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Dr. Robert Brooks is not only a professor at Harvard Medical School, but is one of the world's leading experts on the topic of resilience. In this episode, we get to listen to and learn from Bob, as he asked us to call him, on this crucial topic for kids today! He has so much wisdom and offers so much help in terms of how we help the kids we love learn that they can do hard things. We can't wait for you to listen in on this important episode. And would love to hear any of your favorite takeaways in the comments! . . . . . Owen Learns He Has What it Takes: A Lesson in Resilience Lucy Learns to Be Brave: A Lesson in Courage Grab your tickets today for the Raising Capable Kids Conference with David Thomas, Sissy Goff and special guests! Sign up to receive the monthly newsletter to keep up to date with where David and Sissy are speaking, where they are taco'ing, PLUS conversation starters for you and your family to share! Connect with David, Sissy, and Melissa at raisingboysandgirls.com . . . . . If you would like to partner with Raising Boys and Girls as a podcast sponsor, fill out our Advertise with us form. A special thank you to our sponsors: WAYFAIR: Shop a huge selection of outdoor furniture online. This summer, get outside with Wayfair. Head to Wayfair.com right now. EVERYDAY DOSE: Get 45% off your first subscription order of 30-servings of Coffee+ or Bold+. You'll also receive a starter kit with over $100 in free gifts including a rechargeable frother and gunmetal serving spoon by going to everydaydose.com/RGB or entering RGB at checkout. You'll also get FREE gifts throughout the year! Learn more about your ad choices. Visit megaphone.fm/adchoices
Denuvo DRM strikes again! Locked out of DOOM: TGA for 24-hours, fan curves for LACT, CPU stress testing with OOTC, SteamOS compatibility ratings, and giving up on blinky RGB.
Ancora ebbri del tutto esaurito al BitCare Forum 2025 commentiamo il nuovo ruolo del Lightning Network, oggi visto come protocollo fondamentale per consentire ad altri sotto network della galassia Bitcoin di interoperare.Inoltre: nuovi sviluppi sul caso OP_RETURN, Revolut annuncia una collaborazione con Lightspark per portare bitcoin sulla loro everything app, la BIS fotografa l'andamento dell'adozione di bitcoin, e ci sono nuovi sviluppi dal processo contro Samourai Wallet.It's showtime!
Okay, podcast friends…get ready to have your hearts melted because we have the most adorable podcast guest on Raising Boys and Girls today: Henry Weber! Henry is Sissy's 6 year old nephew who shares lots of his thoughts on what's helped him learn to be more resilient and courageous. We share our favorite tricks on helping the kids we love discover both how resilient and brave they truly are! Lucy Learns to Be Brave: A Lesson in Courage Owen Learns He Has What it Takes: A Lesson in Resilience The Worry-Free Parent . . . . . Grab your tickets today for the Raising Capable Kids Conference with David Thomas, Sissy Goff and special guests! Sign up to receive the monthly newsletter to keep up to date with where David and Sissy are speaking, where they are taco'ing, PLUS conversation starters for you and your family to share! Go behind the scenes and watch our podcast on YouTube! Download a copy of the Raising Boys and Girls Feelings Chart. Connect with David, Sissy, and Melissa at raisingboysandgirls.com. . . . . . If you would like to partner with Raising Boys and Girls as a podcast sponsor, fill out our Advertise with us form. A special thank you to our sponsors: Wayfair: This summer, get outside with Wayfair. Head to Wayfair.com right now. EverydayDose: Everydaydose: Get 45% off your first subscription order of 30-servings of Coffee+ or Bold+ You'll also receive a starter kit with over $100 in free gifts including a rechargeable frother and gunmetal serving spoon by going to everydaydose.com/RGB or entering RGB at checkout. You'll also get FREE gifts throughout the year! KiwiCo: Get $15 off on your Summer Adventure Series at https://tinyurl.com/RBGKiwiCo. Learn more about your ad choices. Visit megaphone.fm/adchoices
At the Tuscany Lightning Summit 2025, we discussed Ark and VTXOs, batching, RGB, DLCs, what constitutes spam on Bitcoin, Bitcoin payments market, miniscript, bitcoin inheritance tools and more.Timestamps:(00:00) - Intro(01:48) - Tiero(09:17) - Alekos Filini(18:40) - Sponsors(20:56) - Anant Tapadia (33:16) - Andi Pitt(44:24) - Sponsors(45:21) - Giacomo ZuccoLinks: https://x.com/tierotiero https://x.com/ArkLabsHQ https://x.com/giacomozucco https://x.com/planb_network https://x.com/1andipitt https://x.com/egodeathcapital https://x.com/anant_tap https://x.com/bitcoinKeeper_ https://x.com/afilini https://x.com/TwentyTwoHW Sponsors:Bold BitcoinCoinKite.com (code LIVERA)Lana by GaloyStephan Livera links:Follow me on X: @stephanliveraSubscribe to the podcastSubscribe to Substack
Here's the Supporter-only Q&A from May 8th, 2025. All comments and questions are fielded through the supporter service Q&A page. Please consider supporting this channel via monthly support services, tips, or even just by using our affiliate links to purchase things you were already going to buy anyway, at no extra cost to you: https://www.retrorgb.com/support.htmlT-Shirts: https://retrorgb.link/tshirtsAmazon Recommended List: http://retrorgb.link/amazonTIMESTAMPS (please assume all links are affiliate / paid links that pay RetroRGB a commission on each sale. Even if links are currently not affiliate, I may update them with one, should a partner list that item for sale in the future):00:00 Welcome!00:07 3D printed designs for MD2 on SCD1?02:06 Which MiSTer Output Connector to use?04:57 PSU's Better Than Triad?: https://www.retrorgb.com/triad.html07:12 Using HD Retrovision cables as BNC / Lumacode: https://amzn.to/3GGESwZ11:16 RGB modding a CRT instead of converting to composite13:30 Is AI affecting RetroRGB?18:27 Bucket list review items?23:01 Safe to put a NAS close to a big CRT?24:55 4K120 HDMI switch / Composite to RGB converter29:28 Thank you!: https://www.retrorgb.com/support.html
Rgb gives you the rundown on current ppp roster and some expectations for the guys as the season progress. This weekend round brought to you by Back9 Botanicals use promo code TPuff10 to save !!! www.back9botanicals.com
Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Daar komt ie om de hoek zeilen, de vrijdag. De dag dat je weet dat in de avond het weekend begint. En dat je die kunt inluiden met een nieuwe aflevering van Einde van de Week Live. Hoe mooi kan het leven soms zijn. In deze editie zitten Huey, Jelle en JJ in de zwoele warmte van de studio en kwebbelen vrolijk over het nieuws van de afgelopen week. Wat is er allemaal gebeurd en welke topics zijn de moeite van het bespreken waard? In deze aflevering hebben de drie het onder andere over natuurlijk het uitstel van GTA 6, de prijsverhoging van de Xbox, de nieuwe IP's van Larian Studio's, de mogelijk komst van Max Payne Remastered en de nieuwe rol van Astrobot bij PlayStation. Deze onderwerpen en meer zie en hoor voorbijkomen in de EvdWL van vrijdag 2 mei.GTA 6 uitgesteld naar 26 mei 2026In ander nieuws kijken de drie ook naar een aantal opvallende trailers, hebben ze slecht nieuws voor de fans van rally-games en zien ze wat opvallends bij het succesverhaal dat Clair Obscur: Expedition 33 heet.Check de brute kracht van de MSI Vector 16 HX AI met een RTX 5080 aan boordDeze week staat de Vector 16 HX AI in de spotlights. Met aan boord een Intel Core Ultra 9 HX processor, de nieuwe RTX 5080 videokaart, een 1TB SSD, een 240Hz QHD+ Scherm, de CoPilot+ functie en een 24-zone RGB toetsenbord. Dit beest van een laptop is nu hier fijn geprijsd bij Alternate.Je hebt keyboards en de Apex Pro TKL van SteelSeriesOf je het nu leuk vindt of niet, voor echt snel gamen op een PC heb je een keyboard nodig. En die zijn er genoeg op de markt. Maar net als bij de headsets weet SteelSeries ook hier de standaard mede neer te zetten. Bijvoorbeeld bij hun funky Apex Pro TKL. Als we hun website mogen geloven het snelste toetsenbord ter wereld. En strak wit met discolichtjes en stille toetsen. Wat wil je nog meer... Hier kun je alle info over het keyboard vinden en/of hem aanschaffen.
Alienware has officially launched its most powerful and design-forward gaming laptops to date, the new Alienware Area-51 series. First announced at CES 2025, the Area-51 laptops mark a return of the brand's most iconic platform, reimagined with next-generation technology and a striking new design language inspired by extraterrestrial phenomena. Available in 16- and 18-inch models, the Area-51 laptops are built to deliver maximum performance and innovation for gamers and creators alike. Equipped with up to an NVIDIA GeForce RTX 5090 Laptop GPU and an Intel Core Ultra 9 275HX CPU, the laptops offer a total performance package of up to 280W, making them the most powerful laptops Alienware has ever produced. A completely reengineered Cryo-tech thermal architecture enables up to 37% more airflow while being 15% quieter than previous models, ensuring high performance without compromise. The new design, dubbed AW30, draws inspiration from the Aurora Borealis, bringing a serene, ethereal aesthetic to the Alienware lineup. A Liquid Teal finish with colour-shifting iridescence, translucent rear thermal shelf with gradient AlienFX lighting, and a Clear Gorilla Glass panel on the underside offer both form and function. These elements combine to deliver an immersive visual experience that mirrors the laptops' gaming capabilities. Additional features include RGB fans, a zero-hinge design for cleaner lines, and support for the latest Gen 5 SSDs with up to 12TB of storage and Microsoft DirectStorage for faster load times. The Alienware Area-51 18 and 16 laptops with RTX 5080 GPUs are now available for purchase on Dell Technologies Ireland website, starting at €4,098.99 and €4,298.99, respectively. Configurations with RTX 5090 and 5070 Ti GPUs will be available soon. With this launch, Alienware reaffirms its commitment to pushing the boundaries of gaming performance and design, offering Irish gamers and tech enthusiasts an experience into the future of high-end computing. More about Irish Tech News Irish Tech News are Ireland's No. 1 Online Tech Publication and often Ireland's No.1 Tech Podcast too. You can find hundreds of fantastic previous episodes and subscribe using whatever platform you like via our Anchor.fm page here: https://anchor.fm/irish-tech-news If you'd like to be featured in an upcoming Podcast email us at Simon@IrishTechNews.ie now to discuss. Irish Tech News have a range of services available to help promote your business. Why not drop us a line at Info@IrishTechNews.ie now to find out more about how we can help you reach our audience. You can also find and follow us on Twitter, LinkedIn, Facebook, Instagram, TikTok and Snapchat.
Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Het. Is. Vrijdag. Een week in april 2025 zit er voor ons en jullie op. Tijd om al het nieuws van de afgelopen zeven dagen samen te vatten en nog eens met je door te nemen. Dit doen we uiteraard in een verse episode van Einde van de Week Live. Eentje die eerder vandaag, zoals elke keer, op Twitch en YouTube gestreamd is. Maar, omdat we weten dat velen van jullie de stream niet kunnen kijken vanwege werk of studie of omdat jullie het graag relaxed terug luisteren, zetten we de video en podcast aan het eind van de dag netjes online. In deze aflevering gaan Jelle, JJ en Koos het hebben over de trailer van Ghost of Yotei, het bizarre succes van Clair Obscure: Expedition 33, de voortgang van Baldur's Gate 3 en onze eerste stappen in Oblivion Remastered. Dit is de EvdWL van vrijdag 25 april.Onze eerste stappen in Oblivion RemasteredIn ander nieuws kijken de drie onder meer naar de tekorten die bij launch dreigen te ontstaan voor de Switch 2, een game die een mode heeft gekregen die bijna ondoenlijk is en de ontwikkelingen rond de Fallout 3 remaster.Check de brute kracht van de MSI Vector 16 HX AI met een RTX 5080 aan boordDeze week staat de Vector 16 HX AI in de spotlights. Met aan boord een Intel Core Ultra 9 HX processor, de nieuwe RTX 5080 videokaart, een 1TB SSD, een 240Hz QHD+ Scherm, de CoPilot+ functie en een 24-zone RGB toetsenbord. Dit beest van een laptop is nu hier fijn geprijsd bij Alternate: https://msi.gm/SC6D9DDD .LG UltraGear's beuker van een monitor: de 5K2KLG UltraGear kwam ons onlangs verblijden met hun nieuwe paradepaardje, wereld's allereerste 5K2K monitor. Daan test hem as we speak en komt komende week met een video daarover. De 5K2K is een regelrechte beuker van een monitor. Check de stats van deze fikse knaap maar eens. Die vind je hier. Een pre-order kun je daar eventueel ook plaatsen: https://tinyurl.com/5csnv95v .Timestamps:00:02:15 Huishoudelijke mededeling: MSI00:05:00 Hoe gaat het met onze trektocht door de provincie Cyrodill?00:15:04 Claire Obscure 30 man, deels Ubisoft, 50 dollar 00:23:45 Ghost of Yotei 00:48:16 BULLETTIME 5K2K monitor00:53:53 GTA 6 trailer
Rgb brings you a solo episode to recap the Fore20 weekend some of local events and also discusses what's ahead for the ppp this season
Rgb is joined by Anthony owner of Greedy Golf to discuss his brand. We start off with little post masters conversation and his journey into golf and how it led to Greedy Golf. He currently just dropped a line of hats with polos and hoodies expected soon!! #518 #bogey #golf #podcast #bogeygolf #explore #fairway #golfer #golfputt #interview #getgreedy #greedy #golftips
The healium Collective is back owners Evan and Lukas join Rgb to talk about their latest drop and where you can find it!! Most listeners know I'm huge fan of their award winning #cowboylemonade trust me the #dna doesn't disappoint
Rgb and Mikey are joined by Upstate Golf Guys Florida Mike and Anthony to break down the home stretch of the Masters we give our onsite as the round progresses into the playoff.
Het is maandag en na een zonnig weekend zijn we volledig opgeladen om de nieuwe werkweek in te gaan. We gaan zoals altijd een lekker zwik content voor jullie produceren, te beginnen met een nieuwe editie van Brievenmaandag. De rubriek waarin we de meest dringende vragen van de community beantwoorden. Boris, Jelle en JJ zitten klaar, taak- en plichtsbewust als ze zijn. Ook deze week heeft de virtuele brievenbus flink geklepperd en dus zijn de drie er eens goed voor gaan zitten. Vragen die ze gaan beantwoorden, draaien onder andere om de karakters van Borderlands 4, betaalbare handhelds en het einde van de Switch. Dit is de Brievenmaandag van maandag 14 april 2025.Keren er karakters vorige Borderlands terug in Borderlands 4?Een van de leden van onze community wil graag een handheld gaan kopen zodat hij af en toe een uurtje daarop kan gamen als hij zijn PS5 Pro niet in de buurt heeft. Maar een Steam Deck is hem te duur. Hebben wij of de community nog een aantal tips voor hen? En gaan we nog een top 5 all time beste games op de Switch maken nu deze console op haar laatste beentjes loopt? Of gaat ie nog wel even mee? De drie heren buigen zich over deze vragen en komen met een potentiële oplossing.Van welke games worden we lekker rustig?Er is ook een vraag over de prijs van digitale games. Waarom is die nog steeds hoger dan de prijs van een fysieke game? Wanneer gaat dat veranderen zeker nu de tarieven-oorlog alles op scherp zet als het gaat om het transport van goederen? Plus, welke games spelen we als we ons rustig willen maken? Hebben we go-to titels voor die situatie of spelen we dan juist helemaal geen games? Over al deze zaken en meer gaan de drie heren het hebben in deze editie van Brievenmaandag.Pak maar liefst 250 euro korting op de MSI Sword 16 HX gaming laptopDeze week zet MSI de Sword 16 HX in de spotlights. Een gaming laptop met onder de motorkap een 14e generatie i7 HX processor, een NVIDIA RTX 4070 videokaart, een 512GB SSD, een 16” full Hd paneel en, het allerbelangrijkste, een 24-zone RGB toetsenbord. Dit fijne stuk hardware kun je nu bij MeGekko met maar liefst 250 euro korting aanschaffen: https://msi.gm/S543FEFA
Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Er staat een warme zaterdag voor de deur en daar gaan we voor. Misschien in ons t-shirt een biertje pakken op het terras of strand. Hoe mooi kan het leven soms zijn. Dat opgeruimde levensgevoel komt je ook tegemoet tijdens deze editie van Einde van de Week Live. De wekelijkse talkshow waarin we de games- en nerd gerelateerde ontwikkelingen van de afgelopen zeven dagen doornemen. Met dit keer Daan, Jelle en Koos achter de desk. Ze hebben het in deze video onder andere over het record aan awards voor Astro Bot, PlayStation dat de zoveelste versie van The last of Us in de schappen legt en de bakken geld die Star Citizen inmiddels heeft binnengehaald. Maar voor wat eigenlijk? Je ziet en hoort het allemaal in de Einde van de Week Live van vrijdag 11 april 2025.PlayStation gooit er nog een The Last of Us versie uitIn deze editie van EvdWL wordt ook gediscussieerd over een aantal nieuwe trailers van games die de komende tijd uitkomen, de releasedatum van Mafia: The Old Country, een spin-off van Rainbow Six, het succes van A Minecraft Movie en de overstap van gamers van Overwatch 2 naar Marvel Rivals.Pak maar liefst 250 euro korting op de MSI Sword 16 HX gaming laptopDeze week zet MSI de Sword 16 HX in de spotlights. Een gaming laptop met onder de motorkap een 14e generatie i7 HX processor, een NVIDIA RTX 4070 videokaart, een 512GB SSD, een 16” full Hd paneel en, het allerbelangrijkste, een 24-zone RGB toetsenbord. Dit fijne stuk hardware kun je nu bij MeGekko met maar liefst 250 euro korting aanschaffen: https://msi.gm/S543FEFACheck de brute kracht & uitstraling van de 5K2K LG Ultragear monitorVandaag kwam LG UltraGear ons verblijden met hun nieuwe paradepaardje, de 5K2K monitor. Een beuker van een monitor die we de komende dagen mogen testen. Mocht je de meer info over deze fikse knaap willen hebben, dan vind je hier alle info die je nodig hebt. Een pre-order plaatsen kan daar ook: https://tinyurl.com/5csnv95vTimestamps:00:00:00 Intro00:00:35 Huishoudelijke mededeling: MSI00:03:00 Wat hebben we de afgelopen week gespeeld?00:08:47 We beginnen deze editie van EvdWL vrolijk… of is dit eigenlijk juist om te huilen. Hier is The Last of Us complete edition.00:16:56 Nerdy nieuwtje, ondanks tientallen miljoen dollars aan budget is de Tomb Raider serie bij Amazon kaput. Ze slagen er niet in een script te maken.00:23:04 Speciaal voor Jelle: Astro Bot won de meeste awards tijdens de afgelopen BAFTA's. De game is nu meer bekroond dan vrijwel alle andere games ooit. Zelfs een Red Dead Redemption 2 komt niet in de buurt.00:27:04 PlayStation heeft weer geanimeerde achtergronden mogelijk gemaakt voor de PS5.00:39:51 Star Citizen heeft nu 800 miljoen dollar binnen gehaald.00:49:00 Unboxing van de LG 45GX950 OLED gaming monitor.00:59:02 Seizoen twee van The Last of Us is nog niet eens begonnen en HBO heeft al seizoen 3 besteld.01:07:57 De launchdatum van de nieuwe Mafia game lijkt gelekt. Het zou 8 augustus zijn.01:17:29 Hoeveel zin hebben we in de volgende games?01:45:17 YouTuber en Nintendo fan ChickenDog is van plan twee maanden voor de Nintendo Store in New York te liggen zodat ie als eerste de Switch 2 kan kopen.
Rgb and Jr jump on for quick chop up with some masters predictions
Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Er staat een fijn weekend voor je klaar. Een die we vast allemaal prima kunnen gebruiken bijvoorbeeld om al het nieuws rond de Switch 2 reveal van Nintendo te verwerken. Want wat is er veel met ons gedeeld en wat hadden we er allemaal een mening over. Geen uniforme mening zoals vaak het geval is bij aankondigingen van Nintendo (vet!), maar veel kritische geluiden en soms zelfs openlijke twisten op social media. Logisch dus dat de drie aanraden, Huey, Jelle en JJ de discussie voortzetten in deze editie van Einde van de Week Vrijdag Live. Er valt namelijk nog meer dan genoeg te bespreken. Natuurlijk wordt het andere nieuws niet vergeten. Dit is de Einde van de Week Live van vrijdag 4 april 2025.De Switch 2 hield de gemoederen de afgelopen dagen flink bezigIn deze editie van EvdWL veel gekwebbel over de Switch 2. De drie hebben het echter ook over de battle royale mode van Battlefield 6, de meest invloedrijke game ooit en Only Fans en AI.Pak ruim 400 euro korting bij aankoop van de MSI Katana 15 AI gaming laptopDeze week zet MSI de Katana A15 AI in de spotlighs. Je kunt maar liefst 400 euro korting scoren bij de aanschaf van een gaming laptop met aan boord de AMD Ryzen 7 processor, een RTX 4060 videokaart, een 1TB SSD, een 15'6” Full HD 144HZ IPS scherm en het 4-zone RGB toetsenbord. Hier vind je de stats en de link naar de korting bij CoolBlue: https://msi.gm/S7CBD620LG Ultragear presenteert ‘s werelds snelste 27” 480 Hz QHD monitorZoals je weet zijn er een hoop presentatoren bij Gamekings erg happy met LG schermen en monitoren. Meerdere van ons hebben hun hardware thuis staan. Jelle sinds kort ook. En wel de LG Ultragear 27” OLED 480 Hz QHD gaming monitor. In deze video kun je de unboxing, installatie en kalibratie van deze forse knaap bekijken. Wil je meer info over de LG Ultragear 27” OLED 480 Hz QHD gaming monitor, dan is hier de pagina met alle ins en outs: https://www.lg.com/nl/monitoren/ultragear-gaming-monitoren/27gx790a-b/Check de Fayzo headset van Trust: comfort voor een zeer betaalbare prijsOp zoek naar een fijne, comfortabele, maar ook betaalbare headset voor jezelf of voor je kids? Check dan de Fayzo Wireless headset van Trust Gaming eens. Met oorkussens die ook op Daan en JJ's grote hoofden passen, een verstelbare hoofdband en draaibare oorschelpen zitten ze prima. Er is draadloze connectie tegelijk met pc/console en telefoon, virtueel 7.1 surround-geluid en je kunt kiezen uit de kleuren wit, zwart en paars krijgen. Verkrijgbaar voor slechts 57 euro. Interesse? Hier vind je alle info en kun je de Fayzo aanschaffen: https://tinyurl.com/yeywk8f6Timestamps:00:00:00 Intro00:02:33 Huishoudelijke mededeling: MSI00:05:25 We gaan naar Kevin, Switch 2 gepreorderd00:20:11 Switch 2 reveal Nintendo Direct, wat vonden jullie er van00:52:39 Donkey Kong game00:54:54 De crowd00:56:06 BULLETTÎME: Trust Gaming00:59:36 Assassin's Creed Shadows Famitsu01:09:58 Battlefield 6 Battle Royale komt eraan01:10:49 Vinted01:17:38 Meest invloedrijke game aller tijden01:19:13 Nog een keer The Last of Us01:20:00 BULLETTÎME: LG Ultragear01:23:48 Only Fans AI01:29:52 Cool & Serious Uncool
Introduction Misaligned AI systems, which have a tendency to use their capabilities in ways that conflict with the intentions of both developers and users, could cause significant societal harm. Identifying them is seen as increasingly important to inform development and deployment decisions and design mitigation measures. There are concerns, however, that this will prove challenging. For example, misaligned AIs may only reveal harmful behaviors in rare circumstances, or perceive detection attempts as threatening and deploy countermeasures – including deception and sandbagging – to evade them. For these reasons, developing a range of efforts to detect misaligned behavior, including power-seeking, deception, and sandbagging, among other capabilities, have been proposed. One important indicator, though, has been hiding in plain sight for years. In this post, we identify an underappreciated method that may be both necessary and sufficient to identify misaligned AIs: whether or not they've turned red, i.e. gone rouge. In [...] ---Outline:(01:43) Historical Evidence for Rouge AI(02:59) Recent Empirical Work(05:18) Potential Countermeasure(05:22) The EYES Eval(06:27) EYES Eval Demonstration(07:40) Future Research Directions(08:42) Conclusion--- First published: April 1st, 2025 Source: https://forum.effectivealtruism.org/posts/uKKoj9iqj2cWKsjrt/mitigating-risks-from-rouge-ai --- Narrated by TYPE III AUDIO. ---Images from the article:Apple Podcasts and Spotify do not show images in the episode description. Try Pocket Casts, or another podcast app.
Rgb and Mikey have some insider knowledge of opening day and plans for renovations of the clubhouse. The boys chop it up about previous round last week and upcoming events for 2025!! #518 #bogey #golf #podcast #bogeygolf #explore #fairway #golfer #golfputt #interview
On this week's show we look at where some Americans are spending nearly $100 a month on streaming services. We also look at some new tech from Sony that promises big improvements for LED TVs. All that plus your emails and the week's news on this episode of the HDTV and Home Theater Podcast. News: Apple TV+, Jason Sudeikis confirm fourth season of ‘Ted Lasso' Lawsuits Hit TCL & Hisense: Are Their QLED TVs A Total Scam? Sony Launches Its First New 4K Blu-ray Player In Over Five Years Other: Spectrum is finally offering a streaming-only subscription for Dodgers Many Americans Spend Over $100 per Month on Subscription Services A recent survey by Bango reveals that nearly 25% of Americans spend over $100 per month on subscription services, including streaming platforms and retail memberships like Amazon Prime. This trend marks a shift from the perception of subscriptions as cost-effective alternatives to traditional cable and satellite services, as consumers face rising costs—streaming plans alone have increased by over 20% in the past two years. To manage expenses, many consumers are turning to subscription bundles, with the average American holding 5.4 subscriptions, including 2 that come through bundled packages. A significant portion of these bundles is linked to mobile phone plans, with 55% of subscribers benefiting from such arrangements. Additionally, 44% of users report receiving services for free through bundles that they previously paid for. Convenience is another critical factor driving consumers toward bundles, as 41% express frustration with managing multiple subscriptions across different apps. A strong demand exists for unified platforms, with 63% of subscribers seeking more options like Verizon's +play. Sony Develops Next-Generation Display System Full Press Release Sony has developed a next-generation display system featuring a high-density LED backlight with independent drive RGB (red, green, and blue) control, designed for large screens. This innovative technology allows each RGB color to emit light independently, resulting in high color purity and the ability to reproduce a vibrant, wide color gamut. Key features of this display system include: Wide Color Gamut Performance: The system covers over 99% of the DCI-P3 color space and about 90% of the ITU-R BT.2020 standard, ensuring enhanced color reproduction. Advanced Backlight Control Technology: Sony's proprietary technology allows for precise control of light gradation, enabling subtle hues and detailed shading across the entire brightness range. This is particularly beneficial for cinematic productions, where accurate color representation is crucial for conveying narrative expression. Accurate Color Reproduction by a Dedicated Control Processor By individually controlling the brightness of the densely packed RGB LEDs, it is possible to render bright areas vividly without white clipping and to delicately depict the nuances of light in dark areas without black crushing. Additionally, the display system is equipped with approximately twice the processing power and pixel correction technology compared to conventional local dimming processing, allowing the reproduction of subtle color differences and accurate colors without color shifts. The display system aims to enhance film production and home viewing experiences, aligning with Sony's commitment to supporting creators through professional-grade monitors used for color grading and reference. Mass production of this new display system is set to begin in 2025, with plans for integration into consumer televisions and displays for content creation.
Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Er staat ons een prettig lenteweekend te wachten. Hoe fijn zou dat wel niet zijn. Even ergens op een terras een kopje koffie drinken of een biertje pakken. Dit vooruitzicht gaan we nog verder opleuken met een nieuwe aflevering van Einde van de Week Vrijdag Live. De talkshow waarin we elke week het belangrijkste game gerelateerde nieuws van de afgelopen zeven dagen met elkaar én de kijkers doornemen. Jelle, Koos en Shelly zit klaar om te kletsen over Topics onder andere de leukste trailers van de Future Gaming Show, het nieuwe seizoen van The Last of Us en de wens van Xbox om ook films en series te gaan maken. Dit alles en meer ga je zien en horen in de Einde van de Week Live van vrijdag 21 maart 2025.Hoeveel zin hebben we in tweede seizoen The Last of Us?In deze editie van EvdWL krijg je verder discussie over onder andere Kingdom Come Deliverance 2, de opmerkelijke uitspraken van de creatie van Super Smash en Silent Hill F.Scoor de Katana 15 gaming laptop nu voor een fijne prijsDeze week zet MSI hun Katana 15 in het zonnetje. Een dikke gaming laptop met onder de motorkap een 13e generatie Intel® Core™ i7 processor, een RTX 4070 videokaart, een 1TB SSD, een 15.6” Full HD paneel 144Hz en een 4-zone RGB toetsenbord. Kun je prima de hedendaagse games op spelen. Interesse in deze laptop? Check hier op de site van Azerty de specs en de prijs.LG Ultragear presenteert ‘s werelds snelste 27” 480 Hz QHD monitorZoals je weet zijn er een hoop presentatoren bij Gamekings erg happy met LG schermen en monitoren. Meerdere van ons hebben hun hardware thuis staan. Jelle sinds kort ook. En wel de LG Ultragear 27” OLED 480 Hz QHD gaming monitor. In deze video kun je de unboxing, installatie en kalibratie van deze forse knaap bekijken. Wil je meer info over de LG Ultragear 27” OLED 480 Hz QHD gaming monitor, dan is hier de pagina met alle ins en outs.Stap over naar KPN Glasvezel en ontvang een console naar keuzeKPN Glasvezel is terug van weg geweest met hun dikke actie: stap over naar KPN Glasvezel, neem een tweejarig abonnement en kies een PlayStation Slim, een Xbox Series S (1 TB) + 2 controllers of een Switch OLED als welkomstgeschenk. Heb je nog geen glasvezel in de straat liggen, dan kun je voor nu een normaal abonnement nemen die tegen de tijd dat er glasvezel ligt omgezet wordt. De huidige actie is nu dan wel geldig. Wil je meer info over de actie, hier vind je de website met alle ins & outs.Timestamps:00:00:00 Intro00:01:51 Huishoudelijke mededeling: MSI00:10:33 Wat heb jij de afgelopen week gespeeld? 00:16:05 Gisternacht was de Future Games Show. We checken paar van tofste trailers.00:31:39 The Last of Us seizoen 2 komt eraan, 13 april eerste deel. Daarom is er de seizoen 1 recap trailer.00:42:52 Super Smash Bro's creator Sakurai vindt dat Japanse developers zich voor de volle 100% op de Japanse markt en smaak moeten richten en niet die van het Westen.00:45:02 Silent Hill F kent geen vuurwapens. Alles wordt met de hand gedaan.00:49:10 F1 25 komt 30 mei uit, alsdus een leaker.00:51:38 Xbox wil ook films en series gaan maken.00:57:34 Atari komt op de markt met een horloge met vier klassieke games erop.00:58:31 BULLETTÎME: KPN01:06:02 De stelling van de week: Het succes van Split Fiction (2 miljoen verkochte exemplaren) maakt duidelijk dat er meer coop games moeten komen.01:07:15 Kingdom Come Deliverance 2 verkoopt 5 keer zoveel exemplaren als eerste deel.01:09:08 Life is Strange Double Exposure brengt te weinig op.01:11:12 Hollow Knight Silksong zou er wel eens aan kunnen komen.01:13:20 Ken Kuturagi heeft één van de zeer zeldzame Nintendo PlayStations in zijn kluis.01:15:13 BULLETTÎME: LG Ultragear.01:25:28 COOL OF SERIOUS UNCOOL?
Rgb and Mikey chop it about finally getting a chance get outside and get a round it , Frear Park updates and much more tune in on all podcast platforms. #518 #bogey #golf #podcast #bogeygolf #explore #fairway #golfer #golfputt #interview
Florida Mike the cohost of The Upstate Golf Guys and Conspiracy Chaos joins Rgb to talk all things golf conspiracy and greenery #518 #bogey #golf #podcast #bogeygolf #explore #fairway #golfer #golfputt #interview #florida #fore
“Eventually, my dream would be to simulate a virtual cell.”—Demis HassabisThe aspiration to build the virtual cell is considered to be equivalent to a moonshot for digital biology. Recently, 42 leading life scientists published a paper in Cell on why this is so vital, and how it may ultimately be accomplished. This conversation is with 2 of the authors, Charlotte Bunne, now at EPFL and Steve Quake, a Professor at Stanford University, who heads up science at the Chan-Zuckerberg Initiative The audio (above) is available on iTunes and Spotify. The full video is linked here, at the top, and also can be found on YouTube.TRANSCRIPT WITH LINKS TO AUDIO Eric Topol (00:06):Hello, it's Eric Topol with Ground Truths and we've got a really hot topic today, the virtual cell. And what I think is extraordinarily important futuristic paper that recently appeared in the journal Cell and the first author, Charlotte Bunne from EPFL, previously at Stanford's Computer Science. And Steve Quake, a young friend of mine for many years who heads up the Chan Zuckerberg Initiative (CZI) as well as a professor at Stanford. So welcome, Charlotte and Steve.Steve Quake (00:42):Thanks, Eric. It's great to be here.Charlotte Bunne:Thanks for having me.Eric Topol (00:45):Yeah. So you wrote this article that Charlotte, the first author, and Steve, one of the senior authors, appeared in Cell in December and it just grabbed me, “How to build the virtual cell with artificial intelligence: Priorities and opportunities.” It's the holy grail of biology. We're in this era of digital biology and as you point out in the paper, it's a convergence of what's happening in AI, which is just moving at a velocity that's just so extraordinary and what's happening in biology. So maybe we can start off by, you had some 42 authors that I assume they congregated for a conference or something or how did you get 42 people to agree to the words in this paper?Steve Quake (01:33):We did. We had a meeting at CZI to bring community members together from many different parts of the community, from computer science to bioinformatics, AI experts, biologists who don't trust any of this. We wanted to have some real contrarians in the mix as well and have them have a conversation together about is there an opportunity here? What's the shape of it? What's realistic to expect? And that was sort of the genesis of the article.Eric Topol (02:02):And Charlotte, how did you get to be drafting the paper?Charlotte Bunne (02:09):So I did my postdoc with Aviv Regev at Genentech and Jure Leskovec at CZI and Jure was part of the residency program of CZI. And so, this is how we got involved and you had also prior work with Steve on the universal cell embedding. So this is how everything got started.Eric Topol (02:29):And it's actually amazing because it's a who's who of people who work in life science, AI and digital biology and omics. I mean it's pretty darn impressive. So I thought I'd start off with a quote in the article because it kind of tells a story of where this could go. So the quote was in the paper, “AIVC (artificial intelligence virtual cell) has the potential to revolutionize the scientific process, leading to future breakthroughs in biomedical research, personalized medicine, drug discovery, cell engineering, and programmable biology.” That's a pretty big statement. So maybe we can just kind of toss that around a bit and maybe give it a little more thoughts and color as to what you were positing there.Steve Quake (03:19):Yeah, Charlotte, you want me to take the first shot at that? Okay. So Eric, it is a bold claim and we have a really bold ambition here. We view that over the course of a decade, AI is going to provide the ability to make a transformative computational tool for biology. Right now, cell biology is 90% experimental and 10% computational, roughly speaking. And you've got to do just all kinds of tedious, expensive, challenging lab work to get to the answer. And I don't think AI is going to replace that, but it can invert the ratio. So within 10 years I think we can get to biology being 90% computational and 10% experimental. And the goal of the virtual cell is to build a tool that'll do that.Eric Topol (04:09):And I think a lot of people may not understand why it is considered the holy grail because it is the fundamental unit of life and it's incredibly complex. It's not just all the things happening in the cell with atoms and molecules and organelles and everything inside, but then there's also the interactions the cell to other cells in the outside tissue and world. So I mean it's really quite extraordinary challenge that you've taken on here. And I guess there's some debate, do we have the right foundation? We're going to get into foundation models in a second. A good friend of mine and part of this whole I think process that you got together, Eran Segal from Israel, he said, “We're at this tipping point…All the stars are aligned, and we have all the different components: the data, the compute, the modeling.” And in the paper you describe how we have over the last couple of decades have so many different data sets that are rich that are global initiatives. But then there's also questions. Do we really have the data? I think Bo Wang especially asked about that. Maybe Charlotte, what are your thoughts about data deficiency? There's a lot of data, but do you really have what we need before we bring them all together for this kind of single model that will get us some to the virtual cell?Charlotte Bunne (05:41):So I think, I mean one core idea of building this AIVC is that we basically can leverage all experimental data that is overall collected. So this also goes back to the point Steve just made. So meaning that we basically can integrate across many different studies data because we have AI algorithms or the architectures that power such an AIVC are able to integrate basically data sets on many different scales. So we are going a bit away from this dogma. I'm designing one algorithm from one dataset to this idea of I have an architecture that can take in multiple dataset on multiple scales. So this will help us a bit in being somewhat efficient with the type of experiments that we need to make and the type of experiments we need to conduct. And again, what Steve just said, ultimately, we can very much steer which data sets we need to collect.Charlotte Bunne (06:34):Currently, of course we don't have all the data that is sufficient. I mean in particular, I think most of the tissues we have, they are healthy tissues. We don't have all the disease phenotypes that we would like to measure, having patient data is always a very tricky case. We have mostly non-interventional data, meaning we have very limited understanding of somehow the effect of different perturbations. Perturbations that happen on many different scales in many different environments. So we need to collect a lot here. I think the overall journey that we are going with is that we take the data that we have, we make clever decisions on the data that we will collect in the future, and we have this also self-improving entity that is aware of what it doesn't know. So we need to be able to understand how well can I predict something on this somewhat regime. If I cannot, then we should focus our data collection effort into this. So I think that's not a present state, but this will basically also guide the future collection.Eric Topol (07:41):Speaking of data, one of the things I think that's fascinating is we saw how AlphaFold2 really revolutionized predicting proteins. But remember that was based on this extraordinary resource that had been built, the Protein Data Bank that enabled that. And for the virtual cell there's no such thing as a protein data bank. It's so much more as you emphasize Charlotte, it's so much dynamic and these perturbations that are just all across the board as you emphasize. Now the human cell atlas, which currently some tens of millions, but going into a billion cells, we learned that it used to be 200 cell types. Now I guess it's well over 5,000 and that we have 37 trillion cells approximately in the average person adult's body is a formidable map that's being made now. And I guess the idea that you're advancing is that we used to, and this goes back to a statement you made earlier, Steve, everything we did in science was hypothesis driven. But if we could get computational model of the virtual cell, then we can have AI exploration of the whole field. Is that really the nuts of this?Steve Quake (09:06):Yes. A couple thoughts on that, maybe Theo Karaletsos, our lead AI person at CZI says machine learning is the formalism through which we understand high dimensional data and I think that's a very deep statement. And biological systems are intrinsically very high dimensional. You've got 20,000 genes in the human genome in these cell atlases. You're measuring all of them at the same time in each single cell. And there's a lot of structure in the relationships of their gene expression there that is just not evident to the human eye. And for example, CELL by GENE, our database that collects all the aggregates, all of the single cell transcriptomic data is now over a hundred million cells. And as you mentioned, we're seeing ways to increase that by an order of magnitude in the near future. The project that Jure Leskovec and I worked on together that Charlotte referenced earlier was like a first attempt to build a foundational model on that data to discover some of the correlations and structure that was there.Steve Quake (10:14):And so, with a subset, I think it was the 20 or 30 million cells, we built a large language model and began asking it, what do you understand about the structure of this data? And it kind of discovered lineage relationships without us teaching it. We trained on a matrix of numbers, no biological information there, and it learned a lot about the relationships between cell type and lineage. And that emerged from that high dimensional structure, which was super pleasing to us and really, I mean for me personally gave me the confidence to say this stuff is going to work out. There is a future for the virtual cell. It's not some made up thing. There is real substance there and this is worth investing an enormous amount of CZIs resources in going forward and trying to rally the community around as a project.Eric Topol (11:04):Well yeah, the premise here is that there is a language of life, and you just made a good case that there is if you can predict, if you can query, if you can generate like that. It is reminiscent of the famous Go game of Lee Sedol, that world champion and how the machine came up with a move (Move 37) many, many years ago that no human would've anticipated and I think that's what you're getting at. And the ability for inference and reason now to add to this. So Charlotte, one of the things of course is about, well there's two terms in here that are unfamiliar to many of the listeners or viewers of this podcast, universal representations (UR) and virtual instrument (VIs) that you make a pretty significant part of how you are going about this virtual cell model. So could you describe that and also the embeddings as part of the universal representation (UR) because I think embeddings, or these meaningful relationships are key to what Steve was just talking about.Charlotte Bunne (12:25):Yes. So in order to somewhat leverage very different modalities in order to leverage basically modalities that will take measurements across different scales, like the idea is that we have large, may it be transformer models that might be very different. If I have imaging data, I have a vision transformer, if I have a text data, I have large language models that are designed of course for DNA then they have a very wide context and so on and so forth. But the idea is somewhat that we have models that are connected through the scales of biology because those scales we know. We know which components are somewhat involved or in measurements that are happening upstream. So we have the somewhat interconnection or very large model that will be trained on many different data and we have this internal model representation that somewhat capture everything they've seen. And so, this is what we call those universal representation (UR) that will exist across the scales of biology.Charlotte Bunne (13:22):And what is great about AI, and so I think this is a bit like a history of AI in short is the ability to predict the last years, the ability to generate, we can generate new hypothesis, we can generate modalities that we are missing. We can potentially generate certain cellular state, molecular state have a certain property, but I think what's really coming is this ability to reason. So we see this in those very large language models, the ability to reason about a hypothesis, how we can test it. So this is what those instruments ultimately need to do. So we need to be able to simulate the change of a perturbation on a cellular phenotype. So on the internal representation, the universal representation of a cell state, we need to simulate the fact the mutation has downstream and how this would propagate in our representations upstream. And we need to build many different type of virtual instruments that allow us to basically design and build all those capabilities that ultimately the AI virtual cell needs to possess that will then allow us to reason, to generate hypothesis, to basically predict the next experiment to conduct to predict the outcome of a perturbation experiment to in silico design, cellular states, molecular states, things like that. And this is why we make the separation between internal representation as well as those instruments that operate on those representations.Eric Topol (14:47):Yeah, that's what I really liked is that you basically described the architecture, how you're going to do this. By putting these URs into the VIs, having a decoder and a manipulator and you basically got the idea if you can bring all these different integrations about which of course is pending. Now there are obviously many naysayers here that this is impossible. One of them is this guy, Philip Ball. I don't know if you read the language, How Life Works. Now he's a science journalist and he's a prolific writer. He says, “Comparing life to a machine, a robot, a computer, sells it short. Life is a cascade of processes, each with a distinct integrity and autonomy, the logic of which has no parallel outside the living world.” Is he right? There's no way to model this. It's silly, it's too complex.Steve Quake (15:50):We don't know, alright. And it's great that there's naysayers. If everyone agreed this was doable, would it be worth doing? I mean the whole point is to take risks and get out and do something really challenging in the frontier where you don't know the answer. If we knew that it was doable, I wouldn't be interested in doing it. So I personally am happy that there's not a consensus.Eric Topol (16:16):Well, I mean to capture people's imagination here, if you're successful and you marshal a global effort, I don't know who's going to pay for it because it's a lot of work coming here going forward. But if you can do it, the question here is right today we talk about, oh let's make an organoid so we can figure out how to treat this person's cancer or understand this person's rare disease or whatever. And instead of having to wait weeks for this culture and all the expense and whatnot, you could just do it in a computer and in silico and you have this virtual twin of a person's cells and their tissue and whatnot. So the opportunity here is, I don't know if people get, this is just extraordinary and quick and cheap if you can get there. And it's such a bold initiative idea, who will pay for this do you think?Steve Quake (17:08):Well, CZI is putting an enormous amount of resources into it and it's a major project for us. We have been laying the groundwork for it. We recently put together what I think is if not the largest, one of the largest GPU supercomputer clusters for nonprofit basic science research that came online at the end of last year. And in fact in December we put out an RFA for the scientific community to propose using it to build models. And so we're sharing that resource within the scientific community as I think you appreciate, one of the real challenges in the field has been access to compute resources and industry has it academia at a much lower level. We are able to be somewhere in between, not quite at the level of a private company but the tech company but at a level beyond what most universities are being able to do and we're trying to use that to drive the field forward. We're also planning on launching RFAs we this year to help drive this project forward and funding people globally on that. And we are building a substantial internal effort within CZI to help drive this project forward.Eric Topol (18:17):I think it has the looks of the human genome project, which at time as you know when it was originally launched that people thought, oh, this is impossible. And then look what happened. It got done. And now the sequence of genome is just a commodity, very relatively, very inexpensive compared to what it used to be.Steve Quake (18:36):I think a lot about those parallels. And I will say one thing, Philip Ball, I will concede him the point, the cells are very complicated. The genome project, I mean the sort of genius there was to turn it from a biology problem to a chemistry problem, there is a test tube with a chemical and it work out the structure of that chemical. And if you can do that, the problem is solved. I think what it means to have the virtual cell is much more complex and ambiguous in terms of defining what it's going to do and when you're done. And so, we have our work cut out for us there to try to do that. And that's why a little bit, I established our North Star and CZI for the next decade as understanding the mysteries of the cell and that word mystery is very important to me. I think the molecules, as you pointed out earlier are understood, genome sequenced, protein structure solved or predicted, we know a lot about the molecules. Those are if not solved problems, pretty close to being solved. And the real mystery is how do they work together to create life in the cell? And that's what we're trying to answer with this virtual cell project.Eric Topol (19:43):Yeah, I think another thing that of course is happening concurrently to add the likelihood that you'll be successful is we've never seen the foundation models coming out in life science as they have in recent weeks and months. Never. I mean, I have a paper in Science tomorrow coming out summarizing the progress about not just RNA, DNA, ligands. I mean the whole idea, AlphaFold3, but now Boltz and so many others. It's just amazing how fast the torrent of new foundation models. So Charlotte, what do you think accounts for this? This is unprecedented in life science to see foundation models coming out at this clip on evolution on, I mean you name it, design of every different molecule of life or of course in cells included in that. What do you think is going on here?Charlotte Bunne (20:47):So on the one hand, of course we benefit profits and inherit from all the tremendous efforts that have been made in the last decades on assembling those data sets that are very, very standardized. CELLxGENE is very somehow AI friendly, as you can say, it is somewhat a platform that is easy to feed into algorithms, but at the same time we actually also see really new building mechanisms, design principles of AI algorithms in itself. So I think we have understood that in order to really make progress, build those systems that work well, we need to build AI tools that are designed for biological data. So to give you an easy example, if I use a large language model on text, it's not going to work out of the box for DNA because we have different reading directions, different context lens and many, many, many, many more.Charlotte Bunne (21:40):And if I look at standard computer vision where we can say AI really excels and I'm applying standard computer vision, vision transformers on multiplex images, they're not going to work because normal computer vision architectures, they always expect the same three inputs, RGB, right? In multiplex images, I'm measuring up to 150 proteins potentially in a single experiment, but every study will measure different proteins. So I deal with many different scales like larger scales and I used to attention mechanisms that we have in usual computer vision. Transformers are not going to work anymore, they're not going to scale. And at the same time, I need to be completely flexible in whatever input combination of channel I'm just going to face in this experiment. So this is what we right now did for example, in our very first work, inheriting the design principle that we laid out in the paper AI virtual cell and then come up with new AI architectures that are dealing with these very special requirements that biological data have.Charlotte Bunne (22:46):So we have now a lot of computer scientists that work very, very closely have a very good understanding of biologists. Biologists that are getting much and much more into the computer science. So people who are fluent in both languages somewhat, that are able to now build models that are adopted and designed for biological data. And we don't just take basically computer vision architectures that work well on street scenes and try to apply them on biological data. So it's just a very different way of thinking about it, starting constructing basically specialized architectures, besides of course the tremendous data efforts that have happened in the past.Eric Topol (23:24):Yeah, and we're not even talking about just sequence because we've also got imaging which has gone through a revolution, be able to image subcellular without having to use any types of stains that would disrupt cells. That's another part of the deep learning era that came along. One thing I thought was fascinating in the paper in Cell you wrote, “For instance, the Short Read Archive of biological sequence data holds over 14 petabytes of information, which is 1,000 times larger than the dataset used to train ChatGPT.” I mean that's a lot of tokens, that's a lot of stuff, compute resources. It's almost like you're going to need a DeepSeek type of way to get this. I mean not that DeepSeek as its claim to be so much more economical, but there's a data challenge here in terms of working with that massive amount that is different than the human language. That is our language, wouldn't you say?Steve Quake (24:35):So Eric, that brings to mind one of my favorite quotes from Sydney Brenner who is such a wit. And in 2000 at the sort of early first flush of success in genomics, he said, biology is drowning in a sea of data and starving for knowledge. A very deep statement, right? And that's a little bit what the motivation was for putting the Short Read Archive statistic into the paper there. And again, for me, part of the value of this endeavor of creating a virtual cell is it's a tool to help us translate data into knowledge.Eric Topol (25:14):Yeah, well there's two, I think phenomenal figures in your Cell paper. The first one that kicks across the capabilities of the virtual cell and the second that compares the virtual cell to the real or the physical cell. And we'll link that with this in the transcript. And the other thing we'll link is there's a nice Atlantic article, “A Virtual Cell Is a ‘Holy Grail' of Science. It's Getting Closer.” That might not be quite close as next week or year, but it's getting close and that's good for people who are not well grounded in this because it's much more taken out of the technical realm. This is really exciting. I mean what you're onto here and what's interesting, Steve, since I've known you for so many years earlier in your career you really worked on omics that is being DNA and RNA and in recent times you've made this switch to cells. Is that just because you're trying to anticipate the field or tell us a little bit about your migration.Steve Quake (26:23):Yeah, so a big part of my career has been trying to develop new measurement technologies that'll provide insight into biology. And decades ago that was understanding molecules. Now it's understanding more complex biological things like cells and it was like a natural progression. I mean we built the sequencers, sequenced the genomes, done. And it was clear that people were just going to do that at scale then and create lots of data. Hopefully knowledge would get out of that. But for me as an academic, I never thought I'd be in the position I'm in now was put it that way. I just wanted to keep running a small research group. So I realized I would have to get out of the genome thing and find the next frontier and it became this intersection of microfluidics and genomics, which as you know, I spent a lot of time developing microfluidic tools to analyze cells and try to do single cell biology to understand their heterogeneity. And that through a winding path led me to all these cell atlases and to where we are now.Eric Topol (27:26):Well, we're fortunate for that and also with your work with CZI to help propel that forward and I think it sounds like we're going to need a lot of help to get this thing done. Now Charlotte, as a computer scientist now at EPFL, what are you going to do to keep working on this and what's your career advice for people in computer science who have an interest in digital biology?Charlotte Bunne (27:51):So I work in particular on the prospect of using this to build diagnostic tools and to make diagnostics in the clinic easier because ultimately we have somewhat limited capabilities in the hospital to run deep omics, but the idea of being able to somewhat map with a cheaper and lighter modality or somewhat diagnostic test into something much richer because a model has been seeing all those different data and can basically contextualize it. It's very interesting. We've seen all those pathology foundation models. If I can always run an H&E, but then decide when to run deeper diagnostics to have a better or more accurate prediction, that is very powerful and it's ultimately reducing the costs, but the precision that we have in hospitals. So my faculty position right now is co-located between the School of Life Sciences, School of Computer Science. So I have a dual affiliation and I'm affiliated to the hospitals to actually make this possible and as a career advice, I think don't be shy and stick to your discipline.Charlotte Bunne (28:56):I have a bachelor's in biology, but I never only did biology. I have a PhD in computer science, which you would think a bachelor in biology not necessarily qualifies you through. So I think this interdisciplinarity also requires you to be very fluent, very comfortable in reading many different styles of papers and publications because a publication in a computer science venue will be very, very different from the way we write in biology. So don't stick to your study program, but just be free in selecting whatever course gets you closer to the knowledge you need in order to do the research or whatever task you are building and working on.Eric Topol (29:39):Well, Charlotte, the way you're set up there with this coalescence of life science and computer science is so ideal and so unusual here in the US, so that's fantastic. That's what we need and that's really the underpinning of how you're going to get to the virtual cells, getting these two communities together. And Steve, likewise, you were an engineer and somehow you became one of the pioneers of digital biology way back before it had that term, this interdisciplinary, transdisciplinary. We need so much of that in order for you all to be successful, right?Steve Quake (30:20):Absolutely. I mean there's so much great discovery to be done on the boundary between fields. I trained as a physicist and kind of made my career this boundary between physics and biology and technology development and it's just sort of been a gift that keeps on giving. You've got a new way to measure something, you discover something new scientifically and it just all suggests new things to measure. It's very self-reinforcing.Eric Topol (30:50):Now, a couple of people who you know well have made some pretty big statements about this whole era of digital biology and I think the virtual cell is perhaps the biggest initiative of all the digital biology ongoing efforts, but Jensen Huang wrote, “for the first time in human history, biology has the opportunity to be engineering, not science.” And Demis Hassabis wrote or said, ‘we're seeing engineering science, you have to build the artifact of interest first, and then once you have it, you can use the scientific method to reduce it down and understand its components.' Well here there's a lot to do to understand its components and if we can do that, for example, right now as both of AI drug discoveries and high gear and there's umpteen numbers of companies working on it, but it doesn't account for the cell. I mean it basically is protein, protein ligand interactions. What if we had drug discovery that was cell based? Could you comment about that? Because that doesn't even exist right now.Steve Quake (32:02):Yeah, I mean I can say something first, Charlotte, if you've got thoughts, I'm curious to hear them. So I do think AI approaches are going to be very useful designing molecules. And so, from the perspective of designing new therapeutics, whether they're small molecules or antibodies, yeah, I mean there's a ton of investment in that area that is a near term fruit, perfect thing for venture people to invest in and there's opportunity there. There's been enough proof of principle. However, I do agree with you that if you want to really understand what happens when you drug a target, you're going to want to have some model of the cell and maybe not just the cell, but all the different cell types of the body to understand where toxicity will come from if you have on-target toxicity and whether you get efficacy on the thing you're trying to do.Steve Quake (32:55):And so, we really hope that people will use the virtual cell models we're going to build as part of the drug discovery development process, I agree with you in a little of a blind spot and we think if we make something useful, people will be using it. The other thing I'll say on that point is I'm very enthusiastic about the future of cellular therapies and one of our big bets at CZI has been starting the New York Biohub, which is aimed at really being very ambitious about establishing the engineering and scientific foundations of how to engineer completely, radically more powerful cellular therapies. And the virtual cell is going to help them do that, right? It's going to be essential for them to achieve that mission.Eric Topol (33:39):I think you're pointing out one of the most important things going on in medicine today is how we didn't anticipate that live cell therapy, engineered cells and ideally off the shelf or in vivo, not just having to take them out and work on them outside the body, is a revolution ongoing, and it's not just in cancer, it's in autoimmune diseases and many others. So it's part of the virtual cell need. We need this. One of the things that's a misnomer, I want you both to comment on, we keep talking about single cell, single cell. And there's a paper spatial multi-omics this week, five different single cell scales all integrated. It's great, but we don't get to single cell. We're basically looking at 50 cells, 100 cells. We're not doing single cell because we're not going deep enough. Is that just a matter of time when we actually are doing, and of course the more we do get down to the single or a few cells, the more insights we're going to get. Would you comment about that? Because we have all this literature on single cell comes out every day, but we're not really there yet.Steve Quake (34:53):Charlotte, do you want to take a first pass at that and then I can say something?Charlotte Bunne (34:56):Yes. So it depends. So I think if we look at certain spatial proteomics, we still have subcellular resolutions. So of course, we always measure many different cells, but we are able to somewhat get down to resolution where we can look at certain colocalization of proteins. This also goes back to the point just made before having this very good environment to study drugs. If I want to build a new drug, if I want to build a new protein, the idea of building this multiscale model allows us to actually simulate different, somehow binding changes and binding because we simulate the effect of a drug. Ultimately, the redouts we have they are subcellular. So of course, we often in the spatial biology, we often have a bit like methods that are rather coarse they have a spot that averages over certain some cells like hundreds of cells or few cells.Charlotte Bunne (35:50):But I think we also have more and more technologies that are zooming in that are subcellular where we can actually tag or have those probe-based methods that allow us to zoom in. There's microscopy of individual cells to really capture them in 3D. They are of course not very high throughput yet, but it gives us also an idea of the morphology and how ultimately morphology determine certain somehow cellular properties or cellular phenotype. So I think there's lots of progress also on the experimental and that ultimately will back feed into the AI virtual cell, those models that will be fed by those data. Similarly, looking at dynamics, right, looking at live imaging of individual cells of their morphological changes. Also, this ultimately is data that we'll need to get a better understanding of disease mechanisms, cellular phenotypes functions, perturbation responses.Eric Topol (36:47):Right. Yes, Steve, you can comment on that and the amazing progress that we have made with space and time, spatial temporal resolution, spatial omics over these years, but that we still could go deeper in terms of getting to individual cells, right?Steve Quake (37:06):So, what can we do with a single cell? I'd say we are very mature in our ability to amplify and sequence the genome of a single cell, amplify and sequence the transcriptome of a single cell. You can ask is one cell enough to make a biological conclusion? And maybe I think what you're referring to is people want to see replicates and so you can ask how many cells do you need to see to have confidence in any given biological conclusion, which is a reasonable thing. It's a statistical question in good science. I think I've been very impressed with how the mass spec people have been doing recently. I think they've finally cracked the ability to look at proteins from single cells and they can look at a couple thousand proteins. That was I think one of these Nature method of the year things at the end of last year and deep visual proteomics.Eric Topol (37:59):Deep visual proteomics, yes.Steve Quake (38:00):Yeah, they are over the hump. Yeah, they are over the hump with single cell measurements. Part of what's missing right now I think is the ability to reliably do all of that on the same cell. So this is what Charlotte was referring to be able to do sort of multi-modal measurements on single cells. That's kind of in its infancy and there's a few examples, but there's a lot more work to be done on that. And I think also the fact that these measurements are all destructive right now, and so you're losing the ability to look how the cells evolve over time. You've got to say this time point, I'm going to dissect this thing and look at a state and I don't get to see what happens further down the road. So that's another future I think measurement challenge to be addressed.Eric Topol (38:42):And I think I'm just trying to identify some of the multitude of challenges in this extraordinarily bold initiative because there are no shortage and that's good about it. It is given people lots of work to do to overcome, override some of these challenges. Now before we wrap up, besides the fact that you point out that all the work has to be done and be validated in real experiments, not just live in a virtual AI world, but you also comment about the safety and ethics of this work and assuming you're going to gradually get there and be successful. So could either or both of you comment about that because it's very thoughtful that you're thinking already about that.Steve Quake (41:10):As scientists and members of the larger community, we want to be careful and ensure that we're interacting with people who said policy in a way that ensures that these tools are being used to advance the cause of science and not do things that are detrimental to human health and are used in a way that respects patient privacy. And so, the ethics around how you use all this with respect to individuals is going to be important to be thoughtful about from the beginning. And I also think there's an ethical question around what it means to be publishing papers and you don't want people to be forging papers using data from the virtual cell without being clear about where that came from and pretending that it was a real experiment. So there's issues around those sorts of ethics as well that need to be considered.Eric Topol (42:07):And of those 40 some authors, do you around the world, do you have the sense that you all work together to achieve this goal? Is there kind of a global bonding here that's going to collaborate?Steve Quake (42:23):I think this effort is going to go way beyond those 40 authors. It's going to include a much larger set of people and I'm really excited to see that evolve with time.Eric Topol (42:31):Yeah, no, it's really quite extraordinary how you kick this thing off and the paper is the blueprint for something that we are all going to anticipate that could change a lot of science and medicine. I mean we saw, as you mentioned, Steve, how that deep visual proteomics (DVP) saved lives. It was what I wrote a spatial medicine, no longer spatial biology. And so, the way that this can change the future of medicine, I think a lot of people just have to have a little bit of imagination that once we get there with this AIVC, that there's a lot in store that's really quite exciting. Well, I think this has been an invigorating review of that paper and some of the issues surrounding it. I couldn't be more enthusiastic for your success and ultimately where this could take us. Did I miss anything during the discussion that we should touch on before we wrap up?Steve Quake (43:31):Not from my perspective. It was a pleasure as always Eric, and a fun discussion.Charlotte Bunne (43:38):Thanks so much.Eric Topol (43:39):Well thank you both and all the co-authors of this paper. We're going to be following this with the great interest, and I think for most people listening, they may not know that this is in store for the future. Someday we will get there. I think one of the things to point out right now is the models we have today that large language models based on transformer architecture, they're going to continue to evolve. We're already seeing so much in inference and ability for reasoning to be exploited and not asking for prompts with immediate answers, but waiting for days to get back. A lot more work from a lot more computing resources. But we're going to get models in the future to fold this together. I think that's one of the things that you've touched on the paper so that whatever we have today in concert with what you've laid out, AI is just going to keep getting better.Eric Topol (44:39):The biology that these foundation models are going to get broader and more compelling as to their use cases. So that's why I believe in this. I don't see this as a static situation right now. I just think that you're anticipating the future, and we will have better models to be able to integrate this massive amount of what some people would consider disparate data sources. So thank you both and all your colleagues for writing this paper. I don't know how you got the 42 authors to agree to it all, which is great, and it's just a beginning of something that's a new frontier. So thanks very much.Steve Quake (45:19):Thank you, Eric.**********************************************Thanks for listening, watching or reading Ground Truths. Your subscription is greatly appreciated.If you found this podcast interesting please share it!That makes the work involved in putting these together especially worthwhile.All content on Ground Truths—newsletters, analyses, and podcasts—is free, open-access, with no ads..Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. And such support is becoming more vital In light of current changes of funding by US biomedical research at NIH and other governmental agencies.Thanks to my producer Jessica Nguyen and to Sinjun Balabanoff for audio and video support at Scripps Research. Get full access to Ground Truths at erictopol.substack.com/subscribe
The new RCS messaging standard makes encryption universal, and even Apple is getting on the bandwagon. OpenAI calls for a US ban of DeepSeek. Is Apple about to turn your AirPods into the Universal Translator from Star Trek? And, of course, The Weekend Longreads Suggestions.Sponsors:FactorMeals.com/factorpodcast and code FACTORPODCASTLinks:Apple will soon support encrypted RCS messaging with Android users (The Verge)OpenAI calls DeepSeek ‘state-controlled,' calls for bans on ‘PRC-produced' models (TechCrunch)Apple Plans AirPods Feature That Can Live-Translate Conversations (Bloomberg)Gemini can now personalize its answers based on your search history (The Verge)Sony's new RGB backlight tech absolutely smokes regular Mini LED TVs (The Verge)Weekend Longreads Suggestions:‘Ne Zha 2's $2B+ Box Office Run: How It Happened And What Does Blockbuster Behemoth Mean For China & Hollywood Ahead (Deadline)The End Of Children (The New Yorker)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Rgb and Mikey breakdown front 9 of our home course Frear Park in Troy New York. We also got into are recent mini golf outing !! Season can't get here fast enough #518 #bogey #golf #podcast #bogeygolf #explore #fairway #golfer #golfputt #interview
As the global population ages, the demand for innovative solutions to support the health and well-being of older adults has intensified. Among the myriad of challenges faced by this demographic, cognitive decline stands out as a pressing concern. With conditions such as Alzheimer's disease and other forms of dementia affecting millions, the need for effective monitoring and early intervention has never been more critical. In this context, artificial intelligence (AI) from AITCare has emerged as a powerful tool, particularly in the realm of sleep monitoring, offering a promising avenue for enhancing elderly care.Understanding the Importance of Sleep in Cognitive HealthSleep plays a vital role in overall health, particularly for older adults. Research has shown that sleep-wake disorders can be early indicators of cognitive decline. Conditions such as insomnia, hypersomnia, and sleep apnea not only disrupt rest but can also exacerbate cognitive issues. As older adults often experience changes in sleep patterns, monitoring these variations can provide crucial insights into their cognitive health. By identifying sleep disturbances early, caregivers can implement preventive measures that may mitigate the progression of cognitive decline.The Role of AI in Sleep MonitoringThe integration of AI into sleep monitoring systems represents a significant advancement in elderly care. AITCare is focused on using AI to develop non-invasive monitoring systems tailored for older adults. This system employs a combination of sensors, including motion detectors, thermometers, and RGB cameras, to continuously monitor sleep patterns without requiring direct interaction from the user. This is particularly beneficial for older adults who may be unfamiliar or uncomfortable with complex technology.The AI model developed by AITCare is designed to analyze 51 data points on the body, allowing for a comprehensive understanding of an individual's sleep behavior. This model is capable of detecting minute movements and changes in body position, which are critical for assessing sleep quality. For instance, it can identify if a person is sleeping on their side, which may impact blood circulation, or if they are experiencing restlessness throughout the night. By creating a detailed profile of an individual's sleep patterns over a week, the system can tailor its analysis to account for the unique characteristics of each user.Addressing Privacy ConcernsOne of the challenges associated with deploying monitoring technology in the homes of older adults is the concern over privacy. Many elderly individuals may be apprehensive about having cameras or sensors in their living spaces. AITCare has taken steps to address these concerns by ensuring that the installation of cameras is unobtrusive and that the data collected is used solely for the purpose of monitoring health. By placing cameras in ceilings and utilizing non-invasive technology, the system respects the privacy of users while still providing essential health insights.The Future of Elderly CareAs this AI-driven sleep monitoring technology progresses through pilot stages and moves toward wider implementation, it holds the potential to revolutionize elderly care. With approximately 20 million individuals aged 80 and above in the United States alone, the impact of such innovations could be profound. By providing caregivers with real-time data on sleep patterns and potential cognitive decline, these systems empower families and healthcare providers to make informed decisions about care and intervention.Conclusion: Using AI to Improve Elder HealthIn conclusion, the application of AI from AITCare in monitoring sleep for elderly care represents a significant leap forward in addressing the challenges of cognitive decline. By harnessing the power of technology to provide non-invasive, continuous monitoring, we can enhance the quality of life for older adults and support their caregivers in delivering effective care. As we continue to explore the intersection of technology and healthcare, the potential for AI to transform elderly care remains vast and promising.Interview by Marlo Anderson of The Tech Ranch.Sponsored by: Get $5 to protect your credit card information online with Privacy. Amazon Prime gives you more than just free shipping. Get free music, TV shows, movies, videogames and more. The most flexible tools for podcasting. Get a 30 day free trial of storage and statistics.
As the global population ages, the demand for innovative solutions to support the health and well-being of older adults has intensified. Among the myriad of challenges faced by this demographic, cognitive decline stands out as a pressing concern. With conditions such as Alzheimer's disease and other forms of dementia affecting millions, the need for effective monitoring and early intervention has never been more critical. In this context, artificial intelligence (AI) from AITCare has emerged as a powerful tool, particularly in the realm of sleep monitoring, offering a promising avenue for enhancing elderly care.Understanding the Importance of Sleep in Cognitive HealthSleep plays a vital role in overall health, particularly for older adults. Research has shown that sleep-wake disorders can be early indicators of cognitive decline. Conditions such as insomnia, hypersomnia, and sleep apnea not only disrupt rest but can also exacerbate cognitive issues. As older adults often experience changes in sleep patterns, monitoring these variations can provide crucial insights into their cognitive health. By identifying sleep disturbances early, caregivers can implement preventive measures that may mitigate the progression of cognitive decline.The Role of AI in Sleep MonitoringThe integration of AI into sleep monitoring systems represents a significant advancement in elderly care. AITCare is focused on using AI to develop non-invasive monitoring systems tailored for older adults. This system employs a combination of sensors, including motion detectors, thermometers, and RGB cameras, to continuously monitor sleep patterns without requiring direct interaction from the user. This is particularly beneficial for older adults who may be unfamiliar or uncomfortable with complex technology.The AI model developed by AITCare is designed to analyze 51 data points on the body, allowing for a comprehensive understanding of an individual's sleep behavior. This model is capable of detecting minute movements and changes in body position, which are critical for assessing sleep quality. For instance, it can identify if a person is sleeping on their side, which may impact blood circulation, or if they are experiencing restlessness throughout the night. By creating a detailed profile of an individual's sleep patterns over a week, the system can tailor its analysis to account for the unique characteristics of each user.Addressing Privacy ConcernsOne of the challenges associated with deploying monitoring technology in the homes of older adults is the concern over privacy. Many elderly individuals may be apprehensive about having cameras or sensors in their living spaces. AITCare has taken steps to address these concerns by ensuring that the installation of cameras is unobtrusive and that the data collected is used solely for the purpose of monitoring health. By placing cameras in ceilings and utilizing non-invasive technology, the system respects the privacy of users while still providing essential health insights.The Future of Elderly CareAs this AI-driven sleep monitoring technology progresses through pilot stages and moves toward wider implementation, it holds the potential to revolutionize elderly care. With approximately 20 million individuals aged 80 and above in the United States alone, the impact of such innovations could be profound. By providing caregivers with real-time data on sleep patterns and potential cognitive decline, these systems empower families and healthcare providers to make informed decisions about care and intervention.Conclusion: Using AI to Improve Elder HealthIn conclusion, the application of AI from AITCare in monitoring sleep for elderly care represents a significant leap forward in addressing the challenges of cognitive decline. By harnessing the power of technology to provide non-invasive, continuous monitoring, we can enhance the quality of life for older adults and support their caregivers in delivering effective care. As we continue to explore the intersection of technology and healthcare, the potential for AI to transform elderly care remains vast and promising.Interview by Marlo Anderson of The Tech Ranch.Sponsored by: Get $5 to protect your credit card information online with Privacy. Amazon Prime gives you more than just free shipping. Get free music, TV shows, movies, videogames and more. The most flexible tools for podcasting. Get a 30 day free trial of storage and statistics.
Rgb is joined by the owner founder of Daddyz Caddyz Daniella and Julie to discuss their latest project where they will bring to any golf event you have going on!!They are perfect for every tournament or corporate and private events. I don't know if golf is ready for Daddy'z Caddy'z but they're here and you can find them on instagram to book your event!! #518 #bogey #bogeygolf #explore #fairway #golf #golfer #golfputt #interview #podcast #caligirls #daddyzcaddyz #smokeshows
In an era where convenience and efficiency are paramount in household management, the emergence of advanced robotic cleaning technology has transformed the way we approach cleaning tasks. The Eureka J15 Pro Max Ultra stands at the forefront of this innovation, showcasing a blend of sophisticated features that enhance its functionality and user experience. With its integration of LiDAR mapping technology, dual-camera system, powerful suction capabilities, and versatile mopping functions, the J15 Pro Max Ultra represents a significant leap forward in robotic floor cleaning.LiDAR Mapping TechnologyAt the heart of the Eureka J15 Pro Max Ultra's advanced cleaning capabilities is its LiDAR (Light Detection and Ranging) technology. This cutting-edge feature allows the robot to create a precise map of its environment, enabling it to navigate efficiently throughout the home. Unlike traditional robotic vacuums that may rely solely on random navigation, the J15 Pro Max Ultra utilizes LiDAR to systematically scan and understand the layout of a room. This mapping capability not only enhances the robot's efficiency but also ensures that it can clean every corner of a space without missing spots.The LiDAR system operates by emitting laser pulses and measuring the time it takes for them to bounce back, allowing the robot to detect obstacles and create a three-dimensional representation of its surroundings. This is particularly beneficial for users who may want to run the vacuum at night, as the LiDAR continues to function effectively in low-light conditions. This addresses a common issue with traditional vacuums that may bump into objects in the dark due to limited visibility.Dual-Camera SystemAnother standout feature of the Eureka J15 Pro Max Ultra is its dual-camera system, which includes both an RGB camera and an infrared camera. The RGB camera provides high-definition visual recognition, similar to that of a smartphone, allowing the robot to identify and interact with pets and other objects in its path. However, the true innovation lies in the infrared camera, which excels in low-light environments. This camera can detect objects and even transparent liquids that might otherwise go unnoticed by the human eye or traditional RGB cameras.The inclusion of this dual-camera system significantly enhances the J15 Pro Max Ultra's object detection capabilities. It minimizes the likelihood of collisions and ensures that the robot can effectively navigate around furniture and other obstacles. Additionally, the infrared camera's ability to detect transparent liquids adds an extra layer of safety, preventing potential hazards in the home.Powerful Suction CapabilitiesIn terms of performance, the Eureka J15 Pro Max Ultra boasts an impressive suction power of 22,000 Pascal. This level of suction is comparable to some traditional canister vacuums, making the J15 Pro Max Ultra a formidable competitor in the cleaning appliance market. The powerful suction ensures that a wide range of debris, from dust and pet hair to larger particles, is effectively captured during cleaning sessions. This capability is particularly advantageous for households with pets or children, where messes can accumulate quickly.Versatile Mopping FunctionsThe J15 Pro Max Ultra goes beyond vacuuming, offering a dual-functionality that includes mopping capabilities. As modern cleaning demands evolve, many robotic vacuums have begun to incorporate mopping features, and the J15 Pro Max Ultra is no exception. It is equipped with an extendable mop that raises automatically when the robot detects carpeted areas, ensuring that it can effectively clean hardwood floors without leaving behind moisture.This innovative design not only enhances cleaning efficiency but also provides a comprehensive cleaning experience. The side brush, which is also extendable, allows the robot to reach corners and edges that are often neglected by traditional cleaning methods. This attention to detail ensures a thorough clean, leaving no spot overlooked.ConclusionThe Eureka J15 Pro Max Ultra represents a significant advancement in robotic cleaning technology, combining sophisticated features that enhance its functionality and user experience. With its LiDAR mapping technology, dual-camera system, powerful suction capabilities, and versatile mopping functions, the J15 Pro Max Ultra is not just a vacuum; it is a comprehensive cleaning solution that adapts to the needs of modern households. As technology continues to evolve, the J15 Pro Max Ultra stands as a testament to the potential of robotics in simplifying and improving our daily lives. In a world where time is precious, the Eureka J15 Pro Max Ultra offers a glimpse into the future of home cleaning-efficient, effective, and effortlessly integrated into our lives.Interview by Marlo Anderson of The Tech Ranch.Sponsored by: Get $5 to protect your credit card information online with Privacy. Amazon Prime gives you more than just free shipping. Get free music, TV shows, movies, videogames and more. The most flexible tools for podcasting. Get a 30 day free trial of storage and statistics.
In an era where convenience and efficiency are paramount in household management, the emergence of advanced robotic cleaning technology has transformed the way we approach cleaning tasks. The Eureka J15 Pro Max Ultra stands at the forefront of this innovation, showcasing a blend of sophisticated features that enhance its functionality and user experience. With its integration of LiDAR mapping technology, dual-camera system, powerful suction capabilities, and versatile mopping functions, the J15 Pro Max Ultra represents a significant leap forward in robotic floor cleaning.LiDAR Mapping TechnologyAt the heart of the Eureka J15 Pro Max Ultra's advanced cleaning capabilities is its LiDAR (Light Detection and Ranging) technology. This cutting-edge feature allows the robot to create a precise map of its environment, enabling it to navigate efficiently throughout the home. Unlike traditional robotic vacuums that may rely solely on random navigation, the J15 Pro Max Ultra utilizes LiDAR to systematically scan and understand the layout of a room. This mapping capability not only enhances the robot's efficiency but also ensures that it can clean every corner of a space without missing spots.The LiDAR system operates by emitting laser pulses and measuring the time it takes for them to bounce back, allowing the robot to detect obstacles and create a three-dimensional representation of its surroundings. This is particularly beneficial for users who may want to run the vacuum at night, as the LiDAR continues to function effectively in low-light conditions. This addresses a common issue with traditional vacuums that may bump into objects in the dark due to limited visibility.Dual-Camera SystemAnother standout feature of the Eureka J15 Pro Max Ultra is its dual-camera system, which includes both an RGB camera and an infrared camera. The RGB camera provides high-definition visual recognition, similar to that of a smartphone, allowing the robot to identify and interact with pets and other objects in its path. However, the true innovation lies in the infrared camera, which excels in low-light environments. This camera can detect objects and even transparent liquids that might otherwise go unnoticed by the human eye or traditional RGB cameras.The inclusion of this dual-camera system significantly enhances the J15 Pro Max Ultra's object detection capabilities. It minimizes the likelihood of collisions and ensures that the robot can effectively navigate around furniture and other obstacles. Additionally, the infrared camera's ability to detect transparent liquids adds an extra layer of safety, preventing potential hazards in the home.Powerful Suction CapabilitiesIn terms of performance, the Eureka J15 Pro Max Ultra boasts an impressive suction power of 22,000 Pascal. This level of suction is comparable to some traditional canister vacuums, making the J15 Pro Max Ultra a formidable competitor in the cleaning appliance market. The powerful suction ensures that a wide range of debris, from dust and pet hair to larger particles, is effectively captured during cleaning sessions. This capability is particularly advantageous for households with pets or children, where messes can accumulate quickly.Versatile Mopping FunctionsThe J15 Pro Max Ultra goes beyond vacuuming, offering a dual-functionality that includes mopping capabilities. As modern cleaning demands evolve, many robotic vacuums have begun to incorporate mopping features, and the J15 Pro Max Ultra is no exception. It is equipped with an extendable mop that raises automatically when the robot detects carpeted areas, ensuring that it can effectively clean hardwood floors without leaving behind moisture.This innovative design not only enhances cleaning efficiency but also provides a comprehensive cleaning experience. The side brush, which is also extendable, allows the robot to reach corners and edges that are often neglected by traditional cleaning methods. This attention to detail ensures a thorough clean, leaving no spot overlooked.ConclusionThe Eureka J15 Pro Max Ultra represents a significant advancement in robotic cleaning technology, combining sophisticated features that enhance its functionality and user experience. With its LiDAR mapping technology, dual-camera system, powerful suction capabilities, and versatile mopping functions, the J15 Pro Max Ultra is not just a vacuum; it is a comprehensive cleaning solution that adapts to the needs of modern households. As technology continues to evolve, the J15 Pro Max Ultra stands as a testament to the potential of robotics in simplifying and improving our daily lives. In a world where time is precious, the Eureka J15 Pro Max Ultra offers a glimpse into the future of home cleaning-efficient, effective, and effortlessly integrated into our lives.Interview by Marlo Anderson of The Tech Ranch.Sponsored by: Get $5 to protect your credit card information online with Privacy. Amazon Prime gives you more than just free shipping. Get free music, TV shows, movies, videogames and more. The most flexible tools for podcasting. Get a 30 day free trial of storage and statistics.
Is America losing its grip as a film production powerhouse? We break down surprising survey results revealing the top global production hubs - with the U.S. notably absent from the top five. We also dive into Promise AI's acquisition of Curious Refuge and what truly AI-native production studios might look like compared to traditional VFX pipelines. Plus, discover how a simple $70 RGB color sensor could become an essential problem-solving tool for virtual production sets.
Rgb is joined by the owner and founders of ATHLETHC , John and GW to discuss there new performance mints. They introduce a really cool product that's fast acting controls dosage and really fits the need of not only athletes but just everyday lifestyle. Great conversation with the guys about some of there business partnerships and other ventures to getting Rgb thinking about trying some MMA #518 #bogey #bogeygolf #explore #fairway #golf #golfer #golfputt #interview #podcast #rogan #athlethc Very excited to announce our new partnership with www.Athlethc.com by using promo code “puff” at checkout for an exclusive discount
Rgb brings you a solo episode talking about the mental state of golf and staying focused for a complete round. Talks about comparing the approach to golf to other sports. #518 #bogey #bogeygolf #explore #fairway #golf #golfer #golfputt #interview #podcast
The hidden tale of the Game Wizard for the SNES leads us to reminisce about Romantic Robot's Multiface devices. More youngsters are looking to disconnect with offline gaming. Clever people are modding CRT screens to accept RGB signals. We are sponsored by Sega Mania magazine this week. Now on issue 8 which covers Sega events from the latter half of 1995. Visit https://www.sega-mania.com/ where you can find every issue. 00:00 - Show Opening 06:56 - You're A Wizard Mario Story Link: https://www.xda-developers.com/the-game-wizards-hidden-tale/ 21:21 - Switch On To Switch Off Story Link: https://www.theguardian.com/games/2025/feb/15/theres-no-stress-gamers-go-offline-in-retro-console-revival Additional Link: https://retrosix.co.uk/ Never Knows Best Link: https://www.youtube.com/watch?v=Y2QgQtoGHRY 36:48 - Dave's Housekeeping - News links found below 45:17 - DIY RGB CRT ASAP….LOL Story Link: https://www.howtogeek.com/how-retro-enthusiasts-are-upgrading-crt-tvs-with-rgb-mods/ 55:31 - Community Question of the Week
Kate explores the power of color in lighting design—how it shapes human experiences, evokes emotion, and influences spatial perception. Drawing from her background in theatrical and architectural lighting, she shares insights on the intentional use of color as a storytelling tool.From museum exhibits to built environments, Kate discusses how light enhances materials, the cultural significance of color, and why thoughtful color selection is often more effective than color-changing lighting. Whether you're a designer, architect, or simply fascinated by how light impacts our world, this episode will change the way you see color.Topics Covered Theatrical vs. architectural lighting design The emotional and psychological effects of color The role of daylight and natural color variations How historical architecture was designed with lighting in mind Using light to enhance materials rather than overpower them Cultural perceptions of color The importance of intentionality in color selection Technical advances in color lighting and controls Balancing aesthetics and practicality in lighting projects Sustainability and responsible color application in lightingKey Takeaways Color in lighting is more than just RGB. Color is present in all light, and even subtle shifts in white light can dramatically impact perception. Lighting is a storytelling tool. The way color interacts with a space, material, and time of day shapes how people feel and engage with an environment. Cultural and contextual meaning of color matters. Different cultures perceive colors differently, and designers must consider these associations when making choices. Static vs. dynamic color use. Not all projects require dynamic color-changing lighting; sometimes, carefully selecting a fixed hue is more effective. Lighting design is a team effort. Successful implementation requires collaboration between lighting designers, architects, and other stakeholders.
Rgb is joined by the Golf Buccaneer (Jack) to talk about his golf history and current page. We also talk about his golf experiences on the west coast. He is starting his new venture into creating pouches for range finders and other golf items. #518 #bogey #bogeygolf #explore #fairway #golf #golfer #golfputt #interview
Rgb and Mikey back with another episode tell few old school stories followed up by #wtf did I watch at #nba #allstarweekend Rgb was not impressed with the format !! We were impressed with team USA hockey 3 fights in first 9 seconds to set the tone !! #518 #bogey #bogeygolf #explore #fairway #golf #golfer #golfputt #interview #podcast #fyp #goodgolf #golfgames #playinggolf
Rgb is joined by Susan owner of Mrs. Incredible Edible to discuss her journey in the canna industry as well as her new company and some of the products they offer that are a game changer in the medical world. #518 #bogey #bogeygolf #explore #fairway #golf #golfer #golfputt
Rgb breaks down recent vacation the. Boys talk some current events
Welcome back to The Totally Wholesome (Not Dirty) Podcast!
就在1990年的2月14号情人节这一天,旅行者1号开始执行这个复杂的拍摄任务。你想啊,虽然旅行者1号的相机没有被关闭,但是,也是很多年不用了,为了这次拍摄,相机启动预热了足足3个小时。拍摄全家福应该是用广角相机,然后用长焦对着每个天体拍摄特写。然后把广角照片拉大,把特写贴到对应的行星位置。既能保证视野的宽广,也能保证行星的清晰度。这两台相机前前后后要拍60多张照片,然后发回地球做拼接。我们现在熟知的那张著名的暗淡的蓝点,就是其中的一张特写照片。现在旅行者1号已经非常遥远,拍摄这些行星需要长时间的曝光才能获得可接受的图像质量。同时,随着距离的增加,通信能力也会减弱,限制了成像系统可以使用的数量亮。拍摄的照片太大,回传速度太慢也不行,需要权衡考虑。在拍完这套全家福之后,旅行者1号的相机就彻底休息了,以后再也用不上了,反正未来的任务也不可能接近任何已知的重要天体了,其他的仪器还要继续长时间工作,所以不论是电力也好,计算能力也好,都要留给其他的仪器了。拍摄完的这些照片数据最初存储在机载磁带里。由于深空探测网络的主要工作被分配给了麦哲伦号和伽利略号任务,只能分出一小部分时间对准旅行者1号,所以只能等到分配给旅行者号项目的时间段,才能开始发送数据。而且距离远,数据传输极慢,在1990年3月至5月期间,旅行者1号将60帧图像传回地球,前后花了两个月时间。发送回的照片都是各个波段的单色图像。要拍摄彩色照片,需要用蓝色、绿色、紫色三张照片来叠加。有人奇怪,怎么不是RGB啊,红色去哪儿了?紫色就是蓝色与红色的叠加,所以紫色减去蓝色,就是红色。这三张照片的曝光时间是0.72秒、0.48秒和0.72秒。《暗淡的蓝点》这张著名的照片,就是这么拼出来的。2020年,也就是全家福拍摄30周年的时候,NASA又发布了用最新技术重新拼接的照片,颜色做了校正,而且噪音也少了很多。这张照片叫做《重访暗淡蓝点》。
What happens when a national Taekwondo champion trades in bruises for high heels and gravity-defying moves? Meet Caroline—a badass pole instructor and puppy school trainer—who joins Molly for a deep dive into the world of pole dancing, body confidence, and breaking stigmas.
In this episode of the CEDIA Podcast, host Walt Zerbe, senior director of technology and standards, explores the latest advancements in video technology with guest Michael Heiss, also known as "Captain Video." They discuss key topics from CES, including HDMI 2.2 and the Lip Latency Indication Protocol (LIP). Michael explains the significant improvements in HDMI 2.2, such as increased bandwidth for higher resolutions and frame rates. They also delve into AI's role in enhancing picture quality and the importance of understanding new technologies. The episode emphasizes continuous learning and staying informed about industry trends. Timestamps by PodSqueezeIntroduction to the Podcast (00:00:01) Lip Latency Indication Protocol Overview (00:00:07) An explanation of the Lift Latency Indication Protocol and its purpose in reducing sync errors. Introduction of Hosts (00:00:57) Walt Kirby introduces himself and guest Michael Heiss, highlighting their excitement about CES. Reflections on CES (00:01:18) Discussion of the overwhelming amount of information and advancements in video technology at CES. Consumer Insights on Video Technology (00:02:16) Michael shares insights on consumer interest in new video technology and potential purchasing recommendations. HDMI 2.2 Announcement (00:03:04) Discussion begins on HDMI 2.2, its improvements over HDMI 2.1, and implications for video transport. Technical Specifications of HDMI 2.2 (00:03:36) Detailed comparison of HDMI 2.2's speed and capabilities versus previous standards and DisplayPort. Market Impact of HDMI 2.2 (00:05:30) Exploration of HDMI 2.2's relevance in consumer markets and its potential applications in various industries. Challenges in HDMI 2.2 Adoption (00:06:06) Discussion on the timeline and challenges of implementing HDMI 2.2 technology in products. Future of Video Technology (00:08:24) Considerations for future-proofing installations with HDMI 2.2 and the importance of fiber optics. Introduction to Lift Latency Indication Protocol (00:09:35) A deeper dive into the Lift Latency Indication Protocol and its role in video formatting. Importance of Sync in Video Processing (00:11:12) Discussion of lip sync issues and the complexities of latency in video and audio processing. Complications of Latency Perception (00:13:05) Insights on how latency affects viewer experience, particularly in music and video synchronization. Humorous Take on Lip Sync (00:14:11) A lighthearted exchange about the naming of the Lift Latency Indication Protocol and its acronym. AI and Lip Sync Issues (00:15:08) Discussion on the potential for metadata-based lip sync solutions in video technology. AI Applications at CES (00:16:35) Insights into the emergence of AI applications showcased at CES, particularly by LG and Samsung. AI in Video Quality (00:18:40) Exploration of AI's role in enhancing video quality through background adjustments. Predictive AI and Daily Life (00:19:45) Discussion on the implications of predictive AI in everyday tasks and its potential downsides. AI Dependency and Privacy (00:22:46) Concerns about AI dependency, especially during power outages and its implications for privacy. Samsung Galaxy Phone Controversy (00:24:10) Controversy surrounding Samsung's moon photography feature and its implications for AI in consumer devices. Leading TV Brands at CES (00:25:39) Overview of leading TV brands showcased at CES, including LG, Samsung, Hisense, and TCL. AI Engines in TV Brands (00:27:54) Comparison of AI engines used by major TV brands and their implications for functionality. Sensors and AI Functionality (00:29:16) Discussion on the importance of sensors and microphones in smart TVs for AI functionality. Introduction to TV Technology Trends (00:30:29) Discussion on the shift in TV manufacturing and the rise of connected TV systems. Roku's Versatility in TV Market (00:31:27) Roku's functionality as a universal platform for various TV brands is highlighted. Operating Systems in TVs (00:31:45) Exploration of different operating systems like webOS, Tizen, and Roku in modern TVs. Consumer Awareness of TV Apps (00:33:03) Importance of understanding app availability on connected TVs for consumers. TiVo's Marketing Strategy (00:34:21) TiVo's new approach to marketing its operating system through partnerships with TV brands. Sharp's Return to the US Market (00:35:02) Discussion on Sharp's comeback in the TV market with a focus on its partnership with TiVo. Trends in TV Sizes (00:37:40) Analysis of the increasing size of TVs and the emerging market preferences. Direct View LEDs and Market Dynamics (00:39:25) Insight into the competition and advancements in direct view LED technology at CES. Challenges of Large TV Installations (00:42:47) Addressing the logistical challenges of installing large TVs in homes. Brightness Improvements in OLEDs (00:44:11) Overview of advancements in OLED technology and brightness enhancements from LG and Panasonic. Panasonic's OLED Innovations (00:47:03) Panasonic introduces a thermal cooling process for their OLED panels, performing well in high ambient light. Hisense's RGB Mini LED Announcement (00:48:01) Hisense surprises with RGB mini LEDs, enhancing brightness and contrast without traditional color filters. Hisense and TCL Brand Evolution (00:49:10) Discussion on Hisense and TCL's rise to first-tier brands, emphasizing their technological advancements. Trends in Display Technology (00:50:30) Exploration of non-reflective displays and advancements in gaming-focused frame rates. Samsung's Discrete RGB Micro LED (00:53:00) Samsung reveals a discrete RGB micro LED backlit set, promising enhanced brightness and contrast. Upcoming Display Technologies at Expo (00:54:01) Anticipation of new display technologies set to debut at the upcoming Expo. AI and Home Control Integration (00:55:16) Samsung promotes smart TV features that integrate AI for seamless home control. HDR10+ and Content Compatibility (00:57:46) HDR10+ press conference highlights its integration with Amazon Prime and other streaming services. Next Gen TV Developments (00:59:43) Next Gen TV advancements discussed, including cheaper dongles and the new zapper box for ATSC 3.0. Introduction to Marketing Strategies (01:01:58) Discussion on the importance of marketing in the tech industry and venue changes at CES. TV Innovations with Suction Cups (01:02:28) Overview of a TV with suction cups for mounting, highlighting its features and market presence. Trends in Monitor Sizes (01:03:40) Exploration of the trend towards larger, curved monitors for home and office use. Advancements in Audio Technology (01:05:30) Discussion on new audio technologies, including hearing aids and immersive audio experiences. Hearing Aid Innovations (01:06:54) Introduction of a new over-the-counter hearing aid with AI language translation features. Samsung's Eclipse Technology (01:08:16) Overview of Samsung's immersive audio technology and its implications for soundbars and TVs. Gyro-Sensing Soundbars (01:10:12) Description of a soundbar that adjusts audio output based on its mounting position. Audio Q's Dolby Atmos Decoder (01:12:04) Introduction of a product combining Dolby Atmos decoding with power line communication. Final Thoughts on Technology (01:13:31) Discussion on the importance of matching technology with client needs and standards in education. Wrap-Up and Future Events (01:14:45) Conclusion of the podcast and mention of upcoming events in Barcelona. Introduction to Press Releases (01:16:21) Discussion on the volume of press releases and their significance in staying informed about industry developments. Acronyms and Abbreviations Course (01:17:40) Overview of a course aimed at clarifying common acronyms used in the video technology industry. Event Dates Announcement (01:17:57) Mention of the upcoming event dates, February 4th to 6th, and the importance of continuous learning. Closing Remarks and Philosophy (01:18:19) Reflection on the importance of asking questions and keeping an open mind in discussions and learning. Final Thank You (01:18:54) Gratitude expressed to listeners, signaling the end of the podcast episode.
Welcome back to The Totally Wholesome (Not Dirty) Podcast! This week, Molly and Laura bring you an unfiltered mix of laughs, unexpected stories, and the highest vibes.We kick things off with retail adventures (or nightmares) as Laura shares her recent shopping struggles at Macy's, navigating everything from aloof sales associates to being treated like a theft risk. Molly chimes in with her own retail war stories and why customer service might be circling the drain.Then, it's onto neighborly chaos: naked gardeners, thong-clad exhibitionists, HOA shenanigans, and even a story of being accused of running a sex trafficking ring (seriously). If you've ever dealt with that neighbor, you'll relate.The episode wraps up with some lighter notes, including a heartfelt shoutout to patrons and a glimpse at exciting plans for the new podcast studio.
On this week's show we rundown the “Best of CES” as reported by the tech sites. We also read your emails and take a look at the week's news. News: Disney, Fox, Warner Bros. Discovery say Venu Sports won't launch DirecTV Launches ‘MySports' Streaming Package Other: Samsung Display CES 2025 showcase: All the cool tech we saw - SamMobile Star Wars Kid Star Wars kid Drunken Jedi Best of CES On this week's show we rundown the “Best of CES” as reported by the tech sites. Engadget LG OLED evo M5 - the company managed to further improve its most premium displays, adding the latest α (Alpha) 11 AI processor Gen2 to improve the look of lower-resolution content and power advanced features. Technics EAH-AZ100 earbuds ($300) - Technics' new Magnetic Fluid drivers have garnered a lot of headlines this week, but all you really need to know about the EAH-AZ100 earbuds is that the sound quality is massively improved. Powered by those new components, there's more clarity, detail and bass, all of which are upgrades from the already impressive AZ80 CNET LG G5 OLED TV - After seeing the picture quality, TV expert David Katzmaier singled this out as one of his favorite TVs of the show; he traditionally finds LG's OLED quality best-in-class (as do I for its monitors), and this year's is brighter with better contrast in ambient light. Xgimi Ascend - It's not the LG OLED rollable screen of your dreams, but the Ascend may be more within your grasp. It's a retractable, ambient light-rejecting screen with built-in speakers and an ultra short-throw projector that looks like a piece of furniture when the screen withdraws. TV tech guru Geoffrey Morrison has been an ultrashort throw skeptic, but thinks this pair may solve some of the issues he's had with them. There's no pricing yet for the screen (the projector is $2,700), but it's bound to be less than models like the LG. The Verge Awards at CES (Full List) Best TV Panasonic Z95B OLED - At CES 2025, it's the Panasonic Z95B OLED that I keep circling back to as my favorite. After a long hiatus from the US TV market, Panasonic is coming back for its crown. Like the G5, it features a new four-layer tandem OLED display that boosts brightness to new highs — this time without the micro-lens array technology that LG Display spent the last two years hyping. It also includes an impressive Dolby Atmos speaker array (tuned by Technics) that will rule out any need for a soundbar for many buyers. That audio hardware results in this being a thick TV by today's standards: Panasonic obviously favored nailing the picture and sound aspects over a thin design. And you know what? I'm here for it. Most no one asked for this, AI in TVs - AI is worming its way into everything, and at CES this year, it crawled into TVs and remotes. Naturally, that includes new sets from LG and Samsung, which are deploying AI to futz with your picture and sound settings and let you talk to a chatbot or analyze what's on your screen. Over at Hisense's “AI Your Life” booth, the company touted its AI Engine X that “optimizes every frame” with adjustments to color, brightness, and audio. Best smart home device Switchbot K20 Plus Pro - Switchbot's K20 Plus Pro is a robot vacuum that can have different devices strapped to its head using the company's modular “FusionPlatform.” As well as being able to deliver items around your home, it can have various SwitchBot products attached to it to perform tasks autonomously: purify your air, be a mobile home security camera, and carry your tablet around for you. They've even made an attachment to put a mini fridge on top. (So, yes, it can bring you a beer.) What intrigues me the most here is that its FusionPlatform is completely open; you can plug any device into its various power ports and customize this robot to do what you need. That's smart. Gizmodo's Best of CES 2025 Awards (Full List) Aurzen Zip Projector - The Aurzen Zip is the tiniest 720p projector I've ever seen. When folded, the $200 Zip is about the size of half an iPhone, making it the perfect on-the-go projector. The trifold projector can wirelessly mirror whatever is on your phone without a wifi connection. Two of the best features: it's MagSafe-compatible and has a 90-minute battery life. TCL QM6K TV - When it comes to TVs, bigger is always better—and it always comes with a higher price. But that's not the case with the TCL QM6K TV, with the 55-inch model costing $749 and the 98-inch version topping out at $3,499. Before you write the QM6K off as a no-frills budget brand, check out some of the specs. As a QD mini-LED device, the QM6K can give some of the pricier heavy hitters a run for their money in the color and brightness categories. In fact, the QM6K is 53% brighter than previous models and 10% more light efficient. Plus, it has a host of powerful tech onboard to make its case, including HDR10, HDR+, and Dolby Vision. You get integrated Onkyo speakers, which should produce solid audio. However, the screen's the star here, serving up captivating colors with deep blacks and sharp details. It's an absolute beauty of a TV that brings all the bells and whistles you'd expect from a premium television at a fraction of the price. Technics EAH-AZ100 Earbuds - It takes a lot to stand out in the crowded field of wireless earbuds, but Panasonic's new flagship Technics EAH-AZ100 manage to do just that. Panasonic claims its $300 earbuds, available now, can offer reference class HiFi audio without needing large wired cans, thanks to “magnetic fluid drivers.” The buds' sound quality was impressive, especially with the world snuffed-out with ANC mode turned on. The sound resolution and bass were especially surprising, even while surrounded by noisy throngs of CES goers.The brushed steel case design makes the buds feel as premium as their $300 price tag. XGIMI Ascend - The Xgimi Ascend is a gorgeous 2-in-1 prototype ALR (Ambient Light Rejection) projector screen with a powerful soundbar. The Ascend houses a 100-inch motorized floor-rising screen for an immersive home theater experience. We've seen rollup displays before, but none of them match the style of the Ascend. The screen is adjustable, allowing it to be partially lowered for ambient modes, like a cozy fireplace display or a music visualization. Though still a prototype, the Ascend has the potential to attract anyone who wants a pop-up movie theater without spending tens of thousands of dollars. AVS Forum Best of CES 2025 (Full List) Valerion VisonMaster Max Lifestyle Projector - This was easily one of the most anticipated booth visits for both us and our readers. When we tested the Valerion Pro2, we were impressed by its performance, but it lacked some key features you'd want for a fully dedicated home theater system. Enter the Valerion Max, the flagship model that was teased during the brand's Kickstarter campaign. It promised to deliver everything the Pro2 was missing, including a dynamic iris, and we finally got to see it in action. LG G5 OLED - It's easily one of the most impressive TVs we've seen at the show. Available in sizes ranging from 48 inches all the way up to 97 inches, the G5 is packed with features. All sizes (except the 48- and 97-inch models) include LG's Brightness Booster Ultimate. LG also gave the remote a much-needed makeover. it's now slimmer with fewer buttons, which is a welcome change. TCL QM6K Mini LED TV - TCL is taking a different approach this year with a phased rollout of their TV lineup, starting with the QM6K, the first model in their new Precise Dimming series. As an entry-level option, the QM6K brings a surprising amount to the table. It features 500 dimming zones, a 144Hz refresh rate (boosted to 288Hz with Game Accelerator), and TCL's AiPQ Pro Processor, carried over from last year's QM8 series. TCL 115QM7K - This one's a bit tricky. TCL is keeping most of the details about the QM7K under wraps for now, but from what we saw, it's shaping up to be a strong addition to their lineup. What we did find out is that the 115” model will have 25,000 dimming zones and 3000 nits of brightness. It's available in sizes up to 115 inches, this model expands on what was previously only offered in the QM8 series. The move could mean more affordable options for larger screens, which is always exciting. Onkyo Icon Series - The P-80 which is priced at $1,999, is a two-channel network preamplifier. It includes HDMI ARC, Dirac Live Room Correction, a phono output, and a fanless design to keep noise levels down. The build quality is sturdy as well, with a 5mm aluminum front panel and three-piece housing. The M-80 is also priced at $1,999, and is a two-channel power amplifier delivering 150 watts into 8 ohms or 200 watts into 4 ohms. It uses a Class AB 3-stage Inverted Darlington design, offering high current drive and low distortion. Focal DIVA Wireless Active Loudspeakers - The Focal DIVA speakers were announced about a month ago, and seeing them at CES 2025 confirmed they're as impressive as they sound on paper. These wireless active loudspeakers feature a 3-way bass reflex design and are surprisingly easy to set up. They support Bluetooth, AirPlay 2, Google Cast, and work with the Focal Naim app. Each speaker is equipped with its own DAC and DSP, delivering 75 watts to the midrange, 75 watts to the tweeter, and 125 watts to each bass driver. That's a total of 400 watts RMS powered by four Class AB amplifiers. At $39,999 a pair, the Divas aren't for everyone, but they began shipping during the show for those ready to invest in high-performance audio. LG CineBeam S Ultra Short Throw Projector - LG revealed their solution: the CineBeam S, an ultra short throw version of the projector. It retains all the features we liked from the CineBeam Q, including an RGB laser with native 4K resolution, 500 ANSI lumens of brightness, and auto screen adjustment. But the big update here is the ultra short throw design, making it much easier to fit into a variety of setups. Nexigo Aurora Pro MKII Ultra Short Throw Projector XGIMI Ascend 100-Inch ALR Motorized Screen Honorable Mentions Samsung Premiere 8K Ultra Short Throw Projector TCL's X11K Premium QD-OLED Mini LED TV
Follow-up: AirPod noises Gui Rambo & AirBuddy One of the noises is “the case battery is low” (via Zach) Also, more on status lights (via Tom French) Another noise is a calibration noise (via Ian Williamson) Knowledge base How to turn off charging sounds Look, ma! We’re famous! AirPod Noises (via Patch) TVs at CES 2025 Hisense’s 116UX with RGB mini-backlight Digital Trends coverage HDTVTest coverage DLSS History (via Hampus Jensen) Explanation (via flunkedflank) Digital Foundry explanation video Mac monitors Some foreign options (via Henry Chen) MacRumors thread Kuycon G27-X Another option (via Tim Ngwena) Asus ProArt Display 6K PA32QCV Quick look video DisplayHDR 600 spec Dynamic Island Live Alert (via Dan Engler)
Here's the Supporter-only Q&A from January 9th, 2025. All comments and questions are fielded through the supporter service Q&A page. Please consider supporting this channel via monthly support services, tips, or even just by using our affiliate links to purchase things you were already going to buy anyway, at no extra cost to you: https://www.retrorgb.com/support.html T-Shirts: https://retrorgb.link/tshirts Amazon Recommended List: http://retrorgb.link/amazon TIMESTAMPS (please assume all links are affiliate / paid links that pay RetroRGB a commission on each sale. Even if links are currently not affiliate, I may update them with one, should a partner list that item for sale in the future): 00:00 Welcome 01:01 Colecovision RGB Mod?: https://www.retrorgb.com/new-colecovision-rgb-mod-available-tms-rgb.html 04:51 LumaCode & OLED's 10:31 RGB SCART Cable Issues 14:16 BNC cable / RG6 suggestions 16:40 USB Capture Card Issues 18:57 Solder connections - MiSTer Wallpaper on a CRT 22:00 MiSTer Audio 26:00 Wii Component Cables: https://retrorgb.link/hdrwii 28:18 Everdrive N8 Issues: https://www.retrorgb.com/everdrive-n8-pro-firmware-v25-0107.html 30:11 HDMI to RGB: https://retrorgb.link/cheapdac & https://www.retrorgb.com/hd15-2-scart-europe-seller.html 32:38 Dreamcast Games RGB Compatibility Issues 35:12 OpenMVS: https://www.retrorgb.com/openmvs.html 38:32 Thank you!: https://www.retrorgb.com/support.html