPhone Duo The price of the iPhone Duo Storage on an iPhone Duo 00:55:02 iPhone Duo has a crease 00:58:59 iPhone 18 Pro / Pro Max 01:04:24 Siri AI is the reason for a hardware upgrade iCloud+ quietly became an AI paywall 01:10:23 “Apple Upgrade” is a lease 01:13:53 AirPods 5 01:18:50 AppleCare One Family $49.99/mo for the Family Plan 01:29:58 Did this discussion change what you're gonna buy? 01:31:46 MGG 1159 Outtro MGG Monthly Giveaway Bandwidth Provided by CacheFly Pilot Pete's Aviation Podcast: So There I Was (for Aviation Enthusiasts) The Debut Film Podcast – Adam's new podcast! Dave's Business Brain (for Entrepreneurs) and Gig Gab (for Working Musicians) Podcasts MGG Merch is Available! Mac Geek Gab iOS app Mac Geek Gab YouTube Page Mac Geek Gab Live Calendar This Week's MGG Premium Contributors MGG Apple Podcasts Reviews feedback@macgeekgab.com 224-888-GEEK Active MGG Sponsors and Coupon Codes List BackBeat Media Podcast Network
BUFFALO, NY — September 14, 2026 — A new #review was #published in Volume 18 of Aging on August 26, 2026, titled “Assessing mechanisms and evidence of a causal role for cellular senescence and somatic mutations in aging.” The review examines two biological processes strongly associated with aging—cellular senescence and somatic DNA mutations—and evaluates whether the evidence supports their causal contribution to age-related functional decline. The review was authored by Lucrezia A. Trastus and Fabrizio d'Adda di Fagagna from IFOM ETS – The AIRC Institute of Molecular Oncology in Milan, Italy. d'Adda di Fagagna is also affiliated with the Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (IGM-CNR) in Pavia, Italy. Both authors are corresponding authors. Aging involves many interconnected molecular and cellular changes, making it difficult to distinguish processes that actively drive deterioration from those that simply accompany it. Trastus and d'Adda di Fagagna assess cellular senescence and somatic mutations using necessity and sufficiency as key criteria for causal inference. For cellular senescence, the evidence for causality is comparatively strong. Senescent cells undergo stable proliferative arrest, which can impair tissue regeneration, particularly when stem cells are affected. Their influence can extend far beyond individual cells through the senescence-associated secretory phenotype (SASP), a complex secretory program that allows senescent cells to alter surrounding tissues and promote senescence in neighboring cells. Full press release - https://www.aging-us.com/news-room/evidence-for-cellular-senescence-as-a-driver-of-aging-stronger-than-for-somatic-mutations DOI - https://doi.org/10.18632/aging.206414 Corresponding authors - Lucrezia A. Trastus - lucrezia.trastus@ifom.eu, Fabrizio d'Adda di Fagagna - fabrizio.dadda@ifom.eu Abstract video - https://www.youtube.com/watch?v=XHTBAJHjRZU Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206414 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, cellular senescence, somatic mutations, DNA damage, SASP To learn more about the journal, please visit https://www.Aging-US.com and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
Megaloblast. Now there's a word you don't hear every day. The root -blast comes from the Greek blastos, meaning “germ” or “bud,” and is familiar from terms like blast cells—very young hematopoietic precursor cells. Megalo- comes from the Greek megas, meaning “large” or “great,” as in splenomegaly. So is a megaloblast simply a large, immature cell? Not quite. In this episode, we break down megaloblastic anemia: why it develops, what vitamin B12 and folate have to do with it, what you'll see on a CBC and peripheral smear, and how to recognize and treat the underlying problem. After listening to this AudioBrick, you should be able to: Explain the pathogenesis of megaloblastic anemia. Identify common causes of vitamin B12 and folate deficiency and distinguish their associated nonhematologic findings. Recognize the characteristic complete blood count findings seen in megaloblastic anemia. Describe and identify the characteristic morphologic changes in the peripheral blood and bone marrow. Explain the principles of treatment for megaloblastic anemia. You can also explore the original Megaloblastic Anemia Brick from our Hematology collection, available free here: https://usmle-rx.scholarrx.com/rx-bricks/brick/CP_HEM0022 Want to explore more Rx Bricks and USMLE-Rx resources? Start your free USMLE-Rx trial and get five full days of access to Rx360+, including Qmax, Rx Bricks, Flash Facts, and Express Videos. https://usmle-rx.com/free-trial/ After your trial ends, you can continue accessing over 150 free Rx Bricks, including the complete General Microbiology and Cellular and Molecular Biology collections. If you enjoyed this episode, we'd appreciate a review on Apple Podcasts: https://podcasts.apple.com/us/podcast/the-rx-bricks-podcast/id1530646481 Reviews help more medical students and future physicians discover the Rx Bricks Podcast. Follow USMLE-Rx: Facebook: https://www.facebook.com/usmlerx Instagram: https://www.instagram.com/usmlerx/ X: https://x.com/usmlerx Threads: https://www.threads.net/@usmlerx YouTube: https://www.youtube.com/USMLERX Blog: https://usmle-rx.com/blog-posts/
Full show notes: BenGreenfieldLife.com/jubilee In this episode, John Jubilee makes the case that almost everything you have been told about hydration is beside the point. His argument is that the water is not the problem, the cell is: that a membrane gets progressively harder to penetrate as you age, that your water and your supplements simply bounce off it, and that until you change the membrane itself, nothing else you do gets in. He arrived at that after a decade of doing everything right, a gallon of water a day and a thousand dollars a month in supplements, and still having high blood pressure and no cartilage left in either knee. You'll hear the question he asked every one of his doctors that none of them could answer, the $11,000 machine he bought in 1997 to answer it himself, and the Energized Health protocol he built out of it. You'll also get the practical layer that costs nothing: the three steps he tells everyone to start with, the balls-of-your-feet walking trick and the soleus study behind it, his case for MSM, and why he refuses to recommend alkaline, structured, or reverse osmosis water. Then it turns personal, into cellular trauma, the ACE study, and why he believes a flawless diet still leaves something unaddressed. Mention Ben's name on your free breakthrough call with Energized Health for 40% off the 88-day program. Episode Sponsors: BIOptimizers Magnesium Breakthrough: Most magnesium supplements give you one or two forms. Magnesium Breakthrough gives you all seven, in the ratios your body actually uses, so you get better sleep, calmer nerves, and steadier energy. Go to bioptimizers.com/ben and use code BEN15 for 15% off any order. Dr. Murray ThymoQuin®: Black seed oil has been used for thousands of years, and ThymoQuin® is the most concentrated, highest-quality form of it available. It supports your immune system, your metabolism, and healthy inflammation levels. Visit doctormurray.com/ben and use code BEN25 for 25% off. ULTRA: A clean, functional performance drink with no artificial sweeteners, no seed oils, and no junk. Get it at bengreenfieldlife.com/ultra or takeultra.com and use code BENGREENFIELD for 15% off. Our Place: Nontoxic, PFAS-free cookware that replaces the whole cabinet with a few pieces you'll actually use. Go to fromourplace.com/ben and use code BEN for 10% off sitewide. Quantum Upgrade: Boost your cellular energy, wherever you are, with a field that works on you, your home, and even your car. Get a 15-day free trial at quantumupgrade.io with code BEN15.See omnystudio.com/listener for privacy information.
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Cellular health is at the foundation of vitality and longevity – because when you improve the health of your cells, you also reduce inflammation and target the root causes of many chronic illnesses. But how exactly do you improve the health your cells? On today's show, you're going to learn some fascinating insights about cellular health and how to give your body the inputs it needs for true strength and resilience. On this episode of The Model Health Show, our guest is leading functional medicine physician and author, Dr. Will Cole. His new book, Heal Your Cells, co-authored by Dr. Josh Axe, provides a proven plan to reverse cellular aging. In this interview, you're going to hear the latest research on organ aging, what toxic aging is, and the three hidden threats to your cellular health. Cellular health is not only the key to longevity, but also faster healing, optimal energy, and looking and feeling better. If you're ready to improve the health of your cells, this interview with Dr. Will Cole is going to empower you to take control of your health in a realistic, proven way. So click play and enjoy the show! In this episode you'll discover: The latest science on premature organ aging. (8:26) What cell ex-differentiation is. (12:15) The three hidden threats to your cellular health. (16:05) What biotoxins are. (20:44) A conversation on personalized medicine. (28:54) The bioindividuality of anxiety and depression. (38:05) Why you need to understand optimal vs. normal levels on lab work. (41:28) How to take a realistic approach to reducing your exposure to toxins. (41:52) What it means to support your body's natural detox pathways. (51:01) The benefits of xenohormetic foods. (53:05) Specific micronutrients that can support healthy aging. (56:55) How to reverse cellular aging. (1:02:40) Items mentioned in this episode include: Piquelife.com/model - Doctor-approved, cutting-edge solutions for your head-to-toe health and beauty transformation. Get exclusive savings on bundles & subscriptions. Paleovalley.com/model - Reclaim vibrant health with nutritional food and supplements that prioritize nutrient density and get 15% off your order. Heal Your Cells by Dr. Will Cole and Dr. Josh Axe - Get your copy of the new book! Connect with Dr. Will Cole Website / Facebook / Instagram / X Be sure you are subscribed to this podcast to automatically receive your episodes: Apple Podcasts Spotify Soundcloud Pandora YouTube This episode of The Model Health Show is brought to you by Pique and Paleovalley. Elevate your daily ritual with cutting-edge, doctor-approved teas designed to support your metabolism, skin, and overall vitality. Unlock exclusive savings on bundles and subscriptions at piquelife.com/model. If you're serious about real health, it starts with real nutrition. Paleovalley delivers nutrient-dense foods and supplements designed to help you feel stronger, more energized, and fully alive. Get 15% off your order at paleovalley.com/model.
BUFFALO, NY — September 9, 2026 — A new #research paper was #published in Volume 18 of Aging on August 13, 2026, titled “Protective effects of three herbal extracts on mitochondrial dysfunction in VPS13C-knockdown SH-SY5Y cells: implications for Parkinson's disease.” The study was led by co-first authors Yih-Ru Wu and Chih-Hsin Lin from the Chang Gung Memorial Hospital, Chang Gung University College of Medicine in Taoyuan, Taiwan, and Pei-Syuan Huang from the School of Life Science at National Taiwan Normal University in Taipei, Taiwan. Corresponding authors I-Cheng Chen and Guey-Jen Lee-Chen are from the School of Life Science at National Taiwan Normal University. The paper identifies Wu, Lin, and Huang as equal contributors. Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized primarily by dysfunction and loss of dopaminergic neurons in the substantia nigra. Although its causes are complex, mitochondrial dysfunction and oxidative stress are important biological processes implicated in both sporadic and inherited forms of the disease. The researchers focused on VPS13C, also known as PARK23, a gene associated with a rare autosomal recessive form of early-onset parkinsonism. Loss of VPS13C function has previously been linked to impaired mitochondrial function. The study investigated three extracts used in traditional Chinese medicine: Uncaria rhynchophylla (UR), Gardenia jasminoides (GJ), and Scutellaria baicalensis (SB). Previous experimental studies have reported neuroprotective effects from these plants or their bioactive constituents in models relevant to PD. The researchers examined whether the extracts could protect cells against mitochondrial dysfunction associated with reduced VPS13C expression. Chemical analyses identified several potentially bioactive constituents in the extracts. UR contained rhynchophylline and isorhynchophylline; GJ contained geniposide and crocin; and SB contained several flavonoids, including baicalin, wogonoside, baicalein, wogonin, and oroxylin A. Across the concentrations initially tested, the three extracts maintained greater than 90% viability in SH-SY5Y cells after 24 hours, indicating low cytotoxicity under these experimental conditions. Full press release - https://www.aging-us.com/news-room/three-herbal-extracts-protect-mitochondrial-function-in-a-cellular-model-of-parkinsons-disease DOI - https://doi.org/10.18632/aging.206409 Corresponding authors - I-Cheng Chen - ichen@ntnu.edu.tw, Guey-Jen Lee-Chen - t43019@ntnu.edu.tw Abstract video - https://www.youtube.com/watch?v=kM8hO89d_9k Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206409 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, Parkinson's disease, traditional Chinese medicine, VPS13C knockdown, mitochondrial dysfunction, oxidative stress To learn more about the journal, please visit https://www.Aging-US.com and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
Send us Fan MailSend us Fan MailIn this enlightening episode of Living the Dream with Curveball, we are joined by John Jubilee, co-founder of Energized Health, and his wife Chelsea. With over 25 years of experience, John shares his transformative journey from struggling with health and weight issues to discovering the power of intracellular hydration. He reveals how understanding cellular structure can unlock remarkable health benefits, allowing individuals to achieve lasting energy and vitality.John recounts his personal struggles with weight and health, including a pivotal moment that led him to research the science behind hydration and cellular health. He explains the difference between simply drinking water and achieving true intracellular hydration, emphasizing how this knowledge has helped thousands reverse various health challenges.Listeners will learn about:- The concept of intracellular hydration and its significance for overall health- John's 88-day protocol that helped him regain his health and vitality- Real-life success stories, including those of skeptics and medical professionals- The importance of sustainable health practices over temporary diets- Insights on aging and how to maintain strength and cognition as we grow olderJoin us for a thought-provoking discussion that will inspire you to rethink your approach to health and wellness. For more information about John and Chelsea Jubilee, and to learn more about their work at Energized Health, visit energizedhealth.comSupport the show
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Your body does its deepest repair work while you sleep. Directed at the cells that defend you, these affirmations invite immune strength, steady energy, and resilience to build overnight. Unwind now with our positive sleep affirmations podcast. Our soothing affirmations relax the mind and prepare the body for rest. Hit play, and drift into Good Sleep... Listen to more positive sleep affirmations by subscribing to the audio podcast in your favorite podcast app: Apple Podcasts: https://podcasts.apple.com/us/podcast/good-sleep-positive-affirmations/id1704608129 Spotify: https://open.spotify.com/show/3OuJvYoprqh7nPK44ZsdKE And start your morning with Optimal Living Daily! Apple Podcasts: https://podcasts.apple.com/us/podcast/optimal-living-daily-mental-health-motivation/id1067688314 Spotify: https://open.spotify.com/show/1hygb4nGhNhlLn4pBnN00j?si=ca60dcfd758b44b4 Learn more about your ad choices. Visit megaphone.fm/adchoices
The latest In Touch With iOS with Dave he is joined by Chuck Joiner, Jeff Gamet, Eric Bolden, Marty Jencius, Guy Serle. This week, the panel discusses John Ternus taking over as Apple CEO, Tim Cook's farewell, and the executive changes marking a new era at Apple. We cover the latest iOS 27, visionOS 27, macOS 27, watchOS 27, and tvOS 27 betas, plus strong AI-driven demand for Mac mini and Mac Studio and changes to Intel Mac support. Other topics include the Lake America mapping controversy, a useful Control Center Shortcut, Storm Radar bringing weather and navigation to CarPlay, Apple TV and Apple One price increases, older Macs becoming obsolete, and this week's Things We Found. The show notes are at InTouchwithiOS.com Direct Link to Audio Links to our Show Give us a review on Apple Podcasts! CLICK HERE we would really appreciate it! Click this link Buy me a Coffee to support the show we would really appreciate it. intouchwithios.com/coffee Another way to support the show is to become a Patreon member patreon.com/intouchwithios Website: In Touch With iOS YouTube Channel In Touch with iOS Magazine on Flipboard Facebook Page BlueSky Mastodon X Instagram Threads Topics and Links Summary This week, Dave is joined by Jill McKinley, Chuck Joiner, Jeff Gamet, Eric Bolden, Marty Jencius, and Guy Serle for a packed episode that begins with a major changing of the guard at Apple. Tim Cook has wrapped up his final day as CEO and moves into the executive chairman role as John Ternus officially takes over. The panel discusses Cook's farewell message, Ternus's first memo to Apple employees, what his hardware-engineering background could mean for Apple's future, and the wider executive changes accompanying the transition, including Phil Schiller scaling back his responsibilities. The crew also covers the latest Apple beta releases, including visionOS 27 beta 8, iOS and iPadOS 27 developer beta 8 and public beta 6, watchOS 27 beta 8, tvOS 27 beta 8, and macOS 27 beta 8. They look at the new iPhone Handoff capability in iOS 27, unexpectedly strong demand for Mac mini and Mac Studio for AI workloads, and Apple giving Mac App Store developers the option to drop Intel support. Other topics include the unusual Lake Ontario/Lake America mapping controversy involving Apple Maps, Google Maps, and MapQuest; a handy Shortcut for jumping directly to the current app's Settings from Control Center; and Storm Radar bringing route-aware weather, alerts, and navigation to CarPlay. In the news, Qualcomm is raising chip prices, several older Macs have moved onto Apple's obsolete-products list, Apple has been inducted into the Brand Hall of Fame, and Apple TV and the Apple One Individual plan are getting more expensive. Plus, Dave's Things We Found pick is the E-Rhino 165W four-port GaN USB-C charger Opening Segment Apple Transition: Tim Cook's Legacy and the John Ternus Era As of September 1, Apple has officially transitioned to a new leadership structure with John Ternus stepping in as CEO and Tim Cook assuming the role of Executive Chairman. This major shift includes Cook's final reflections, Ternus's initial vision for the company, and several notable executive reassignments accompanying the change. Tim Cook's departure from the CEO role On his final day as CEO, August 31, Cook shared an emotional message with Apple staff, expressing deep gratitude and characterizing his leadership years as a singular honor. Cook will continue to provide guidance in his new capacity as Executive Chairman. 9to5Mac - Tim Cook's full memo to employees on his last day as CEO (Aug. 31, 2026) John Ternus's first address as CEO During his first official day, Ternus acknowledged Cook's mentorship and emphasized his confidence in the current workforce. His message highlighted the upcoming September 9 launch and future product roadmaps, suggesting a focus on continuity while the panel analyzes his specific leadership style. 9to5Mac - Read new Apple CEO John Ternus's full memo to employees (Sept. 1, 2026) Apple Leadership Broad executive reshuffling Reporting indicates that the transition involves several high-level moves. Former CFO Luca Maestri has concluded his Corporate Services tenure, with Kevan Parekh assuming those duties. Adrian Perica is no longer appearing on the leadership roster, while Laura Legros has rejoined Apple in a strategic capacity supporting Ternus. 9to5Mac - John Ternus's first day as Apple CEO: Here's the latest (Sept. 1, 2026) Phil Schiller steps back Schiller has officially shifted his focus away from the App Store and product events, though he maintains his status as an Apple Fellow. Eddy Cue will now oversee the App Store with Carson Oliver managing daily operations, while Nola Weinstein takes the lead on events. This raises questions about how much of the senior hierarchy is being restructured at once. MacRumors - Apple's Phil Schiller Scales Back Role as John Ternus Era Begins (Aug. 31, 2026) Topics and Links In Touch With Vision Pro this week visionOS 27 beta 8 Apple released visionOS 27 developer beta 8 on August 31. Apple Developer lists build 24M5361a. This is a developer beta, not a final release. MacRumors - Apple Seeds Eighth visionOS 27 Beta to Developers (Aug. 31, 2026) Apple Developer - visionOS 27 release notes Apple Vision Pro was just used in a first-of-its-kind surgery Beta this week iOS 27 and iPadOS 27: developer beta 8 and public beta 6 Apple released iOS 27 and iPadOS 27 developer beta 8 on August 31, build 24A5430a. Later that day Apple released public beta 6 for iOS 27 and iPadOS 27. MacRumors reported no notable new features in the day's developer builds as the cycle approaches release. MacRumors - iOS 27/iPadOS 27 developer beta 8 (Aug. 31, 2026) MacRumors - iOS/iPadOS 27 public beta 6 (Aug. 31, 2026) Apple Developer - iOS & iPadOS 27 release notes watchOS 27 beta 8 Apple released watchOS 27 developer beta 8 on August 31. Apple Developer lists build 24R5360a. MacRumors - watchOS 27 beta 8 (Aug. 31, 2026) watchOS 27 Beta 8 Release Notes | Apple Developer Documentation tvOS 27 beta 8 Apple released tvOS 27 developer beta 8 on August 31. Apple Developer lists build 24J5360a. MacRumors - tvOS 27 beta 8 (Aug. 31, 2026) tvOS 27 Beta 8 Release Notes | Apple Developer Documentation iOS 27's new iPhone Handoff feature iOS 27 feature that can switch between two iPhones using the same phone number. Setup appears under Cellular, with one iPhone designated as the main device and the other as a companion. Carrier support appears to be required, so availability still needs confirmation when iOS 27 ships. MacRumors - iOS 27 Introduces New 'iPhone Handoff' Feature (Sept. 2, 2026) In Touch With Mac this week macOS 27 Golden Gate beta 8 Apple released macOS 27 developer beta 8 on August 31. Apple Developer lists build 26A5425a. The Mac beta stays in the Mac section rather than Beta this week. MacRumors - macOS 27 beta 8 (Aug. 31, 2026) Apple Developer - macOS 27 release notes AI demand reportedly caught Apple off guard on Mac mini and Mac Studio MacRumors, citing The Information, reports that unusually strong enterprise demand for Macs used for AI workloads helped drive Apple's unusually early Mac mini and Mac Studio launch. The report says high-end configurations have faced supply pressure amid the broader memory shortage. MacRumors - Apple Caught Off Guard by AI Demand for Mac Mini and Mac Studio (Aug. 30, 2026) Mac App Store apps can now drop Intel Mac support Apple told developers that universal Mac App Store apps requiring macOS 13 or later can remove the x86_64 architecture. Intel users can keep using the last compatible version, but developers can stop shipping updates to Intel Macs. MacRumors - Mac App Store Apps Can Now Drop Support for Intel Macs (Sept. 1, 2026) Other Topics In Touch with Jeff Gamet's Blog Will AI Ever Attain AGI Level? Nope Anthropic has upgraded Claude's computer-use capability on Mac so tasks can run in the background Anthropic upgrades Claude's computer use to run in the background on Mac Tip: open the current app's Settings from Control Center A Shortcut shared by Quinn Nelson can be assigned to Control Center's Run Shortcut control or the Action button, providing a fast path to the Settings page for the app currently in use. MacRumors How-To - Open the Current App's Settings From Control Center (Sept. 2, 2026) App: Storm Radar comes to CarPlay The Weather Channel's Storm Radar 4.0.19 added a dedicated CarPlay app with map/satellite views, weather layers, destination conditions, navigation, route weather alerts, and automatic rerouting. This is standard CarPlay, not CarPlay Ultra. 9to5Mac - Apple CarPlay just added a major weather app (Aug. 30, 2026) News Qualcomm raises chip prices Qualcomm said chip prices would rise by double digits for chips shipped after September 1, citing higher supplier costs. The Apple angle is the continuing importance of component pricing as Apple shifts more modem work in-house. MacRumors - Qualcomm Raising Chip Prices Starting Tomorrow (Aug. 31, 2026) Three more Macs become obsolete Apple moved the 2018 Retina MacBook Air, 13-inch 2018 MacBook Pro with four Thunderbolt 3 ports, and 13-inch 2017 MacBook Pro with two Thunderbolt 3 ports to its obsolete list. Obsolete products are generally no longer eligible for Apple hardware service, although Apple's laptop battery-only repair policy can extend longer in some cases. MacRumors - Apple Adds Three More Macs to Obsolete Products List (Aug. 31, 2026) Apple enters the Brand Hall of Fame The One Club for Creativity selected Apple as the first brand inducted into its newly established Brand Hall of Fame, recognizing the company's history of influential advertising. MacRumors - Apple Inducted Into 'Brand Hall of Fame' for Iconic Ads (Aug. 31, 2026) This week's "Things we found" Dave: mfish E-RHINO 165W 4-Port GaN USB-C Charger. The manufacturer lists four USB-C ports, up to 165W combined dual-port output, up to 140W from C1 or C2 individually, and a display showing output and temperature. Current direct-site pricing should be checked at recording time. Amazon mfish direct product page Eric: OWC drive dock A good way to swap between several old drives while waiting for drive prices to drop. https://www.owc.com/solutions/drive-dock https://amzn.to/4cviDHk Jeff: Riff Calendar It's a calendar app that lets you zoom in for a more granular look at your schedule instead of the traditional day, week, and month views. It's in beta for iPhone now. https://riffcalendar.com/ Chuck: ORICO External Hard Drive Case for 3.5 Inch HDD/SSD 5 Packs Portable Hard Drive Carrying Protective Storage Box Anti-Static and Shockproof https://amzn.to/4qWI6PZ 57 Nut and Bolt Thread Checker with 21 Standard &17 Metric &19 Drill Gauges https://amzn.to/3UAhhVB Marty: Chad Powers: on Hulu Season 1 Trailer: https://www.youtube.com/watch?v=_nFZMD8FMM0 Season 2 Trailer: https://www.youtube.com/watch?v=-8B59O_18Dc Ted Lasso Party Game: https://www.amazon.com/Funko-63413-Ted-Lasso-Game/dp/B09QV34247 Announcements Macstock X wrapped up for 2026 what a great event! Stay tuned for the Digital pass coming soon Digital Pass | Macstock Conference & Expo Our Host Dave Ginsburg is an IT professional supporting Mac, iOS and Windows users and shares his wealth of knowledge of iPhone, iPad, Apple Watch, Apple TV and related technologies. Visit the YouTube channel https://youtube.com/intouchwithios follow him on Mastodon @daveginsburg, , BlueSky @daveginsburg and the show @intouchwithios Our Co-Hosts Jeff Gamet is a podcaster, technology blogger, artist, and author. Previously, he was The Mac Observer's managing editor, and Smile's TextExpander Evangelist. You can find him on his blog Jeff Gamet - Mastadon @jgamet Pixelfed @jgamet@pixelfed.social and Bluesky @jgamet.bsky.social Podcasts The Context Machine Podcast Retro Rewatch Retro Rewatch His YouTube channel https://youtube.com/jgamet Buy his art! Jeff Gamet Art Marty Jencius, Ph.D., is a professor of counselor education at Kent State University, where he researches, writes, and trains about using technology in teaching and mental health practice. His podcasts include Vision Pro Files, The Tech Savvy Professor and Circular Firing Squad Podcast. Find him at jencius@mastodon.social https://thepodtalk.net Eric Bolden is into macOS, plants, sci-fi, food, and is a rural internet supporter. You can connect with him by email at eabolden@mac.com, on Mastodon at @eabolden@techhub.social, on his blog, Trending At Work, and as co-host on The Vision ProFiles podcast. Jill McKinley works in enterprise software, server administration, and IT. A lifelong tech enthusiast, she started her career with Windows but is now an avid Apple fan. Beyond technology, she shares her insights on ai, nature, faith, and personal growth through her podcasts. Her content on YouTube at @smallstepswithai and follow her on X @NorthwoodsJill. Find all her work at http://jillfromthenorthwoods.com Chuck Joiner is the host of MacVoices and hosts video podcasts with influential members of the Apple community. Make sure to visit macvoices.com and subscribe to his podcast. You can follow him on Twitter @chuckjoiner and join his MacVoices Facebook group.
Your body does its deepest repair work while you sleep. Directed at the cells that defend you, these affirmations invite immune strength, steady energy, and resilience to build overnight. Unwind now with our positive sleep affirmations podcast. Our soothing affirmations relax the mind and prepare the body for rest. Hit play, and drift into Good Sleep... Listen to more positive sleep affirmations by subscribing to the audio podcast in your favorite podcast app: Apple Podcasts: https://podcasts.apple.com/us/podcast/good-sleep-positive-affirmations/id1704608129 Spotify: https://open.spotify.com/show/3OuJvYoprqh7nPK44ZsdKE And start your morning with Optimal Living Daily! Apple Podcasts: https://podcasts.apple.com/us/podcast/optimal-living-daily-mental-health-motivation/id1067688314 Spotify: https://open.spotify.com/show/1hygb4nGhNhlLn4pBnN00j?si=ca60dcfd758b44b4 Learn more about your ad choices. Visit megaphone.fm/adchoices
Are you fascinated by the molecular science of aging and senescence? In this episode of Beauty Bytes, I am joined by Dr. Frederick Beddingfield III, the CEO of Rubedo Life Sciences, a physician-scientist, and a former senior leader at Allergan. We focus on the cutting edge of longevity and how Rubedo is developing adaptive senotherapeutics to reverse cellular aging and extend healthspan. Dr. Beddingfield explains the science behind their lead drug, RLS 1496, which targets the enzyme glutathione peroxidase 4 (GPX4) to regulate ferroptosis, an iron-dependent cell death pathway. We discuss how this drug not only eliminates toxic senescent cells but also acts as a "redox reset" for aged cells, reducing their biological age by improving mitochondrial function and autophagy. We also explore their groundbreaking human clinical trials, which demonstrated a 50% reduction in precancerous actinic keratoses in just four weeks without causing skin irritation. Plus, Dr. Beddingfield shares his personal biohacking stack, including low-dose rapamycin, fisetin, and quercetin. Guest Information:Dr. Frederick Beddingfield III is the CEO of Rubedo Life Sciences. You can learn more about their clinical trials at rubedolifesciences.com or follow him on Instagram and LinkedIn at @FrederickBeddingfield.
What if chronic disease isn't primarily an organ problem, but a cellular one?In this episode, Dr. Will Cole joins Justin Harris to explore the emerging science of cellular health and longevity. Dr. Will Cole is a leading functional medicine practitioner, New York Times bestselling author, and host of The Art of Being Well podcast. They sit down to discuss his latest book, Heal Your Cells: Reversing the Irreversible, co-authored with Dr. Josh Axe. Together, they explore why cellular dysfunction may be the true root of chronic disease, how lifestyle and environment shape our health trajectory, and why longevity is about more than simply extending lifespan.If you wish to learn more from Dr. Will Cole, you can do so through the following links:Visit his website at https://drwillcole.com/ Podcast: The Art of Being WellPre-order Dr. Cole's book now at https://thehealthinstitute.com/products/heal-your-cells and get bonuses before it releases on September 8th!______________________________________________________Keep yourself up to date on The DNA Talks Podcast! Follow our socials below:The DNA Talks Podcast Instagram: @dnatalkspodcastThe DNA Company Instagram: @thednacoThe DNA Company's Official Tiktok Account: @thednaco3Justin's Instagram Account: @justinharrisofficialMedical Disclaimer: The information provided in this communication is for general informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read here. If you think you may have a medical emergency, call your doctor or 911 immediately.
In this episode, Dr. David Jockers is joined by his longtime friend Dr. Josh Axe, co-founder and chief visionary officer of Ancient Nutrition, founder of draxe.com, and founder of The Health Institute, for a deep dive into cellular longevity. You will learn why some organs age faster than others, what's really happening inside your cell membranes and mitochondria as you get older, and which foods, from super berries and pomegranates to organ meats, healthy fats, fermented foods, and longevity mushrooms, do the most to slow that process down. Dr. Axe and Dr. Jockers also break down his top longevity supplements, including vitamin D, soil-based probiotics, omega-3s, magnesium, and NAD/NMN, why quality matters so much more than quantity when it comes to supplements, and the surprising role of the gut microbiome, bee products, and daily herbal tea in living a longer, more vibrant life. In This Episode: 00:00 Berry Powders Routine 00:14 Longevity Podcast Intro 04:02 What Is Cellular Longevity 04:52 Aging Organs and Cells 06:52 Cell Membranes and Mitochondria 09:26 Foods to Live Past 100 09:53 Super Berries for Longevity 13:18 Pomegranate and Urolithin A 17:24 Akkermansia and Ellagic Acid 19:00 Vegetables for Detox and Heart 20:35 Organ Meats and Methylation 23:44 Protein and Like Supports Like 25:37 Omega 3s and Healthy Fats 28:59 Oil Quality Over Smoke Point 29:18 Choosing High Polyphenol Olive Oil 30:19 Healthy Fats For Longevity 30:52 Fermented Foods And Gut Health 32:30 Longevity Mushrooms Explained 33:58 Longevity Foods Recap 34:42 Top Supplements Vitamin D 40:13 Probiotics Omega 3 And Quality 43:32 Avoiding Bad Supplements Calcium 44:21 NAD NMN And Supplement Impact 46:54 Magnesium Adaptogens And Green Tea 48:44 Bee Products And Venom Therapy 51:23 Herbal Tea Daily Ritual 52:28 Where To Find Dr Josh Axe 53:50 Final Thanks And Sign Off This podcast is sponsored by Paleo Valley's Turmeric Complex, a whole-food organic turmeric formula (not just isolated curcumin) blended with coconut oil and black pepper for absorption, plus ginger, rosemary, and cloves for extra anti-inflammatory and brain-support benefits. Go to paleovalley.com/jockers for 15% off your order. Bon Charge's Red Light Toothbrush combines the most researched red and near-infrared wavelengths (660 and 830 nanometers) with sonic power to support circulation, manage gingival inflammation, and aid recovery after dental procedures, all in your everyday brushing routine. It's HSA/FSA eligible, travel-ready, and low EMF. Go to boncharge.com and use code DRJOCKERS for 15% off, with free shipping and a 12-month warranty. Inflammaging, the chronic low-grade inflammation that accelerates aging, often shows up first in the skin. Holistic Goddess Frankincense Castor Oil roll-on uses organic, cold-pressed, hexane-free castor oil and organic frankincense to deeply moisturize and soften the look of fine lines, with a cooling rose quartz applicator. Go to holisticgoddess.com and use code DRJOCKERS for free shipping. Busy, stressed, low-carb, or training hard? You're likely losing more electrolytes than you realize. ReLyte from Redmond is made with Redmond's Real Salt, an ancient, unrefined Utah sea salt with trace minerals, plus two types of magnesium for better absorption, no sugar, and no artificial ingredients. Go to redmond.life/doctorjockers and use code JOCKERS for 15% off. "Pomegranates are right up there with goji berries as top superfoods for longevity." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Visit paleovalley.com/jockers to get 15% off Paleo Valley's Turmeric Complex and other products Visit boncharge.com and use code DRJOCKERS for 15% off the Red Light Toothbrush, with free shipping and a 12-month warranty Visit holisticgoddess.com and use code DRJOCKERS for free shipping on the Frankincense Castor Oil roll-on Visit redmond.life/doctorjockers and use code JOCKERS for 15% off ReLyte electrolytes Connect with Dr. Josh Axe: Website – https://draxe.com/ Instagram – https://www.instagram.com/drjoshaxe/ Book – https://amzn.to/4glff4y Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
A protein has no idea where it's going. So how does it end up exactly where it needs to be, inside the nucleus, in the mitochondria, or shipped out of the cell entirely?In this episode of the Jack Westin MCAT Podcast, Mike and Molly pick up where cell biology left off. After breaking down individual organelles in the last episode, they now tackle the mechanism that connects them all: the endomembrane system and the secretory pathway. This is the process by which proteins get tagged, routed, folded, modified, and shipped to their final destination, and it's one of the most overlooked-yet-testable systems on the MCAT.Get started with our resources!
Tonight on America At Night with McGraw Milhaven, Augustus Doricko, environmental entrepreneur and founder and CEO of Rainmaker, discusses the company's groundbreaking cloud-seeding technology, including a recent Alaska test that reportedly generated millions of gallons of water in just hours, and what this technology could mean for drought and water security. Dr. Kevan Shokat, Professor of Cellular and Molecular Pharmacology at UCSF and Howard Hughes Medical Institute Investigator, discusses the FDA's approval of a promising new drug for pancreatic cancer and why the treatment could represent an important development for patients facing one of the deadliest forms of cancer. Hollywood legend John Goodman joins McGraw to talk about his new film Digger, starring alongside Tom Cruise, and his experience working on the highly anticipated movie. Plus, Bill Clevlen, founder of BillOnTheRoad.com, returns with another edition of the weekly Bill on the Road travel segment. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Your annual physical came back "normal," so why do you still feel foggy, tired, and stuck? Dr. Adrijana Kekic says your biology has probably been drifting for years before any standard test notices. Former Mayo Clinic pharmacogenomics specialist and Futurome founder Dr. Adrijana Kekic reveals what a standard 30 to 100 marker panel misses, how multi-omics testing catches metabolic drift early, and why women age differently after 40. After a preventable pulmonary embolism nearly killed her, she rebuilt her own health and now maps cellular aging for people who look fine on paper. Meet our guest Dr. Adrijana Kekic is a pharmacist and nutritionist trained in genetics, one of the first pharmacogenomics clinical specialists at Mayo Clinic and winner of its 2023 Innovation Award. She founded Futurome, a precision health intelligence company that reads thousands of biomarkers to map cellular aging, with a special focus on female biology. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Standard panels lean on late markers; fasting insulin and HOMA-IR flag metabolic trouble years earlier. Multi-omics testing reads thousands of markers across genomics, proteomics, metabolomics, and microbiome. Cellular aging spikes around 40 and 60, the windows where personalization pays off most. The highest mitochondrial density in women sits in the ovaries; decline can surface there before any blood test. Perimenopause is estrogen swinging up and down, not just falling; it hides on standard labs. Women make about 50% less gut serotonin than men, so fasting protocols should differ by sex. Foundation first: sleep, magnesium, vitamin D, movement, and a CGM before advanced interventions. Episode highlights 0:00 Normal labs, hidden aging 6:09 What standard bloodwork misses 18:24 The two aging cliffs at 40 & 60 25:33 The perimenopause you don't notice 30:27 The ICU wake-up call 40:40 Foundation before shiny objects 46:18 Why men & women differ Links Watch it on YouTube: https://youtu.be/1P-vuKmzvtw Full episode show notes: https://outliyr.com/275 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick
Can a trail camera do more than just capture photos? Brian Dunn of Wise Eye Technology joins the show to talk about how trail cameras have transformed deer scouting and what hunters can do to get more useful information from every camera they hang. We cover camera placement, patterning mature bucks, minimizing hunting pressure, common scouting mistakes, and how AI is shaping the future of trail camera technology. Whether you're getting ready for deer season or looking to improve your scouting strategy, this episode is packed with practical tips that can help you make better decisions in the woods. In this episode: Best trail camera placement strategies How to pattern mature bucks Common trail camera mistakes Cellular trail cameras and hunting pressure The future of AI in deer scouting
Unbreakable: A Woman's Guide to Aging with Power A clear, science-backed roadmap to building strength, supporting your body, and taking control of how you age. Get your copy: https://www.theunbreakablelifestyle.com/unbreakable-book Zombie movies are fun but Zombie cells are not. They are inside your body that have reached the end of their natural lifespan and simply refuse to die. Today I break down the fourth major time bomb of aging: cellular senescence, and how these "zombie cells" quietly accelerate the way you age. These damaged cells actively poison the healthy cells around them, releasing signals that drive chronic inflammation and pull neighboring cells into the same broken state. This accumulation is directly linked to neurodegenerative disease, cardiovascular disease, and cancer, and for women, it speeds up dramatically as estrogen declines through the menopausal transition. The good news is that you have more control than you think. I walk you through exactly how to activate your body's cellular cleanup crew through movement, hormonal optimization, and precision nutrition, so you can stop surrendering to frailty and start building longevity by design. What we cover: - Cellular senescence: what zombie cells are and why they matter - Macroautophagy: your body's natural cellular cleanup process - Aging and cleanup decline: why senescent cells accumulate over time - Noxious cytokines: how zombie cells spread chronic inflammation - Disease links: senescence, neurodegeneration, cardiovascular disease, and cancer - Estrogen and menopause: why senescence rises during the transition - Aerobic exercise: forcing cellular cleanup through movement - Muscle health: your master regulator of cellular hygiene - Senolytic nutrition: fisetin, quercetin, and resveratrol - Hormonal optimization: defending against cellular senescence
Aging is not merely a slow decline but a biological process we can influence by managing our internal cellular health. Host Zach Gurick connects with Dr. Nayan Patel, the renowned longevity pharmacist and author of The Glutathione Revolution, to uncover how our bodies use glutathione to neutralize the cellular damage caused by oxidative stress. Dr. Patel explains his breakthrough delivery technology that finally makes this master antioxidant bioavailable at the cellular level. They discuss why our natural production of glutathione plateaus as we age and how simple, consistent lifestyle habits can restore our body's innate ability to detoxify and regenerate. Listeners will gain a practical roadmap for reducing inflammation, boosting energy, and reclaiming their vitality. This conversation offers a hopeful, science-backed perspective on what is possible for our healthspan.The information presented in Fully Alive is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before making changes to your health regimen. Guests' opinions are their own and do not necessarily reflect those of the podcast host, production team, or sponsors.Love the show? Subscribe, rate, review, & share! https://www.shellpoint.org/podcast/
Your health isn't just about symptoms; it's about the very terrain of your cells. Dr. Jess Armine, with 50 years in healthcare, reveals how genetics, neuroendoimmunology, and mitochondrial function dictate your well-being, sharing his personal journey that led him to uncover these profound connections. TIMESTAMPS 00:00 – Introduction to Dr. Jess Armine 00:30 – Dr. Jess's 50-year journey in healthcare 01:30 – From EMT to critical care nurse to chiropractor 02:15 – Why traditional chiropractic felt limiting 02:30 – The personal crisis that reshaped his practice 03:00 – Diving deep into neurotransmitter balances 03:30 – Developing expertise in genetics and neuroendoimmunology 03:55 – The importance of mitochondrial function and cell membrane integrity LINKS
In this episode of Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon, I am joined by Dr. Koji Tanabe, a leading stem cell scientist, founder and CEO of iPeace, and one of the researchers behind the landmark development of human induced pluripotent stem cells, or iPSCs. Dr. Tanabe breaks down the science of Yamanaka factors and explains how mature cells can be reprogrammed into a younger, pluripotent state with the ability to develop into many different cell types. We explore how iPSC technology differs from traditional stem cells, PRP, exosomes, and other regenerative treatments, as well as why creating and quality-checking these cells outside the body may offer important advantages over attempting cellular reprogramming directly inside the body. Dr. Tanabe also shares how iPSC-derived cells are being explored in regenerative applications involving heart failure, Parkinson's disease, spinal cord injury, and other areas of medicine. We dive into the future of personalized cell banking, why he believes it may be beneficial to preserve cells while you are healthy, and how iPSC-derived factors, or iPSF, are being explored for skin rejuvenation, hair restoration, and systemic longevity treatments. The iPSF treatments discussed in this episode are currently available only in Japan and are not available in the United States at this time due to differences in regulatory standards. From cellular aging and DNA mutations to epigenetic clocks, regenerative medicine, and the difference between lifespan and healthspan, this conversation offers a fascinating look at how cellular reprogramming could change the way we approach aging, disease, and the future of personalized medicine.Clarification: During the discussion of iPSC-derived therapies for heart failure, the conversation referenced the possibility of creating patient-specific, autologous iPSC-derived cells. The currently approved application discussed in this episode is allogeneic, not autologous. Dr. Tanabe was referring to the potential for iPSC technology to be developed for personalized autologous applications.Guest Information: Dr. Koji Tanabe is a stem cell scientist and the founder and CEO of iPeace. He spent eight years conducting research at Kyoto University in Nobel laureate Dr. Shinya Yamanaka's laboratory and was the second author on the landmark 2007 paper describing the generation of human induced pluripotent stem cells. His work focuses on cellular reprogramming, regenerative medicine, personalized iPSC manufacturing, and the potential use of iPSC technology in longevity and future cell-based therapies. Check them out at: https://ipeace.com/en/ or @mypeace_ips.
Inside today's episode, I break down the research on how anger affects the body from the inside out including the acute cardiovascular events, the chronic inflammatory picture, and the emerging cellular aging data. I walk through the acute mechanism starting in the amygdala and running through the sympathetic nervous system, the adrenaline and noradrenaline release, the peripheral vasoconstriction and stickier blood that primes the platelets, and the plaque rupture cascade that explains the two-hour heart attack window and so much more.Topics discussed: - The Two-Hour Heart Attack Window After Anger- The Amygdala-to-Adrenaline Cascade- Plaque Rupture and Blood That's Primed to Clot- Why Anger Is Different From Fear Physiologically- Chronic Inflammation and Endothelial Dysfunction- The Meta-Analysis on Hostility and Heart Disease- What the Whitehall Cohort Data Shows---------- My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization www.metabolismschool.com---------- [Free] Metabolism School 101: The Video Serieshttp://www.metabolismschool.com/metabolism-101----------Subscribe to My Youtube Channel: https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1----------Grab a Copy of My New Book - Metabolism Made Simple---------- Stay Connected: Instagram: @sammillerscienceYoutube: SamMillerScience Facebook: The Nutrition Coaching Collaborative CommunityTikTok: @sammillerscience----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at operations@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."
In this episode, we're featuring MitoQ, a company whose research around antioxidant support for mitochondrial function has been of particular interest to me. I'm thrilled to welcome Dr. Siobhan Mitchell, the Chief Scientific Officer at MitoQ. Dr. Mitchell completed her PhD at SUNY Albany and a postdoctoral fellowship on brain aging at the University of Washington. She has held roles at multinational food companies, leading research on brain nutrition, metabolism, cardiovascular health, and weight loss. She has published clinical research demonstrating the effects of stress on women's heart health and the importance of nutrients such as polyphenols, omega-3s, probiotics, and amino acids for brain health, authored dozens of clinical studies and more than 80 papers, and given talks on nutritional neuroscience at conferences worldwide. She also holds eight patents for products related to aging, cognition, and mood. In today's conversation, Dr. Mitchell and I discuss mitochondrial physiology, energy, and dysfunction, exploring the impact of MitoQ and supplementation for supporting health. We examine research on menopause, how estrogen influences mitochondria, the roles of oxidative stress, antioxidants, and zombie cells, highlighting how mitochondria impact our cardiovascular health, the value of MitoQ in supporting vascular function in females, the importance of polyphenols and spices, and signs of mitochondrial dysfunction. This is a truly invaluable conversation- one you'll likely want to revisit. Stay tuned for today's informative discussion on supporting our mitochondria and reducing oxidative stress with MitoQ. IN THIS EPISODE, YOU WILL LEARN: How our mitochondrial function changes as we get older, and what those changes might look like How antioxidants protect the mitochondria from free radicals and oxidative stress The early signs of mitochondrial dysfunction How women who have damaged their mitochondria earlier in life can proactively support their mitochondria Why some oxidative stress may be beneficial and when it could become problematic How mitochondrial dysfunction impacts heart function, blood glucose regulation, insulin resistance, and metabolic syndrome What Dr. Mitchell recommends for women learning about mitochondrial support for the first time Dr. Mitchell shares the daily practices she uses to support her brain and metabolic health. How long you may need to take MitoQ before noticing improvements, and what those improvements might look like Bio: Dr. Siobhan Mitchell Siobhan Mitchell is the chief scientific officer of MitoQ. She completed her PhD at SUNY Albany and a post-doctoral fellowship on brain aging at the University of Washington. Siobhan has held roles at multinational food companies leading research on brain nutrition, metabolism, cardiovascular health and weight loss. Siobhan has published clinical research showing the effects of stress on women's heart health, and the importance of nutrients such as polyphenols, omega-3 oils, probiotics and amino acids for brain health. She has authored over a dozen clinical studies on best practices for weight management and prevention of chronic diseases during her time as senior director for Noom. Siobhan is passionate about the intersection of nutrition and lifestyle factors, such as exercise, sleep, and mental well-being, to extend health span. Siobhan has given talks on nutritional neuroscience at conferences all over the world. She's authored over 80 papers and holds eight patents for aging, cognition, and mood products. Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Siobhan Mitchell MitoQ The Mitochondrial Collaborative Research Programme (MCRP) Email Dr. Siobhan Mitchell: s.mitchell@mitocq.com
Welcome to another episode of
Episode Highlights With CarolineHer story with minerals and fertility and what she learned the tough wayThe long road to having her two kids and how her health suffered afterWhat makes fulvic and humic minerals different and why her job is to make these famous Why she considers these compounds the celebrities of mineral replenishmentA new way of thinking about the body and fuel Minerals are the fuel that's translated into energy in the body and the real consequences of being low in minerals What humic and fulvic actually are and the way that the earth stores energy for future use What changed for her when she replenished minerals at a cellular level The symptoms that can be connected to low minerals that you may not realize How mineral depletion relates to hormones, hair loss, fatigue, blood sugar and moreThe voltage first understanding of the body's energy We're meant to generate enough energy to run a light bulb and many of us aren't! How chronic issues are often connected to mineral depletion What plant-based minerals are and what makes them different The difference between fulvic and humic and why we need bothHumic (dark): microboost- nature's janitor. Fulvic- (clear): electrolyze (natures hydration)How to introduce these minerals the right way to support the bodyResources MentionedBEAM MineralsThe Mineral Reset book by Caroline AlanLMNTI talk often about the health benefits of salt and electrolytes and I am a big fan of LMNT canned drinks and packets. Go to drinklmnt.com/wellnessmana for a special offer.BONCHARGEI like so many of their products - from their red light products to their sauna blankets. Red light has been so helpful for me during my recovery from Hashimoto's. To find out more, go to boncharge.com/wellnessmama