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Send us a Text Message (please include your email so we can respond!)Episode 66! Today we talk about Acute Chest Syndrome in Sickle Cell Disease with one of our favorite hematologists, Benjamin Tillman! We base our discussion around the TASC trial or "Comparison of Prophylactic and Therapeutic Doses of Anticoagulation for Acute Chest Syndrome in Sickle Cell Disease" published by Dessap et al in AJRCCM April of 2025.Pubmed: https://pubmed.ncbi.nlm.nih.gov/40209087/AJRCCM: https://www.atsjournals.org/doi/10.1164/rccm.202409-1727OCIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
At the end of April 2025, we released an episode summarizing the ERAS update for 2025. In that episode/update, we summarized the data on extended spectrum prophylactic antibiotics at cesarean section in patients living with obesity. The ERAS protocol recognized the value of oral cephalexin and metronidazole for 48 hours in patients with obesity who receive single agent Cephalosporin prophylaxis preop. Now, a new (RCT) publication soon to be released in the Green Journal, evaluates whether using dual agent pre-op prophylaxis (ancef and zithromax) together with post op oral cephalexin and metronidazole has benefit in reduction of SSI composite risk. Does this help? When is too much prophylactic antibiotics, just too much? Listen in for details.
Antibody-drug conjugates (ADCs) are novel therapeutic agents designed to target specific tumor markers with potent anticancer drugs. The Association of Cancer Care Centers (ACCC) is dedicated to providing up-to-date information on ADC treatment management. In this episode, CANCER BUZZ speaks with Nancy Mallett, a patient advocate, to discuss the patient's perspective and experience receiving treatment for gynecologic cancers, particularly with ADCs such as mirvetuximab soravtansine-gynx. “[Providers] giving me the information and allowing us to decide together, instead of just telling me, makes me feel more cared about and that I'm not just a number, I'm a person. They care about what I think, and look at my life and what it can do for me.” – Nancy Mallett Nancy Mallett Patient Advocate Resources: FDA Approval Summary: Mirvetuximab soravtansine-gynx for FRα-positive, Platinum-Resistant Ovarian Cancer - https://bit.ly/4is00nD Society of Gynecologic Oncology (SGO): Gynecologic Cancer Resources for Patients and Their Families - https://bit.ly/4jpYaoP ASCO: Antibody-Drug Conjugates in Gynecologic Cancer - https://bit.ly/42GP5k8 Society of Gynecologic Oncology Journal Club: The ABCs of ADCs (Antibody drug Conjugates) - https://bit.ly/42U2962 Antibody-Drug Conjugates in Gynecologic Cancers - https://bit.ly/4cLYECZ Funder Statement This program is supported by AbbVie.
Bryan and Peter are back together and they cover all of their favorite topics from selling vintage toys to traveling in Japan to old sneakers. They also get a VOICE MEMO from James McCabe who is nearing the end of his training for the Boston Marathon, but needs new motivation. And then Bryan and Peter finally make some decisions about making decisions about the big run on June 21st.
Lisa Noghuchi of Jhpeigo (Johns Hopkins University) and Nyaradzo Mgodi (University of Zimbabwe) join Peter Hayward to discuss the MTN-043 study assessing safety and drug exposure of the dapivirine ring in breastfeeding women.Read the full article:https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(24)00306-0?dgcid=buzzsprout_icw_podcast_generic_lanhivContinue this conversation on social!Follow us today at...https://twitter.com/thelancethttps://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
Editor’s Choice: Primary prevention of post-molar gestational trophoblastic neoplasia in high-risk complete hydatidiform mole: A single-dose prophylactic actinomycin D, associated with uterine evacuation - a long retrospective cohort study Editorial: Prevention of Gestational Trophoblastic Neoplasia with Actinomycin -D at the time of evacuation: A Matter of Routine Practice or Reserve for Special Circumstances?
Dreams of Consciousness Podcast Episode 361 features an interview with Alexander Jones of Undeath. My thanks again to Alexander for speaking with me, and to you for listening. Music In This Episode: "Rise from the Grave" taken from the album It's Time...To Rise From the Grave "Lord Of The Grave" taken from the album Lesions Of A Different Kind "Cramped Caskets (Necrology)" "Disattachment of a Prophylactic in the Brain" taken from the album More Insane Thanks for listening! I hope you enjoyed listening to this as much as I enjoyed making it! Interviews, reviews, and more at www.dreamsofconsciousness.com
Commentary by Dr. Megan Tesch.
TIL that 4 AM is way too goddamn early to record a podcast. Apologies if I'm more chipper than usual, that's probably the coffee talking. Had some great e-mails this show. You should keep the streak alive and mouth off with your fingers at podcast@searls.co. Savor this version, folks. Gonna be at least a few weeks until you'll have another one. International Driver's Permit Don't be that guy. Don't drive a go-kart in downtown Tokyo Watch my final talk, The Empowered Programmer (Justin's Version) I have to pay for a search engine now, wtf macOS Sequoia iPhone Mirroring is cool Aaron's puns, ranked The Nintendo Music app is rad Fresca is extremely-flavored seltzer water Don't disable "Prioritize Faster Shooting" Google has a thumb on the scale Apple is buying Pixelmator Mass Effect is coming to Amazon Prime Video Pour one out for the You've Got Mail guy Notepad.exe is AI now LLMs may be reaching a point of diminishing returns Newest member of the badass scientist of the month club How to undervolt your GPU Like a Dragon: Yakuza Galileo G8 controller
Researchers Look at Prophylactic Antibiotics for the Prevention of Prosthetic Joint Infections By Spring Hatfield, RDH, BSPH Original article published on Today's RDH: https://www.todaysrdh.com/researchers-look-at-prophylactic-antibiotics-for-the-prevention-of-prosthetic-joint-infections/ Need CE? Start earning CE credits today at https://rdh.tv/ce Get daily dental hygiene articles at https://www.todaysrdh.com Follow Today's RDH on Facebook: https://www.facebook.com/TodaysRDH/ Follow Kara RDH on Facebook: https://www.facebook.com/DentalHygieneKaraRDH/ Follow Kara RDH on Instagram: https://www.instagram.com/kara_rdh/
Linda Petticrew's battle with breast cancer at 34, and her daughter Rachel Evans' decision to have a prophylactic mastectomy at 25, reveal a narrative of resilience and proactive health decisions. Diagnosed with the BRCA1 gene, Rachel chose surgery as a precaution, influenced by her mother's experience with the disease. Their story highlights the importance of genetic testing and the strength found in family support. Key Questions Answered What is the relationship between Linda Petticrew and Rachel Evans? Linda underwent mastectomies due to being diagnosed with breast cancer, while Rachel had a prophylactic mastectomy due to testing positive for the BRCA1 gene. At what ages were Linda and Rachel when they had their mastectomies? Did anyone else in Linda's family have breast cancer prior to her diagnosis? How did Linda feel when she found out Rachel tested positive for the BRCA gene? How did the recovery experiences differ between Linda and Rachel? How did Rachel share her decision to undergo a prophylactic mastectomy and its implications? Timestamped Overview 00:00 Mother and daughter discuss their mastectomies experiences.05:16 Grateful for urging timely, crucial conversation, answers.08:32 Thankful for company benefits during hospital stay.11:32 Posted about BRCA gene on Instagram: questions followed.15:26 Shell supportive during cancer, knee replacement recovery.19:18 Mobile services provided for convenient health testing.21:40 Executive assistants supporting education, philanthropy in Houston.26:44 Podcast about breast health by The Rose. Support The Rose HERE. Subscribe to Let's Talk About Your Breasts on Apple Podcasts, Spotify, iHeart, and wherever you get your podcasts.See omnystudio.com/listener for privacy information.
In this second instalment Jonathan is joined by Sunil Gupta, Consultant Haematologist and haemato-oncologist based at Lewisham and Greenwich NHS Trust, UK, to delve further into prophylactic anticoagulation in APML patients with COVID-19 and, anthracycline toxicity, and new drug appraisals for NICE. Timestamps: (00:00)-Introduction (00:25)-Prophylactic anticoagulation in patients with APML (03:26)-Anthracyclin as the cornerstone of chemotherapy (08:18)-Developing drugs for cancer (16:52)-New innovations in haematology (20:00)-Sunil's three wishes
TWiV reviews Marburg virus outbreak in Rwanda, cryo-EM based discovery of a parvovirus causing black wasting disease in farmed beetles, and a mosaic nanoparticle experimental vaccine that elicits cross-reactive sarbecovirus responses in pre-vaccinated animals. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Marburg virus disease, Rwanda (WHO) Suspected German Marburg case tests negative (Politico) Cryo-EM discovery of insect parvovirus (Cell) Mosaic sarbecovirus nanoparticle experimental vaccine (Cell) Letters read on TWiV 1157 Timestamps by Jolene. Thanks! Weekly Picks Brianne – ASM Lesson Plans Alan – A City on Mars, and this blog by a ham radio operator hit by Hurricane Helene Vincent – How to Win A Nobel Prize Listener Pick Laura – Science of Public Communication (original article) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
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Ovarian cancer, often referred to as the "silent killer," has been misunderstood for years. In this episode of 20-Minute Health Talk, Jill Whyte, MD, a leading gynecologic oncologist at Northwell Health, demystifies the subtle symptoms that frequently go unnoticed and emphasizes the critical role of early diagnosis — particularly for those at the highest risk of ovarian cancer. She also explores the latest advances in treatment, from targeted therapies like PARP inhibitors, to minimally invasive surgeries and new preventive strategies. Prophylactic fallopian tube removal has been the standard of care for those at the highest risk but is now being used in certain situations for women at average risk. During Ovarian Cancer Awareness Month in September, Dr. Whyte implores women everywhere to educate themselves and their family and friends to help reduce the impact of this deadly disease. Chapters: 01:15 - Ovarian cancer prevalence, trends 01:54 - Ovarian cancer symptoms 04:20 - PARP inhibitors and other ovarian cancer treatments 06:00 - Ovarian cancer risk factors 06:38 - Surgery types 08:38 - Strategies to prevent ovarian cancer 10:30 - The role of the fallopian tubes 14:50 - Catching ovarian cancer early 15:17 - Genetic testing 16:12 - Northwell's Cancer Institute 17:15 - Patient navigators Watch episodes of 20-Minute Health Talk on YouTube. For information on our more than 100 medical specialties, visit Northwell.edu and follow us @NorthwellHealth on Facebook, Instagram, X and LinkedIn. Interested in a career at Northwell Health? Visit http://bit.ly/2Z7iHFL and explore our many opportunities. Facebook – / northwellhealth Instagram - / northwellhealth X - https://www.x.com/northwellhealth LinkedIn - https://www.linkedin/northwellhealth
Not seeing improvement on your current candida protocol? You may find better results through natural remedies! In this episode, I'll name the most effective herbal supplements, recommended dosages, and the best lifestyle habits that will help to heal candida overgrowth. Watch now! Candida Diet Handout: https://drruscio.com/wp-content/uploads/2024/05/Candida-Diet-Handout-2024.pdf
Prior to initiating the war of conquest of the land of Canaan, the nation did the prudent thing: they undertook a reconnaissance mission to scout out the enemy defenses. Moshe selected 12 righteous men, one from each tribe, to traverse the land and inspect it from the inside. The result was a catastrophic disaster: the […]
Prior to initiating the war of conquest of the land of Canaan, the nation did the prudent thing: they undertook a reconnaissance mission to scout out the enemy defenses. Moshe selected 12 righteous men, one from each tribe, to traverse the land and inspect it from the inside. The result was a catastrophic disaster: the scouts brought a devastating report about the land, prompting the people to lose faith in God and in the prospect of entering Canaan. In this Parsha podcast, we explore three elements of the Parsha: the first segment orients around one of the descriptions of the land offered by the scouts. The second and third segments relate to the end of the Parsha: The execution of a person who was gathering twigs on Shabbos, and the commandment to tie fringes to corners of our garments.– – – – – – – – – – – – – – – – – – – – – –DONATE to TORCH: Please consider supporting the podcasts by making a donation to help fund our Jewish outreach and educational efforts at https://www.torchweb.org/support.php. Thank you!– – – – – – – – – – – – – – – – – – – – – –Email me with questions, comments, and feedback: rabbiwolbe@gmail.com– – – – – – – – – – – – – – – – – – – – – –SUBSCRIBE to my Newsletterrabbiwolbe.com/newsletter– – – – – – – – – – – – – – – – – – – – – –SUBSCRIBE to Rabbi Yaakov Wolbe's PodcastsThe Parsha PodcastThe Jewish History PodcastThe Mitzvah Podcast This Jewish LifeThe Ethics PodcastTORAH 101 ★ Support this podcast ★
Attacks on reproductive freedom! Attacks on queer & trans folk! Attacks on books! It’s enough to make you want to scream into the void. Thankfully, there’s an alternative to screaming into the void that you might not have heard of yet—and solid action you can take. Let us introduce you to
Today on the Daily Bespoke podcast, we see if Jerry completed his 7-sharp "challenge" that was issued to him on yesterday's episode...See omnystudio.com/listener for privacy information.
Expert Approach to Hereditary Gastrointestinal Cancers presented by CGA-IGC
This episode is hosted by Josie Baker, MS, LGC, and features Jeremy Davis, MD, a National Cancer Institute (NIH) surgical oncologist.Together, they discuss Dr. Davis' recent article published in the Journal of Medical Genetics titled “Decision-making and regret in patients with germline CDH1 variants undergoing prophylactic total gastrectomy.”This podcast was released during Patient Experience Week. Read our blog post to learn more about this podcast HERE
LINKS:Pod Virginia | PatreonLearn more about Jackleg MediaCheck out Black Virginia NewsIN THE NEWS:House Speaker Don Scott says he didn't appreciate Governor Glenn Youngkin showing up on the last day of the General Assembly session and asking Republicans to vote against the budget. The governor has a line item veto, which he can use to make all kinds of changes to the budget. When asked about the idea that he might issue a blanket veto of the entire bill, Youngkin said he wasn't far enough in the process to know quite yet. Senator Stella Pekarsky introduced a bill to make sure that DoorDash and StubHub weren't loading down customers with extra charges--and that bill died at the very end of the General Assembly session when some House Democrats did not support it. Likely, this was the work of some poweful lobbying from groups like the Virgina Chamber of Commerce.Senator Ghzala Hashmi introduced a bill that would require health insurance plans in Virginia cover contraception, but now the governor is adding an amendment that would allow for a religious or ethical exemption for people who don't want to provide coverage.TRIVIA: What happens if there is a tie in the election for Governor?At the Watercooler:- A Stateline article claims that Virginia's legislature has no working-class people holding office--but given the low pay for state officials, that's not quite true.- The governor's been on a roll of vetos, and shows no signs of stopping. What does this say about his positions and relationship to the legislature?Learn more at http://linktr.ee/JacklegMedia
Comic Book Chronicles Ep. 548: Ghosts of Pikes Past - Twas once again the night before the night before Christmas, and Agent_70 and Roddykat are doing a show! It starts off kind of shaky because of ironing out technical difficulties, but gets back into form by the time it ends!
Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss two recent papers exploring the utility of clarithromycin for early inflammatory responses in pneumonia and the role of probiotics as prophylaxis in recurrent UTIs. Two papers, here we go! Effectiveness of Prophylactic ...The post Episode 80 – Clarithromycin for Inflammation and Probiotics for Recurrent UTIs appeared first on Healthy Debate.
Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss two recent papers exploring the utility of clarithromycin for early inflammatory responses in pneumonia and the role of probiotics as prophylaxis in recurrent UTIs. Two papers, here we go! Effectiveness of Prophylactic ... The post Episode 80 – Clarithromycin for Inflammation and Probiotics for Recurrent UTIs first appeared on Healthy Debate. The post Episode 80 – Clarithromycin for Inflammation and Probiotics for Recurrent UTIs appeared first on Healthy Debate.
What strategies can reduce development time and accelerate access to next-generation monoclonal antibodies (mAbs) in the evolving SARS-CoV-2 variant landscape? Credit available for this activity expires: 1/26/25 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/999900?ecd=bdc_podcast_libsyn_mscpedu
Prophylactic, therapeutic, and empiric use of antimicrobial agents by AORNJournal
This week, Chris & Josh discuss the following topics (and so much more): Listener feedback on downtown properties Chris & Josh go to Vegas Willie Nelson A Sinatra dinner that wasn't Fountainebleau first thoughts New bubble craps in Vegas Want to contact us? Email: podcast@crapvegas.com Facebook: crapvegas.com/facebook Voicemail: crapvegas.com/voicemail Twitter: @VegasDuffy @SmallWhale13 @CrapVegas For more information, please visit our webpage at www.crapvegas.com or support us by becoming a Patreon subscriber at www.patreon.com/crapvegas
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-358 Overview: In this episode, we explore new data that could reshape how we approach sexually transmitted infection (STI) prevention in clinical practice. Discover how doxycycline can serve as prophylaxis for bacterial STIs in populations who are at high risk and come away with practical strategies for counseling patients on STI prevention. Tune in to enhance your clinical expertise and provide superior care to your patients. Episode resource links: Luetkemeyer AF, Donnell D, Dombrowski JC, et al. Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections. N Engl J Med. 2023;388(14):1296-1306. Guest: Alan M. Ehrlich MD, FAAFP Music Credit: Richard Onorato
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-358 Overview: In this episode, we explore new data that could reshape how we approach sexually transmitted infection (STI) prevention in clinical practice. Discover how doxycycline can serve as prophylaxis for bacterial STIs in populations who are at high risk and come away with practical strategies for counseling patients on STI prevention. Tune in to enhance your clinical expertise and provide superior care to your patients. Episode resource links: Luetkemeyer AF, Donnell D, Dombrowski JC, et al. Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections. N Engl J Med. 2023;388(14):1296-1306. Guest: Alan M. Ehrlich MD, FAAFP Music Credit: Richard Onorato
How effective is prophylactic laser for preventing fellow eye RT/RRD in patients with lattice degeneration who underwent uncomplicated primary RRD repair? NRR Journal Club with VBS moderator David Xu, MD, and panelists Prethy Rao, MD, and Barton Blackorby, MD, summarize a recent study that explored rates of fellow eye RT/RRD in this patient population by comparing cohorts who did and did not receive prophylactic laser in their fellow eye. The group dives deeper into the data to see how PVD presence, myopia severity, and phakic status affected rates of fellow eye RT/RRD, and asks whether and how these data can be applied to a modern surgical strategy.
Frank Zelenko is the brother of the late Dr. Vladimir Zelenko.He joins Ann to relay critical medical information to save lives as humanity worldwide is being challenged with aggressive RNA viruses. No matter where the origin, the Zelenko Protocol will prophylactic and treat the invading virus. Frank is also very outspoken on the current war in Israel as it relates to the worldwide problem of corrupt governments in power everywhere.https://annvandersteel.comhttps://annvandersteel.substack.comhttps://RightNow.NewsHARD HITTING TRUTH AND PERSONAL IMPACT STORIES THAT MAKE A DIFFERENCESPECIAL GUEST:FRANK ZELENKO: https://www.youtube.com/@TheNationofIsrael613https://vladimirzelenkomd.com/Operation Burning Edge is a serious operation studying the negative impacts and downstream carnage caused by the Biden policies and illegal unconstitutional border migration forever changing the tapestry of America.Cartels are in control of the border running drugs, people and disease into America. Zoonotic disease are jumping from people to animals and back again leaving our cattle industry very vulnerable to slaughter as TB is making a comeback into humans and animals. The U.S. government is funding this invasion and aiding and abetting the trojan army being installed in America. You can support this work at GiveSendGo.com/BurningEdge.Stay tuned for daily updates weeknights on Brighteon TV at 8pm and Rumble and the rest at 9pm.Please consider supporting Operation Burning Edge: https://givesendgo.com/burningedgeFamed war correspondent, Michael Yon, and I are organizing a Southern border Expedition in Texas and Panama for the months of August/September. We have the top of the line gear and security for this entire trip filled with migrant encounters, helicopters, fixed wing aircraft, Law Enforcement, Customs and Border Patrol, Congressman and more who all want to learn from the intel gathering we will be doing in the field. Live reporting daily from the field with the latest on the invasion and who is behind it along with who is REALLY TRYING to stop it.'HELP US COVER THE INVASION:- Top of the line Military Grade Communications, Gear, and Accommodations - Military Grade Communications Gear for ground-to-ground, ground-to-air, and satellite comms.- Starlink for broadband communications and broadcasting- Various sensors, including $500,000 cooled thermal camera attached to an $80,000 fifty-foot mast.- Image intensifiers, handheld thermal scanners, high quality low-light optics including the most modern optics platforms.- IR spotlights & detectors- Helicopter coverage- Multiple aviation options including helicopters and various fixed wing aircraft allowing for video capture and real-time thermal imaging.- Advanced drone technology with FAA certified Drone pilots.- Advanced audio and video equipment for discreet and overt audio/video capture - Multiple vehicles, RVs, and staff with military trained securityFollow Michael & Ann on Twitterhttps://twitter.com/Michael_Yonhttps://twitter.com/annvandersteelLIVE: BRIGHTEON.TV 8PM ETSPONSORED BY:ADVANTAGE GOLD1-800-900-8000SATELLITE PHONE STOREhttps://sat123.comLIGHTS OUT BEEFhttps://LightsOutBeef.comC60 EVO -My health and beauty secret!C60 EVO ORGANIC EDIBLE OILS ~ FOR RADIANT ENERGY & MENTAL FOCUSESS60 (PURE C60) INCREASES FLEXIBILITY, IMMUNITY & LONGEVITYFOR PEOPLE & PETShttps://www.c60evo.com/annvandersteel/ 10% OFF PROMO CODE EVAVALIAS IDhttps://AliasID.com PROMO CODE “AV”MY PILLOWhttps://MyPillow.com PROMO CODE “AV”EMF DEFENSEhttps://www.ftwproject.com/ref/470/STREAMING 8PM EThttps://RightNow.NewsSTREAMING 9PM ETRUMBLE https://rumble.com/AnnVandersteel/liveGETTR https://gettr.com/user/annvandersteelCLOUTHUB https://clouthub.com/c/gyFG3mMSFACEBOOK https://www.facebook.com/ann.vandersteelYOURNEWS.COM https://yournews.com/area/videos/TWITTER https://twitter.com/annvandersteelEMAILRightNowAnn@protonmail.comSNAIL MAILAnn Vandersteel℅ P.O. BOX 386Palm City, Florida [34991]SPONSORS:https://lightsoutbeef.comhttps://AliasID.com Promo Code AVhttps://zstacklife.com Promo FOUNDATIONhttps://www.mypillow.com/ Promo AVhttps://www.ftwproject.com/ref/470/Transform the harmful wireless fields from; cell towers, smart meters, smartphones, internet router and your television, into more beneficial energy for you and your plants and petsBECOME A CITIZEN JOURNALISThttps://yournews.com/become-a-yournews-citizen-journalist/FOLLOW & SUBSCRIBE:https://AnnVandersteel.Substack.comhttps://twitter.com/annvandersteelhttps://truthsocial.com/@annvandersteelhttps://gettr.com/i/annvandersteelhttps://t.me/AnnVandersteelTruthhttps://annvandersteel.locals.comhttps://app.clouthub.com/#/users/u/AnnVandersteel/postshttps://gab.com/AnnVandersteelhttps://facebook.com/annvandersteelhttps://www.linkedin.com/in/ann-vandersteel-312310260/FAIR USE NOTICE These pages may contain copyrighted material the use of which has not been specifically authorized by the copyright owner. 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Neste episódio do Journal Club, voltamos a apresentar artigos bem recentes e com desafios comuns para quem trabalha na UTI Neonatal.Não esqueça: você pode ter acesso aos artigos:1. Viral Infections and Neonatal Necrotizing Enterocolitis: A Meta-analysis - "Infecções Virais e Enterocolite Necrosante Neonatal: Uma meta-análise"2. Short-course empiric antibiotic therapy for possible early-onset sepsis in the NICU - "Antibioticoterapia empírica de curta duração para possível início precoce sepse na UTIN"3. Human milk-derived fortifiers are linked with feed extension due to Hypoglycemia in infants
Today Laura Carfang is joined with Amy Gallagher, who discusses her decision to have a prophylactic double mastectomy due to her positive BRCA1 mutation. Amy shares her personal journey with breast and ovarian cancer in her family, highlighting the importance of genetic testing and raising awareness about the potential for inherited mutations on the paternal side.The episode concludes with an inspirational discussion about Amy's role as the executive director of Firefly Sisterhood, a non-profit organization dedicated to supporting individuals diagnosed with breast cancer.Topics Discussed:00:04:57 Importance of genetic testing00:17:04 Open communication with family and children00:22:08 Support for breast cancer patients.00:23:44 Supporting breast cancer patients through personalized mentorship.00:28:21 Support for breast cancer patients.Follow us on InstagramLaura and Will: https://www.instagram.com/laura_and_will/SurvivingBreastCancer.org: https://www.instagram.com/survivingbreastcancerorg/About Amy GallagherExecutive Director, Amy Gallagher, comes to Firefly Sisterhood in April 2021 with a deep connection to the mission of helping women diagnosed with breast cancer. Having an extensive family history of breast and ovarian cancer, Amy was prompted to be tested for genetic mutation in the BRCA1 gene which came back positive. In June 2017, Amy opted to have a prophylactic bilateral mastectomy to reduce her chance of developing breast cancer.Amy has an extensive background in health and wellness non-profit work, especially those that help people diagnosed with cancer. She has strengths in event project management and logistics, volunteer and committee planning, fundraising and development and organizational strategic planning.Having spent the last five years working alongside volunteers within breast cancer organizations, Amy understands the importance of the connections formed at Firefly Sisterhood. Ensuring that women have the support when they need it most is what motivates her every day.+++++++++++++++++++++SBC's Mission: To empower those diagnosed with breast cancer and their families from day one and beyond. About SurvivingBreastCancer.org.:SurvivingBreastCancer.org, Inc. (SBC) is a Federally recognized 501(c)(3) non-profit virtual platform headquartered in Boston with a national and global reach. Through education, community, and resources, SurvivingBreastCancer.org supports women and men going through breast cancer. We provide a sanctuary of strength, compassion, and empowerment, where those diagnosed with cancer unite to share their stories, learn invaluable coping strategies to manage wellness and mental health, and find solace in the unbreakable bond that fuels hope, resilience, and the courage to conquer adversity.Website:https://www.survivingbreastcancer.org/Events:https://www.survivingbreastcancer.org/eventsDonate NowPlease consider making a donation.https://www.survivingbreastcancer.org/donate-nowSupport the show
Dr. Nayantara Coelho-Prabhu, Mayo Clinic gastroenterologist specializing in the care of patients with gastrointestinal bleeding and endoscopy, talks through many aspects of acute GI bleeding. She helps to clarify the prioritization of medications, when to incorporate imaging, broadens our differentials for upper and lower GI bleeding, gives mindblowing advice on stool guiac testing and SO much more in this over-stuffed (or should we say constipated) chapter of Always on EM. There is also a special cameo from Dr. Luke Wood going over how to insert a Minnesota tube (esophageal balloon tamponade device)! CONTACTS X - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch Email - AlwaysOnEM@gmail.com RECOMMENDATION: Dieulafoy lesion video from New England Journal of Medicine: https://youtu.be/tzJQDen1nug?si=zOmywZ1VN3VvA004 REFERENCES: Drescher MJ, Stapleton S, Britstone Z, Fried J, Smally AJ. A call for reconsideration of the use of fecal occult blood testing in emergency medicine. Journal of Emerg Med. 2020. 58(1)54-58 Mathews BK, Ratcliffe T, Sehgal R, Abraham JM, Monash B. Fecal Occult Blood testing in hospitalized patients with upper gastrointestinal bleeding. Journal of Hospital Medicine. 2017. 12(7)567-569 Harewood GC, McConnell JP, Harrington JJ, Mahoney DW, Ahlquist DA. Detection of occult upper gastrointestinal bleeding: performance in fecal occult blood tests. Mayo Clin Proc. 2002 Jan;77(1):23-28 Blatchford O, et al. A risk score to predict need for treatment for upper gastrointestinal haemorrhage. Lancet 2000. Oct 14;356(9238):1318-21 Blatchford O, Davidson LA, Murray WR, Blatchford M, Pell J. Acute upper gastrointestinal haemorrhage in west of scotland: case ascertainment study. BMJ 1997. Aug 30;315(7107):510-4 Chen IC, Hung MS, Chiu TF, Chen JC, Hsiao CT. Risk scoring systems to predict need for clinical intervention for patients with nonvariceal upper gastrointestinal tract bleeding. Am J Emerg Med. 2007 Sep;25(7):774-9 Laine L, Barkun AN, Saltzman JR, Martel M, Leontiadis GI. ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding. Am J Gastroenterol. 2021 May 1;116(5):899-917 Roberts I, Shakur-STill H, Afolabi A, et al. Effects of High-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet 2020. 395(10241):1927-1936 Aziz M, Haghbin H, Gangwani MK, Weissman S, Patel AR, Randhawa MK, Samikanu LB, Alyousif ZA, Lee-Smith W, Kamal F, Nawras A, Howden CW. Erythromycin improves the quality of esophagogastroduodenoscopy in upper gastrointestinal bleeding: a network meta-analysis. Dig Dis Sci 2023. Apr;68(4):1435-1446 Abraham NS, Barkun AN, Sauer BG, et al. American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of anticoagulants and antiplatelets during acute gastrointestinal bleeding and the periendoscopic period. Am J Gastroenterol 2022;00:1-17 Vigano GL, Mannucci PM, Lattuada A, Harris A, Remuzzi G. Subcutaneous desmopressin (DDAVP) shortens the bleeding time in uremia. Am J Hematol 1989. May;31(1):32-5 Chavez-Tapia NC, Barrientos-Gutierrez T, Tellez-Avila FL, Soares-Weiser K, Uribe M. Antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding. Cochrane Database Syst Rev 2010. Sep 8;2010(9):CD002907 Gao Y, Qian B, Zhang X, Liu H, Han T. Prophylactic antibiotics on patients with cirrhosis and upper gastrointestinal bleeding: A meta-analysis. PLoS One 2022. Dec 22;17(12):e0279496 Steffen R, Knapp J, Hanggi M, Iten M. Use of the REBOA catheter for uncontrollable upper gastrointestinal bleeding with hemorrhagic shock. Anaesthesiologie 2023. May;72(5):332-337 Sato M, Kuriyama A. Countering hemorrhagic shock due to duodenal variceal rupture with resuscitative endovascular balloon occlusion of the aorta. Am J Emerg Med 2023. Feb;64:204.e1-204.e3
In this episode, we review the high-yield topic of Impending Fracture & Prophylactic Fixation from the Pathology section. Follow Orthobullets on Social Media: Facebook: www.facebook.com/orthobullets Instagram: www.instagram.com/orthobulletsofficial Twitter: www.twitter.com/orthobullets LinkedIn: www.linkedin.com/company/27125689 YouTube: www.youtube.com/channel/UCMZSlD9OhkFG2t25oM14FvQ --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we discuss screening for BV to prevent preterm birth. Then new data about the safety of obstetric care in rural vs urban hospitals of different sizes. Plus, new evidence that prophylactic salpingectomy is working and new data about vaginal cuff dehiscence and the analogy between clinical studies and lab tests. 0:02Treating Bacterial Vaginosis in Pregnancy10:12Morbidity Rates in Rural and Urban Hospitals20:43Hospital Size and Patient Care Impact32:56Maternity Deserts37:04Salpingectomy for Ovarian Cancer Prevention44:10Analogy of Clinical Trials49:53Vaginal Cuff Dehiscence
References Mol Neurobiol 2020 Jun; Vol. 57 (6), pp. 2654-2670 Brain Res. 2009 Sep 22; 1290: 1–11. JAMA.2003;289(20):2651-2662. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message
Ох уж эти ежегодные летние "профилактические" отключения горячей воды... Каждый прошёл через это не раз, в т.ч. и в этом году, кто-то сейчас сидит без "горячки", а кого то эта радость ожидает в августе! Уверен: после танцев под этот сэт будет только одна потребность - охладиться! А значит холодной воды, в данном случае, будет вполне достаточно!!!
PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast
Go online to PeerView.com/WEM860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Are you aware of the evidence supporting the use of innovative EHL FVIII therapies for the prophylactic management of hemophilia A? Find out in this activity based on a “MasterClass” event recorded at the 2023 Congress of the International Society on Thrombosis and Haemostasis. Hear what hemophilia experts are saying about the latest clinical evidence that supports the use of innovative EHL FVIII therapy in hemophilia as they link the data directly to case-based decisions in real-world settings—with a goal of clearly illustrating the practicalities of safely using novel and emerging factor products. The experts also provide guidance on implementing evidence-based protocols and preventing and managing complications in the context of EHL FVIII therapy. Upon completion of this activity, participants should be better able to: Assess the latest safety, efficacy, and pharmacokinetic data among currently approved and emerging EHL FVIII products for prophylaxis of hemophilia A; Develop personalized prophylactic regimens with novel and emerging EHL FVIII products based on patient- and disease-specific factors; and Manage practical aspects of care, such as patient education, adherence counseling, monitoring, and AE management, when using novel and emerging EHL FVIII products for prophylaxis of hemophilia A
Who else out there is as excited as I am that we are finally talking about all things menopause? I remember hitting peri-menopause in my 40's and having no clue what was happening and that there was help! Fast forward a little bit from there and I met Dr. Mary Claire Haver who is not only an expert but also on a mission to help women through all phases of menopause. As she says it is a “labor of love and she is here for it!” I am thrilled she is here today to talk with us about taking the lead in our menopause journey. She is changing the game, so get ready to take notes. Today, this one's for you ladies! Let's meet Dr. Mary Claire Haver:As one third of women are currently in some phase of menopause, it is an essential aspect of women's lives, yet so stigmatized and shrouded with shame and steeped in anxiety over aging that many women still don't feel comfortable talking about their menopause journey with friends, family, and most crucially, their doctors. Kept in the dark, menopause becomes more difficult to understand and control, leaving many women to suffer in silence. Dr. Mary Claire Haver is here to change all of that. Recently the Board Certified OB-GYN has set TikTok alight with an unlikely subject---menopause---amassing nearly 2 million followers by posting advice for women going through it. Dr. Haver understands that women's healthcare is indire need of a change. So often, when women talk to their healthcare providers about issues such as weight gain, sleep changes, hot flashes, and mental health issues, they are dismissed with platitudes like "it's just your hormones" or it's "just your age," and given the advice to "eat less and exercise more."The problem has led Dr. Haver to develop The Galveston Diet, a three-pronged lifestyle plan that encourages fuel refocusing, intermittent fasting, and anti-inflammatory nutrition to manage hormonal symptoms, stabilize weight, and revitalize the body as it ages to provide benefits that will last a lifetime.Dr. Haver has always had a passion for learning and a strong work ethic. She is a graduate of Louisiana State University Medical Center, and completed her residency in Obstetrics and Gynecology at the University of Texas Medical Branch. In addition to her clinical work, she became an instructor of Obstetrics and Gynecology at the University of Texas Health Science Center at Houston, has served as a Hospitalist, the Associate Residency Director and Assistant Professor at the University of Texas Medical Branch Department of Obstetrics and Gynecology, and is certified in Culinary Medicine by Tulane University School of Medicine. Highlights from this episode:(06:45) Getting hyped up for the menopause(13:57) Move your body in a way that brings joy(17:03) Fall like a football player(27:31) It's trial and error(33:07) How to deal with hot flashes(35:52) Prophylactic testing(41:21) The best supplements Connect with Dr. Haver:www.galvestondiet.comTikTok - @drmaryclaireInstagram - drmaryclaire and the.galveston.dietFacebook - The Galveston Diet Mary Claire Haver, MDYouTube -
Expert Approach to Hereditary Gastrointestinal Cancers presented by CGA-IGC
This episode is hosted by Josie Baker, MS, CGC, a genetic counselor at The Ohio State University, and features Rachael Lopez, MPH, RD, CSO, a clinical research dietitian at the National Institutes of Health. Together they discuss the considerations for individuals with Hereditary Diffuse Gastric Cancer Syndrome when considering a prophylactic gastrectomy. This episode highlights the professional experience when working with these individuals before and after surgery, as well as the challenges individuals may face during this process.
Firstly, a huge shout out to a very special triplet...PIZZA GIRL! In this episode these two discuss the ins and outs of NYC, fake coffee orders, and even the absurdities of German drinking games.
This week we have special guest, Dr. Adam Spivak, to talk about the new study on doxycycline post-exposure prophylaxis for STIs. Dr. Spivak is an infectious disease expert and works in both an HIV clinic and a free PrEP clinic. I also review the latest COVID-19 anticoagulation trial and a paper looking at rates of fracture non-union in people who receive bisphosphonates. Check it out! Doxycycline Post-exposure Prophylaxis for STIsHigh dose prophylactic anticoagulation in COVID-19Bisphosphonate and Rates of Fracture Non-unions Music from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
Please join Drs. Graham Skelhorne-Gross, Jordan Nantais and Ashlie Nadler from our Emergency General Surgery Team for a discussion on cirrhotic patients. Child-Pugh Score (https://www.mdcalc.com/calc/340/child-pugh-score-cirrhosis-mortality) · Bilirubin, albumin, INR, ascites, encephalopathy · Used to predict operative mortality based on cirrhosis severity · Mortality in EGS: - Child-Pugh A: 10% electively and 22% emergently - Child-Pugh B: 30% electively and 38% emergently - Child-Pugh C: 80% electively and up to 100% emergently Model for End Stage Liver Disease (MELD) (https://www.mdcalc.com/calc/10437/model-end-stage-liver-disease-meld?utm_source=site&utm_medium=link&utm_campaign=meld_12_and_older) · creatinine, bilirubin, INR, and sodium · MELD < 20 – 1% increase in mortality with each point increase · MELD > 20 – 2% increase in mortality with each point increase Pre-operative Planning · Identification of cirrhosis with physical examination, bloodwork and imaging · Involvement of other medical services (internal medicine, hepatology, ICU) as needed · Cirrhosis optimization, if possible · Abdominal wall mapping Unexpected Intraoperative Finding Communicate unexpected findings to the operative team and think of additional adjuncts you may need such as additional ports, topical hemostatic agents or energy devices. Think about why you are in the OR. If its an elective situation and can wait, consider bailing. If its emergent, you may have to do something more definitive. Exposure may be a challenge, you may have to alter your typical approach including where the assistant grabs and retracts. Extra hands are helpful. Bleeding can be a big deal. If possible, map out the abdominal wall ahead of time with cross-sectional imaging. Stay away from varices around the umbilicus or porta Ventral Hernia + Cirrhosis · Ideally, control ascites pre-operatively, if you can't consider leaving drains · Small (< 2cm) hernias close primarily · Larger (>2cm) hernias repair with mesh unless infected filed (controversial) · Minimally invasive repairs can be performed Benign Biliary Disease + Cirrhosis · Incidence of gallstones is 4-5 times higher in cirrhotic patients · Prophylactic laparoscopic cholecystectomy (LC) generally not done · LC generally considered acceptable in CP A or B but not C (exceptions: HD instability, gangrenous cholecystitis, hemorrhagic cholecystitis) · Cholecystostomy and ERCP are safe References: Bleszynski, M. et. Al. Acute care and emergency general surgery in patients with chronic liver disease: how can be optimize perioperative care? A review of the literature. 2018. World Journal of Emergency Surgery; 13:32 Mansour A, Watson W, Shayani V, et al. Abdominal operations in patients with cirrhosis: still a major surgical challenge. Surgery. 1997;122:730–5. Yeom SK, Lee CH, Cha SH, Park CM. Prediction of liver cirrhosis, using diagnostic imaging tools. World J Hepatol. 2015 Aug 18;7(17):2069-79. doi: 10.4254/wjh.v7.i17.2069. PMID: 26301049; PMCID: PMC4539400. Jain D, Mahmood E, V-Bandres M, Feyssa E. Preoperative elective transjugular intrahepatic portosystemic shunt for cirrhotic patients undergoing abdominal surgery. Ann Gastroenterol. 2018 May-Jun;31(3):330-337. doi: 10.20524/aog.2018.0249. Epub 2018 Mar 15. PMID: 29720858; PMCID: PMC5924855. **Fellowship application link: https://forms.gle/PiKM2MMQpE5jSAeW7 Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out other Emergency General Surgery episode here: https://behindtheknife.org/podcast-category/emergency-general-surgery/
Welcome to PsychEd — the psychiatry podcast for medical learners, by medical learners. This episode is an introduction to the use and monitoring of lithium in bipolar disorder. Join Tingting Yan (CC4) and Dr. Alex Raben (staff psychiatrist at CAMH and lecturer at the University of Toronto) for a lively case-based discussion. Learning Objectives The learning objectives for this episode are as follows: By the end of this episode, the listener will be able to… Describe the indications and process for starting lithium Monitor and interpret serum lithium levels List short and long-term adverse effects of lithium Produced by: Tingting Yan CC4, Dr. Alex Raben (staff psychiatrist) Hosts: Tingting Yan, Alex Raben Audio editing by: Alex Raben Show notes by: Alex Raben Contents: Learning objectives: 00:44 Lithium background and brief history: 2:48 Women's health and lithium: 5:28 Underutilization of lithium: 8:02 Baseline blood work for lithium: 11:32 Choosing a lithium starting dose: 14:32 Lithium serum levels: 16:17 Lithium titration: 20:46 Lithium toxicity: 23:48 Lithium side effects: 26:52 Summary: 32:11 References Baastrup PC, Poulsen JC, Schou M, Thomsen K, Amdisen A. Prophylactic lithium: double blind discontinuation in manic-depressive and recurrent-depressive disorders. Lancet. 1970;2(7668):326-330. doi:10.1016/s0140-6736(70)92870-9 Bauer LA. Chapter 17. Lithium. In: Bauer LA. eds. Applied Clinical Pharmacokinetics, 2e. McGraw Hill; 2008. Accessed March 16, 2023. https://accesspharmacy.mhmedical.com/content.aspx?bookid=510§ionid=40843106 Chokhawala K, Lee S, Saadabadi A. Lithium. StatPearls. Davis J, Desmond M, Berk M. Lithium and nephrotoxicity: a literature review of approaches to clinical management and risk stratification. BMC nephrology. 2018 Dec;19:1-7. Draaisma D. Lithium: the gripping history of a psychiatric success story. Nature. 2019 Aug 1;572(7769):584-6. Hedya SA, Avula A, Swoboda HD. Lithium toxicity. Malhi GS, Bell E, Outhred T, Berk M. Lithium therapy and its interactions. Australian Prescriber. 2020 Jun;43(3):91. Malhi GS, Gessler D, Outhred T. The use of lithium for the treatment of bipolar disorder: Recommendations from clinical practice guidelines. J Affect Disord. 2017;217:266-280. doi:10.1016/j.jad.2017.03.052 McKnight RF, Adida M, Budge K, Stockton S, Goodwin GM, Geddes JR. Lithium toxicity profile: a systematic review and meta-analysis. Lancet. 2012;379(9817):721-728. doi:10.1016/S0140-6736(11)61516-X Patorno E, Huybrechts KF, Bateman BT, Cohen JM, Desai RJ, Mogun H, Cohen LS, Hernandez-Diaz S. Lithium use in pregnancy and the risk of cardiac malformations. New England Journal of Medicine. 2017 Jun 8;376(23):2245-54. Tondo L, Alda M, Bauer M, Bergink V, Grof P, Hajek T, Lewitka U, Licht RW, Manchia M, Müller-Oerlinghausen B, Nielsen RE. Clinical use of lithium salts: guide for users and prescribers. International journal of bipolar disorders. 2019 Dec;7(1):1-0. Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, Sharma V, Goldstein BI, Rej S, Beaulieu S, Alda M. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar disorders. 2018 Mar;20(2):97-170. CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association. For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information, visit our website at psychedpodcast.org.
We're coming to you live from the American Academy of Orthopaedic Surgeons annual meeting in Las Vegas, our largest orthopaedic conference. This year, over 20,000 orthopedic professionals gathered at the AAOS meeting to take part. The educational program is comprised of instructional course lectures, video theater, live surgeries, podium presentations and research posters.Over the next several episodes we're going to be reviewing five sports medicine posters that were presented at the AAOS meeting. On this podcast we try to review the most updated literature on different sports medicine topics. So, reviewing some of the posters that were just presented at AAOS is particularly exciting for us because this is very new data. So new that most of this data has not even been published yet.We're joined by Dr. Brian Waterman to get his take on these poster presentations.Dr. Brian Waterman is a board-certified, orthopedic surgeon specializing in adult and pediatric sports medicine, cartilage restoration and joint preservation, complex knee surgery and shoulder and elbow care. He is the Chief of sports medicine at Wake Forest University and the Director of their sports medicine fellowship program. Dr. Waterman completed his orthopedic surgery residency at William Beaumont Army Medical Center and served 13 years in the U.S. Army, earning multiple honors including the Meritorious Service Medal and Army Commendation Medal.Dr. Waterman then went on to complete a sports medicine fellowship at Rush University Medical Center in Chicago. He is the team physician for Wake Forest University, the Winston-Salem Dash, U.S. Ski and Snowboard and several local high schools.Dr. Waterman is an associate editor for the Arthroscopy Journal and is on the Board of Directors for Arthroscopy Association of North America. Given his extensive experience with orthopedic research, Dr. Waterman led the sports medicine poster tour at AAOS this year, so we're looking forward to getting his unique perspective on these poster presentations.Featured Poster:Should NFL Offensive Linemen Use Prophylactic Knee Braces? A Retrospective Analysis of Usage Trends, Player Performance, and Major Knee Injury. Offensive linemen in American football are prone to high-energy valgus forces to the knee and associated ligament injuries.Use of prophylactic knee braces has been hypothesized to protect against these injuries but the evidence backing this up has been inconclusive at best.Robert Gallo and his colleagues at Penn State performed a prospective cohort study from 2014 to 2020, comparing NFL offensive lineman who chose to wear prophylactic knee braces to lineman who did not. They evaluated injury rates as well as performance metrics. Interestingly, the authors reported that from 2014 to 2020, the prevalence of knee brace usage declined linearly, from 16% in 2014 to 5% in 2020.
The dreaded Surgical Site Complications! Join Drs. Ashlie Nadler, Jordan Nantais and Graham Skelhorne-Gross from our Emergency General Surgery Team as they discuss surgical site complications and prevention techniques. Paper 1: Arnold et. al. (2019) Not a Routine Case, Why Expect the Routine Outcome? Quantifying the Infectious Burden of Emergency General Surgery Using the NSQIP. American Surgeon - NSQIP database 2005-2016 (>800,000 patients) including open/laparoscopic cholecystectomies, ventral hernia repairs, and partial colectomies - Comparing outcomes in emergent vs elective cases - Primary outcome: aggregate of SSIs which includes wound disruption, superficial SSI, deep SSI, and organ space SSI - Results: -- ↑SSI in the emergency group (5.3% vs 3.6%) -- When controlling for multiple variables, emergency surgery associated with more SSIs (OR 1.15). Paper 2: Lakhani et. al. (2022) Prophylactic negative pressure wound dressings reduces wound complications following emergency laparotomies: A systematic review and meta-analysis. Surgery - NPWD remove excess fluid from subcutaneous space, ↓ collections/contaminants, promote angiogenesis, fibroblast infiltration - Literature review 2005-2022 (NPWD, laparotomy, SSI) - 1199 patients included (566 NPWD, 633 standard dressings) - Results: -- NPWD ↓ wound infection (OR 0.43) and wound breakdown (OR 0.36) -- No change in LOS, readmission Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out other Emergency General Surgery episodes here: https://behindtheknife.org/podcast-category/emergency-general-surgery/
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