Podcasts about critically ill patients

Acute kidney injury is a frequent complication of critical illness, and a subgroup of these patients will require renal replacement therapy. In this episode. Dr. Sergio Zanotti discusses optimizing renal replacement therapy in the ICU. He is joined by Dr. Michael J. Connor, Jr., a practicing intensivist and nephrologist. He is a professor and senior physician of critical care medicine and nephrology at the Divisions of Pulmonary, Allergy, Critical Care, & Sleep Medicine and Renal Medicine at Emory University School of Medicine. In addition, he is the director of critical care nephrology at the Emory Critical Care Center at Grady Memorial Hospital. Additional resources: Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury. Wald R, et al. Intensive Care Med 2022: https://pubmed.ncbi.nlm.nih.gov/36066597/ Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit. AKIKI Study Group. N Engl J Med 2016: https://pubmed.ncbi.nlm.nih.gov/27181456/ Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients with Acute Kidney Injury. ELAIN Trial. JAMA 2016: https://pubmed.ncbi.nlm.nih.gov/27209269/ Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis. IDEAL-ICU Investigators. N Eng J Med 2018: https://pubmed.ncbi.nlm.nih.gov/30304656/ Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. STARRT-AKI Investigators. N Engl J Med 2020: https://pubmed.ncbi.nlm.nih.gov/32668114/ Comparison of two delayed strategies for renal therapy initiation for severe acute kidney injury. AKIKI 2 Trial. Lancet 2021: https://pubmed.ncbi.nlm.nih.gov/33812488/ Books and Music mentioned in this episode: The Invisible Life of Addie LaRue. By V.E. Schwab: The Invisible-Life-Addie-LaRue Moon Music. By Coldplay: Moon-Music-Coldplay

Admission to the intensive care unit (ICU) can be a challenging experience for patients and their families. Psychological burdens, including symptoms of anxiety, depression and post-traumatic stress, are among the most reported during the ICU stay.A recent study has been carried out as a joint project between France and the United States in which the experts have designed an intervention to improve outcomes for patients' families. For this intervention, they evaluated the nurse facilitator to support, model and teach communication strategies that will help in securing care aligned with patients' goals at the ICU. To learn more about this intervention, we interviewed one of the main authors, Nancy Kentish Barnes. Listen to our podcast for deeper insights into this study!

Join endocrine experts Vin Tangpricha, MD, PhD, FACE, Editor-in-Chief of Endocrine Practice (EP) and Professor of Medicine at Emory University School of Medicine, and Cecilia C. Low Wang, MD, FACE, FACP, Professor of Medicine and Medical Director for the Glucose Management Team at the University of Colorado, as they discuss Dr. Low Wang's impactful EP article titled "Safety and Efficacy of Insulins in Critically Ill Patients Receiving Continuous Enteral Nutrition." Tune in as they explore strategies for managing hyperglycemia and hypoglycemia in hospitalized patients on continuous tube feeds, evaluate insulin regimens such as 70/30 Q-8 hours and basal-bolus, examine differences in glycemia management for patients with and without diabetes, and discuss ways to optimize glycemic control. View the full article in the April 2024 issue of EP here.

Dr. Michael Lanspa chats with Dr. Hannah Wunsch about her paper, "Evaluation of Etomidate Use and Association with Mortality Compared with Ketamine among Critically Ill Patients."

CHEST November 2024, Volume 166, Issue 5 Mariachiara Ippolito, MD, and Andrea Cortegiani, MD, join CHEST Journal Podcast Moderator Gretchen Winter, MD, to discuss their research exploring the association of different methods for conducting spontaneous breathing trials with the risk of reintubation among critically ill adult patients. DOI: https://doi.org/10.1016/j.chest.2024.06.3773   Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.  

In the September 2024 episode of Critical Decisions in Emergency Medicine, Drs. Danya Khoujah and Wendy Chang discuss pediatric wrist injuries and postintubation care of critically ill patients. As always, you'll also hear about the hot topics covered in CDEM's regular features, including muscositis and rash after an acute febrile illness in Clinical Pediatrics, traumatic arthrotomy status post total knee arthoplasty in Orthopedics and Trauma, bursal aspiration and injection in The Critical Procedure, antimicrobial therapy for pediatric community-acquired pneumonia in The LLSA Literature Review, and a diving accident in The Critical Image.

In this podcast, JPEN Editor-in-Chief Dr. Kenneth Christopher, interviews Fabio Araujo, a registered dietitian specializing in critical care nutrition with a research focus on critical care nutrition support protein and malnutrition at the Alberta Health Services' Peter Lougheed Centre ICU in Clagary, Alberta. Araujo is the first author of the JPEN original research article “Association Between Protein Intake and Functional Capacity in Critically Ill Patients: A Retrospective Cohort Study”. Business Corporate by Alex Menco | alexmenco.net Music promoted by www.free-stock-music.com Creative Commons Attribution 3.0 Unported License creativecommons.org/licenses/by/3.0/deed.en_US October 2024

In this episode of the Saving Lives Podcast, we discuss a recent randomized controlled trial exploring the use of minocycline to prevent delirium in critically ill patients. The study reveals that minocycline may significantly reduce delirium incidence and hospital mortality, offering a promising new pharmacologic approach. The Vasopressor & Inotrope Handbook I have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for anyone caring for critically ill patients (check out the reviews)! You have several options to get a physical copy. If you're in the US, you can order ⁠A SIGNED & PERSONALIZED COPY for $29.99⁠ or via ⁠AMAZON for $32.99⁠ (for orders in or outside the US). Ebook versions are available via ⁠AMAZON KINDLE for $9.99⁠, ⁠APPLE BOOKS⁠, and ⁠GOOGLE PLAY⁠. ¡Excelentes noticias! Mi libro ha sido traducido al español y está disponible a traves de ⁠AMAZON⁠. Las versiones electrónicas están disponibles para su compra for solo $9.99 en ⁠AMAZON KINDLE⁠, ⁠APPLE BOOKS⁠ y ⁠GOOGLE PLAY⁠. Citation Dal-Pizzol F, Coelho A, Simon CS, Michels M, Corneo E, Jeremias A, Damásio D, Ritter C. Prophylactic Minocycline for Delirium in Critically Ill Patients: A Randomized Controlled Trial. Chest. 2024 May;165(5):1129-1138. doi: 10.1016/j.chest.2023.11.041. Epub 2023 Dec 1. PMID: 38043911. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Show notes at pharmacyjoe.com/episode952. In this episode, I'll discuss the optimal urine output cutoff point to identify acute kidney injury in critically Ill patients. The post 952: What is the optimal urine output cutoff point to identify acute kidney injury in critically Ill patients? appeared first on Pharmacy Joe.

Send us a Text Message.Diese Woche besprechen wir die Arbeit von Rahmel et al. zur ketogenen Ernährung in der Sepsis: Rahmel et al. An open-label, randomized controlled trial to assess a ketogenic diet in critically ill patients with sepsis. Sci Transl Med. 16,eadn9285(2024).DOI:10.1126/scitranslmed.adn9285Mit im Studio dabei: Dr. Marie Koch, wissenschaftliche Mitarbeiterin der Klinik fr Anästhesiologie am UKHD. 

How effective is red light therapy for reducing stress when you irradiate both your brain and your gut?Can methylene blue reduce mortality in those critically ill?How safe and effect is C60 according to a recent toxicity report?​​​​In today's solosode, we're diving back into the research! And it ended up being a sheer coincidence that we're covering each topic of The Mitochondrial Triad. The first article looks at how beneficial photobiomodulation can be for reducing stress when you target both the brain and the gut to enhance mental health via the gut-brain axis. The second article is an abstract of a meta-analysis of randomized controlled trials that demonstrates the efficacy and safety of methylene blue for critically ill individuals and perioperative patients. The last study comes from our friends at SES Research where they are studying the toxicity of carbon 60 to verify its safety and efficacy. With C60 being such a new supplement for human consumption, SES Research is going through the necessary and proper steps to demonstrate the safety of this novel and seemingly beneficial molecule. Hopefully, studies like this will help C60 become more widely adopted so that more people can benefit from it. If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key points: Product Announcement - 00:01:26 - 00:02:11 Summer in Montana and Outdoor Activities - 00:02:11 - 00:03:04 Red Light Therapy for Mitochondrial and Mental Health - 00:03:04 - 00:04:08 Brain-Gut Photobiomodulation and Stress-Induced Cognitive Changes - 00:04:08 - 00:07:29 Combining Brain and Gut Photobiomodulation - 00:07:29 - 00:08:50 Regular Red Light Therapy for Enhanced Health - 00:08:50 - 00:12:27 Full Body Devices and Systemic Treatment - 00:16:42 - 00:17:45 Photobiomodulation Benefits and Disease Prevention - 00:17:45 - 00:21:24 Methylene Blue for Critically Ill Patients - 00:22:14 - 00:27:56 Introduction to C60 (Carbon 60) - 00:27:56 - 00:31:27 Safety Studies on Pure C60 - 00:31:27 - 00:33:44 Recent Study on C60 in Rats - 00:33:44 - 00:37:18 Importance of High-Quality C60 Products - 00:37:18 - 00:42:42 Testing and Benefits of High-Purity C60 - 00:42:42 - 00:48:54 - Articles referenced in episode: Brain–gut photobiomodulation restores cognitive alterations in chronically stressed mice through the regulation of Sirt1 and neuroinflammation   Methylene Blue Reduces Mortality in Critically Ill and Perioperative Patients: A Meta-Analysis of Randomized Trials A regulatory compliant short-term oral toxicity study of soluble [60]fullerenes in rats - Check out BioLight's two most popular Bundles!1.) The Mitochondrial Triad Bundle: For this bundle, you choose one of each: one BioBlue product, one BioC60 product and one red light therapy product and save 20% on the entire order!   2.) The BioBundle: For this bundle, choose your favorite BioBlue product and your favorite BioC60 product and save 15%! You can save an additional 10% buy subscribing to this bundle. That's correct, you can save a total of 25% via the BioBundle! - To learn more about red light therapy and shop for the highest-quality red light therapy, methylene blue & C60 products, visit https://www.biolight.shop - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn   BioLight: Website Instagram YouTube Facebook

Show notes at pharmacyjoe.com/episode934. In this episode, I'll discuss an article about using fondaparinux in critically ill patients with severe renal dysfunction. The post 934: Fondaparinux in critically ill patients with severe renal dysfunction appeared first on Pharmacy Joe.

DISCLAMER >>>>>>    The Ditch Lab Coat podcast serves solely for general informational purposes and does not serve as a substitute for professional medical services such as medicine or nursing. It does not establish a doctor/patient relationship, and the use of information from the podcast or linked materials is at the user's own risk. The content does not aim to replace professional medical advice, diagnosis, or treatment, and users should promptly seek guidance from healthcare professionals for any medical conditions.   >>>>>> The expressed opinions belong solely to the hosts and guests, and they do not necessarily reflect the views or opinions of the Hospitals, Clinics, Universities, or any other organization associated with the host or guests.       Disclosures: Ditch The Lab Coat podcast is produced by (Podkind.co) and is independent of Dr. Bonta's teaching and research roles at McMaster University, Temerty Faculty of Medicine and Queens University. Welcome to "Ditch the Lab Coat," the podcast where we dive deep into health issues and medical discussions with leading experts.In today's reflection episode, Dr. Bonta revisits some of the most insightful conversations from the past 19 episodes, touching on key topics in medical education, mentorship, and the evolving landscape of healthcare. Join us as Dr. Bonta delves into the value of ongoing mentorship, the importance of simulations, and the delicate balance of personal well-being for medical professionals. We'll explore the impact of AI in healthcare, the significance of end-of-life discussions, and the ongoing challenges of chronic disease management. Plus, we'll tackle pressing issues like children's mental health, the rise of screen time, and even some practical information about managing allergies. Whether you're a medical professional or just passionate about science-based skepticism in healthcare, this episode is packed with valuable insights. So, sit back, relax, and let's ditch the lab coat together.Timestamps : 05:31 Children need advocacy for voice and rights.08:28 Struggles at work, need to decompress.11:28 Obesity viewed as medical condition requiring compassion.13:08 Prepare for potential harm, seek professional help.16:02 Angiograms and heart procedures are routine, significant.21:56 Balancing screen use, health, and technology impact.24:01 Teaching simulation, heart surgery, martial arts comparison.27:41 Struggle to implement change, still highly beneficial.29:04 Accessible school routine for children and anxiety.31:39 Join Doctor Bonta for science-based health talk.

Contributor: Aaron Lessen MD Educational Pearls: The case: A gentleman came in from a nursing home with symptoms concerning for sepsis. He was hypotensive, hypoxic, febrile, and mentally altered. His past medical history included previous strokes which had left him with deficits for which he required a feeding tube. Initial workup included some point of care labs which revealed a sodium of 165 mEq/L (normal range 135-145) Hypernatremia What causes it? Dehydration, from insufficient fluid intake. This might happen in individuals who cannot drink water independently, such as infants, elderly, or disabled people, as was the case for this patient. Other causes of dehydration/hypernatremia include excessive sweating; diabetes insipidus; diuretic use; kidney dysfunction; and severe burns which can lead to fluid loss through the damaged skin. How do you correct it? Need to correct slowly, not more than 10 to 12 meq/L in 24 hours Can do normal saline (0.9%) or half saline (0.45%) and D5, at 150-200 mL per hour. Check the sodium frequently (every 2-3 hours) Will likely need ICU-level monitoring What happens if you correct it too quickly? Cerebral edema Seizures Bonus fact: Correction of hyponatremia too quickly causes osmotic demyelination syndrome (ODS). References Chauhan, K., Pattharanitima, P., Patel, N., Duffy, A., Saha, A., Chaudhary, K., Debnath, N., Van Vleck, T., Chan, L., Nadkarni, G. N., & Coca, S. G. (2019). Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients. Clinical journal of the American Society of Nephrology : CJASN, 14(5), 656–663. https://doi.org/10.2215/CJN.10640918 Lindner, G., & Funk, G. C. (2013). Hypernatremia in critically ill patients. Journal of critical care, 28(2), 216.e11–216.e2.16E20. https://doi.org/10.1016/j.jcrc.2012.05.001 Muhsin, S. A., & Mount, D. B. (2016). Diagnosis and treatment of hypernatremia. Best practice & research. Clinical endocrinology & metabolism, 30(2), 189–203. https://doi.org/10.1016/j.beem.2016.02.014 Summarized by Jeffrey Olson MS2 | Edited by Meg Joyce & Jorge Chalit, OMSIII

Show notes at pharmacyjoe.com/episode917. In this episode, I’ll discuss the impact of achieving an aggressive PK/PD target for beta lactams in critically ill patients. The post 917: What is the impact of achieving an aggressive PK/PD target for beta lactams in critically ill patients? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode914. In this episode, I’ll discuss oral vs IV phosphate replacement for critically ill patients with mild to moderate hypophosphatemia. The post 914: Does Oral Phosphate Replacement Work as Well as IV For Critically Ill Patients With Mild to Moderate Hypophosphatemia? appeared first on Pharmacy Joe.

Join Drs Andrea Sikora and Christy Forehand in the discussion of their recent work with using a medication regimen complexity score to evaluate potential relationships between the score and medication errors in the ICU setting. What they found was surprising. What is to come with future research is exciting. Read the full article here.

This episode of the CBIA BizCast is part one of a two-part discussion on a key issue in Connecticut and across the country— whole genome sequencing. In this episode Paul Pescatello, CBIA senior counsel and executive director of the Connecticut Bioscience Growth Council speaks with Dr. Tom Defay. Defay is a computational biologist and Deputy Head Diagnostics Strategy & Development at New Haven-based Alexion Pharmaceuticals, Inc. He details how the technology is valuable to patients for early diagnosis and treatment, and a cost saver for our healthcare system. This legislative session a bill to promote expansion of whole genome sequencing, HB 5367, An Act Concerning Medicaid Coverage of Rapid Whole Genome Sequencing for Critically Ill Patients, is before the Connecticut General Assembly. This is important legislation and it is strongly supported by the CBIA Bioscience Growth Council.

Dr. Linah Alqurashi, Ph.D., MS, RD, LDN, is a registered dietitian nutritionist with expertise in critical care nutrition and managing chronic disease.  She holds a doctorate in Nutritional Sciences from Howard University, Master of Science in Nutrition and Dietetics from the University of the District of Columbia in Washington DC, and Bachelor of Science in Clinical Nutrition from Umm-AL Qura University, Collegeof Applied Sciences in Saudi Arabia. Linah currently, works as a Clinical Dietitian and researcher at MedStar Washington Hospital Center. This episode was recorded on 2/4/24 and is hosted by Christina M. Rollins, MBA, MS, RDN, LDN, FAND, CNSC.

In this episode, we discuss the etiology of diaphragmatic dysfunction, its management and strategies for prevention. 

In this podcast, JPEN Editor-in-Chief Dr. Kenneth Christopher, interviews Dr. Alexandria Paige, an anesthetic registrar whose specific interest is in critical care nutrition at the Department of Anesthesia at Surrey and Sussex Healthcare NHS Trust in Redhill, England, and the first author of the research article “Association Between Calorie Surplus and ICU Length of Stay in Critically Ill Patients: A Retrospective Cohort Study”. Business Corporate by Alex Menco | alexmenco.net Music promoted by www.free-stock-music.com Creative Commons Attribution 3.0 Unported License creativecommons.org/licenses/by/3.0/deed.en_US February 2024

Show notes at pharmacyjoe.com/episode888. In this episode, I’ll discuss how fluid overload affects the pharmacokinetics of extended infusion meropenem in critically ill patients with sepsis. The post 888: The Effects of Fluid Overload On the Pharmacokinetics of Extended Infusion Meropenem in Critically Ill Patients with Sepsis appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode888. In this episode, I’ll discuss how fluid overload affects the pharmacokinetics of extended infusion meropenem in critically ill patients with sepsis. The post 888: The Effects of Fluid Overload On the Pharmacokinetics of Extended Infusion Meropenem in Critically Ill Patients with Sepsis appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode875. In this episode, I ll discuss whether diuretics are safe for reducing fluid balance in critically ill patients. The post 875: The Safety of Diuretics to Reduce Fluid Balance in Critically Ill Patients appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode875. In this episode, I'll discuss whether diuretics are safe for reducing fluid balance in critically ill patients. The post 875: The Safety of Diuretics to Reduce Fluid Balance in Critically Ill Patients appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode871. In this episode, I’ll discuss whether a nasal MRSA screen is useful for choosing antibiotics in critically ill patients with an intraabdominal infection. The post 871: Can a nasal MRSA screen be useful for choosing antibiotics in critically ill patients with an intra abdominal infection? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode871. In this episode, I’ll discuss whether a nasal MRSA screen is useful for choosing antibiotics in critically ill patients with an intraabdominal infection. The post 871: Can a nasal MRSA screen be useful for choosing antibiotics in critically ill patients with an intra abdominal infection? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode847. In this episode, I'll discuss a clinical prediction model for augmented renal clearance in adult mixed critically ill patients. The post 847: A Clinical Prediction Model for Augmented Renal Clearance in Adult Mixed Critically Ill Patients appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode847. In this episode, I ll discuss a clinical prediction model for augmented renal clearance in adult mixed critically ill patients. The post 847: A Clinical Prediction Model for Augmented Renal Clearance in Adult Mixed Critically Ill Patients appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode841. In this episode, I'll discuss 3 reasons to consider holding lithium in critically ill patients. The post 841: Should Lithium Be Resumed in Critically Ill Patients While Still in the ICU? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode841. In this episode, I ll discuss 3 reasons to consider holding lithium in critically ill patients. The post 841: Should Lithium Be Resumed in Critically Ill Patients While Still in the ICU? appeared first on Pharmacy Joe.

In this episode of the podcast, we will discuss oncologic emergencies. Dr. Zanotti is joined by Dr. R Scott Stephens, a pulmonary/critical care physician and associate professor of medicine and oncology at the Johns Hopkins University School of Medicine. He is the Director of Oncology and Bone Marrow Transplant Critical Care at Johns Hopkins Hospital and the Sidney Kimmel Comprehensive Cancer Center. A recognized clinician, educator, and researcher Dr. Stephens has expertise and interest in ARDS, ECMO, and oncologic critical care. Additional Resources: Oncologic Emergencies for the Intensivist – the Old, the New, and the Deadly. Thandra K, et al. J Intensive Care Med 2020: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886674/ Oncologic Emergencies – Traditional and Contemporary. Spring J, and Munshi L. Crit Care Clin 2020: https://pubmed.ncbi.nlm.nih.gov/33190777/ Critically Ill Patients with Cancer: A Clinical Perspective. Martos-Benitez F, et al. World J clin Onco 2020: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643188/ Management of Febrile Neutropenia: ESMO Clinical Practice Guidelines. Annals of Oncology 2016: https://www.annalsofoncology.org/article/S0923-7534(19)31643-6/pdf Books Mentioned in this Episode: The Elements of Style. By William Strunk and EB White: https://amzn.to/3KddG7C The Structure of Scientific Revolutions: By William Kuhn: https://bit.ly/43HkS34 The Physicists: The History of a Scientific Community in Modern America. By Daniel Kevles: https://bit.ly/477Z8jO American Prometheus: The Triumph and Tragedy of j. Robert Oppenheimer. By Kai Bird and Martin Sherwin: https://bit.ly/479AEqn

Have you ever gotten an IV nutrient drip? Tempted by the promises of better energy, clearer skin, clearing a hangover, or improving your immunity? Before you go out and spend hundreds of dollars on an IV drip at one of the trendy “drip bars”, you need to listen to this episode! We discuss the health claims and evidence (or lack thereof), risks and safety concerns, and whether or not we are on board with IV nutrient therapy.    In this episode, we discuss the buzzworthy trend of IV nutrient therapy. While it may sound promising to have a megadose of vitamins infused directly into your veins, there are some serious drawbacks and limitations to this type of infusion. Some nutrients in these infusions are in poor quality forms, while others are coupled with preservatives and parabens that may do more harm than good. Learn about risks and benefits, who should absolutely not get an IV drip, and why we prefer high quality oral supplementation.    Also in this episode: Live Keto Program Starts 9/6 - Early Bird $50 off with code EARLYBIRD50 What is IV Nutrient Therapy? Health Claims of IV Nutrient TherapyShort and long term treatment of asthma with intravenous nutrients | Nutrition Journal Intravenous Micronutrient Therapy (Myers' Cocktail) for Fibromyalgia: A Placebo-Controlled Pilot Study - PMCEpisode 321 Fibromyalgia Electrolyte Limeade What Nutrients are in IV Drips? What are Risks and Safety Concerns of IV Nutrient Therapy?IV Drips Bypass the Body's Natural Filters Infection Adverse Reactions Kidney Complications Fluid overload in the ICU: evaluation and management Are IV Nutrient Drips Effective?A Meta-analysis of Randomized Control Trials: The Impact of Vitamin C Supplementation on Serum CRP and Serum hs-CRP Concentrations Intravenous vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial Glutathione infusion before primary percutaneous coronary intervention: a randomised controlled pilot study The Effect of Intravenous Selenium on Oxidative Stress in Critically Ill Patients with Acute Respiratory Distress Syndrome Is there a role for oral or intravenous ascorbate (vitamin C) in treating patients with cancer? A systematic review Mortality in septic patients treated with vitamin C: a systematic meta-analysis Vitamin C Administration to the Critically Ill: A Systematic Review and Meta-Analysis Magnesium for skeletal muscle cramps Intravenous Magnesium Sulfate in Acute Stroke Why Oral Supplementation is SuperiorEpisode 177 Why You Need Supplements Part 1 Episode 178 Why You Need Supplements Part 2 B-12 Boost lozenge  B Complex Bio-C Plus vitamin C Cellular Antiox Relax and Regulate    Sponsors for this episode:  This episode is sponsored by Wild Foods, a company that puts quality, sustainability, and health first in all of their products. They have everything from coffee to turmeric to medicinal mushrooms, and every single product is painstakingly sourced from small farms around the globe. They take their mission seriously to fix the broken food system, and believe real food is medicine. They've partnered with us to give you guys an exclusive discount, so use the code ALIMILLERRD for 12% off your order at WildFoods.co!   

Show notes at pharmacyjoe.com/episode817. In this episode, I'll discuss how to predict failure of insulin transition in critically ill patients with diabetic ketoacidosis. The post 817: How to Predict Failure of Insulin Transition in Critically Ill Patients with Diabetic Ketoacidosis appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode817. In this episode, I ll discuss how to predict failure of insulin transition in critically ill patients with diabetic ketoacidosis. The post 817: How to Predict Failure of Insulin Transition in Critically Ill Patients with Diabetic Ketoacidosis appeared first on Pharmacy Joe.

Commentary by Dr. Valentin Fuster

ICU patients are at high risk for venous thromboembolism, and the majority of patients require prophylaxis. The challenging therapy is thrombocytopenia. Join host Geoff Wall, as he evaluates the results of a new study evaluating the clinical thresholds for chemical prophylaxis.The GameChangerThe majority of ICU patients eligible for VTE prophylaxis do not receive it. Different clinicians use different thresholds to initiate or stop prophylaxis. The database study discussed provides a potential evidence-based threshold.Show Segments00:00 - Introductions00:47 - VTE Prophylaxis Background09:34 - Looking at the Study18:42 - The GameChanger: A Potential Threshold for Chemical Prophylaxis22:15 - Connecting to Practice: Applicability26:13 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthReferences and ResourcesAssociation between Early Venous Thromboembolism Prophylaxis, Bleeding Risk, and Venous Thromboembolism among Critically Ill Patients with Thrombocytopenia. Redeem your CPE hereCPE (Pharmacist)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the history and use of VTE prophylaxis in the ICU2. Describe the results of the Pang et al study discussed and its applicability to ICU patients0.05 CEU/0.5 HrUAN: 0107-0000-23-134-H01-PInitial release date: 04/10/2023Expiration date: 04/10/2024Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Dr. Michael Lanspa chats with Dr. Yahya Shehabi about his article, "Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III)."

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Nina Andersen-Ranberg. They discuss her recent RCT published in the NEJM investigating haloperidol for delirium in ICU patients. Dr. Andersen-Ranberg is a physician undergoing her PhD training in Anesthesiology in Zealand University Hospital, Køge Denmark.

Episode 3! In this episode switch it up and review 2 NEW articles that published with SCCM 2023 1)"Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension" or CLOVERS by the PETAL Network published NEJM 2023 and 2) "Effect of Non-Invasive Ventilation After Extubation in Critically Ill Patients with Obesity in France" by De Jong et al published Lancet Respiratory medicine 2023. Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Alisa Higgins. They discuss long-term outcomes in critically ill patients with COVID-19. Dr. Higgins is Senior Research Fellow at Monash University in Melbourne, Australia.

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Yahya Shehabi. They discuss sedation with dexmedetomidine and propofol in critically ill patients. Dr. Shehabi is Professor of Medicine at Monash University (Australia).

Nikitha Yagnala, PharmD (@nikithayagnala) recognizes the physiologic consequences of sleep disturbances in critically ill patients, discusses the mechanisms of sleep promotion for pharmacologic sleep agents and outlines appropriate utilization of pharmacologic sleep agents in critically ill patients. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter! You can also connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the November 15, 2022, issue. Related Content: Audio Highlights

I have the privilege of talking with Nicole Langton- Frost, MA, CCC-SLP, BCS-S about her experience as an acute SLP who is now working in an administration role while maintaining a clinical role in the ICU and partnering with her research colleagues at Johns Hopkins. The post 232 – I See You: The Challenging Role of the SLP in Critically Ill Patients – Nicole Langton-Frost, MA, CCC-SLP, BCS-S appeared first on Swallow Your Pride Podcast.

I have the privilege of talking with Nicole Langton- Frost, MA, CCC-SLP, BCS-S about her experience as an acute SLP who is now working in an administration role while maintaining a clinical role in the ICU and partnering with her research colleagues at Johns Hopkins. The post 232 – I See You: The Challenging Role of the SLP in Critically Ill Patients – Nicole Langton-Frost, MA, CCC-SLP, BCS-S appeared first on Swallow Your Pride Podcast.

Chapter 7ReferencesSands JM, Blount MA and Klein JD. Regulation of Renal Urea Transport by Vasopressin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116377/In this invited piece, Sands and colleagues explain that although urea is permeable across membranes, this is slow, thus urea transporters in the kidney, under control of vasopressin, are needed to facilitate transport and create the medullary gradient. Text book using 20% of extracellular compartment being in the intravascular compartment. https://courses.lumenlearning.com/ap2/chapter/body-fluids-and-fluid-compartments-no-content/ another one: https://med.libretexts.org/Bookshelves/Anatomy_and_Physiology/Book%3A_Anatomy_and_Physiology_(Boundless)/25%3A_Body_Fluids_and_Acid-Base_Balance/25.2%3A_Body_Fluids/25.2B%3A_Fluid_Compartments The chapter I wrote where I went through the math in figure 7-3. It was a major revelation to me: https://docs.google.com/document/d/17BM1xihvlztuQlU8GVNhEDoPLzr6GounHYZAtVUkLvw/edit?usp=sharing Association Between ICU-Acquired Hypernatremia and In-Hospital Mortality https://journals.lww.com/ccejournal/fulltext/2020/12000/association_between_icu_acquired_hypernatremia_and.26.aspx Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients https://pubmed.ncbi.nlm.nih.gov/30948456/ Edelman IS, Leibman J, O'Meara MP and Birkenfeld LW. Interrelations between serum sodium concentration, serum osmolarity and total exchangeable sodium, total exchangeable potassium and total body water. JCI 1958. This classic paper calculates the total body exchangeable sodium and potassium and establishes the relationship between these. Understanding this painstacking work helps understand the effect of supplementing potassium in the setting of hyponatremia. https://dm5migu4zj3pb.cloudfront.net/manuscripts/103000/103712/cache/103712.1-20201218131357-covered-e0fd13ba177f913fd3156f593ead4cfd.pdfEdelman is the Root of Almost All Good in Nephrology https://www.renalfellow.org/2014/11/20/edelman-is-root-of-almost-all-good-in/ Jens Titze and his team published a pair of articles that shocked those interested in salt and water in JCI in 2017. High Salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation https://www.jci.org/articles/view/88532Increased salt consumption induces body water conservation and decreases fluid intake https://www.jci.org/articles/view/88530in this exciting exploration of the basic assumptions that we hold true regarding salt and water (and staring Russian cosmonauts and an incredible controlled simulation of salt and water intake), Titze shows that high sodium intake does not simply drive water consumption (as we usually teach) but instead leads to a complex hormonal and metabolic response (even with diurnal variation!) and results in body water conservation and decreased water consumption. And accompanying editorial from Mark Zeidel: salt and water, not so simple. https://www.jci.org/articles/view/94004In addition, Titze and others have done interesting work on sodium deposition in tissues where it may also be a source for systemic inflammation.https://pubmed.ncbi.nlm.nih.gov/28154199/Jens Titze talking about salt, water, thirsting a TEDx talk. https://www.youtube.com/watch?v=jQQPBmnIuCY A discussion/debate of the overfill vs. underfill theory of edema in the nephrotic syndrome (hint- overfill theory triumphs) would be incomplete without a reference to congenital analbuminemia. This reference from Frontiers in Genetics explores the diagnosis, phenotype and molecular genetics and reveal that patients tend to have only mild edema but severe hyperlipidemia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478806/The finding that proteinuria can directly lead to sodium retention based on a study when puromycin aminoglycoside induced proteinuria of one kidney lead to sodium retention by that kidney which was localized to the distal nephron. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC436841/?page=9Plasmin may be the culprit at the level of the epithelial sodium channel based on Tom Kleyman's work: https://jasn.asnjournals.org/content/20/2/233Amiloride may help! (stay tuned for amiloride in a future episode) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016639/An old favorite of JC's from the Kidney International feature which debates the cause of edema in the nephrotic syndrome.https://www.sciencedirect.com/science/article/pii/S0085253815583075Under protest, we hobbled through a discussion of the Gibbs Donnan affect even encouraged by one of Amy's fellows based on this article from QJM: https://academic.oup.com/qjmed/article/101/10/827/1520972 suggesting that our understanding of the role of hyponatremia in fractures might be all wrong- it could be related to hypoalbuminemia.

Show notes at pharmacyjoe.com/episode702. In this episode, I'll discuss the risk factors associated with the development of venous thromboembolism in ICU patients. The post 702: Risk Factors Associated With the Development of Venous Thromboembolism in Critically Ill Patients appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode693. In this episode, I'll discuss an article about using fondaparinux in critically ill patients with severe renal dysfunction. The post 693: Fondaparinux in critically ill patients with severe renal dysfunction appeared first on Pharmacy Joe.