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Episode 202: BPA OverviewWritten by Cameron Carlisle, MSIV, Ross University School of Medicine. Comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice._____________________Arr: Welcome to another episode of Rio Bravo qWeek. My name is Hector Arreaza, I'm an associate program director and faculty in the Rio Bravo Family Medicine Residency Program. Today my co-host is Cameron Carlisle, who is a 4th-year medical student finishing his last rotation of med school. Welcome, Cameron, please introduce yourself.Arreaza: What are we talking about today, Cameron?Cam: Dr. Arreaza, did you know you're probably carrying around a chemical in your body that mimics estrogen? In fact, a 2004 CDC study found over 92% of Americans had detectable levels of Bisphenol A (BPA) in their urine. Today's topic is BPA.BPA is everywhere: receipts, water bottles, canned foods, baby bottles, and even our dental fillings. It's one of the most ubiquitous endocrine-disrupting chemicals (EDCs), which interferes with the body's hormone systems. That's why today's episode is about making the invisible visible. Our goals for today's podcast:Break down what BPA isShow how it affects the human bodyExplain how you and your patients can limit exposureEmpower both clinicians and the public with real, practical informationArreaza: Thanks for clarifying BPA today. It seems like we always have to learn about a new carcinogen or toxic substance that we are exposed to. I remember when I was a child, Yellow #5 became very concerning for the general public but it is still being used in our foods. So, it's good you are talking about this. What Is BPA?Cam: Bisphenol A (BPA) is an industrial chemical used since the 1950s, primarily in polycarbonate plastics and epoxy resins. It makes plastic clear, and is often found in:Water bottlesCanned food liningsBaby bottles (pre-2012)Takeout containersCash register receiptsDental sealantsArreaza: So, I've seen the “BPA-free” labels many times, and today I'm glad you are going to shed some light about it.Cam: What's alarming is that BPA leaches out of these products, especially when exposed to heat, acidity, or repeated use. A Harvard study found that people who drank from plastic bottles for just one week had a 69% increase in urinary BPA levels (Carwile & Michels, 2009).Arreaza: That's a lot of people 69%. Section 3: What happens when BPA gets into our body? How BPA Works in the BodyCam: BPA is classified as an endocrine disruptor, meaning it can bind to estrogen receptors and mimic or block natural hormone functions.It affects:Reproductive systems (both male and female)NeurodevelopmentThyroid signalingPancreatic β-cell functionMetabolism and fat storageEven low-dose exposure can disrupt cellular function. BPA acts as a xenoestrogen (foreign estrogen) and has been shown to alter DNA methylation, leading to epigenetic changes that persist across generations (Manikkam et al., 2013).Arreaza: So, BPA can cause epigenetic changes that can be inherited. BPA can persist for generations in your offspring.BPA's Health Impacts – What the Research SaysHere's where it gets serious. Let's go system-by-system:1. Reproductive HealthFemales: Linked to PCOS, infertility, and early puberty (Peretz et al., 2014).Males: Reduced sperm count and motility; altered testosterone levels.2. Pregnancy and Birth OutcomesIncreased risk of preterm birth, gestational diabetes, and low birth weight (Snijder et al., 2013).Studies show BPA crosses the placenta, directly affecting the fetus.3. Neurological DevelopmentAssociated with ADHD, anxiety, and impaired executive function in children exposed in utero (Mustieles et al., 2015).4. Metabolism and DiabetesBPA exposure is linked to insulin resistance, obesity, and type 2 diabetes, even at low doses (Lang et al., 2008).5. CancerAnimal and human data link BPA to increased risk of breast and prostate cancer via estrogenic mechanisms.6. MortalityA 2020 JAMA study found individuals with higher BPA levels had a 49% increased risk of all-cause mortality compared to those with lower levels (Gao et al., 2020).Arreaza: You are scaring me. I wonder what my BPA level is in my blood. Actually, BPA can be detected in urine. This is the most common approach for population-level biomonitoring, because BPA and its metabolites are mostly excreted in urine. Studies have found that BPA is present in most people, even up to 85–99% in large cohorts. Cam: That's literally everyone. Sources of BPA ExposureLet's talk about things we use every day:Thermal receipts (like from Target or Starbucks): BPA can transfer onto your skin and be absorbed, especially if your hands are wet or lotioned.Canned soups: One study showed that eating canned soup daily for five days led to a 1000% increased urinary BPA levels (Carwile et al., 2011).Plastic water bottles left in the car on hot days or plastic food trays for microwaving = chemical leaching.Baby bottles and pacifiers (pre-2012): primary concern for newborns.Arreaza: So, Cameron, you were exposed to BPA as a baby.Cam: Here's the jaw-dropper: We ingest up to 5 grams of plastic per week, roughly the weight of a credit card (WWF, 2019; University of Newcastle). This includes microplastics like BPA, which enter through food, water, and air.Arreaza: So, it translates into 40 lbs of plastic in a lifetime, by age 70. What can we do as family physicians?Family Medicine and Preventive CareAs family physicians, we are at the frontlines of prevention. Our role includes:Anticipatory guidance: during prenatal visits, well-child visits, and chronic disease managementScreening opportunities: ask about storage habits, microwave use, and receipt handlingEnvironmental health counseling: AAFP recommends addressing endocrine disrupting chemicals (EDCs) when relevant to a patient's concerns.It's not just about treating diabetes or obesity. It's about recognizing that environmental exposure may be a root cause.Arreaza: Prevention is my favorite topic!Cam: One helpful clinical practice:Arreaza: What else can we do to reduce BPA exposure?Practical Steps to Reduce BPAHere's what patients and doctors alike can do today:Switch to BPA-free products, but be careful, as replacements like BPS or BPF may also be harmful (Rochester & Bolden, 2015).Avoid microwaving or dishwashing plastic containers.Use digital receipts.Filter tap water using carbon filters, which can reduce microparticle ingestion.Choose fresh produce over canned goods when possible.Also, wash your hands after handling receipts, especially before eating or touching your face.Arreaza: What is our government doing to protect us?Public Health and Policy UpdatesRegulations are slowly catching up:The FDA banned BPA in baby bottles and sippy cups in 2012.The European Union has stricter limits, and France banned BPA in all food packaging in 2015.California's Proposition 65 requires BPA warning labels.Arreaza: Proposition 65, passed by direct voter initiative in 1986, “WARNING: This product contains chemicals known to the State of California to cause cancer and birth defects or other reproductive harm.”Arreaza: The FDA is planning to phase out petroleum-based food dyes (certified color additives) from the American food supply – marking a significant milestone in the efforts to protect the public. Cam: Many products still contain BPA analogs (BPS, BPF), which are not yet well-regulated.This is where clinician advocacy matters, where we can guide public opinion and support legislative change.Arreaza: So, millions of pounds of toxic substances are produced by many industries in the US. As physicians, we have to stay informed and update our patients.Cameron: How can we wrap up this episode?Conclusion and TakeawaysBPA is a hormone disruptor hiding in plain sight.People are exposed to BPA every day, but small lifestyle changes can dramatically reduce it.Family medicine has a role in education, prevention, and advocacy.Let's all be part of the solution for our health and future generations. Stanley (tumblers) are not sponsoring this episode, and we did not receive any money from them. Arreaza: That's it for today's episode of Rio Bravo qWeek. If you enjoyed this episode, share it with a colleague or medical student who may need to know about BPA. I'm Dr. Arreaza, signing off.Cameron: Hopefully, in the future I will talk to you about more endocrine disrupting chemicals. Thanks for listening._____________________Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Carwile, J. L., & Michels, K. B. (2009). Urinary bisphenol A and obesity: NHANES 2003–2006. Environmental Research, 111(6), 825–830.Carwile, J. L., et al. (2011). Canned soup consumption and urinary bisphenol A: A randomized crossover trial. JAMA, 306(20), 2218–2220.Centers for Disease Control and Prevention (CDC). (2004). Fourth National Report on Human Exposure to Environmental Chemicals.Gao, X., et al. (2020). Urinary bisphenol A and mortality risk. JAMA Network Open, 3(8), e2011620.Lang, I. A., et al. (2008). Association of urinary bisphenol A with medical disorders and laboratory abnormalities in adults. JAMA, 300(11), 1303–1310.Manikkam, M., et al. (2013). Epigenetic transgenerational inheritance of disease. PLOS ONE, 8(1), e55387.Mustieles, V., et al. (2015). Bisphenol A and neurodevelopmental outcomes in children. Environmental Health Perspectives, 123(7), 689–695.Peretz, J., et al. (2014). Bisphenol A and reproductive health. Environmental Health Perspectives, 122(8), 775–786.Rochester, J. R., & Bolden, A. L. (2015). Bisphenol S and F: A systematic review. Environmental Health Perspectives, 123(7), 643–650.Snijder, C. A., et al. (2013). Fetal growth and prenatal exposure to bisphenol A. Environmental Health Perspectives, 121(3), 393–398.World Wildlife Fund (WWF). (2019). No Plastic in Nature: Assessing Plastic Ingestion from Nature to People.University of Newcastle (Australia). (2019). Human Consumption of Microplastics.Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.
Projectionist Lance Carwile explains how he has been a programming consultant with CAPA and their Summer Movie Series about as long as he has been involved in Cinevent and the Columbus Moving Picture Show. Also we spotlight Dayton's Ralph Byrd.
Brandon Carwile of Packers Wire joins Wisconsin Sports Weekend to discuss some surprising Packers in the Pro Bowl, and just how important the Week 18 matchup against the Bears really is for Green Bay.
We are called to trust God with every aspect of our lives, recognizing that our trials are not without purpose. They shape our character and deepen our faith. As we face our own thorns, let us ask God how He can use them for His glory, rather than simply asking for their removal.
Buddy Pearson meets with the Chief Academic Officer Bridgett Carwile from the Putnam County School System. They talk about different federal programs that fund the school system, monitoring of funds, compliance, and more! Listen to the latest Local Matters Podcast… Presented by Office Mart Visit them at 215 S Jefferson Ave in Cookeville to see what they can do for your office News Talk 94.1 · Presented By Office Mart
Join us for the next episode of The MisFitNation Show as we welcome back Tom Kilgannon, president of Freedom Alliance, and Reese Carwile, Gold Star Daughter and rising senior at the University of Mississippi. Tom shares insights from his 25 years of leadership at Freedom Alliance and his role on the National Commission on Military, National and Public Service. Reese discusses her journey as a Freedom Alliance Scholarship Fund recipient, honoring her father's legacy and her pediatric or orthopedic care aspirations. Tune in for a heartfelt conversation about sacrifice, service, and the importance of supporting our military families. https://freedomalliance.org/
Nghe trọn nội dung sách nói Kỷ Luật Và Tự Do trên ứng dụng Voiz FM: https://voiz.vn/play/2645 Với cuốn sách "Kỷ luật và tự do", tác giả Ernie Carwile đã giới thiệu ba phạm trù quan trọng liên quan đến sự thành bại của mỗi người trong cuộc sống, đó là: thái độ, sự kiên trì và tinh thần chấp nhận bản thân. Thưởng thức những câu chuyện đầy thú vị của ông và những câu danh ngôn bất hủ ông sưu tầm được, chúng ta sẽ nhận ra những thông điệp đầy giá trị. Sách gồm 3 chương với những truyện ngắn khác nhau nhắn nhủ bạn đọc những bài học ý nghĩa trong cuộc sống. Quyển sách này như một sự xâu chuỗi những yếu tố căn bản giúp con người sống vui và sống hạnh phúc. Chúng ta có thể xem mỗi yếu tố vừa là một quá trình chuyển tiếp cho nhau đồng thời cũng vừa là sự kết nối, đan cài vào nhau, tạo thành con thuyền vững chắc đưa ta đến những bến bờ khát vọng... Tại ứng dụng sách nói Voiz FM, sách nói Kỷ Luật Và Tự Do được đầu tư chất lượng âm thanh và thu âm chuyên nghiệp, tốt nhất để mang lại trải nghiệm nghe tuyệt vời cho bạn. --- Về Voiz FM: Voiz FM là ứng dụng sách nói podcast ra mắt thị trường công nghệ từ năm 2019. Với gần 2000 tựa sách độc quyền, Voiz FM hiện đang là nền tảng sách nói podcast bản quyền hàng đầu Việt Nam. Bạn có thể trải nghiệm miễn phí đa dạng nội dung tại Voiz FM từ sách nói, podcast đến truyện nói, sách tóm tắt và nội dung dành cho thiếu nhi. --- Voiz FM website: https://voiz.vn/ Theo dõi Facebook Voiz FM: https://www.facebook.com/VoizFM Tham khảo thêm các bài viết review, tổng hợp, gợi ý sách để lựa chọn sách nói dễ dàng hơn tại trang Blog Voiz FM: http://blog.voiz.vn/ --- Cảm ơn bạn đã ủng hộ Voiz FM. Nếu bạn yêu thích sách nói Kỷ Luật Và Tự Do và các nội dung sách nói podcast khác, hãy đăng ký kênh để nhận thông báo về những nội dung mới nhất của Voiz FM channel nhé. Ngoài ra, bạn có thể nghe BẢN FULL ĐỘC QUYỀN hàng chục ngàn nội dung Chất lượng cao khác tại ứng dụng Voiz FM. Tải ứng dụng Voiz FM: voiz.vn/download #voizfm #sáchnói #podcast #sáchnóiKỷLuậtVàTựDo #ErnieCarwile
Laura Carwile presents her case for murder charges against Eva Millard for the murder of her daughter Olivia Soto. Support the show
Case against Eva Millard for the charge of murder in first degree for the death her daughter Olivia Soto as told by Chris Carwile. Support the show
This episode features Brandon Carwile, Regional Director of Experience Design at IU Health. Here, he discusses experience design and what it means, staying focused on the patient, the importance of asking for patient feedback, and more.
Meet the Ohio mother taking on the powers that be for medical marijuana for autism: Tiffany Carwile, who seems to never sleep.For the third year in a row, the Ohio Medical Board has refused to approve autism spectrum disorder as one of the state’s 25 qualifying conditions for medical marijuana. So Carwile is taking her arguments, based on science and experience, to Ohio’s legislators and governor. Carwile, president of the Autism Alliance of Ohio, said the most recent round of negative responses from the Ohio Medical Board was disheartening but “failure is not an option, for me or for my son.” Carwile’s 7-year-old son Jaxsyn was diagnosed with severe low-functioning autism in 2016.
This episode features Brandon Carwile, Regional Director of Experience Design Application at IU Health West in Lafayette, Ind. Here, he joined the podcast to talk about caregiver wellness and the trends in the healthcare workforce. He also discussed why it's so important for aspiring leaders to understand the motivation behind their desired ascension to top roles.
Cosmic conversations with magical beings for the purpose of embodying unity consciousness on Earth. I hope you are enjoying these conversations and I hope you are encouraged by hearing others' journeys as we bring the great awakening and move into the new earth. Kari Carwile (pronounced carry car-while). Kari ranches with her husband Randy in central Texas. Her passion is to see people awaken to who they truly are and to see them awaken to the massive power they hold within. Her greatest achievement as well as desire is blazing a path for others to be their authentic selves and to follow their own journey and their own truth. You can connect with Kari on FB https://www.facebook.com/kcarwile1 If you would like to share your experiences with the world in an interview like this, for the purpose of expanding the collective consciousness, please do connect with me directly To be notified of future articles & posts, please subscribe to my channel, and look for me on social media platforms @blackswansibyl & on your favourite podcast platform. You can connect with me at www.blackswansibyl.com --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/blackswansibyl/support
Jennifer Carwile talks about Finding Your Voice in America Today. A juried art show showcasing the provocative work of 40 artists from around the country
This week we take a hard look a Autism. Guest Tiffany Carwile successfully submitted autism to the Ohio Board of Pharmacy for consideration to be added as a qualifying condition for medical cannabis. This conversation gets personal as Host Curtis Perea and Guest Tiffany Carwile discuss their own struggles and triumphs with autism in the home as both of their sons have autism. As we await the Boards decision, you can help take help. Go to considercannabisnow.com to get a sample email and real email addresses of the board members. Send them a message and help the Ohio Autistic Community gain access.
Through studying Jesus’ call of Matthew, we will see the call of discipleship that Christ has placed on every believer’s life.
Through studying Jesus and the Paralytic, we will see the absolute authority Jesus has to forgive us and to cleanse us.
Jesus has all authority...over sickness, over nature, over demons and over us. He has authority over our relationships, finances, livelihood, hopes, dreams. Through studying Jesus’ authority over demons, we will see the need to respond to Christ’s authority in every area of our lives...and the danger of rejecting the authority of Christ.
Everything points to the gospel. Through studying Jesus’ authority over nature, we see a connection to Jonah and how Jesus is the greater Jonah….and ultimately is the only one who we can place our faith in.