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I can't believe I completely failed in this episode to draw attention to the fact that Dr. Chaos is, in fact, a Superman villain. But then again, both games this episode read like latter-day comic book villains: Good-hearted souls with the best of intentions yet who somehow strayed from the straight-and-narrow path and now simply cause pain and suffering (especially among Gen X kids). The ambitions greatly outstrip the execution with this episode, as two attempts to tap into the exploratory action trend that dominated the NES in 1988 utterly fail to provide players with compelling reasons to delve into their worlds. Suffering from grievous design, visual, and technical shortcomings, both Dr. Chaos and Superman rank among the bottom tier of NES games to date despite their creators' obvious and admirably grandiose visions. Production note: NES footage captured from @Analogue Nt Mini. Video upscaled to 720 with XRGB Mini Framemeister. Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more!
This week we have a pair of perfectly tolerable games that seemingly no one remembers. Yes, by late 1988, the NES library had grown sufficiently large that it could contain games beyond "brilliant" and "execrable"—works of competent mediocrity doomed by their lukewarm nature to be relegated to the dustbin of obscurity. Cobra Command takes a mundane auto-scrolling shooter and turns it into a Choplifter-inspired adventure with a touch of exploration and puzzle-solving. A fine start! But utterly relentless in its difficulty level and saddled with some very strange, almost "sticky" controls. It's fine, almost good, but it just misses the mark. Meanwhile, Anticipation offers inclusive thrills (if you are a preppy, 30-something Caucasian) and demands you deduce the nature of premade connect-the-dots puzzles before your competition does. It's fine. It exists, and it rounded out the NES library with more family-friendly board games. But does anyone want to play it today? I can't imagine. Production note: NES footage captured from @Analogue Nt Mini. Video upscaled to 720 with XRGB Mini Framemeister. Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more!
In this episode, I learned that the Power Pad is not really designed for use on hardwood floors. Bring back that deep-pile '70s shag, baby. My feet are killing me. Super Team Games gives us the last of Nintendo's casual-appeal titles for 1988. There's still one final Nintendo-published game for the year, but it's kind of the opposite of casual-appeal—really, the closest Nintendo themselves ever got to "git gud" difficulty on NES. But Super Team Games is meant for small people to pretend to exercise with, or for big people to be uncomfortably intimate with. As for the headline feature, Blades of Steel, it's an even more casual-appeal approach to hockey than Nintendo's Ice Hockey. You don't have to make any meaningful choices in this game besides deciding when to shoot for the goal... and how hard to hammer the punch button during player-versus-player fights. Production note: NES footage captured from @Analogue Nt Mini. Video upscaled to 720 with XRGB Mini Framemeister. Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more!
Remember 1942? That really bad top-down shooter? Capcom would prefer you didn't. And, to wash that bad memory from our collective mind, we have its sequel, 1943: The Battle of Midway, simultaneously a sequel and a heartfelt apology for that previous misstep. Although this arcade adaptation fails to carry over the multiplayer element from the original 1943 coin-op, it makes up for that shortcoming by introducing a permanent skill-upgrade system. One of the better vertical shooters for NES! Meanwhile, Vic Tokai inexplicably publishes Data East's upgraded NES conversion of Bump'N Jump... well, kind of. In Japan, the home port of Bump'N Jump shipped as "Buggy Popper," which suggests it was meant to be a separate game entirely from the arcade game (alias "Burning Rubber"). Anyway, it's super dated. But still kinda fun? Production note: NES footage captured from @Analogue Nt Mini. Arcade footage captured from MiSTer FPGA. Special thanks to @New Wave Toys and @MiSTer Addons . Video upscaled to 720 with XRGB Mini Framemeister. Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more!
Sunsoft gets a major glow-up this episode after a mediocre start as a publisher of ancient arcade ports and one neat-but-meager light gun shooter. No one would accuse them of half-assing it this time around, though; Blaster Master shot instantly to the top of the NES all-time greats list as soon as it debuted, and it still holds up remarkably well despite some unforgiving design choices that make for some incredibly difficult scenarios. The plot may not make much sense, and the weapon degradation system can be deeply demoralizing, but on the whole Blaster Master did a lot to advance the state of the NES art. Also this episode, I take a moment to provide proper context for the whole Tengen thing I erroneously tackled back in the 1987 chronology. Production note: NES footage captured from @Analogue Nt Mini. Video upscaled to 720 with XRGB Mini Framemeister. Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive content, eBooks, and more!
If Super Mario Bros. was the culmination of the Famicom's early history in Japan, Super Mario Bros. 2 for NES served the same role here in the U.S. Debuting as the console hit critical mass in time for its first major holiday season in America, SMB2 sent players into a huge, imaginative game world that they could tackle with their choice of four different characters, not just Mario. Despite its complicated history, SMB2 became one of the system's greatest hits and did a great deal to define Mario in the West. Nintendo took no chances with this one, and this episode also looks at one of the keys to SMB2's staggering success: Nintendo Power magazine. Production note: NES footage captured from @Analogue Nt Mini. Video upscaled to 720 with XRGB Mini Framemeister. Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more!
By a perfectly timed request by patron TheyCallMeSleeper, this episode arrives just in time to be positioned between this channel's coverage of Super Mario Bros. and its American sequel. Of course, this Japan-only sequel has almost nothing to do with that latter game besides the addition of Luigi as the Mario Bro. whose controls and physics turn his adventure into hard mode. But every mode of Super Mario Bros. 2: The Lost Levels amounts to hard mode, doesn't it? Nintendo took no prisoners with this one. No, they took those prisoners and tossed 'em in the wood chipper, laughing cruelly the entire time. Harsh. Production notes: Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more! NES/Famicom footage captured from disk via RGB from @Analogue Nt Mini with Famicom Disk System. Game Boy and Super NES footage captured via RGB from MiSTer FPGA. Video upscaled to 720 with @Retro Tink 5X.
Capcom kicks off one of the most important creative threads of the NES's history: Their collaboration with Disney, back in the days when Disney was simply an animation studio struggling to reinvent itself for a new era rather than an all-consuming media megalith. Ah, but this isn't really a Capcom Disney game, is it? Appearances (and packaging logos) can be deceptive... but the proof is in the gameplay, which is pretty uninspiring in this case. Also this episode: A salvo of classic games from HAL and Nintendo. The former gives us acceptable ports of arcade masterpieces Joust and Millipede, while the latter simply slaps a new wrapper on two Famicom launch ROMs without bothering to tidy up those releases' shortcomings despite the availability of more advanced cartridge tech that could have made for, say, a proper conversion of Donkey Kong. For shame. Production note: NES footage captured from @Analogue Nt Mini. Video upscaled to 720 with @Retro Tink 5X (which accounts for the tearing and distortion in vertically scrolling sequences). Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more!
Continuing the trend of "games converted badly to Famicom in 1986 and published in America two years later," we have Bits Laboratory's disastrous adaptation of Activision's Ghostbusters. A fun, frothy, fast-paced little confection in its original Commodore 64 incarnation, Ghostbusters becomes a miserable and tedious experience on NES, bogged down by monotonous driving sequences and a viciously unfair endgame. You get the impression someone at Bits actually thought they were doing a good deed here and improving the material! And that person should be locked up in a ghost trap, or at least never allowed to touch a computer again. Production note: NES footage captured from @Analogue Nt Mini. Video upscaled to 720 with @Retro Tink 5X (which accounts for the tearing and distortion in vertically scrolling sequences). Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more!
It feels like Famicom is kind of playing catch-up with SG-1000 this episode, as every game appearing here arrived on shelves in the wake of a Sega-published equivalent—either the exact same game (as in Space Invaders), one exploring the same root concept in different ways (Soccer), or a game with almost suspicious conceptual and mechanical similarities (Formation Z). Of course, the Nintendo version of these games absolutely eclipsed Sega's, right? Well... maybe not always. Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more! Production notes: NES and Famicom footage in this episode was captured from an @Analogue Nt Mini via RGB out. Arcade footage (when possible) was captured from MiSTer (special thanks: @MiSTer Addons ). Standard definition video upscaled to 720 with xRGB Mini Framemeister and @Retro Tink 5X.
1985 starts the Famicom on some familiar footing with a couple of future Black Box releases (one great, one meh); two shooters previously seen on SG-1000; and a Commodore 64 conversion from Hudson that would show up on NES under the aegis of its original publisher. No big surprises here (including the apparent Nintendo debut of TOSE, and the fact that the games previously seen on SG-1000 fare a lot better on Famicom), but that won't be the case for long. By the midpoint of 1985, the Famicom library will look wildly different from the NES's as more third parties (and, specifically, more third parties of wildly variable quality) stake their claim on NES. Video Works is funded via Patreon (http://www.patreon.com/gamespite) — support the show and get access to every episode up to two weeks in advance of its YouTube debut! Plus, exclusive podcasts, eBooks, and more! Production note: Footage in this episode was captured from an @Analogue Nt Mini via RGB out. Video upscaled to 720 with xRGB Mini Framemeister and @Retro Tink 5X.
ŚCIĄGNIJ Odc. 7X Tym razem zbieramy się by poczytać kilka wybornych lektur. Jest konkurs i do wygrania kody na film VOD. Zagadki są różnej trudności, ale dla uważnych jest sporo wskazówek, niektóre odpowiedzi były już w poprzednich odcinkach. → Wesprzyj podcast https://archive.org/download/nagralesto-7x-mini-auctores-varii/Nagralesto_7x_mini_AuctoresVarii.mp3 Youtube Spotify Apple RSS ___ Pytania, uwagi, podziękowania, pogróżki – formularz lub e-mail […]
This is a test of the Rode NT Mini Microphone which I just bought on Amazon to up my podcasting game. I have not edited the audio after recording because I don’t have the time. I always look for tools that don’t require me to edit the footage afterwards. I believe this microphone is one such tool. --- Send in a voice message: https://anchor.fm/dereck-tafuma/message
This week JSniperton and Briar Take a look at the Analogue NT Mini Noir, Home Alone, and Much More! Retro Slot is: @JSniperton | @TheBriarRabbit | Find all of the DCP Members on Twitter: @teft |@TheBriarRabbit | @franmirabella | @Mrs5oooWatts | @Holtzmann_YT | @JSniperton | @Arekkz Gaming Art by Ash: @AR_McD Social Media and Twitch Management by Mr_Ar3s: @Mr_Ar3s -------------------------------------------------------- Join us on our DCP LIVE Twitch Channel! https://www.twitch.tv/dcp_live/ Our Patreon is now LIVE! https://www.patreon.com/dcp_live Join our DCP Discord Server! https://discord.gg/dcp -------------------------------------------------------- We have a new merch store! Exclusive t-shirts and more incoming! https://www.dcplivemerch.com Want some sweet DCP tshirts/coffee mugs? https://society6.com/dcp Save 5% on Scuf Gaming with code "DCP" https://scufgaming.com/
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.01.322396v1?rss=1 Authors: Canciani, A., Capitanio, C., Stanga, S., Faravelli, S., Kienlen-Campard, P., Forneris, F. Abstract: Neurotrypsin (NT) is a highly specific nervous system multi-domain serine-protease best known for its selective processing of the potent synaptic organiser agrin. Its enzymatic activity is thought to influence processes of synaptic plasticity, with its deregulation causing accelerated neuromuscular junction (NMJ) degeneration or contributing to forms of mental retardation. Something which, based on the available literature, likely stems from NT-based regulation of agrin signalling. However, dissecting the exact biological implications of NT-agrin interplay is difficult, owing to the scarce molecular detail regarding NT activity and NT-agrin interactions. The difficult recombinant production of NT in its catalytically competent form is at the base of these limitations, and is currently constraining a more detailed molecular, biochemical and structural characterisation of the NT-agrin system. We have developed a novel strategy to reliably produce and purify a truncated but catalytically competent variant of NT called NT-mini. The characterisation of our construct highlighted almost wild type-like behaviour with comparable specificity, and conservation of modulation by calcium and heparin despite the lack of several accessory domains. With the data obtained from NT-mini it was then possible to identify NT's heparin-binding domain, and discover a novel putative Zinc-based modulation of NT. Additionally, NT-mini allowed us to investigate the effect of NT activity on myotube formation in controlled cell-based experiments, evidencing a negative impact on myoblast fusion dependant on enzymatic activity. Collectively, this shows the viability of NT-mini as a model to study NT functionality, allowing to expand both in-vitro and "in-cellulo" investigations and providing a foundation to unravel the molecular underpinnings and biological significance of NT-agrin interactions. Copy rights belong to original authors. Visit the link for more info
Jim is out for his Mom's 90th birthday, so Craig Hewitt from Podcast Motor and Castos sits in the char joining us from France. As he is on vacation (and all the other mics are sold out) he bought a Rode NT Mini, and (beyond his control) was in a room that was high ceiling and hard surfaces (so Dave has run this through a deverb, knowing it somewhat is too aggressive on Dave's voice, but not too much on Craig (I should've witch the Rodecaster to give me separate channels when I hear his room noise. Ready to Start Your Podcast? Check out the School of podcasting and avoid the common podcast mistakes. See www.schoolofpodcasting.com/start TOPICS: 00:00:21 Special Guest Host Craig Hewitt 00:01:22 Sponsor: podcastbranding.co Need a logo? Need Artwork? Listen today to hear what is the difference. The good news is Mark at podcastbranding.co can provide you with either based on 30 years of graphic design. 03:35 Craig's NT Mini 05:51 Zoom Podtrack P4 is Coming 09:18 How Long Should Your Intro Be? 13:20 Research Your Podcast Name Before Using It 17:48 Why Streamyard? 19:05 The History of Castos and Podcast Motor 22:55 Apple Podcast Has Delays in Updating 24:17 Amazon/Audible is Adding Podcasting 26:50 Google Play Music is Dead - Google Podcasts is Alive 27:43 Become and Awesome Supporter 30:54 Indiedropin.com 32:08 Rogue Co-host 36:43 Kicked Off of Anchor For No Reason 39:20 Spotify Hates Music Podcasts 45:08 Podcast Advertising Works 47:44 Craig's Podcast Audience
Welcome to the one and only Coronasphere, you're one stop shop for everything in the video game industry affected by COVID-19! Just kidding, but seriously, it's impacting a LOT!!! This week we bring you the best gaming content, such as dad jokes, Alex Jones, Speedy Gonzales, and Viva La Bam! But there's still plenty of game stuff to talk about, like that one dude from FaZe who shot a gun live on stream and got BANNED! Also, there's a ridiculous $500 NT Mini to play NES games. Why does it cost so much? It's made out of metal! As usual, here are all the links you need in life: Check out our website at litgamingarena.com Join our Discord community! chat.litgamingarena.com We're also on Twitter! www.twitter.com/litgamingarena AND we are on Instagram! @litgamingarena And of course Facebook www.facebook.com/litgamingarenaCO Sound effects obtained from www.zapsplat.com Give our Podchaser list a BIG heart! https://www.podchaser.com/lists/Alternate-Reality-Radio-107Zzr3Wr5 And find our friends here: www.gamingpodcastalliance.com www.missingrollplayerfound.com
The Analogue Nt Mini is returning, Dead or Alive 6 hair rental DLC, the NES creator speaks about the console's strange design, a gamer bed for sale, DOOM deep-dive discussion, and more! Check out our sponsors: Nord VPN - Save 81% on internet privacy & protection
Roundup #44 feat a Switch discussion with Scott, new OSSC, NeoSD overview, NT Mini updates & more!
Roundup #42 feat NT Mini updates, NGP romcart sale, RGB talk w/Nick from HDRetrovision & more!
Roundup #43 feat NT Mini updates, GameHistoryOrg launch, unreleased SNES game & more!
НДД -*- Cracked by..: WAREZ 1999 :.. -*- ДДН ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ Description:.. An episode of the Idle Thumbs podcast in which the guys pretend to be on a different podcast called Press Start Go, but really it's just another Idle Thumbs. Chris and Nick go deep on Into The Breach, which sounds like it's destroying their lives, and Jake talks about some edutainment game. EnJoY EvErYoNe! Do not upload this on inferior boards! ..: ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ ³ Discussed: Into the Breach, Sea of Thieves, Warez 1999, Idle Thumbs GDC 2018 Community Meetup, Nt Mini vintage console reconstruction, Super Nt vintage console reconstruction, Dr. Mario, David Lynch Teaches Typing, Nest, Subnautica
In Ep 101 of the IMPLANTgames Podcast I talk about the Nt mini, RetroUSB AVS, PowerBase Mini FM, dbGrafx Booster TTP, Cheap Games & More! patreon.com/implantgames
In Ep 100 of the IMPLANTgames Podcast I talk about the Analogue Nt mini, PS4 Slim, Darksoft & More! patreon.com/implantgames