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Thanks to Precision Fuel & Hydration for sponsoring this video! Get 15% off your first order at http://visit.pfandh.com/extramilestshow Katja shares the lessons how she went from a complete beginner to an experienced runner, how low heart rate training became a game changer, and ways to reach breakthroughs in your running and life. Watch the full video on YouTube Chapters: 0:00 — From Couch to 4 World Marathon Majors After 40 2:56 — When running first became meaningful 4:00 — Finding community through running 9:25 — The moment everything finally clicked in her training 10:48 — The breakthrough that made Katja faster 14:02 — How to race your best when everything goes wrong 16:31 — Precision Fuel and Hydration sponsorship 17:43 — The PR-or-bust racing approach 22:06 — Katja's journey with low heart rate training 24:53 — How to find your easy heart rate zone 25:55 — Why low intensity helps runners build safely 33:34 — Recovery from 50–60 mile weeks 37:44 — Why fueling properly improves recovery 39:48 — 90–100g of carbs per hour 44:09 — Sodium, hydration, and marathon fueling strategy 49:32 — Advice for new runners just starting out 53:55 — Why age shouldn't limit your running 56:09 — Strength training, mantras, and racing mindset 58:43— Learning to embrace the pain cave 1:04:23 — How to stay motivated and consistent 1:06:58 — Tommy Rivers at the NY Marathon 1:09:32 — Why running is about more than finish times 1:13:16 — Where to find Katja 1:14:00 — How to become a stronger, healthier, happier athlete 1:15:04 — What's next for Katja 1:15:47 — The mindset that keeps you improving as a runner Affiliate Disclosure: I may earn commissions if you purchase items via my affiliate links. "As an Amazon Associate I earn from qualifying purchases." Affiliate links do not increase cost to you. Also, you do not need to use these links. You can also search for these same items in Amazon or on any search engine/shopping site of your choice and buy/research them that way. FIND KATJA: ► INSTAGRAM: https://www.instagram.com/katja_bluemoon/ ► FACEBOOK: https://www.facebook.com/KatjaSnaps ► STRAVA: https://www.strava.com/athletes/65443975 LINKS & TOOLS MENTIONED: ► My Personal Best Running Coaching Program: https://www.skool.com/personalbest ► Precision Fuel and Hydration (Get 15% off your first order): http://visit.pfandh.com/extramilestshow ► Buy my new book Running Breakthroughs: https://geni.us/running-breakthroughs ► Jakob Ingebrigtsen Episode: https://www.youtube.com/watch?v=OQeh_Pg0Nz0 YOU CAN FIND ME, FLORIS GIERMAN HERE: ► Podcast: https://extramilest.com/podcast ► Strava: https://www.strava.com/athletes/1329785 ► Instagram: https://www.instagram.com/florisgierman ► Extramilest Website: https://extramilest.com ► Path Projects Website: https://pathprojects.com ABOUT THE EXTRAMILEST SHOW: A podcast and YouTube channel where host Floris Gierman interviews world class athletes, coaches and health experts on the topic of how to become a stronger, healthier and happier athlete. More info about our running coaching program can be found at https://www.skool.com/personalbest. Subscribe and hit the bell to see new videos: https://bit.ly/Flo-YT #Running #MarathonTraining #RunningMotivation #HalfMarathon #marathon #zone2
The $100,000 H-1b visa fee landed in September 2025 like a fire alarm in the hallways of medicine—hospitals panicked, advocacy groups mobilized, and a lot of people predicted the international resident pipeline would collapse. Dr. Bryan Carmody, The Sheriff of Sodium rejoins co-hosts David Lee, Mukund Viswanadha, and Isa Perez-Sandi to ask the question nobody was asking: was the panic grounded in reality? More interesting to think about: why rural physician shortages are a compensation and incentive problem, not a numbers problem; why loan forgiveness alone probably isn't moving the needle; and what separates effective physician advocacy from "just expressing emotion and hoping facts do the work." Then graduating high-school listener Aditi asks whether community college is a viable launch pad for medicine.
Marty checks in 26 days out from the Gold Coast Marathon to discuss his peak marathon training, achilles niggle, biggest long run yet, fueling plan including sodium loading, race weight, sauna, strength work, and shoe choice. Marty Bordignon Instagram: https://www.instagram.com/martybordignon/ Marty Bordignon Strava: https://www.strava.com/athletes/martybordignon/ Marty Bordignon Podcast: https://open.spotify.com/user/martyb-au?si=sgXyMAYERJGyKdGCYeXTUw Train with Matt: https://sweatelitecoaching.com/matt-fox/ Private Podcast Feed + Discord: https://www.sweatelite.co/shareholders/ Contact Matt: matt@sweatelite.co Matt Fox Instagram: https://www.instagram.com/mattinglisfox/ Matt Fox Strava Training Log: https://www.strava.com/athletes/6248359/ With 26 days until the Gold Coast Marathon, Matt and Marty review Marty's peak marathon build, including a 36.36 km long run averaging 4:07/km with 22.57 km at 3:46/km, faster than his current 2:46 PB pace. Marty explains that the run felt hard partly due to early Achilles tightness, which flared after stopping, and he reflects on whether he could have extended the marathon-effort segment closer to 30 km. The conversation covers Marty's confidence around breaking 2:40, his doubts about holding 3:45/km on race day, and his estimate of around a 30% chance if everything comes together. Matt and Marty also discuss his weekly mileage rising toward roughly 160 km, a strong 2 km "on" / 1 km float session, and the mental benefits and drawbacks of group training, Strava comparison, and chasing other runners' sessions. They also talk through Marty's current race weight of around 66.5 kg, his plan to take 100 g of carbohydrates per hour, heavy sodium loading to reduce cramping risk, minimal fluids, and possible beetroot and bicarb trials. Marty shares that he has neglected sauna and strength work since moving but may add heat sessions back in, while Matt and Marty debate sauna protocols, strength training tradeoffs, and whether the Puma FastR is the right race-day shoe despite Achilles concerns. Timestamps: 00:00 - Marathon Build Check In 01:06 - Big Long Run Breakdown 02:54 - Achilles Scare And Effort 05:45 - Confidence And Goal Pace Doubts 09:37 - Mileage Ramp And Consistency 11:01 - Float Session Fitness Boost 12:28 - Group Training And Strava Mind Games 15:25 - Sauna Plans And Heat Protocol 19:14 - Strength Training Debate 25:30 - Race Weight And Nutrition Update 27:00 - Elite Weight Targets Story 28:19 - George's Weight Cut 29:02 - Comrades Race Preview 29:46 - Chasing Race Weight 31:06 - Gold Coast Fuel Plan 33:42 - Hydration and Cramping 35:04 - Beetroot and Bicarb 38:26 - Shoe Choice Debate 41:42 - New Shoes and Kit 43:43 - Wrap Up and Next Episode
A quick scan of a pre-race warmup area and you'll see a rainbow array of brightly coloured drink mixes filling the bottles, beakers, and hydration packs of endurance athletes. For many, these beverages are the bridge between the hydration needs of “normal” people and the performance necessities of athletes, with brands touting optimized mineral blends and special formulas aimed at keeping athletes running harder for longer. But how much are these drinks really doing for performance and how much is clever marketing aimed at capitalizing on the most basic of human needs: thirst? With the hottest months upon us and the racing season in full swing, we welcome back Registered Dietitian Sandra Frail to dive into the salty waters of endurance hydration. We're taking a look at what our bodies really need to perform at their best, debunking some of the common misconceptions around electrolytes, sweat, and dehydration, and understanding the real-world strategies athletes can use to optimize their hydration and avoid pouring away extra money on pricey pee. Subscribe to The Shakeout Podcast feed on Apple, Spotify, YouTube or wherever you find your podcasts. Follow Sandra @nosweatnutrition McCubbin Journal Article: Sodium intake for athletes before, during and after exercise: review and recommendations Push past the finish line with nutrition that fuels you. CanPrev is proudly Canadian and has been delivering supportive natural health supplements for over two decades. Whether you're training for your next goal race or looking to maximize performance when the gun goes off, make CanPrev's top-quality products part of your well rounded nutrition plan. Discover more at canprev.ca
A single line on a label can shake an entire trade, especially when that trade has been using the product for 30 plus years. We pick back up with Scott Hamilton, the CEO of United Chemical, to sort out what the EPA's “not for use in outdoor pools” language is really responding to, and whether the bromate concern is being evaluated in a way that matches real pool conditions.We get into the chemistry behind bromate exposure, including why some researchers argue it should not be assessed with a strictly linear model. Scott explains the case for looking at thresholds and real-world dose, plus the research showing how stomach acid can reduce a large portion of trace bromate back into bromide. We also talk about what makes the EPA process move slowly: protocol review, data acceptance, and the very real staffing and workload constraints that can turn a decision into a multi-year timeline.Then we zoom out to the business and legal side of pool chemical regulation. Why do some products stop claiming they “kill algae” even when pros swear they work? Because pesticidal claims trigger registrations, state-by-state fees, and a compliance burden that can be brutal. We also address the fear factor directly, how to think about risk tolerance, and why transparency matters when the manufacturer has a stake in the outcome. If you want to judge the study for yourself, we point you to the download link.Subscribe for more pool industry deep dives, share this with a tech who's debating sodium bromide, and leave a review with your take: should outdoor pool labeling follow worst-case assumptions or field-relevant data?We keep talking with Scott Hamilton about the EPA's interim stance on sodium bromide labels and what the latest bromate data actually says about real-world risk. We weigh the science, the legal reality of pesticidal claims, and why transparency matters when pool pros have relied on a product for decades. • how bromate exposure is being modeled and why linear risk assumptions may not fit real pool use • what research says about stomach acid reducing trace bromate back to bromide • how the EPA makes interim decisions and what it would take to revisit or reverse them • why some manufacturers remove algae-kill claims and how registration fees shape labels • how to think about risk tolerance alongside other common pool industry hazards • why publishing methods and raw data helps the industry move past rumors If you'd like to see a copy of the study, there's going to be a link in this podcast description for you. You can download that study and read it for yourself. If you're looking for part one, again go to my website, swimmingprolearning.com, click on the podcast icon, and open a drop-down menu of other podcasts that I've done before. If you're interested in the coaching program, you can learn more at PoolGuyCoaching.com. Download the full Sodium Bromide Study:https://drive.google.com/file/d/1X6-1uJJ7MZugeRDpch0tpop2vg0hjPR0/view?usp=sharingSend us Fan MailSupport the Pool Guy Podcast Show Sponsors! HASA https://bit.ly/HASAThe Bottom Feeder. Save $100 with Code: DVB100https://store.thebottomfeeder.com/Try Skimmer FREE for 30 days:https://getskimmer.com/poolguy Get UPA Liability Insurance $64 a month! https://forms.gle/F9YoTWNQ8WnvT4QBAPool Guy Coaching: https://bit.ly/40wFE6y
Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember
The EPA's sodium bromide relabeling decision didn't just tweak a bottle panel, it pulled a familiar algae treatment tool out of the outdoor pool conversation overnight. We're joined by Scott Hamilton, the CEO of United Chemical to explain what the EPA's interim decision actually says, why “not for use in outdoor pools” now shows up on sodium bromide-based algaecides, and how that single change ripples through distribution when big suppliers decide they won't stock the category at all. From there, we get practical and technical. Scott walks us through worst-case outdoor testing designed to stress the chemistry: high pH, zero cyanuric acid (CYA), and heavy liquid chlorine dosing in above-ground pools. We talk bromate formation, why the EPA leans on conservative assumptions like 100% conversion, and what the real-world data shows instead, including the striking difference between treating a pool with active algae versus clean water. If you've ever wondered why timing matters, we dig into the “first hour” window where most bromate formation tends to occur and what actually drives the reaction. We also zoom out to risk, regulation, and perception: how Prop 65 style warning logic shapes the conversation, how the EPA swim model estimates ingestion exposure over a lifetime, and the question every pool pro asks, why hot tubs still get a pass while outdoor pools don't. Subscribe for part two, share this with a pool pro who's navigating algae season, and leave a review with your take on the ruling.We sit down with Scott Hamilton from United Chemical to unpack the EPA's interim decision that forces sodium bromide products to remove outdoor pool use from their labels and triggers major supply chain fallout. We dig into bromate formation, what worst-case testing actually shows, and why the first hour after dosing becomes the key battleground in the chemistry debate. • who the interim decision affects and why labels now read not for outdoor pools • why Pool Corp and others stop carrying sodium bromide products • how the EPA reaches decisions when it does not run its own controlled lab tests • worst-case outdoor testing design using high pH, zero CYA, and heavy liquid chlorine • what the data shows with algae present versus clean water • why most bromate formation happens in the first hour • how proprietary ingredients can suppress bromate formation • how Prop 65 and linear risk models shape public perception • why hot tubs get treated differently under the EPA exposure assumptions Are you a pool service pro looking to take your business to the next level? Join the pool guy coaching program. Learn more at Swimmypoollearning.com. If you're interested in the coaching program that I offer, you can learn more at ProGuideCoaching.com. Download the full Sodium Bromide Study:https://drive.google.com/file/d/1X6-1uJJ7MZugeRDpch0tpop2vg0hjPR0/view?usp=sharingSend us Fan MailSupport the Pool Guy Podcast Show Sponsors! HASA https://bit.ly/HASAThe Bottom Feeder. Save $100 with Code: DVB100https://store.thebottomfeeder.com/Try Skimmer FREE for 30 days:https://getskimmer.com/poolguy Get UPA Liability Insurance $64 a month! https://forms.gle/F9YoTWNQ8WnvT4QBAPool Guy Coaching: https://bit.ly/40wFE6y
Jax Siddall - highly competitive American distance runner and educator. Jax recently smashed the Eugene Marathon men's course record, running 2:15:02 and securing an Olympic Trials Qualifying time in his very first attempt at the 26.2-mile distance. Jax and Cam cover what it took in training and preparation for Jax to qualify for the Olympic Trials, fueling strategies, running shoe differences, and more! Follow Jax: https://www.instagram.com/jaxpsiddall Follow along: Instagram: https://www.instagram.com/cameronrhanes Twitter: https://twitter.com/cameronhanes Facebook: https://www.facebook.com/camhanes/ Website: https://www.cameronhanes.com Timestamps: 00:00:00 – Qualifying for the Olympic Trials and Moving to Eugene, OR 00:05:45 – Training for Beating the Record 00:13:08 – Eugene Marathon: The Mindset in Achieving a Time of 02:10: 00:18:52 – The Golden Standard in Running: 26.2 Miles 00:23:34 – A Love for Running at a Young Age 00:30:53 – Training, Raising Hemoglobin, Sponsors, & a Career in Teaching 00:33:52 – Teaching Social Studies, the Netherlands, & Different Cultural Differences 00:43:04 – People that Jax Looks up to 00:50:01 – Running Documentaries on YouTube 00:53:16 – Surges During Marathon Races & Pulling the Group 00:57:10 – Fueling Strategy: Gels, Carbs, and Sodium for Races 01:01:44 – Training with Carbon Plated Running Shoes 01:08:12 – What's Next: Broken Arrow 23k 01:12:16 – Treadmill Training for Speed and Elevation 01:16:22 – Keeping the Belief: Initial Failure in Competing to Qualify for the Olympic Trials 01:19:43 – Strategic Race Selection: Finding Stronger Competition 01:21:26 – Future Plans in Running & the Olympics 01:23:47 – Final Thoughts Thank you to our sponsors: Sig Sauer: https://www.sigsauer.com/ use code CAM10 for 10% off optics LMNT: Visit https://drinklmnt.com/cam for a free sample pack with any purchase Hoyt: http://bit.ly/3Zdamyv use code CAM for 10% off Ketone IQ: https://www.ketone.com/Cam use code CAM for 30% off your first subscription Montana Knife Company: https://www.montanaknifecompany.com/ Use code CAM for 10% off Grizzly Coolers: https://www.grizzlycoolers.com/ use code KEEPHAMMERING for 20% off
In this episode, Lucas Aoun interviews Jay Feldman, a leading voice in bioenergetics and cellular health. They explore how optimizing cellular energy impacts sleep, hormones, and overall health, delving into topics like carbohydrate types, gut health, bile flow, and the importance of sodium and sugar in human physiology.Relevant links:Jay Feldman's Website: https://www.jayfeldmanwellness.com/ Chapters: 00:00 Introduction to Bioenergetics and Health00:58 Jay Feldman's Journey into Nutrition02:46 The Bioenergetic View of Health04:32 Exploring Starch and Its Effects10:13 Personal Experiences with Starch Sensitivity15:26 Understanding Digestion and Its Hidden Factors18:37 The Role of Bile and Tudca in Health22:26 The Importance of Sodium in Nutrition24:16 The Importance of Sodium in Diet27:43 Understanding Sugar's Role in Energy Production29:24 The Carbohydrate vs. Fat Debate35:34 Optimizing Sleep for Energy Production42:16 Essential Foods for Optimal VitalityDisclaimer:The information provided in this podcast episode is for entertainment purposes and is NOT MEDICAL ADVICE. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Aoun and is for informational and entertainment purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. Neither Lucas Aoun nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this content. All consumers of this content especially taking prescription or over-the-counter medications should consult their physician before beginning any nutritional, supplement or lifestyle program. Hosted on Acast. See acast.com/privacy for more information.
This week we kicked things off with Eric's experience crewing for Heather Jackson at Unbound XL, 350 miles of gravel, mud, and racing through the night. Josh Amberger also made a stunning gravel debut with a fourth-place finish, and we had some thoughts on that. Then we went through listener questions. We also talked the Escape from Alcatraz donut run, compression shorts, and the best perks of being a pro athlete (or pro athlete adjacent). This week we discussed:Eric supporting Heather Jackson at Unbound XL and Josh Amberger's surprise fourth-place finishWhat it's like when podcast listeners know more about you than you know about themPanicking in an open water swim and how to recover your composure mid-raceOff-road triathlon etiquette, do you have to stop and let faster riders pass?Racing a tri bike you've never ridden before: smart gamble or bad idea?Mile repeats vs. kilometer repeats, does interval length actually matter?Sodium and cramping: preloading, in-race electrolytesWearing compression shorts under your bibsWill 32-inch wheels ever make it into triathlon?Favorite perks of being a professional (or pro-adjacent) triathleteA big thank you to our podcast supporters who keep the podcast alive! To submit a question for the podcast and to become a podcast supporter, head over to ThatTriathlonLife.com/podcast
Put salt (aka sodium chloride) in your pasta water and you'll end up with delicious spaghetti. Put pure sodium in it instead… and it will explode. It's the latest edition of “The Element of Surprise,” our occasional series about the hidden stories behind the periodic table's most unassuming atoms, isotopes, and molecules. This time we're talking all about sodium. It's the periodic table's saltiest element. It powers your body like a battery and you need it to survive. So why is too much of it bad for you? Plus, how did salt help the North win the Civil War? Featuring Raychelle Burks, Trisha Pasricha, Ashley Dumas. Produced by Felix Poon. For full credits and transcript, visit outsideinradio.org. SUPPORT Outside/In is made possible with listener support. Click here to become a sustaining member of Outside/In. Follow Outside/In on Instagram or join our private discussion group on Facebook. LINKS Watch a 1947 newsreel of the US Army disposing thousands of pounds of pure sodium into a lake in Washington State, causing massive explosions. See images of the Slanic Salt Mine in Romania and the Wieliczka Salt Mine in Poland, now major tourist sites. Check out Theodore Gray's “Sodium Party” YouTube video series where he drops sodium chunks of various sizes into water to observe how they explode. Here's the first video in the series.Want to learn more about the role of salt throughout human history? Read Mark Kurlansky's Salt: A World History. Learn more about your ad choices. Visit megaphone.fm/adchoices
[00:00] - Intro [00:51] - Researching alkalinity since 2016 [05:27] - CYA contributes to TA, so does acid reduce CYA? [07:09] - Acid vs. Bicarbonate Reaction [09:08] - Sodium and Chlorides are Spectator ions [12:10] - Does acid burn through Cyanurate Alkalinity too? [15:04] - What about chlorinated isocyanurates? [17:20] - Closing ______________________________Connect with us! Realize your full potential.Watershape University®Water chemistry questions?Orenda®Questions? Comments? Or apply to sponsor the show:ruleyourpool@gmail.com Facebook: @ruleyourpoolYouTube: @rule-your-pool
SpaceTime with Stuart Gary | Astronomy, Space & Science News
SpaceTime Series 29 Episode 65 *NASA confirms its moon base plans and first contracts NASA confirms its plans to have humans living on the Moon by 2032. The agency has released the latest draft of its lunar south pole base project and signed its first contracts. *A surprising core reversal deep inside the Earth The European Space Agency has discovered a mysterious flow reversal of Earth liquid iron outer core. *Red dwarf stars detected 'eating' Earth-like planets Astronomers have discovered some of the strongest evidence yet that stars eat their offspring. *The Science Report The healthy tomato-soy juice cocktail that could lower inflammatory proteins. A new species of giant mosasaur fossil discovered in Texas. Sodium-ion batteries could become a genuine low-cost rival to lithium-ion technology. Skeptics guide to secret flying saucers hidden in plain sight. Our Guests This Week: NASA Administrator Jared Isaacman NASA Associate Administrator Lori Glaze NASA Moon Base executive Carlos García-Galán And our regular guests: Alex Zaharov-Reutt from techadvice.life Tim Mendham from Australian Skeptics And Senior science writer and Sky and Telescope magazine contributor Jonathan Nally
Blood Sweat & Gear with Coaches Skip Hill Scott McNally breaks down the destabilization of the underground Growth Hormone market, possible China and US customs crackdowns, and what it means for bodybuilding in 2026. We also cover GH dosing, recovery, sodium and electrolyte balance, training age, cycle support, NAD+ experiences and real-world bodybuilding problem solving. 0:00 Underground HGH Crisis in 2026 – China or US Customs? 0:50 Generic Growth Hormone Market Destabilization 3:20 3 Reasons the Underground GH Market Is Breaking 10:00 Generic HGH vs Pharma HGH – Water Retention Differences 17:00 Best HGH Dosing Frequency for Bodybuilding in 2026 21:20 All-In-One Cycle Support Supplements 26:25 Recovery Changes With Training Age 31:00 Bulk or Cut? What To Do When You Lack Muscle Mass 34:30 Staying Lean but Still Looking “Baby Faced” 38:30 How Bodybuilders Survive Extreme Heat Waves 41:45 Sodium, Electrolytes and Hydration for Bodybuilders 49:20 Scott McNally's NAD+ Experience 51:40 When Your Bodybuilding Coach Isn't Plugged In 1:04:45 Skip's Word of the Day 1:09:00 Behind the Scenes
Une nouvelle étude montre un lien de plus en plus clair entre la consommation d’aliments ultra-transformés et l’augmentation des risques de démence. Entrevue avec Anne-Julie Tessier, professeure adjointe à l’Université de Montréal spécialisé sur l'impact de la nutrition sur la longévité en santé. Regardez aussi cette discussion en vidéo via https://www.qub.ca/videos ou en vous abonnant à QUB télé : https://www.tvaplus.ca/qub ou sur la chaîne YouTube QUB https://www.youtube.com/@qub_radio Pour de l'information concernant l'utilisation de vos données personnelles - https://omnystudio.com/policies/listener/fr
AI is moving from chatbots to agents, batteries are getting cheaper and longer-lasting, and China is emerging as a serious innovation engine across EVs, robotics and autonomous driving. Loftus Peak's Anshu Sharma joins Bryce and Ren to unpack where disruption is accelerating, how investors can separate hype from real revenue, and why the best opportunities may still be early.In this episode:00:00 Cheaper to hire a human than to use AI? 01:51 What's changed since Anshu was last on 03:50 The third AI inflection point explained 06:26 Are we still early in the AI investment cycle? 08:05 The warning signs of an AI bubble 11:28 Why most investors get disruption wrong 16:36 How Loftus finds the best company in a trend 19:37 Humanoid robots: hype or reality? 24:56 Inside China's robotics ecosystem 26:11 Beijing Auto Show: the battery that changed his mind 27:52 Sodium-ion batteries and the next leg of EVs 32:01 So where does Tesla fit in now? 36:55 Knowing when to sell a disruptive stock39:08 Why Loftus has been in and out of NVIDIA 4 times 42:28 Anshu's best company ever, book pick and adviceETFs and Stocks mentioned: Loftus Peak Global Disruption Fund (ASX: LPGD), Loftus Peak Global Disruption Fund Unhedged (ASX: LPJD), NVIDIA (NASDAQ: NVDA), Eli Lilly (NYSE: LLY), Datadog (NASDAQ: DDOG), Samsara (NYSE: IOT), Meta Platforms (NASDAQ: META), Tencent (HKEX: 0700), CATL (SZSE: 300750), BYD (HKEX: 1211), Tesla (NASDAQ: TSLA), WeRide (NASDAQ: WRD), Apple (NASDAQ: AAPL), Intel (NASDAQ: INTC), Taiwan Semiconductor Manufacturing Company (NYSE: TSM), Alphabet (NASDAQ: GOOGL), Microsoft (NASDAQ: MSFT), Amazon (NASDAQ: AMZN)Recommendations: The Thinking Machine: Jensen Huang, Nvidia and the World's Most Coveted MicrochipThis episode has been sponsored by Loftus Peak.Support from partners like Loftus Peak help us keep all our content free.If you want to learn more about Loftus Peak's Global Disruption active ETF (ASX: LPGD) head here.———Want to get involved in the podcast? Record a voice note or send us a messageAnd come and join the conversation in the Equity Mates Facebook Discussion Group.———Want more Equity Mates? Across books, podcasts, video and email, however you want to learn about investing – we've got you covered.Keep up with the news moving markets with our daily newsletter and podcast (Apple | Spotify)We're particularly excited to share our latest show: Basis PointsListen to the podcast (Apple | Spotify)Watch on YouTubeRead the monthly email———Looking for some of our favourite research tools?Download our free Basics of ETF handbookOr our free 4-step stock checklistFind company information on TIKRResearch reports from Good ResearchTrack your portfolio with Sharesight———Equity Mates Investing is a product of Equity Mates Media. Hosted on Acast. See acast.com/privacy for more information.
Episode Highlights With KatieHow all minerals form your body's electrical fieldWhy minerals are the foundation for hormones, sleep, detox, digestion & moodThe 4 layers of the Mineral Matrix: Sodium = the chargerPotassium = the stabilizerMagnesium = the conductorHumic/Fulvic = the activatorsHow mineral depletion affects blood sugar, stress, PMS, and metabolismWhy modern life drains minerals faster than any time in historyHow minerals determine your state of fight, flight, or restThe symphony analogy: why you need all the minerals, not just oneHow minerals increase cell voltage and make healing possibleYour personal mineral routine: what you use daily and whyHow mineral replenishment becomes a powerful safety signal for the bodyWhy rebuilding minerals is one of the fastest ways to feel betterResources MentionedSalt I useMagnesium Breakthrough supplementBEAM mineralsThe Body Electric - bookMicroplastics In Salt and How to Avoid ThemMitochondrial Mastery course from Justine StengerLMNT electrolytesSalt tabletsLMNTI talk often about the health benefits of salt and electrolytes and I am a big fan of LMNT canned drinks and packets. Go to drinklmnt.com/wellnessmana for a special offer.Just Thrive:Just Thrive Health has been one of my longtime favorite brands for gut health and they have an amazing Daily Gut Detox. Your immune system, gut barrier, and digestion get the support they need to stay strong and healthy. You can find this and their probiotics at justthrivehealth.com/wellnessmama or use code wellnessmama for 20% off your order.
On this episode of Vitality Radio, Jared takes on a viral video claiming that electrolyte supplements are nothing more than “dehydrated soda” and a wellness scam. In this Vitality Verdict, he separates legitimate concerns about influencer marketing and poor formulations from the physiology of hydration and mineral balance. Jared explains why sodium, potassium, and magnesium remain foundational nutrients, especially for people who exercise, fast, eat low-carb diets, drink coffee, use saunas, or live under chronic stress. He also addresses the misleading use of vitamin B6 toxicity to condemn an entire category of products. The bottom line: electrolytes are neither a scam nor a magic bullet. When used intelligently and in the right context, they can be a practical tool to support hydration, energy, muscle function, and overall vitality. Products:Re-Lyte ElectrolytesJust Ingredients ElectrolytesPowder Vitamin ElectrolytesGreat Naturally ElectrolytesVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
China is scaling sodium-ion batteries while Trump's fossil-fuel politics leave America behind in clean energy, grid storage, and the next manufacturing boom.Subscribe to our Newsletter:https://politicsdoneright.com/newsletterPurchase our Books: As I See It: https://amzn.to/3XpvW5o How To Make AmericaUtopia: https://amzn.to/3VKVFnG It's Worth It: https://amzn.to/3VFByXP Lose Weight And BeFit Now: https://amzn.to/3xiQK3K Tribulations of anAfro-Latino Caribbean man: https://amzn.to/4c09rbE
New Yorkers who have 16 or more speeding violations will now have to install a GPS device in their cars. Governor Kathy Hochul said it will stop motorists from speeding and make our roads safer. WFUV's Sonia Weliwitigoda reports on the push for more transparency on nutrition, involving two new bills that demand warning labels next to food items on certain restaurant menus. WFUV's Xenia Gonikberg breaks down the recent push to expand ranked-choice voting to general elections Governor Hochul announced reforms that will lower auto insurance rates for New Yorkers. WFUV's Sienna Reinders reports. WFUV's Alexandra Pfau sits down with Margaret Kaufer, the co-founder and president of the Stem Alliance, an organization that works to make technology accessible to everyone. Host/Producer: Livia Regina Editor: Lainey Nguyen Editor: Robin Shannon Editor: Nathan Ray Reporter: Sonia Weliwitigoda Reporter: Xenia Gonikberg Reporter: Sienna Reinders Reporter Alexandra Pfau Theme Music: Joe Bergsieker
Fitness mit M.A.R.K. — Dein Nackt Gut Aussehen Podcast übers Abnehmen, Muskelaufbau und Motivation
Schon ein halbes Kilo Flüssigkeitsverlust kostet Dich messbar Kraft, Ausdauer und Konzentration. Und die meisten Menschen merken es nicht mal.Du kommst vom Training, trinkst einen Liter Wasser – und eine Stunde später bist Du dreimal auf der Toilette gewesen, aber immer noch durstig. Das ist kein Zufall. Dein Körper scheidet das Wasser aus, das er eigentlich braucht. Und die Ursache ist ein einziger Mineralstoff, der in Deiner Flasche fehlt.Am Ende dieser Folge weißt Du, welches Getränk aus Deinem Kühlschrank laut Forschung besser hydratisiert als die meisten Sportgetränke. Warum letztere im wissenschaftlichen Ranking alle auf Wasser-Niveau landen. Und welcher einfache Kniff dazu führt, dass Dein Körper die Flüssigkeit wirklich aufnimmt.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.
Leigh Stallard is joined by Lara Manton and Robbie White for a packed episode recorded in the wake of Accountex 2026. Between them they cover eight stories spanning practice management, bookkeeping automation, MTD, AI strategy and the long-running question of what an accountant is actually for. Duane Jackson's Sodium has moved to general availability. It is API-first, built around a single client record and designed with AI integrated from the start rather than bolted on later. Leigh frames the real challenge not as product quality but as firm inertia: practice management is the Lego wall nobody wants to dismantle, and a golden brick is only useful if someone is prepared to pull the old ones out. Lara and Robbie both know from experience how painful that process is, and the conversation turns quickly to whether AI-assisted migration might eventually lower the barrier. Apron's William AI is now generally available, having launched in beta in March. Lara walks through what it actually does: connecting to client email inboxes, extracting and categorising documents, publishing to Xero or QuickBooks, and flagging anything it is not confident about. The auto-publish toggle defaults off and needs firm-specific guidance rules to reach its potential. The beta hit 50% autonomous publish rate; the GA pitch is 90% for firms that put the configuration work in. Robbie leads on the Xero and Claude integration, which went live globally on 12 May. Early practitioner testing found it read-only, limited to account-level data and prone to missing transactions. Leigh and Lara discuss what it means that the major general ledgers are simultaneously embedding AI inside their own products and surfacing their data inside the large language models. Intuit's intelligence layer across QuickBooks covers AI-powered chat, portfolio benchmarking and a capability that appears pointed directly at end clients. Lara raises the concern that clients with incomplete books could get confident-sounding answers to questions they should be asking their accountant instead. Lara covers the QuickBooks AI-powered MTD checker, which flags duplicates, missing transactions and non-trading income sources before submission. QuickBooks claims the highest cumulative MTD pilot sign-ups during HMRC's testing period. Robbie welcomes it as a live use case rather than a theoretical one. Robbie covers Combinely, the browser-based AI co-worker backed by YC and OpenAI. Early UK adopters include Burgess Hodgson, where it handled 2,600+ tasks across December and January with a reported 75% reduction in income and expenditure creation time. Leigh raises the structural tension: a tool that sits on the periphery of a workflow is easy to adopt and equally easy to quietly drop. Lara covers FreeAgent's integration with Equali, pulling e-commerce data from Shopify into FreeAgent for reconciliation and categorisation, and notes FreeAgent's incoming Apron partnership as part of a broader push beyond its freelancer roots. The episode closes on the Accountex panel from ICAEW, ACCA and IFAC. The fat middle concern runs through the final section: AI handling transactional work, hollowing out the junior pipeline and, with it, the intuition that comes from years of doing the basics. Robbie's view is that AI will eventually learn the human stuff too. The question is what accountants do with the time that creates. Chapter list 00:00 Introduction and Overview of Topics 04:00 The Launch of Sodium: A New Practice Management Tool 08:25 Apron's William AI: Enhancing Document Management 12:44 General Ledgers and AI Strategies 23:31 QuickBooks AI-Powered MTD Checker Flags Errors Before Submission, Not After 27:18 Combinely's AI Co-Worker Handles 2,600+ Tasks in a Month for Early UK Firm Adopters 30:45 FreeAgent's E-Commerce Expansion 36:09 The Future of Accountancy: AI and Brand Perception
Episode Highlights With KatieWhat humic and fulvic minerals actually are ... and why they're not electrolytesThe difference between fulvic (small, cellular) and humic (larger, gut-supportive)Why these minerals used to come from rich soil… but don't anymoreHow humic minerals bind toxins gently without stripping nutrientsHow fulvic minerals improve mineral absorption & mitochondrial signalingTheir role in gut health, microbiome balance, and gut lining repairHow they help move sodium, potassium, magnesium into the cellWhy they're crucial for detoxification in a modern environmentHow humic/fulvic increase cellular voltage and hydrationHow to take them: liquids, drops, powders & when they're most helpfulWhy these aren't “either/or” ... they are a both/and with electrolytesResources MentionedBEAM MineralsHiyaHiya created a super powered chewable vitamin for kids that packs twelve organic fruits and vegetables plus fifteen essential vitamins and minerals into every dose. Try it at hiyahealth.com/wellnessmama for 50% off your first order.BioptimizersI love and use so many products from them, but I especially love the magnesium and digestive enzymes. Visit bioptimizers.com/wellnessmama and use wellnessmama15 at checkout to get the best deal
I'm Diane, and I'm here with my daughter Alysha (aka Eash Da Beast), and in this episode we're sitting down just 8 days out from her bodybuilding show - peak week is officially in full swing! We're talking through what life really looks like right now in prep: the low energy days, carb thoughts taking over everything, shredded lettuce cravings, and the routines that come with getting stage-ready. We also break down what typically shifts this close to show day when it comes to food, cardio, water, and mindset, and why keeping things as consistent and simple as possible becomes the main focus. We also get real about the day-to-day experience of peak week - sleep, sodium, cravings, and trying not to overthink every little change in the mirror. And of course, we still end up talking about post-show food dreams… because that's basically part of prep at this point
Episode Highlights With KatieWhy potassium is the #1 most underconsumed mineral todayHow potassium runs the sodium–potassium pump that powers the entire bodyWhy potassium is the mineral of calm electricity and inside-cell stabilityHow potassium affects insulin sensitivity, blood sugar, and metabolismThe role of potassium in heart rhythm, muscle relaxation, and digestionWhy low potassium mimics anxiety and hormone imbalanceHow potassium balances sodium and helps magnesium work betterThe best food sources ... fruits, roots, coconut water, beans, greensWhy low-carb and RO water increase potassium needsPractical ways to add more potassium without supplementsWhy potassium is essential for cell voltage, hormone signaling, and nervous system safetyResources MentionedLMNT electrolyte drinksBONCHARGEI like so many of their products - from their red light products to their sauna blankets. Red light has been so helpful for me during my recovery from Hashimoto's. To find out more, go to boncharge.com/wellnessmama and use code wellnessmama for 20% off!LMNTI talk often about the health benefits of salt and electrolytes and I am a big fan of LMNT canned drinks and packets. Go to drinklmnt.com/wellnessmana for a special offer.
Send us Fan MailThis episode features Scott Hamilton, CEO of United Chemical, discussing the EPA's recent restrictions on sodium bromide, its implications for pool professionals, and the science behind bromate formation and safety. Gain insights into regulatory processes, chemical safety, and effective pool management strategies.keywordssodium bromide, EPA regulations, bromate, pool chemistry, pool safety, algae control, chemical risk assessment, United Chemical, Yellow Treat, bromine poolskey topicsEPA's restrictions on sodium bromideBromate formation and health risksScience and risk assessment of pool chemicalsguest nameScott HamiltonSound Bites"Don't let your mentor go, that's mentoreward.com.""Bromamines are effective and don't have a nasty smell.""Pool pros should voice their concerns to regulators."Chapters00:00Introduction to the EPA's Controversy on Sodium Bromide03:52The History and Impact of Bromate Regulations06:53Understanding Bromate Formation in Pools09:30The Chemistry of Bromine and Chlorine in Pools12:18The Misconceptions of Bromine Pools15:16Toxicology of Bromate and Cancer Risks18:12Bromate in Food Products and Regulatory Delays22:25Understanding EPA's Role and Challenges25:10The Impact of Lobbying on Chemical Regulations29:45Efficacy of Sodium Bromide in Algae Control30:50Trends in Mustard Algae Growth34:22Research Findings on Bromate Formation42:48Engaging with Regulatory Bodies45:40Legacy and Safety of Sodium BromideResourcesUnited ChemicalYellow TreatEPA Regulations on Bromide Products (2005)Bromate Risk Assessment Study AquaStar Pool ProductsThe Global Leader in Safety, Dependability, & Innovation in Pool Technology.BLUERAY XLThe real mineral purifier! Reduce your pool maintenance costs & efforts by 50%CPO Certification ClassesAttend your CPO class with Rudy Stankowitz!Jack's MagicIf you know Jack's you'd have no stains!Service Industry NewsDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThank you so much for listening! You can find us on social media:FacebookInstagramTik TokEmail us: talkingpools@gmail.com
Ultra-processed food makes up over half the calories Americans eat - and over 60% for kids. Here's what the research shows happens inside your body in the first 5 days after you quit. In this episode of Health Longevity Secrets, Dr. Robert Lufkin walks through the hour-by-hour timeline: the glucose spikes that disappear within 24 hours, the insulin resistance that drops 30%+ in 48 hours, the gut microbiome that reorganizes in 3 days, the blood pressure that falls 6-8 mmHg in a week, and the NIH metabolic ward data showing a 500+ calorie daily swing driven entirely by food processing - not willpower. CHAPTERS 00:00 - Introduction: Why Ultra-Processed Food Matters 00:47 - Part 1: What Happens in the First 24 Hours 01:30 - Sodium, Water Retention and the Real Reason You Lose 1-3 lbs 02:10 - Part 2: 48 Hours - Insulin Sensitivity Returns Within Days 02:45 - Gut Microbiome Shifts in 24 Hours (David et al., Nature 2014) 03:23 - Taste Receptors Recalibrate: Why Fruit Tastes Sweeter Again 03:55 - Part 3: 72 Hours - Blood Pressure Drops 6-8 mmHg 04:34 - Inflammation Falls 35-43% in One Week (CRP Data) 05:30 - Part 4: 5 Days - Kevin Hall's NIH Metabolic Ward Trial 06:58 - Part 5: The Framework - 120 Hours to Reset Your Biology KEY TAKEAWAYS Glucose stabilizes within 24 hours when fiber and food matrix are restored 3 low-carb meals can reduce post-meal insulin resistance by over 30% in a day Gut bacterial composition shifts within 24 hours of dietary change Sodium reduction lowers systolic BP 6-8 mmHg in 70-75% of people in one week CRP drops 35-43% in 7 days on a whole-food, vegetable-rich diet Kevin Hall's 2019 NIH RCT: ultra-processed diet drove 500+ extra calories/day with zero awareness STUDIES AND SOURCES Hall et al., Cell Metabolism 2019 - NIH metabolic ward UPF trial David et al., Nature 2014 - diet alters gut microbiome Shukla et al., 2019 - meal sequence and postprandial glucose American Journal of Medicine 2026 - UPF and 47% increased CV risk AHA Scientific Sessions 2023 - sodium and BP in one week Lin and Borer, PLOS ONE 2016 - ⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every Tuesday & Thursday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/
In this video, Dr. Ruscio discusses 8 benefits of taking butyrate, a fat molecule with gut and systemic healing properties. Butyrate is produced by gut bacteria, but it is often low in different chronic health conditions. Supplementation has been shown to improve a variety of gut conditions, including IBS, IBD, and SIBO, as well as chronic inflammation and brain health. Doctor Ruscio also discusses some simple dietary strategies to increase butyrate production naturally. ✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/
Episode Highlights With KatieWhy magnesium is the master mineral your body burns through fastestThe real reason magnesium powers 700+ reactions in the bodyHow magnesium activates ATP and mitochondrial energyWhy stress, pregnancy, and modern life create chronic depletionThe difference between forms like glycinate, citrate, malate, threonate, taurate, etc.Why I personally use Magnesium Breakthrough (7 forms)How topical magnesium oils, lotions, and baths work & when to use themSymptoms of magnesium deficiency (that don't look like deficiency!)How magnesium interacts with sodium, potassium, calcium, and hormonesHow magnesium supports sleep, digestion, blood sugar & nervous system calmWhy magnesium is a primary safety signal for the bodyResources MentionedMagnesium Breakthrough supplement (use code wellnessmama for 15% off)Magnesium lotionMagnesium oilHiyaHiya created a super powered chewable vitamin for kids that packs twelve organic fruits and vegetables plus fifteen essential vitamins and minerals into every dose. Try it at hiyahealth.com/wellnessmama for 50% off your first order.BioptimizersI love and use so many products from them, but I especially love the magnesium and digestive enzymes. Visit bioptimizers.com/wellnessmama and use wellnessmama15 at checkout to get the best deal
Recorded live at the 2026 Beijing Auto Show, Elliot Richards sits down with Dr. Zhu Lingbo "LB", CTO of CATL's International Business Unit, for a conversation about the battery technologies that are reshaping the automotive industry. From 3-minute charging and 1,500 km batteries to the reality of solid-state development, this episode delves into the breakthroughs, bottlenecks, and global power struggle defining the future of EVs. LB Zhu explains how CATL's latest Qilin and Shenxing battery platforms are pushing energy density, charging speed, and weight reduction further than ever before, and why the company believes lighter batteries may matter just as much as bigger ones. In this episode: CATL's 3 min 44 sec charging breakthrough 350 Wh/kg "Condensed State" batteries Why EV weight is becoming a major battleground The real timeline for solid-state batteries CATL's expansion into Germany and Europe The future of battery recycling and circular supply chains China vs Europe in the global battery race 0:00 CATL's Vision for the Future of EVs 2:18 Qilin vs Shenxing: CATL's New Battery Breakthroughs 5:41 3-Minute Charging: How Fast Can EVs Really Get? 8:02 Sodium-Ion Batteries & the Next Chemistry Shift 10:27 Why EV Weight Is the Industry's Next Big Battle 14:20 Why 500 Wh/kg Batteries Aren't Ready for Cars 16:15 The Truth About Solid-State Batteries 19:06 Europe's EV Slowdown & Global Electrification Trends 23:18 Inside CATL's Expansion Into Germany 27:25 Battery Recycling & the Circular Economy Future 31:48 What EVs Will Look Like in 2036 Why not come and join us at our next Everything Electric expo: www.everythingelectric.show Check out our sister channel: https://www.youtube.com/c/EverythingElectricShow Support our StopBurningStuff campaign: https://www.patreon.com/STOPBurningStuff Become an Everything Electric Patreon: https://www.patreon.com/fullychargedshow Become a YouTube member: use JOIN button above Buy the Fully Charged Guide to Electric Vehicles & Clean Energy : https://buff.ly/2GybGt0 Subscribe for episode alerts and the Everything Electric newsletter: https://fullycharged.show/zap-sign-up/ Visit: https://FullyCharged.Show Find us on X: https://x.com/Everyth1ngElec Follow us on Instagram: https://instagram.com/officialeverythingelectric To partner, exhibit or sponsor at our award-winning expos email: commercial@fullycharged.show EE WEST (Cheltenham) - 12th & 13th June 2026 EE GREATER LONDON (Twickenham) - 11th & 12th Sept 2026 EE SYDNEY - Sydney Olympic Park - 18th - 20th Sept 2026 #fullychargedshow #everythingelectricshow #homeenergy #cleanenergy #battery #electriccars #electric-vehicles-uk #CATL #EVBattery #ElectricVehicles #SolidStateBattery #FastCharging #EVTechnology #BatteryTechnology #ElectricCars #Shenxing #QilinBattery #EverythingElectric #EVNews #ChinaEV #BatteryInnovation #FutureOfTransport #Electrification #SodiumIon #BatteryRecycling #EnergyStorage #BeijingAutoShow
Episode 1: Obedience Experiments & the Current Hantavirus Scare Lead-In / Hook • Open with the fresh Hantavirus cruise ship story (May 2026 outbreak on MV Hondius: cluster of cases, deaths, WHO alerts, media panic, comparisons to past pandemics). • Ask: “Another virus scare hitting the headlines — rodent-borne hantavirus on a cruise ship, rapid media coverage, public anxiety spiking. Sound familiar?” • Thesis: “This is the perfect real-time example of how authority, conformity, and ‘trust the experts' tactics — proven in classic psychology experiments — are still being used today in public health narratives.” Section 1: The Classic Experiments (Quick Recap) • Milgram Obedience: 65% of ordinary people administered what they believed were lethal shocks because an authority figure told them to. • Stanford Prison Experiment: Normal students became abusive guards or passive prisoners in days due to assigned roles and power structures. • Asch Conformity: People denied obvious reality (line length) to match the group. • Core lesson: Authority + perceived expertise + group pressure easily override personal judgment and common sense. Section 2: How These Tactics Show Up Right Now (Hantavirus as Exhibit A) • Rapid “trust the experts/WHO” framing and fear-based coverage despite experts noting low general-public risk and rare human-to-human transmission (mainly Andes strain in this case). • Labeling of questions or skepticism as dangerous or conspiratorial (Asch conformity in action). • Positioning public health agencies and media as the sole authority figures (modern Milgram). • Role assignment: Compliant citizens vs. reckless skeptics (Stanford Prison dynamic). • Tie to broader pattern: Same playbook seen in vaccine campaigns, statin guidelines, and repeated “emergency” messaging. Section 3: The Real-World Cost (Your Trenches Perspective) • After nearly 40 years coaching and still training at 63: Clients who followed official narratives saw declining performance, metabolic issues, lost resilience. • Psychology working as designed: Creates compliance and dependency while independent thinking erodes. • Profit angle: Institutions and industries benefit from sustained fear and reliance. Section 4: Breaking Free — The Thinking Man's Approach • Recognize the tactics: Treat health messaging like any high-pressure sales pitch — question it. • Use your own data: Track personal metrics (energy, strength, how you feel) over blanket guidelines. • Build real resilience: Smart intensity training (Tabata intervals — 4 minutes of hard effort) that delivers measurable results without waiting for official approval. • Reclaim agency: Decisions based on your body and long-term outcomes, not external pressure. Closing / CTA • Once you see the pattern, you can't unsee it. • Grab the free Policy-Proof Your Health Checklist. • Question of the week: “Have you seen fear-based health messaging influencing your decisions lately?” • Empowering close: Listen to your body, think critically, and stay in control. Episode 2: Refuting Gatorade's “Hydrates Better Than Water” Claims Intro / Hook • Relatable question: “Have you ever reached for a Gatorade (even the new lower-sugar version) thinking it hydrates you better than plain water?” • Thesis: “The electrolyte science has a kernel of truth in specific situations, but the broad marketing claim is wildly overstated for most people. There's a simpler, cheaper, cleaner option that works just as well — or better.” Section 1: What Gatorade Actually Claims • Sodium helps retain fluid, maintain blood volume, reduce urine output. • Carbs + sodium boost absorption (via SGLT1 transporters) in full-sugar versions. • They apply the “proven electrolyte blend” messaging broadly, including to everyday use and the lower-sugar version. • Recent pivot: Pushing hydration for regular people, not just athletes. Section 2: Kernel of Truth (Stay Balanced) • In prolonged intense exercise (>60–90 min), heavy sweating, heat: Electrolytes (especially sodium) do help replace losses and improve retention. • “Salty sweaters” and endurance athletes see real benefit. • Give credit where it's due — no denying the narrow use case. Section 3: Context Is Everything — The Refutation • ACSM guidance: For exercise under ~1 hour or moderate intensity, little to no difference vs. plain water. • Normal diet already supplies most daily electrolytes. • Much of the perceived superiority is palatability (people drink more flavored liquid). When volume is equal, the gap shrinks dramatically. • Lower-sugar version loses most of the carb-absorption advantage. Section 4: The Better Alternative — DIY Salt Water • Simple recipe: 16–20 oz water + 1/8–1/4 tsp high-quality sea salt (~300–500 mg sodium) + squeeze of lemon/lime. • Optional: Tiny bit of honey for longer sessions. • Why it wins: Full control over sodium, zero added sugar/additives, much cheaper, cleaner. • Evidence: Sodium-enhanced fluids improve retention in relevant scenarios (Beverage Hydration Index research). • Advantages: Avoid excess sugar, customize to your needs, no marketing hype. Section 5: Critique of the Research • Often-cited studies (e.g., small 2008 kayaker trial) have limitations: tiny samples, specific conditions, industry ties (GSSI). • Independent sources (Harvard Health, ACSM): Water + balanced diet is enough for the vast majority of people. Conclusion & Takeaways • Bottom line: Pinch of salt in water beats Gatorade for everyday or moderate activity. Save commercial drinks for true long, brutal endurance efforts in extreme conditions. • Action step: Try the DIY version this week and compare how you feel. • Listener question: “What's your go-to hydration strategy?” • Empowering note: Hydration doesn't need to be expensive or complicated — listen to your body and use common sense. These talking points keep both episodes concise, conversational, and true to your style. The obedience episode leads strongly with the timely Hantavirus example, then flows naturally into practical health ownership (including hydration as a real-world application).
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Hydration is one of the most overlooked levers in endurance performance — and one of the most punishing when you get it wrong. In this episode, Zoë and TJ unpack why dehydration is so much more than feeling thirsty, walking through the cascading downstream effects on your gut, your blood, your muscles, and ultimately your race result. They cover gut osmolality and why a too-concentrated drink mix actually pulls water the wrong way, the link between plasma volume drop and cardiac drift, and why dead legs late in an ultra often trace back to a sodium problem rather than a fitness one.The conversation then turns to the practical side: how to DIY your sweat rate test at home, why your sweat sodium concentration is the number that changes everything, and which lab tests Zoë and dietician Kylee Van Horn actually recommend after testing six different options. They also break down why generic 300–800 mg per hour sodium guidance fails most athletes, with real roster examples ranging from 200 mg to over 2,300 mg per hour.Before the hydration deep-dive, Zoë and TJ tackle a thoughtful listener question about the asides they sometimes make regarding endurance training and sexual health. They walk through the RED-S framework, what suppressed libido and menstrual dysfunction actually signal in athletes of all genders, and why these conversations belong in the coaching toolkit rather than as punchlines. Coach Kylee Van Horn at Fly Nutrition is mentioned as a go-to sports dietician for clinical questions.If you've ever had a mystery DNF, persistent GI distress, or fallen apart late in a race for reasons you couldn't pin down, this is the episode to listen to twice.Questions, topics, hot or nots: microcosmcoaching@gmail.com Learn more: microcosm-coaching.com
You asked we answered! - What is the best way to rebound post comp?- Is there a golden ratio for potassium and sodium to produce a dry, full, hard look on show day?- When should you remove thyroid post comp? Join us for those answers, and some laughs. Two Truths One Lie for Coach George1. After using GH one of my feet has grown longer than the other2. I once played semi professional football in the UK3. In the past I considered myself a drug addict, but it has been X years of having never used it since deciding I was done with it Fan of the show?If you find value in the Flex Success Podcast, we'd love it if you could show your support by leaving a review on iTunes. This will help expose the show to a bigger audience so we can help more people be less shit. To find out more about Flex Success, head to:https://www.flexsuccess.com.au/ https://www.instagram.com/flex_success/ To find out more about Dean, George and Ryan head to:https://www.instagram.com/flexcoach_dean/ https://www.instagram.com/flexcoach_george/ https://www.instagram.com/flexcoach_ryan/ Disclaimers: Flex Success, and the associated coaches, are not doctors or medical professionals. Always consult a physician before starting any exercise program. Use of this information is strictly at your own risk. Flex Success will not assume any liability for direct or indirect losses or damages that may result from the use of the information contained in this video including but not limited to economic loss, injury, illness or death.
For decades, we've been told to cut back on sodium to protect our hearts. But what if that advice is not just wrong, but actively harming your health and performance? In this episode, I expose the truth about sodium, blood pressure, and cardiovascular risk. We'll dive deep into the outdated science that created the sodium myth, revealing why blanket recommendations are dangerous for most healthy individuals. Discover how restricting sodium can worsen insulin resistance, increase heart rate, and even sabotage your performance. Grab your set for the upcoming workshopTopics discussed: - Sodium as an electrolyte- Salt-sensitive hypertension- Dangers of sodium restriction- Salt-blood pressure hypothesis- Difference between correlation and causation- New data on sodium and blood pressure- Real causes of sodium-sensitive hypertension- Insulin resistance and elevated aldosterone levels- The importance of the sodium-potassium balance- How to determine appropriate sodium intake---------- My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization www.metabolismschool.com---------- [Free] Metabolism School 101: The Video Serieshttp://www.metabolismschool.com/metabolism-101----------Subscribe to My Youtube Channel: https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1----------Grab a Copy of My New Book - Metabolism Made Simple---------- Stay Connected: Instagram: @sammillerscienceYoutube: SamMillerScience Facebook: The Nutrition Coaching Collaborative CommunityTikTok: @sammillerscience----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at operations@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."
Episode Highlights With KatieWhy sodium is the most misunderstood mineralHow sodium runs your body's electrical system, nerves, and musclesThe surprising connection between sodium and safety signalsWhy many health-conscious women are quietly under-sodium-edSymptoms of low sodium that look like stress or anxietyHow sodium interacts with potassium and magnesiumWhy sodium needs to come from mineral-rich salts, not processed foodsMicroplastics in sea salt and better alternativesHow to increase sodium safely in a real-food lifestylePractical ways to hydrate with electrolytes without overdoing waterWhy sodium is essential for sauna, exercise, pregnancy, and stress recoveryResources MentionedHimalayan salt tabletsLMNT electrolyte drinksBONCHARGEI like so many of their products - from their red light products to their sauna blankets. Red light has been so helpful for me during my recovery from Hashimoto's. To find out more, go to boncharge.com/wellnessmama and use code wellnessmama for 20% off!LMNTI talk often about the health benefits of salt and electrolytes and I am a big fan of LMNT canned drinks and packets. Go to drinklmnt.com/wellnessmana for a special offer.
If you have ever wondered why you are holding water despite doing everything right, this episode is for you. I dive into the complex physiological mechanisms behind water retention, moving beyond the simple vanity aspect to explore its real impact on health. By understanding these root causes, you can stop second-guessing your plan, avoid the "screw it" effect, and manage those normal fluctuations with an objective, informed perspective. Topics discussed: - The health implications of water retention- The three main hormones controlling water balance- The role of stress and high cortisol - The Minnesota Starvation Experiment- The impact of poor sleep and circadian rhythm- Sodium and potassium imbalances- The relationship between carbohydrate intake, glycogen storage, and water weight---------- My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization www.metabolismschool.com---------- [Free] Metabolism School 101: The Video Serieshttp://www.metabolismschool.com/metabolism-101----------Subscribe to My Youtube Channel: https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1----------Grab a Copy of My New Book - Metabolism Made Simple---------- Stay Connected: Instagram: @sammillerscienceYoutube: SamMillerScience Facebook: The Nutrition Coaching Collaborative CommunityTikTok: @sammillerscience----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at operations@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."
Guest: Cynthia Thurlow, NP — Author of The Menopause Gut | 2x TEDx Speaker In this episode:How a Morocco trip landed Cynthia in the hospital for 13 days — and what God showed her thereWhy your gut is the key longevity organ you've never heard ofThe gut-brain, gut-bone, and gut-ovarian axes — how it's all connectedWhy "I go to the bathroom every day" doesn't mean your gut is healthyWhy digestion starts in the brain — not your stomachHow stress spikes your blood sugar more than food doesSkin rashes, brain fog, and psoriasis as gut signals — not separate problemsShort chain fatty acids, sodium butyrate, and rebuilding the microbiomeWhy postmenopausal women need to stop thinking about their hormones in silosCynthia's non-negotiables: sleep, boundaries, fiber, HRT, and no alcoholResources: Free Midlife Gut Guide → http://themenopausegut.com/midlife-gut-guide?am_id=tabatha7584 The Menopause Gut Book → https://themenopausegut.com/?am_id=tabatha3589 All-In-One Microbiome Lift → shop.fasttofaith.com/product/gut-lift/ Use code PODCAST for 20% off"I will restore your health and heal your wounds, declares the Lord." — Jeremiah 30:1700:00 — So many women have lost hope — give them some right now 00:58 — Welcome back: spring break, nature, and God's goodness 02:38 — Introducing Cynthia Thurlow: author, 2x TEDx speaker 04:11 — Pain to purpose: the theme of Fast to Faith guests 05:35 — Why women still don't know this information 06:36 — Cynthia's personal journey: how it all started 07:34 — Morocco, food poisoning, and 13 days in the hospital 12:54 — God is doing good works — are you getting on board? 15:35 — Giving women permission to advocate for themselves 15:45 — Omega Lift: why omega-3s matter more than ever 18:30 — How Cynthia healed: 9 months carnivore, 18 months to vegetables 22:04 — Why you can't eat fiber when your microbiome is decimated 23:19 — Carnivore as therapeutic — not forever 24:00 — Digestion is a north-to-south process — it starts in the brain 29:19 — Sodium butyrate and rebuilding the microbiome 30:51 — Gut health affects serotonin, GABA, and dopamine 31:52 — Your gut health determines your longevity 35:39 — Genesis, the microbiome, and how God designed us 36:39 — Skin rashes and psoriasis as gut signals 38:34 — Healthy Her: catching the signals before they become crises 39:35 — Healing takes years — not weeks 40:21 — Blood sugar, cortisol, and the CGM lesson 42:05 — It took time to learn these boundaries 42:19 — Cynthia's non-negotiables: sleep, stress, fiber, HRT, no alcohol 47:41 Ready to stop trying harder and start healing smarter? Start with the $5 Faith Reset Challenge — your first step to regulating your nervous system, stabilizing your metabolism, and reconnecting with your identity in Christ through simple, faith-centered rhythms. This is where most women begin.
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Dietary Sodium Intake and Risk of Incident Heart Failure in the Southern Community Cohort Study.
Electrolytes don't start and end with tossing some sodium into your water and hoping for the best. Brooke, Sabrina, and Lauren talk about the sodium-potassium balance that helps hydration do its job. They break down why sodium gets all the attention, why potassium is usually the missing piece, and how this balance affects energy, recovery, cramping, performance, and how you feel day to day. They also get into why so many people are under-eating potassium, why more water is not always the answer, how athletes' needs can differ from the general population, and what to watch for if your hydration strategy is falling flat. From salty sweaters to supplement marketing to practical food swaps, this one covers the stuff people usually miss. Black Iron Nutrition Book a Free Discovery Call Free Macro Calculator Free Downloads Black Iron Blog
The House Judiciary Committee just dropped a 47-page report calling the National Residency Match Program a hiring monopoly that harms patients, doctors, and the public — and the surgical community is talking. In this episode, Dr. Patrick Georgoff is joined by BTK surgical education fellows Dr. Emma Burke and Dr. Agnes Prem Kumar, along with special guest Dr. Brian Carmody (aka the Sheriff of Sodium), a pediatric nephrologist and one of the sharpest analysts of medical education policy working today. Together, they break down the report's central claims: that the NRMP exercises monopolistic control over residency hiring, suppresses resident wages, and strips trainees of bargaining power — and they separate what the report gets right from where its rhetoric badly outruns its evidence. From the history of Section 207 and the antitrust lawsuit that nearly brought down academic medicine, to the real economics of GME funding, resident unionization, and what a match-free world would actually look like — this is the context you need to understand one of the most consequential debates in graduate medical education in years. Don't miss Dr. Carmody's six-part YouTube series on the match, linked in the show notes.Congressional Report: https://judiciary.house.gov/media/press-releases/new-report-exposes-how-medical-residency-hiring-monopoly-harms-patients-andThe Match 6-Part Video Series: https://www.youtube.com/playlist?list=PLc36yFQWkuG1sXk62A3zeRWB8aoK5SISPThe Sodium Sheriff Blog: https://thesheriffofsodium.com/***Fellowship Application Link: https://forms.gle/QSUrR2GWHDZ1MmWC6Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium:General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewOral Board Simulator: https://app.behindtheknife.org/oral-board-simulatorTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode1121 In this episode, I’ll discuss using sodium bicarbonate instead of hypertonic saline to treat severe hyponatremia.
What if your gut has been signaling a problem for your brain for years? That is exactly what the latest science on the gut microbiome and Parkinson's disease is revealing, and it begins with something as overlooked as constipation. If you have ever dismissed a sluggish digestive system as no big deal, this conversation may be the most important one you hear all year.Salad With a Side of Fries host Jenn Trepeck welcomes Martha Carlin, microbiome researcher, founder of The BioCollective and a woman who traded a corporate career for a microscope after her husband was diagnosed with Parkinson's at 44. What she has uncovered about gut bacteria, endotoxin load, the glycocalyx, and neurological decline is both startling and deeply actionable. This is not fear, it is fuel for better choices.What You Will Learn in This Episode:✅ Why chronic constipation is far more than a digestive inconvenience and how waste sitting in the colon produces an endotoxin load now linked to Parkinson's, depression, autism, and diabetes.✅ What the glycocalyx is, why it matters for everything from gut health to cardiovascular function, and how damage to this critical structure can spread throughout the entire body over time.✅ How H. pylori consumes dopamine in the gut, why that interaction may explain why Parkinson's disease medications lose effectiveness, and what the research from Harvard reveals about this connection.✅ The surprising ways that endurance athletics, over-cleaning with quaternary ammonium compounds, and glyphosate-exposed foods all quietly assault the gut microbiome and compound your risk over time.The Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.TIMESTAMPS:00:00 Martha Carlin's powerful warning: constipation creates a toxic burden linked to Parkinson's disease and neurological decline05:18 How Martha's husband's Parkinson's disease diagnosis launched her career in gut microbiome research07:08 How specific gut bacteria profiles reveal two distinct types of Parkinson's disease10:02 The concrete stool discovery: how electrolyte imbalance, sodium, and potassium disrupt nerve signaling and drive constipation12:24 Connection between chronic constipation and toxin reabsorption to autism, depression, diabetes, and neurological disease13:17 Glycocalyx: the overlooked protective barrier linking gut health to brain and cardiovascular function21:25 Quaternary ammonium compounds in cleaning products have more than doubled since COVID and are now linked to immune system disruption and Parkinson's disease24:06 Why Parkinson's disease is multifactorial: the glycocalyx as a self-assembled structure that becomes unstable over time29:18 A morning ritual backed by 1912 research: warm water with kosher salt and lemon to support gut health and daily elimination, and the definition of regular elimination33:19 Prebiotics, probiotics, and postbiotics work together across the GI tract, with butyrate as a critical fuel for the glycocalyx37:11 How Sugar Shift probiotics and apple cider vinegar with the mother can help break down glyphosate and support gut microbiome health41:47 Martha's closing message of hope: diet, exercise, gut health, and daily habits can shift the trajectory of Parkinson's diseaseKEY TAKEAWAYS:
Albumin is one of those topics where everyone has an opinion, but very few people actually look at the cost-benefit data. In this lecture, I'm breaking down why the 5% albumin you're hanging might be a waste of money, and where the 25% concentration actually moves the needle in septic shock and cardiac surgery.In this episode, we cover: The "Cool" Science: Where does this stuff come from? (Cold Cohn Fractionation). The Price Tag: Why your hospital administrator cringes when you order it.Sepsis & Septic Shock: What the SAFE and ALBIOS trials actually showed vs. the "statistical gymnastics" used to find a benefit.Cardiac Surgery: Does it help the kidneys or hurt them? (Comparing ALBICS-AKI and HAS-FLAIR II). The Lasix Combo: Is there a real mortality benefit to the albumin-lasix "concoction"?Citations: All data points have PubMed IDs listed in the slides. Please read these for yourself. Disclaimer: This is for educational purposes only and is not medical advice. I'm an ICU physician, but I'm not your physician.Timestamps:0:00 Intro & Disclaimers 1:45 How Albumin is made (and why the glass bottles?) 4:30 Electrolyte breakdown: Sodium and Chloride concerns 6:00 The actual cost vs. Saline/LR 9:15 Why our patients' albumin levels drop in the first place 12:30 Sepsis survival: The statistical gymnastics 16:00 Septic Shock & 20% Albumin 19:00 Early Resuscitation: Should you wait 6 hours?22:30 Cardiac Surgery: The AKI controversy 26:15 Albumin & Lasix: Does it actually work? 29:00 Final Verdict: Is 5% Albumin dead?The Vasopressor & Inotrope HandbookAmazon: https://amzn.to/47qJZe1 (Affiliate Link)My Store: https://eddyjoemd.myshopify.com/products/the-vasopressor-inotrope-handbook (Use "podcast" to save 10%)
In this episode, I have the privilege of interviewing Cody McBroom, founder of Tailored Coaching Method. We dive into a practical conversation on fat loss, performance nutrition, and the key mistakes keeping most people from getting results.Connect with Cody: IG | YouTubeTopics00:00 – Intro01:54 – Cody's Background 05:50 – Early Coaching Lessons & Principles 15:29 – Performance vs Aesthetics: Body Fat, Health, and Long-Term Mortality 18:13 – Sodium, Food Choices, and Scale Spikes 19:51 – Nutrition for Hybrid Athletes vs Gen Pop 20:45 – Carbs Are the Performance Lever 21:27 – How Much Protein You Actually Need 23:46 – How to Fuel Training (Pre/Intra) 28:14 – Why You're Not Losing Weight32:07 – Macro Setup That Actually Works 33:07 – The Problem With Low Carb Diets 38:53 – All You Need Are 7g of Fat Per Day 48:07 – Food Tracking: The Skill Most People Avoid —New Running Program: TTM Run AdvancedNew Selection Prep Program: Ruck | Run | Lift New Hybrid Program: Jacked Gazelle 3.0Ebook: SOF Selection Recovery & Nutrition Guide—TrainHeroic Team Subscription: T-850 Rebuilt—PDF programs2 & 5 Mile Run Program - run improvement program w/ strength workKickstart- beginner/garage gym friendlyTime Crunch- Workouts for those short on timeHypertrophy- intermediate/advancedJacked Gazelle- Hybrid athleteJacked Gazelle 2.0 - Hybrid athleteSFAS Prep- Special forces train-upRuck | Run | Lift - Selection Prep—Rice ‘N Grinds (Pride Foods) – 10% off w/ code TTMSpoken Supplements: Code terminator_training—Let's connect:Newsletter Sign UpIG: terminator_trainingYoutube: Terminator Training Methodwebsite: terminatortraining.comSubstack
* Jeffs Bagel Run garlic bread bagel blowing up in Bagel Madness * Huge variety of bagels and spreads, family friendly go to spot * Salt bagel with buffalo cream cheese as a standout combo * Bagel boxes at work instantly boost your social ranking * Expansion across Florida with app signup free bagel promo * BDM Appreciation Week tie in with free bagel giveaway * Debate on podcast intros, comfort of routine vs jumping in * Older episodes had heavier reverb and different audio feel * Payphone microphone prop added purely for comedy * BDM Appreciation Party April 11 with family duo theme * Jeff Howell and Casey Howell live music set * Juggling Jacks mother daughter act with poodles and props * Outdoor setup with pinball machines and fundraiser tables * Event is kid friendly but still classic chaotic T and D energy * Tiger Woods crash body cam footage and police interaction * Claim he was talking to the president during arrest * Debate if powerful people still avoid real consequences * Past stories of getting let off vs modern strict procedures * Body cams and social media killing police discretion * Sobriety tests used to build cases not prove innocence * HGN eye test explained as key DUI indicator * DUI outcomes depend heavily on money and legal help * Mo Dewitt sponsorship, VIP perks, and Mini Masters plug * Danger Brains branding, why visuals matter for small business * Bad logos and clip art instantly hurt customer trust * Turnstile as one of the biggest modern hardcore bands * Songs Blackout and Holiday pushing crossover success * Ex guitarist Brady Hebert arrested after violent incident * Drove car into singers father outside family home * Pattern of instability, drugs, and burning bridges * Discussion on how you would dodge an oncoming car * Wild stunt filming stories with near misses and bad decisions * E network dark side docs and Price Is Right allegations * Models pressured on weight, looks, and cosmetic changes * Debate on judging old behavior by modern standards * Bob Barker lawsuits and behind the scenes reputation * Docs can reshape public figures through editing choices * Ellen and Steve Jobs comparisons on workplace behavior * Tyra Banks and reality show treatment parallels * Supermodel nostalgia and cosmetic procedure risks * Artemis mission toilet malfunction and space skepticism * Automation vs manual control in spacecraft debate * Tesla self driving inconsistency discussion * Betting markets as crowd sourced prediction tools * Hot dogs taste better based on context and hunger * Costco and Primrose Lanes as elite hot dog experiences * Sodium and caffeine combo creating fake energy boost * Eating too many hot dogs leading to health scare moment * Preference for thinner dogs and chili slaw mustard combos * Varsity Atlanta and classic regional hot dog nostalgia * Adult Beanie Weenie upgrade and home cooking talk * Living with vegetarians makes solo cooking harder * Optometrist distraction story and outdated eye exams * Volunteers packing merch rewarded with food * Toy trends like Nitos and waiting out hype cycles * Paper towel wiping habit and plumbing consequences * Toilet paper folding vs crumpling debate * Elevator floor numbering confusion and 13th floor jokes * Black Hammock comedy show and Talks with Ross plug * Final push for BDM Appreciation Party attendance ### Social Media [https://tomanddan.com](https://tomanddan.com) [https://twitter.com/tomanddanlive](https://twitter.com/tomanddanlive) [https://facebook.com/amediocretime](https://facebook.com/amediocretime) [https://instagram.com/tomanddanlive](https://instagram.com/tomanddanlive) Where to Find the Show Apple Podcasts: [https://podcasts.apple.com/us/podcast/a-mediocre-time/id334142682](https://podcasts.apple.com/us/podcast/a-mediocre-time/id334142682) Google Podcasts: [https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkLnBvZGJlYW4uY29tL2FtZWRpb2NyZXRpbWUvcG9kY2FzdC54bWw](https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkLnBvZGJlYW4uY29tL2FtZWRpb2NyZXRpbWUvcG9kY2FzdC54bWw) Tom & Dan on Real Radio 104.1 Apple Podcasts: [https://podcasts.apple.com/us/podcast/a-corporate-time/id975258990](https://podcasts.apple.com/us/podcast/a-corporate-time/id975258990) Google Podcasts: [https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkLnBvZGJlYW4uY29tL2Fjb3Jwb3JhdGV0aW1lL3BvZGNhc3QueG1s](https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkLnBvZGJlYW4uY29tL2Fjb3Jwb3JhdGV0aW1lL3BvZGNhc3QueG1s) Exclusive Content [https://tomanddan.com/registration](https://tomanddan.com/registration) Merch [https://tomanddan.myshopify.com/](https://tomanddan.myshopify.com/)
Over 120 million Americans have high blood pressure! Simply reducing sodium won't always correct the electrolyte imbalance that could be keeping your blood pressure high. Uncover how to reduce blood pressure naturally by addressing the real hypertension causes no one talks about. 0:00 Introduction: Essential hypertension causes1:19 Sodium vs. potassium2:06 The sodium-potassium ratio explained3:48 Potassium for blood pressure6:06 Diuretics and electrolyte imbalance7:23 Potassium supplements9:44 Potassium and magnesium
In the Electrek Podcast, we discuss the most popular news in the world of sustainable transport and energy. In this week's episode, we discuss Tesla coming with minivan but cooler?, used EV sales rising, sodium batteries are coming, and more. The show is live every Friday at 4 p.m. ET on Electrek's YouTube channel. As a reminder, we'll have an accompanying post, like this one, on the site with an embedded link to the live stream. Head to the YouTube channel to get your questions and comments in. After the show ends at around 5 p.m. ET, the video will be archived on YouTube and the audio on all your favorite podcast apps: Apple Podcasts Spotify Overcast Pocket Casts Castro RSS We now have a Patreon if you want to help us avoid more ads and invest more in our content. We have some awesome gifts for our Patreons and more coming. Here are a few of the articles that we will discuss during the podcast: Tesla is coming out with ‘something cooler than a minivan', says Elon Musk Tesla (TSLA) publishes Q1 2026 delivery consensus: 365,645 vehicles expected Tesla Semi has a million-mile battery, claims Tesla New EV sales drop 28% in Q1 2026, but used EVs surge 12% to near-record levels Sodium-ion EV battery breakthrough delivers 11-min charging and 450 km range Slush pits and snowball fights: Slate's upcoming pickup endures winter testing [Video] Volkswagen Group's joint venture with Rivian hits latest milestone, unlocking another $1B for the EV automaker Honda pulls the plug on its PlayStation EV on wheels with Sony Here's the live stream for today's episode starting at 4:00 p.m. ET (or the video after 5 p.m. ET: https://www.youtube.com/live/mLpZ43Z-w-0
Can you help me make more podcasts? Consider supporting me on Patreon as the service is 100% funded by you: https://EVne.ws/patreon You can read all the latest news on the blog here: https://EVne.ws/blog Subscribe for free and listen to the podcast on audio platforms:➤ Apple: https://EVne.ws/apple➤ YouTube Music: https://EVne.ws/youtubemusic➤ Spotify: https://EVne.ws/spotify➤ TuneIn: https://EVne.ws/tunein➤ iHeart: https://EVne.ws/iheart RISING PETROL PRICES BOOST ULTRA-FAST CHARGING CASE https://evne.ws/3PHuskW BYD ADDS FREE FLASH CHARGING TO SONG ULTRA EV https://evne.ws/4lRzsj8 XIAOMI DEFIES CHINA EV MARGIN SQUEEZE https://evne.ws/40TQCms BAIC SHOWS 450 KM SODIUM-ION BATTERY https://evne.ws/4rP7dmn CHERY SETS OUT RHINO BATTERY RANGE https://evne.ws/4uRtoLm FREELANDER RETURNS ON MARCH 31 https://evne.ws/47WS0sn XPENG BRINGS TURING CHIP TO MONA M03 https://evne.ws/3PxewSi XPENG MONA D02 SUV BREAKS COVER https://evne.ws/4syN9pG NIO ES9 SPY SHOTS REVEAL FLAGSHIP SUV https://evne.ws/4sxnoWz