Several genera of rodents
POPULARITY
Categories
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3495: Julien Saunders reflects on how perceptions of wealth are often illusions shaped by appearances, social comparison, and hidden financial struggles. Through personal stories about moving from Brooklyn to Atlanta and experiencing poverty firsthand, he reveals how “being rich” is often relative and misunderstood. His perspective encourages listeners to question superficial benchmarks of success and pursue financial progress grounded in reality rather than comparison. Read along with the original article(s) here: https://richandregular.com/the-road-from-rats-to-riches/ Quotes to ponder: "More often than not, you're comparing yourself to a pipe dream and ignoring that others are glamorizing you the way you're drooling over others." “The trouble with the rat race is that even if you win, you're still a rat”. "Comparing your lifestyle to others is dangerous." Learn more about your ad choices. Visit megaphone.fm/adchoices
What can happy rats teach us about human joy? Behavioral neuroscientist Kelly Lambert describes how her team trained rats to drive tiny cars to earn treats — and noticed something surprising about how effort and anticipation affect the brain. The experiment opens new questions about how reward, agency and "behaviorceuticals" might help build resilience and support mental health.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.
We play our favorite hump day game "Rats Off A Ship" where Marcos gives us a topic and we choose if we like it (Rats not off a ship) ior don't like ( Rats Off A Ship)
Tangent hive, THIS is your episode. We've got a rare in-person recording on our hands and hoooo boy do these two cover a RANGE of topics. Rats. Bloomin onions. The Purge. Davidoff Cool Water. Auditions. Tongue twisters. The New Girl episode too, of course. But it wouldn't be The Mess Around without a healthy dose of metaphorical roaming around, ya know?Follow @TheMessAroundPod on Instagram, TikTok and YouTube.Rate The Mess Around on Apple Podcasts and Spotify!This is a Headgum podcast. Follow Headgum on Twitter, Instagram, and Tiktok.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Just another song about a guy named Bob who inadvertantly sets off alarms in local businesses. No one knows why.
In this episode of Stephanie Miller's Happy Hour Podcast, Stephanie navigates the chaotic landscape of international politics, including the looming threat of war and the absurdities of the current administration. With humor and insight, she touches on everything from the absurdity of political feuds among right-wing figures to the heartbreaking loss of friends in the industry. Joined by Pastor John Pavlovitz and Rude Pundit, they delve into the moral implications of the U.S. military's actions and the pressing need for accountability in leadership. They also tackle the challenges of navigating friendships across political divides and the importance of standing firm against authoritarianism. Tune in for a blend of levity and serious discussion as they explore the current state of affairs and what it means for the future.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
See omnystudio.com/listener for privacy information.
No Jordana on this Thursday so we turn to our relationship and life expert - Chad Hartman who is here to help the masses and lead you in the right direction!
On this hump day version of the Tobin & Leroy show - All Praise to Bam Adebayo after he scored 83 points the 2nd most by a player in NBA history in the Heat's 150-129 win over the Wizards. - Bam received love and hate from peers in the NBA - Florida Panthers beat the Detroit Red Wings 4-3 in an exciting game - Miami Dolphins restructured the contract of OT Austin Jackson to get under the salary cap - Team USA lose to Italy and could be out of the WBC - Wednesday Mix Bag - Our favorite hump day game "Rats off Ship"
On Today's Rats Off A Ship: - Stephen A Smith and Victor Wembyana on Bam's 83 point performance -Team USA losing t Italy in the WBC - Ronda Rousey ripping the UFC
Natalie and David shirk their responsibilities by drinking beer and watching TV with Chandler in "The One with Phoebe's Rats" and shirk their responsibilities by drinking beer and watching TV with Ted in "The Rehearsal Dinner."See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In episode 2019, Jack and Miles are joined by comedian and host of Intercepts, David Huntsberger, to discuss… Trump Administration Blames Rising Oil Prices On Bad Vibes, Predator / Conan / Commando, Ballet And Opera Lovers Sure Are Pissed At Timothée Chalamet, Pentagon Has Been Havana Syndrome-ing Rats? And more! As oil prices spike, G7 opts not to dip into emergency reserves for now Trump's energy chief blames oil price spike on market fear 'Night turned into day': Iranians tell of strikes on oil depots As Iran chokes Strait of Hormuz, U.S. vows $20B for maritime reinsurance Scoop: U.S. dismayed by Israel's Iran fuel strikes, sources say US military tests on secret weapon bought from Russian criminal network reveal Havana Syndrome-like symptoms: report Unsurprisingly, tonight's 60 Minutes episode covering Havana Syndrome didn't offer a smoking gun because it was a sales pitch for a book coming out in September. The authors? Two 60 Minutes producers. All we've got to say is... use promo code TIMOTHEE to save 14% off select seats for Carmen, through this weekend only. Timmy, you're welcome to use it too
Israel claims a strike on Iran's cyber warfare headquarters. The Trump administration releases a new national cyber strategy. DHS shakes up its IT and cybersecurity leadership. Velvet Tempest uses ClickFix to drop loaders and RATs. Researchers uncover a Linux cryptocurrency clipboard hijacker. The DOJ brings a Ghanaian romance scammer to justice. Online advertising enables government tracking. Monday business breakdown. Our guest is Jon France, CISO from ISC2, sharing some insights and findings from their 2025 ISC2 Cybersecurity Workforce Study. An Apple II app gets audited by AI. Remember to leave us a 5-star rating and review in your favorite podcast app. Miss an episode? Sign-up for our daily intelligence roundup, Daily Briefing, and you'll never miss a beat. And be sure to follow CyberWire Daily on LinkedIn. CyberWire Guest Joining us today is Jon France, CISO from ISC2, sharing some insights and findings from their 2025 ISC2 Cybersecurity Workforce Study. For further detail, you can also check out ISC2's just released Women in Cybersecurity report. Selected Reading Iranian cyber warfare HQ allegedly hit by Israel | brief (SC Media) Iran internet blackout reaches 6th day as rights groups call for end to digital shutdown (The Record) The long-awaited Trump cyber strategy has arrived (CyberScoop) DHS CISO, deputy CISO exit amid reported IT leadership overhaul (FedScoop) Termite ransomware breaches linked to ClickFix CastleRAT attacks (Bleeping Computer) ClipXDaemon: Autonomous X11 Clipboard Hijacker Delivered Via Bincrypter-Based Loader (Cyble) Ghanaian Pleads Guilty to Role in $100m Romance Scam (Infosecurity Magazine) The Government Uses Targeted Advertising to Track Your Location. Here's What We Need to Do. (Electronic Frontier Foundation) Zurich Insurance Group intends to acquire UK cyber insurer Beazley for approximately $11 billion. (N2K Pro Business Briefing) Microsoft Azure CTO says Claude found vulns in Apple II code (The Register) Share your feedback. What do you think about CyberWire Daily? Please take a few minutes to share your thoughts with us by completing our brief listener survey. Thank you for helping us continue to improve our show. Want to hear your company in the show? N2K CyberWire helps you reach the industry's most influential leaders and operators, while building visibility, authority, and connectivity across the cybersecurity community. Learn more at sponsor.thecyberwire.com. The CyberWire is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices
In Episode 291 we look back at some hidden gems from 2020-2024. We each name at least one game that doesn't get discussed much anymore from each of these years and talk about why they deserve more attention.Timestamps:00:00 Introduction00:49 Top 5 Overlooked Board Games (2020-2024)05:00 2020 - Whistle Mountain (Rajas of the Ganges: The Dice Charmers, The Castles of Tuscany, Star Wars Unlock, Mariposas)10:22 2020 - Godspeed11:23 2020 - New York Zoo15:20 2021 - Viking See-Saw (Boon Lake, Mille Fiori, Messina 1347)21:26 2021 - Dune: A Game of Conquest and Diplomacy25:42 2021 - The Emerald Flame27:33 2021 - That Time You Killed Me33:18 2022 - Vagrantsong (Sea Salt & Paper, Woodcraft, Creature Comforts, Paperback Adventures) 39:49 2022 - Mosaic: A Story of Civilization41:47 2022 - Age of Galaxy42:37 2022 - Aeon Trespass Odyssey44:29 2022 - Three Sisters48:45 2023 - Imperial Miners (Pirates of Maracaibo, Rats of Wistar, Surfasaurus Max)53:56 2023 - Fractal, Robot Quest Arena56:35 2023 - Europa Universalis: The Price of Power59:28 2023 - Sea Dragons1:03:33 2024 - Lone Wolves (Let's Go To Japan, Fromage, Rebirth, Windmill Valley, Flip 7, Captain Flip, Invincible: The Hero Building Game, Stamp Swap, Spring Cleaning)1:08:50 2024 - Frozen Frontier, Biohack1:10:08 2024 - Reforest, LoootIf you enjoy the show, please consider supporting us at https://www.patreon.com/boardgamehottakesFollow us on BlueSky: https://bsky.app/profile/boardgamehottakes.bsky.socialJoin our Board Game Arena Community: https://boardgamearena.com/group?id=11417205Join our Discord server at: https://discord.gg/vMtAYQWURd
In today's episode, we feature the first of many videopodcasts to come! Our usual host, Danny Barrett (and his support dog), unveils the secrets to nailing the first minutes of a campaign and of every session.You'll also learn how to build modular encounters that can adapt to any scenario your players might throw at you.Thanks for listening to today's show. If you like our stuff and want to support us, here are some sponsor links and links to our other stuff:Worldsmith: http://session0studios.com/worldsmithRoll and Play Press: http://session0studios.com/rollandplayPhantasm Studios: https://session0studios.com/fantasmsMonument Studios: session0studios.com/monumentstudiosDiscord: http://session0studios.com/discordPatreon: https://session0studios.com/patreonDungeon Master Level Up Guide: https://session0studios.com/newsletter
Little Boy Rats Out Mom on Live TV - Video
Send a textMore than 90 percent of drugs that pass animal tests fail in humans. So why do we still rely on animal research? Our guests unpack the scientific and ethical flaws of animal testing and highlight the advanced, non-animal methods that are proving to be faster, safer, and more effective. We're talking about better science for both people and animals. Learn more: https://www.humaneworld.org/en/issue/animal-testing-researchLove and compassion for animals can bring everyone together. ‘Humane Voices' is the official podcast of Humane World for Animals. We'll explore the issues facing animals, interview worldwide animal experts, and discuss what you can do to get involved and help. If you care about the welfare of animals, or have a special pet or two in your life, this is the podcast for you.
Each week we aim to bring together the biggest events in Vtubing and talk about what's been going on. Stop by, hang out, and let's catch up with us! Quick reminder that we record on Tuesdays so some large stories from the week may not appear. Buy Merch Here! https://otamerch.shop/ Join this discord : https://discord.gg/M7tVYWTSFR Follow here for updates: https://twitter.com/SuperChatsPod Shorts over here: https://www.tiktok.com/@superchatspod Playlist of music: https://www.youtube.com/playlist?list=PLp6uXoGNUwk9Tq0NWOwaCLGruX0XdVBfd 00:00:00 Intro 00:03:07 Miwa's Birthday Concert 00:09:20 Bae's Birthday 3D Live 00:26:23 Kaminari Clara Graduated 00:43:42 Octavio's Tribute to His Mom 00:51:43 ENReco Part 3 Announced 00:54:30 Suisei's Playing Factorio 00:56:36 Clotho's Graduation Announced 00:58:20 VAllure Gen 3 Auditions Soon! 00:59:23 Mint's Gonna Be In An Anime 00:59:55 Dr Nova(e) Plushie Up For Sale 01:01:21 Advent's New Merch 01:03:28 Youtube's Big Glitch 01:05:56 Tenma's Ratatan Tourney 01:07:22 Eva Ananova's Redebut 01:08:40 Bae's Snake Eyes 01:10:28 Momosuzu Nene's Liminal 01:12:30 Marine and Suisei's Chatter Chatter 01:13:37 Advent's What Goes Around 01:14:17 Matsuri's Album - Chasing the Dream 01:15:08 Shyfruits' Fruits Parade 01:16:01 Midnight Grand Orchestra is still Great 01:19:02 Kizuna AI Kamacho 01:23:52 Clara Until the Afterlife 01:24:36 Bri Number One 01:26:20 Reine Soiree 01:27:14 Hakka Palette 01:27:53 Miori Ch4nge 01:31:14 Eva Ananova Panic 01:32:22 Alicja SOTN 01:33:31 Elizabeth ASMR 01:34:41 Dr Nova's Child 01:36:24 Dr Nova Menhera 01:39:11 Paige Terner's Funeral (not her's) 01:44:30 Bae Minesweeper 01:46:12 Poma's Viral Stream 01:57:27 Randon Unc Slop Diabolo 2 Stream 01:58:32 Community and Shilling 02:01:55 Birfdays
Bryan and Anderson review Song Sung Blue, Rats! Is This Thing On? The Life of Chuck and Bottle Conditioned (from assigner Bryan McCulley). Then the boys celebrate the beautiful game with Robert Cordova's topic: Top 5 Soccer Movies! Loaded for Bear New Promo Video! The Film Vault on Youtube TFV Patreon is Here for Even More Film Vault Anderson's new doc: Loaded for Bear Atty's Antiques Baldywood Newsletter COMEDY CONFESSIONAL Listener Art: Benjamyn Lockwood Featured Artist: Ben Yonda The Film Vault on Twitch Buy Bryan's Book Shrinkage Here The Film Vaulters “Kubrick is Everywhere” Shirt CONNECT WITH US: Instagram: @AndersonAndBryan Facebook.com/TheFilmVault Twitter: @TheFilmVault HAVE A CHAT WITH ANDY HERE ATTY & ANDY: DIRECTED BY A FOUR-YEAR-OLD Subscribe Atty and Andy's Youtube Channel Here THE COLD COCKLE SHORTS RULES OF REDUCTION MORMOAN THE CULT OF CARANO Please Give Groupers a Rotten Tomatoes Audience Score Here Please Rate It on IMDB Here The Blu-ray, US The Blu-ray, International Groupers is now available on these platforms. On Amazon On Google Play On iTunes On Youtube On Tubi On Vudu Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome back to Young Hot Guys! This week we hear all about Killian's life-changing, trip to Istanbul, his new Marseille apparently. Shane's been ratted out by you, our very own listeners for talking about Ariel on the podcast, and Tony fully embraces his inner cat-holic this Ash Wednesday. To get extra bonus content and ad-free listening join HeadStuff+ here: https://headstuffpodcasts.com/membership/ Shane's Tickets: https://linktr.ee/shanedanbyrne Killian's Tickets: https://linktr.ee/killiansundermann Tony's Tickets: https://linktr.ee/tonyhorror Shane Daniel Byrne, Tony Cantwell, and Killian Sundermann are Young Hot Guys. This is a HeadStuff podcast produced by Hilary Barry. Artwork by Shane Kenna. Contact us at yhg@headstuff.org
Drs. Peter Goldstein, Ken Solt and Gwi Park discuss the article "Pharmacologic Reversal of Xylazine-Induced Unconsciousness in Rats" published in the March 2026 issue of Anesthesia & Analgesia.
If you like what you hear, please subscribe, leave us a review and tell a friend!
John Endres and Nicholas Lorimer discuss the latest on the battle for Joburg. They also discuss the ANC sending condolences to Iran. And they discuss the court action against News24 for what they published on a Gauteng mayor. Website · Facebook · Instagram · Twitter
Lassa fever is back in the headlines and in hospitals.As Nigeria moves deeper into 2026, fresh data from the Nigeria Centre for Disease Control and Prevention shows a troubling rise in confirmed cases and deaths across several states. Behind the numbers are families grieving, health workers under pressure, and communities once again confronting a disease that has become a seasonal threat.Why are infections increasing? Are response efforts enough? And what must Nigerians do differently this time?Today on Nigeria Daily, we unpack the rising cases, the government's response, and what this means for you.
Things take a bit of a turn in the third hour when Tobin declares that Smash Burgers are a scam, the gang seems to mirror his opinion except Brittney which of course turns into a quibble about what the best burgers are. We pause the burger talk when news strikes that the Panthers have signed a goalie to a 2 way contract which causes Tobin to absolutely spiral because this be the beginning of the end of Sergei Bobrovsky with the Panthers. Then it is time for our favorite Wednesday game Rats Off A Ship!; Number one picks going back to school, Dolphin trades, and Reese's new competition!
This week, we're stealing a couple hours of your time to discuss The Rats: A Witcher Tale, the prequel movie that dropped at the same time as Season 4 and is designed to be watched after it…despite taking place well before. (The Witcher's up to its timeline shenanigans again, it seems.) Paired with the perfectly-themed Master of the Thieves Guild Blended Bourbon by Quest's End Whiskey, we keep things loose, lively and liquidated as we unpack the plots—meaning both the film's narrative and the Rats' plot to steal loads of cash—and try to figure out just what happened to this thing behind the scenes. Also, we come out in favor of bathing with a drunken Dolph Lundgren, debate the role of cephalopods in sex dens and reveal why when it comes to spider women, most movies just like to tease.
Dr. Deb Muth 0:00 Welcome back to Let’s Talk Wellness Now. I’m your host, Dr. Zab, and we are continuing our discussion this week on 0:08 peptides. And so, if you haven’t heard our first conversation about peptides, 0:13 please go back and look at that episode. We talk all about the manufacturing, the safety, the quality of peptides, and we 0:20 dove into GLP1s. And today we’re going to dive into peptides for sexual 0:26 wellness, immune function, growth hormone, and all the amazing fun things 0:32 we can do with peptides. So, as usual, grab your cup of coffee or tea, settle 0:37 in, and let’s talk wellness now. And we’re going to take a short pause from our sponsor. I know we’ve got to do 0:44 that, you guys. They’re who keep us on the air. So, I’m going to pause for just a minute and be right back after this 0:50 message from our sponsor. Ladies, it’s time to reignite your vitality. Primal 0:56 Queen supplements are clean, powerful formulas made for women like you who want balance, strength, and energy that 1:03 lasts. Get 25% off at primal queen.com. Serenity Health. That’s primalqueen.com. 1:10 Serenity Health. Because every queen deserves to feel in her prime. All 1:15 right, everybody. We are back. And are you ready? We are talking all things peptide and I am opening the show today 1:23 with sexual wellness. Yes, I’m going there, you guys. I am going there. You 1:29 know, this has really become a big issue for people um of all ages. It’s not just 1:3 4us older people. It’s younger people, too. And there’s a whole variety of reasons why we have sexual dysfunction. 1:42 And when we’re talking about sexual dysfunction, we’re not just talking about it doesn’t work, right? Or I can’t 1:48 reach orgasm. A lot of it is around desire and um the thought of it and 1:54 wanting to connect, wanting to be kinder to one another, wanting to be touching 2:00 one another. A lot of it resolves or revolves around that. And so there are some peptides that can help us and I’m 2:08 really excited to be able to talk about those today. So the first one is called PT-141. 2:14 This targets the brain not the periphery. Right? So for many women I 2:20 will always tell you sex starts between here. It is a brain thing for us. It is 2:26 not necessarily a physical thing. For guys that’s a little different. It’s very physical. For women it’s all in our 2:32 brain. So tip for you men that are listening. You have to prime your woman’s brain first if you want her to 2:38 have sex with you that night. You have to be nice to her. You have to bring her flowers. Do the dishes for her. Do 2:45 something kind. Bring her a cup of coffee or tea or a glass of wine. Take her to dinner. You have to woo her. And 2:51 I don’t care how long you’ve been married. That has to happen. And tip number two, don’t say anything stupid 2:57 that day. I’m just being honest. When you guys say things that make us upset, 3:03 that lingers with us for the rest of the day. And it’s it’s a turnoff for us. And 3:08 for a lot of women, we can’t get past that when it comes time to snuggle at night. And sex doesn’t always have to be 3:14 at night either. So, you can tell I really love talking about this conversation, but we’re going to get into the peptide part of it because this 3:21 is going to help people. So, um, PT-141 is marketed as I’m going to slaughter 3:28 this name, Vali, and it represents a fundamentally different approach to 3:34 sexual dysfunction than the PDE5s inhibitors like Slenden, Viagra, 3:40 Tedataphil, which is Seialis. And while the PDE5 inhibitors work specifically by 3:47 enhancing blood flow to the genital tissues, PT-141 works centrally in the brain by 3:54 modulating neural s neural circuits involved in the sexual desire and 4:00 arousal. Now PT-41 is a cyclic hpatipeptide. It’s seven amino acid 4:07 peptide arranged in a cyclic structure that acts as a melanoortin receptor 4:13 agonist and with particularly the infinity for MC3R and MC4R subtypes. 4:20 It’s actually a metabolite of the melanotan 2, a peptide originally 4:26 developed for tanning that was also found to enhance sexual desire in early 4:31 studies. Now the melanoortin system in the brain is involved in multiple functions including energy homeostasis 4:39 but it also is involved in sexual motivation and arousal behaviors. The FDA approved PT-141 in 2019 specifically 4:48 for the treatment of acquired generalized hypoactive sexual desire 4:54 HSDD in permenopausal women. So for the first time we have a medication that was 5:01 approved by the FDA to use for women for sexual dysfunction. We have had all of 5:07 these seialis tedataphil viagros for men but we had nothing for women. And so 5:12 this is amazing that this is available for women and approved by the FDA. It’s a big deal. This represents the first 5:19 and only FDA approved medication specifically targeting these circuits of sexual desire rather than the peripheral 5:27 arousal mechanisms. And this indication is quite specific, meaning it was developed at some point, not lifelong. 5:35 So I if you’ve had sexual dysfunction your entire life, this medication was 5:40 not approved for you. But if it’s something that you developed over time, like when you went through pmenopause or 5:46 menopause or some women have this experience happen after childirth, that’s what we’re talking about here. 5:53 Now, it’s also not just um supposed to be used if you dislike your partner, 5:59 right? If your relationship is bad and you dislike your partner, this probably isn’t going to fix a ton. It might help 6:05 a little bit, but that’s not what it’s meant for. So, you really have to know what you’re using it for and why. And 6:11 the other thing that I would say is this is something that we don’t go to if your hormones are not balanced properly. You 6:17 have to balance your hormones properly before using something like this because it still may not work. Now, the only 6:24 caveat to that is if you’re a woman that has a risk of breast cancer and can’t use hormones, then that’s a different 6:31 story and we would have that conversation about whether or not this medication would be appropriate for you. Now, the FDA label specifies PTA1 uh 6:39 PT-141 as it not being indicated for HSDD in causes where low sexual desire 6:46 is due to coexisting medical or psychiatric conditions, problems with relationships, like we had talked about, 6:53 side effects to medications or other substance use. This specifically reflects the importance of differential 6:59 diagnosis. Low sexual desire can have many root causes and PT-41 is only 7:05 appropriate when those causes have been ruled out. Now, I have I used PT41 in 7:10 people who have sexual dysfunction issues as a result of using 7:16 anti-depressants. Yes, I have. I’ve used Flynn in that effect as well. And it 7:21 does work sometimes, but it doesn’t work completely. But you need to know that that is not what the approval is for the 7:27 FDA. So that is done in something that we call off label use. So very important 7:33 to know. Now in these clinical trials leading to FDA approval, this was published by Kinsburg and colleagues in 7:40 obstetrics and gyne gynecology in 2019. PT-141 demonstrated statistically 7:46 significant improvements in sexual desire and decreases in distress related 7:51 to low desire compared to placebo. The effects manifest over 45 minutes to 7:56 several hours after the injection and the mechanisms involved modulation of dopamine and melanoorton pathways in the 8:04 hypothalamus and the brain regions that involved sexual motivation. Now cardiovascular effects of PT 141 require 8:12 careful attention. This drug causes transient increases in blood pressure about 3 to four points and transient 8:20 decreases in heart rate. And because of this, it is contraindicated in patients 8:25 with uncontrolled hypertension or known cardiovascular disease. And it has been studied in patients who’ve had recent 8:32 cardiovascular events or sorry hasn’t been studied hasn’t been studied in patients who’ve had recent 8:39 cardiovascular events. So patients need to have their blood pressures checked before starting therapy. Nausea is 8:45 extremely common. It is one of the biggest things I often will tell people to take an anti-nausea medicine if 8:52 they’re going to do this because the last thing you want to do is inject this medication and think it’s going to give 8:57 you this great time with your partner and you’re so nauseated that you can’t even perform, don’t want to kiss, don’t 9:05 want to do anything. It it can be pretty profound for some people. um it does affect about 40% of the patients in 9:12 clinical trials which is why many clinicians require or recommend an 9:17 anti-nausea medication like I had just said other common adverse effects include flushing injection site 9:24 reactions headache in about 13% of the population which I have seen worse if 9:30 people are prone to headaches and the headaches are pretty intense so I will also have them premedicate if they have 9:36 that um sensitivity ity with a Tylenol or Advil, Alie, whatever it is they 9:42 typically use for their headaches to help prevent that from occurring. Now, some patients also experience a 9:50 generalized hyperpigmentation of their skin, particularly in areas with chronic friction, and this may not be reversible 9:57 after discontinuation. So from an integrative perspective, PT-41 10:03 represents one tool in addressing female sexual dysfunction, but it should never be the first or only intervention. And 10:11 low sexual desire in women is complex. Multiffactorial involving hormonal imbalances, low testosterone, estrogen 10:18 deficiency, progesterone imbalances, thyroid dysfunction, adrenal dysfunction, and with elevated or 10:24 disregulated cortisol levels, sleep deprivation, relationship issues, unresolved trauma, including sexual 10:31 trauma, chronic pain, body image concerns, and medication side effects such as SSRIs are notorious for this. So 10:39 a comprehensive hormone panel including total and free testosterones, estradile, 10:45 progesterone, DHEA, thyroid function in cortisol assessment, ideally four-point 10:51 cortisol, salivary should precede any pharmacological intervention. And additionally, addressing the 10:57 psychological component and relationship dimensions through appropriate therapy is necessary. I have a lot of patients 11:03 that say, “This is just too much work for sex. I don’t want the side effects. I don’t want to deal with this.” and that’s totally fine. But for some 11:09 people, their sexual dysfunction is actually causing more problems on their 11:14 relationship and they want to do something to fix that. And just know that if you’re using a peptide like this 11:20 that comes with some of these side effects and you have to premedicate for it, it is not the end of the world. Um, 11:27 but it may be a possibility that you may need that. So, let’s dive into body composition and growth hormone access. 11:34 So Tesmarellin is the only FDA approved GH 11:40 analog. Tesarelin is marketed as Agrifta and Agria SV. It is a synthetic analog 11:48 of human growth hormone releasing hormone. So GH RH human growth hormone 11:53 releasing hormone. These things are such long names it’s confusing and it’s difficult to spit out, right? It 11:59 consists of 44 amino acids. The structure is identical to our own 12:05 body’s growth hormone GHR um with the addition of trans3 hexonol group which 12:14 stabilizes the molecule that extends its half-life compared to the native GHR. 12:19 The mechanism of tesmarellin is elegant in its preservation of physiological 12:24 growth hormone GH secretion patterns and rather than administering an exogenous 12:30 growth hormone directly, tesmarillin binds to the GH receptor in the anterior 12:36 pituitary gland stimulating the indogenous pulsatile release of GH. So 12:42 you know it it’s slower in that stimulation and it pulsates instead of a direct rise and fall. This pusile 12:49 pattern more closely mimics natural GH secretion which occurs in bursts 12:54 primarily during sleep. The GH then stimulates the liver to produce insulin-like growth factor IGF-1 which 13:01 exerts many of the downstream metabolic effects including lipolytic effects on 13:07 the atapost tissue. So fat atapose and how we break that down. The FDA approved 13:13 tesmarellin in 2010 for a very specific narrow indication, the reduction of 13:19 excess abdominal fat in HIV infected patients with lipodistrophe. This 13:25 condition characterized by abnormal fat redistribution with accumulation of visceral body fat and the loss of 13:32 subcutaneous fat in face and limbs developed as a complication of an 13:37 antiviral therapy particularly with older protease inhibitor reg uh 13:42 regimens. The visceral fat accumulation in patients is not just cosmetic. It’s associated with increased cardiovascular 13:49 risk, insulin resistance, and inflammatory markers. The pivotal trial that led to the FDA approval included 13:56 work by Stanley and colleagues published in the annuals of internal medicine in 2014. It demonstrated that tesmarillan 14:03 significantly reduced the visceral atapose measured by CT scan by approximately 15 to 20% which is a 14:10 significant difference to placebo over a short period of time only 26 weeks. Now, 14:16 interestingly, the total body uh weight typically remained stable or even 14:21 increased slightly as the reduction of visceral fat was sometimes offset by increases in lean body mass or 14:28 subcutaneous fat. This highlights an important point. Tesmearellin is not a weight loss drug in its conventional 14:34 sense. Its effects are specifically on body composition and fat redistribution. 14:40 Now the glucose metabolism effects of tesmarellin do require careful monitoring because GH and IGF1 can 14:47 induce insulin resistance. Tesmearellin can increase glucose levels and hemoglobin A1C and in these clinical 14:54 trials glucose tolerance and new onset diabetes occurred in some patients. So 14:59 this creates a therapeutic paradox while res reducing visceral fat we should theoretically improve metabolic health. 15:07 The GH mediated insulin resistance can worsen the glycemic control and patients 15:12 with diabetes require particularly close monitoring. The potential need for adjustment in diabetic medications can 15:19 occur. So I already know what you guys are thinking. Can I use Tesmarellin and 15:24 GLP1 at the same time? And the answer is yes. Especially in those people that we 15:30 know have an insulin resistance already or are prone to that, we can use lowd 15:36 dose micro doing GLP-1 along with tesmarellin to help prevent this from 15:42 occurring um or reduce the risk of it occurring. Now there are some other adverse related problems to growth 15:49 hormone access which include fluid retention which can uh manifest as uh 15:55 ankle swelling, joint pain, muscle pain, paristhesas, carpal tunnel syndrome is 16:01 common to see. Of course you can always see injection site reactions reported about 26 to 30% of the time in the trial 16:08 participants. And this also theoretically has a concern about IGF-1 elevation potentially promoting 16:14 malignancy through long-term data is limited. So we have to be cautious about 16:20 this but it is a growth hormone and anything that is a growth hormone can cause cells to grow and it cannot 16:26 necessarily differentiate between healthy cells and bad cells. So the drug is contraindicated is contraindicated in 16:33 patients with active cancer and in patients with the disruption of the HPA access from conditions like pituitary 16:40 tumors, pituitary surgery, head of radiation um and traumatic brain injury. 16:46 Now off label use of tesmarellin for general anti-aging or body composition 16:51 optimization in non-HIV population, it doesn’t have FDA approval. There is no 16:58 FDA studies. um that promote this, but practitioners do prescribe it for these 17:04 purposes under an experimental and not supported by FDA approved indications. 17:10 And um from an integrative medical standpoint, optimizing natural growth 17:15 hormone secretion through lifestyle interventions, high quality sleep is important. GH primarily is excreted 17:22 during sleep and deep sleep waves. So improving your deep sleep is important. Intermittent fasting can also increase 17:28 growth hormone by five-fold as demonstrated in a Hartman and colleagues uh study from the journal of clinical 17:35 endocrinology and metabolism in 1992. And highintensity interval training, adequate dietary protein, blood sugar 17:42 control, these all can help naturally increase your growth hormone. So, let’s 17:47 dive in now and talk about bone health. peptide hormones um such as oh I’m gonna 17:54 I’m gonna really slaughter this name. Terraparatide is a true bonebuilding 18:01 peptide. It’s marketed as forio. It’s a recumbent form of the first 34 amino 18:08 acids out of 85 of the human parathyroid hormone PTH. It represents a unique 18:13 approach to osteoporosis treatment because it’s one of the few truly anabolic anabolic bone therapies meaning 18:21 it actively binds new bone rather than simply preventing bone loss. The biology 18:26 of parathyroid is fascinating and seemly contraindicated or uh contradictory. 18:32 Continuously sustained elevations of PTH as occurs in hyperarathyroidism 18:37 is catabolic to bone. So people who have hyperarothyroidism typically have significant bone loss 18:44 especially before it’s diagnosed and it causes causes increased bone 18:49 reabsorption loss of bone density increased fracture risk and however 18:55 intermittent exposure to PTH as achieved with once daily uh injections of forio 19:01 has the opposite effect. This intermittent exposure preferentially stimulates osteoblasts bone building 19:08 cells over osteoclasts bone reabsorbing cells and it leads to 19:13 the net bone formation. So terraparatide binds to the PTH receptors on 19:20 osteoblasts and renal tubular cells in bone. It increases the number of 19:25 activity of osteoblasts stimulating the differentiation of osteoblast precursor cells and may 19:32 reduce osteoblast apoptosis basically programmed cell death allowing this bone 19:37 building cell to work longer. The result is increased bone formation, improved bone architecture and tbacular 19:45 connectivity and ultimately increased bone mineral density um particularly in the hip and the spine which is so 19:51 difficult to regain. The FDA approved this medication in 2002 based on pivotal 19:57 studies by Near and colleagues published in the New England Journal of Medicine in 2001 which demonstrated significant 20:05 reductions in vertebral and non-vebral fractures in post-menopausal women with 20:11 osteoporosis. specifically uh reduced new vertebral fractures by 20:17 65% and nonvettebral fragility fractures by 53% 20:23 compared to placebo over a median followup of 21 months. This is really 20:29 incredible because we have not seen this kind of um change uh in other 20:35 medications that we’ve used for osteoporosis. So current FDA approval 20:40 indicates uh this for post-menopausal women with osteoporosis at high risk for 20:46 fracture, men with primary or hypoconatal osteoporosis at high risk for fracture 20:53 and men and women with glucocord cord glucocordide 21:00 induced osteoporosis at high risk for fracture. The high risk qualifier is 21:05 important. uh terrapeptide is reserved for patients with severe osteoporosis, 21:11 multiple fractures, very low low bone density and those who have failed or are 21:16 intolerant of other therapies. The most significant concern for this medication 21:21 is highlighted in a boxed warning with rat toxicology studies where it caused 21:27 osteioaroma which is a bone cancer in a dose dependent and treatment duration dependent manner. The revolence of this 21:34 finding to humans is debated. Rats have fundamentally different bone biology than humans with continuous bone growth 21:41 throughout life and different PTH receptors. Now post marketing 21:46 surveillance in humans hasn’t shown a clear increase in osteocaroma risk but 21:51 theoretically concerns persist and because of this terapeptide is 21:57 contraindicated in patients at risk baseline risk for osteioaroma 22:02 including those with pageantss disease of the bone unexplained elevations of alkaline phosphate prior skeletal 22:10 radiations bone metastases or skeletal malignancies and pediatric patients or young adults 22:16 with open hyes. There’s also a lifetime treatment duration of only 2 years and 22:22 terrapeptide can cause transient hypercalcemia. So an elevated blood calcium and as PTH normally increases 22:31 calcium levels by enhancing bone reabsorption, increasing renal calcium 22:36 reabsorption and promoting activation of vitamin D which increases intestinal calcium absorption. Some patients 22:43 experience orthostatic hypotension within 4 hours of injecting requiring 22:48 caution in at risk populations for blood pressure. Common side effects include 22:53 muscle pain, joint pain, pain in the limbs, nausea, headache, and dizziness. So from an integrative bone health 23:00 perspective, terrapeptides should be part of a comprehensive strategy. Adequate calcium intake, 500 to a,000 23:08 milligrams of calcium a day from food and supplements combined. and vitamin D. 23:13 Getting vitamin D levels of at least 50 to 80 are essential for the drug to work 23:20 optimally. But beyond this, bone health requires vitamin K2, which directs calcium into the bones rather than soft 23:27 tissues, magnesium as a co-actor in bone metabolism, trace minerals like boron, 23:33 copper, silica, and of course, adequate protein intake, which many of us, especially as women, don’t do 0.8 8 to 1 23:42 gram of protein per kilogram of body weight, weightbearing exercise. Of 23:47 course, these all provide mechanical signals that complement the biochemical 23:52 symbol uh signals of terrapeptide. Sequential therapy is also critical. The 23:58 bone mass gains from terraparatide can be lost if patients don’t transition to 24:05 an anti-resorbbitive agent a bisphosphinate after completing this therapy and the anabolic effects to 24:12 build bone but maintaining the new bone requires preventing excess reabsorption. 24:18 So positive things about this but there are definitely some concerns as well. So 24:23 the next one we’re going to talk about is Lu Prolrooide. It is marketed under 24:29 the multiple brand names of Lupron, Depo, Eligard, and it’s a synthetic 24:34 nonapeptide analog of naturally occurring ginonadotropen releasing 24:39 hormone G&R, also called luteinizing hormone releasing hormone, LHR. 24:46 It’s a fascinating example of how manipulating natural hormonal feedback systems can create therapeutic effects. 24:53 So, G&RH is normally secreted in a pulsatile fashion by the hypothalamus 24:59 and travels to the anterior pituitary where it binds to G&R receptors and 25:05 stimulates the release of luteinizing hormone LH and follical stimulating hormone FSH. These ginatotropins signal 25:13 the ovaries or the testes to produce sex hormones, estrogen, progesterone in 25:18 women, testosterone in men. Uh, luoprololi lupron as a GNR agonist 25:26 initially mimics the action of natural G&R causing an acute flare response with 25:33 uh increased LHFSH secretion which temporarily increases sex hormone 25:38 production. However, the continuous administration which is in the depo 25:44 formulations, the GNR receptors in the pituitary become desensitized and 25:50 downregulated. And after about 2 to four weeks of continuous exposure, LH and FSH 25:56 secretion is profoundly suppressed, leading to what’s termed as chemical 26:01 castration. Testosterone levels in men drop to castrated levels less than 50 26:08 and estrogen production is marketkedly suppressed in women. This bifphasic 26:13 response creates both therapeutic applications and management challenges in prostate cancer where tumor growth is 26:20 typically androgen dependent and the ultimate goal is testosterone suppression. However, the initial 26:27 testosterone surge during the flare phase can temporarily worsen symptoms potentially causing increased bone pain, 26:34 urinary obstruction, or even spinal cord compression in patients with metastatic 26:40 disease. This is why uh luoprolide is often started with an anti-ad androgen 26:47 like bicladamide for the first two to four weeks to block the effects of the 26:52 testosterone surge. The FDA has approved lupalide for multiple indications across 26:59 formulations. In oncology, it’s used for palletive treatment of advanced prostate cancers. In gynecology, various 27:06 formulations are approved for endometriosis, for pain management and lesion reduction and for fibroids. 27:13 Typically for pre-operative uh hematological improvement in anemic patients. In pediatrics, it’s used for 27:20 central precocious p puberty basically to halt the premature sexual development of these young people. Now, there are 27:28 adex uh adverse effect profile that reflects profound hormonal suppression. 27:34 In men treated for prostate cancer, hot flashes affect about 59% of the patients. Other common effects include 27:41 general pain, swelling, bone pain. Um long-term use of these medications leads 27:47 to metabolic changes. It increases fat mass. It decreases lean mass. It worsens 27:53 insulin sensitivity, disrupts the cholesterol uh lipid panels, increases 27:59 diabetic risk, has some concerns over cardiovascular disease. And the metaanalysis have shown increased risks 28:06 of heart infarction, myocardial inffection, sudden cardiac death, and stroke in populations receiving 28:13 long-term androgen deprivation therapy. The bone effects are particularly dramatic. Without sex hormones, bone 28:20 density decreases significantly, typically 3 to 4% per year during the 28:26 first two to three years of therapy. And this bone loss may not fully be reversible after the the therapy 28:32 discontinues. The American Society of Clinical Oncology recommends bone density monitoring and consideration of 28:39 bisphosphinates uh in men receiving long-term androgen deprivation. In women treated for 28:46 endometriosis or fibroids, the estrogen suppression creates a hypoestrogenetic state similar 28:54 to menopause. Hot flashes affect 90% of patients with other common effects 29:00 including headaches, emotional irritability, decreased sex drive, vaginal dryness, bone density loss. And 29:08 because of these bone concerns and treatment duration with endometriosis, typically limited to six months, though 29:14 some formulations allow for longer use with adback hormonal therapy to 29:20 partially mitigate these side effects. The mood and cognitive effects can be s 29:25 significant. I’ve seen it over the years. the depression, the memory impairment, difficulty focusing and 29:31 concentrating. It can be very very traumatic and the quality of life that 29:37 happens for these uh women and men can be unbearing for many of them. Um, from 29:44 an integrative perspective, patients receiving this medication need comprehensive support care. Bone health 29:51 interventions using calcium, vitamin D, vitamin K2, weightbearing exercise, 29:58 cardiovascular risk management becomes critical, including blood pressure monitoring, lipid management, diabetes 30:05 screening. For hot flashes management, some patients respond to black coohos, 30:10 sage, or vitamin E. Though evidence is mixed and individual response varies, 30:16 omega-3s may help with the mood and the inflammation, resistance training becomes specifically important to 30:22 preserve lean muscle mass in the face of hormonal suppression. 30:27 Now there’s something called calcetonin salamon which is marketed as miaelin. 30:34 It is a nasal spray. It is now discontinued. And foral is the new 30:39 synthetic polyeptide hormone of 32 amino acids identical to calcetonin of salamon 30:47 origin. It represents an interesting case study in how initial promise gives 30:52 way to safety concerns that regulate a therapy to historical footnote status. 30:58 Calcetonin is naturally occurring hormone in humans. It’s secreted by the paraphalicular sea cells in the thyroid 31:04 gland. Its primary physiological role is to lower blood calcium levels by 31:10 directly inhibiting osteoclast activity, reducing bone reabsorption, increasing 31:16 renal calcium secretion or excretion, and possibly reducing the intestinal 31:21 calcium absorption. So, salamon calcetonin is used therapeutically because it’s more potent and longer 31:27 acting than human calcetonin. The FDA initially approved calceton and salmon 31:34 for several indications post-menopausal osteoporosis in women more than five 31:39 years post-menopausal when alternative treatments are not sustainable. Padet’s 31:44 disease for bone and hypercalcemium as emergency treatments. The nasal spray formulation is particularly popular for 31:53 osteoporosis because it offered a non-injectable alternative to bisphosphinates. 31:58 However, in 2012, the European Medicine’s Agency, EMA, conducted a 32:05 comprehensive safety safety review after a poolled analysis of 21 clinical trials 32:10 involving over 10,000 patients showed a statistically significant increase in 32:15 malignancy risk in patients treated with calceton salamon compared to compared to 32:21 placebo. The overall malignancy rate was 4.1% in calcetonin treated patients 32:28 versus 2.9% in placebo patients. The types of cancer 32:34 varied with no single cancer type predominating, making it difficult to establish a clear mechanistic link. 32:41 However, the signal was concerning enough that the EMA restricted the use of calcetonin containing medicines. In 32:48 the United States, the FDA issued communications about malignancy signal and conducted its own review. While they 32:56 didn’t fully withdraw the drug, the cons consensus shifted dramatically. The nasal spray formulations miaelson was 33:03 voluntarily discontinued by the manufacturer and current clinical practice guidelines now consider 33:10 calcetonin salamon as a second line or lower option for osteoporosis. While 33:15 behind bisphosphinates, dennism mob, uh, terrapeptide, the analesic effect of 33:21 calcetonin in bone pain, particularly in acute vitibbral, uh, compression 33:26 fractions from osteoporosis or pageantss disease may still provide a role for short-term use in these selected 33:32 patients. The mechanism of this pain relief is unclear, but may involve 33:38 effects of endorphin systems and/or direct actions on pathways. The history serves as an important reminder in 33:45 peptide medicine. Initial approval and early clinical use does not guarantee 33:50 long-term safety effects. Post marketing surveillance and poolled analysis of the clinical trial data can reveal adverse 33:58 effects that weren’t apparent in initial studies. It also underscores why newer 34:04 agents with better safety profiles um have largely replaced calcetonin in 34:10 clinical practice. So this is really an important thing. Not one thing stays the same forever. We have to change as we 34:18 identify new and better products as we identify problems and concerns. I will 34:24 always tell my patients if you are uncertain of taking a new drug which we 34:30 all should be wait five years. Within five years we are going to find the 34:36 problems that they didn’t find in the clinical studies. Remember, a lot of these clinical studies are small, small 34:43 groups, short periods of time. It’s expensive to do these trials. So, if you 34:49 wait for five years, in the first two to three years, you will see the problem start to emerge. And what are you going 34:55 to look for? You’re going to look for the the news um commercials from lawyers 35:02 suing a drug. And they will tell you what the problem is. and then you can decide, is this something that I want to 35:09 use or not. Don’t jump on bandwagon and be the first one to do this, especially 35:14 if you’re sensitive. You know, give it time so you can see exactly what’s going on. So, I’m going to end our show on 35:22 this and we are going to pick up on part three of peptide therapy in our next 35:28 segment where we’re going to talk about the investigational peptides and some 35:34 exciting things that are happening with that. So, I want to thank you for joining me today on Let’s Talk Wellness 35:39 Now. It’s always a pleasure having a conversation with you guys and I hope this brings value to you with what we’re 35:45 talking about. If you have ideas for topics that you want me to discuss, 35:51 please message us, you can share your comments on Facebook, you can email us, 35:58 um you can get a hold of us however you would like to share that. I do look at the comments below in the episodes as 36:04 well. So you can place your comments there. And once again, one of the best things you can do for me is like, 36:11 subscribe, and share so that we can spread the messages of what we’re doing. 36:16 I do this at no cost. I don’t make any money out of this. I do this as an 36:21 educational purpose for everybody else. I love doing it, but it really helps us 36:28 on the algorithms if you would be just willing to like, subscribe, and share. 36:33 So, thank you for spending your time with me. I know time is important.The post Episode 257 – Peptides for Sexual Wellness & Hormonal Health: PT-141, Growth Hormones, Bone Health & More! first appeared on Let's Talk Wellness Now.
In this episode of GardenDC: The Podcast about Mid-Atlantic Gardening, we talk with illustrator and author Halsey Berryman, all about her new book, Pests & Other Friends*. The plant profile is on Wallflowers and we share what's going on in the garden as well as some upcoming local gardening events in the What's New segment. We close out with the Last Word on "Growing Kale in Pots" from Christy Page of GreenPrints.*You can order Halsey's book, Pests & Other Friends, at https://amzn.to/4r0m1hF This link is to our Amazon affiliate accounts and we may earn a few pennies from their sales, but this does not impact your purchase price.BTW, YOU can become a listener supporter for as little as $0.99 per month! See how at: https://creators.spotify.com/pod/show/gardendc/subscribeIf you liked this episode, you may also enjoy listening to:~ GardenDC Podcast Episode 198: Rats and Other Destructive Crittershttps://washingtongardener.blogspot.com/2024/06/gardendc-podcast-episode-198-rats-and.html~ GardenDC Podcast Episode 174: Wildscapinghttps://washingtongardener.blogspot.com/2023/11/gardendc-podcast-episode-174-wildscaping.html~ GardenDC Podcast Episode 50: Deer-Resistant Native Plantshttps://washingtongardener.blogspot.com/2021/03/gardendc-podcast-episode-50-deer.htmlShow Notes will be posted after 3/10/2026.We welcome your questions and comments! You can leave a voice mail message for us at: https://podcasters.spotify.com/pod/show/gardendc/message Note that we may use these messages on a future episode.And be sure to leave us a 5-star review on your favorite podcast platform plus share us on social media with #GardenDC, so other gardeners can find us too!Episode Credits:Host and Producer: Kathy JentzMusic: Let the Sunshine by James MulvanyRecorded on 2-28-26.
Barnaby brings all the latest news from Tottenham HotspurSubscribe to my Patreon account to support me making Tottenham daily content here:https://www.patreon.com/BarnabySlaterPatreonWatch on YouTube:https://www.youtube.com/@barnabyslater_Instagram: @barnabyslatercomedyTikTok Football: @barnabyslaterTikTok Spurs: @barnabyslatercoys Hosted on Acast. See acast.com/privacy for more information.
Bush rats are not black rats — that's the first thing you need to know.Ann Jones is joined by ABC Top 5 scientist Dr Patrick Finnerty to understand why researchers are going around sniffing bush rats — and how it might help reintroduce them to Sydney's nature reserves.Find out more about the Top 5 science media residency here.Featuring:Dr Patrick Finnerty, conservation ecologist at the University of SydneyProfessor Peter Banks, conservation ecologist at the University of SydneyAssociate Professor Thomas Newsome, conservation ecologist at the University of SydneyMareshell Wauchope, PhD student at University of SydneyProduction:Ann Jones, Presenter / ProducerRebecca McLaren, ProducerHamish Camilleri, Sound EngineerThis episode of What the Duck?! was produced on the land of the Eora and Kulin Nations.Find more episodes of the ABC podcast, What the Duck?! with the always curious Dr Ann Jones exploring the mysteries of nature on ABC Listen (Australia) or wherever you get your podcasts. You'll learn more about the weird and unusual aspects of our natural world in a quirky, fun way with easy to understand science.
Bryan and Anderson review Pillion, The Outfit, Blue Moon, Rental Family, Miracle: The Boys of ‘80 and Rats!. Then the boys count down their Top 5 Worst Characters to Have As Roommates! Loaded for Bear New Promo Video! The Film Vault on Youtube TFV Patreon is Here for Even More Film Vault Anderson's new doc: Loaded for Bear Atty's Antiques Baldywood Newsletter COMEDY CONFESSIONAL Listener Art: Jonathan Oxorn Featured Artist: The Atomic Aces The Film Vault on Twitch Buy Bryan's Book Shrinkage Here The Film Vaulters “Kubrick is Everywhere” Shirt CONNECT WITH US: Instagram: @AndersonAndBryan Facebook.com/TheFilmVault Twitter: @TheFilmVault HAVE A CHAT WITH ANDY HERE ATTY & ANDY: DIRECTED BY A FOUR-YEAR-OLD Subscribe Atty and Andy's Youtube Channel Here THE COLD COCKLE SHORTS RULES OF REDUCTION MORMOAN THE CULT OF CARANO Please Give Groupers a Rotten Tomatoes Audience Score Here Please Rate It on IMDB Here The Blu-ray, US The Blu-ray, International Groupers is now available on these platforms. On Amazon On Google Play On iTunes On Youtube On Tubi On Vudu Learn more about your ad choices. Visit megaphone.fm/adchoices
Looking for great fantasy & historical fiction for Middle Grades and YA readers that won't constantly clash with Christian beliefs and values?After several recent episodes focused on adult readers, many of you asked for something specifically for kids and teens — books that are imaginative, adventurous, beautifully written… and either explicitly Christian or comfortably aligned with a Christian worldview. So in this episode, I build a starter shelf for families, youth leaders, teachers, and young readers themselves.We cover:• Middle Grades (explicitly Christian SFF + Christian-friendly classics)• Young Adult (explicitly Christian + secular works with strong moral foundations)• Stories that emphasize courage, sacrifice, redemption, humility, loyalty, and hopeIf you're building a home library — or just looking for your next great read — this one's for you.
In this week's episode of The Wrap, Chris Whalen analyzes the Blue Owl situation as part of a broader pattern in private credit. He argues that private credit firms purchasing insurance companies is "the fox getting into the hen house" since insurance assets are held at book value rather than marked to market, beyond easy regulator reach. Chris makes the case that public markets are superior due to transparency and liquidity, while private markets mainly benefit Wall Street through higher fees, and predicts roughly half of private equity managers will struggle to raise capital due to poor performance. From his Washington visit, Chris notes redistricting has left few genuinely competitive House seats, discusses a Supreme Court case on Voting Rights Act enforcement, and predicts 2028 will be Rahm Emanuel versus Marco Rubio. He explains Vice Chair Michelle Bowman's proposal to roll back Basel III mortgage restrictions that have discouraged bank housing finance for 15 years. On silver, Chris describes Chinese exchanges imposing trading limits due to supply constraints, commercial buyers sourcing from artisanal mines, and potential COMEX cash settlement, noting he continues adding to gold and silver positions despite volatility.Use the code TheWrap2026 for 25% off your first year of The Institutional Risk Analyst https://www.theinstitutionalriskanalyst.com/plans-pricingLinks: The Institutional Risk Analyst: https://www.theinstitutionalriskanalyst.com/ Inflated book (2nd edition): https://www.barnesandnoble.com/w/inflated-r-christopher-whalen/1146303673Twitter/X: https://twitter.com/rcwhalen Website: https://www.rcwhalen.com/ Timestamps:0:00 Preview: The fox getting into the hen house 0:38 Welcome back — Blue Owl and the private credit blowup 1:23 Chris's reaction to Blue Owl restricting redemptions 3:19 Why this matters for retail investors and retirees 4:21 Two reasons this matters — volatility and annuity risk 5:59 How many people truly understand this risk? 6:47 It's not a headline issue until it becomes one 9:22 The Modigliani-Miller Theorem explained 11:12 Do you dabble in private markets at all? 12:18 How do you see this ultimately playing out? 13:05 Half of all PE managers will go out of business 15:12 Do you get pushback from the industry? 16:06 Moving to DC — upcoming midterms 16:45 The disconnect between media narrative and reality 18:22 Supreme Court case on Voting Rights Act 20:33 Base case for midterms — who takes the House? 22:42 Trump administration's communication problems 23:30 Bold call: Rahm Emanuel for Democratic nomination 2028 24:56 The case for Rahm Emanuel 27:09 Marco Rubio vs Rahm Emanuel prediction 28:23 Michelle Bowman's significant speech on Basel III 30:07 How Basel III distorted the mortgage market for 15 years 32:15 What's going on in silver specifically? 34:55 The silver squeeze — producers going to artisanal mines 36:01 Still long gold and silver, adding positions 37:01 What Chris is watching next week
Fresh off their interview with Mewgenics co-creator Edmund McMillen, the Triple Click gang dives into the game itself. They talk about the gross-out humor, the brilliant combat, and that truly spectacular soundtrack. (All of my nights, I'm chasin' rats!)One More Thing:Kirk: Suno, AI Music, and the Bad Future - Adam Neely, YouTube/NebulaMaddy: Overwatch updateJason: Lost Lambs (Madeline Cash)LINKS:“Eatin' Rats” by Ridiculon from the Mewgenics OST, 2026
Join me as I use my indoor voice to explain the effects of raised voices and how animals from other continents can make an appearance in your town. — Support and sponsor this show! Venmo Tip Jar: @wellthatsinteresting Instagram: @wellthatsinterestingpod Bluesky: @wtipod Threads: @wellthatsinterestingpod Twitter: @wti_pod Listen on YouTube!! Oh, BTW. You're interesting. Email YOUR facts, stories, experiences... Nothing is too big or too small. I'll read it on the show: wellthatsinterestingpod@gmail.com WTI is a part of the Airwave Media podcast network! Visit AirwaveMedia.com to listen and subscribe to other incredible shows. Want to advertise your glorious product on WTI? Email me: wellthatsinterestingpod@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices
Send a textGene regulation through RNAs, the neurobiology of opioid addiction, and how psychedelics affect drug-seeking by modulating inflammation and plasticity. Not medical advice.TOPICS DISCUSSED:Gene regulation basics: DNA transcribes to RNAs, including non-coding types like microRNAs that inhibit mRNA translation into proteins, influencing up to 60% of the proteome.Non-coding RNAs in neuroplasticity: MicroRNAs and circular RNAs regulate synaptic changes, with activity-induced ones like miR-485-5p linked to rapid responses in drug cue memory and addiction reinforcement.Opioid addiction models: Rats self-administer heroin or fentanyl via levers, showing compulsive seeking; fentanyl's higher potency drives faster learning but similar long-term effects to heroin when doses are equated.Differences between opioids: Heroin and fentanyl both activate mu-opioid receptors for euphoria and dopamine release, but fentanyl lingers longer; no major behavioral differences in seeking once potency is matched.Psilocybin's effects on addiction: A single psilocybin dose post-abstinence reduces heroin-seeking in rats by dampening neuroinflammation in brain regions like the nucleus accumbens and prefrontal cortex.Brain Inflammation: Opioids induce pro-inflammatory changes via cytokines like IL-17A and pathways like TNF-alpha, leading to glial activation and blood-brain barrier leaks; psilocybin counters this.MicroRNA biomarkers: Blood microRNAs reflect gene expression patterns tied to disease states, with potential to predict opioid relapse risk, treatment response, or neonatal withdrawal severity non-invasively.Future research: Ongoing work links psilocybin's serotonin 2A activation to anti-inflammatory gene changes, plus human studies on microRNAs for personalized addiction treatments.ABOUT THE GUEST: Stephanie Daws, PhD is an associate professor at Temple University in the Center for Substance Abuse Research and Department of Neurosciences, where she researches mechanisms of drug-seeking behavior with a focus on opioids and psychedelics.RELATED EPISODE:M&M 2 | Psilocybin, LSD, Ketamine, InflamSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts
Time For our favorite Wednesday game "Rats Off A Ship" - Jimmy G possible Dolphins QB in 2026? - Connor McGregor return to MMA - Mark Cuban on Tanking In the NBA
Stupid News Extra 2-18-2026 …Come to the Big Apple and See all the Rats
In this episode, Rachel visits with Dan Gates who is the face of Coloradans for Responsible Wildlife Management. He has been the face of the fight to save the hunt and he and I are both adamant that the ag and outdoors communities must stand shoulder to shoulder against attacks.You can find his podcast Through the Gates wherever you listen. This is my favorite episode- https://podcasts.apple.com/us/podcast/ep-80-know-your-enemy/id1788435333?i=1000743963644This episode is brought to you by the generous support of Adam Rose at Iliff Custom Cabinetry. Find him at www.iliffcustomcabinetry.com or on The Facebook at https://www.facebook.com/icucab/. If you see Adam, please let him know you heard about him here.Check our our cows on the Anywhere Cam site at https://anywhere.cam/. Scroll down to the Hereford cows and tada!
#210 - What if travel wasn't a checklist but a classroom? I sat with Joy Owens—mother of two, CEO and co-owner of Butler Travel, and veteran of 60 countries—to explore how faith, service, and slow travel can shape a family and a life. From a grandmother who's visited more than 80 countries to Joy's first trip at three months old, her story moves through mission work in Zambia and Kenya, a scrappy road journey toward Argentina, and a solo $10-a-day push to Panama that turned from a rat-infested night into radical hospitality.Joy walks us through teaching in Honduras and Taiwan, the culture shock of moving to Alaska, and why she and her husband bought Butler Travel to serve nonprofits and missionaries with complex ticketing and group logistics. She shares a gripping emergency reroute for a family in Tanzania that helped their daughter reach lifesaving care, and she opens up about surrendering control when December bills loomed, only to witness the agency's busiest month on record. For Joy, faith isn't an accessory; it's how she navigates risk, money, parenting, and purpose.We also dig into the messy magic of traveling with little kids: babies on planes during the quiet months of 2020, a six-week Europe adventure with bikes and tents, and the art of choosing your hard when tantrums and missed trains collide. Joy makes the case for slow travel—one hub, deeper days, fewer repacks—and tells unforgettable stories, from crossing open water in foldable kayaks to a budget misadventure on a Greek island complete with a kindly, very unbothered nude local offering fruit and cheese.If you lead mission trips, plan family journeys, or crave meaningful travel that builds resilience and empathy, this conversation is your map. Subscribe, share with a friend who loves adventure, and leave a review to tell us: what trip changed you most?To learn more about Joy check out www.butlertravel.com and use the code JAKE10 to get a 10% discount. You can also follow Joy and Butler Travel on Instagram @butlertravel1.You can follow me and the podcast on Instagram @humanadventurepod and check out my website www.thehumanadventure.net.
Jonathan Graves returns to the show after a few years hiatus. He’s here to tal about the return of The Riddler! Jonathan hosts a Looney Tunes podcast and Frank Gorshin has a bit of a connection there. We dive into this one and discuss the difficulty and clever nature of the riddles used in the show as well as revealing that this was the first Riddler story I saw. Another week, another set of factoids and weird stats that I hope you are enjoying in this retrospective look back at 60’s Batman as it turns 60 years old. Jonathan Graves hosts This Means Podcast which you can find anywhere podcasts are found and follow on social media @thismeanspodcast -Brandon The Brandon Peters Show will return next week as EB Kogan takes on The Mad Hatter! TECHNICAL INFORMATIONVocalsBrandon – Shure SM58-LC (Recorded with Zoom)Jonathan – Unknown Microphone (Recorded with Zoom) Post ProductionNCH Wavepad Masters Edition v8.38NCH MixPad Masters v5.22The Levelator 2 RUNTIME: 59 minutes
Karen realizes shes finally made it, Drita gives her daughter the worst advice possible, and Carla shoe shops to prepare for Joe's prison release!For early releases, and more go to my patreonwww.patreon.com/shorejustine Hosted on Acast. See acast.com/privacy for more information.
There have been rumors circulating around the internet about Bam potentially landing on the Golden State Warriors, as it was reported they might go after him in the offseason. Tobin thinks it might be a great idea despite his and Jimmy's relationship may still be frosty, and Leroy thinks the window has passed. Then we play our favorite Wednesday game Rats Off A Ship!; Dehaun Watson, Valentines Day, and more!
Intro - Mike Welcome back to another episode of Let's Go Hunt, not responsible for accidents, acts of God, or misuse of our product. Tonight! Dave Packard, who is finally unbroken Sam Alexander -ate that bad chicken Vince H, who used to be cool And, Mike Goncalves, satisfied with the waterfowl season Around the Campfire Tonight: From my personal favorite youtube channel, we have Jace Cox from Fabrats Sam's special note: leave us a review if you would like to see the downfall of corporate podcasts! Warheads on Foreheads with Mike https://www.msn.com/en-us/news/world/this-10mm-glock-vs-grizzly-bear-encounter-changed-the-debate-on-defense/ar-AA1KScfy Personal Gear Chat and Updates: Mike Hunting mask thing Dave Went spotlighting a couple nights Fog was thicc Been seeing a few lion hunters Sam New Year's New Shite Vince I got nothing new Tanning the coyote hide Fleshing Setting the fur Bark Liqueur Tanning my Son's deer hide for leather News and World Events Initiative 82 https://leg.colorado.gov/content/wildlife-and-ecosystem-conservation-commission-0 Wyoming Corner Crossing going to the Supreme Court? https://montanafreepress.org/2025/05/22/landowner-looks-to-appeal-loss-in-corner-crossing-case-to-us-supreme-court/ Spotlighting With Dave: Please, if you listen to our show, leave a review! Go to lghpodcast.com -> Click on Support the Show -> Leave a Review! -> Follow the link to your favorite podcast brain beamer and leave us a review! Email contact@lghpodcast.com and get a sticker pack! Support the sport and take a buddy hunting! If you like that buddy, tell them about our show! If you don't like that buddy, trap him in the skunk spray. Hit us up at lghpodcast.com. Thanks for listening and Let's Go Hunt! EMAIL: contact@lghpodcast.com Let's Go Hunt Archives - Firearms Radio Network Gideon Optics affiliate coupon code: MOIST Camorado affiliate code: LETSGOHUNT Five Star Alterations code: MOIST 10% (11%) off!
Mea Culpa welcomes back best-selling author, CNN Senior Legal Analyst, and former federal and state prosecutor Elie Honig. Michael and Elie discuss gun control, the upcoming January 6th trials, and how Bill Barr broke the prosecutor's code and corrupted the Justice Department.
Alexis actually won something at the company lunch -- let's get burritos! A GIANT thank you to listener Stephanie for the coconut cake(s), for Valentine's Day - order McDonald's caviar McNuggets and join the Rat Roster, and the latest on Savannah Guthrie's mom See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Tuck chats with Encanto actor Jess Darrow (they/them) about working with Disney as outspoken queer person, singing the transest possible song for their Encanto audition, being queer-awakened by a certain Disney couple, and declaring pole dancing the most they/them hobby. Listen to the full episode on Patreon to hear how Tuck and Jess met via goofing off on Letterboxd… plus Jess coming into their queerness while making Encanto; their mission to make Captain Hook gay; their big discovery about comedians; their takes on RATS and GREECE; their hot take on cishet relationships; and much more!!! Find Jess at @jessdarrow_ on IG and on IMDb. Find Tuck on book tour in Baltimore on Feb 12: RSVP here. Submit advice questions or AMA prompts via our new form! Senior Producer: Ozzy Llinas Goodman Logo: Ira M. LeighMusic: Breakmaster CylinderAdditional Music: Blue Dot Sessions
Discussion of things literally or figuratively unearthed in the last quarter of 2025 continues. It begins with potpourri then covers tools, Neanderthals, edibles and potables, art, shipwrecks, medical finds, and repatriations. Research: Abdallah, Hanna. “Famous Easter Island statues were created without centralized management.” PLOS. Via EurekAlert. 11/26/2025. https://www.eurekalert.org/news-releases/1106805 Abdallah, Hannah. “Early humans butchered elephants using small tools and made big tools from their bones.” PLOS. Via EurekAlert. 10/8/2025. https://www.eurekalert.org/news-releases/1100481 Abdallah, Hannah. “Researchers uncover clues to mysterious origin of famous Hjortspring boat.” EurekAlert. 10/12/2025. https://www.eurekalert.org/news-releases/1108323 Archaeology Magazine. “Medieval Hoard of Silver and Pearls Discovered in Sweden.” https://archaeology.org/news/2025/10/14/medieval-hoard-of-silver-and-pearls-discovered-in-sweden/ Archaeology Magazine. “Possible Trepanation Tool Unearthed in Poland.” 11/13/2025. https://archaeology.org/news/2025/11/13/possible-trepanation-tool-unearthed-in-poland/ Arkeologerna. “Rare 5,000-year-old dog burial unearthed in Sweden.” 12/15/2025. https://news.cision.com/se/arkeologerna/r/rare-5-000-year-old-dog-burial-unearthed-in-sweden,c4282014 Arnold, Paul. “Ancient ochre crayons from Crimea reveal Neanderthals engaged in symbolic behaviors.” Phys.org. 10/30/2025. https://phys.org/news/2025-10-ancient-ochre-crayons-crimea-reveal.html Arnold, Paul. “Dating a North American rock art tradition that lasted 175 generations.” Phys.org. 11/28/2025. https://phys.org/news/2025-11-dating-north-american-art-tradition.html Bassi, Margherita. “A Single Gene Could Have Contributed to Neanderthals’ Extinction, Study Suggests.” Smithsonian. 10/30/2025. https://www.smithsonianmag.com/smart-news/a-neanderthal-gene-variant-related-to-red-blood-cells-may-have-contributed-to-their-extinction-180987586/ Benjamin Pohl, Chewing over the Norman Conquest: the Bayeux Tapestry as monastic mealtime reading, Historical Research, 2025;, htaf029, https://doi.org/10.1093/hisres/htaf029 Benzine, Vittoria. “Decoded Hieroglyphics Reveal Female Ruler of Ancient Maya City.” ArtNet. 10/27/2025. https://news.artnet.com/art-world/foundation-stone-maya-coba-woman-ruler-2704521 Berdugo, Sophie. “Easter Island statues may have 'walked' thanks to 'pendulum dynamics' and with as few as 15 people, study finds.” LiveScience. 10/19/2025. https://www.livescience.com/archaeology/easter-island-statues-may-have-walked-thanks-to-pendulum-dynamics-and-with-as-few-as-15-people-study-finds Billing, Lotte. “Fingerprint of ancient seafarer found on Scandinavia’s oldest plank boat.” EurekAlert. 10/12/2025. https://www.eurekalert.org/news-releases/1109361 Brhel, John. “Rats played major role in Easter Island’s deforestation, study reveals.” EurekAlert. 11/17/2025. https://www.eurekalert.org/news-releases/1106361 Caldwell, Elizabeth. “9 more individuals unearthed at Oaklawn could be 1921 Tulsa Race Massacre victims.” Tulsa Public Radio. 11/6/2025. https://www.publicradiotulsa.org/local-regional/2025-11-06/9-more-individuals-unearthed-at-oaklawn-could-be-1921-tulsa-race-massacre-victims Clark, Gaby. “Bayeux Tapestry could have been originally designed as mealtime reading for medieval monks.” Phys.org. 12/15/2025. https://phys.org/news/2025-12-bayeux-tapestry-mealtime-medieval-monks.html#google_vignette Cohen, Alina. “Ancient Olive Oil Processing Complex Unearthed in Tunisia.” Artnet. 11/21/2025. https://news.artnet.com/art-world/ancient-olive-oil-complex-tunisia-2717795 Cohen, Alina. “MFA Boston Restores Ownership of Historic Works by Enslaved Artist.” ArtNet. 10/30/2025. https://news.artnet.com/art-world/mfa-boston-david-drake-jars-restitution-2706594 Fergusson, Rachel. “First DNA evidence of Black Death in Edinburgh discovered on teeth of excavated teenage skeleton.” The Scotsman. 11/5/2025. https://www.scotsman.com/news/first-dna-evidence-black-death-edinburgh-discovered-teeth-excavated-teenage-skeleton-5387741 Folorunso, Caleb et al. “MOWAA Archaeology Project: Enhancing Understanding of Benin City’s Historic Urban Development and Heritage through Pre-Construction Archaeology.” Antiquity (2025): 1–10. Web. Griffith University. “Rare stone tool cache tells story of trade and ingenuity.” 12/2/2025. https://news.griffith.edu.au/2025/12/02/rare-stone-tool-cache-tells-story-of-trade-and-ingenuity/ Han, Yu et al. “The late arrival of domestic cats in China via the Silk Road after 3,500 years of human-leopard cat commensalism.” Cell Genomics, Volume 0, Issue 0, 101099. https://www.cell.com/cell-genomics/fulltext/S2666-979X(25)00355-6 Hashemi, Sara. “A Volcanic Eruption in 1345 May Have Triggered a Chain of Events That Brought the Black Death to Europe.” Smithsonian. 12/8/2025. https://www.smithsonianmag.com/smart-news/a-volcanic-eruption-in-1345-may-have-triggered-a-chain-of-events-taht-brought-the-black-death-to-europe-180987803/ Hjortkjær, Simon Thinggaard. “Mysterious signs on Teotihuacan murals may reveal an early form of Uto-Aztecan language.” PhysOrg. 10/6/2025. https://phys.org/news/2025-10-mysterious-teotihuacan-murals-reveal-early.html Institut Pasteur. “Study suggests two unsuspected pathogens struck Napoleon's army during the retreat from Russia in 1812.” Via EurekAlert. 10/24/2025. https://www.eurekalert.org/news-releases/1102613 Jones, Sam. “Shells found in Spain could be among oldest known musical instruments.” The Guardian. 12/2/2025. https://www.theguardian.com/science/2025/dec/02/neolithic-conch-like-shell-spain-catalonia-discovery-musical-instruments Kasal, Krystal. “Pahon Cave provides a look into 5,000 years of surprisingly stable Stone Age tool use.” Phys.org. 12/16/2025. https://phys.org/news/2025-12-pahon-cave-years-stable-stone.html Kristiansen, Nina. “Eight pages bound in furry seal skin may be Norway's oldest book.” Science Norway. 11/3/2025. https://www.sciencenorway.no/cultural-history-culture-history/eight-pages-bound-in-furry-seal-skin-may-be-norways-oldest-book/2571496 Kuta, Sarah. “109-Year-Old Messages in a Bottle Written by Soldiers Heading to Fight in World War I Discovered on Australian Beach.” Smithsonian. 11/6/2025. https://www.smithsonianmag.com/smart-news/109-year-old-messages-in-a-bottle-written-by-soldiers-heading-to-fight-in-world-war-i-discovered-on-australian-beach-180987649/ Kuta, Sarah. “A Storm Battered Western Alaska, Scattering Thousands of Indigenous Artifacts Across the Sand.” Smithsonian. 10/31/2025. https://www.smithsonianmag.com/smart-news/a-storm-battered-western-alaska-scattering-thousands-of-indigenous-artifacts-across-the-sand-180987606/ Kuta, Sarah. “Archaeologists Unearth More Than 100 Projectiles From an Iconic Battlefield in Scotland.” Smithsonian. 11/5/2025. https://www.smithsonianmag.com/smart-news/archaeologists-unearth-more-than-100-projectiles-from-an-iconic-battlefield-in-scotland-180987641/ Kuta, Sarah. “Hundreds of Mysterious Victorian-Era Shoes Are Washing Up on a Beach in Wales. Nobody Knows Where They Came From.” Smithsonian. 1/5/2026. https://www.smithsonianmag.com/smart-news/hundreds-of-mysterious-victorian-era-shoes-are-washing-up-on-a-beach-in-wales-nobody-knows-where-they-came-from-180987943/ Lawson-Tancred, Jo. “Golden ‘Tudor Heart’ Necklace Sheds New Light on Henry VIII’s First Marriage.” Artnet. 10/14/2025. https://news.artnet.com/art-world/tudor-heart-pendant-british-museum-fundraiser-2699544 Lawson-Tancred, Jo. “Long-Overlooked Black Veteran Identified in Rare 19th-Century Portrait.” ArtNet. 10/27/2025. https://news.artnet.com/art-world/black-veteran-thomas-phillips-portrait-identified-2704721 Lipo CP, Hunt TL, Pakarati G, Pingel T, Simmons N, Heard K, et al. (2025) Megalithic statue (moai) production on Rapa Nui (Easter Island, Chile). PLoS One 20(11): e0336251. https://doi.org/10.1371/journal.pone.0336251 Lipo, Carl P. and Terry L. Hunt. “The walking moai hypothesis: Archaeological evidence, experimental validation, and response to critics.” Journal of Archaeological Science. Volume 183, November 2025, 106383. https://www.sciencedirect.com/science/article/abs/pii/S0305440325002328 Lock, Lisa. “Pre-construction archaeology reveals Benin City's historic urban development and heritage.” 10/29/2025. https://phys.org/news/2025-10-pre-archaeology-reveals-benin-city.html#google_vignette Lock, Lisa. “Pre-construction archaeology reveals Benin City's historic urban development and heritage.” Antiquity. Via PhysOrg. 10/29/2025. https://phys.org/news/2025-10-pre-archaeology-reveals-benin-city.html#google_vignette Lynley A. Wallis et al, An exceptional assemblage of archaeological plant fibres from Windmill Way, southeast Cape York Peninsula, Australian Archaeology (2025). DOI: 10.1080/03122417.2025.2574127 Lyon, Devyn. “Oaklawn Cemetery excavation brings investigators closer to identifying Tulsa Race Massacre victims.” Fox 23. 11/6/2025. https://www.fox23.com/news/oaklawn-cemetery-excavation-brings-investigators-closer-to-identifying-tulsa-race-massacre-victims/article_67c3a6b7-2acc-44cb-93ce-3d3d0c288eca.html Marquard, Bryan. “Bob Shumway, last known survivor of the deadly Cocoanut Grove nightclub fire, dies at 101.” 11/12/2025. https://www.bostonglobe.com/2025/11/12/metro/bob-shumway-101-dies-was-last-known-cocoanut-grove-fire-survivor/?event=event12 Marta Osypińska et al, A centurion's monkey? Companion animals for the social elite in an Egyptian port on the fringes of the Roman Empire in the 1st and 2nd c. CE, Journal of Roman Archaeology (2025). DOI: 10.1017/s1047759425100445 Merrington, Andrew. “Extensive dog diversity millennia before modern breeding practices.” University of Exeter. 11/13/2025. https://news.exeter.ac.uk/faculty-of-humanities-arts-and-social-sciences/archaeology-and-history/extensive-dog-diversity-millennia-before-modern-breeding-practices/ Morris, Steven. “Linguists start compiling first ever complete dictionary of ancient Celtic.” The Guardian. 12/8/2025. https://www.theguardian.com/science/2025/dec/08/linguists-start-compiling-first-ever-complete-dictionary-of-ancient-celtic Museum of Fine Arts, Boston. “Museum of Fine Arts, Boston, Resolves Ownership of Works by Enslaved Artist David Drake.” 10/29/2025. https://www.mfa.org/press-release/david-drake-ownership-resolution Narcity. “Niagara has a 107-year-old shipwreck lodged above the Falls and it just moved.” https://www.narcity.com/niagara-falls-shipwreck-iron-scow-moved-closer-to-the-falls Newcomb, Tim. “A 76-Year-Old Man Went On a Hike—and Stumbled Upon a 1,500-Year Old Trap.” Popular Mechanics. 11/21/2025. https://www.popularmechanics.com/science/archaeology/a69441460/reindeer-trap/ Nordin, Gunilla. “Ancient wolves on remote Baltic Sea island reveal link to prehistoric humans.” Stockholm University. Via EurekAlert. 11/24/2025. https://www.eurekalert.org/news-releases/1106807 Oster, Sandee. “DNA confirms modern Bo people are descendants of ancient Hanging Coffin culture.” Phys.org. 12/6/2025. https://phys.org/news/2025-12-dna-modern-bo-people-descendants.html Oster, Sandee. “Rare disease possibly identified in 12th century child's skeletal remains.” PhysOrg. 10/10/2025. https://phys.org/news/2025-10-rare-disease-possibly-12th-century.html Osuh, Chris and Geneva Abdul. “Lost grave of daughter of Black abolitionist Olaudah Equiano found by A-level student.” The Guardian. 11/1/2025. https://www.theguardian.com/uk-news/2025/nov/01/lost-grave-daughter-black-abolitionist-olaudah-equiano-found-by-a-level-student Silvia Albizuri et al, The oldest mule in the western Mediterranean. The case of the Early Iron Age in Hort d'en Grimau (Penedès, Barcelona, Spain), Journal of Archaeological Science: Reports (2026). DOI: 10.1016/j.jasrep.2025.105506 Skok, Phoebe. “Ancient shipwrecks rewrite the story of Iron Age trade.” PhysOrg. 10/14/2025. https://phys.org/news/2025-10-ancient-shipwrecks-rewrite-story-iron.html The History Blog. “600-year-old Joseon ship recovered from seabed.” 11/15/2025. https://www.thehistoryblog.com/archives/74652 The History Blog. “Ancient pleasure barge found off Alexandria coast.” 12/9/2025. https://www.thehistoryblog.com/archives/74860 The History Blog. “Charred Byzantine bread loves stamped with Christian imagery found in Turkey.” 10/13/2025. https://www.thehistoryblog.com/archives/74352 The History Blog. “Early medieval silver treasure found in Stockholm.” 10/12/2025. https://www.thehistoryblog.com/archives/74343 The History Blog. “Roman amphora with sardines found in Switzerland.” 12/15/2025. https://www.thehistoryblog.com/archives/74904 The Straits Times. “Wreck of ancient Malay vessel discovered on Pulau Melaka.” 10/31/2025. https://www.straitstimes.com/asia/se-asia/wreck-of-ancient-malay-vessel-discovered-on-pulau-melaka Thompson, Sarah. “The forgotten daughter: Eliza Monroe Hay’s story revealed in her last letters.” W&M News. 9/30/2025. https://news.wm.edu/2025/09/30/the-forgotten-daughter-eliza-monroes-story-revealed-in-her-last-letters/ Tuhkuri, Jukka. “Why Did Endurance Sink?” Polar Record 61 (2025): e23. Web. https://www.cambridge.org/core/journals/polar-record/article/why-did-endurance-sink/6CC2C2D56087035A94DEB50930B81980 Universitat de Valencia. “The victims of the Pompeii eruption wore heavy wool cloaks and tunics, suggesting different environmental conditions in summer.” 12/3/2025. https://www.uv.es/uvweb/uv-news/en/news/victims-pompeii-eruption-wore-heavy-wool-cloaks-tunics-suggesting-different-environmental-conditions-summer-1285973304159/Novetat.html?id=1286464337848&plantilla=UV_Noticies/Page/TPGDetaillNews University of Glasgow. “Archaeologists recover hundreds of Jacobite projectiles in unexplored area of Culloden.” 10/30/2025. https://www.gla.ac.uk/news/headline_1222736_en.html University of Vienna. “Neanderthal DNA reveals ancient long-distance migrations.” 10/29/2025. https://www.univie.ac.at/en/news/detail/neanderthal-dna-reveals-ancient-long-distance-migrations Zhou, H., Tao, L., Zhao, Y. et al. Exploration of hanging coffin customs and the bo people in China through comparative genomics. Nat Commun 16, 10230 (2025). https://doi.org/10.1038/s41467-025-65264-3 Zinin, Andrew. “Ancient humans mastered fire-making 400,000 years ago, study shows.” Phys.org. 10/10/2025. https://phys.org/news/2025-12-ancient-humans-mastered-years.html See omnystudio.com/listener for privacy information.