Podcast appearances and mentions of mike gannon

Send us a Text Message (please include your email so we can respond!)Episode 64! We talk more about steroids in severe community acquired pneumonia with "Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial" published in Intensive Care Medicine April of 2025.Pubmed: https://pubmed.ncbi.nlm.nih.gov/40261382/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 63! We talk about intermediate risk PE in "Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis in the Management of Intermediate-Risk Pulmonary Embolism" by Jaber et al published in Circulation in February 2025. Then we talk about "Fibrinolysis for patients with intermediate-risk pulmonary embolism" by Meter et al in NEJM 2014.PEERLESS: https://pubmed.ncbi.nlm.nih.gov/39470698/PEITHO: https://pubmed.ncbi.nlm.nih.gov/24716681/PE Meta-analysis: https://pubmed.ncbi.nlm.nih.gov/24938564/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 62! We talk briefly about two of the analyses that dropped with the ISICEM conference and then talk in depth about SESAR or "Inhaled Sedation in Acute Respiratory Distress Syndrome" by Jabudon et al in JAMA 2025. Then was answer a question on sleep in the ICU. Eddie did misspeak when he said one of the dexmedetomidine articles was in Lancet Respiratory medicine, rather, it was published in eClinical Medicine part of the Lancet network.SESAR (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2831857SESAR (pubmed): https://pubmed.ncbi.nlm.nih.gov/40098564/OVISS (pubmed): https://pubmed.ncbi.nlm.nih.gov/40098600/Nocturnal dexmedetomidine (pubmed): https://pubmed.ncbi.nlm.nih.gov/29498534/Nocturnal dexmedetomidine cardiac surgery (pubmed): https://pubmed.ncbi.nlm.nih.gov/36590787/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 61! We talk about HFNC including extubation to HFNC in "Early weaning from invasive mechanical ventilation via high-flow nasal oxygen versus conventional weaning in patients with hypoxemic respiratory failure" by Ayyawar et al published in Critical Care Science. Then we talk about weaning HFNC from the "How I do it" series from CHEST.Auto-PEEP (NEJM): https://www.nejm.org/doi/full/10.1056/NEJM199307153290322Extubate to HFNC (pubmed): https://pubmed.ncbi.nlm.nih.gov/39879434/Extubate to HFNC (CCS): https://criticalcarescience.org/article/early-weaning-from-invasive-mechanical-ventilation-via-high-flow-nasal-oxygen-versus-conventional-weaning-in-patients-with-hypoxemic-respiratory-failure-a-prospective-randomized-controlled-study/Weaning HFNC (pubmed): https://pubmed.ncbi.nlm.nih.gov/39929280/Weaning HFNC (CHEST): https://journal.chestnet.org/article/S0012-3692(25)00155-2/abstractIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 60! We jump to SCCM where we talk about 2 late breakers - PROACTIVE or "Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation" by Downar et al and "Acetylsalicylic Acid Treatment in Patients With Sepsis and Septic Shock" by Almeida et al both published in CCM in 2025. PROACTIVE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39982178/PROACTIVE (CCM): https://pmc.ncbi.nlm.nih.gov/articles/PMC11801419/ASA in sepsis (pubmed): https://pubmed.ncbi.nlm.nih.gov/39982179/ASA in sepsis (CCM): https://journals.lww.com/ccmjournal/fulltext/2025/02000/acetylsalicylic_acid_treatment_in_patients_with.2.aspxIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 59! We finish our CCR down under coverage with TRAUMOX2 or "Early Restrictive vs Liberal Oxygen for Trauma Patients" published in JAMA by Arleth et al and then switch to SAHARA or "Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage" by English et al published in NEJM. We then frustrate Todd with questions from our mailbag, a good episode!TRAUMOX2 (pubmed): https://pubmed.ncbi.nlm.nih.gov/39657224/TRAUMOX2 (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2827980SAHARA (pubmed): https://pubmed.ncbi.nlm.nih.gov/39655786/SAHARA (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2410962If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 58! We talk about non-invasive oxygen support and RENOVATE or "High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure" published in JAMA December 2024 and presented at the CCR Down Under Conference. We supplement this by first talking about FLORALI or "High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure" published in NEJM May 2015RENOVATE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39657981/RENOVATE (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2828065FLORALI (pubmed): https://pubmed.ncbi.nlm.nih.gov/25981908/FLORALI (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa1503326If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 57! We were excited to have on this episode Dr. Adam Wright who is a PhD in Bioinformatics to discuss SCREEN or "Electronic Sepsis Screening Among Patients Admitted to Hospital Wards: A Stepped-Wedge Cluster Randomized Trial" published by Arabi et al in JAMA 2024 and presented at the CCR Down Under Conference. A long episode but a lot of good discussionSCREEN (pubmed): https://pubmed.ncbi.nlm.nih.gov/39658862/SCREEN (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2828069If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 56! In this episode we spend a few minutes talking about making decisions on ECMO initiation but spend most of the episode talking about ADAPT-Sepsis or "Biomarker-Guided Antibiotic Duration for Hospitalized PatientsWith Suspected Sepsis" published by Dark et al in JAMA 2024 and presented at the CCR Down Under Conference.ADAPT-Sepsis (pubmed): https://pubmed.ncbi.nlm.nih.gov/39652885/ADAPT-Sepsis (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2828036If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 55 and Happy New Year! In this episode we talk broad strokes about the CCR Down Under Conference and the trials that were presented, then Todd and Eddie go over a bunch of articles from the year 2024 that they didn't have time to go over or want to re-emphasize for whatever reason. Big show and we hope you enjoy!TIGHT K: https://pubmed.ncbi.nlm.nih.gov/39215972/PROPHY VAP: https://pubmed.ncbi.nlm.nih.gov/38262428/REVISE: https://pubmed.ncbi.nlm.nih.gov/38875111/Point (withdrawal of ECMO): https://pubmed.ncbi.nlm.nih.gov/39663030/Counterpoint: https://pubmed.ncbi.nlm.nih.gov/39663031/DanGer SHOCK: https://pubmed.ncbi.nlm.nih.gov/38587239/Intubation in physiologic difficult airway guidelines: https://pubmed.ncbi.nlm.nih.gov/39162823/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 54! In this episode we talk about antibiotic duration in bacteremia (BALANCE) and also antibiotic duration in Pseudomonas Ventilator associated pneumonia (iDIAPASON). BALANCE (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa2404991BALANCE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39565030/iDIAPASON (ICM): https://link.springer.com/article/10.1007/s00134-022-06690-5iDIAPASON (pubmed): https://pubmed.ncbi.nlm.nih.gov/35552788/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 53! In this episode we talk about access in patients with out of hospital cardiac arrest. Both articles are similar so we talk in depth about IVIO and then bringing PARAMEDIC-3 to round out our discussion. A good acronym discussion too, don't miss it!IVIO (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2407616IVIO (pubmed): https://pubmed.ncbi.nlm.nih.gov/39480221/PARAMEDIC-3 (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa2407780PARAMEDIC-3 (pubmed): https://pubmed.ncbi.nlm.nih.gov/39480216/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 52! In this episode we talk about fevers in acute neurologic injury and double that up with talking about low tidal volume ventilation in patients with neurologic injuryINTREPID (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2824088INTREPID (pubmed): https://pubmed.ncbi.nlm.nih.gov/39320879/PROLABI (Blue): https://www.atsjournals.org/doi/full/10.1164/rccm.202402-0375OCPROLABI (pubmed): https://pubmed.ncbi.nlm.nih.gov/39288368/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)We are (were) LIVE at ACNP Critical Care Bootcamp 2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about the NONSEDA trial or "Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients" by Olsen et al published in the New England Journal of Medicine February 2020NONSEDA (pubmed): https://pubmed.ncbi.nlm.nih.gov/32068366/NONSEDA (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa1906759If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 50! In this episode we talk about SBT frequency and "Frequency of Screening and Spontaneous Breathing Trial Techniques" by Burns et al from JAMA 2024 that was released with the ESICM conference. In our second segment, instead of another trial we talk a little bit about the IV fluid shortage happening in the United States.FAST (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2824928FAST (pubmed): https://pubmed.ncbi.nlm.nih.gov/39382222/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)We are LIVE at CHEST2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about a few articles that were recently published in CHEST - "Prophylactic Minocycline for Delirium in Critically Ill Patients: A Randomized Controlled Trial" published by Dal-Pizzol et al and then "Comparative Effectiveness of Amiodarone and Lidocaine for the Treatment of In-Hospital Cardiac Arrest" by Wagner et al.We then touch briefly on some articles being presented later at the conference which we might cover soon (stay tuned)!Minocycline for Delirium (pubmed): https://pubmed.ncbi.nlm.nih.gov/38043911/Minocycline for Delirium (CHEST): https://journal.chestnet.org/article/S0012-3692(23)05833-6/abstractAmio vs Lido (pubmed): https://pubmed.ncbi.nlm.nih.gov/36332663/Amio vs lido (CHEST): https://journal.chestnet.org/article/S0012-3692(22)04039-9/abstractIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 48! In this episode we talk about the long term effects of ICU visitation policies on families. Long Term Outcomes of Visitation (pubmed): https://pubmed.ncbi.nlm.nih.gov/39172240/Long Term Outcomes of Visitation (ICM): https://link.springer.com/article/10.1007/s00134-024-07577-3Outcomes of Visitation (pubmed): https://pubmed.ncbi.nlm.nih.gov/31310297/Outcomes of Visitation (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2738289If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Laura talks to Mike Gannon from That Pond Place about the benefits and challenges of having a retail operation.

Send us a Text Message (please include your email so we can respond!)Episode 47! In this episode we talk about a prospective observational study examining cognitive motor dissociation by Bodien et al published in the New England Journal of Medicine and then we pair that talking about the guidelines for death by neurologic criteria published in SCCM! An episode of somber but important topics!Cognitive Motor Dissociation (pubmed): https://pubmed.ncbi.nlm.nih.gov/39141852/Cognitive Motor Dissociation (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2400645 DBNC Guidelines (pubmed): https://pubmed.ncbi.nlm.nih.gov/37921516/DBNC Guidelines (CCM): https://journals.lww.com/ccmjournal/fulltext/2024/03000/the_2023_american_academy_of_neurology,_american.3.aspx If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 46! In this episode we talk about thrombolytic windows in acute ischemic stroke from TIMELESS published by Albers et al published in the New England Journal of Medicine and then we talk about ANDROMEDA shock and serial lactates published by Hernandez et al!TIMELESS (pubmed): https://pubmed.ncbi.nlm.nih.gov/38329148/TIMELESS (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2310392ANDROMEDA-Shock (pubmed):https://pubmed.ncbi.nlm.nih.gov/30772908/ANDROMEDA-Shock (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2724361If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

NY Times Bestselling author Michael Ledwidge joins BOOKSTORM to dive down deep into his latest thriller! While off the grid, Mike Gannon, former Navy Seal and NYPD Detective, runs into an old girlfriend who is investigating a missing student from an elite college. Enter a whistleblower, some dangerous men, and that's when the lights go out! We talk about being that "one" voice willing to stand up for justice. Are college students vulnerable to manipulation and making wrong choices that last a lifetime? Have we become a society who blindly follows authority without question? Danger, high stakes and survival ignite Mike Gannon's greatest strengths! Don't miss this great read! Survival at all costs!You can find more of your favorite bestselling authors at BOOKSTORM Podcast! We're also on Instagram, TikTok, Facebook, and YouTube!

Send us a Text Message (please include your email so we can respond!)Episode 45! In this episode we talk about sepsis bundles and the 1-BED trial by Fruend et al and discuss the stress ulcer prophylaxis guidelines just published in SCCM!1-BED (pubmed): https://pubmed.ncbi.nlm.nih.gov/38913098/SUP Guidelines: https://www.sccm.org/Clinical-Resources/Guidelines/Guidelines/SCCM-ASHP-Guideline-Prevention-of-UGIBIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)We were honored to be joined by Joanna Stollings (and honestly we needed someone to keep us grounded) to talk about BLING3 or "Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis" published in JAMA by Dulhunty et al and also released with the CCR24 conference.pubmed: https://pubmed.ncbi.nlm.nih.gov/38864155/JAMA:  https://jamanetwork.com/journals/jama/fullarticle/2819971If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 43! In this episode come close to finishing our dedicated discussion of the CCR24 trials talking about transfusion targets in TBI (HEMOTION) and dapagliflozin in critical illness (DEFENDER)!HEMOTION: https://www.nejm.org/doi/full/10.1056/NEJMoa2404360HEMOTION (pubmed): https://pubmed.ncbi.nlm.nih.gov/38869931/DEFENDER: https://jamanetwork.com/journals/jama/fullarticle/2820242DEFENDER (pubmed): https://pubmed.ncbi.nlm.nih.gov/38873723/Bootcamp Details:Vanderbilt University Medical Center is hosting its annual Critical Care ACNP/PA Bootcamp. This multi-specialty conference is designed for nurse practitioners and physician assistants working in critical care. The program, now in its thirteenth year, features a mix of lectures, roundtable discussions, expert Q&A sessions and networking opportunities aimed at both new and experienced providers. #CCBootcamp2024Dates: September 4-5, 2024 from 08:00 AM - 3:30 PM each dayTarget Audience: This course is designed for nurse practitioners and physician assistants working in critical care.Location: Loews Vanderbilt Hotel located at 2100 West End Ave, Nashville, TN Registration: https://www.eventbrite.com/e/vumc-critical-care-acnppa-bootcamp-2024-tickets-830345073467?utm-campaign=social&utm-content=attendeeshare&utm-medium=discovery&utm-term=listing&utm-source=cp&aff=ebdsshcopyurl More Info: https://www.vumc.org/advanced-practice-critical-careIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message (please include your email so we can respond!)Episode 42! In this episode we foray into weight lifting and body building as we talked about amino acids for kidney protection after cardiac surgery (PROTECTION) and cycling in addition to PT in mechanically ventilated adults (CYCLE). We also feature our first real ad for the Critical Care ACNP/PA Bootcamp! Details below! Bagging vs Ventilator During Cardiac Arrest: https://journal.chestnet.org/article/S0012-3692(24)00248-4/abstractPROTECTION: https://www.nejm.org/doi/full/10.1056/NEJMoa2403769PROTECTION (pubmed): https://pubmed.ncbi.nlm.nih.gov/38865168/CYCLE: https://evidence.nejm.org/doi/10.1056/EVIDoa2400137CYCLE (pubmed): https://pubmed.ncbi.nlm.nih.gov/38865147/Bootcamp Details:Vanderbilt University Medical Center is hosting its annual Critical Care ACNP/PA Bootcamp. This multi-specialty conference is designed for nurse practitioners and physician assistants working in critical care. The program, now in its thirteenth year, features a mix of lectures, roundtable discussions, expert Q&A sessions and networking opportunities aimed at both new and experienced providers. #CCBootcamp2024Dates: September 4-5, 2024 from 08:00 AM - 3:30 PM each dayTarget Audience: This course is designed for nurse practitioners and physician assistants working in critical care.Location: Loews Vanderbilt Hotel located at 2100 West End Ave, Nashville, TN Registration: https://www.eventbrite.com/e/vumc-critical-care-acnppa-bootcamp-2024-tickets-830345073467?utm-campaign=social&utm-content=attendeeshare&utm-medium=discovery&utm-term=listing&utm-source=cp&aff=ebdsshcopyurl More Info: https://www.vumc.org/advanced-practice-critical-careIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message.Episode 41! We continue our CCR24 recap with a brief overview and thoughts on the conference as a whole and then dive into REVISE or  "Stress Ulcer Prophylaxis duringInvasive Mechanical Ventilation" published by Cook et al in NEJM June 2024. Not the sexiest of all the topics but important nonetheless (and we will get to the others soon!)REVISE: https://pubmed.ncbi.nlm.nih.gov/38875111/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Send us a Text Message.Episode 40! In this special episode releasing at the conclusion of the PREOXI presentation at the Critical Care Reviews 2024 conference in Belfast, Ireland - we discuss the recently published PREOXI trial evaluating NIV vs facemask as pre-oxygenation for emergent endotracheal intubation. Kevin Gibbs, the first author and presenter at the conference, is our special guest.  Stay tuned for our review of some of the other results from the conference!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 39! In this episode we talk about steroids in septic shock from community acquired pneumonia - a secondary from the APROCCHSS trial. We then dive into our mailbag to talk about a couple of topics we've been asked questions about and address them in a more broad sense. A pseudo-mailbag but with real answersAPROCCHSS-CAP: https://pubmed.ncbi.nlm.nih.gov/38310918/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

We're live from ATS! We decide to format our episode after the NEJM/JAMA/ATS combined session and talk about the articles presented there. Some of them we've talked about before but provide new insights from listeners and questions from the audience. Some of them are new and we provide our thoughts from the presentations (not enough time to fully read the articles)The one article we skip is ASTER that was published in JAMA by Ware et al during the conference. We want to spend a little more time on that one (and potentially have an author as a guest)! Stay tuned!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 37! In this episode we talk about glycemic control in the ICU. We liked the flipped script and so we're again going old article first. NICE-SUGAR or "Intensive versus conventional glucose control in critically ill patients" was published in NEJM 2009 and then we talk about TGC-Fast or "Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU" published NEJM September of 2023 NICE SUGAR: https://pubmed.ncbi.nlm.nih.gov/19318384/TGC-Fast: https://pubmed.ncbi.nlm.nih.gov/37754283/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 36! In this episode we talk about tranexamic acid in GI bleeds. We flip the script a little bit and talk about our OLD article first, HALT-IT or "Tranexamic acid in upper gastrointestinal bleed in patients with cirrhosis: A randomized controlled trial" published in Lancet in 2020. This sets the stage for our new trial "Tranexamic acid in upper gastrointestinal bleed in patients with cirrhosis" published in Kumar et al in Hepatology (a new journal for us!)HALT-IT: https://pubmed.ncbi.nlm.nih.gov/32563378/TXA and cirrhosis: https://pubmed.ncbi.nlm.nih.gov/38441903/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 35! In this episode we talk about extubation practices with "Effect of aggressive vs conservative screening and confirmatory test on time to extubation among patients at low or intermediate risk: a randomized clinical trial" published in Intensive Care Medicine by Hernandez et al. We then talk about an observation study by Zarrabian et al published in the Blue Journal "Liberation from Invasive Mechanical Ventilation with Continued Receipt of Vasopressor Infusions".SPEED UP: https://pubmed.ncbi.nlm.nih.gov/38353714/Extubation on Pressors: https://pubmed.ncbi.nlm.nih.gov/35107416/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 34! In this episode we talk about oxygen targets! Specifically we go over the two oxygen target analyses that were published simultaneously with ISICEM. We spend most of our time with HOT-COVID published by Nielson et al and then dip a little into individualized treatment effects of oxygen targets published by Buell et al - both published in JAMA March 2024. The latter is a complex topic and we hit some of the high points but please reach out to us if you want a more in depth discussion!HOT-COVID: https://pubmed.ncbi.nlm.nih.gov/38501214/Individualized Treatment Effects: https://pubmed.ncbi.nlm.nih.gov/38501205/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 33! In this episode we are excited to be joined by Eddy Fan and Whitney Gannon, two extraordinary ECMO researchers to talk about VENT-AVOID or " Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During Exacerbations of Chronic Obstructive Pulmonary Disease" published March 2024 by Duggal et al in the ATS Blue Journal.VENT-AVOID: https://pubmed.ncbi.nlm.nih.gov/38261630/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 32! We got a lot of feedback on our last episode so we decided to address it in a full episode! A lot of listeners asked us about vasopressors specifically vasopressin and angiotensin-2 so we talk about VASST, VANISH, and ATHOS-3. It is a full episode but a good one!VASST: https://pubmed.ncbi.nlm.nih.gov/18305265/VANISH: https://pubmed.ncbi.nlm.nih.gov/27483065/ATHOS-3: https://pubmed.ncbi.nlm.nih.gov/28528561/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 31! This episode we talk first about invasive vs non-invasive blood pressures from an observational paper titled "Accuracy of Noninvasive Blood Pressure Monitoring in Critically Ill Adults" published in journal of Intensive Care Medicine by Haber et al and then for our old trial we further the discussion of blood pressure by talking about the 65 trial!Non-invasive vs invasive blood pressure: https://pubmed.ncbi.nlm.nih.gov/38215002/65 Trial: https://pubmed.ncbi.nlm.nih.gov/32049269/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 30! This episode is a little different. We recap the SCCM conference first. THEN we go into PROPHY-VAP or "Ceftriaxone to prevent early ventilator-associated pneumonia in patients with acute brain injury" published January 2024 by Professor Dahyot-Fizelier in Lancet Respiratory Medicine. Then we dive into our long neglected mailbag to review listener questions about MINT, intubation timing, ACORN, and all the steroids in ARDS talkPROPHY-VAP: https://pubmed.ncbi.nlm.nih.gov/38262428/SCCM Steroid guidelines: https://pubmed.ncbi.nlm.nih.gov/38240492/Counter-Point should we use steroids in ARDS: https://pubmed.ncbi.nlm.nih.gov/33422201/sRAGE in NIV and HFNC: https://pubmed.ncbi.nlm.nih.gov/38250011/Anaerobes in Aspiration: https://pubmed.ncbi.nlm.nih.gov/37250794/Anaerobes in Gut: https://pubmed.ncbi.nlm.nih.gov/36229047/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 29! We stray a little bit from our new and old article structure to talk about two recently published but slightly different ARDS recommendations from ATS and ESCIM. We compare and contrast them and give our takes on the data and evidence.Thanks to everyone who emails in and gives feedback, we will do our mail bag next episode!ATS Guidelines: https://pubmed.ncbi.nlm.nih.gov/38032683/ESICM guidelines: https://pubmed.ncbi.nlm.nih.gov/37326646/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 28! In this episodes we talk about ECMO! PRONECMO evaluated the effect of prone positioning on patients already on ECMO by Schmidt et al in JAMA December 2023 and then EOLIA by Combes et al in NEJM 2018 which is our old article which randomized patients to ECMO or not. Great discussion here!PRONECMO: https://pubmed.ncbi.nlm.nih.gov/38038395/EOLIA: https://pubmed.ncbi.nlm.nih.gov/29791822/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 27! In this episodes we sit down to talk all about the "when" to intubate a patient centered around acute poisoning in the NICO trial or "Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning: A Randomized Clinical Trial" published by Freud et al in JAMA November 2023. We ended up talk a lot about that so we cut our old article a little bit short and discuss a couple of JAMA articles about definitive airways in out of hospital cardiac arrestNICO: https://pubmed.ncbi.nlm.nih.gov/38019968/PART: https://pubmed.ncbi.nlm.nih.gov/30167699/Prehospital advanced airway: https://pubmed.ncbi.nlm.nih.gov/23321764/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

This was easily our most requested article to discuss and for good reason - Eddie and Todd recently published the ACORN trial or "Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection" in JAMA October 2023. We recognize our bias as the first and last authors on the paper so we wanted to get some other smart people in the studio to balance us out so we partnered with Furf and Monty of PulmPEEPs for this episode. It is simul-dropping on their feed as well. Thank you to them for a great episode and the opportunity to talk about our trial!ACORN: https://pubmed.ncbi.nlm.nih.gov/37837651/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 25! In this episode we talk about the MINT trial or "Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia" published in NEJM November 2023 by Carson et al. We supplement this with a recent observational cohort study that gives Todd anxiety titled "Intracerebral Hemorrhage Among Blood Donors and Their Transfusion Recipients" by Zhao et al in JAMA September 2023.MINT: https://pubmed.ncbi.nlm.nih.gov/37952133/TRACS: https://pubmed.ncbi.nlm.nih.gov/20940381/REALITY: https://pubmed.ncbi.nlm.nih.gov/33560322/ICH in transfusions: https://pubmed.ncbi.nlm.nih.gov/37698562/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 24! Three trials about COVID were published with ESICM which we talk about all three here. COVID has been decreasing in prevalence in our ICU at least so we anchor our discussion around what we can learn from these trials about ARDS in general or what we can carry forward to future pandemics compared to our typical "Are we using this in our practice".Simvastatin: https://pubmed.ncbi.nlm.nih.gov/37888913/Vitamin C: https://pubmed.ncbi.nlm.nih.gov/37877585/Convalescent Plasma: https://pubmed.ncbi.nlm.nih.gov/37889107/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 23! We spend a little bit of time talking about our recent conference related travel and food experience but dive into our coverage of the trials that released with ESICM including "Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia" by Ehrmann et al published in NEJM and "Landiolol and Organ Failure in Patients With Septic Shock" by Whitehouse et al in JAMA, both October 2023AMIKINHAL: https://pubmed.ncbi.nlm.nih.gov/37888914/STRESS-L: https://pubmed.ncbi.nlm.nih.gov/37877587/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 22! In this episode we talk about "Peripheral Administration of Norepinephrine: A Prospective Observational Study" published August 2023 by Yerke et al in CHEST. For our old article we talk about "Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit (MIDAS)" by Santer et al published October 2020 by Santer et al.No mailbag this time, we recorded this episode ahead of time to account for travel schedules.Peripheral Pressors: https://pubmed.ncbi.nlm.nih.gov/37611862/MIDAS: https://pubmed.ncbi.nlm.nih.gov/32885276/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Live show? Thank you so much to the organizers of the ACNP/PA Critical Care Bootcamp who invited us to do a live episode of the show! We talked about the AKIKI2 trial "Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury" by Gaudry et al in Lancet 2021.AKIKI2: https://pubmed.ncbi.nlm.nih.gov/33812488/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 21! In this episode we talk about "Extracorporeal Life Support in Infarct-Related Cardiogenic Shock" published August 2023 by Thiele et al in NEJM. Then we dive into our neglected mail bad to try to answer some listener questions.ECLS-SHOCK: https://pubmed.ncbi.nlm.nih.gov/37634145/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 20! In this episode we talk about "Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation" published October 2022 by the ANZICS group in JAMA. We have the first author and senior authors on the accompanying systematic review and meta-analysis, Naomi Hammond and Anthony Delany, all the way from Australia (!) on with us to talk to us about the trial.SuDDICU: https://pubmed.ncbi.nlm.nih.gov/36286097/Meta-analysis: https://pubmed.ncbi.nlm.nih.gov/36286098/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 19! In this episode we talk about "Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation" published November 2022 by Semler et al in the New England Journal of Medicine. We have the first author, Matt Semler, on with us to talk to us about the trial and his improv comedy claim to fame.PILOT: https://pubmed.ncbi.nlm.nih.gov/36278971/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Episode 18! In this episode we talk about "Early adjunctive methylene blue in patients with septic shock: a randomized controlled trial" published March 2023 by Ibarra-Estrada et al in Critical Care. We made a planning mistake so no old article today so we left it short!Methylene blue: https://pubmed.ncbi.nlm.nih.gov/36915146/Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!