Podcasts about Neurodegeneration

For more information and support, visit us at our NEW WEBSITE! https://www.thecirsgroup.com This week, we are continuing our recap of the CIRSx 2025 conference! Today, we are focusing on the treatment talks: Understanding the Pitfalls of Tick Borne Testing with Christian Navarro Torres, PhD, CIRS Lab Finding the Tick-Borne Needle in the Haystack: Tick Borne Infections in CIRS Patients with Peg DiTulio, DNP, APRN Diagnosing Lyme and Co-infections: An Investigation of the Availability, Diversity and Validity of the Current Testing with Dr. Laura Varga, DAOM Air Oasis EdTalk with Brad Baxter, COO A Unifying Theory of Neurodegeneration with Dr. Dale Bredesen The Actinobacteria Reduction Study: Making Life Easier for the CIRS Community with Eric Dorninger, ND, LAc Brain Injury in CIRS: From Specific Causation to a Unique Transcriptomic Fingerprint in Parkinson's with Dr. Ritchie Shoemaker The Principles of Body Typing as a Critical Tool for CIRS Success with Erin Livers , BA, ICNT Evidence-based Diagnoses and Strategies for the CIRS Microbiome with Dr. Lacey Venazi For more information and support, visit us at our NEW WEBSITE! https://www.thecirsgroup.com TIMESTAMPS 00:00 Introduction and disclaimer 00:45 Tick-Borne testing insights by Dr. Christian Navarro-Torres, Dr. Peg DiTulio, Dr. Laura Varga 09:02 AirOasis ED Talk by Brad Baxter 11:19 Dr. Dale Bredesen's Keynote on Alzheimer's and Neurodegeneration 15:46 Actinobacteria Reduction Study by Dr. Eric Dorninger 18:20 Dr. Shoemaker's Talk on Parkinson's Research 20:45 Principles of Body Typing for Nutrition by Nutritionist Erin Livers 23:23 CIRS and the Gut Microbiome by Dr. Lacey Venazi 27:41 Conclusion and Additional Resources Helpful links/info: CIRSx website: https://www.cirsx.com/ Dr. Christian Navarro-Torres' website: https://www.cirslab.com/ Dr. Peg DiTulio's website: https://regenixhealing.com/ Dr. Laura Varga: https://www.instagram.com/thejupiterapproach/ or email her at TheJupiterApproach@gmail.com Air Oasis website: https://www.airoasis.com/ Dr. Dale Bredesen's website: https://www.apollohealthco.com/dr-bredesen/ The Flow Free game Jacie plays: https://www.bgames.com/game/flow-free-online/ Our last CIRSx recap episode: https://youtu.be/0aLD_1ixWXU?si=5-DxFVxgy7dleux3 Dr. Eric Dorninger's website: https://drdorninger.com/ Dr. Ritchie Shoemaker's website: https://www.survivingmold.com/ Erin Livers' website: https://foodasnourishment.com/ Dr. Abravanel's Body Type Diet and Lifetime Nutrition Plan: https://a.co/d/g6Z1bP7 Dr. Lacey Venazi's website: https://www.drlacey.org/ Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs The CIRS Group: Support Community: https://thecirsgroup.com Instagram: https://www.instagram.com/thecirsgroup/ Find Jacie for carnivore, lifestyle and limbic resources: Jacie's book on the Carnivore diet!  https://a.co/d/8ZKCqz0 Instagram: https://www.instagram.com/ladycarnivory YouTube: https://www.youtube.com/@LadyCarnivory Blog: https://www.ladycarnivory.com/ Find Barbara for business/finance tips and coaching: Website: https://www.actlikebarbara.com/ Instagram: https://www.instagram.com/actlikebarbara/ YouTube: https://www.youtube.com/@actlikebarbara Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.

PhD in synthetic chemistry, the Product Formulator for Supplement Needs, and fitness industry renowned Pharmacologist for his no-nonsense approach in bodybuildingThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder:[ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaWatch it: https://www.youtube.com/watch?v=6Ihq4tIzyS8&t=5618sRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com2:19 Bodybuilding Pharmacology and Dosing4:53 Brain Health and Long-Term Risks7:29 Muscle Building and Genetic Factors10:03 Cholesterol and LDL Impacts12:14 Podcast Setup and Equipment Upgrades14:34 Hair Transplant Journey24:23 Hair Loss Causes and Treatments34:59 Post-Transplant Recovery and Rebound39:31 Epigenetics and Muscle Memory43:04 Ethical Questions on Genetic Enhancement45:40 Enhanced Games Debate50:09 Dosing Challenges in Enhanced Sports52:32 Data Collection and Human Experimentation55:16 Genetic Variance and Elite Athletes59:04 Neurodegeneration and PEDs1:07:08 Oxidative Stress in Bodybuilding1:09:37 Sleep and Brain Detox1:18:01 Nutrition for Oxidative Stress1:19:02 Melatonin as an Antioxidant1:21:13 Melatonin Dosing and Effects1:24:51 Melatonin and Sleep Support Supplements1:28:22 Magnesium and Sleep Health1:31:23 Sleep Apnea and Neural Health1:36:30 Frequent Urination at Night1:46:33 Overheating During Sleep1:59:14 Wrapping Up Oxidative Stress2:00:33 Neuron Loss and Neurotransmitters2:02:04 Boosting Brain Health with BDNF2:04:08 Peptides for Neural Growth2:09:14 Oxidative Stress and Supplements2:12:34 Neuroprotection Strategies2:19:56 EMF and Environmental Stressors2:22:12 Mitochondrial Dysfunction and Aging2:24:55 Balancing Oxidative Stress2:28:32 Steroids and Muscle Growth Rates2:38:54 HDL and LDL Control Ancillaries2:41:34 Statins and LDL Oxidation2:47:36 Antioxidants and Plaque Formation2:54:10 Balancing Cholesterol Levels2:58:35 CT Scans for Heart Health3:03:54 Heart Health Supplements3:06:48 Mitochondrial Stack Under 303:16:27 Balanced Diet in Prep3:20:24 Omega-3 and Fish Oil Quality3:23:36 Podcast Wrap-Up

This episode of Integrative You Radio dives deep into the misunderstood world of neurodegenerative diseases—especially ALS (Amyotrophic Lateral Sclerosis). Dr. Nicole and Dr. Nick unravel the hidden connections between environmental toxins, like cyanide and algae exposure, and the emotional roots of disease, such as self-betrayal and the “Nice Guy Syndrome.” They challenge the conventional view of ALS as just a physical diagnosis, shining a light on how a lack of self-love and unexpressed truth can manifest physically. The Doctors share practical wisdom on breaking free from people-pleasing, the importance of knowing your values, and how real healing starts with radical self-awareness and communication.   #ALS #NeurodegenerativeDisease #SelfLove #IntegrativeMedicine #RootCauseHealing #PeoplePleasing #ValuesDriven #FunctionalMedicine #EmotionalHealth #SpeakYourTruth #HolisticHealth #MindBodyConnection #WellnessJourney #DrNicoleRivera #DrNickCarruthers #IntegrativeYou   3 Key Takeaways: ALS and other neurodegenerative diseases may be linked to cyanide exposure—not just from the environment but from internal sources like cyanobacteria (blue-green algae), highlighting the need for deeper diagnostic approaches. Long-term people-pleasing, self-betrayal, and putting yourself last (especially for parents and caregivers) can create profound stress and disconnection from self, which may contribute to disease. True healing begins with radical self-love, clear communication, and living in alignment with your core values—knowing who you are is the foundation for transformation.    Quotes:  “Every single aspect of disease is literally how far away from love are you? And that will equal the degree of the disease.” – Dr. Nick “If you're not going to speak up and exercise your truth, or stand for yourself, you're mentally not speaking up—and that can manifest as a physical disease.” – Dr. Nicole   Find Integrative You Radio On: Website Youtube  Apple Spotify   2 Doctors Committed to Innovating the Healthcare Experience. Integrative You Radio is hosted by husband-and-wife duo, Dr. Nicole Rivera and Dr. Nick Carruthers. With their voracious curiosity for Integrative Medicine, the Human Mind, Aligned Parenting, and Entrepreneurship, they bring a fresh perspective to the table. They aim to debunk the BS that is holding you back in your health, your relationships, and your life. Each episode is designed to challenge your thinking, push boundaries, and inspire you to see your life through a new lens. Dr. Nicole and Dr. Nick share transformative insights that have revolutionized their lives and the lives of their clients at Integrative You. This is raw. This is real. This is Integrative You Radio— where we blow shit up for the sake of human innovation.   Links: Website: Integrative You Instagram: Dr. Nicole Rivera & Integrative You Ready to Move from Awareness to Action? If today's episode on ALS and neurodegenerative disease resonated with you—if you saw yourself in the conversation about people-pleasing, self-betrayal, or putting yourself last—don't let this be just another inspiring listen. Take the next step toward real change: Start With Your Core: We talked about how true healing starts with knowing your values and who you are at your core. Our Values Determination Course is the perfect place to begin if you're ready to break old patterns, set new boundaries, and create a life aligned with your truth. Discover your values and start your transformation here: https://www.integrativeyou.health/offers/nkCsvtRJ/checkout  Strengthen Your Relationships: If you realized your communication rhythms at home need a reset, or you're ready to move beyond surface-level connection with your partner, our Aligned Couples Course gives you the exact strategies we use for real, lasting partnership and honest feedback. Elevate your relationship—get started with the Aligned Couples Course: https://www.integrativeyou.health/offers/BZzwFLW3/checkout   Get Personalized, Root-Cause Care: For those who want to dig deeper—whether you're facing chronic illness, mystery symptoms, or just want a high-touch, holistic approach—our Concierge Integrative Medicine program is here for you. We blend advanced diagnostics, values work, and ongoing support so you're not just treating symptoms, but rewriting your story from the inside out. Apply for your private integrative experience now: https://www.integrativeyou.health/onboarding  You don't have to settle for “just getting by.” Whether you're ready to do the inner work, transform your relationships, or get truly personalized care, we're here to help you create your Limitless 2.0 life.   Got questions? You can call or text us at 732-810-1084.

This episode features Prof. Dr. Robert Perneczky who serves as Professor of Translational Dementia Research and Head of Geriatric Psychiatry at Ludwig-Maximilians University in Munich. Dive into the intricate realm of dementia and neurocognitive disorders as he reveals groundbreaking advancements in disease-modifying treatments and emphasizes the crucial role of lifestyle factors in mitigating dementia risk. Explore how cutting-edge innovations in biomarkers and interdisciplinary methodologies are revolutionizing the future of dementia care and gain insightful strategies to enhance resilience against neurodegeneration.

In this episode:The seven foods and nutrients shown to promote and protect long term brain healthWhere should you save your moneyWhat a day of neuro-nourishing eating might look like___Newsletter sign upCorporate Speaking How to Build a Healthy Brain* Unprocessed: What Your Diet is Doing to Your Brain* Patreon Original music by Juan Iglesias *Affiliate links The information shared on this podcast is for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition or treatment. Never disregard professional medical advice or delay in seeking it because of something you heard on this podcast. Reliance on any information provided here is solely at your own risk. Remember, your health is unique to you, so consult your healthcare provider for guidance tailored to your personal needs.Support this show http://supporter.acast.com/strongerminds. Hosted on Acast. See acast.com/privacy for more information.

 In this episode, we dive into the tiny but powerful molecule called NAD+ — the fuel your cells need to create energy, repair damage, and keep you feeling young and strong. As we age, NAD+ levels drop, and that can lead to low energy, slower healing, and more health problems. But here's the exciting part: science is showing that we can boost NAD+ through smart lifestyle habits and supplements — helping improve energy, brainpower, heart health, and even slow down aging. We'll break it all down in simple terms:  ✅ What NAD+ does in your body  ✅ Why it matters for your health and aging  ✅ How to naturally boost your NAD+ levels  ✅ What new research is saying about its future If you want to unlock more energy, sharper thinking, and better long-term health, this episode is for you! Tune in and learn how to help your body thrive — from the inside out.

Big shift in Alzheimer's care! We can now predict it years in advance using

In this eye-opening episode of the Whole Body Detox Show, David DeHaas of Living Waters Wellness Center uncovers shocking facts about everyday toxins—starting with Ziploc bags, which can leach microplastics and heavy metals into food when microwaved or frozen. Learn why switching to glass containers is critical for reducing toxic exposure.David draws from the Blaylock Wellness Report to explore the root causes of neurodegeneration, including Alzheimer's, Parkinson's, Multiple Sclerosis (MS), and ALS. He explains how brain fog, cognitive decline, and other neurological disorders are often triggered by environmental toxins, vaccinations, glutamate, and impaired mitochondrial function.You'll hear powerful stories of transformation from our 10-Day Healing Retreat, where deep detoxification, emotional healing, and muscle testing (kinesiology) have helped clients overcome symptoms like memory loss, tremors, and even regain mobility from wheelchairs.Discover the neurological power of Vitamin B6 (P5P), Riboflavin (Vitamin B2), Thiamine (Vitamin B1), and Benfotiamine, along with Green Tea Extract (EGCG)—nutrients shown to support dopamine production, reduce excitotoxicity, and enhance mitochondrial energy and brain health.David also exposes the dangers lurking in biosolids, used in city parks and farmland, which carry pesticides, heavy metals, and animal waste. Plus, learn why assisted living centers restrict access to life-saving supplements and how you can stay independent through natural detox, energy healing, and proper nutrition.Holistic tools like Trauma Plant (comfrey cream), nanocurcumin, and healing touch energy therapy are also featured—practical ways to reduce inflammation and support recovery without toxic pharmaceuticals like Tylenol.Take the first step toward holistic health and a toxin-free future.

About the Guest(s): Dr. Kristin Hieshetter is a distinguished figure in the field of functional health. Known for her dedication to improving healthcare outcomes, she hosts "Functional Health Radio," which focuses on contemporary health challenges and innovative solutions. She has an extensive healthcare background, including specialties in cardiology, neurology, biofeedback, and nutritional biochemistry. Her passion for empowering individuals to realize their full potential positions her as a leading voice for transformative health practices. Dr. Laura Standridge is an engaged and knowledgeable mother of a child with BPAN (Beta-Propeller Protein-Associated Neurodegeneration). She collaborates with Dr. Kristin Hieshetter on the Functional Health Radio podcast to share insights on managing neurodegenerative conditions through innovative dietary, therapeutic, and technological interventions. Her training, which includes clinical expertise and use of biofeedback and mitochondrial devices, offers a valuable perspective on caring for children with complex health needs. Episode Summary: In this episode of Functional Health Radio, Dr. Kristin Hieshetter dives deep into the alarming statistics surrounding declining U.S. life expectancy and the uptick in chronic conditions among children, sparking discussions on healthcare spending and health optimization. The episode progresses with an exploration of BPAN (Beta-Propeller Protein-Associated Neurodegeneration) and the intricacies of managing this rare neurodegenerative disorder through strategic dietary choices and advanced therapeutic interventions. A special focus is placed on addressing iron accumulation in the brain and the growing trend of neurodevelopmental conditions influenced by environmental toxins. Dr. Hieshetter, alongside guest Dr. Laura , elaborates on strategies to reduce iron intake, utilize mitochondrial support, and implement innovative therapies such as biofeedback devices and low-level lasers to promote brain health. A moving discussion about Dr. Laura son, Laird unveils practical implementations of technology-aided therapies in clinical settings. Through these discussions, the episode underscores the vital roles of therapeutic collaboration and continued parental involvement in treating neurodegenerative disorders. Essential references to books like "The Iron Curse" by Dr. Christy Sutton and devices aiding neurodevelopment offer an enlightening perspective on progressive healthcare. Key Takeaways: Iron Management in BPAN: Limiting iron intake is crucial for managing BPAN, particularly avoiding high-iron foods and choosing suitable alternatives. Innovative Therapies: Utilizing devices such as TENS units, Resimax, and Erconia lasers can substantially aid in treating neurodegenerative conditions by enhancing cellular energy and brain function. Environmental Toxin Awareness: Reducing exposure to environmental toxins like PFAS is critical in managing and mitigating neurodevelopmental disorders. Integrative Health Interventions: Combining chiropractic, neurology, and nutritional insights leads to more comprehensive treatment approaches for complex health conditions. Power of Movement: Ensuring movement, even passive, in children with developmental challenges plays a vital role in maintaining brain health and function. Notable Quotes: "We are walking around in the most amazing, intelligent, responsive, adapting, and aware system in the world, the human you." — Dr. Kristin Hieshetter "Everything you put in that kid's body is going to immediately help or immediately harm that child." — Dr. Kristin Hieshetter "If you're interested in learning more about that iron and what is happening, 'The Iron Curse' by Dr. Christy Sutton is amazing." — Dr. Kristin Hieshetter "His typical BPAN trajectory is not happening with her son because we're doing so many other things." — Dr. Kristin Hieshetter "The neat thing about the continued quest for knowledge is that you stack in all these other things because you know there's going to be things in there that can help that patient." — Dr. Kristin Hieshetter Resources: Dr. Christy Sutton's Book: [The Iron Curse](Not provided in the transcript) Dr. William Davis' Books: "Undoctored" and "Wheat Belly Diet" David Perlmutter's Book: "Grain Brain" Erconia Lasers: Erconia Medical (unprovided in transcript) Functional Health Mastery Group Device and Therapy: Forebrain headsets, TENS units, Resimax, and Kirtan Kriya audio meditations Listeners are encouraged to tune into Functional Health Radio to delve deeper into essential topics related to health innovation and management and to stay informed about forthcoming episodes packed with insightful discussions and expert perspectives.

About the Guest(s): Dr. Laura Standridge: Dr. Laura Standridge is a prominent functional chiropractor known for her expertise in pediatric neurological development and genetic disorders. She is board certified in neurofeedback and specializes in approaches that focus on neurodevelopmental assessments, particularly concerning mitochondrial function and primitive reflexes. Dr. Standridge has gained attention for her work with rare neurodegenerative disorders, particularly BPAN, following her son's diagnosis with the disease. Her professional journey is marked by a dedication to understanding and improving neurological health through innovative methods in functional and integrative healthcare. Episode Summary: In this enlightening episode of Functional Health Radio, Dr. Kristin Hieshetter delves deep into the pressing health crises in America, revealing that the country's life expectancy has not only plateaued but declined for both men and women. Despite the high per capita healthcare expenditure, conditions like heart disease and cancer remain prevalent, and children are increasingly diagnosed with chronic diseases. The discussion transitions into a heartfelt narrative with Dr. Laura Standridge, a functional chiropractor passionately occupied with her son Laird's rare neurodegenerative disease known as BPAN (Beta-propeller Protein-Associated Neurodegeneration). BPAN, characterized by iron accumulation in the brain, is a daunting diagnosis for any family, but Dr. Standridge shares her proactive approach to defy the medical script of decline. Employing advanced genetic testing and leveraging her deep understanding of functional health principles, Dr. Standridge explores comprehensive interventions that have led to remarkable outcomes for Laird. From dietary adjustments to specialized neurodevelopmental therapies and state-of-the-art medical interventions, Dr. Standridge's narrative underscores a hopeful perspective—not only sharing insights about BPAN but also reflecting innovative applications of functional health practices. This episode highlights how a blend of cutting-edge science and compassionate care can write new chapters in health and wellness narratives. Key Takeaways: BPAN Disease Insight: BPAN is a rare neurodegenerative disorder that causes abnormal iron accumulation in the brain, significantly impairing mitochondrial function and autophagy. Unique Case of Laird: Laird defies the typical BPAN trajectory through a tailored combination of nutritional strategies, functional therapies, and mitochondrial enhancement techniques. Importance of Nutrition: Laird's diet, free of gluten and inflammatory foods, supports brain health by preventing autoimmune responses that can exacerbate neurological damage. Integrative Approaches: Utilization of genetic testing and innovative therapies, like low-level laser therapy, provides neuroprotective benefits and enhances Laird's quality of life. Collaborative Healthcare: Dr. Standridge exemplifies the power of interdisciplinary collaboration, uniting various specialists to support a functional health-driven roadmap for Laird. Notable Quotes: "We are walking around in the most amazing, intelligent, responsive, adapting and aware system in the world, the human. Let's bring it to its fullest potential." - Dr. Kristin Hieshetter "It doesn't matter what the label is…I'm much more interested in how you are functioning and not what somebody from the outside might call you." - Dr. Laura Standridge "We waited and we waited and we waited some more and finally received this diagnosis." - Dr. Laura Standridge "The brain is built on the postural system…and so there is this amazing order of neurological development whether you have a genetic difference or not." - Dr. Laura Standridge "Together, we'll be the change that we wish to see in the world." - Dr. Kristin Hieshetter Resources: Learn more about BPAN and related genetic testing at the CDC Vital Statistics Report: www.cdc.gov For insights into functional chiropractic care and Dr. Laura Standridge's approaches, visit Functional Health Mastery Stay informed with the World Economic Forum's health expenditure data: www.weforum.org Functional Health Mastery Group Listen to the full episode to dive deeper into the revolutionary approaches that Dr. Laura Standridge and Dr. Kristin Hieshetter share in tackling BPAN, and stay tuned for more inspiring stories and informative discussions on Functional Health Radio.

About the Guest(s): Dr. Kristin Hieshetter: Dr. Kristin Hieshetter is a distinguished functional health professional renowned for her integrative approach to wellness. With a strong background in neurodegenerative disease management and gut health, Dr. Hieshetter has been impacting lives through her podcast, "Functional Health Radio." Her dedication to evidence-based practice has propelled her podcast to the top 10% of global rankings in just six months. Dr. Hieshetter's clinical practice is underpinned by rigorous research, patient-centered care, and a deep commitment to improving health outcomes through innovative approaches like low-level laser therapy. Episode Summary: In this compelling episode of Functional Health Radio, Dr. Kristin Hieshetter delves into the intricacies of gut health and its profound impact on overall wellness. She opens with a nod to her previous episode about low-level laser therapy in neurodegenerative diseases and its life-changing potential for children. Transitioning into the current discussion, Dr. Hieshetter elaborates on how gut health significantly influences various symptoms like GI upset, brain fog, and mental health deterioration, emphasizing a holistic clinical approach. Amid her exploration of gut microbiome, Dr. Hieshetter sheds light on the critical role of nutritional choices and exposure to toxins such as MSG, aspartame, and glyphosate. Highlighting the connection between gut imbalances and systemic diseases, she shares a powerful story of a patient who traveled from Florida seeking relief from chronic gastrointestinal issues. Through advanced gut testing, Dr. Hieshetter outlines her integrative treatment strategies, underscoring the significance of vibrant gut health and its direct correlation with mental well-being, autoimmune disorders, and even neurological diseases like Parkinson's. Key Takeaways: Gut health is intricately linked to brain health, influencing symptoms like anxiety, depression, and cognitive decline. Functional testing, such as Vibrant America's Gut Zoomer, plays a vital role in diagnosing and treating gut imbalances. Avoiding harmful substances like excitotoxins and pesticides is crucial for maintaining gut and overall health. Comprehensive treatment plans, including probiotics, dietary changes, and low-level laser therapy, can significantly improve quality of life. Emotional and mental health often improve alongside physical well-being in cases of severe gut imbalances. Notable Quotes: "When there are things that I know the world needs, I know my patients need, they keep walking through my door without me asking." "Your gut microbiome is a major protector of that." "Pesticides like paraquat, they inhibit autophagy… It cleans out cancer cells that shouldn't be there." "Stop eating pesticides. Avoid them at all costs." "It's a really different topic to check out, but for the repeat listeners, you know, it's been a great journey for us all here." Resources: Vibrant America - Website Journal of Environmental Toxicology 2022 Journal of Parkinson's Disease 2023 Environmental Working Group (EWG) - Website Pelican S.L. Pentair Water Filtration System Functional Health Mastery Group Trends in Neuroscience 2013 For those seeking to enhance their understanding of functional health and explore transformative approaches to wellness, this episode is a must-listen. Tune in next week for more illuminating content from Functional Health Radio, where Dr. Kristin Hieshetter continues to share insights that can change the face of healthcare.

In this compelling episode of Research Renaissance, host Deborah Westphal sits down with Jackson Mace, a neuroscience PhD candidate at Johns Hopkins University and 2023 Toffler Scholar, to explore the cutting-edge research driving our understanding of neurodegenerative diseases—particularly multiple sclerosis (MS).Drawing from personal experience—his father's MS diagnosis—and a deep academic curiosity, Jackson shares the winding path that led him from undergraduate lab work to a promising career in neuroimmunology. Together, they discuss:

Revolutionizing Regenerative Medicine: The Power of Mass-Produced Mitochondria: Nutritionist Leyla Muedin explores groundbreaking research on stem cell-based methods to mass-produce human mitochondria, which could revolutionize regenerative and anti-aging medicine. She delves into the science and potential health benefits, discussing how increased mitochondrial production can improve conditions like osteoarthritis, heart disease, and neurodegenerative disorders. Leyla also provides practical advice on ways to enhance mitochondrial health through dietary and supplement strategies, offering listeners actionable steps to boost their health span and lifespan.

What if you could reverse the age of your heart...without leaving home? In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You'll discover how mitochondrial decline drives heart failure, why postmenopausal women face skyrocketing cardiac risks, and how one powerful molecule, Urolithin A, can rejuvenate your heart's energy systems. Dr. Singh shares clinical research showing how Urolithin A improves mitochondrial function, boosts endurance, and may even reverse biological aging markers in the heart. You'll also learn how simple lifestyle biohacks, combined with cellular nutrition, can protect your cardiovascular health and extend your healthspan. What You'll Learn in This Episode: • The link between mitochondrial decline and heart failure • Why women's cardiac risk skyrockets after menopause • How Urolithin A stimulates mitophagy and energy renewal • New human clinical data on reversing cardiac aging markers • Biohacking strategies to fortify your cardiovascular health • How to optimize endurance, recovery, and heart resilience THANK YOU TO OUR SPONSORS! -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Timeline Website – https://www.timeline.com/partners/dave-asprey • Timeline Instagram - https://www.instagram.com/timeline_longevity/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 02:11 — Supplements that help • 03:05 — Long-term benefits • 04:38 — Stacking with lifestyle • 22:19 — Heart health connection • 29:39 — Mitochondria & brain function • 33:04 — Glymphatic system & Alzheimer's • 33:53 — Bed height & brain health • 34:18 — Why mitochondria matter • 35:43 — Inflammation & dysfunction • 38:12 — Transplants & consciousness • 39:19 — Meditation's effects • 40:33 — The ultimate biohacking stack • 43:06 — Creatine for sleep & focus • 50:00 — Fertility insights • 57:23 — Skin health • 01:00:28 — Final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

America Out Loud PULSE with Dr. Randall Bock – I investigate Alzheimer's, Parkinson's, and ALS neurodegeneration, revealing how protein aggregates, inflammation, and DNA damage drive brain decay. Using genetic markers, blood tests, animal models, lab‑grown mini‑brains, and NIH data, I aim to detect disease extremely early and develop targeted treatments that consider genetics and sex for more effective interventions.

America Out Loud PULSE with Dr. Randall Bock – I investigate Alzheimer's, Parkinson's, and ALS neurodegeneration, revealing how protein aggregates, inflammation, and DNA damage drive brain decay. Using genetic markers, blood tests, animal models, lab‑grown mini‑brains, and NIH data, I aim to detect disease extremely early and develop targeted treatments that consider genetics and sex for more effective interventions.

In this episode, we're going deep on Carbon 60—also known as C60 or buckyballs. If you've ever wondered how a molecule that started life as an industrial lubricant ended up a star player in the world of anti-aging, you're in for a treat. Ian and I talk about the original studies that blew everyone's minds (including a rat study where the animals lived nearly twice as long as expected!), and we discuss Ian's own hands-on research, from mouse models to dogs, horses, and even human applications.   What we discuss: C60 explained: origins, “buckyballs,” and research ... 00:08 C60 rat and mouse longevity studies ... 00:09 Lipid binding & targeted delivery ... 00:16 C60: antioxidant, adaptogen, mitochondrial effects ... 00:18 Athlete case study & performance benefits ... 00:25 Applications for fatigue, brain fog, metabolic issues ... 00:32 Autoimmune/inflammatory benefits & mitochondrial origins ... 00:34 Hair, scalp, and ovarian health ... 00:38 Neurodegeneration, glymphatics & brain serums ... 00:45 Optimizing cognition & cycling C60 ... 00:51 Safety notes: who should avoid and why ... 00:53 Product lineup & new developments ... 01:01 What to look for in C60 products ... 01:09   Our Amazing Sponsors: LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT10 for 10% off your order.   Peptide Pro App - When you're working with multiple peptides, timing and precision matter. From smart scheduling to real-time dose checklists, it keeps things organized and on track. Receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today.   Wizard Sciences (Neural Rx) - designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com.    Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

In this episode, I'm joined by Dr. Dale Bredesen, a true pioneer in Alzheimer's research and functional medicine. Together, we dive into groundbreaking advancements in the world of neurodegenerative diseases, with a special focus on the exciting breakthroughs in detecting and potentially reversing Alzheimer's and other related conditions. Dr. Bredesen sheds light on the new disease mechanisms and innovative blood tests that are changing the game, showing us that cognitive decline isn't something we simply have to accept. We also explore his integrative approach to combating Alzheimer's, which includes lifestyle modifications, early detection, and a holistic strategy for better brain health. This conversation is packed with hope and real strategies for a future where Alzheimer's doesn't have to be inevitable. Key Takeaways: New Era of Research: Alzheimer's and similar neurodegenerative diseases are not death sentences, thanks to innovative research and new treatment protocols that emphasize early detection and intervention. Significance of Gut Health: Investigations reveal that gut microbiota and inflammation are crucial risk factors in cognitive decline, underscoring the importance of gut health in preventing Alzheimer's. Role of Lifestyle Changes: Diet, exercise, sleep, and stress management are integral to maintaining brain health and can significantly influence the progression of neurodegenerative diseases. Advance in Diagnostics: Cutting-edge blood tests such as P Tau217 and brain scans can detect early signs of Alzheimer's up to 20 years prior to diagnosis, offering opportunities for preemptive action. The Power of Personalized Medicine: Individualized protocols based on genetic testing, like assessing APOE status, are pivotal in developing effective prevention and treatment strategies for cognitive disorders. More About Dr. Dale Bredesen: Dr. Dale Bredesen, M.D., is a globally recognized expert in neurodegenerative diseases, particularly Alzheimer's disease. With a background that includes graduating from Caltech and earning his M.D. from Duke University Medical Center, Dr. Bredesen's career is marked by groundbreaking research and clinical expertise. He completed his residency as chief resident in neurology at UCSF and further honed his skills at Nobel laureate Stanley Prusiner's lab at UCSF as an NIH postdoctoral fellow. Dr. Bredesen's academic career includes faculty positions at prestigious institutions like UCSF, UCLA, and UC San Diego. As the founding president and CEO of the Buck Institute for Research on Aging, he spearheaded pioneering work in the study of aging and neurodegenerative diseases. Currently, he serves as the chief medical officer of MPI Cognition, where he continues his innovative research and efforts to combat Alzheimer's and related conditions. Dr. Bredesen's expertise and leadership have made him a key figure in the field, with a focus on integrative approaches to prevent and reverse cognitive decline. His contributions are reshaping our understanding of neurodegenerative diseases, offering new hope for those affected by them. Website Instagram Take a Cognitive Assessment here: https://www.apollohealthco.com/know-your-cq/ Get a brain scan: https://getabrainscan.com/ KetoFLEX 12/3: https://www.trifectanutrition.com/apollohealthpartner Connect with me! Website Instagram Facebook YouTube   This episode is sponsored by Professional Co-op®, where clinicians gain exceptional access to industry-leading lab services without the hefty price tag—since 2001, they've been redefining what efficient, patient-focused support looks like. Imagine no hidden fees, no minimums, and only paying for completed tests. Experience lab services that not only meet but also exceed your expectations. Join the co-op trusted by countless licensed clinicians nationwide. Visit www.professionalco-op.com to learn more! This episode is also made possible by Functional Medicine University. FMU is a fully online, self-paced training program in functional medicine, founded in 2006 by Dr. Ron Grisanti. With students in all 50 U.S. states and 68 countries globally, FMU has become a cornerstone in advanced clinical education for healthcare practitioners. The curriculum is led by Dr. Grisanti, alongside contributions from over 70 distinguished medical experts on FMU's advisory board. Graduates earn the prestigious Certified Functional Medicine Practitioner (CFMP®) credential upon completion. FMU is also a nationally approved provider of continuing education for a wide range of licensed professionals, including MDs, DCs, DOs, NDs, acupuncturists, PAs, NPs, nurses, dietitians, pharmacists, and dentists. Whether you're looking to expand your clinical knowledge or bring a functional approach to your practice, FMU offers the tools, guidance, and certification to help you thrive. Visit www.functionalmedicineuniversity.com to learn more!

On this week's installment of the Real Health Podcast, Dr. Reed Jarvis talks about what neurodegeneration is defined as and what are the best ways to combat it decades in advance. All of this and more on the Real Health Podcast!

The blood-brain barrier (BBB)

There is an important role for cost-effective clinical biomarkers in the diagnosis of Parkinson's disease. Dr. Eduardo de Pablo-Fernández and Dr. Cecilia Tremblay discuss how accurate hyposmia and REM sleep behavior disorder can predict Lewy pathology in a non-selected population using data from the Arizona clinicopathological study on Aging and Neurodegeneration. Read the article.

CT scan accidentally reveals calcium deposits where they don't belong; Dispelling the myth that hunter-gatherers get more sleep than Westerners; Blue light exposure at night impairs sleep—but morning exposure improves it; When normal B12 levels aren't enough; NT Factor vs. urolithin A (Mitopure®️) for mitochondria; Alternatives to PPIs for Barrett's Esophagus; Topical—not oral—melatonin for skin rejuvenation. 

In part two of this two-part series, Dr. Vikram Karnik and Dr. Lorraine Kalia discuss the preclinical data and epidemiological data that led us to the phase three study on exenatide. Show reference: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00161-8/abstract  

Dr. Vikram Karnik talks with Dr. Lorraine V. Kalia about the potential role of GLP-1 receptor agonists in neurodegenerative diseases, the current state of research, preclinical evidence, and future directions for GLP-1 agonists. Read the related article in The Lancet. Disclosures can be found at Neurology.org.  

In part one of this two-part series, Dr. Vikram Karnik and Dr. Lorraine Kalia discuss recent clinical trials on exenatide as a disease-modifying therapy for Parkinson disease. Show reference: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00161-8/abstract 

In this episode of the Unreasonable Health Podcast, Cade Archibald kicks off The Ageless Brain five-part series, diving into the science of neuroinflammation, cognitive decline, and brain regeneration.He explores the role of peptides like Semax and Selank in reducing inflammation and enhancing neuroplasticity, alongside nootropics and lifestyle interventions that support brain health. Cade also introduces the NeuroCatch test, a cutting-edge tool for assessing cognitive function, and challenges listeners to engage in activities that boost neuroplasticity. Tune in to discover how to optimize your brain for longevity and peak performance!To optimize your brain, check us out! https://acueastwest.com/

This episode of Naked Neuroscience is co-published on the Naked Scientists Podcast. James Tytko examines one of the largest causes of disability amongst the young: multiple sclerosis. We hear from Lara Kingsman who is living with MS, doctors at the University of Cambridge take us inside the brain to help guide interventions, and the MS Society tell us about their innovative drug trial in collaboration with UCL to help find new treatments... Like this podcast? Please help us by supporting the Naked Scientists

Send us a textShort Summary: The complexities of neurodegenerative disease, particularly Alzheimer's, environmental influences like glyphosate, and the crucial role of nutrients like choline, with actionable insights into brain health management.About the guest: Dr. Ramon Valazquez is an Assistant Professor at Arizona State University, leading a research lab at the Neurodegenerative Disease Research Center. His work focuses on environmental factors related to Alzheimer's and other dementias, alongside developing therapeutic strategies.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and to everyone on YouTube. Partial versions are available elsewhere. Full transcript and other information on Substack.Episode Summary: Dr. Ramon Velazquez explores neurodegenerative disease, with a deep dive into Alzheimer's, its pathophysiology including amyloid beta plaques and tau pathology. It examines the controversy around these proteins' roles in disease progression, the influence of environmental toxins like glyphosate on brain health, and the preventive potential of nutritional interventions, particularly choline.Key Takeaways:Neurodegenerative Disease Basics: Alzheimer's disease involves both amyloid beta plaques and tau tangles, with tau pathology more closely linked to clinical symptoms.Environmental Impact: Glyphosate, a common herbicide, can cross into the brain, potentially exacerbating neurodegenerative pathways through inflammation.Choline: Essential for brain function and fat metabolism, it's often deficient in diets, particularly plant-based ones. Adequate intake might prevent or mitigate cognitive decline and related diseases.Preventive Measures: Early nutritional intervention, like maintaining choline levels, could be vital for preventing neurodegenerative diseases. However, once symptoms are present, such interventions might not reverse existing pathology.Related episode:M&M #145: Epigenetics, HormonesSupport the showAll episodes, show notes, transcripts, etc. at the M&M Substack Affiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Readwise: Organize and share what you read. Use your phone's link. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription. MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. For all the ways you can support my efforts

Harness Therapeutics' CEO talked to In Vivo about the company's scientific strategy, and its plans for expansion and partnering in the neurodegeneration space.

Is Your Microbiome Sabotaging Your Health? I am joined by Kiran Krishnan as we delve into the fascinating world of gut health and probiotics! Kiran explains the crucial roles of different types of bacteria in maintaining gut health, the pitfalls of common probiotic supplements, and introduces us to spore-based probiotics and psychobiotics. He offers actionable insights into improving gut health through diet, exercise, and the right supplements.  Kiran Krishnan is renowned research microbiologist and an expert in the human microbiome. With over two decades of experience in the field and has been at the forefront of groundbreaking research, focusing on the critical role our gut microbiome plays in overall health. Visit https://justthrivehealth.com and use code NAT20 for a discount. What We Discuss Understanding Gut Health and the Human Microbiome 00:27 The Role of Microbes in Digestive Health 01:11 Microbiome Diversity and Its Impact on Health 03:34 Challenges with Gut Testing Kits 04:23 Functional Redundancy in the Microbiome 05:29 Balancing Microbial Populations for Optimal Health 08:40 The Importance of Microbiome Diversity 10:10 Misconceptions About Pathogens in the Gut 11:23  The Impact of Modern Lifestyle on Gut Health 19:26 The Gut-Brain Connection 27:04 Inflammation and the HPA Axis 32:06 Neurodegeneration and Protein Misfolding 32:55 Impact of Endotoxins on Neurotransmitters 34:27 Gut-Brain-Liver Axis and Energy Balance 35:33 The Role of Sleep and BDNF in Brain Repair 40:44 Rising Prevalence of Neurological Disorders 41:51 Probiotics and Gut Health Solutions 43:57 The Importance of Fiber 54:04 Conclusion and Product Recommendations 01:00:48   Thank you to our sponsors for making this episode possible: Zona Health: Visit https://www.zona.com/ and use code NAT24 to save $100 on the purchase of a Zona Plus device Element Health Supply: Use code Lonevity when shopping at https://elementhealthsupply.com/discount/Longevity to save on your orders.    SiPhox: Visit http://SiPhoxhealth.com/nat and save on your test.    Find more from Kiran Krishnan & Just Thrive: Website: https://justthrivehealth.com  Instagram: https://www.instagram.com/justthrivehealth/    Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ  Join Nat's Membership Community: https://www.natniddam.com/bsp-community  Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0  Instagram: https://www.instagram.com/nathalieniddam/  Website: www.NatNiddam.com    Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance    Key Take Aways: Gut health significantly impacts overall well-being, including mental health, cognitive function, and systemic health. Maintaining a balance of gut bacteria, which in turn supports metabolic, immune, and neurological health. Consuming a diverse diet rich in fibers helps promote this diversity. Consistent dietary and lifestyle changes are important for maintaining a healthy gut. Prebiotics are as important as probiotics feed beneficial bacteria and support a healthy microbiome.

Guest Michael Greicius is an authority on Alzheimer's disease. He makes the case that while effective treatments have remained elusive, there are high hopes for new approaches that target tau proteins in the brain associated with the disease. In the meantime, to reduce Alzheimer's risk stay active, eat well, and manage circulatory risks, but skip genetic testing for now until better treatments emerge, Greicius tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile:  Michael GreiciusConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Michael Greicius, a professor of neurology and neurological sciences at Stanford University.(00:02:12) Understanding Alzheimer's DiseaseThe roles of amyloid and tau proteins in Alzheimer's disease.(00:04:53) Challenges in Developing TreatmentsThe multiple hurdles in creating Alzheimer's therapies.(00:09:07) Current Alzheimer's DrugsThe controversies and limitations of recently approved drugs.(00:10:23) Amyloid Plaques and Their ImpactWhy removing amyloid plaques hasn't improved patient outcomes.(00:14:29) Problems with Alzheimer's TrialsThe disconnect between amyloid removal and patient outcomes.(00:18:03) Functional Unblinding and Trial BiasHow functional unblinding affects trial results and drug evaluations.(00:23:51) The Potential of Targeting TauNew breakthroughs in targeting tau protein for Alzheimer's.(00:26:35) The Future of PreventionPotential preemptive treatments for Alzheimer's and their administration.(00:29:19) Lifestyle and Risk ReductionRecommendations for reducing risk of Alzheimer's disease.(00:31:43) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

In this episode of the Health Detective Podcast by Functional Diagnostic Nutrition, the focus is on the cGAS-STING signaling pathway and its role in driving age-related inflammation and neurodegeneration. Dr. Gonshor delves into recent research revealing how this pathway, usually responsible for immune defense, contributes to chronic inflammation and functional decline during aging.  Where to find more about FDN: fdntraining.com/resources.   

Curious about the secret to staying young? Rob Signer shares insights into how our bodies age, focusing on the role of stem cells and a critical protein called HSF1 that helps them cope with stress. Signer explores the delicate balance of keeping these cells healthy without increasing cancer risk and highlighted some promising progress in enhancing the cells' ability to manage waste. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39980]

Curious about the secret to staying young? Rob Signer shares insights into how our bodies age, focusing on the role of stem cells and a critical protein called HSF1 that helps them cope with stress. Signer explores the delicate balance of keeping these cells healthy without increasing cancer risk and highlighted some promising progress in enhancing the cells' ability to manage waste. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39980]

Curious about the secret to staying young? Rob Signer shares insights into how our bodies age, focusing on the role of stem cells and a critical protein called HSF1 that helps them cope with stress. Signer explores the delicate balance of keeping these cells healthy without increasing cancer risk and highlighted some promising progress in enhancing the cells' ability to manage waste. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39980]

In this episode, we dive into the role of microglial cells, the brain's resident immune defenders, and how their chronic activation at the cellular level contributes to neurodegeneration. We'll explore the cellular mechanisms behind microglial activation, including the involvement of P2Y12 receptors and the release of pro-inflammatory cytokines like IL-1β and TNF-α. Additionally, we'll discuss how everyday environmental toxins and stressors can trigger long-term microglial activity, potentially increasing the risk of conditions like Alzheimer's. Topics: 1. Introduction - Overview: Microglia and neurodegeneration. - Environmental toxins affecting microglia. 2. Brain and Microglial Overview - Brain has neurons and glial cells. - Microglia are the brain's immune cells. - Roles: Immune defense, synaptic pruning, neuroprotection. 3. Microglial Immune Function - Constantly monitor for infection and damage. - Activated microglia perform phagocytosis. - Clear debris and maintain brain health. 4. Cellular Mechanisms of Activation - P2Y12 receptors respond to ATP/ADP. - Microglia shift from resting to activated. - Activated microglia are highly phagocytic. 5. Role in Synaptic Pruning - Microglia help in synaptic pruning. - Remove weak synapses for efficient brain circuits. 6. Microglia in Neurodegeneration - Chronic activation leads to inflammation. - Release of cytokines like IL-1β, TNF-α, IL-6. - Contributes to Alzheimer's, Parkinson's. - MHC molecules 7. Environmental Toxins and Activation - Mycotoxins cross BBB and activate microglia - Heavy metals like lead, aluminum affect neurons - Pesticides/herbicides linked to Parkinson's risk 8. Other Factors Activating Microglia - Industrial chemicals, BPA - Artificial additives, alcohol - Chronic stress 9. Conclusion - Recap: Microglial functions and overactivation. - Lifestyle factors influence microglial health. Thank you to our episode sponsors: 1. Check out ⁠⁠⁠⁠⁠⁠⁠Daily Nouri⁠⁠⁠⁠⁠⁠⁠ and use code ⁠⁠⁠⁠⁠⁠⁠CHLOE20⁠⁠⁠⁠⁠⁠⁠ for 20% off your order. 2. Check out the TruAge ⁠Biological Age Test⁠ from ⁠TruMe Labs⁠. Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

In this episode, we have the privilege of speaking with Dr. Michael Lewis, renowned expert in brain health and traumatic brain injury (TBI), and author of the groundbreaking book, When Brains Collide. Dr. Lewis is the founder of the Brain Health Education and Research Institute and BrainCARE. With a military background and extensive experience in traumatic brain injuries, Dr. Lewis has dedicated his career to exploring how omega-3 fish oils can play a vital role in preventing and recovering from concussions, TBI, stroke, and neurodegenerative diseases. Key Discussion Points 1. The Role of Omega-3 Fish Oils in Brain Health Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA), the primary omega-3 fatty acids found in fish oil, are crucial for maintaining brain structure and function. Omega-3s are anti-inflammatory and neuroprotective, making them vital in protecting the brain from injury and supporting recovery. 2. High-Dose Omega-3 Fish Oil for Concussions and Traumatic Brain Injury (TBI) Dr. Lewis emphasizes how high-dose fish oil can help mitigate damage following a concussion or TBI. Dosing Protocols: In acute brain injury cases, Dr. Lewis recommends significantly higher doses of fish oil (e.g., up to 3-9 grams of combined DHA and EPA per day) to reduce inflammation, promote healing, and restore brain cell membrane integrity. Case studies demonstrate remarkable improvements in TBI patients, including quicker recovery times, reduced brain fog, and restored cognitive function. 3. Fish Oils for Neurodegeneration and Stroke Prevention Regular intake of omega-3s is shown to be effective in reducing the risk of neurodegenerative diseases like Alzheimer's and Parkinson's. Omega-3s help prevent stroke by reducing blood clot formation, improving vascular health, and lowering inflammation in brain tissues. Dr. Lewis advocates for omega-3s as part of a preventive strategy, particularly for aging individuals at higher risk of neurodegenerative conditions. 4. Using Omega-3s as Preventive Medicine Consistent omega-3 supplementation is not just for recovery—it's crucial for maintaining optimal brain health. Athletes, military personnel, and individuals at risk for head trauma should use omega-3s proactively to strengthen their brain's resilience to injury. Preventative Dosing: Dr. Lewis suggests a daily intake of at least 2-3 grams of DHA and EPA combined for ongoing brain health and injury prevention. 5. How to Choose a High-Quality Fish Oil Dr. Lewis explains the criteria for identifying a high-quality fish oil supplement: Purity: Free from contaminants like heavy metals and toxins. Potency: Look for a high concentration of DHA and EPA. Stability: Avoid fish oils that oxidize easily, as rancid oils can be harmful. Sourcing: Prefer fish oils sourced from wild-caught, sustainably harvested fish. Importance of third-party testing to ensure the product is safe and effective. 6. Personal Stories and Case Studies Dr. Lewis shares inspiring stories of patients and athletes who have successfully used omega-3 therapy to recover from brain injuries. Examples include a football player who recovered from multiple concussions and a stroke survivor who regained cognitive function with high-dose omega-3 supplementation. 7. How to Use Omega-3s After Brain Injury Immediate supplementation following a brain injury can make a significant difference in recovery outcomes. The sooner omega-3s are introduced post-injury, the better. Dr. Lewis provides insight into the timing and administration of omega-3 supplements during the acute phase of brain injury treatment. Recommended Resources: Dr. Michael Lewis's Website: Brain Health Education and Research Institute: http://www.brainhealtheducation.org/ BrainCARE: BrainCARE Center   When Brains Collide Book Join us for this enlightening discussion on the powerful benefits of omega-3 fish oils for brain protection, recovery, and overall health. Dr. Michael Lewis's pioneering work is transforming how we approach brain injuries and neurodegeneration, highlighting the critical role that nutrition and supplementation play in maintaining cognitive vitality. Tune in to learn how you can harness the power of omega-3s for your brain health and optimize your recovery from injury or disease.   BIO Michael Lewis, MD, MPH, MBA, FACPM, FACN, is a proven leader and expert in the treatment and management of concussions and brain injuries. He also applies his holistic approach to Men's Health and outpatient orthopedics. Upon retiring as a Colonel in the U.S. Army, he founded the nonprofit Brain Health Education and Research Institute and entered private practice focusing on helping patients with chronic concussion issues. His pioneering work in the military and since has helped thousands of people around the world and he is regularly featured in the media, radio, podcasts, webinars, scientific conferences, and television. A lifelong athlete, Dr. Lewis serves on the Pop Warner Youth Football Medical Advisory Board and Board of Directors of National Collegiate Rugby where is also the head of the Medical and Safety Committee. Dr. Lewis is the author of When Brains Collide: What Every Athlete and Parent Should Know About the Prevention and Treatment of Concussions and Head Injuries. He is a graduate of the U.S. Military Academy at West Point and Tulane University School of Medicine. He is board- certified and a Fellow of the American College of  Preventive Medicine and American College of Nutrition. He completed post-graduate training at Walter Reed Army Medical Center, Johns Hopkins University, and Walter Reed Army Institute of Research.   Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with:  Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen,  intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. Testing Options Comprehensive Thyroid testing DUTCH Hormone testing Adrenal Testing Organic Acid Testing Microbiome Testing Cell Blueprint Testing Epigenetics Testing DNA testing Basic Blood Test analysis Heavy Metals  Nutristat Omega 3 to 6 status and more  Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine . She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the  challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa    Join our Patron program and support the show Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission.  Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to  Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to  https://www.buymeacoffee.com/LisaT to donate $3   Lisa's Anti-Aging and Longevity Supplements  Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world.  This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that's what it's in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life.   Subscribe to our popular Youtube channel  with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube   Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge"  Check them all out at  https://shop.lisatamati.com/collections/books   Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here:    Use code "tamati" at checkout to get a 10% discount on any of their devices.   Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38   Or Try Vielights' advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off     Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts.  To pushing the limits, Lisa and team  

In the past few years, Big Pharma has released not one, but three new treatments for Alzheimer's disease. Aducanemab (2021), Lecanemab (2023), and Donanemab (2024), are the first treatments to effectively clear the brain of amyloid plaques — the sticky protein clumps whose build-up in the brain has defined the disease for decades. The problem? They may not help patients at all.Today's guest, Stanford neurologist Mike Greicius, considers the new amyloid-clearing drugs a major disappointment — and worse, says they likely do more harm than good for patients.Despite this critique, Greicius, thinks that the next few years will be an exciting time for novel Alzheimer's therapies, as growing biological understanding of Alzheimer's risk and resilience bear fruit with promising new approaches to treatment.Learn More:Greicius is the Iqbal Farrukh and Asad Jamal Professor of Neurology and Neurological Sciences at Stanford Medicine, and a member of the Knight Initiative for Brain Resilience and Alzheimer's Disease Research Center at Stanford University.Amyloid Drug Skepticism:Substantial Doubt Remains about the Efficacy of Anti-Amyloid Antibodies(Commentary, Journal of Alzheimer's Disease, 2024)New Drug Approved for Early Alzheimer's (New York Times, 2024)Alzheimer's drug adoption in US slowed by doctors' skepticism (Reuters, 2024)One step back: Why the new Alzheimer's plaque-attack drugs don't work (Stanford Medicine Scope Blog, 2024)Alzheimer's Genetics Research:Knight-funded research uncovers gene mutations that may prevent Alzheimer's Disease (Knight Initiative for Brain Resilience, 2024)Why is a common gene variant bad for your brain? (Stanford Medicine Magazine, 2024)Scientists find genetic Alzheimer's risk factor tied to African ancestry (Stanford Medicine, 2023)Episode CreditsThis episode was produced by Michael Osborne, with production assistance by Morgan Honaker, and hosted by Nicholas Weiler. Art by Aimee Garza.Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

*A disclaimer that there will be discussions of self harm in this episode* In 2003, Chris Nowinski found himself in a WWE wrestling ring, concussed and not remembering where he was or how he was supposed to finish the match. This would be a pivotal moment not just in his life but for an entire field of research on a neurodegenerative disease long known to exist but poorly defined and even censored: chronic traumatic encephalopathy or CTE. There's evidence that people knew about CTE — which went by names like “punch drunk” — starting in the 1920s, but it wasn't until the 2000s, when American football players began being diagnosed with CTE post-mortem, that the disease started gaining public traction. Many of those football players, including Andre Waters, had died by suicide. Chris, now a behavioral neuroscientist and the co-founder and CEO of the Concussion Legacy Foundation, pushed to get the brains of Waters and other athletes tested, and began spreading awareness and putting pressure on organizations like the NFL to acknowledge the devastation this disease can bring to athletes and their families.Today on the show we will cover what's known about CTE and how to prevent it, and how researchers are trying to find ways of diagnosing it in people who are still alive and working to find treatments.Here are some good CTE resources:https://concussionfoundation.org/CTE-resources/support https://www.bu.edu/cte/resources/resources-for-families/Send us your science stories/factoids/news for a chance to be featured on an upcoming Tiny Show and Tell Us episode and to be entered to win a Tiny Matters coffee mug! And, while you're at it, subscribe to our newsletter at bit.ly/tinymattersnewsletter.Links to the Tiny Show & Tell stories are here and here. All Tiny Matters transcripts and references are available here.

In today's episode of The Root Cause Medicine Podcast, we navigate the importance of brain health and preventing cognitive decline with Louisa Nicola. You'll hear us discuss: 1. How women in their 30s and 40s can prevent Alzheimer's 2. Why exercise is the best preventive tool against Alzheimer's disease 3. The surprising benefits of resistance training for your brain health 4. Nutrition insights for enhancing brain health 5. Why the best thing for a healthy aging brain is social connections Louisa is a neurophysiologist and human performance coach. She is the Founder of Neuro Athletics, a consulting firm that works with top athletes worldwide, leveraging EEG scans, lab tests, and cognitive assessments to optimize performance. Louisa's insights delve deep into the minds of elite NBA and MLB stars. Additionally, she serves on the board of Momentous, Tonal, and Klora. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

On today's solo episode....Neurodegeneration and brain aging affect millions worldwide, with numbers expected to triple by 2050. While pharmaceuticals offer limited solutions, lifestyle choices, especially exercise and diet, are vital for brain health.Study 1: Chronic Inflammation and Cognitive Performance The CARDIA study tracked inflammation in young adults and found chronic inflammation can impair midlife cognitive performance. Participants with high CRP levels were significantly more likely to have poor processing speed and executive function. Early management of inflammation is crucial for cognitive health.Study 2: Smoking and Cognitive Decline A Nature Communications study of 32,000 adults revealed smoking accelerates cognitive decline by up to 85% over 10 years. Smokers who adopted healthy behaviors like exercise and socializing had cognitive decline rates similar to non-smokers, highlighting the importance of quitting smoking and healthy living.Study 3: Diets Rich in Omega-3s and Antioxidants A study found older adults with diets rich in omega-3s, antioxidants, and vitamins show slower brain aging and better cognitive function. Nutrients like alpha-linolenic acid, EPA, lutein, zeaxanthin, vitamin E, and choline are crucial for brain health, emphasizing the role of diet in cognitive maintenance.Sponsors:ZocDoc- Use code NEURO - https://www.zocdoc.com/neuroBioProtein Technology - Use code LOUISA to save 10% - https://www.bioproteintech.com/shop/biopro-plus-cortisleepStudies:1. Inflammation2. Smoking3. Diet & Brain Health#Alzheimersdisease  #dementia #brainhealth #diet #omega3 #antioxidantsThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner.

In this episode, my guest is Dr. Gary Steinberg, MD, PhD, a neurosurgeon and a professor of neurosciences, neurosurgery, and neurology at Stanford University School of Medicine. We discuss brain health and brain injuries, including concussion, traumatic brain injury (TBI), stroke, aneurysm, and transient ischemic attacks (TIA). We discuss key and lesser-known risk factors for brain health and explain how certain treatments and medications can improve brain health and cognitive function. We also cover novel mechanisms to improve recovery after concussions and brain injury, including the use of stem cells, temperature (mild hypothermia), and vagus nerve stimulation. Dr. Steinberg also describes new advances in neurosurgery and minimally invasive brain augmentation. This episode ought to be of interest to anyone seeking actionable tools to improve their brain health and for those seeking to improve recovery after a brain injury such as concussion, stroke, aneurysm, or TBI. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman AeroPress: https://aeropress.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Gary Steinberg 00:01:44 Sponsors: Eight Sleep, ROKA & AeroPress; Subscribe on YouTube, Spotify & Apple 00:06:16 Stroke, Hemorrhage & Blood Clot 00:10:25 Blood Clots & Risk Factors, Medications, Smoking, Cholesterol 00:16:19 Heart & Brain Health; Neurosurgery & Brain Function 00:23:27 Current Technology & Neurosurgery, Minimally Invasive Techniques 00:28:13 Transient Ischemic Attacks (TIA); Spinal Cord Strokes 00:33:23 Stroke Risk: Alcohol, Cocaine & Other Drugs 00:38:24 Sponsor: AG1 00:39:55 Traumatic Brain Injury (TBI), Concussion: Sports, Testing & Recovery 00:46:45 Statins; TBI & Aspirin; Caffeine & Stroke Risk 00:48:31 Exploratory MRI: Benefits & Risks 00:51:53 Blood Pressure, Lifestyle Factors; Tool: Feeling Faint, Hydration; Sleep 00:59:52 Sponsor: LMNT 01:01:27 Chiropractic Neck Adjustment & Arterial Obstruction; Inversion Tables 01:05:16 Kids, Tackle Football, Soccer, Boxing; Mild Concussion 01:10:49 Nerve Regeneration, Stem Cells, Stroke Recovery 01:17:36 Stem Cells, Immune System, Activity 01:21:27 Injury & Recovery, Restraint Therapy 01:23:46 Neuroprotection After Injury; Mild Hypothermia 01:34:59 Platelet-Rich Plasma (PRP), Stem Cell Therapy 01:42:27 Scientific Advancements & Clinical Translation, FDA & Industry 01:47:40 Vagal Stimulation 01:53:17 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer

In this episode, my guest is Dr. E.J. Chichilnisky, Ph.D., professor of neurosurgery and ophthalmology at Stanford University, studying how we see and use that information to build artificial eyes to restore vision to people who are blind. We discuss how understanding the retina (the light-sensing brain tissue that lines the back of our eyes) is critical to knowing how our brain works more generally. We discuss brain augmentation with biologically informed prostheses, robotics, and AI and what this means for medicine and humanity. We also discuss E.J.'s unique journey into neuroscience and how changing fields multiple times, combined with some wandering, taught him how to guide his decision-making in all realms of life. This episode ought to be of interest to anyone interested in learning how the brain works, from a world-class neuroscientist to the future of brain therapeutics and to those seeking inspiration and tools for navigating their own professional and life journey. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman  ROKA: https://roka.com/huberman  BetterHelp: https://betterhelp.com/huberman  InsideTracker: https://insidetracker.com/huberman Momentous: https://livemomentous.com/huberman Timestamps (00:00:00) Dr. E.J. Chichilnisky (00:02:31) Sponsors: Eight Sleep, ROKA & BetterHelp (00:06:06) Vision & Brain; Retina (00:11:23) Retina & Visual Processing (00:18:37) Vision in Humans & Other Animals, Color (00:23:01) Studying the Human Retina (00:29:48) Sponsor: AG1 (00:31:16) Cell Types (00:36:00) Determining Cell Function in Retina (00:43:39) Retinal Cell Types & Stimuli (00:49:27) Retinal Prostheses, Implants (01:00:25) Artificial Retina, Augmenting Vision (01:06:05) Sponsor: InsideTracker (01:07:12) Neuroengineering, Neuroaugmentation & Specificity (01:17:01) Building a Smart Device, AI (01:20:02) Neural Prosthesis, Paralysis; Specificity (01:25:21) Neurodegeneration; Adult Neuroplasticity; Implant Specificity (01:34:00) Career Journey, Music & Dance, Neuroscience  (01:42:55) Self-Understanding, Coffee; Self-Love, Mediation & Yoga (01:47:50) Body Signals & Decisions; Beauty (01:57:49) Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter Disclaimer