Podcasts about viruses

John Leake joins Frank and J Gulinello to discuss his book Mind Viruses: America's Irrational Obsessions and the fears that keep reshaping American life. From the War on Terror and COVID to a Massachusetts bar still fighting over masks, we'll ask how a crisis becomes a moral mission—and why its rules survive after the emergency fades. Later, J stays for open lines, super chats, drug commercial side effects, and checking the score of the Yankees game. My daily Health Stack Consists of KetoBrainz Nootropics & Nattokinase 15% OFF EVERYTHING on KetoBrainz.com w/ code SEPTEMBER E-Mail me @ Frank@QuiteFrankly.tv for FREE SAMPLES! JOIN THE CULTURE CLUB! Read books. Watch films. Keep Quite Frankly independent. Become a member: https://www.quitefrankly.tv/sponsor SUPPORT QUITE FRANKLY One-Time Tip: https://www.paypal.me/QuiteFranklyLive Quite Frankly Amazon Storefront: https://amazon.com/shop/quitefranklyofficial Frank's Elevation Blend Coffee: https://www.coffeerevolution.shop/category/quite-frankly Frank's Official Merch: https://tinyurl.com/f3kbkr4s Gold & Silver: https://quitefrankly.gold SEND MAIL TO THE SHOW Send cards, letters, and small gifts to: Quite Frankly 222 Purchase Street, #105 Rye, NY 10580 TIP IN CRYPTO BTC: bc1q97w5aazjf7pjjl50n42kdmj9pqyn5zndwh3lng XRP: rnES2vQV6d2jLpavzf7y97XD4AfK1MjePu CONNECT WITH QUITE FRANKLY X/Twitter: @QuiteFranklyTV Instagram: @QuiteFranklyOfficial Discord: https://discord.gg/xPu7YEXXRY Telegram: https://t.me/quitefranklytv WATCH LIVE QuiteFrankly.tv — Powered by Foxhole: https://www.quitefrankly.tv YouTube: https://tinyurl.com/yc2cn395 Rumble: https://tinyurl.com/yeytwwyz Twitch: https://www.twitch.tv/quitefranklylive LISTEN ON DEMAND Please leave a nice rating—it helps the show! Spotify: https://tinyurl.com/59vma35y Apple Podcasts: http://apple.co/2dMURMq #MindViruses #JohnLeake #ManufacturedFear #PsychologicalWarfare #MediaManipulation #QuiteFrankly

Turnbuckle Tavern is powered by G FUEL and Official Dick Lazer. Use code TAVERN for 20% off at GFUEL.com and DickLazers.com. This week, Wrestling Tonight asks whether WWE is wrong for airing Worlds Collide opposite AEW's tribute to Benjamin Satterley, known around the world as PAC. Dynamite will celebrate PAC's life and career Wednesday night, while WWE, NXT and AAA's previously scheduled Worlds Collide begins one hour earlier on YouTube. We break down the debate over whether WWE should have moved the show out of respect, or whether the fact that Worlds Collide was already scheduled and can be watched on demand changes the conversation. We also have new details on WrestleMania 43 in Saudi Arabia. Fightful Select reports that WWE hopes to announce the official date around Crown Jewel in Riyadh on November 7 if it isn't revealed sooner. Saudi representatives have reportedly visited WWE headquarters for kickoff meetings, the dates are said to be largely settled internally, and independent promotions are waiting for the announcement before determining their own WrestleMania weekend plans. Plus, Maxwell Jacob Friedman tops the PWI 500 for the first time after a huge year across AEW and CMLL, responding with a very MJF "What took so long?" Cody Rhodes, CM Punk, Místico and Konosuke Takeshita round out the top five. In NXT, Mason Rook's first NXT Championship opportunity was pulled just hours before he was scheduled to challenge Grayson Waller after WWE announced that Rook was not medically cleared. Robert Stone later revealed that Rook will be out for the foreseeable future, leading to EK Prosper answering Waller's open challenge instead. We also catch up on the Dusty Rhodes Tag Team Classic as Chazz "Starboy" Hall & Mini Vikingo and Nathan Frazer & Axiom advance. Finally, we look ahead to CMLL's Thursday return to Arena Coliseo in Mexico City, with Titan, Euforia, Valiente, Virus and more featured across the five match card. Be sure to support the show and join our Patreon for just $2.99 a month at PATREON.COM/THETURNBUCKLETAVERN for exclusive content, and follow @turnbuckletavern across social media for all the latest updates. Until the following week, when we wine and dine with you kings and queens, stay out of the alley and away from the pork and beans. God luck and good speed.

In this episode of Living Well with MS -- where we explore topics relating to living a full and healthy life with multiple sclerosis -- we are pleased to welcome Brett Drummond and Karen Campbell. Brett is from MSTranslate and hosts the European Committee for Treatment and Research In Multiple Sclerosis (ECTRIMS) patient day and podcast. Karen is a nurse and MS researcher who lives with MS and attended the conference this year. Watch this episode on YouTube. Keep reading for the topics, timestamps, and our guest's bio. 00:00 Introduction to ECTRIMS 2025 and Speakers 02:02 Overview of ECTRIMS Conference Highlights 02:41 Brett's Insights on MS Research 09:07 Emerging Treatments and Therapies for MS 15:10 The Role of Viruses in MS 18:28 Lifestyle Modifications and Rehabilitation in MS 20:03 Biomarkers and Their Importance in MS 24:24 Engaging the MS Community in Research 28:24 Karen's Perspective as a Patient and Researcher 33:55 Q&A Session: Addressing Community Questions Watch the original presentation here Connect with Ciara on LinkedIn New to Overcoming MS? Learn why lifestyle matters in MS - begin your journey at our 'Get started' page Connect with others following Overcoming MS on the Live Well Hub Visit the Overcoming MS website Follow us on social media: Facebook Instagram YouTube Pinterest Don't miss out: Subscribe to this podcast and never miss an episode. Listen to our archive of Living Well with MS here. Make sure you sign up to our newsletter to hear our latest tips and news about living a full and happy life with MS. Support us: If you enjoy this podcast and want to help us continue creating future podcasts, please leave a donation here. Feel free to share your comments and suggestions for future guests and episode topics by emailing podcast@overcomingms.org. If you like Living Well with MS, please leave a 5-star review.

Con la llegada del otoño vuelven los resfriados, la tos, las fiebres y las visitas al pediatra, pero no todos los virus son iguales. Hoy vamos a hablar de tres de los protagonistas de esta época del año: la gripe, el COVID y el virus respiratorio sincitial y lo hacemos con José Tomás Ramos Amador, catedrático de Pediatría de la Universidad Complutense de Madrid y experto en Infectología Pediátrica.

Czabe is joined by ANDY POLLIN and GENE WANG to talk sports over a lovely steakhouse lunch!00:00 Introduction and Episode Overview01:49 Media Day and Sports Media Personalities03:48 Washington Wizards and NBA Turnaround Potential06:55 NFL Flopping and Rule Changes08:48 The Problem with Replay and Referee Decisions11:48 The Entertainment Value of the NFL14:53 Commanders' Win and Turnover Analysis19:07 NFL and League Policies on Flags and Penalties21:46 Maryland Football and Coaching Challenges25:01 Golf and Media Interactions with Scotty Scheffler28:06 The Evolution of Coaching and Game Management33:03 Clock Management and Decision-Making in the NFL36:13 The Role of Analytics and Data in Sports39:54 The Impact of Player Injuries and Load Management45:01 Baseball Playoff Formats and Their Effectiveness53:58 The Future of Sports and Analytics59:54 Athletic Evolution and Injury Rates01:04:54 Closing Remarks and Next StepsOur Sponsors:* Check out Ethos and use my code ethos.com/czabe for a great deal: https://www.ethoslife.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

We speak to SEGA Producer Ed Annunziata and dive deep on SEGA's X-Men, X-Men 2: Clone Wars and the unreleased  X-Women: Sinister's Virus!

Eine richtige Grippe ist etwas ganz anderes als eine einfache Erkältung. Jeder, der schon mal eine solche Influenza hatte, weiß das: Hohes Fieber, rasende Kopfschmerzen, trockener Husten und völlige Abgeschlagenheit - und das über Wochen. Inzwischen weiß man, dass eine Grippe auch zum Herzinfarkt, Schlaganfall oder eine tödliche Herzrhythmusstörung mit Herzversagen führen kann. Gerade bei älteren Menschen oder Risikogruppen. Eine Grippeimpfung kann - zumindest zum Teil - davor schützen. Aber die Deutschen sind impfmüde. Regional sind die Zahlen unterschiedlich: Schlusslicht ist Baden-Württemberg. Dort ließ sich zuletzt nur ein Fünftel der über 60-Jährigen impfen. Ganz vorne lag dagegen Sachsen-Anhalt mit 52 Prozent. Norddeutschland bewegt sich eher in der Mitte, so zwischen 43 und 45 Prozent, wobei Hamburg weiter hinten liegt. Wann man sich impfen lässt, will gut überlegt sein, sagt Korinna Hennig aus der ARD Gesund Reaktion. Denn der Impfschutz lässt nach einigen Monaten nach. Und die Grippesaison beginnt oft erst nach Weihnachten. Vieles spreche auch dafür, Kinder gegen Grippe impfen zu lassen. Der Infektiologe Mathias Pletz von der Universität in Jena verweist auf NDR Info darauf, dass Grippeimpfungen kaum Nebenwirkungen haben. Und auch wenn sich das Virus kontinuierlich verändert und damit eine Impfung auch nicht jedes Jahr gleich wirksam ist, rät er zur Pieks gegen die Grippe. Denn so könne der Verlauf einer Erkrankung abgemildert werden.weitere Informationen:Start der Grippesaison - wer sollte sich impfen lassen?https://www.ndr.de/audio-3505030.htmlGrippe (Influenza): Symptome, Behandlung und Impfunghttps://www.ndr.de/grippe198.htmlInfektiologe Pletz: Grippeschutzimpfung unbedingt empfehlenswerthttps://www.ndr.de/audio-3504900.htmlAlle Folgen von “NDR Info Thema” auch in ARD-Soundshttps://www.ardsounds.de/sendung/urn:ard:show:193cce6e1dd33420/Moderation: Peter Mücke Interviews: Stefan Schlag Planung: Bernd Musch-Borowska Produktion/Distribution: Mathias Stössner

For more, visit www.BishalSarkar.com or WhatsApp our team: https://wa.me/918880361526In this enlightening episode of the "I Love Public Speaking" podcast, Bishal Sarkar reveals three mental viruses that can undermine your confidence.Join Bishal Sarkar as he discusses how these negative thought patterns affect your self-assurance and overall performance.Learn effective strategies to identify and eliminate these viruses, paving the way for a more confident and empowered version of yourself.Tune in to the "I Love Public Speaking" podcast with Bishal Sarkar to discover how to cultivate super confidence by removing these detrimental influences.

Aucune entreprise n'est à l'abri d'une cyberattaque. Souvent moins équipées face à ces menaces, les entreprises artisanales doivent rester particulièrement vigilantes.Virus, ransomware, vol de données… Quels risques pour l'activité d'une entreprise artisanale et comment renforcer sa protection au quotidien ?On fait le point avec Bruno.Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

Depuis la pandémie de Covid-19, le gel hydroalcoolique est devenu pour beaucoup un réflexe presque automatique. Pourtant, face à certains microbes, il est beaucoup moins efficace qu'on pourrait le croire. C'est notamment le cas d'un virus responsable de nombreuses gastro-entérites : le norovirus.Le norovirus provoque généralement des vomissements, des diarrhées et des douleurs abdominales. Très contagieux, il circule particulièrement pendant les mois froids et peut provoquer des épidémies spectaculaires dans les écoles, les maisons de retraite, les hôpitaux ou encore les bateaux de croisière.Les recherches menées sur ce virus, notamment au laboratoire du virologue Johan Neyts à la KU Leuven, en Belgique, mettent en évidence son extraordinaire capacité de transmission. On estime qu'une quantité infime, de l'ordre de quelques dizaines de particules virales — parfois seulement 18 — peut suffire à provoquer une infection.Mais pourquoi résiste-t-il si bien au gel hydroalcoolique ?Une partie de l'explication vient de sa structure. Contrairement au coronavirus ou au virus de la grippe, le norovirus est un virus dit non enveloppé. Il ne possède pas la membrane graisseuse externe que l'alcool détruit très efficacement chez de nombreux autres virus. Il est entouré d'une coque protéique particulièrement robuste.Résultat : les solutions hydroalcooliques peuvent diminuer la quantité de norovirus présente sur les mains, mais elles ne constituent pas la méthode la plus fiable pour s'en débarrasser.Le geste le plus efficace reste beaucoup plus classique : se laver soigneusement les mains à l'eau et au savon pendant au moins une vingtaine de secondes, en frottant toutes les surfaces des mains. Ici, l'action est notamment mécanique : le savon et le rinçage permettent de décrocher les particules virales de la peau puis de les évacuer dans l'eau.Cette précaution est particulièrement importante après être allé aux toilettes, après avoir changé une couche et avant de préparer ou de consommer des aliments.Même problème avec les surfaces. Après des vomissements ou des diarrhées, un simple spray à base d'alcool peut être insuffisant. Des produits spécifiquement efficaces contre le norovirus, notamment ceux à base d'hypochlorite de sodium, c'est-à-dire d'eau de Javel utilisée selon les recommandations de dilution, sont privilégiés.Le norovirus nous rappelle donc une chose essentielle : désinfecter ses mains et les laver ne sont pas exactement la même chose. Face à ce virus particulièrement tenace, le bon vieux savon conserve un sérieux avantage. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

We're now several years, thankfully, past the COVID-19 pandemic, but as even a casual glance at daily news headlines reminds us, the challenge posed by infectious diseases is not going anywhere anytime soon. And with the arrival of fall weather and the holiday gatherings that will soon be right around the corner, it's an excellent time to check in with one of the world's pre-eminent infectious disease experts — Dr. David Wohl. Dr. Wohl is a Professor of Medicine in the Division of Infectious Diseases at UNC, and he's spent over 20 years leading research into the prevention and treatment of HIV. In 2020, he helped lead the UNC clinical and research response to COVID-19. And this past week, Dr. Wohl was kind enough to make some time to chat with NC Newsline about how North Carolinians can best protect themselves and their families from any number of dangerous infectious diseases. Click here to listen to the full interview with Dr. David Wohl , Professor of Medicine in the Division of Infectious Diseases at UNC.

Become a supporter of this podcast: https://www.spreaker.com/podcast/prepper-broadcasting-network--3295097/support.Head to https://bepreparedsolutions.co/partner/pbn, or use code PBN20 when you sign up to get 20% off their incredible preparedness tools, custom plans, and LOCAL INTELLIGENCE. STOP THE ADS! Become a PBN Supporter for just $5 a month and get exclusive podcasts just for supporters. BECOME A SUPPORTER The Prepper's Medical Handbook Build Your Medical Cache – Welcome PBN FamilyJoin the Prepper Broadcasting Network for expert insights on #Survival, #Prepping, #SelfReliance, #OffGridLiving, #Homesteading, #SelfSufficiency, #Permaculture, #OffGrid solutions, and #SHTF preparedness. With diverse hosts and shows, get practical tips to thrive independently – subscribe now!Newsletter – Welcome PBN FamilyGet Your Free Copy of 50 MUST READ BOOKS TO SURVIVE DOOMSDAY

#ElGranMusical. Daniel Simancas. Virus causados por el fenómeno de El Niño by FM Mundo 98.1

2026-09-28 - Veckans sändning nyheter med svensk synth från Fräuleine Frake, Pigmachine, LeeZeth och Analfabetism. Internationellt från Kramm, Pharaoh Overlord, B1980 och Chvrches.

The San Diego Sheriff's are alerting the public about a sexually violent predator now on the run after escaping supervision in Rancho Bernardo. San Diego County health leaders tell NBC 7 there are currently 11 human cases of West Nile Virus, the highest caseload they've seen in ten years. This weekend, the annual air show is back at Marine Corps Air Station Miramar.What You Need To Know To Start Your Saturday.

Depuis la pandémie de Covid-19, le gel hydroalcoolique est devenu pour beaucoup un réflexe presque automatique. Pourtant, face à certains microbes, il est beaucoup moins efficace qu'on pourrait le croire. C'est notamment le cas d'un virus responsable de nombreuses gastro-entérites : le norovirus.Le norovirus provoque généralement des vomissements, des diarrhées et des douleurs abdominales. Très contagieux, il circule particulièrement pendant les mois froids et peut provoquer des épidémies spectaculaires dans les écoles, les maisons de retraite, les hôpitaux ou encore les bateaux de croisière.Les recherches menées sur ce virus, notamment au laboratoire du virologue Johan Neyts à la KU Leuven, en Belgique, mettent en évidence son extraordinaire capacité de transmission. On estime qu'une quantité infime, de l'ordre de quelques dizaines de particules virales — parfois seulement 18 — peut suffire à provoquer une infection.Mais pourquoi résiste-t-il si bien au gel hydroalcoolique ?Une partie de l'explication vient de sa structure. Contrairement au coronavirus ou au virus de la grippe, le norovirus est un virus dit non enveloppé. Il ne possède pas la membrane graisseuse externe que l'alcool détruit très efficacement chez de nombreux autres virus. Il est entouré d'une coque protéique particulièrement robuste.Résultat : les solutions hydroalcooliques peuvent diminuer la quantité de norovirus présente sur les mains, mais elles ne constituent pas la méthode la plus fiable pour s'en débarrasser.Le geste le plus efficace reste beaucoup plus classique : se laver soigneusement les mains à l'eau et au savon pendant au moins une vingtaine de secondes, en frottant toutes les surfaces des mains. Ici, l'action est notamment mécanique : le savon et le rinçage permettent de décrocher les particules virales de la peau puis de les évacuer dans l'eau.Cette précaution est particulièrement importante après être allé aux toilettes, après avoir changé une couche et avant de préparer ou de consommer des aliments.Même problème avec les surfaces. Après des vomissements ou des diarrhées, un simple spray à base d'alcool peut être insuffisant. Des produits spécifiquement efficaces contre le norovirus, notamment ceux à base d'hypochlorite de sodium, c'est-à-dire d'eau de Javel utilisée selon les recommandations de dilution, sont privilégiés.Le norovirus nous rappelle donc une chose essentielle : désinfecter ses mains et les laver ne sont pas exactement la même chose. Face à ce virus particulièrement tenace, le bon vieux savon conserve un sérieux avantage. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Vírus Carinhoso é cantor, compositor e rapper baiano, um artista que transforma palavra, ritmo e vivência em música. Com uma obra atravessada pela poesia e pela força da cultura urbana, ele constrói pontes entre o rap e outras sonoridades brasileiras. Um nome de personalidade própria, que faz da música espaço de encontro, afeto e reflexão. Uma conversa necessária numa semana tão importante pro país.

What happens when John Moxley and Will osprey go "all out" On the red cross? Prob the same thing that happens to People who wanted to wear that Trick Williams "Cancelled" Merch...something straight out the mind of Zach Cregger and Vince McMahon's wildest dreams... E-Ray & The wiseman take the reigns and go off the rails this week. Listen as they break down this week in graps and prophecize on things to come to pass as only this Beige brigade can... Follow us on social media:IG: Instagram.com/letmebookpodX: x.com/letmebookpodYT: youtube.com/letmebookpod

Dr. Justin Abbatemarco and Dr. Irene Cortese discuss recent advances in the treatment of progressive multifocal leukoencephalopathy (PML), focusing on immune-based therapies like virus-specific T cells and immune checkpoint inhibitors.  Show citation:  Gonzalez CE, Fletcher A, Jenkins TL, et al. Resolution of PML after Treatment with Virus-Specific T Cells and HCT. N Engl J Med. 2026;394(20):2061-2064. doi:10.1056/NEJMc2514186 

Listen to these guys try to figure out what's real and what's the matrix.Rate Us ⭐⭐⭐⭐⭐ on Apple Podcasts!Connect With The Show: Follow Us On Instagram Follow Us On Twitter Follow Us On TikTok Visit Us On The Web  

durée : 00:21:04 - Journal de 08h00 - Le pape Léon XIV arrive à Paris, vendredi, pour une visite apostolique. Emmanuel Macron veut envoyer des moyens militaires français en Arabie saoudite pour protéger un site énergétique. Près de 120 contaminations au virus du Nil occidental recensées en France, depuis le début de l'année. - équipe : Hélène Fily Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France

In this episode, a conversation with writer and reporter Michael Dulaney, author of a new nonfiction book, Sentinels. Humans have long observed animals for advanced warnings of danger – but what can they tell us about the growing threat of contagion in the age of climate change? Diseases today reveal our close ties to animals. Viruses leap from bats to camels to humans. Cats catch the flu, and tourists pass tuberculosis to elephants. In recent years, however, something has changed. Exploitation of the environment is causing more diseases to jump species than ever before – a threat to life that rivals climate change. The science is clear: the cause of this great acceleration is us. In Sentinels, Michael Dulaney takes readers from southern China to the Andes, from the Arctic to Australia, to tell the gripping stories of the people and animals at the forefront of this enormous change. Dulaney joins ecologists tracking flying foxes through Australia's eastern forests, and frog hunters netting endangered species on Indonesian mountains. Along the way, we meet lemmings that resist global warming, coastal seals with bird flu, and genetically engineered disease-proof pigs. Combining vivid field reporting with natural history, these stories move beyond the fear of contagion to explore the beauty and resilience of life, and the human capacity to regenerate as much as to destroy. Urgent, moving, and deeply informed, Sentinels is an essential reckoning with our intimate connection to nature, but also a call to build a fairer world for all. Enjoyed what you heard? Click here to purchase the book: https://www.readings.com.au/product/9781761381409/sentinels--michael-dulaney--2026--9781761381409

Dr. Justin Abbatemarco talks with Dr. Irene Cortese about recent advances in the treatment of progressive multifocal leukoencephalopathy (PML), focusing on immune-based therapies like virus-specific T cells and immune checkpoint inhibitors.  Read the related article in The New England Journal of Medicine.  Disclosures can be found at Neurology.org.  Show transcript:  Dr. José Merino: This is José Merino, editor-in-chief of the Neurology Family of Journals. The Neurology Podcast provides practical information to neurologists and other clinicians to help them provide better care for their patients. Thanks for listening, and have a great week. Dr. Justin Abbatemarco: Hello and welcome. This is Justin Abbatemarco with the Cleveland Clinic here with Irene Cortese to discuss an update on progressive multifocal leukoencephalopathy treatment in light of a New England Journal of Medicine correspondence, Resolution of PML After Treatment with Virus-Specific T Cells and HCT. Irene directs the Experimental Immunotherapeutics Unit at NINDS. Hello and welcome. Dr. Irene Cortese: Hi, thank you for the invitation to join you today. Dr. Justin Abbatemarco: It's a pleasure to have you on and to talk about this expanding space in rare disease. And maybe if we could start off, can we just take an overview on how PML usually presents and why does it remain so difficult to treat? Dr. Irene Cortese: PML, or progressive multifocal leukoencephalopathy, is an opportunistic infection of the brain that is caused by the JC virus. And most of us carry this virus lifelong and without any symptoms, and it really only causes disease when the immune system is significantly compromised and loses the ability to keep it in check. And so when that happens, the virus can gain the ability to infect oligodendrocytes, and this can lead to the rapidly progressive demyelinating infection called PML. These lesions that develop in PML are typically located in the white matter, and they are most often multifocal. And this leads to the clinical manifestation of a combination of cortical and subcortical symptoms that evolve over weeks to months. And, unfortunately, if immune competence can't be restored quickly, then the disease is fatal within just a few months. And so that's really the core of the problem here, is that there is no effective direct antiviral treatment. And the only thing that works is restoring the immune system ability to control it, but that's often very difficult to do. When it's even possible, it's frequently just not even fast enough. And so you can see this even in situations where you'd think that we'd have an advantage, for example, in HIV-associated PML, where we do have effective antiretroviral therapy. Even there, restoring immune competence can sometimes just take too long relative to how quickly PML progresses. And so on top of all that, PML is really quite rare and is also remarkably heterogeneous because it can occur in very different patient populations from HIV to hematological malignancy to genetic immune deficiencies. And this rarity and heterogeneity really make both the diagnosis difficult and also treatment development quite difficult. Dr. Justin Abbatemarco: It's such a interesting story, and these different backgrounds really present different challenges. But at these last few years, this has been a success story in some way because we've seen so much effort and research into this rare disease space, which is encouraging. We mentioned this at the top, but there are immune checkpoint inhibitors that have at least been trialed for this T cell exhaustion to see if we can boost the immune system, and then more recently with your work around allogeneic-specific T cells to help clear the infection. What have you taken away from those updates? Dr. Irene Cortese: The biggest takeaway is that these two approaches, checkpoint inhibitors and Virus-Specific T Cells, have really transformed the way that we think about PML. So for decades, our only option was really to try to reverse the underlying immune suppressive condition and just hope that the immune system caught up in time. And now we have these two active strategies to try to speed this process up. Importantly, both these strategies have validated the same core hypothesis that even without a direct antiviral agent, we can improve PML outcomes by restoring effective antiviral immunity. And that said, each of these approaches has real limitations. So first of all, they don't work in all patients. And we have best estimates of success rates somewhere in the 50 to 60% range overall. With checkpoint inhibitors, the fundamental issue is that you're trying to unleash an immune response that has to already be there in some latent or exhausted form. For example, in patients with very advanced immune compromise where the T-cell compartment is essentially absent, there's just nothing left to invigorate, and so checkpoint blockade is really unlikely to help. And even when they do work, there is a real risk of exacerbating underlying autoimmune disease as well as the risk of leading to immune reconstitution inflammatory syndrome, or IRIS, where inflammation in the central nervous system of this immune system waking up and attacking the infection can actually lead to severe morbidity and even death in some patients. Virus-Specific T Cells have a whole different set of limitations. These are mostly practical and logistical at this point. Access is really the big one because there are only a handful of centers worldwide that can manufacture Virus-Specific T Cells. And so this just isn't something you can easily do everywhere or quickly. And also, biologically, every virus-specific T-cell product which is made from a different donor is essentially a different drug. And so it's really hard to predict how any given cell product will actually behave in a given patient. I should also mention that for both these approaches, they truly are still experimental. We don't have any controlled studies, and so most of what we're working from is really retrospective series and case reports. And we definitely have no head-to-head data. And so while we apply general principles estimating residual immune capacity or weighing the risk of exacerbating immune-mediated adverse events, we're really making individualized judgment calls rather than following an evidence-based algorithm. Dr. Justin Abbatemarco: And could you talk about those Virus-Specific T Cells? It's not something we use commonly in neurology. How do those work? And have they been used in other spaces successfully that we've been able to maybe apply some of those principles here? Dr. Irene Cortese: Yeah. So Virus-Specific T Cells were really first developed in the transplant setting, and they were essentially a way to bridge patients immediately following myeloablation. And in the period of time it took them to fully immune reconstitute a brand new immune system, it was a way to protect them from the common viral infections mostly that can develop in this time period and that led to such high morbidity and even mortality. And so the way this is done is that you basically take healthy lymphocytes from a healthy donor, and you can train them in vitro by ex vivo expansion and stimulation to basically become professional killers of the particular virus of interest so that, at the end of this expansion period, you basically have a enriched antiviral product that can be adoptively transferred to the patient recipient. And they may not last for a very long time, however, they can, especially with repeated infusions, provide the necessary immunity to bridge until definitive immune reconstitution is achieved. And so the initial experience with Virus-Specific T Cells was really against the various viruses that are so common in the post-transplant setting, like CMV, EBV, adenovirus, and also BK virus, which is a cousin, let's say, of the JC virus. And over time, the process for manufacturing Virus-Specific T Cells has become more and more streamlined. And so back as in 2015, 2017, we started to realize that perhaps these types of cell products might even be used to treat an acute infection and not just to administer in the setting of a planned transplant. And so essentially we've done exactly this, basically copied these manufacturing methods from the transplant world to make Virus-Specific T Cells against the JC virus and can then use them to treat PML. I should mention that BK virus is very similar in structure to the JC virus. And for that reason, what we learned early on when we started to apply Virus-Specific T Cells to the treatment of PML was that we could actually use Virus-Specific T Cells that were made against BK virus and successfully treat PML. More recent years, groups have been manufacturing JC virus-specific BST, but those BK Virus-Specific T Cells can still be used to treat PML. Dr. Justin Abbatemarco: That's really incredible. And it's so cool when we borrow things from these other fields to help inform rare diseases within neurology space. Maybe it's a perfect segue into the cases report in New England Journal of Medicine where you had two cases with inborn errors of immunity. You've utilized the strategy and then stem cell transplant. Walk us through those cases. What did you see? What did we learn from these that we can apply more broadly? Dr. Irene Cortese: Our paper really told the story of our experience of treating these two young men. Both of them had developed PML in the setting of an inborn error of immunity. One of them had DOCK8 deficiency, and he also had Sézary syndrome as a comorbid condition. And the second patient had a CD40 ligand deficiency. And for both these patients, we basically adopted the same strategy, which was to first try to gain control of the JC viral infection. And once that infection was actually under control, then we went ahead and proceeded to definitive treatment of their underlying genetic immune deficiency, which was transplant in their setting to correct the real root problem that they had. And what I think was perhaps most instructive in this experience is what happened after transplant in both cases. So transplant obviously involves a period of renewed immune vulnerability, and that's exactly when we feared that the PML might come back, even though we had been able to gain control, at least temporarily, using this adoptive transfer Virus-Specific T Cells. Fortunately, in these two cases, that didn't happen. And in fact, patient one actually developed IRIS shortly after engrafting with worsening neurological symptoms and also imaging that showed active inflammation, which responded well to steroids. And he's now years out with no evidence of PML or his prior malignancy, which was also treated by the transplant. The second patient's course was complicated by cryptogenic organizing pneumonia, or COP, which can happen in the post-transplant setting, and did require steroids. And this did cause a transient uptick in the JC viral copy number in the spinal fluid, but this resolved once the steroids were tapered. And this patient also is now several years out with only mild residual neurological deficits. So it's important that for both these patients, the transplant donors, in addition to undergoing collection for the transplant itself, they also underwent a collection to make extra rescue Virus-Specific T-Cell products that we had on hand just in case the PML relapsed post-transplant, which of course was not, in the end, needed. And so basically, the overall strategy for both these patients was sequential and deliberate. First to establish virus-specific immune control, and only then proceeding to the definitive but higher risk step of transplant with the safety net available in case virus reactivated during that post-transplant period. Dr. Justin Abbatemarco: The complexity of these cases, though, and the successful outcome is just incredible. And again, we don't always treat these level of patients, but most neurologists will see PML during their career. How do you think this helps inform this broader field of PML treatment in your mind? Dr. Irene Cortese: For me, these two cases really crystallized the idea of immune facilitation as a bridge rather than as a standalone endpoint. For example, in these two patients, Virus-Specific T Cells could not have led to a definitive cure because the underlying immune defect was still there, but they could buy time and control the virus long enough to get to something that could actually fix the underlying problem, which in this case was the transplant. And I'll be honest, proceeding to transplant in a patient with active or recent PML was really frightening. And clearly that is not an option or appropriate at all for the majority of patients with PML. So I guess that the broader lesson here is that Virus-Specific T Cells or potentially other immune-facilitating strategies might serve as a bridge to get us to the point where we either have a way to address that root cause of immune suppression or just buy us the time needed to recover from immune suppressive exposures and perhaps opens up the question of how we might use sequential strategies and combinations of strategies to optimize the care of these patients. Dr. Justin Abbatemarco: Really appreciate your paradigm of how you think about these cases in treatment, and yet you can have these short-term strategies to bridge patients to have an improved immune response to get this under control. Could we talk about other common examples? So we have natalizumab-induced PML cases, HIV-associated PML cases. How would you think about managing those, so outside of these inborn errors of immunity? Dr. Irene Cortese: Each PML patient is somewhat unique, and definitely the underlying condition that is driving the immune suppressed state is really critical in mapping out what we need to do. I think of HIV-associated PML or even natalizumab-related PML as being somewhat unique. Because unlike most other causes of PML, we actually do have clear and reliable ways to restore immune competence, so basically antiretroviral therapy in HIV infection or simply discontinuing the non-immune-depleting drug natalizumab in the case of natalizumab-related PML. And so this is obviously a real advantage compared to many of the other underlying conditions where there really is no good way to reverse that immune suppression at all. That said, in some patients, for example, with advanced AIDS and very low CD4 counts, immune reconstitution can still be very slow even when the HIV replication itself is well controlled. And so in a subset of patients, the PML can still really pace the recovery. And so we do sometimes need strategies to bridge that gap. And basically. we would consider the same immune restoration approaches that we've been talking about right now. There is an added layer of complexity here that's a bit more, let's say, unique to HIV-related PML or to the setting of natalizumab-related PML, which is that in both these cases, immune reconstitution is going to happen eventually. And when it does, then many of those patients do experience PML IRIS where the constituting immune response paradoxically worsens the neurological injury by attacking the infected tissue. And so this really needs to be watched for and managed typically with steroids. And certainly this risk of developing PML IRIS needs to be really considered if we are going to use strategies to boost or facilitate immune reconstitution in the setting of HIV infection or natalizumab-related PML. And we just have to be particularly mindful because there's already a very high likelihood of developing PML IRIS independently of getting that extra boost. Comparatively, in the setting of non-HIV-related PML or not in the setting of natilizumab treatment, I think that strategies like checkpoint inhibition and Virus-Specific T Cells have really been game-changing because, historically, these patients had no equivalent to antiretroviral therapy with no reliable path to reconstituting immunity. And we're really hoping that these approaches will start to bring the outcomes that we've seen, for example, among HIV-related PML and in the setting of natalizumab and PML to these other underlying conditions and achieve the same immune control and survival rates that are achieved in at least a substantial portion of these patients. Dr. Justin Abbatemarco: It's been so exciting. Again, the updates in this field when we really did... We had nothing to offer patients for so long and now to have conversations that are a little bit different. Can I ask you to peer around the corner? What does the future look like in your mind? Do you see other therapies that are potentially at play and maybe right now are there clinical trials that we could enroll patients so that we can help inform the field more broadly? Dr. Irene Cortese: Yeah. So I think that ways to facilitate and accelerate immune reconstitution have clearly been shown to be a valid strategy. And so what I expect and hope is that in the years to come, we'll learn to harness that better and learn to identify which patients are most likely to respond to particular types of strategies to facilitate immune reconstitution. It's really important, I would say, that patients participate in trials because the field really does lack controlled data and it lacks head-to-head comparisons. And so every patient enrolled in a trial or a well-structured registry is really contributing to how the next patient gets treated. And given just how rare and heterogeneous PML is, we're just not going to advance this field through isolated case reports alone. And so we really do need patients and their physicians to be willing to participate in structured and collaborative research. The Holy Grail is, of course, a direct antiviral agent that would really broaden our ability to treat patients and potentially also continue to treat whatever that underlying condition was that led them to the risk of PML in the first place, so, for example, patients receiving treatment for cancer or patients having an autoimmune disease that requires immune suppression. And so I am hopeful that eventually the direct antiviral will be identified. And along that line, what I can mention is there are certainly clinical trials that are ongoing. At NIH, we have an active natural history study from where we can funnel patients into various experimental treatment strategies, including Virus-Specific T Cells or checkpoint inhibitors. Or right now, we actually do have an ongoing trial of intravenous brincidofovir as a possible direct antiviral strategy. What I hope for the future is that we will find ways to really collaborate and to form national as well as international consortia so that we can accelerate the development of these treatments. Dr. Justin Abbatemarco: We have things we can do now, and then we can help inform care for our future patients as well. So these are great messages, and I can't thank you enough for coming on. Again, most of these developments have been under your guidance, and we appreciate your leadership in this space and helping to give us this insight into this really rare disease. For folks, they can check out the article. It's in the New England Journal of Medicine, Resolution of TML After Treatment with Virus-Specific T Cells and HCT. Irene, thank you for coming on. Dr. Irene Cortese: Thank you so much. Dr. Stacey Clardy: This is Stacey Clardy, your podcast editor. If you've enjoyed the podcast, please take a few moments to subscribe, rate, and review the Neurology Podcast through Apple Podcasts, Google Podcasts, Spotify, or wherever you listen. And remember, you can always head to neurology.orgpodcast for our full list of past episodes, or you can also search by keyword on your podcast app for any neurology-specific topics.

As many of our listeners know from news reports, emergency departments have been under enormous strain in recent years trying to manage overcrowding, the opioid addiction crisis, the consequences of an under-resourced mental health system, and rising rates of violence against staff, among many other challenges. But our guest today guest thinks there's something else that should top that list. "I think hands down the most important issue is the reimbursement model," says Dr. Ryan Stanton, president-elect of the American College of Emergency Physicians. Dr. Stanton's uniquely-informed view is built on his work leading a physician-owned group staffing two Kentucky emergency departments, serving as EMS medical director for Lexington-Fayette County, and overseeing on-track medical response crews for auto racing series such as NASCAR. In this candid conversation with Raise the Line from Elsevier host Lindsey Smith, Dr. Stanton traces how underpayment from insurers is squeezing physicians and warping the incentives of emergency care, and why he believes the profession's ability to advocate collectively, not individually, is what will move the needle. This informative episode also explores: Why he thinks physician autonomy is the antidote to burnout; His approach to communicating medical information as a TV commentator; What it's like providing care at a NASCAR race when the “car is still smoking.” Mentioned in this episode: American College of Emergency Physicians If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

With so much sickness on this planet, can we give it to a tree? A bigger story rests in the idea of a tree giving you the virus first. What?Become a supporter of this podcast: https://www.spreaker.com/podcast/arroe-collins-like-it-s-live--4113802/support.

Tenéis la ópera prima de Destry Allyn Spielberg (sep, hija de Kate Capshaw y tito Spielberg) en #PrimeVideo. Se llama, NO ALIMENTES A LOS ̶N̶e̶p̶o̶ NIÑOS. Distopia. Virus que convierte a los adultos en caníbales. Grupo de jóvenes odiosos de protagonistas. Pinta bien, ¿VERDAD...? ¡Escuchad y opinad, Amig@s! También nos podéis encontrar aquí: Spotify: https://open.spotify.com/show/52i1iqZ56ACal18GPkCxiW Apple Podcasts: https://podcasts.apple.com/es/podcast/los-tres-amigos/id1198252523 Youtube: https://www.youtube.com/channel/UC3zK2XsnpHDGRujSTWHpL8Q Amazon Music: https://music.amazon.com/podcasts/e0b56d4f-4537-47e0-a252-9dfe56b5a490/los-tres-amigos Grupo de Telegram: https://t.me/LosTresAmigos https://www.facebook.com/LosTresAmigosPodcast Instagram: lostresamigospodcast Bluesky: @los3amigospodcast.bsky.social X / Twitter: @tresamigospod Threads: lostresamigospodcast Letterbox: https://letterboxd.com/LosTresAmigos/ #PleaseDontFeedTheChildren #NepoBaby #Terror #Survival #Pandemia #Distopia

Cold and flu season hits differently when one sick person somehow turns into an entire household going down one after another.Want to prevent that?This week, we're talking about how illnesses actually spread through your home and why your strategy should change depending on what you're dealing with. Respiratory viruses call for a very different game plan than the dreaded stomach bug, and understanding that difference could help you interrupt the seemingly endless cycle of sickness.We're breaking down practical strategies you can actually use, including ventilation, handwashing, disinfecting, HEPA air purifiers, humidifiers, saline sprays, hand sanitizer, UV sanitizing gadgets, and more. We also talk about what to look for before spending money on an air purifier, why humidity matters, and the simple things we prioritize when someone becomes “patient zero.”Plus: why classrooms really ARE germ factories, why Kelsea gives sick family members their own bathroom, why Rachael has strong feelings about loud sneezers, and the cold-and-flu products we think are actually worth your money.Because getting sick may sometimes be inevitable, but the entire family getting knocked down one after another doesn't have to be.(00:00:50) Rachael vs. Loud Sneezers: The Debate Nobody Asked For(00:03:50) Cold & Flu Season Practical Dos and Don'ts(00:08:00) Breaking the Chain BEFORE Your Immune System Has to Fight(00:14:12) Respiratory Virus vs. Stomach Bug: Why the Difference Matters(00:18:40) Hand Sanitizer Is Having a Moment(00:23:21) Stomach Bug? Why Handwashing Becomes King(00:30:14) Are Air Purifiers Actually Worth the Money?(00:37:00) Humidifiers: Helpful Tool or Germ Factory?(00:43:41) The Patient Zero Plan for Respiratory Illness(00:48:30) Germ Season Products: Buy It or Leave It?(00:55:40) Disinfecting Wipes & The Mistake People MakeWant to leave the TTSL Podcast a voicemail? We love your questions and adore hearing from you. https://www.speakpipe.com/TheThickThighsSaveLivesPodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The CVG Nation app, for ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠iPhone⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The CVG Nation app, for Android⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fitness FB Group⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Thick Thighs Save Lives Workout Programs⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Constantly Varied Gear's ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Workout Leggings⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Disclaimer: The information shared in this podcast is for educational and informational purposes only and is not intended as medical advice. The views expressed are those of the hosts and guests and should not be used as a substitute for professional medical diagnosis, treatment, or advice. Always consult your physician or qualified healthcare provider before making changes to your diet, exercise routine, medications, supplements, or healthcare plan.

How the incoming El Niño could bring different sea creatures to SoCal waters. L.A County is seeing a record number of West Nile virus infections in about a decade. We'll hear from fans checking out the debut of the Lucas Museum of Narrative Art. Support The L.A. Report by donating at LAist.com/join and by visiting https://laist.comSupport the show: https://laist.com

Dr. Christine Johnston, Professor at the University of Washington and expert on herpes simplex virus (HSV), takes us through different clinical scenarios on the diagnosis and management of HSV with National STD Curriculum Podcast Editor Dr. Meena Ramchandani.This podcast is dedicated to an STD [sexually transmitted disease] review for health care professionals who are interested in remaining up-to-date on the diagnosis, management, and prevention of STDs and STIs. Editor and host Dr. Meena Ramchandani is an Assistant Professor of Medicine at the University of Washington (UW), Program Director of the UW Infectious Diseases Fellowship Program, and Associate Editor of the National STD Curriculum.

As citizens of Metaldom, we love our concerts and gigs. But try as we might, we can't see all the shows we want to check out. So we all have that "Bucket List" of artists which we just never got to. So this week we cry in our beers together discussing these elusive shows. Hopefully we'll get to them someday. In our "News, Views and Tunes", we discuss the faux holiday National Day Of Rock n Roll. Musically, we crank some Anvil, L7, Belphagor, Toxic Holocaust, Warlord, Savage Grace, Virus, Lawnmower Deth and we introduce New Jersey's Midnight Hellion in our "Indie Spotlight". Horns Up!!

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Listen to all my reddit storytime episodes in the background in this easy playlist: https://www.youtube.com/playlist?list=PL_wX8l9EBnOM303JyilY8TTSrLz2e2kRGThis is the Redditor podcast! Here you will find all of Redditor's best Reddit stories from his YouTube channel. Hosted on Acast. See acast.com/privacy for more information.

For nearly 2,000 years, Christians have read about war, famine, pestilence, mass death, and a system powerful enough to control who can buy and sell.But one question has always remained…HOW?Now, the very people building the world's most powerful AI systems are warning us about where this technology could be headed. Researchers are quitting. AI experts are warning about existential risks. And now, AI is crossing into biology.This week on The Zach Drew Show, we examine the warnings coming from inside the AI industry and ask a chilling question:Are we finally building the world Scripture warned us about?The Bible hasn't changed.But the world has.And suddenly, things previous generations could only imagine through faith don't seem quite so impossible anymore.The pieces are moving. Are you paying attention?#ArtificialIntelligence #AI #BibleProphecy #EndTimes #ZachDrewShowFollow the Zach Drew show at ZachDrewShow.comPlease consider partnering with us! Visit www.zachdrewshow.com/donate/You can also write to us atIGBYPO box 797Decatur IL 62525

// artists @frannabik http://instagram.com/frannabik/ @metanoiaslo http://instagram.com/metanoiaslo @kryptomedic2000 http://facebook.com/kryptomedic // label facebook.com/zomboss.eatbrain instagram.com/zomboss_eatbrain ZOMBOSS004 sees FRANNABIK step in with Virus, joined by METANOIA and KRYPTOMEDIC. Dark, infectious and built to spread, the release brings a new strain into the ZOMBOSS world and pushes the outbreak even further. The virus is already inside.

// artists @frannabik http://instagram.com/frannabik/ @metanoiaslo http://instagram.com/metanoiaslo @kryptomedic2000 http://facebook.com/kryptomedic // label facebook.com/zomboss.eatbrain instagram.com/zomboss_eatbrain ZOMBOSS004 sees FRANNABIK step in with Virus, joined by METANOIA and KRYPTOMEDIC. Dark, infectious and built to spread, the release brings a new strain into the ZOMBOSS world and pushes the outbreak even further. The virus is already inside.

// artists @frannabik http://instagram.com/frannabik/ @metanoiaslo http://instagram.com/metanoiaslo @kryptomedic2000 http://facebook.com/kryptomedic // label facebook.com/zomboss.eatbrain instagram.com/zomboss_eatbrain ZOMBOSS004 sees FRANNABIK step in with Virus, joined by METANOIA and KRYPTOMEDIC. Dark, infectious and built to spread, the release brings a new strain into the ZOMBOSS world and pushes the outbreak even further. The virus is already inside.

Limiting the side effects of cancer treatments has been an animating force in the field of oncology for many years, and there's been progress to report on that front, but what if you could target cancer tumors without using radiation or chemotherapy and instead generate heat from inside the tumor to kill cells? That's the quest of our guest today, Dr. Hadiyah-Nicole Green, whose promising research using lasers and nanoparticles to eliminate tumors received Breakthrough Device Designation from the FDA earlier this year. “The laser beam that we're using is low power like a laser pointer, and without activation by the laser, the nanoparticles are harmless. Both are targeted just at the site of the tumor so because we don't use systemic delivery, we avoid all of the systemic side effects,” she explains.Dr. Green is also the founder and president of the Ora Lee Smith Cancer Research Foundation, named for an aunt who raised her and who died of cancer without pursuing curative treatment because of her fear of the side effects. Shortly after, her aunt's husband also died of cancer, opting for treatments that took a heavy toll on his body. “At 22 years old, I saw the horrors of cancer and the horrors of cancer treatment and just felt in my heart that there has to be something better than this,” she tells host Michael Carrese.On this fascinating episode of Raise the Line from Elsevier, we'll explore the science behind Dr. Green's approach, the challenges of raising the millions of dollars needed for human clinical trials, and rethinking the current funding landscape for cancer treatments.Mentioned in this episode:Ora Lee Smith Cancer Research Foundation If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

You have viruses sleeping inside you right now. More than 90% of adults do, and COVID can wake them up. A new study followed 1,154 people for a year. Nearly half of them had one wake back up, and one virus family kept showing up in the people who stayed sick. Epstein-Barr, cytomegalovirus, HHV6. Most of us picked them up in childhood, and most of the time they just sit there quietly. The new study in Nature tracked what happened when COVID woke them up, across 20 US hospitals. Evan H. Hirsch, MD breaks down why the trigger was inflammation and not a weakened immune system. He gets into why the family with the strongest link to Long COVID is one you have probably never heard of, and why prescription antivirals run into a wall with viruses that go back into hiding. And he shares how a client who was spending more time on the couch than with his kids got back to hiking once all of the Toxic 5 were addressed. In this episode, you'll learn: Why nearly half of the people in the study had a dormant virus reactivate during their COVID infection, and which two virus families it happened in What anelloviruses are, why most people have never heard of them, and why they had the strongest link to Long COVID in this study Why inflammation, not a weakened immune system, is what appears to wake these viruses back up, and why that applies even if you were never hospitalized The three reasons prescription antivirals run into a wall with latent viruses, and what the SHIELD trial at Mount Sinai is stacking because of it Why a study panel that does not look for Lyme, bacteria, yeast or parasites does not mean they are not there What the Toxic 5 are, and how a client got his energy back and the brain fog lifted once all five root causes were addressed Discover your fatigue score and the root causes keeping you stuck: https://myfatiguescore.com Free Fatigue Masterclass: https://fixyourfatigue.com See real results: https://energymdmethod.com/results Chapters: 00:00 - Introduction 00:34 - What the New Study Found 01:45 - The Virus Family You've Never Heard Of 02:52 - Why Dormant Viruses Wake Up 03:42 - The Strongest Link to Long COVID 04:46 - Why Antivirals Fall Short 07:35 - Addressing All of the Toxic 5 09:06 - Case Study: A Client's Recovery Subscribe to the EnergyMD Podcast for weekly conversations with leading experts on resolving ME/CFS and Long COVID by addressing the real root causes. . For more information about Evan and his program, Click Here.  Prefer to watch on Youtube? Click Here.  Please note that any information in this episode is for educational purposes only and does not constitute medical advice.

On the September 16th edition: Atlanta promises rules on Flock cameras; One Georgian has died of West Nile Virus; And get-out-the-vote efforts are underway ahead of the November midterms.

On today's show, we turn our attention to the DR Congo where the Ebola virus has spread to a 7th district.  The new numbers demonstrate 7200 cases, almost 4000 dead.  Meanwhile the war rages on.  Cat Brooks talks with Maurice Carney to debunk how the billionaire class and multinational corporations have been extracting massive wealth from Africa and undermining public health institutions and worsening the Ebola crisis in the Democratic Republic of the Congo (DRC). Maurice Carney is co-founder and Executive Director of the Friends of the Congo.   Image: CDC on Unsplash   —- Subscribe to our podcast: https://plinkhq.com/i/1637968343?to=page Get in touch: lawanddisorder@kpfa.org Follow us on socials @LawAndDis: https://twitter.com/LawAndDis; https://www.instagram.com/lawanddis/ The post The Ebola Virus Spreading in The DR Congo w/ Maurice Carney appeared first on KPFA.

Southwest Michigan's Morning News podcast is prepared and delivered by the WSJM Newsroom. For these stories and more, visit https://www.wsjm.com and follow us for updates on Facebook. See omnystudio.com/listener for privacy information.

Cancioneros regresa con nuevos episodios después de su receso de verano, y lo hace con la estrella del rock argentino, productora y performer Marilina Bertoldi. Marilina apareció por primera vez en KEXP con una sesión Live on KEXP at Home en 2020. En marzo de este año, se sentó a conversar con Albina Cabrera durante SXSW, justo después del showcase Cancioneros Live!, para hablar sobre su más reciente álbum, Para quién trabajás Vol. 1, y compartir su soundtrack personal, que incluye íconos e influencias queer como Madonna, RuPaul, y las leyendas argentinas Virus & Celeste Carballo. Cancionero curado por Marilina Bertoldi “Deeper and Deeper” — Madonna “Call Me Mother” — RuPaul “Me vuelvo cada día más loca” — Marilina Bertoldi & Juliana Gattas “Luna de miel en la mano” / “Amor descartable” — Virus “Para quién trabajás” — Marilina Bertoldi Escucha el episodio completo en audio donde sea que escuches tus podcasts, o mira el video en los canales de YouTube de KEXP y KEXP Podcasts, con subtítulos en inglés y español. Créditos Host & Producer: Albina CabreraAudio & Video Editing: Albina CabreraLatin American Content Producer & Video Editor: José PabónAudio Mastering: Jackson LongEditorial Supervision: Dusty HenryOriginal Podcast Music: Roberto Carlos Lange (Helado Negro) KEXP es una radio apoyada por sus oyentes. Apoya nuestro trabajo y ayuda a que podamos seguir produciendo historias como esta haciendo una donación en kexp.org/el-sonido. Una producción original de KEXP. Cancioneros returns with new episodes after its summer break. We kick things off with Argentine rock star, producer, and performer Marilina Bertoldi. Marilina first appeared on KEXP with a Live on KEXP at Home session in 2020. Earlier this year, she sat down with Albina Cabrera at SXSW, just after the Cancioneros Live! showcase, to talk about her latest album, Para quién trabajás Vol. 1. She shares her personal Cancionero, featuring queer icons and influences including Madonna, RuPaul, and Argentine legends Virus & Celeste Carballo. Songbook curated by Marilina Bertoldi “Deeper and Deeper” — Madonna “Call Me Mother” — RuPaul “Me vuelvo cada día más loca” — Marilina Bertoldi & Juliana Gattas “Luna de miel en la mano” / “Amor descartable” — Virus “Para quién trabajás” — Marilina Bertoldi Listen to the full episode wherever you get your podcasts, or watch the video on the KEXP and KEXP Podcasts YouTube channels, with English and Spanish subtitles. Credits Host & Producer: Albina CabreraAudio & Video Editing: Albina CabreraLatin American Content Producer & Video Editor: José PabónAudio Mastering: Jackson LongEditorial Supervision: Dusty HenryOriginal Podcast Music: Roberto Carlos Lange (Helado Negro) KEXP is listener-powered radio. Support our work and help us continue producing stories like this one by donating at kexp.org/el-sonido. An original KEXP production.Support the show: http://kexp.org/elsonidoSee omnystudio.com/listener for privacy information.

Program notes:0:33 Vaccines for RSV, flu, and Covid1:35 Studies available right now2:33 Reduction of hospital encounters for infants3:33 Maternal vaccination for RSV4:34 Gene silencing therapy for cardiomyopathy5:35 Decreased primary outcome about 20%6:35 Should we be screening?7:06 A new protein to pinpoint preeclampsia8:05 Low levels in first trimester9:08 Anchors embryo to uterus10:05 A new therapy for COPD exacerbations11:05 Phase three trial of monoclonal12:34 End

Send Zorba a message!On our 50th episode: Zorba looks at new research showing 1 in 4 NFL players have CTE, a progressive, degenerative brain disease linked to repetitive head trauma. He also talks about how this plays into youth sports. The American Heart Association calls out Zorba for something he said on the podcast. We hear a Mom Joke and Zorba talks about his recent time in Nepal, and how folks can help with the relief efforts following the recent disasters in the area.Link to support Nepal disaster reliefSupport the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!

Adam Waickman discusses the unusual reason he got into studying immunology just in humans, his important studies on Dengue virus vaccine antibodies, and the problematic phenomenon of antibody dependent enhancement. Host: Cindy Leifer Guest: Adam Waickman Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Waickman Lab Website Dengue virus human infection model (Sci Trans Med, 2022) mRNA vectored antibody against Dengue (Antiviral Res, 2025) B cell receptor enhancement of Dengue (PLoS Path, 2024) Dengue infection macrophage transcriptional profiles (J Virol, 2025) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Dr. Jared Rutter, PhD, Professor of Biochemistry at the University of Utah and Howard Hughes Medical Institute Investigator, is a leading expert on mitochondria and metabolism. He explains how mitochondria produce the energy for your cells to work but also how they regulate cell growth and replication and thereby contribute to health and disease. We also discuss how mitochondria are linked to aging, cancer, and other diseases. Our conversation explores your metabolism as the composite of trillions of individual cells and points to new ways to improve health, avoid, and treat diseases. Show notes: https://go.hubermanlab.com/297-jared-rutter Pre-order Protocols: https://protocolsbook.com Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman BetterHelp: https://betterhelp.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Jared Rutter (00:02:29) Metabolism, Cells; Aging (00:08:36) Mitochondria, Origin & Cell Complexity (00:13:07) Sponsors: Joovv & BetterHelp (00:15:16) Mitochondria Genome, Inheritance (00:18:18) Mitochondria & Spatial Distribution; Cell-Specific Metabolism (00:25:59) Nutrient Energy, Hormones, Fat Cells (00:31:13) Glucose, ATP Conversion, Pyruvate (00:36:41) Cell Choice: Energy or Growth, Cancer; Virus (00:46:02) Sponsors: AG1 & Eight Sleep (00:48:36) Microbiome, Role of Humans (00:51:44) Molecule Discovery Process, MPC1, MPC2 (00:59:42) Cell Resource Sensing, Fasting, Glucagon, Fat Cells; Neurons, Heart (01:07:03) Cell Resource Allocation, MPC, Heart Failure; Disease (01:11:46) Sponsor: Function (01:13:24) Cell Size vs Fuel Balance, Cell Identity & Disease (01:20:43) MPC Discovery, Genetics, Model Systems (01:24:29) Lactate, Oxygen, Exercise; Energy Prioritization Hierarchy (01:31:32) Cancer, Mutations, Metabolism Changes & Warburg Effect (01:36:18) Cancer Challenges & Therapies (01:43:00) Therapy Combinations, Unique Cancer Mutations & Metabolism (01:48:31) Technology to Visualize Metabolism; Disease, Metabolism & Scents (01:56:34) Excess Energy & Mitochondria, Reactive Oxygen Species (02:01:12) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Book a free consultation call with Robert Sikes for a keto or low-carb plateau: https://www.ketobodybuilding.com/callThe blocked-artery theory of heart attacks gets put under a microscope. In Episode 915 of Savage Perspective Podcast, Robert Sikes and Tom Cowan ask whether coronary plaque is the true cause of heart attacks. Cowan shares his case for small-vessel damage, lost heart energy, acid buildup, and plaque as repair. They cover coronary calcium scores, stents, statins, fat metabolism, keto, structured water, sunlight, and movement. The talk then turns to Cowan's disputed views on viruses, contagion, immunity, cancer, genetics, and vaccines. It closes with a practical challenge: test claims, track your body's response, eat real food, move, get outside, build relationships, and own your health.For more info visit: https://drtomcowan.com/Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQChapters:0:00 - What Really Causes Heart Attacks?0:42 - How to Falsify a Scientific Claim2:10 - The Blocked-Artery Theory of Heart Attacks5:18 - The 95% Blockage Paradox and Autopsy Findings8:08 - Stents, Bypasses, and the Blockage Theory10:08 - An Energy-and-Acid Theory of Heart Attacks13:23 - Diabetes, Small Vessels, and Fat Metabolism15:13 - A Forgotten Seed Extract for Heart Disease17:02 - Stroke, Keto, and the Plaque Debate19:02 - CAC Scans and the Protective Plaque Theory21:48 - The Fourth Phase of Water24:09 - What Moves Blood Through Capillaries?28:39 - Does Drinking Charged Water Help?30:36 - Viruses, Measles, and the Limits of Diagnosis32:24 - How Virology Identifies a Virus34:26 - Polio Experiments and Viral Culture39:14 - Contagion or Shared Exposure?41:55 - The 1918 Spanish Flu Prison Study45:25 - Do Bacteria and Parasites Cause Disease?49:32 - Fear, Vaccines, and Personal Agency51:02 - Questioning the Immune System and Antibody Model54:53 - A Different Theory of Cancer and Tumors56:29 - Four Proposed Causes of Sickness1:01:19 - Question Everything and Test It Yourself1:02:21 - Taking Back Personal Agency1:06:04 - Genetics, DNA, and the Double Helix1:09:57 - Control, Faith, and Two Origin Stories1:12:49 - Purpose, Homesteading, and Animals1:15:00 - Websites, Clinic, and Closing

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