Podcasts about ASD

There are big developments for Amazon resellers happening right now!   Here's a breakdown of what we cover on today's episode:   The world's first SOURCING to SHIPPING software is replacing loads of other tools! Get it for $1 for 30 days here (includes an onboarding session) 3pmercury.com/thrity The best "on screen calculator" for Amazon sellers is also the only FREE, fully functioning tool! This is the greatest freebie ever for Amazon sellers! 3pmercury.com/extension A VP at the largest trade show in the U.S. was just on our podcast telling us why TheProvenConference.com + ASD is the biggest event of the year for sellers! We are doing our bootcamp again starting July 21st - you MUST seen the results our students got last week the first time we did this. Register and see their results here: SilentJim.com/bootcamp For years we've ONLY offered one-on-one coaching, but we now offer GROUP TRAINING as well. Set up a call to discuss this here: SilentJim.com/bookacall   Watch this episode on our YouTube channel here: https://youtu.be/m132Q3Ls4dY   Show note LINKS:   3PMercury 30 day FULL ACCESS $1 trial with a training session - 3pmercury.com/thirty   Get the 3PMercury chrome extension (on screen calculator) free here - 3pmercury.com/extension   August 25-27th - TheProvenConference.com August 24 Pre-event one day "laptops open" workshop: TheProvenConference.com/mbw   SilentJim.com/bootcamp  - Jimmy Smith's 3 Day workshop!   ProvenAmazonCourse.com - The comprehensive course that contains ALL our Amazon training modules, recorded events and a steady stream of latest cutting edge training, including of course the most popular starting point, the REPLENS selling model. The PAC is updated free for life!   SilentJim.com/kickstart  - If you want a shortcut to learning all you need to get started, then get the Proven Amazon Course and go through Kickstart.   SilentSalesMachine.com - Text the word "free" to 507-800-0090 to get a free copy of Jim's latest book in audio about building multiple income streams online (US only) or visit SilentJim.com/free11   SilentJim.com/bookacall - Schedule a FREE, customized and insightful consultation with my team or me (Jim) to discuss your e-commerce goals and options.   My Silent Team Facebook group. 100% FREE! Facebook.com/groups/mysilentteam - Join 83,000 + Facebook members from around the world who are using the internet creatively every day to launch and grow multiple income streams through our exciting PROVEN strategies! There's no support community like this one anywhere else in the world!        

Autism and Diagnosis Metabolites and Phenotypes In a brand new paper entitled. “Elevated Microbially-Derived Metabolites in Autism: A Possible Diagnostic Screening Test for a Distinct ASD Phenotype,” Dr. Flynn and colleagues investigated whether specific urinary metabolites produced by intestinal microbes could serve as predictive biomarkers for autism spectrum disorder. The study proposes that a large subset of children with autism may represent a biologically distinct phenotype characterized by markedly elevated microbial metabolites, which the authors term ASD-MDM (Autism Spectrum Disorder associated with Microbially-Derived Metabolites). The investigators analyzed urine samples from 52 children with ASD and 47 typically developing (TD) controls, ages 2–11 years. They measured microbial metabolites derived primarily from phenylalanine metabolism, tryptophan metabolism, and yeast metabolism. These were chosen because decades of autism, microbiome, and metabolic research have repeatedly implicated abnormalities in microbial metabolism of aromatic amino acids, especially phenylalanine and tryptophan, along with evidence of elevated fungal/yeast metabolites in subsets of children with ASD. The findings were striking. Children with ASD demonstrated significantly higher concentrations of many microbial metabolites than controls. Some metabolites were elevated by hundreds to thousands of percent, and in certain children concentrations were reported to be 100–1000 times higher than the highest levels observed in any control participant. Twenty-three of twenty-four measured microbial metabolites were higher in ASD participants. Ninety percent of the ASD participants (45 of 50) had one or more extremely elevated MDMs. Particularly notable were elevations in compounds related to p-cresol, p-cresol sulfate, phenylacetylglutamine, indole derivatives, and arabinitol, suggesting abnormalities in microbial metabolism involving aromatic amino acids and yeast overgrowth.... Also, Inflammation and Allergy. Enjoy, Dr. M

EPISODE 162TWO DADS WHO CONNECTED WITH UNIQUELY HUMAN INTERVIEW BARRY. WITH BRAD BROYLES AND NATHAN PALMER, FROM THE POLARIS CONNECTIONThis episode is a replay of The Polaris Connection, an autism parenting podcast hosted by Brad Broyles and Nathan Palmer. In this episode, they interview Barry with specific attention given to how Uniquely Human has had a positive impact in the way they see their children and support their development. Brad and Nathan are also the founders of Polaris Academy. The podcast offers advice, expert insights, and real-life stories to help families of neurodivergent children navigate special education, therapies, and daily life.Learn more on our website!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

  35,000+ people will be at the largest trade show in the US at the same convention center as where our community is gathering next month! The organizers of that massive event have invited our leadership team to be the on-site E-commerce experts and trainers! It's a huge honor that speaks very highly of the reputation and results our team gets consistently for our students and clients!   In business, quality relationships equal opportunity. There's no better way to establish and grow those high impact relationships than to attend LIVE EVENTS!   TheProvenConference.com event is coming up fast! We hope you plan to join us in Vegas at one of the largest convention centers in the world for our annual gathering of business building warriors!     Today we sit down with a VP at ASD who tells who should attend this event and what you can expect if you come to the combo event featuring ASD and TheProvenConference August 25-27th, 2026.   Get all details from TheProvenConference.com   Watch this episode on our YouTube channel here: https://youtu.be/D31cGmShCb4   Show note LINKS:    ASD ASDlive.com   August 25-27th: TheProvenConference.com TheProvenConference.com/scholarship August 24 Pre-event one day "laptops open" workshop: https://theprovenconference.com/mbw   ProvenAmazonCourse.com The comprehensive course that contains ALL our Amazon training modules, recorded events and a steady stream of latest cutting edge training, including of course the most popular starting point, the REPLENS selling model. The PAC is updated free for life!   SilentJim.com/kickstart  - If you want a shortcut to learning all you need to get started, then get the Proven Amazon Course and go through Kickstart.   SilentSalesMachine.com - Text the word "free" to 507-800-0090 to get a free copy of Jim's latest book in audio about building multiple income streams online (US only) or visit SilentJim.com/free11   SilentJim.com/bookacall - Schedule a FREE, customized and insightful consultation with my team or me (Jim) to discuss your e-commerce goals and options.   My Silent Team Facebook group. 100% FREE! Facebook.com/groups/mysilentteam - Join 83,000 + Facebook members from around the world who are using the internet creatively every day to launch and grow multiple income streams through our exciting PROVEN strategies! There's no support community like this one anywhere else in the world!   Today's guest: Stephanie Beringhele  

Dr. John Gaitanis, a pediatric neurologist, joins Shannon to discuss common misconceptions about ASD and Motor disorders.  Leucovorin and metabolic interventions are discussed.  The jargon of the day is Methylation Cycle. 00:00 Introduction & Guest Preview 02:27 Autism Live Updates, Podcast & Community Resources 06:31 The Mission of Autism Live & Supporting the Autism Community 09:52 Jargon of the Day: What Is the Methylation Cycle? 13:54 Methylation, Detoxification & Autism Explained 16:22 Meet Pediatric Neurologist Dr. John Gaitanis 18:18 Is Autism Really One Condition? Rethinking the Spectrum 22:04 Autism Phenotypes, Brain Regions & Personalized Care 27:46 Medical Bias, Diagnostic Labels & Presuming Intelligence 32:21 Autism, Healthcare Discrimination & Advocacy for Non-Speakers 36:33 What Is MEDMAPS? Root Cause Medicine Explained 37:43 Developmental Regression, Inflammation & Methylation Dysfunction 46:20 Leucovorin, Folate Deficiency & Autism Treatment Options 53:50 Glutathione, B12, Gut Health & Systems Biology Approaches 57:15 Whole-Body Medicine, Brain Health & Final Takeaways

Dr. John Gaitanis, a pediatric neurologist, joins Shannon to discuss common misconceptions about ASD and Motor disorders.  Leucovorin and metabolic interventions are discussed.  The jargon of the day is Methylation Cycle. 00:00 Introduction & Guest Preview 02:27 Autism Live Updates, Podcast & Community Resources 06:31 The Mission of Autism Live & Supporting the Autism Community 09:52 Jargon of the Day: What Is the Methylation Cycle? 13:54 Methylation, Detoxification & Autism Explained 16:22 Meet Pediatric Neurologist Dr. John Gaitanis 18:18 Is Autism Really One Condition? Rethinking the Spectrum 22:04 Autism Phenotypes, Brain Regions & Personalized Care 27:46 Medical Bias, Diagnostic Labels & Presuming Intelligence 32:21 Autism, Healthcare Discrimination & Advocacy for Non-Speakers 36:33 What Is MEDMAPS? Root Cause Medicine Explained 37:43 Developmental Regression, Inflammation & Methylation Dysfunction 46:20 Leucovorin, Folate Deficiency & Autism Treatment Options 53:50 Glutathione, B12, Gut Health & Systems Biology Approaches 57:15 Whole-Body Medicine, Brain Health & Final Takeaways

Dr. Takon has 23 years of clinical experience assessing children for ADHD, ASD, tics, FASD and epilepsy. She's passionate about helping parents and professionals in communities, understand neurodiversity more clearly. As host of the "Early Intervention Matters" podcast, she regularly creates educational content on child development, early assessment, diagnosis and practical support for neurodivergent children and their families.

Các nhà nghiên cứu đã xem xét 124.333 anh chị em ruột và không tìm thấy bằng chứng nào cho thấy những bà mẹ dùng paracetamol khi mang thai có nhiều khả năng sinh con mắc chứng rối loạn phổ tự kỷ (ASD) hoặc rối loạn tăng động giảm chú ý (ADHD).

This episode is brought to you by the 2026 iTnews State of Security report and Brennan. Stay tuned to the end to hear from Peter soulsby, the director of cyber security and government at Brennan, as he discusses how AI is changing the threat landscape for organisations, but also how visibility can help cyber security practitioners move forward in enabling their organisations to embrace the technology and continue to redefine how work gets done.Hello and welcome to the iTnews Podcast. Our guest this fortnight is Chris Horlyck, head of cyber security resilience at the Australian Cyber Security Centre (ACSC) within ASD.Chris sat down with iTnews recently to discuss the planned changes to the Essential Eight, including its planned replacement with a new Essentials series.There's been a lot of discussion out in the industry since we first published our story in late June.Here, iTnews editor Ry Crozier and our security specialist Juha Saarinen talk to Chris to unpack the changes with Essentials, as well as recent changes to the Information Security Manual or ISM, and how these might also be reflected within the Essentials.

What do button-trained dogs, a German horse, and nonverbal disabled people have in common?Cards:This Documentary is Actually Dangerous:https://www.youtube.com/watch?v=glhXOHpBoMkSources:How do soundboard-trained dogs respond to human button presses? An investigation into word comprehension: https://tinyurl.com/28gpwj8vThe “Clever Hans Phenomenon” revisited: https://tinyurl.com/26zb7vmcBarnum effect: https://tinyurl.com/gs77vnlSoundboard-trained dogs produce non-accidental, non-random and non-imitative two-button combinations: https://tinyurl.com/2ccfukyhFacilitated Communication, Neurodiversity, and Human Rights: https://tinyurl.com/2ytq4svkSystematic review of facilitated communication 2014–2018 finds no new evidence that messages delivered using facilitated communication are authored by the person with disability: https://tinyurl.com/2brv58urFacilitated Communication and Authorship: A Systematic Review: https://tinyurl.com/2ykrp2u2Relations between language, non-verbal cognition, and conceptualization in non- or minimally verbal individuals with ASD across the lifespan: https://tinyurl.com/2yvj7qdaBecome a supporter of this podcast: https://www.spreaker.com/podcast/viced-rhino-the-podcast--4623273/support.All my various links can be found here: http://links.vicedrhino.comThis content is CAN credentialed, which means you can report instances of harassment, abuse, or other harm on their hotline at (617) 249-4255, or on their website at creatoraccountabilitynetwork.org

“And He (Jesus) awoke and rebuked the wind and said to the sea, “Peace! Be still!” And the wind ceased, and there was a great calm.” -Mark 4:39   Welcome to The Adoption & Foster Care Journey—a podcast to encourage, educate and equip you as you care for children in crisis through adoption, foster care and kinship care.   On this episode host Sandra Flach talks with returning guest favorite, Dr. Jerrod Brown. Dr. Brown has 6 PhD's and specializes in topics related to autism spectrum disorder (ASD), fetal alcohol spectrum disorder (FASD), confabulation, suggestibility, trauma and other life adversities, alexithymia, executive dysfunction, criminal recidivism, traumatic brain injury (TBI), and youth firesetting. You can check out his full bio on our website along with dozens of our bonus episodes feating Dr. Brown.   Here Dr. Brown unpacks the prevalence of migraine headaches among children with adverse childhood experiences (ACEs). Listen in or watch on our YouTube channel to learn risk factors, symptoms, and lifestyle medicine choices to improve outcomes.   You can find episode 539 wherever you get your podcasts!    Please be sure to subscribe to the podcast, leave a review, and share it on your social media.   Links mentioned in this episode: Dr. Jerrod Brown's Email See Available Trainings The Adoption & Foster Care Journey AFCJ on YouTube justicefororphansny.org justicefororphansny.org/hope-community     Email:  sandraflach@justicefororphansny.org sandraflach.com Soul Care Saturday—52 Devotions for Foster and Adoptive Moms Orphans No More—A Journey Back to the Father book on Amazon

Since the 1700s we have described this condition in the language of character. Lazy. Undisciplined. Careless. As recently as 2023, an Australian parliamentary inquiry heard the same words still follow people through their lives. Lindy Hadges explains why a condition that sits in the brain attracts shame that an identical shortfall in the pancreas never would, and what happens the moment someone stops believing the story they were told about themselves. View the ADHD Cake model: https://performanceintelligence.com/wp-content/uploads/2026/05/ADHD-Cake-of-Understanding.pngFind out more about the ADHD Foundation: https://adhdfoundation.org.au/about-usConnect with Lindy: https://ccaa.net.au/practitioner/200102-14/ Use Code "PQPODCAST10" to get 10% off your Lumo Coffee order:https://lumocoffee.com/ Interested in sharing your story? Email Producer Shannon at support@performanceintelligence.com today with your story and contact details. Learn more about Andrew and Performance Intelligence: https://performanceintelligence.com/Find out more about Andrew's Keynotes : https://performanceintelligence.com/keynotes/Follow Andrew May: https://www.instagram.com/andrewmay/Watch the Performance Intelligence Podcast on Youtube: https://www.youtube.com/@performanceintelligencepodcastIf you enjoy the podcast, we would really appreciate you leaving a short review on Apple Podcasts, Spotify or Google Play. It takes less than 60 seconds and really helps us build our audience and continue to provide high quality guests.

EPISODE 161BEING “PATHOLOGICALLY GENUINE”: A DISCUSSION WITH DR. JIM COLEMANJim Coleman, a semi-retired biology professor has had an amazing journey. He discusses his late diagnosis as an autistic person and his journey from feeling like “a banana slug transported into the Mojave Desert” to embracing his neurodiversity. He shared his teaching philosophy of helping every student reach their full potential, noting that over 200 of his students have disclosed being neurodivergent to him. Jim also discussed his work with his therapy dog Brea, who visits schools for autistic children and a community center for people recovering from mental illness.Find out more on our website!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Send us Fan MailWhen life doesn't look the way you once planned, how do you decide what matters most? What does success look like when your priorities change?Deb sits down with Rowena Brykin to discuss her family's move from Abu Dhabi to Canada, her decision to leave a successful career to become a homemaker, and the realities of raising four boys, including triplets, two of whom are autistic - one profoundly so.Together they explore caregiving, marriage, identity, and the invisible load many parents carry while creating a life that better supports their family's needs.A powerful conversation about redefining success, choosing peace, and discovering that sometimes the greatest act of love is simply being present.Real parents. Real stories. Because it takes a village to raise a child — and a community to raise their parent.WATCH THIS EPISODE on YOUTUBE HEREThe Guest: ROWENA BRYKINIG - @mama_brykin  (Main)       @mama_uniquorns TIKTOK - @victoriagood.ca"I NEED MY SASS BACK"  Music Video YouTubeSpotifyApple Music IG - @sassandsmalls (Main)        @sassandsmalltalkpodcastFB/TIKTOK/WEBSITESUBSCRIBE YOUTUBEListen HERERequests HERERATINGSIf you're a parent/caregiver carrying an invisible load & like what you hear? Please share and rate us 5 Stars  BYE BYE BURNOUTMY GO-TO for Cortisol-balancing, Gut-healing, Stress Resillience:  "HAPPY" DRINK $10 OFF 

As a holistic and functional psychiatrist, I see many people who are highly sensitive. Most are deep divers into information and able to connect a lot of dots. Many are gifted. Many struggle with overwhelm and low stress tolerance. Some struggled with anxiety, inner tension, or feeling “too much” for as long as they can remember. Some feel different - that they don't fit in.As a holistic and functional psychiatrist with over twenty years in practice, I've worked with thousands of highly sensitive adults and children. Most are deep divers into information, able to connect a lot of dots — many are gifted. And yet many struggle with overwhelm, low stress tolerance, anxiety, or inner tension that has been there for as long as they can remember. Many feel different, like they don't quite fit in. What I've found is that sensitivity itself is rarely the problem — it's the seeming vulnerability to brain-related or physical conditions. Over the years I've found three different models to be especially useful in explaining some of the vulnerabilities and the strengths of those of us who are highly sensitive: Dr. Elaine Aron's work on the Highly Sensitive Person (HSP), the nutritional medicine concept of Pyrrole Disorder, and Dr. Sharon Meglathery's RCCX Theory. Each looks at a similar group of traits through a different lens — psychological, biochemical, and genetic, respectively.Before I start, I want to emphasize that sensitivity is not a pathology or a diagnosis. It is actually a trait that has existed across human history for a reason. My goal is not to pathologize it, but to understand it — and to offer tools to those who have these traits but who are struggling with a condition more prevalent in those with these traits. As I go through these three frameworks, the overlap will be obvious and I'll highlight what each of these has to offer that the others don't.What You'll Learn* The HSP model provides validation and a language for sensitive individuals.* Pyrrole Disorder involves an overproduction of pyrroles, leading to nutrient depletion of nutrients critical for neurotransmitter functioning.* Pyrrole Disorder is common in brain-related conditions.* RCCX Theory connects genetic vulnerabilities to sensitivity and chronic illness.* Stress amplifies the experiences of highly sensitive individuals.* Understanding these models can lead to effective treatment options.* There are meaningful paths forward for those who are highly sensitive.Chapters* 00:00 Understanding High Sensitivity* 02:26 The Highly Sensitive Person (HSP) Model* 10:23 Exploring Pyrrole Disorder* 18:18 RCCX Theory Explained* 30:11 Intersecting Models: HSP, Pyrrole Disorder & RCCX Theory* 34:40 Conclusion and Path ForwardI. THE HIGHLY SENSITIVE PERSONIn the early 1990s, psychologist Dr. Elaine Aron identified a personality trait she called Sensory Processing Sensitivity (SPS) — and the people who score high in it she called Highly Sensitive Persons, or HSPs.This is not a diagnosis. It is a trait, present in roughly 15–20% of the population. It has been found across more than 100 species — from fruit flies to primates. This tells us it is evolutionarily conserved — it confers survival advantages. In any social group, having members who are wired to notice subtle cues, process information deeply, and detect threats before others do is extremely valuable. Fitting with this, many of these individuals, who also struggle with complex chronic health issues are considered the “canaries in the coal mine” since their bodies react to environmental triggers (environmental toxins, chemicals, or stressors) long before the rest of the population.Dr. Aron captured the core features of this trait in an acronym she called DOES:D — Depth of processing: HSPs think deeply, reflect before acting, and notice subtleties that others miss.O — Overstimulation: Because they process so thoroughly, HSPs reach their threshold more quickly in high-stimulation environments.E — Emotional reactivity and Empathy: HSPs feel emotions intensely and are highly attuned to the emotions of those around them.S — Sensitivity to subtle stimuli: They pick up on things — in their environment, in social dynamics, in the body — that others simply don't register.As you can see, traits that are super powers, can become liabilities. The deep diver who loses sight of the big picture. The empath who absorbs everyone else's energy as their own energy becomes depleted. The person who withdraws from the world because the stimulation has simply become too much.HSP ResearchBeyond the clinical observations, there is now a growing body of neuroscience and genetic research supporting this trait. There is evidence that the brains of sensitive people are doing more, processing more and feeling more.fMRI studies (Acevedo, Aron et al., 2014) have shown that when HSPs view emotional images — particularly photos of loved ones expressing happiness or sadness — their brains show significantly greater activation in regions associated with awareness, empathy, and sensory integration.Twin studies show that Sensory Processing Sensitivity (SPS) as defined by Dr. Aron is approximately 47% heritable. Small studies as opposed to large genome wide studies have focused on genetic variants involving dopamine and serotonin systems, such as a serotonin transport gene, a dopamine receptor gene, and COMT, which codes for the enzyme that metabolizes dopamine and norepinephrine.While this hints at a biochemical dimension, the HSP framework doesn't address this as directly as the other two models I'll discuss, nor does it explain the higher prevalence of physical health conditions in those who are highly sensitive.Research published in 2026 (Matsuzawa et al.) found that individuals high in SPS had substantially higher rates of depression (13.8%), anxiety disorder (10.5%), and developmental disorders, such as ADHD and ASD, compared to the general population.Despite this overlap with developmental disorders: unlike, ADHD, HSPs typically have excellent concentration in quiet environments. And unlike the social deficits described in ASD, HSPs tend to have heightened social attunement. They often feel too much of what's happening in social situations, not too little, even if they respond awkwardly at times.Research shows that high sensory processing sensitivity is associated with more frequent physical symptoms — back pain, fatigue, digestive issues, frequent illness.What This Framework OffersThe HSP model has given millions of people validation and a language for these traits that has allowed them to shift from “what is wrong with me” to “this is how I am wired.”It also offers an evolutionary reframe. High sensitivity is not a mistake and is not pathologic. It is a feature of the human population that has served us.What it doesn't offer is a biological explanation for why some sensitive people suffer so acutely — or a path toward biochemical intervention. II. PYRROLE DISORDERPyrrole disorder is a biochemical imbalance that has been recognized for decades, though it remains largely unknown in mainstream psychiatry. It involves an overproduction of pyrroles — metabolic byproducts that, on their own, are not a problem. When they are high, however, they can result in a depletion of zinc, B6 and a few other nutrients.First identified in the 1950s and first treated with zinc and B6 in the 1980s, pyrrole disorder is one of the most common nutrient imbalances found in brain-related conditions — and one of the most treatable. Yet most people who have it have never heard of it. I learned about pyrroles in 2014 when I first trained with the Walsh Research Institute.The Importance of Zinc, B6 & MagnesiumVitamin B6 is required to synthesize dopamine, serotonin, and GABA — three of the most critical neurotransmitters for mood regulation, anxiety, and stress response. Zinc plays a profound role in the central nervous system, the immune system, gastrointestinal tract (which we now know has its own significant influence on brain health) and connective tissue (joints and skin).Pyrrole Disorder Traits & SymptomsThe most consistent feature is low stress tolerance. People with elevated pyrroles are often described as those for whom life seems harder than it should be, every transition can be destabilizing and every large group or new environment feels like too much.The overlap with the HSP profile is striking, but here, we start to see not only traits, but symptoms.- Socially anxious, shy, or fearful since childhood, with severe inner tension- Sensitive to bright light, loud noises, textures, and odors- Avoids crowds, strangers, and new situations- History of reading difficulty- Poor short-term memory- Underachievement- Irritability, mood swings, bouts of depression- Tends to stay up late; little or no dream recall; morning nausea- White spots on fingernails; very dry skin; stretch marks; poor wound healing- Joint pain- Frequent infections or autoimmune tendenciesMost people with pyrrole disorder don't have all of these symptoms — but the inner tension, the high sensitivity, and low stress intolerance are very common.What the Data ShowsThe Walsh Research Institute has collected data on over 30,000 patients. Elevated pyrroles were found in:* 18% of those with ADHD* 24% of those with depression* 28% of those with behavioral disorders* 35% of those with autism* 35% of those with bipolar disorder* 30% of those with schizophrenia* 12% of those with PTSDAnd in only 8% of healthy controls — meaning those with no psychiatric diagnosis.What Causes Pyrrole Disorder?For many, there appears to be a genetic component, but for others, pyrroles appear to have increased due to high physiologic or emotional stress. Examples include candida overgrowth or other forms of gut microbial imbalances, mold toxicity, heavy metals, chemical exposures, illness, emotional trauma, major life transitions or even growth spurts in children.What This Framework Brings UsRelative to the HSP framework, an understanding of pyrroles gives a specific, treatable biological mechanism. When zinc, B6, Magnesium and other nutrients are depleted, we know how the brain's neurotransmitter functioning is affected — and we know what to do about it.Treatment from a Walsh Research Institute trained practitioner typically involves a nutrient protocol of zinc (based on zinc and copper testing), B6 or its active form P5P, and other nutrients for pyrrole disorder and other nutrient imbalances identified. For many patients, a lifetime of chronic inner tension and fearfulness begins to shift within days to a couple of weeks of starting the nutrients.Treatment doesn't change one's personality, but it can improve social discomfort, overwhelm, the anxiety, the depression that has been layered on top of that sensitivity.Where zinc deficiency can impact a lot of the physical conditions that appear to be more common in those who are hypersensitive, it doesn't fully explain the significant hormonal, inflammatory, connective tissue symptoms and autoimmunity we see in many who are hypersensitive.III. RCCX THEORYRCCX theory has been proposed by Dr. Sharon Meglathery, MD — a psychiatrist and internist whose own complex health history (which is very similar to my own) led her to one of the most compelling explanations I've encountered for why hypersensitivity, neurodivergence, psychiatric conditions, MCAS (Mast Cell Activation Syndrome), EDS (Ehlers Danlos Syndrome), POTS (Postural Orthostatic Tachycardia Syndrome), CIRS (Chronic Inflammatory Response Syndrome) and/or CFS (Chronic Fatigue Syndrome) and autoimmunity tend to cluster together in certain individuals and families.RCCX refers to a module of four genes on chromosome 6. Three of them appear to be particularly important to our health, and two of those have very high rates of mutation.The Three Key Genes(1) TNXB codes for a protein involved in connective tissue. Variants range from subtle joint hypermobility to Ehlers-Danlos Syndrome. But connective tissue isn't just about joints — it's also about the permeability of the gut-blood barrier, the blood-brain barrier, and vulnerability to upper cervical (neck) instability, which can put tension on the vagus nerve and affect the entire autonomic nervous system.(2) CYP21A2 is the most important gene in the module when it comes to psychiatric conditions. It codes for 21-hydroxylase, an enzyme needed to convert 17-hydroxyprogesterone into cortisol. When there is a mutation — and there can be many, of varying degrees — the body may struggle to meet the demand for cortisol under stress. A weakness on this gene could have two primary effects:First — The theory holds that many people with CYP21A2 mutations, even without hypermobility, may develop what Dr. Meglathery calls a “brain wired for danger” — essentially, a nervous system calibrated toward threat detection from early in life, with minimal trauma required. A mutation on CYP21A2 may essentially result in relatively higher androgens impacting the amygdala — the brain's fear and emotional center. Studies have found that hypermobile individuals (who often carry TNXB mutations) have a larger-than-normal amygdala.Second — because of this mutation, the body may not be able to keep up with the body's need for cortisol (especially when under stress). This deficit causes the brain to release corticotropin releasing hormone (CRH) to signal the adrenal glands to produce more cortisol. CRH binds to mast cells and activates the immune system — leading to secondary brain inflammation. This is the inflammatory pathway that can result in a number of secondary health issues including MCAS, CIRS, POTS, CFS and more.(3) C4 is involved in immune response and autoimmunity, and has been linked to schizophrenia. This gene variant is not as common as the first two referenced, though I do see a number of families who also have autoimmunity impacting multiple family members.The CAPS Psychological ProfileDr. Meglathery uses the term CAPS — CYP21A2 Mutation Associated Neuropsychiatric Spectrum — to describe the psychological profile she has observed in people with this genetic vulnerability. These traits can exist long before any formal psychiatric diagnosis, and they are not inherently pathological. - Anxiety and over-arousal during times of stress — high adrenaline, insomnia, sometimes manic-like characteristics- Under-arousal during low-stress periods — leading to ADD presentations, compulsive behaviors, or thrill-seeking to raise arousal- High emotionality, sensitivity, and reactivity to environmental stimuli- Sensory processing difficulties — typically over-stimulation in loud or chaotic environments- A strong ability to read emotions in others, paired with social awkwardness in response- Easily affected by events others would consider minor — an offhand comment, a disturbing movie- A tendency toward nonconformity- Special abilities: gifted musicians, scientists, creatives, systems thinkers- Hyper-focus and obsession with areas of deep interest, often leading to remarkable accomplishments- High tenacity and determination, when not derailed by overstimulation or past trauma- Strong emotions — positive or negative — that can manifest as obsessional worrying, harm avoidance, OCD tendencies, or very high standards for self and othersDr. Meglathery also notes — and I have observed this clinically — that people with this profile tend to find each other through friendships, partnerships and marriage. They are drawn together by shared sensitivities, emotional depth, and intellectual gifts. This means children are likely to receive a tendency towards CAPS from both sides.Women who are appear to have CYP21A2 mutations often have a male-pattern finger length ratio — the ring finger longer than the index finger — a possible marker of androgen exposure during development.What RCCX OffersRCCX theory offers the broadest biological framework we have for understanding why sensitivity, psychiatric vulnerability, and complex chronic illness so often travel together in the same people and families. It connects the nervous system, the immune system, the hormonal system, and connective tissue under one genetic umbrella.It also points toward specific interventions: nervous system regulation (limbic retraining, vagal work), mast cell management, and addressing the downstream biochemical consequences of cortisol dysregulation.The limitation is that genetic testing for variants on the gene for 21-hydroxylase is not yet widely available, which is why this isn't a gene that you'll see referenced when it comes to HSP, though I would argue it is likely the most prevalent. RCCX remains a clinical theory — but one that explains the constellation of traits and symptoms of most of the people that I in my practiceIV. WHERE THESE MODELS INTERSECTWhere Might Pyrrole Disorder and RCCX Theory Meet?The symptom overlap is almost complete: poor stress tolerance, sensory sensitivities, anxiety, inner tension, connective tissue symptoms, frequent infections, autoimmune tendencies. Relatively low zinc would impact most of these shared symptoms, but there may be a potentially deeper connection.21-hydroxylase contains a pyrrole-like structure — heme — within it. Could a mutation resulting in abnormal 21-hydroxylase lead to a buildup of abnormal heme-like compounds, contributing directly to pyrrole disorder? This is not proven, but in an exchange about this with Dr. Meglathery, she indicated that she also believes there is a strong association, and the biochemical logic is compelling.This matters, because we know what helps pyrrole disorder. We have a treatment — treatment that can complement what RCCX theory makes evident — that the stress response has to be addressed.Stress (again from any cause - physiologic or emotional) is the great amplifier across all three models. Stress worsens the HSP experience, and tips the CYP21A2 mutation from manageable to destabilizing (through the hormonal consequences and the inflammatory cascade) and yes, it even causes pyrroles to increase.BRINGING IT TOGETHERFor someone who is highly sensitive, and struggling with brain related or physical symptoms or conditions, pyrrole disorder and even RCCX theory are worth considering because they offer tools and start to answer, “What Can We Do About It?”The three frameworks work together:The HSP model offers validation and language. It shifts the frame from deficit to difference. It reminds us that sensitivity is not pathology — it is a trait with evolutionary value, and it comes with great strengths.The Pyrrole model offers a treatable nutrient imbalance. It explains, at the neurotransmitter level, why stress hits harder for these individuals. Treatment doesn't take away the sensitivity; it lifts the weight that has accumulated on top of it.The RCCX model offers the broadest systems view. It connects the dots between what the body is doing — the immune activation, the hormonal dysregulation, the connective tissue involvement — and the psychiatric and psychological profile that tends to accompany it. It also provides additional tools: nervous system regulation, mast cell support, hormonal awareness.If any of this resonates — the sensitivity, the inner tension, the feeling of always being at the edge of overwhelm — please know that there are roots to explore and meaningful paths forward.If you are looking for someone trained by the Walsh Research Institute knowledgeable in assessing for and treating pyrrole disorder (and other common nutrient imbalances impacting brain health), or learning more about Dr. Aron's work on HSP and Dr. Meglathery's RCCX theory, I am providing those links below.And as always, I welcome your thoughts, experience and questions.Until next time,CourtneyAbout the AuthorDr. Courtney Snyder MD is a Holistic and Functional Child and Adult Psychiatrist who offers non-patient consultations to individuals and practitioners nationally and internationally in addition to her treatment practice serving FL, IN, KY, OH. Her educational content, shared through her website, Substack Newsletter, the Holistic Psychiatry Podcast and YouTube Channel reaches readers and listeners in over 160 countries.ResourcesWalsh Research Institute: walshinstitute.orgRCCX Theory — Dr. Sharon Meglathery: rccxandillness.comDr. Elaine Aron — The Highly Sensitive Person: hsperson.comOther Sources: Acevedo et al. 2014, “The Highly Sensitive Brain,” Brain & Behavior | Matsuzawa et al. 2026, Psychiatry & Clinical Neurosciences ReportsMedical Disclaimer:This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your physician for any medical issues that you may be having. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit courtneysnydermd.substack.com/subscribe

This week, Cyber Uncut looks at important tax time advice, a string of Aussie hacks that have exposed sensitive personal information, and the Australian Signals Directorate's decision to retire the Essential Eight. CPA Australia has a warning this tax time, and that is to be very aware of taking tax advice from AI chatbots and financial influencers. An AI hallucination could cost you real money, so this is something to pay attention to! It's been a terrible week for data breaches in Australia, with the NSW Rural Fire Service warning its members of a data breach, and a ransomware actor dumping teacher and student data from the Reynella East College breach onto the dark web. Right now, cyber criminals are no doubt combing through the data, making this breach one that parents should pay attention to. Finally, the ASD has said that, as good as the Essential Eight is, it's no longer fit for purpose in the AI age. Find out what's going to replace it, and then stay tuned for an update on the alleged distributed denial-of-service (DDoS) attack that took down a One Nation website a couple of weeks ago. Just another week in cyber security. Enjoy, The Cyber Uncut team

Send us Fan MailABA on Tap is proud to present Asia Johnson (Part 1 of 2):A two-pound baby in the NICU. A young mom in a demanding academic track. Years of sleepless nights, confusing behaviors, and a system full of waitlists and half-answers. Asia Johnson joins us to share the throughline that connects all of it-- learning how to advocate for her daughter, and then bringing that same urgency and empathy into the ABA field as an RBT and later a BCBA.In this pour of ABA on Tap, Mike, Dan and Asia  get real about what families feel after an autism diagnosis, especially when the people around them do not understand ASD, and when community stigma makes support harder to access. Asia breaks down why the five stages of grief are not just theory, but a practical tool for parent support and for clinicians who want to teach skills without ignoring the emotional load caregivers carry. We also talk about acceptance as a daily practice: redefining happiness, building structure, and choosing goals that protect dignity and independence.From masking and stimming to school accommodations and powerful self-advocacy, Asia gives vivid examples of what growing up autistic can look like for a level one pre-teen. Then we dig into culturally responsive ABA: dialect, identity, and why therapy must meet a child where they are rather than sanding down culture to fit a narrow idea of “proper.” Finally, Asia shares what she has seen when ABA goes wrong and why ethical leadership has to interrupt harmful clinic cultures before they reproduce.Enjoy this first pour, return for part 2, share this with a parent or clinician who needs it, subscribe and leave a review with your take. Tell us---what should ethical ABA protect first?Tune in, drink up and ALWAYS analyze responsibly.Support the show

Mikee P. and Jackson Muniz go after the Late Pick 4 on Tuesday, June 23rd. The bet carries a $1 minimum and has a $50,000 Guarantee. ASD also had $3 rolling Pick 3s on the card.

Mikee P. and Jackson Muniz go after the Late Pick 4 on Tuesday, June 23rd. The bet carries a $1 minimum and has a $50,000 Guarantee. ASD also had $3 rolling Pick 3s on the card.

Join Sue for an upcoming Live Virtual Workshop where you will learn from Sue practical tips & strategies to make a difference. ✅ Handwriting: Complex skill involving pencil grip and eye tracking simultaneously. ✅ Dysgraphia: Child knows what to write but cannot execute. ✅ Fine Motor: Spinning tops and squeeze balls strengthen children's grip. ✅ Accommodations: Pencil grips, shorter pencils, and color choice support students. ✅ Short Breaks: Alternate five minutes writing with gross motor activity. ✅ Visual Supports: Use topic sentences and mind mapping for structure. ✅ Whole Body: Posture, core strength, and eye tracking matter profoundly. Read more about this podcast in the show notes found via the link below suelarkey.com.au/handwriting-strategies-neurodiverse-learners Join the Facebook group specifically for this podcast www.facebook.com/groups/suelarkeypodcastcommunity/ Join my Neurodiversity Network suelarkey.com.au/neurodiversity-network/ Follow my Instagram account for regular tips www.instagram.com/sue.larkey/ To learn more about teaching or understanding ASD, please visit my website below. elearning.suelarkey.com.au

Send us Fan MailIn this episode of A Mother's Guide Through Autism, host Brigitte Shipman sits down with Maureen Brice and Dr. Nicole Dolan to explore a deeply profound side of caregiving: the parent's own nervous system, trauma history, and energetic frequency.When your neurodivergent child has a meltdown, does your own anxiety or anger immediately skyrocket? You are not alone. Maureen Brice and Dr. Nicole Dolan dive into why our children act as powerful mirrors, triggering unhealed parts of our own childhood conditioning. They share how shifting out of survival mode and consciously clearing your internal blocks can completely change the emotional climate of your home. If you are a mother feeling burnt out, exhausted, and stuck in a loop of reactive parenting, this conversation offers the roadmap, permission, and actionable energetic tools you need to heal your family from the inside out.In This Episode, You Will Learn:- How our children's behaviors unconsciously trigger past ancestral and childhood conditioning.- The science and energy of co-regulation—why your child feeds off your nervous system's internal state.- Practical strategies to recognize parental burnout and halt chronic fight-or-flight loops.- The power of releasing judgment to build a sustainable, compassionate home life.

On Neurotypical and Neurodivergent Relationships: A Discussion with Dr. Cindy ArielDr. Cindy Ariel is a psychologist specializing in neurodivergent and neurodivergent relationships, and in her discussion with Barry and Dave, she shares insights about the specific challenges and unique qualities of such relationships. Cindy emphasizes that successful relationships require both partners to focus on mutual compatibility rather than trying to fix the other person, and how allowing both partners to be authentic can deepen connection and understanding. Given that relationships are a huge part of Dave's work, he actively contributes his perspective to the discussion with Cindy.Learn more on our website!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

A recent study examines if the hyper focus people with ASD experience is similar to creative flow, and the results have been a huge vindication for autistic people.I look at the 2 phenomena, the results of the study and the RTA method used. It's a happy wee episode, finally. Grma xStudy name: “In a state of flow: A qualitative examination of Autistic adults' phenomenological experiences of task immersion”Inline G Merch ⭐️www.Inlineg.myshopify.comInline G Patreon ⭐️www.patreon.com/TheInlineGFlutePodcastInline G will ALWAYS be free of charge, but signing up to the Patreon helps let this podcast reach new heights, if you can afford it. You'll also get to ask questions to upcoming guests as well as get early access to some episodes. Or if you'd rather not spend money, subscribing to my YouTube channel and following me on Facebook, Instagram and TikTok is a HUGE way to support the podcast. It'll cost you nothing, and it really makes a difference to the algorithm gods. So please interact however you can; like, comment, or subscribe, and help keep this podcast lit xIntro music: Rhythm=Power by Spodo Komodo. Used with permission. All rights reserved by the creator.Chapters:00:00 - The Cheshire Cat03:35 - Autism Spectrum Disorder09:30 - Money, Money, Money11:41 - Reflexive Thematic Analysis15:24 - Vindication for ASD

As D.C. holds its Democratic primary, the polling leader is Janeese Lewis George, who wants new taxes on businesses, "childcare for all," and more. But President Trump warns that D.C. is ultimately under federal control. Plus, two Dan Sullivans running in Alaska? Here's another ranked-choice voting fiasco. Learn more about your ad choices. Visit megaphone.fm/adchoices

Join Sue for an upcoming Live Virtual Workshop where you will learn from Sue practical tips & strategies to make a difference. ✅ OCD vs Autism: autism celebrates identity, OCD only causes distress. ✅ Real Event OCD: invents false narratives around dim memories. ✅ The OCD Cycle: obsession, anxiety, compulsion, relief, then repeat. ✅ Breaking Compulsions: not doing them weakens the entire cycle. ✅ Compulsions vs Rituals: compulsions fear-based, rituals come from joy. ✅ Repetition Source: joy means encourage, fear means co-regulate. ✅ Living Around OCD: continue normal life despite intrusive thoughts. Read more about this podcast in the show notes found via the link below suelarkey.com.au/ocd-autism-classroom-strategies Join the Facebook group specifically for this podcast www.facebook.com/groups/suelarkeypodcastcommunity/ Join my Neurodiversity Network suelarkey.com.au/neurodiversity-network/ Follow my Instagram account for regular tips www.instagram.com/sue.larkey/ To learn more about teaching or understanding ASD, please visit my website below. elearning.suelarkey.com.au

How One Family Supported Their Son Through Severe Emotional Struggles, Developmental Challenges, and a Powerful Recovery JourneyThis week on the Natural Super Kids Podcast, we're sharing an incredibly raw and emotional conversation with mum Casey about her son Ashton's journey through severe behavioural challenges, mental health struggles, sleep issues, ADHD, anxiety and overwhelming family stress, and how things slowly began to change.We speak with Casey about the years where Ashton's aggression, emotional dysregulation, self-harm and physical health issues left the whole family in survival mode and how a combination of holistic health support, gut health interventions, psychological care and community support helped Ashton find his way back to himself.In this episode, we explore:How Ashton's sudden changes in behaviour, aggression, emotional outbursts and school struggles led to multiple diagnoses including ADHD, anxiety, depression and pathological demand avoidanceThe hidden physical health issues contributing to his mental and emotional state, including severe sleep deprivation, gut dysfunction and poor nutrient absorptionHow microbiome testing, targeted supplements, dietary changes and nervous system support helped improve Ashton's sleep, mood, emotional regulation and energyWhy community support, trusting parental instincts and taking small consistent steps can make such a powerful difference for families navigating complex challenges

Send us Fan MailWelcome to Season 5 of The Thriving & Surviving Podcast! Amanda's back, and she's got a lot to fill you in on. This first episode is a real, unfiltered life update on the three big things that have shaped the last little while: coming to terms with an ASD diagnosis and how it's reframed the way she sees herself and the world, the emotional rollercoaster of packing up and moving to a new home, and the wild, vulnerable journey of finally releasing an album. Expect plenty of honesty, a few laughs, and the usual reminder that you can be both thriving and surviving at the same time. Settle in - it's good to be back. Support the showFind us on instagram:@thethrivingandsurvivingpod_@coach_amandajaneWild Discount: AMANDALOVES CLICK HEREwww.estro-physiques.com.au

Mikee P grabs inthemoneypodcast.com contributor Rick Tangeman for a look at the Late Pick 4 for Assiniboia Downs on Tuesday, June 9th. ASD has a $1 Late Pick 4 with a $50,000 Guaranteed Pool and a 15% takeout. ASD also has $3 rolling Pick 3s.

Mikee P grabs inthemoneypodcast.com contributor Rick Tangeman for a look at the Late Pick 4 for Assiniboia Downs on Tuesday, June 9th. ASD has a $1 Late Pick 4 with a $50,000 Guaranteed Pool and a 15% takeout. ASD also has $3 rolling Pick 3s.

Join Sue for an upcoming Live Virtual Workshop where you will learn from Sue practical tips & strategies to make a difference. ✅ Core Understanding: Perfectionism in neurodivergent kids stems from anxiety, not standards. ✅ ADHD Perfectionism: Won't start, gives up quickly, fears failure intensely. ✅ ODD Perfectionism: Refusal and arguing mask deep vulnerability and control needs. ✅ PDA Perfectionism: Loss of control drives anxiety-driven demand avoidance. ✅ Autism Perfectionism: Rigidity and repetition needed for predictability and rightness. ✅ OCD Perfectionism: Checking behaviors prevent feared catastrophes from happening. ✅ Key Strategy: Tailor support by understanding each diagnosis's underlying drivers. Read more about this podcast in the show notes found via the link below suelarkey.com.au/perfectionism-in-neurodiverse-children Join the Facebook group specifically for this podcast www.facebook.com/groups/suelarkeypodcastcommunity/ Join my Neurodiversity Network suelarkey.com.au/neurodiversity-network/ Follow my Instagram account for regular tips www.instagram.com/sue.larkey/ To learn more about teaching or understanding ASD, please visit my website below. elearning.suelarkey.com.au

Sleep Disturbances in Autism and Neurodivergent Conditions: A Discussion with Dr. Beth Malow, MD, Neurologist and Sleep Disorder Expert Dr. Malow, discusses how sleep problems affect approximately 80% of individuals on the autism spectrum and family members, emphasizing that improving sleep can positively impact every aspect of an autistic person's life and the life of the family. She explained that sleep deprivation exacerbates existing challenges and can lead to irritability and impaired social communication, which are already core features of autism. Beth framed sleep as a “window” to help autistic individuals and families, contrasting this positive approach with the common tendency to focus on difficult behavioral patterns when sleep issues occur.Find out more on our website!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You can find the webinar on YouTube here. How do we communicate the gospel in a way that serves the listener?In this webinar episode, Larah explores a biblical theology of communication and introduces the LEARN framework, a practical approach for discipling autistic individuals and others impacted by disability. Drawing from the ministry methods of Jesus, Larah explains why communication is not primarily about the speaker, but about helping the listener understand and engage with truth.Throughout the episode, you'll learn how to listen before speaking, enter another person's world, assume competence, respond with curiosity and patience, and nurture relationships over time. Larah also shares practical examples for parents, church leaders, and volunteers, including case studies involving a nonverbal child, a teen with social challenges, and an adult seeking belonging within the church.Whether you're discipling your own child, serving in disability ministry, or simply seeking to communicate more effectively, this episode offers a gospel-centered framework that can transform the way you connect with others.In This Episode Why communication is a ministry to the listener Examples of how Jesus adapted His teaching methods The LEARN framework for disability discipleship Why flexibility is a ministry tool, not a compromise The importance of assuming competence Coaching volunteers to respond with curiosity instead of correction Building trust through long-term relationships Practical case studies for children, teens, and adults Using visuals, routines, and sensory supports in discipleship Strengthening the partnership between parents and churches Resources available to support gospel conversations at home and churchKey Takeaways Communication serves the listener, not the speaker. Effective discipleship begins with understanding before instruction. LEARN: Listen First, Enter Their World, Assume Less, Respond with Curiosity & Patience, Nurture Relationships. Behavior should not automatically be interpreted as lack of understanding. Small accommodations often create significant opportunities for gospel engagement. Trust is often the bridge that allows truth to be received. Parents and churches accomplish more when they work together. You don't have to do everything at once. Start small somewhere.Notable Quotes"You can't disciple someone you refuse to understand.""Flexibility is a ministry tool, not a compromise.""Assume competence until proven otherwise.""Seek understanding before solutions. Respond with curiosity and patience.""The truth travels best through trust.""Start small somewhere."Resources MentionedLetters to Lindsey: Seeing Your Child's Autism Diagnosis Through a Gospel Lens

Tom talks about ADHD, ASD, and OCD for like 15 minutes then the boys talk about Empress Sisi again. Róisín's vox pop segment about the Jimmydome finally makes its appearance, and of course we finish with the mailbag.   Shouts out to Jay for the pride month episode image/pfp. Shoot a message or leave us a voicemail (leave your name and pronouns): 267-371-7218 Find our bonus episodes and Discord on Patreon. Follow us on Bluesky:  Podcast Liam Tom  

Please let us know what you think of this podcast.In this podcast we chat with Carmela Miniscalo and Anna-Clara Reinholdson about their research which looks at speech sound ability in relation to language ability and non-verbal ability in Swedish pre-school children with ASD.The paper is:Miniscalco, C., Reinholdson, A.-C., Gillberg, C. & Johnels, J.A. (2024) Speech sound error patterns may signal language disorder in Swedish preschool children with autism. International Journal of Language & Communication Disorders, 59, 2516–2527. https://doi.org/10.1111/1460-6984.13099Please be aware that the views expressed are those of the guests and not the RCSLT.

Join Sue for an upcoming Live Virtual Workshop where you will learn from Sue practical tips & strategies to make a difference. ✅ Emotional Regulation: Teach children to recognize and manage their emotions daily. ✅ Device Dependency: Screens prevent kids from learning to regulate emotions naturally. ✅ Developmental Gap: Kids with autism/ADHD are three years behind developmentally. ✅ Replace Behavior: Behavior serves a purpose; you can only replace it. ✅ Meltdown Stages: Understand buildup, survival, and meltdown/shutdown phases to intervene. ✅ Executive Function: Emotional control is a muscle requiring consistent practice. ✅ Whole-Class Approach: Teach emotional regulation to all children, not just struggling ones. Read more about this podcast in the show notes found via the link below suelarkey.com.au/teaching-emotional-regulation-children Join the Facebook group specifically for this podcast www.facebook.com/groups/suelarkeypodcastcommunity/ Join my Neurodiversity Network suelarkey.com.au/neurodiversity-network/ Follow my Instagram account for regular tips www.instagram.com/sue.larkey/ To learn more about teaching or understanding ASD, please visit my website below. elearning.suelarkey.com.au

Good morning. An odd group gathered this weekend at the Hay Festival for a simple but moving ceremony. Local authority officials joined storytellers and puppeteers beside the River Wye to launch a charter declaring that the river has rights – rights to perform its natural functions and be free from pollution. It's the latest expression of a global movement demanding that the law sees ecosystems as living entities rather than human property. I love walking the Wye. It winds 150 miles along the Wales-England border through lush pastures and rocky gorges. Yet, there are concerns that some industrial farming practices while not necessarily illegal are polluting the river and that species like salmon and native crayfish that depend on it are disappearing. The charter recognises an ecologist as the river's official representative at rive r management meetings. The Wye can't tell us what it wants, so she's charged to present what the river needs to flourish, setting aside human interests and preferences. This legal arrangement gives form to something we've long felt but struggled to enact. The poet William Wordsworth, who celebrated the Wye, sensed that people and rivers belong to something more fundamental, "more deeply interfused" as he writes. But I think the thirteenth century Japanese Buddhist teacher Dōgen Zenji saw most clearly what that perception really means. Dōgen knew that a river can be seen as a resource, a place of inspiration, and presumably it's something quite different to the fish. But all these perceptions fall short of a more elusive reality. As Dōgen writes, “It's not only that there is water in the world, but there's a world in water.” We typically live as though we were separate — each of us the centre of our own world, bending what surrounds us to our interests. Buddhism calls this the core delusion and the source of our suffering. So our response to nature is also a call to look at ourselves more deeply, asking not just whether a river is alive, but what it means for us to be alive, within a vast universe on which we entirely depend. The Wye is one of the most loved rivers in Britain, and one of the most damaged. The charter gives it rights. But the rights of nature return to us as duties of attention, restraint, and repair — not just in beautiful places, but at every point where our lives touch the world that sustains them.

In this episode, we talk about May's adventures which include travels to GA, SC, NC, TN, VA, OH, and IN. Highlights were MANY hotel tours, COSI Science Museum, United State Air Force Museum, Thomas Bus Tour, Gem Mining, Waterfall, and time with Family & friends. The IWMF conference for Sandy's conference went well and provided some hope for future treatments. We also talk about Bryce's improvement and growth with social interactions. He has also discovered a new interest in fishing. Lastly, we talk about the discovery of two curves in Bryce's spine caused by Scoliosis. We will be monitoring his growth with x-rays with the expectation that he will need a back brace at some point to prevent the need for surgery as he grows through puberty. You can reach out directly to us if you want to purchase a signed edition of our book, "PARENTING AUTISM: The Early Years." We have several Author copies available.Bryce is a funny, mechanical, HAPPY little guy who was diagnosed with autism at age two and is now twelve years old. His pure joy makes this world a much better place!We are humbled and honored to follow our calling and be Autism Ambassadors while helping others understand our world a little more than they did before listening to the podcast. We also feel called to bring light to a community that has experienced dark days after the "diagnosis". (Luke 1:79)You can follow us on our Parenting Autism YouTube Channel (Parenting Autism Show) and our Facebook & Instagram pages to see stories, pictures, and videos of our autism journey. You can also contact us through Facebook, Instagram, or by email: parentingautism@att.net.NOTE: Most of our Social Media content is on our YouTube channel @parentingautismshow. Please subscribe and follow our adventures! Support the show

Join Sue for an upcoming Live Virtual Workshop where you will learn from Sue practical tips & strategies to make a difference. In this episode, we will discuss: ✅ Medication Discovery: Different medications affect each child uniquely and require trial. ✅ Documentation Practice: Keep diary or voice memos tracking behavior and dosage changes. ✅ Team Approach: Collaborate with parents, teachers, and doctors for best outcomes. ✅ School Impact: Right medication enables children to concentrate and access therapies. ✅ Parental Alignment: Partners may need education to understand medication benefits clearly. ✅ Child's Voice: Listen to child's experiences and observations about medication effects. ✅ Transition Monitoring: Growth, hormones, and school changes require ongoing medication adjustment. Read more about this podcast in the show notes found via the link below suelarkey.com.au/neurodiverse-and-medication-strategies Join the Facebook group specifically for this podcast www.facebook.com/groups/suelarkeypodcastcommunity/ Join my Neurodiversity Network suelarkey.com.au/neurodiversity-network/ Follow my Instagram account for regular tips www.instagram.com/sue.larkey/ To learn more about teaching or understanding ASD, please visit my website below. elearning.suelarkey.com.au

Becca Lory Hector, an autistic self-advocate, has the lived experience of moving through different environments that afford different access to nature, and natural activities. She, Barry, and Dave discuss the benefits of immersion in nature and nature activities and contrast those benefits with the challenges of limited access. They also discuss the importance of awareness and modifying life routines with sensitivity to seasonal changes.Learn more on our websiteSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Two years after receiving my AuDHD diagnosis (a combination of autism spectrum disorder (ASD-1) and ADHD I'm revisiting what it is to be AuDHD with radical honesty and a lavalier microphone from my bed, because BURNOUT. In this episode I'm opening up about what burnout looks like in real time, and how I made a decision that showing up imperfectly will better reset my nervous system than not showing up at all. I talk a little bit about the latest research on AuDHD and how the world is moving closer to recognizing it for the third neurotype that I truly believe it to be. Join the June Summer Reading Book Club Hosted by Jen! Click to Join the Community and you can get the book Tiny Experiments here at 20% off!  Sources For This Episode:  What Is AuDHD? - WebMD The Rise Of AuDHD - The Sachs Center  My original AuDHD Diagnosis Episode #44 "From ADHD to AuDHD: My Autism Diagnosis"  A Whole Lot Of Things That Support YOU & This Podcast!  We Are A Lot Community + Podcast (Patreon) — $24.99/month: Full community access on Circle plus ad-free episodes, bonus episodes, and video episodes on Patreon. We Are A Lot Community — $17/month: 24/7 support hub with daily body doubling sessions and weekly meetings with Jen & other members and over ten sections of guided online ADHD/AuDHD help hubs made by Jen. (Use code WELCOME7 at checkout and get $7 off of your first month, cancel anytime easily, no sales pressure) Body Doubling Only — $7.99 month: Daily body doubling sessions with Jen & other members. (Use code WELCOME3 at checkout and get $3 off of your first month, cancel anytime easily, no sales pressure) Shop Jen's Favorite ADHD Supports (with Discounts) Brain.fm — A Focus Tool I Use Every Day I listen while I work and I can feel my brain lock in. It's not AI, or binaural beats. Brain.fm is science-backed sound made by musicians and scientists for ADHD brains. I want you to try it for 30 days free, with my link! Little Ouchies - Self Regulation Stim Tools! I LOVE my Little Ouchies. I use them daily when I'm working, writing, thinking, and it really helps me to stay in the moment by regulating my nervous system. I tend to ruminate with Imposter Syndrome when I'm in deep work. It's also just fun and feels good, so even watching TV or other mindless activities are made more stimulating by rolling one in my hands. Get 10% off with this link and use ALOT10 at checkout!  Bookshop.org — Books I Recommend I love Bookshop.org because every purchase supports your local independent bookstore, not Amazon, while still shipping directly to you. I've curated book lists on ADHD/AuDHD and mental health, and you can get 20% off everything when you shop using my link. Hugimals — Weighted Comfort for Kids & Adults I own Hugimals, give them as gifts, and love that they're made by a neurodivergent founder who understands nervous system needs. These weighted stuffed animals and pillows help with anxiety and overwhelm, and you can get 15% off anytime using my link and code JENKIRKMAN (it never expires). The Time Timer - a Cute Visual Time Tool! I use my Time Timer every single day to help me visualize time during work blocks, and to gamify chores. There's no discount, but when you use my link I earn a percentage that goes directly into supporting this podcast. The Big A## Calendar I have the Big A## wall calendar that maps out the entire year and the Big A## personal planner with 365 days in one view, dry erase markers, color coded labels. With my unique link you can get 10% off of your order. Appointed — Planners, Notebooks & Desk Goods Appointed notebooks are my go-to for my spiral notebooks, day planners, calendars and Le Pen pens for list-making, journaling, and planning. Save 15% off with my link and code JENKIRKMAN. Bearaby - Weighted Blankets, Warmables, Stress Pillows I LOVE my Bearaby cooling weighted blankets, the weighted and warmable lap lounger, I need their products daily to regulate and relax. Their products are built to calm the body down and support a. natural sleep cycle.  UnHide - Weighted Faux Fur Blankets, Pillows, Plush Home Goods I LOVE my UnHide faux fur weighted blankets, my squish pillows and my backrest that is always on my bed for my sitting up in bed working days. Get 20% off everything with my link and JENNIFER at checkout.  

Dr. Deb Muth 00:04What if the future of healing isn’t about replacing cells, but about teaching your body how to heal itself again? We keep hearing the words stem cells and exoomes thrown around like they’re interchangeable, but they’re not. One is regulated, controversial, and often misunderstood. The other is rapidly emerging as one of the most exciting communication systems in human biology. Dr. Deb Muth 00:33And here’s the real question no one’s asking. Are we actually regenerating tissue or are we just stimulating the body to remember how it used to heal? Tired of being told your labs are normal, but you still feel terrible? At Serenity Healthcare Center, we don’t chase symptoms. We find the root cause. hormones, gut health, autoimmune conditions, chronic fatigue, brain fog. Dr. Deb Muth 01:02We use cuttingedge functional and regenerative medicine to get you real answers and a real path forward. This isn’t your average doctor’s office. This is medicine the way it was meant to be practiced. You deserve to feel like yourself again. Visit serenityhealthcarecenter.com to book your appointment today. Let us help you heal from the inside out. Dr. Deb Muth 01:28Welcome back to Let’s Talk Wellness Now. I’m Dr. Deb, your host. And if you’ve been following regenerative medicine, you’ve probably noticed the confusion. Patients are asking me every week, are exoomes stem cells? Are stem cells legal in the United States? I heard the FDA is shutting down all these clinics. Can I even get this therapy? Do I have to leave the country for treatment? Today, we’re cutting through the noise. This episode is not hype. Dr. Deb Muth 01:54It’s not sales. It’s education so you can understand the science, the regulatory reality, and the clinical difference between stem cell therapy and exoome therapy. And here’s what I want you to know right up front. Yes, these therapies are being used in the United States every single day. Yes, they’re being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 02:22Some are being used in FDA registered clinical trials. Some are being used in observational studies and some are being used in clinical practice under physician discretion. The landscape is nuanced and you deserve to understand it. So, grab your cup of coffee or tea and settle in for a deep dive into the most understood therapies in regenerative medicine. Dr. Deb Muth 02:43what they actually are, how they work, the regulatory landscape, and how they might support your body’s natural healing capacity. Let’s talk wellness now. So, let me start by asking you something. When you hear the word stem cell, what do you picture? Most people imagine damaged tissues magically regenerating or a torn meniscus growing back, cartilage reforming it into an arthritic joint or damaged brain tissue being replaced with healthy new beautiful cells. It’s a beautiful vision. Dr. Deb Muth 03:15And while it’s not quite that simple, the reality is actually more sophisticated and honestly more beautiful. Stem cells are powerful and they absolutely work, but the way they work and the mechanism by which they support healing is far more elegant and more so than most people really understand. And if you’re going to invest in regenerative therapy, you deserve to understand what you’re actually receiving. Dr. Deb Muth 03:44So, let’s start at the beginning. What are stem cells? At their core, stem cells are undifferentiated cells. That means they haven’t yet decided what they want to be when they grow up. Unlike a heart cell or a skin cell or a bone cell which have already committed to a specific function, stem cells exist in this beautiful state of potential. Dr. Deb Muth 04:05They have two remarkable abilities. First, they can self-renew. They can make copies of themselves, maintaining a reserve of these powerful cells throughout your lifetime. Second, they can differentiate under the right conditions. They can transform into specialized cell types. Bone cells, cartilage cells, nerve cells, muscle cells, even blood cells. Dr. Deb Muth 04:27This is why they’ve captured the imagination of the medical world. The potential is extraordinary. Now, there are several types of stem cells and understanding the differences matters tremendously for both understanding how they work and understanding how they’re regulated. Adult mezzenymal stem cells. We call these MSC’s are the most commonly used regenerative medicine. Dr. Deb Muth 04:54These come from bone marrow, atapost tissue, that’s fat, and other adult sources. They’re what we can call multi-potent, meaning they can become several types of cells, but not every type. A bone marrow stem cell isn’t going to become a brain cell, for instance. It has potential but it’s directed potential. Dr. Deb Muth 05:19Then we have perinatal stem cells. These come from umbilical cord blood cord tissue or something called Wharton’s jelly which is the gelatinous substance inside the umbilical cord. These cells are younger, more potent, and research by Weiss and colleagues published in stem cells back in 2006 showed that Wharton’s jelly derived MSC’s have superior proliferation and differentiation potential compared to bone marrow derived cells. Dr. Deb Muth 05:48They’re like comparing a 20-year-old athlete to a 50-year-old athlete. Both can perform, but one has more reserve capacity, more vigor, and more regenerative potential. And this isn’t this is very important because the perinatal sources umbilical cord tissue Wharton’s jelly amniotic tissue these are what many regenerative medicine clinics in the United States are using today and they’re using them because these tissues are incredibly rich in not just stem cells but growth factors cytoines and exoomes. Dr. Deb Muth 06:21Then there are embryionic stem cells. These are pur potent and they become any cell type in the body, but they’re highly regulated, ethically controversial, and honestly, they’re not being used in clinical practice in the United States outside of the very specific FDA approved research trials. Dr. Deb Muth 06:41So, when clinics talk about stem cell therapy, they’re almost never talking about embryionic stem cells. Now, here’s where it gets interesting and this is the part that changes everything about how we understand regenerative medicine. When you receive stem cell therapy, let’s say someone injects umbilical cord derived messenymal stem cells into your arthritic knee, those cells do not typically engraft or become new tissue in any permanent way. Dr. Deb Muth 07:12They don’t set up shop in your joint and start cracking out new cartilage cells for the rest of your life. So what are they actually doing then? Well, in 2011, researchers Arnold Arnold Kaplan and Dennis Korea published a landmark paper in stem cells translational medicine that fundamentally changed how we understand MSC therapy. Dr. Deb Muth 07:35They proposed that we should stop calling memal stem cells and start calling them medicinal signaling cells. Why? Well, because their primary therapeutic benefit doesn’t come from what they become. It comes from what they secrete. Think of stem cells as incredibly sophisticated biological pharmacies. When you inject them into damaged tissue, that arthritic knee, that inflamed autoimmune condition, that injured brain, that don’t just sit there passively, they sense the environment. Dr. Deb Muth 08:07They detect inflammation. They recognize the tissue damage and they understand that the immune dysregulation is present and they see that and respond. They start pumping out hundreds of bioactive molecules, growth factors that tell your cells to repair and rebuild, cytoines that modulate inflammation, chemocines that recruit your body’s own healing cells to the area. Dr. Deb Muth 08:32And these tiny membranes bound packages called extracellular vesicles, including exosomes, which we’re going to talk about extensively today as well. These secreted factors are giving instructions to your native cells. They’re saying, “Let’s reduce inflammation. Let’s modulate your immune response. Let’s promote angioenesis. Dr. Deb Muth 08:53” That’s the formation of new blood vessels, bringing nutrients and oxygen. Let’s stimulate your own resident stem cells to wake up and get to work. Reduce cell death in damaged tissue and restore normal cellular function. This is called paracrine signaling. It’s the cellto cell communication. And this is where the real therapeutic power lives. Dr. Deb Muth 09:14The stem cells themselves, many of them die within days to weeks, but the cascade of healing they trigger, the signals they send, the programs they activate in your own cells, those effects can last for months or even years. Now, this understanding is crucial because it explains why both stem cell therapy and exoo therapy can be effective. Dr. Deb Muth 09:38The stem cells are powerful not because they become new tissue but because of the signals they send and exoomes are those signals isolated and concentrated. The biggest misconception in regenerative medicine is that stem cells replace tissue and in reality they coach healing more than they become healing. They’re biological educators teaching your body to remember how it used to heal before chronic inflammation, toxicity, and disease turned off all those programs. Dr. Deb Muth 10:12So if stem cells don’t exactly end graft and become the new tissue, if their power is in their signaling and then next logical question is why do we need the cells at all? Well, if we could isolate the messengers themselves, what if we could deliver just the communication systems without any of the complexity of the living cells? Well, that’s exactly what exosomes are. Dr. Deb Muth 10:38And they represent the cutting edge of regenerative medicine. So, let me paint you a picture of how cells actually communicate. Because for most medical history, we had it wrong. For decades, textbooks taught us that cells talk to each other in two basic ways. through direct contact like shaking hands or releasing signaling molecules that floated through the extracellular space like messages in bottles, simple chemical messages. Dr. Deb Muth 11:09But in the 1980s and 90s, researchers started discovering something far more sophisticated. cells were releasing these tiny membrane bound packages like a biological FedEx envelope kind of you know it was filled with complex specific cargo and these packages could travel through the blood cross the barriers that normally keep things out like bloodb brain barrier and deliver their contents to distant cells with remarkable precision. Dr. Deb Muth 11:38These are called extracellular vesicles. And exoomes are one of the most therapeutic important types. So what exactly are exosomes? Well, they’re nanosized vesicles, typically 30 to 150 nanome in diameter. To put that into perspective, a human hair is about 100,000 nanometers wide. These are incredible and most impossibly tiny. Dr. Deb Muth 12:09They’re released by virtually all cells in the body, but the most therapeutically interesting exoomes come from mezenymal stem cells. And those medicinal signaling cells we just discussed. And according to a landmark review of Raposo and Stervogal, they published in the journal of cell biology in 2013, exoomes are not cellular debris. They’re not waste products. Dr. Deb Muth 12:35They are precisely engineered communication vesicles or vehicles. Think of them as sophisticated delivery systems carefully packed, carefully labeled, and sent to specific destinations. very specific instructions. Inside each of these exoomes, you’ll find an incredibly sophisticated payload. They are microRNAs. These are small RNA molecules that can literally turn genes off or on in the recipient cells. Dr. Deb Muth 13:06They can tell a cell to start making more collagen, to reduce inflammatory proteins, to activate repair programs that have been shut down by chronic disease for a very long time. There are messenger RNAs, actual templates for protein production. And exoome can deliver these instructions for making healing proteins. There are proteins themselves, growth factors, cytoines, enzymes, all the molecular tools a cell needs to heal. Dr. Deb Muth 13:34And there are lipids, specialized fats that help the exoome membrane fuse with targeted cells, delivering the cargo inside. When an exoome reaches its target cell, it can either fuse the cell membrane and deliver its contents directly inside like a Trojan horse, or it can bind to surface receptors and trigger signaling cascades, setting off a chain reaction of healing responses. Dr. Deb Muth 14:01Either way, it’s delivering very specific targeted instruction. And here’s what makes this so powerful. Those instructions are tailored to what this recipient cell actually needs. So, let me give you some concrete examples of what the research actually shows because this is where it really gets exciting. When researchers inject MSC derived exoomes into hearts that had experienced eskeeia, reprofusion, injury, that’s damaged blood flow being cut off and then being restored. Dr. Deb Muth 14:36Kind of like what happens during a heart attack. Something remarkable happened. A study by Lei and colleagues published in stem cell research in 2010 showed that exoomes significantly reduced the size of the damaged area, reduced inflammatory cytoines that drive tissue destruction and promoted tissue repair signaling. The exoomes were telling the heart cells stop the inflammatory cascade, activate your survival programs and repair the damage. Dr. Deb Muth 15:06In cartilage research, tow and colleagues published work in biioaterials in 2017 showing that exosomes derived from MSC’s could promote cartilage regeneration in osteoarthritis models. And the exoomes carried specific microRNAs that told condondroytes cartilage cells to proliferate and make more extracellular matrix, the structural framework of healthy cartilage. Dr. Deb Muth 15:30for autoimmune conditions. Research by Blazic and colleagues in Frontiers in Immunology in 2014 demonstrated that MSC derived exoomes could shift immune cell behavior from pro pro-inflammatory to regulatory. They could take an overactive self-attacking immune system and restore balance and promote tolerance. And perhaps most exciting brain research, a study by Zinn and colleagues published in the journal of extracellular vesicles in 2013 showed that MSC derived exoomes could cross the bloodb brain barrier. Dr. Deb Muth 16:07That protective shield around your brain that normally keep things out and promote neurological recovery in stroke models. They reduced brain inflammation, promoted neuroplasticity, supported the formation of neural connections, and for mitochondrial dysfunction, which underlies so many chronic conditions, Morrison and colleagues published research and scientific reports in 2017 showing that MSC derived exoomes can actually deliver functional mitochondria or mitochondrial components to damaged cells. They’re not Dr. Deb Muth 16:40just sending instructions, they’re sending spare parts. They’re restoring the cellular powerhouses to produce energy. So why are exoomes fundamentally different from stem cells? Well, exoomes contain no living cells. They can’t replicate. They can’t end graph. And they have virtually no risk of immune rejection or tumor formation. Dr. Deb Muth 17:03Concerns that exist elevate rarely with cellular therapies. They’re essentially biological software updates for your cells. As Fineian Pitiger wrote in their seinal review in stem cells in 2017, MSC derived exoomes represent the active ingredient of stem cell therapy delivered in a cellfree format. That’s the key insight in the in the therapeutic benefit of stem cells and it comes from what they excrete. Dr. Deb Muth 17:33Then exoomes are the secretion isolated, concentrated, and standardized. From a practical clinical standpoint, exoomes offer several compelling advantages. First, consistency. Because exoomes can be isolated, characterized, and standardized, each dose can be remarkably consistent. With living stem cells, there’s variability based on donor age, health status, processing methods, and one batch may be robust, but another might be weaker. Dr. Deb Muth 18:05With exoomes, you can measure the content, measure the potency, and ensure the quality control. Second is storage. Exoomes can be liophalized. They can be freeze-dried and stored at room temperature or refrigerated for extended periods. Stem cells require cryopreserv preservation, careful freezing, careful thawing. They’re fragile. Dr. Deb Muth 18:31Exoomes are remarkably stable. And third, their safety profile. Without living cells, the risk of adverse imunological reactions is dramatically lower. You’re not introducing foreign cells that your immune system might recognize and attack. You’re introducing molecular messages. Fourth is scalability. You can harvest millions, even billions of exoomes from stem cell cultures without ever injecting the cells themselves. Dr. Deb Muth 19:01And you can produce large quantities, standardize them, and make them available to patients. Now, there is a caution here in doing this. The scalability can produce rogue cells, and we want to be cautious of that. So, here’s what I need you to understand. Exoomes don’t force healing. They remind the body how healing works. Dr. Deb Muth 19:24They’re not replacing damaged cells. They’re re-educating the cells you already have. They’re turning back time on the biological programs that got turned off by inflammation, toxicity, trauma, time, and chronic disease. Your body knows how to heal. It’s done its entire life. Every cut that closed, every bone that mended, every infection you fought off, your body orchestrated that healing. Dr. Deb Muth 19:51The problem is that chronic disease, chronic inflammation, toxic exposures, poor nutrition, stress, all of these things disrupt the communication networks that coordinate healing. And exoomes restore that communication. They’re like rebooting a computer that’s frozen. They reset the system and remind it how it’s supposed to function. All right. Dr. Deb Muth 20:14So, this would not be complete if we didn’t talk about regulation because this is where a lot of confusion exists. And I want you to be given a real picture. Not fear-mongering, not pretending. There aren’t regulatory considerations, but the actual practical reality of how regenerative medicine is practiced in the United States today. Dr. Deb Muth 20:38Here’s what you need to understand. The FDA regulates these therapies and they have specific frameworks, but there’s important nuances between regulatory text enforcement priorities and actual clinical practice. And there are also state level regulations that provide additional pathways. The FDA regulates human cells, tissues, and cellular and tissue based products. Dr. Deb Muth 21:05We call them HCT/PPS under two main pathways. Section 361 products are those that meet specific criteria. They’re minimally manipulated, intended for homologous use, meaning these tissues perform the same basic function in the recipient as it did in the donor. They’re not combined with non-tissue components and they’re either autotogus, meaning they come from your own tissue, or they have had minimal systemic effect. Dr. Deb Muth 21:38An example of a clear 361 procedure, your doctor harvests your own bone marrow, we call this PRP, performs minimally processing to or uh perform Yeah. performs minimal processing to concentrate the stem cells through a centriuge and injects it into your arthritic knee the same day. That’s autogus same day but minimally manipulated. Dr. Deb Muth 22:04This is unquestionably legal and is being done in regenerative medicine clinics across the country every single day. So there’s section 351 where products are those that don’t meet all the section 361 criteria. They’re classified as drugs or biologic products and they require FDA approval through clinical trials. Dr. Deb Muth 22:27Now here’s where this gets more nuanced. There are regenerative medicine clinics across the United States using stem cell and exoome therapies in different contexts. First FDA registered clinical trials. These are formal research studies with investigational new drug applications. Patients enroll in trials. They sign informed consents. Dr. Deb Muth 22:48They receive therapies as part of their structured research protocols. And this is completely legal and represents the gold standard for gathering evidence. Second is observational studies and registry programs. Many clinics are collecting systemic data on patient outcomes using these therapies even outside the FDA trials. Dr. Deb Muth 23:12They’re documenting results, tracking safety, and contributing to the growing body of clinical evidence. Third, there’s clinical practice under physician discretion. There are physicians using these therapies based on their own clinical judgment informed consent from patients and their interpretation of the regulatory framework particularly around minimal manipulation and homologous use. Dr. Deb Muth 23:34Now there are also state regulations that provide additional legal frameworks. So, for example, Florida has enacted the Right to Try Act and specific regenerative medicine legislation that allows physicians to offer certain stem cell therapies under the state oversight. Utah has passed similar legislation creating pathways for regenerative medicine products. Dr. Deb Muth 23:57And these state laws recognize that patients should have access to potentially beneficial therapies, particularly when used by trained physicians with appropriate informed consent. The regulatory question often centers around are these products minimally manipulated. Some products clearly are not. They’ve been cultured. Dr. Deb Muth 24:20They’ve been expanded in laboratories and those require FDA approval that they don’t have. The FDA has appropriately shut down clinics using those products. But there are other products that undergo processing that many physicians and manufacturers argue constitutes minimal manipulation. And these tissues are cleared, potentially fragmented or particulated to make them more suitable for injection, preserved using methods like cryopreservation or liophalization and packaged. Dr. Deb Muth 24:54But the cells are not cultured or expanded in the laboratory. The FDA has issued guidance suggesting that many of these processing steps constitute more than manipul minimal manipulation. But many physicians, particularly those who specialized in regenerative medicine for years, disagree with that interpretation and they believe that the processing qualifies as minimal manipulation and that the product should fall under section 361 when used for homologous purposes. Dr. Deb Muth 25:24Is there regulatory debate? Absolutely. The FDA and some clinicians have different interpretations of what constitutes minimal manipulation. But here’s the practical reality. There are hundreds of well-trained, bore certified physicians across the United States offering these therapies every single day. Dr. Deb Muth 25:42They’re doing so based on their understanding of the regulations, their clinical experience, their commitment to patient safety, and their belief that these therapies can help people who have exhausted conventional options. The FDA’s enforcement priorities have focused primarily on the most problematic cases. Clin clinics making blatant disease cure claims, products with documented safety issues, clear cases of cellular expansion and culture, or clinics operating with no medical oversight. Dr. Deb Muth 26:15Reputable regenerative medicine physicians are using products from companies that provide comprehensive documentation of their processing methods. third-party sterility testing, certificates of analysis showing bioactive content, and quality control measures that meet or exceed industry standards. Now, let me be very clear about something. Dr. Deb Muth 26:36Quality matters enormously. Not all stem cells and exoome products are created equal. Research by Burger and colleagues published in the Orthopedic Journal of Sports Medicine in 2021 analyzed 12 commercially available stem cell products and found that many contained zero viable cells, high levels of bacteria, endotoxins and inconsistent growth factor concentrations. Dr. Deb Muth 27:01This is why the company providing these biologic matters tremendously. You want products from manufacturers who provide transport documentation in sourcing and processing. Conduct third-party testing and sterility and potency. Offer certificates of analysis for each batch. Use standardized validated processing protocols. Dr. Deb Muth 27:24Have quality control measures that ensure consistency and don’t make outrageous cure claims or promise. The best regenerative medicine physician carefully vet their suppliers. They don’t use products from companies making unrealistic promises. They use products from manufacturers who are transparent, scientifically rigorous, and committed to quality. Dr. Deb Muth 27:46Now, you specifically ask about homologous use and collagen defects. So, let me address this directly for you. Under the FDA guidance, homologous use means the tissue performs the same basic function in the recipient as in the donor. So for connective tissue, tendons, ligaments, cartilage, fascia, all of that which are collagenrich structures using MSC’s or their derivatives could be considered homologous use. Dr. Deb Muth 28:17MSC’s in their native environment provide structural support to produce extracellular matrix including collagen. Using them to support healing in damaged collagen rich tissues like arthritic joints, torn tendons or degenerative ligaments is arguably the same basic function. So using exoomes derived from MSC’s to support collagen synthesis reduce inflammation and promote tissue healing in the same structures. Dr. Deb Muth 28:46Many practitioners argue this also qualifies as homologous use because you’re supporting the structure and function that MSC’s would naturally support. So here’s the bottom line on the regulatory reality. Regenerative medicine is available in the United States. It’s being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 29:11Some therapies are offered in FDA registered clinics and some are offered in observational studies. Some are offered in clinical practice under physician discretion, informed consent, and careful attention to safety. The regulatory landscape is evolving. There are ongoing discussions both federally and state levels about creating clearer pathways for these therapies. Dr. Deb Muth 29:32So, if you choose to go down this road, you want to work with physicians who understand the regulations, who use quality products from reputable manufacturers with rigorous testing and documentation, who are transparent about what they’re using and why, who discuss the current regulatory landscape honestly with you, and who prioritize your safety and truly informed consent above all else. Dr. Deb Muth 29:55This is not a lawless wild wild west. But it is also not as simple as everything is legal and unavailable. It’s a nuanced landscape that requires ethical knowledge. And these practitioners that have this knowledge have got to provide informed patients who understand both the potential benefits and the current regulatory context. Dr. Deb Muth 30:17So let’s have some fun here. Let’s talk about what really matters to you that are listening and that’s what conditions are being supported with these therapies. What does the research show and what are clinicians seeing in actual practice with patients? Because here’s what’s really important. We have both published research evidence and extensive clinical experience. Dr. Deb Muth 30:38And when the two align, that’s when we can feel confident and comfortable about using these approaches. So, let’s start where we have the most substantial evidence. joint health and muscularkeeletal conditions. For arthritis, we have good data. A systemic review by Tan and colleagues published in arthritis research and therapy in 2021 analyzed 20 randomized controlled trials in MSC therapy for knee osteoarthritis. Dr. Deb Muth 31:05They found significant improvements in pain and function particularly in mild to moderate disease. What’s really interesting is when researchers start analyzing whether it was the cells themselves or their secreted factors doing the work. They found that exoomeenriched preparations showed similar benefits to whole cell therapy. Dr. Deb Muth 31:26Now towen colleagues in the biioaterials paper from 2017 demonstrated that MSC derived exoomes could promote cartilage matrix synthesize and reduce inflammation markers. The exoomes carried microarnas that told cartilage cells to make more collagen and proteoglycans, the building blocks of healthy cartilage. Dr. Deb Muth 31:49In clinical practice, physicians are seeing patients with knee, hip, shoulder, and spinal arthritis, experiencing reduced pain, improved function, better motility, and in some cases, measurable improvements in their tissue. I want to share a story here with you because back in 2006, my husband was injured at work. Some of you might have heard me tell this story before. Dr. Deb Muth 32:11Um, he broke two discs in his back and underwent surgery very early on when we started using stem cells. They had put cages and plates in and they used MSC’s to put inside the cage to create a hardened bone so that he could have a fusion and hopefully not have any pain. At the time, what the physician didn’t realize or mistakenly did was he did not put any human bone mixed with these dead cadaavver bone MSC’s. Dr. Deb Muth 32:42And so the MSC’s never grew. They didn’t have anything to grow by. So the plates and the screws just kind of went back and forth for six months before he could see another physician that would look at him differently and understand what actually happened. That was very early on. Today we know so much more than we did before. Dr. Deb Muth 33:01Fast forward to 2014 when my husband was having problems and he couldn’t feel his legs, he couldn’t feel his feet. We decided to undergo uh exoo and stem cell therapy again and we saw a physician in Florida who harvested cells from his bone marrow and his blood and his fat and mixed that all together and then put that back into the back. Dr. Deb Muth 33:27and he had tremendous benefit from it. So, I tell this story because I want you to see the trajectory of how long this has been going on that we’ve been using this and we’re learning as we’re going and things are changing rapidly in this in this world. And so, what we know today and what I’m teaching you today may very well change in a month or six months or a year from now, but we have the foundation at least to understand what is helpful, what is not right now. Dr. Deb Muth 33:54But just be aware that if you’re embarking on exoome or stem cell therapy or MSC’s that you understand that this terrain is going to change. So back to my conversation about what other things can we treat? Well, we can treat tendon and ligament injuries, chronic tennis elbow, Achilles tendonopathy, rotator cuff tears, chronic planter fasciitis. Dr. Deb Muth 34:17These were researched by PA and colleagues in the American Journal of Sports Medicine in 2017 and it showed that bone marrow concentrate injections resulted in improved pain and function compared to steroid injections. Now this mechanism appears to be enhanced collagen remodeling and reduced chronic inflammation. Dr. Deb Muth 34:39These are structural collagenrich tissues using MSC’s or their derivatives for structural support which makes biological sense. It’s homologous use. It’s similar. So clinically we’re seeing athletes, active adults and people with chronic pain who failed physically um failed physical therapy, failed conservative treatments finding relief in this functional uh improvement in this functional world that we live in today. Dr. Deb Muth 35:07So, I want to be clear about what we’re doing here for joint and muscularkeeletal issues. We’re not growing completely new cartilage from scratch or severely destroyed joints. We’re not magically regenerating tissues that’s been gone for decades. That’s not possible here. What you’re doing when you’re using MSSE’s and exoomes is supporting the body’s natural ability to repair, reducing inflam inflammation and damage, and we’re driving progressive degeneration uh or we’re stopping the progressive degeneration. By reducing the Dr. Deb Muth 35:41inflammatory damage, we’re stimulating resonant stem cells that have been dormant. We’re improving blood flow and uh uh oxygen to the tissues like cartilage and tendons. and we’re organizing the body to start creating its own quality collagen as it heals. So, it’s a regenerative support, not a tissue replacement. Dr. Deb Muth 36:07But for many people, this support is lifechanging. So, let’s talk about autoimmune disorders now because this is one of the most exciting and unrecognized applications. autoimmune conditions like rheumatoid arthritis, lupus, MS, Crohn’s disease, ulcerative colitis, Hashimoto’s, they all involve the immune system and the immune system is deregulated. Dr. Deb Muth 36:30And so basically your immune system is seeing this tissue as foreign and it’s attacking it. These MSC’s and their exoomes have profound immune modulatory properties. They don’t suppress the immune system like steroids or imunosuppressive drugs. They modulate it helping to restore balance. So for rheumatoid arthritis, research by Weang and colleagues in stem cells translational medicine in 2016 showed that MSC derived exoomes could shift the balance of immune cells, reducing pro-inflammatory TH7 cells that drive joint disruption uh and increase Dr. Deb Muth 37:08regulatory TE-C cells that maintain immune tolerance. So for MS, a clinical trial by Kasus and colleagues published in archives of neurology back in 2010 evaluated autotogus MSC therapy and MS patients and they found evidence of reduced disease activity, improved neurological function and decreased inflammatory uh lesions on MRI scans. Dr. Deb Muth 37:34The proposed mechanism is MSC’s and their exoomes reduce inflammatory cytoine production promote regulatory imu immune populations support remination of damaged nerves that is rebuilding the protective coating around the nerve fibers and it reduces bloodb brain barrier permeability which prevents immune cells from attacking their brain and spinal cord. Dr. Deb Muth 38:02And so for inflammatory bowel disease, the research by Barnholm uh sorry Barnhorn and colleagues in gut in 2020 showed that MS cell MSC derived extracellular vesicles could support mucosal healing and reduce inflammation in the gut lining. They appeared to restore intestinal barrier function, healing that leaky gut and modulating local immune responses. Dr. Deb Muth 38:30So in clinical practice, physicians are seeing patients with autoimmune conditions, experiencing reduced disease flares, decreasing the need for imunosuppressive medications, improving energy and quality of life, and in some cases extending periods of remission. But here’s what I want you to understand. Dr. Deb Muth 38:52When you see these therapies for autoimmune conditions, we are supporting immune regulation and reducing inflammatory damage. We are not treating or curing the disease in a conventional sense. These therapies work best as part of a comprehensive functional medicine approach that also addresses gut health because 70% of your immune system lives in your gut and environmental triggers like mold, heavy metals, chemical toxins that can drive autoimmune responses, chronic infections that can trigger immune disregulation, stress and nervous system imbalance. And Dr. Deb Muth 39:29these nutritional deficiencies are necessary to help improve the immune function. So regenerative therapy without addressing root causes is like bailing water out of your boat without plugging the hole. You might get temporary relief, but the underlying problem still remains. So let’s talk about neurological conditions. Dr. Deb Muth 39:52And this is where the science gets truly fascinating. for traumatic brain injury and concussion. Research by Zang and colleagues in the Journal of Neurot Trauma in 2015 showed that MSC derived exoomes could reduce brain inflammation, promote neuroplasticity, that’s the brain’s ability to rewire itself and improve cognitive outcomes in animal models. Dr. Deb Muth 40:17The exoomes crossed the bloodb brain barrier, delivered neuroprotective proteins and microRNAs. They reduced inflammation, supported mitochondrial function in injured neurons and promoted both new blood vessels from new blood formation and neurogenesis and the birth of new neurons occurred. Neurological recovery requires a multi-systematic approach. Dr. Deb Muth 40:42Exoomes may support neural repair, but they work best combined with hormone optimization, growth hormone, testosterone, thyroid, pregnnolone, mitochondrial support compounds like NAD, CoQ10, PQQ, carnitine, all of those things that we use traditionally in functional medicine. Now for stroke recovery, there was research by Zinn and colleagues in the journal of extracellular vesicles that showed MSC derived exoomes reduced the size of brain damage and improved neurological recovery in animal models. There was a Dr. Deb Muth 41:19Parkinson’s disease study done by Kimoji and colleagues in the movement disorders in 2018 that suggested that MSSE derived exoomes could support dopamineergic neuron survival and those are the cells that die in Parkinson’s and it can help to reduce neuroinflammation. Clinically, physicians are seeing improvements in patients with postconussion syndrome, chronic traumatic brain injury, early stage cognitive decline, and other neurodeenerative conditions. Dr. Deb Muth 41:52These are not cures, but meaningful improvements in cognitive function, mood, energy, and quality of life. Now, let’s talk about autism spectrum disorder very carefully here because this is a very sensitive but very important topic for families. There have been several clinical trials that have explored MSC therapy for autism. Dr. Deb Muth 42:16Liv and colleagues published research in stem cell translational medicine in 2013 showing improvements in social interaction, communication, and behavioral symptoms in children with ASD who received cord blood MSC’s. Dawson and colleagues in 2017 conducted randomized trial autotogus cord blood infusion and found modest improvements in social communication particularly in children with higher baseline immune dysregulation. Dr. Deb Muth 42:47The proposed mechanisms for modulation of neuroinflammation support the mitochondrial function because many children with autism show evidence of mitochondrial dysfunction, reduction of oxidative stress, improvement in gut brain access dysfunction and modulation of immune dysregulation. In clinical practice, some physicians are seeing improvements in some children, better eye contact, increased language development, reduced sensory sensitivities, improved social engagement, but responses vary significantly, and we cannot predict which children will benefit most. So for Dr. Deb Muth 43:26families considering regenerative approaches for autism, these therapies are supporting the body’s healing mechanisms, reducing neuroinflammation, supporting cellular energy production, modulating immune function. These should only be considered as part of a comprehensive biomedical approach that includes dietary interventions to address food sensitivities, support gut health, environmental toxin removal, particularly heavy metals and chemical exposures, gut healing protocols with targeted probiotics and nutrients, Dr. Deb Muth 44:00metabolic testing and targeted supplementation, and evidence-based on behavioral and developmental therapies. These therapies should only be pursued with practitioners who are honest about what we know and what we don’t know and who follow rigorous safety protocols who never promise cures and who view regenerative medicine as a tool in the comprehensive healing strategy, not a standalone miracle. Dr. Deb Muth 44:26Not only that, these therapies will most likely need to be given several times over the course of this person’s lifetime, possibly even on an annual basis. And this is really important because it is not a oneandone. It is not a one-sizefits-all, and it needs to be looked at as a long-term option for working with autism. So, since we’re looking at stem cells versus exoomes, living cells, with stem cell therapy, you’re receiving living cells that can survive in your body for days to weeks. Dr. Deb Muth 45:02With exoome therapy, there are no living cells, just biological messages they would have sent. So, replication stem cells can potentially replicate. Although therapeutically this happens minimally, exoomes cannot replicate. They deliver the cargo and then they are cleared by your body. With stem cells, it’s primarily paracrine signaling. Dr. Deb Muth 45:28They’re coaching your cells to heal. With exoomes, it’s pure signaling, pure reprogramming your cells without any cellular component. Stem cells as we talked about can be autotogus from your own bone fat, blood or um bone marrow or allergenic from umbilical cord tissue or Wharton’s jelly. Dr. Deb Muth 45:50Exoomes are typically derived from cultured MSC’s often from umbilical cord or bone marrow sources and both can be given by local injection for targeted treatment of joints and tissues and exoomes can be given intravenously for whole body systemic support. both have um low immun immunogicity. I can’t say that word today. Dr. Deb Muth 46:17But exoomes have even lower risk since they contain no cellular material. Now, it’s absolutely critical for you to understand that there are massive quality differences. We’ve talked about this earlier. I want you to be very aware of this and have a conversation with any of the practitioners that you’re considering undergoing this treatment with. Dr. Deb Muth 46:37Here is where it matters more than anything when you’re considering regenerative medicine, the quality of the products and the expertise of the practitioner. Because the reality is not all regenerative medicine products are created equal. We all know that when we take different supplements and not all practitioners understand these therapies at the same depth. Dr. Deb Muth 46:58You want to look for practitioners that are board certified or have some kind of specialized regenerative medicine training. You want to know their clinical experience. How much have they done these procedures? How long have they done this? You want honest communication about the evidence and the limitations in this. Dr. Deb Muth 47:17You want a comprehensive functional medicine approach to go along with these therapies. And you want somebody that’s transparent about their informed consent and their regulatory status. If you have people that are uh claiming that they can cure disease or giving you guarantees, that is not that is not a good practitioner to work with. Dr. Deb Muth 47:37If you have high pressure sales tactics, you need to decide today limited supply for a week. These are marketing manipulations. It’s not medical care. You want to be cautious of extremely low prices because quality regenerative products are expensive to source, process, and test. and store. And if somebody’s offering stem cells or exoomes for a few hundred dollars, seriously, you need to question the quality, the safety, and where they got this from. Dr. Deb Muth 48:09So before undergoing any regenerative therapy, make sure you’re having a very, very lengthy conversation with the person and so you truly understand exactly what you’re getting, how it’s going to be delivered, and what they’re going to do. If there’s one thing I want you to take away from today is that your body has remarkable capacity to heal when given the right biological signals and the right environment. Dr. Deb Muth 48:35Stem cells and exoomes are powerful tools for providing biological signaling that can reduce inflammation, modulate immune function, support tissue repair, and restore cellular communication that’s been disrupted by chronic disease and inflammation. These therapies are available in the United States through trained physicians working in FDA registered trials, observational studies, and clinical practice, and using quality products from manufacturers with rigorous testing and quality control. Dr. Deb Muth 49:04So before you invest in regenerative medicine, do your homework. Ask detailed questions about product quality and source. Verify the products come from reputable manufacturers with certificates of analysis, third-party testing. Work with experienced practitioners. And remember, no injection, no infusion, no biologic can overcome ongoing toxic exposure, chronic stress, poor nutrition, gut dysfunction, and inadequate sleep. Dr. Deb Muth 49:34True healing requires your body and you to actively participate in this healing. If you are unwilling to address the root causes and change the lifestyle factors that disrupted your health in the first place, the biologics can amplify your healing signals, but you have to create the internal environment where healing can actually happen. Dr. Deb Muth 49:56So, I hope this episode has helped you understand regenerative medicine more clearly. Share it with somebody who’s looking for healing beyond the conventional approaches. And until next time, this has been Let’s Talk Wellness Now. Have a blessed day. >> Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Dr. Deb Muth 50:16Please note that the views and information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its management, or our partners. Each affiliate, sponsor, and partner is an independent entity with its own perspectives. Today’s content is provided forformational and educational purposes only and should not be considered specific advice, whether financial, medical, or legal. Dr. Deb Muth 50:41While we strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique circumstances. We encourage you to consult with a qualified professional to address your individual needs. Your use of information from this broadcast is entirely at your own risk. Dr. Deb Muth 51:00By continuing to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its associates harmless from any claims or damages arising from the use of this content. We may update this disclaimer at any time, and changes will take effect immediately upon posting or broadcast. Thank you for tuning in. We hope you find this episode both insightful and thought-provoking. Listener discretion is advised.The post Episode 265 – The Future of Healing: How Exosomes Re-Educate Your Body to Heal Itself first appeared on Let's Talk Wellness Now.

Could a simple mineral deficiency be driving mitochondrial dysfunction in autism? In this episode I sit down with Melissa Atchley from MitoSynergy to hear her personal story of using BioCopper1 with her son on the autism spectrum — and the changes she saw that no one expected. I break down the science behind it: Dr Richard Frye's research showing Complex IV dysfunction in children with ASD, the brand new April 2026 Science Advances paper linking copper deficiency directly to ASD-like behaviours through mitochondrial damage and impaired myelination, and why the type of copper matters — Cu1+ vs Cu2+ — more than most people realise. We also cover MitoSynergy's new MitoActivator MAX (4x the strength of the standard formula), the hair greying reversal angle, athletic performance benefits, and practical dosing guidance. If you or someone you love is navigating autism, fatigue, grey hair, or just wants to understand why copper might be the most overlooked mineral in health — this one is worth your time. Get yours in my shop: https://shop.lisatamati.com/products/mitoactivator-max-max-strength-biocopper1-supplement-60-capsmitosynergy-mitoactivator-max?_pos=2&_sid=5c471c21c&_ss=r   Or use code LisaTamati at Mitosynergy.com for your discount   

Just in time for Mother's Day, Liat brings on her mom, Melanie, for a raw convo about raising Liat's brother who has autism and intellectual disabilities. They cover everything from public behavior incidents and Chuck E. Cheese trauma to marriage strain, group home fears, and the chaos of parenting before insurance-covered ABA and Facebook support groups even existed.Melanie opens up about the lifelong commitment and all the emotions that come with raising a child with ASD, and why he's been one of the greatest blessings of her life. This one will make you laugh, cry, call your mom, and maybe start filling out Medicaid waiver paperwork immediately.Connect with Behavior BitchesInsta: @behaviorbitchespodcastFacebook: Behavior Bitches PodcastWebsite: BehaviorBitches.comContact Us: For podcast inquiries, episode ideas, or just to say hi, email us at behaviorbitches@studynotesaba.com Leave us a 5-star review in the Apple Podcast App so we can read it to everyone during our episodes and make us super happy!Looking for BCBA Exam Prep or CEUs?• Whether you need help passing the BCBA exam or are looking to earn CEUs, Study Notes ABA has you covered. Check out our website for comprehensive exam prep materials, prep courses, and CEUs• Test Prep: StudyNotesABA.com• CEUs: CEU.StudyNotesABA.com• PairABA: PairABA.com

It's Opening Day at Assiniboia Downs, and we have full coverage all season on In the Money Media. Check out the brand new $3 Prime Pick 3 on the first 3 and the last 3 races on the card. $50,000 Guaranteed Pick 4 on the last 4 races with $1 minimum. These player-friendly wagers and large handle make ASD the place to play every week! PTF and Mikee P. look at the last 4 races on the Card for the Opening Tuesday night - looking to find value.

It's Opening Day at Assiniboia Downs, and we have full coverage all season on In the Money Media. Check out the brand new $3 Prime Pick 3 on the first 3 and the last 3 races on the card. $50,000 Guaranteed Pick 4 on the last 4 races with $1 minimum. These player friendly wagers and large handle make ASD the place to play every week! PTF and Mikee P. look at the last 4 races on the Card for the Opening Tuesday night - looking to find value.

Jordyn Montique's personal and professional experiences created a passion for addressing cultural responsiveness in serving marginalized children with disabilities, and their families. Jordan, Barry and Dave discuss how essential it is to be in culturally, responsive, and for professionals to be aware of their own cultural biases in developing trusting relationships with children and their families. Learn more and access to the transcripts on our website!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr Kirk Honda continues his lecture on limerence. (Intro) May 6, 2026This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/KIRK to get 10% off your first month.00:00 Revisiting the definition of limerence23:08 How is limerence differentiated from ASD?27:09 How is limerence differentiated to ADHD?34:43 Reviewing the differencesSupport us by... Become a member: https://www.youtube.com/channel/UCOUZWV1DRtHtpP2H48S7iiw/joinBecome a patron: https://www.patreon.com/PsychologyInSeattleContact us/more info... Email: https://www.psychologyinseattle.com/contactAbout Dr. Kirk: https://www.psychologyinseattle.com/about-dr-kirk-hondaWebsite: https://www.psychologyinseattle.comGet stuff... Merch: https://psychologyinseattle-shop.fourthwall.com/KIRKgram (like Cameo): https://www.psychologyinseattle.com/kirkgramThe Psychology In Seattle Podcast ®Trigger Warning: This episode may include topics such as assault, trauma, and discrimination. If necessary, listeners are encouraged to refrain from listening and care for their safety and well-being. Disclaimer: The content provided is for educational, informational, and entertainment purposes only. Nothing here constitutes personal or professional consultation, therapy, diagnosis, or creates a counselor-client relationship. Topics discussed may generate differing points of view. If you participate (by being a guest, submitting a question, or commenting) you must do so with the knowledge that we cannot control reactions or responses from others, which may not agree with you or feel unfair. Your participation on this site is at your own risk, accepting full responsibility for any liability or harm that may result. Anything you write here may be used for discussion or endorsement of the podcast. Opinions and views expressed by the host and guest hosts are personal views. Although we take precautions and fact check, they should not be considered facts and the opinions may change. Opinions posted by participants (such as comments) are not those of the hosts. Readers should not rely on any information found here and should perform due diligence before taking any action. For a more extensive description of factors for you to consider, please see www.psychologyinseattle.com

Today, I welcome back pediatrician, Dr. Mary H Jones. Mary has been a guest on the show and contributed to Uniquely Us, chapter 11, discussing additional biases and stigma BIPOC individuals can face in getting an accurate diagnosis and accommodations. Dr. Jones shares her experience as a pediatrician and mom of neurodivergent kids and in a neurodiverse marriage.Today, Dr. Stephanie and Dr. Jones discuss early intervention and how diagnosis impacts accommodations and interventions. Dr. Mary Jones is licensed in over 20 states and specializes in ADHD and ASD diagnosis in children, teens, and adults.Dr. Stephanie asks Dr. Jones when she uses the three most well-known measures: the ADOS, CARS, and MIGDAS-2Today, with a focus on diagnosis, Patreon with Dan and Stephanie will discuss a different topic About Dr. Mary H. Jones & Bright StartsAt Bright Starts, we're dedicated to helping children, teens, and young adults reach their full potential through early, accurate ADHD evaluations and autism diagnostic services. We understand that every individual is unique — and so is their journey. That's why we provide personalized evaluations, compassionate guidance, and clear next steps for families navigating developmental concerns.https://brightstartshealth.com/home Dr. Mary "What is Autism?"https://brightstartshealth.com/about-us Mary H. Jones, MD, FAAPAssesses with ADOS-2, CARS and MIGDAS-2​Dr. Mary Jones believes there is greatness in each of us and is passionate about equipping and empowering women to reach their fullest potential. Throughout her life and career, she has had the privilege of working to empower and equip women and girls to be their best selves. Dr. Mary has also completed a study in autism as a speciality through PESI, and has become an Autism Spectrum Disorder Clinical Specialist. Her vision is to see women living out their purpose and affecting change in their worlds. She is an NT married to a neurodivergent spouse and the mother of a son on the autism spectrum.   

Send us Fan MailDr. Ayesha Khalid, resident at Marshall University, presents findings from a large meta-analysis pooling data from eight national registries across Europe — covering 2.5 million pregnancies — to examine whether prenatal acetaminophen exposure is truly linked to autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) in children. She shares why the association with ASD largely disappears when accounting for heterogeneity and confounders, why the previously reported link with ADHD appears significantly smaller than what has been published, and why publication bias may have inflated the estimates we have been working from. She also addresses the critical limitation that no patient-level dose or timing data was available, why the risk-benefit calculation around fever control in pregnancy complicates any simple recommendation, and what kind of studies — ideally sibling-controlled designs like those done in Sweden — would be needed to actually settle this question.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

EPISODE 156HANS CHRISTIAN ANDERSEN: HIS NEURODIVERGENT JOURNEY, AS SHARED BY AUTISTIC CHILDREN'S AUTHOR, SANDRA NICKELIt is now widely accepted that Hans Christian Anderson, renowned Danish author of children's books, was autistic. Sandra Nickel, an award-winning and autistic children's author brings Andersen's story to life in a beautiful book, “The Real Ugly Duckling”. Sandra, Barry and Dave discuss her motivation for writing her book, and the special qualities of his life's journey that can be so enlightening and affirming for children, adults, and all people who have, or who even may not have neurodivergent individuals in their lives.Learn more on our website!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.