Podcasts about series stem cell channel health

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Best podcasts about series stem cell channel health

Show all podcasts related to series stem cell channel health

Latest podcast episodes about series stem cell channel health

Winning the War on Cancer (Video)
Defining the Limits of Metabolic Flexibility of Squamous Cell Carcinoma with William Lowry - Sanford Stem Cell Symposium 2023

Winning the War on Cancer (Video)

Play Episode Listen Later Jun 5, 2025 42:31


William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]

Science (Video)
Defining the Limits of Metabolic Flexibility of Squamous Cell Carcinoma with William Lowry - Sanford Stem Cell Symposium 2023

Science (Video)

Play Episode Listen Later Jun 5, 2025 42:31


William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]

Health and Medicine (Video)
Defining the Limits of Metabolic Flexibility of Squamous Cell Carcinoma with William Lowry - Sanford Stem Cell Symposium 2023

Health and Medicine (Video)

Play Episode Listen Later Jun 5, 2025 42:31


William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]

University of California Audio Podcasts (Audio)
Defining the Limits of Metabolic Flexibility of Squamous Cell Carcinoma with William Lowry - Sanford Stem Cell Symposium 2023

University of California Audio Podcasts (Audio)

Play Episode Listen Later Jun 5, 2025 42:31


William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]

Health and Medicine (Audio)
Defining the Limits of Metabolic Flexibility of Squamous Cell Carcinoma with William Lowry - Sanford Stem Cell Symposium 2023

Health and Medicine (Audio)

Play Episode Listen Later Jun 5, 2025 42:31


William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]

Science (Audio)
Defining the Limits of Metabolic Flexibility of Squamous Cell Carcinoma with William Lowry - Sanford Stem Cell Symposium 2023

Science (Audio)

Play Episode Listen Later Jun 5, 2025 42:31


William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]

UC San Diego (Audio)
Defining the Limits of Metabolic Flexibility of Squamous Cell Carcinoma with William Lowry - Sanford Stem Cell Symposium 2023

UC San Diego (Audio)

Play Episode Listen Later Jun 5, 2025 42:31


William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]

Winning the War on Cancer (Audio)
Defining the Limits of Metabolic Flexibility of Squamous Cell Carcinoma with William Lowry - Sanford Stem Cell Symposium 2023

Winning the War on Cancer (Audio)

Play Episode Listen Later Jun 5, 2025 42:31


William Lowry, Ph.D., discusses manipulating metabolic pathways in hair follicle stem cells to inhibit tumorigenesis. By blocking glycolysis and glutamine lysis simultaneously, they observed tumor regression, highlighting the complex interplay between metabolism and cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39256]

Science (Video)
3rd Annual Global Astrobiotechnology Hub

Science (Video)

Play Episode Listen Later May 5, 2025 86:58


The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

Astronomy (Video)
3rd Annual Global Astrobiotechnology Hub

Astronomy (Video)

Play Episode Listen Later May 5, 2025 86:58


The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

Health and Medicine (Video)
3rd Annual Global Astrobiotechnology Hub

Health and Medicine (Video)

Play Episode Listen Later May 5, 2025 86:58


The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

University of California Audio Podcasts (Audio)
3rd Annual Global Astrobiotechnology Hub

University of California Audio Podcasts (Audio)

Play Episode Listen Later May 5, 2025 86:58


The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

Health and Medicine (Audio)
3rd Annual Global Astrobiotechnology Hub

Health and Medicine (Audio)

Play Episode Listen Later May 5, 2025 86:58


The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

Science (Audio)
3rd Annual Global Astrobiotechnology Hub

Science (Audio)

Play Episode Listen Later May 5, 2025 86:58


The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

Astronomy (Audio)
3rd Annual Global Astrobiotechnology Hub

Astronomy (Audio)

Play Episode Listen Later May 5, 2025 86:58


The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

UC San Diego (Audio)
3rd Annual Global Astrobiotechnology Hub

UC San Diego (Audio)

Play Episode Listen Later May 5, 2025 86:58


The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of conducting real-time research in space, the need for specialized astronaut-scientists, and the potential of space for groundbreaking experiments, such as organoid growth and in-space manufacturing. Experts underscore the importance of public access to scientific data and highlight the role of new media in engaging the public with space research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40389]

Science (Video)
Stem Cells Scientific Publishing - Sanford Stem Cell Symposium 2024

Science (Video)

Play Episode Listen Later Feb 18, 2025 58:38


Karen Christman, Sheila Chari, Stella Hurtley, and Robert Stephenson explore academic publishing in stem cell research, focusing on reproducibility, collaboration, and public communication. Editors from top journals discuss curating impactful research, sharing clinical trial data, and addressing challenges in scaling and standardizing therapies. They emphasize bridging silos, advancing precision regenerative medicine, and navigating open access publishing to responsibly propel the field forward. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39940]

Health and Medicine (Video)
Stem Cells Scientific Publishing - Sanford Stem Cell Symposium 2024

Health and Medicine (Video)

Play Episode Listen Later Feb 18, 2025 58:38


Karen Christman, Sheila Chari, Stella Hurtley, and Robert Stephenson explore academic publishing in stem cell research, focusing on reproducibility, collaboration, and public communication. Editors from top journals discuss curating impactful research, sharing clinical trial data, and addressing challenges in scaling and standardizing therapies. They emphasize bridging silos, advancing precision regenerative medicine, and navigating open access publishing to responsibly propel the field forward. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39940]

University of California Audio Podcasts (Audio)
Stem Cells Scientific Publishing - Sanford Stem Cell Symposium 2024

University of California Audio Podcasts (Audio)

Play Episode Listen Later Feb 18, 2025 58:38


Karen Christman, Sheila Chari, Stella Hurtley, and Robert Stephenson explore academic publishing in stem cell research, focusing on reproducibility, collaboration, and public communication. Editors from top journals discuss curating impactful research, sharing clinical trial data, and addressing challenges in scaling and standardizing therapies. They emphasize bridging silos, advancing precision regenerative medicine, and navigating open access publishing to responsibly propel the field forward. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39940]

Health and Medicine (Audio)
Stem Cells Scientific Publishing - Sanford Stem Cell Symposium 2024

Health and Medicine (Audio)

Play Episode Listen Later Feb 18, 2025 58:38


Karen Christman, Sheila Chari, Stella Hurtley, and Robert Stephenson explore academic publishing in stem cell research, focusing on reproducibility, collaboration, and public communication. Editors from top journals discuss curating impactful research, sharing clinical trial data, and addressing challenges in scaling and standardizing therapies. They emphasize bridging silos, advancing precision regenerative medicine, and navigating open access publishing to responsibly propel the field forward. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39940]

Science (Audio)
Stem Cells Scientific Publishing - Sanford Stem Cell Symposium 2024

Science (Audio)

Play Episode Listen Later Feb 18, 2025 58:38


Karen Christman, Sheila Chari, Stella Hurtley, and Robert Stephenson explore academic publishing in stem cell research, focusing on reproducibility, collaboration, and public communication. Editors from top journals discuss curating impactful research, sharing clinical trial data, and addressing challenges in scaling and standardizing therapies. They emphasize bridging silos, advancing precision regenerative medicine, and navigating open access publishing to responsibly propel the field forward. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39940]

UC San Diego (Audio)
Stem Cells Scientific Publishing - Sanford Stem Cell Symposium 2024

UC San Diego (Audio)

Play Episode Listen Later Feb 18, 2025 58:38


Karen Christman, Sheila Chari, Stella Hurtley, and Robert Stephenson explore academic publishing in stem cell research, focusing on reproducibility, collaboration, and public communication. Editors from top journals discuss curating impactful research, sharing clinical trial data, and addressing challenges in scaling and standardizing therapies. They emphasize bridging silos, advancing precision regenerative medicine, and navigating open access publishing to responsibly propel the field forward. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39940]

Health and Medicine (Video)
The Future of Precision Medicine: Stem Cells Gene Therapy and AI - Medicine Informing Novel Discoveries (MIND)

Health and Medicine (Video)

Play Episode Listen Later Jan 24, 2025 57:36


Learn about advancements in precision medicine, particularly the role of AI, stem cell research, and gene therapy. Experts highlight AI's potential in personalized treatments, diagnostics, and patient care. Key topics include RNA targeting therapies, base editing for gene mutations, and using stem cells for disease modeling and regeneration. AI's contribution to enhancing healthcare efficiency and decision-making is also explored, emphasizing its role in personalized medicine through large data sets. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39981]

University of California Audio Podcasts (Audio)
The Future of Precision Medicine: Stem Cells Gene Therapy and AI - Medicine Informing Novel Discoveries (MIND)

University of California Audio Podcasts (Audio)

Play Episode Listen Later Jan 24, 2025 57:36


Learn about advancements in precision medicine, particularly the role of AI, stem cell research, and gene therapy. Experts highlight AI's potential in personalized treatments, diagnostics, and patient care. Key topics include RNA targeting therapies, base editing for gene mutations, and using stem cells for disease modeling and regeneration. AI's contribution to enhancing healthcare efficiency and decision-making is also explored, emphasizing its role in personalized medicine through large data sets. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39981]

Health and Medicine (Audio)
The Future of Precision Medicine: Stem Cells Gene Therapy and AI - Medicine Informing Novel Discoveries (MIND)

Health and Medicine (Audio)

Play Episode Listen Later Jan 24, 2025 57:36


Learn about advancements in precision medicine, particularly the role of AI, stem cell research, and gene therapy. Experts highlight AI's potential in personalized treatments, diagnostics, and patient care. Key topics include RNA targeting therapies, base editing for gene mutations, and using stem cells for disease modeling and regeneration. AI's contribution to enhancing healthcare efficiency and decision-making is also explored, emphasizing its role in personalized medicine through large data sets. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39981]

UC San Diego (Audio)
The Future of Precision Medicine: Stem Cells Gene Therapy and AI - Medicine Informing Novel Discoveries (MIND)

UC San Diego (Audio)

Play Episode Listen Later Jan 24, 2025 57:36


Learn about advancements in precision medicine, particularly the role of AI, stem cell research, and gene therapy. Experts highlight AI's potential in personalized treatments, diagnostics, and patient care. Key topics include RNA targeting therapies, base editing for gene mutations, and using stem cells for disease modeling and regeneration. AI's contribution to enhancing healthcare efficiency and decision-making is also explored, emphasizing its role in personalized medicine through large data sets. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39981]

Brain Channel (Video)
Uncovering Mechanisms of Neurodegenerative Diseases by CRISPR-Based Screens with Martin Kampmann

Brain Channel (Video)

Play Episode Listen Later Jan 3, 2025 58:22


Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]

Science (Video)
Uncovering Mechanisms of Neurodegenerative Diseases by CRISPR-Based Screens with Martin Kampmann

Science (Video)

Play Episode Listen Later Jan 3, 2025 58:22


Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]

Health and Medicine (Video)
Uncovering Mechanisms of Neurodegenerative Diseases by CRISPR-Based Screens with Martin Kampmann

Health and Medicine (Video)

Play Episode Listen Later Jan 3, 2025 58:22


Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]

University of California Audio Podcasts (Audio)
Uncovering Mechanisms of Neurodegenerative Diseases by CRISPR-Based Screens with Martin Kampmann

University of California Audio Podcasts (Audio)

Play Episode Listen Later Jan 3, 2025 58:22


Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]

Health and Medicine (Audio)
Uncovering Mechanisms of Neurodegenerative Diseases by CRISPR-Based Screens with Martin Kampmann

Health and Medicine (Audio)

Play Episode Listen Later Jan 3, 2025 58:22


Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]

Science (Audio)
Uncovering Mechanisms of Neurodegenerative Diseases by CRISPR-Based Screens with Martin Kampmann

Science (Audio)

Play Episode Listen Later Jan 3, 2025 58:22


Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]

Health and Medicine (Video)
A Closer Look at…Stem Cells and the Human Brain

Health and Medicine (Video)

Play Episode Listen Later Dec 23, 2024 57:28


Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

University of California Audio Podcasts (Audio)
A Closer Look at…Stem Cells and the Human Brain

University of California Audio Podcasts (Audio)

Play Episode Listen Later Dec 23, 2024 57:28


Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

Health and Medicine (Audio)
A Closer Look at…Stem Cells and the Human Brain

Health and Medicine (Audio)

Play Episode Listen Later Dec 23, 2024 57:28


Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

Health and Medicine (Video)
A Tale of Two Barriers: Plasticity of Lung Epithelium and Mesothelium

Health and Medicine (Video)

Play Episode Listen Later Dec 18, 2024 58:40


Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]

University of California Audio Podcasts (Audio)
A Tale of Two Barriers: Plasticity of Lung Epithelium and Mesothelium

University of California Audio Podcasts (Audio)

Play Episode Listen Later Dec 18, 2024 58:40


Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]

Health and Medicine (Audio)
A Tale of Two Barriers: Plasticity of Lung Epithelium and Mesothelium

Health and Medicine (Audio)

Play Episode Listen Later Dec 18, 2024 58:40


Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]

Science (Video)
Restoration of T Cell Development in CD3δ SCID Through Adenine Base-Editing with Gloria Yiu - Sanford Stem Cell Symposium 2024

Science (Video)

Play Episode Listen Later Dec 2, 2024 28:12


Gloria Yiu, M.D., Ph.D., delves into the transformative potential of genetic editing technologies in addressing rare immune disorders, with a focus on CD3δ severe combined immunodeficiency (SCID)—a condition characterized by impaired T-cell development and severely compromised immune function. Leveraging her expertise as a physician-scientist, Yiu explores how CRISPR and other precision gene-editing tools can correct genetic mutations at the cellular level, potentially restoring T-cell production and immune resilience in patients with CD3δ SCID. Her presentation underscores the challenges and breakthroughs in treating such life-threatening conditions, emphasizing the role of interdisciplinary research, clinical innovation, and ethical considerations in advancing the frontiers of personalized medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40245]

Health and Medicine (Video)
Restoration of T Cell Development in CD3δ SCID Through Adenine Base-Editing with Gloria Yiu - Sanford Stem Cell Symposium 2024

Health and Medicine (Video)

Play Episode Listen Later Dec 2, 2024 28:12


Gloria Yiu, M.D., Ph.D., delves into the transformative potential of genetic editing technologies in addressing rare immune disorders, with a focus on CD3δ severe combined immunodeficiency (SCID)—a condition characterized by impaired T-cell development and severely compromised immune function. Leveraging her expertise as a physician-scientist, Yiu explores how CRISPR and other precision gene-editing tools can correct genetic mutations at the cellular level, potentially restoring T-cell production and immune resilience in patients with CD3δ SCID. Her presentation underscores the challenges and breakthroughs in treating such life-threatening conditions, emphasizing the role of interdisciplinary research, clinical innovation, and ethical considerations in advancing the frontiers of personalized medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40245]

University of California Audio Podcasts (Audio)
Restoration of T Cell Development in CD3δ SCID Through Adenine Base-Editing with Gloria Yiu - Sanford Stem Cell Symposium 2024

University of California Audio Podcasts (Audio)

Play Episode Listen Later Dec 2, 2024 28:12


Gloria Yiu, M.D., Ph.D., delves into the transformative potential of genetic editing technologies in addressing rare immune disorders, with a focus on CD3δ severe combined immunodeficiency (SCID)—a condition characterized by impaired T-cell development and severely compromised immune function. Leveraging her expertise as a physician-scientist, Yiu explores how CRISPR and other precision gene-editing tools can correct genetic mutations at the cellular level, potentially restoring T-cell production and immune resilience in patients with CD3δ SCID. Her presentation underscores the challenges and breakthroughs in treating such life-threatening conditions, emphasizing the role of interdisciplinary research, clinical innovation, and ethical considerations in advancing the frontiers of personalized medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40245]

Winning the War on Cancer (Video)
Infectious Disease Breakthroughs - Medicine Informing Novel Discoveries (MIND)

Winning the War on Cancer (Video)

Play Episode Listen Later Nov 30, 2024 56:10


The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]

Science (Video)
Infectious Disease Breakthroughs - Medicine Informing Novel Discoveries (MIND)

Science (Video)

Play Episode Listen Later Nov 30, 2024 56:10


The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]

Health and Medicine (Video)
Infectious Disease Breakthroughs - Medicine Informing Novel Discoveries (MIND)

Health and Medicine (Video)

Play Episode Listen Later Nov 30, 2024 56:10


The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]

University of California Audio Podcasts (Audio)
Infectious Disease Breakthroughs - Medicine Informing Novel Discoveries (MIND)

University of California Audio Podcasts (Audio)

Play Episode Listen Later Nov 30, 2024 56:10


The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]

Science (Video)
What Makes a Stem Cell a Stem Cell and How Does it Go Bad? with John Dick - Sanford Stem Cell Symposium 2024

Science (Video)

Play Episode Listen Later Nov 25, 2024 45:32


John Dick, Ph.D., F.R.S., explores the role of CD83, a molecule found in blood stem cells, in how these cells respond to inflammation. His team demonstrates that CD83 becomes highly active during inflammation and contributes to the loss of healthy stem cells. Using advanced gene-editing tools, they show that removing CD83 protects stem cells from inflammation-related damage. This discovery highlights CD83 as a potential marker for identifying inflamed stem cells and as a possible target for treatments to improve recovery after stem cell transplants. He also discusses early findings on potential differences in blood stem cell behavior between men and women and raises questions about how inflammation from severe illnesses, like COVID-19, could impact the blood system as we age. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39949]

Health and Medicine (Video)
What Makes a Stem Cell a Stem Cell and How Does it Go Bad? with John Dick - Sanford Stem Cell Symposium 2024

Health and Medicine (Video)

Play Episode Listen Later Nov 25, 2024 45:32


John Dick, Ph.D., F.R.S., explores the role of CD83, a molecule found in blood stem cells, in how these cells respond to inflammation. His team demonstrates that CD83 becomes highly active during inflammation and contributes to the loss of healthy stem cells. Using advanced gene-editing tools, they show that removing CD83 protects stem cells from inflammation-related damage. This discovery highlights CD83 as a potential marker for identifying inflamed stem cells and as a possible target for treatments to improve recovery after stem cell transplants. He also discusses early findings on potential differences in blood stem cell behavior between men and women and raises questions about how inflammation from severe illnesses, like COVID-19, could impact the blood system as we age. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39949]

University of California Audio Podcasts (Audio)
What Makes a Stem Cell a Stem Cell and How Does it Go Bad? with John Dick - Sanford Stem Cell Symposium 2024

University of California Audio Podcasts (Audio)

Play Episode Listen Later Nov 25, 2024 45:32


John Dick, Ph.D., F.R.S., explores the role of CD83, a molecule found in blood stem cells, in how these cells respond to inflammation. His team demonstrates that CD83 becomes highly active during inflammation and contributes to the loss of healthy stem cells. Using advanced gene-editing tools, they show that removing CD83 protects stem cells from inflammation-related damage. This discovery highlights CD83 as a potential marker for identifying inflamed stem cells and as a possible target for treatments to improve recovery after stem cell transplants. He also discusses early findings on potential differences in blood stem cell behavior between men and women and raises questions about how inflammation from severe illnesses, like COVID-19, could impact the blood system as we age. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39949]

Health and Medicine (Video)
Space-Based Research: Predicting and Preventing Accelerated Stem Cell Aging and Cancer Evolution with Catriona Jamieson - Sanford Stem Cell Symposium 2024

Health and Medicine (Video)

Play Episode Listen Later Nov 18, 2024 28:29


Catriona Jamieson, M.D., Ph.D., discusses pioneering research on cancer and aging in space environments, highlighting how microgravity accelerates cancer cell growth and leads to stem cell exhaustion, genomic instability, and “dark genome” activation. Using innovative tools like nano-bioreactors and artificial intelligence, her team simulates these effects and tracks cellular changes, uncovering how space's unique conditions drive mutations and alter cellular behavior. They find that stem cells rapidly proliferate but then become exhausted in space, a process tied to telomere shortening and mitochondrial stress, impacting cell longevity and regenerative potential. Through collaborations with NASA and industry partners, Jamieson's research aims to develop therapies to counter these effects, offering potential insights for cancer treatment and stem cell health on Earth. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39948]

Winning the War on Cancer (Video)
Unlocking the Secrets of Aging and Longevity with Stem Cells

Winning the War on Cancer (Video)

Play Episode Listen Later Oct 28, 2024 20:48


Curious about the secret to staying young? Rob Signer shares insights into how our bodies age, focusing on the role of stem cells and a critical protein called HSF1 that helps them cope with stress. Signer explores the delicate balance of keeping these cells healthy without increasing cancer risk and highlighted some promising progress in enhancing the cells' ability to manage waste. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39980]