Talkin Immunology with BioLegend

In this latest podcast, we tackle the resurgence of Measles, vaccinations, and common anti-vaccination myths!Note regarding our talk on the polio vaccine: Following its mass production in 1955, certain pharmaceutical companies failed to properly inactivate the Salk vaccine, leading to over 250 reported cases of paralysis. Salk’s inactivated polio vaccine was the first developed, followed by the oral polio vaccine (OPV). OPV remained in use in the US until 1999 where it was replaced with an inactivated, injectable vaccine. However, OPV is still used in other countries around the world. Topics Common vaccination myths WHO's ten threats to global health in 2019 Teen secretly gets vaccinated, speaks to Senate Unvaccinated teen sues school for limiting his activity Facebook to ban anti-vaxx ads in new push against 'vaccine hoaxes' Measles returns to Costa Rica thanks to unvaccinated family Anti-Vaxx mom asks how she can protect her 3 year old from Measles outbreak Study on 657,461 children finds no link between autism and vaccines Keywords: vaccines, measles, immunology, anti-vaxxers, autism, Andrew Wakefield, myths, science, Ethan Lindenberger, kale, global health, chickenpox

In our return to the podcast, we discuss the first immortal cell line, HeLa cells, and the controversial circumstances of how they were obtained from Henrietta Lacks. Topics The Controversy Over HeLa Cells The Henrietta Lacks Foundation The Legacy of Henrietta Lacks (Johns Hopkins Medicine) Johns Hopkins to name research building after Henrietta Lacks Moore v. Regents of the University of California Dat Tran and Lick-A-Bubble Harry Potter Spoilers (15:32-15:50) Keywords: Henrietta Lacks, podcast, HeLa cells, cell line, telomeres, telomerase, polio, senescence, Helen Lane, cancer, Johns Hopkins, George Otto Gey, The Immortal Life of Henrietta Lacks, Rebecca Skloot, John Moore, David Golde

Check out our new podcast to learn about fast-travel for cells in the skull, gut bacteria influence on the body, and whether we’re starting a fantasy scientist draft league! Topics Microtunnels in the Skull (2:11-10:04) Russia Is Opening A "Jurassic Park-Style" Research Lab (10:05-19:45) The Fantasy Scientist Draft (22:05-26:25) Gut Bacteria, Bullying, Junk Food, and You! (26:26-42:20) God of War Shout-out (46:52) Successful Placebo Pills (47:48-52:20) Keywords: Immunology, podcast, brain, skull, marrow, microtunnels, extinction, Jurassic park, dodo, wooly mammoth, dna, fantasy football, microbiota, gut bacteria, memory, bullying, junk food, diet, psychobiotics, elderberries, Placebo Effect, honest placebo, IBD, inflammatory bowel disease  

In our newest podcast, we talk about autoimmune diseases linked to the Kissing Disease, concerns over the emerging Nipah Virus, and how fetal immunity may be causing babies to be born early. Topics Epstein-Barr Virus and Autoimmunity (2:20-12:00) Nipah Virus Outbreaks (12:01-20:35) Bacteria Coats itself with IgA for Protection (23:23-32:23) Out of Whack Fetal Immune Systems Prompt Preterm Labor (35:45-43:33) Keywords: autoimmunity, kissing disease, mononucleosis, Nipah Virus, herpes, Epstein-barr virus, cancer, bats, reservoir, Bacteroides fragilis, IgA, gut, mucosa, bacteria, pregnancy, premature birth, fetal immunity, preterm  

In our new podcast, we look at the science behind popular video game franchises like Resident Evil, Final Fantasy VII, and The Last of Us! Topics Final Fantasy VII (Podcast from 2:35-14:20) Resident Evil (Podcast from 14:20-26:50) The Last of Us (Podcast from 31:50 to 44:00; Spoilers from 41:20 to 42:18) Viruses in the Resident Evil Series The Last of Us Part II Stages of Infection in the Last of Us Cordyceps: Attack of the Killer Fungi-Planet Earth with David Attenborough Intro music “The Pirate and the Dancer” by artist Rolemusic at the Free Music Archive. Keywords: video games, science, podcast, resident evil, final fantasy VII, Jenova, CRISPR, gene splicing, Sephiroth, virus, T-virus, mitochondria, retrovirus, reverse transcriptase, Ebola, Atari, playstation, The Last of Us, Cordyceps, fungus  

In our new podcast, we welcome guest Jason Lehmann to discuss his work with malaria, his new LEGENDplex™ promotion at BioLegend, and how class timing can influence your grades. Topics The Undersea LEGENDplex™ Adventure LEGENDplex™ Plush Plexy Promotion New human antibody prevents malaria in mice Class time affects grades School starts too early according to CDC Keywords: malaria, Jason Lehmann, mosquito, parasite, infectious disease, plasmodium falciparum, vivax, Haiti, cytokines, multiplexing, LEGENDplex, CIS43, social jetlag, Beatles, octopus  

In our new podcast, we discuss the life of Stephen Hawking, new studies to extend lifespans, and how scaffolding in cancer vaccines promotes dendritic cell responses. Topics In remembrance of Stephen Hawking SEC press release on Theranos and Elizabeth Holmes Could Rapamycin help humans live longer? High-Fiber Diet Shifts Gut Microbes, Lowering Blood Sugar in Diabetics Personal cancer vaccines show promise Keywords: Stephen Hawking, A Brief History of Time, ALS, Amyotrophic Lateral Sclerosis, Theranos, Elizabeth Holmes, rapaymycin, microbiome, fiber, gut bacteria, type 2 diabetes, cancer vaccine  

In our new podcast, we welcome guest Jonathan Deane from GNF to discuss both the difficult and rewarding properties of drug discovery and research. The thoughts and opinions of our guest, Jonathan Deane, are his own personal reflections and do not necessarily reflect the opinions or positions of The Genomics Institute of the Novartis Research Foundation (GNF). Topics The Genomics Institute of the Novartis Research Foundation Jonathan Deane’s TLR7 article and painting The American Association of Immunologists Advocacy Center The Good and Bad of Generic Drugs Pricing Pharmaceuticals, Parts 1 and 2 Giving a Scientific Talk, Parts 1 and 2 Keywords: Jonathan Deane, drug discovery, podcast, BioLegend, GNF, genomics institute of the Novartis research foundation, pharmaceutical, toastmasters, innate immunity, TLR7, clinical, American Association of Immunologists, lupus  

As we pass 100,000 downloads, we reminisce about our favorite topics, guests, and podcasts of the past five years. Topics Emerging Technologies in BioTech Podcast with John Ransom GMOs, Organic Food and Science Myths Podcast with Lauren Uhde, the Biology Babe Global Health Science Podcast with Jessica Taaffe The Post-Doc Experience Podcast with Francesca Soncin Interview with William Golde on T Suppressor Cells Keywords: podcast, anniversary, T suppressor cells, Tregs, grad students, post-docs  

In our first podcast of the new year, we talk about the tough 2018 flu season, CRISPR immunity, and the effects of diet on immunity. Topics CRISPR may be ineffective in human trials due to immunity First US CRISPR trials will target cancer Why this year’s flu season is so much worse in the US, UK and Australia How are subtypes of the flu named? Is the man-flu real? Man ruptures throat after holding in sneeze Fast food may make your immune system more aggressive High salt diet produces dementia in mice Keywords: influenza, H3N2, CRISPR, fast food, salt, vaccines, man flu, Cas9, immunity, BioLegend, podcast, immunology, diet

In our latest podcast, we speak with special guest, Dr. Vijay Kuchroo, covering cancer research, innate lymphoid cells, and the integration of immune cells into multiple systems. Topics The Kuchroo Laboratory Immune Checkpoints Innate Lymphoid Cells Sean Parker and Cancer Immunotherapy Immuno-Oncology Research Tools Keywords: Dr. Vijay Kuchroo, Harvard, Tregs, Th17, ILC, innate lymphoid cells, tumor cells, immune checkpoints, TIGIT, PD-1, cancer, GWAS, synapses  

We discuss a new source of platelets, macrophages maintaining heartbeats, and the regenerative power of axolotls. Topics Anti-doping agency bans gene editing Lungs major source of platelets Macrophages help maintain a steady heartbeat Macrophages may also be key to heart regeneration in axolotls Axolotls are Masters of Regeneration Tattoo nanoparticles make their way to lymph nodes Keywords: axolotl, regeneration, macrophage, heartbeat, cardiomyocyte, tattoo, lymph node, platelets, lungs, CRISPR, nanoparticles

We welcome graphic designers and artists at BioLegend and get their perspective on how they meld art with science. Topics Amanda Kwieraga Society6 Amanda Kwieraga Webpage Cell Life Imaging Competition Colossal: Art, Design, and Visual Culture The Department of Art as Applied to Medicine at Johns Hopkins Print Ad Library Wallpaper Art Keywords: art, science, BioLegend, posters, graphics, podcast, graphic design, illustrations  

We discuss an innovative tool for Type 1 Diabetes monitoring, a Star Wars publication, and new STEM badges for Girl Scouts. Topics This woman designed-and texts-her own pancreas Novartis CAR-T cell therapy CTL019 approved by FDA to treat pediatric, young adults with B-cell acute lymphoblastic leukemia We are all mutants CRISPR restores muscle function in mice Predatory journals hit by 'Star Wars' sting Girl Scouts add 23 STEM badges Most of human genome nonfunctional Keywords: Type 1 Diabetes, insulin pump, glucose monitor, genetics, environment, Dana Lewis, CAR T Cell Therapy, CTL019, Novartis, mutations, BRCA, CRISPR, Star Wars, journals, midichlorians, girl scouts, STEM  

We return to the Talkin' Immunology Podcast with guest Lenny Teytelman to discuss his website, protocols.io, and the challenges of protocol reproducibility, journal paywalls, and more. Topics Protocols.io BioLegend supports The Reproducibility Initiative BioLegend protocols Why I, a founder of PLOS, am forsaking open access Cuckoo for Cocoa Puffs publication Keywords: Lenny Teytelman, protocols, reproducibility initiative, journals, paywalls, troubleshooting, reagents, antibodies, protocols.io, PLOS, Michael Eisen  

This latest podcast covers interesting animal-related news, including cannibalistic hamsters and the nerdy names scientists have given to newly discovered species. Topics Corn turns wild hamsters into cannibals Bathing chicken eggs in light makes for calmer chickens Fistulated Cows Malaria molecule makes blood alluring to mosquitos New amoeba named after Gandalf New crab named after Severus Snape and other nerdy animal names Keywords: animals, corn, niacin, hamsters, chickens, malaria, mosquitos, HMBPP, Gandalf, amoeba, Severus Snape, pellagra, biolegend  

The Talkin' Immunology podcast makes its return for the new year! We discuss peanut allergies, the new Mesentery organ, and the joy of tickling rats! Topics Introducing peanuts to children at young age may prevent allergies later in life Meet your new organ: the Mesentery Keeping the science honest on TV shows Lying may wire your brain to keep lying Rats enjoy a good tickle Teen worms are like human teens Transmissible cancer and genetic variations in Tasmanian Devils Keywords: peanuts, food allergies, podcast, BioLegend, immunology, oral tolerance, hygiene hypothesis, mesentery, lying, tickling, Tasmanian devil, cancer  

Our guest, Anita Bandrowski from UCSD and SciCrunch, talks about how to make sure your research is transparent, rigorous, and how journals are upping their standards for reagent listings.TopicsSciCrunch Resource Identification Initiative Anita Bandrowski convinces audience that grandmothers do more reproducible science than scientists BioLegend Joins the Resource Identification Initiative to Improve Research ReproducibilityBioLegend to provide $100,000 in research reagents to The Reproducibility InitiativeCiteAb Reproducibility with Andy ChalmersKeywords: journals, anita bandrowski, scicrunch, reproducibility,  

In our latest podcast, we chat with Andy Chalmers about the challenges of research reproducibility and how his website, CiteAb, is striving to better document reagent use in publications. Topics CiteAb BioLegend provides $100,000 in reagents to The Reproducibility Initiative The Reproducibility of Published Research Blog Keywords: antibodies, reproducibility, science, podcast, research, Andy Chalmers, BioLegend, journals, publications, validation, knockout, negative control  

We discuss a CRISPR TV show, the genes and diseases inherited from Neanderthals, and how mice can be sensitized to pain by smell. Topics How snakes lost their legs CRISPR TV drama by J-Lo Autism in neurofibromatosis type 1 linked to a single gene Mental health issues may originate from breeding with Neanderthals HPV-16 transferred from Neanderthals Pain can move from one mouse to another via smell You smell and mice can tell Keywords: TLR, Neanderthal, cross-breeding, crispr, jennifer lopez, smell, pain, autism, hpv, papillomavirus, snakes, sonic hedgehog, HOXD, BioLegend, podcast