Podcasts about PLOS One

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Best podcasts about PLOS One

Latest podcast episodes about PLOS One

Beyond the Book
Preprints, Retractions & The Scientific Record

Beyond the Book

Play Episode Listen Later May 15, 2022 20:26


A peer-reviewed article published this month in PLOS ONE has examined what happens in the scientific record when journal-published versions of articles are retracted in cases of research previously available on preprint servers.

Questioning Medicine
Episode 195: 195. Medical Update-- GERD guidelines, IV iron, bariatric surgery, DOAC and the Frail Pmts

Questioning Medicine

Play Episode Listen Later May 5, 2022 25:01


European Heart JournalBariatric surgery and cardiovascular disease: a systematic review and meta-analysisEur Heart J 2022 Mar 04;[EPub Ahead of Print], SL van Veldhuisen, TM Gorter, G van Woerden, RA de Boer, M Rienstra, EJ Hazebroek, DJ van Veldhuisen  39 studies, all prospective or retrospective cohort studies, showed Bariatric surgery is associated with a reduced hazard ratio (HR) of CV morality (0.59), all-cause mortality (0.55), incident HF (0.50), myocardial infarction (0.58) and stroke (0.64) Authors state “”The present systematic review and meta-analysis suggests that bariatric surgery is associated with reduced all-cause and CV mortality, and lowered incidence of several CV diseases in patients with obesity. Bariatric surgery should therefore be considered in these patients.””” Here is the problem and I have said it before—“no randomized control trials examining the effect of bariatric surgery on CV outcomes,”Among frail patients with AF, OAC treatment was associated with a positive net clinical outcome. Direct OACs provided lower incidences of stroke, bleeding, and mortality, compared with warfarin. Just talked recently about continue doac in hospice and everyone agrees that is bad but ultimately there are very few conditions in which you should not resume anticoag—even in those with GI bleed, falls, or subachrnoid hemerage—the data suggest the pts are better off back on anticoag. Well this study looked at the frail. In this retrospective cohort study analyzed 83 635 patients  with mean age 78.5 those individuals who were on ORAL anticoag(doac or warfarin) had overall lower risks of ischemic stroke (HR, 0.91) and cardiovascular death (HR, 0.52), with no significant difference in major bleeding (HR, 1.02),   Bottom line- restart the OAC – even in the frail to prevent the outcomes we really care about like stroke and death    Dave CV et al. Risks for anaphylaxis with intravenous iron formulations: A retrospective cohort study. Ann Intern Med 2022 Mar 29; [e-pub]. (https://doi.org/10.7326/M21-4009. opens in new tab) Anaphylaxis occurs rarely with intravenous (IV) iron does happen but how often does it happen??  It is a mystery—till now Using a retrospective cohort design, investigators assessed 167,000 U.S. Medicare patients who received IV iron products between 2013 and 2018. Patients who had received IV iron within the previous year and those with end-stage renal disease, HIV infection, history of anaphylactic reaction, or recent transfusions were excluded. This is the perfect study for observational data. We know it happens so we look at a large data set and try to see how often it happens. In this population of older adults, the rate of anaphylaxis for iron dextran was ≈0.1%, but it was closer to 0.01% for iron sucrose, ferric gluconate, and ferric carboxymaltose (can give once== carboxy and dextran). As indications have broadened for use of IV iron in managing various clinical conditions (e.g., heart failure, chronic kidney disease) when iron deficiency is present, clinicians might use these data to inform selection of a preparation.  A lot depends on cost and availability but these are good numbers to have in your head for the anaphylaxis event rate... Sure it might take 5 years or even 10 years but some of the outcomes like MI and HF will easily hit in the first 5-10 years!! This RCT could be done tomorrow! Instead we continue to do this observational studies and say look how great this procedure is!! Well maybe it is ‘healthy' patient bias—you have two pts with BMI of 40 but one seems motivated is working out eating better- trying to take all the right steps and the other hasn't left the couch in 6 years. The one that is active then gets referred for bariatric surgery and when we match them up we say LOOK AT THIS THE BARIATRIC SURGERY person did so much better. WEEELLLLLL that pt was likely going to do better anyways!!! AT this point everyone know that bariatric surgery seems to have great CV outcomes in retrospective and prospective observational trials we have done enough of them.. THIS analysis had 39 STUDIES—39!!!! We don't need 30 more we need and RCT!!!     Katz PO et al. ACG clinical guideline for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol 2022 Jan; 117:27. (https://doi.org/10.14309/ajg.0000000000001538. opens in new tab) Much of this guideline is worthwhile for nongastroenterologists.  An empirical 8-week trial of a proton-pump inhibitor (PPI), given once daily, is recommended for a patient who has classic heartburn and regurgitation but no alarm symptoms.  PPIs should be taken 30 to 60 minutes before a meal, because they bind to proton pumps that have been stimulated by meals. Bedtime dosing is discouraged because this is less effective than a predinner dose in acid control GERD is thought to contribute to various extraesophageal symptoms, including chronic cough, hoarseness, and laryngitis; however, a causal relation often is unclear in any given patient. For patients with extraesophageal symptoms — but no heartburn or regurgitation — the authors argue against empirical PPI therapy  After 8 weeks you STOP the PPI--PPI nonresponders, and PPI responders whose symptoms return after an 8-week PPI course, should be evaluated with Endoscopy about 2 to 4 weeks off PPIs.  If endoscopy is normal, ambulatory pH monitoring (off treatment) is the next step. authors encourage intermittent or “on-demand” (rather than indefinite) PPI therapy in patients with no history of high-grade esophagitis or Barrett esophagus. IF requires ongoing PPI therapy for symptom control should use the lowest effective dose.I do like these guidelines cause they seem to be great at making sure PPI are stopped (ideally). I do hate these guidelines cause getting a scope after 8 weeks of a PPI with reoccurring symptoms seems like a lot of scopes will be done. Especially because some people get rebound gerd when going off of a PPI. As the authors state “One area of controversy relates to abrupt PPI discontinuation and potential rebound acid hypersecretion, resulting in increased reflux symptoms. Although rebound acid hypersecretion has been demonstrated to occur in healthy controls, strong evidence for an increase in symptoms after abrupt PPI withdrawal is lacking.”  -- none of this is super strong evidence!!! This seems like a lot of scopes.The fear of progression to adenocarcinoma with Barrett's Esophagus would make for an easy decision for prolonged PPI use, however, a systematic review and meta-analysis published in PLoS One - Hu Q, Sun TT, Hong J, et al. Proton Pump Inhibitors Do Not Reduce the Risk of Esophageal Adenocarcinoma in Patients with Barrett's Esophagus: A Systematic Review and Meta-Analysis. PLoS One 2017;12(1):e0169691. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169691 found no protective effect.1And even though long term use of PPI is associated with many bad outcomes even the authors state -  “””“PPIs are the most effective medical treatment for GERD. Some medical studies have identified an association between the long-term use of PPIs and the development of numerous adverse conditions including intestinal infections, pneumonia, stomach cancer, osteoporosis-related bone fractures, chronic kidney disease, deficiencies of certain vitamins and minerals, heart attacks, strokes, dementia, and early death. “” the authors go on to say “””Those studies have flaws, are not considered definitive, and do not establish a cause-and-effect relationship between PPIs and the adverse conditions. High-quality studies have found that PPIs do not significantly increase the risk of any of these conditions except intestinal infections. .”””  THIS IS ALSO GARBAGE!!! The reason the high quality studies don't show this is because most studies are only 8-12 weeks long PPI you need long term trials which most people are on and you have to power your study so large to find a super rare outcome that observational data is the best we are ever going to have for this particular finding. I know the authors knew this but it didn't fit their agenda…Which is my last point—although we will never know—all but one of the authors has or is taking big pharma money. Take home if you are following the guideslines-- start PPI only for Gerd like symptoms. Make sure taking the PPI correctly. Stop after 8 weeks. If it reoccurs then 2-4 weeks later off the PPI they need a scope and if the scope is normal then they need PH monitoring. Then the rec is for PRN PPI.  

Herpetological Highlights
108 In The Hall of The Mountain Kingsnake

Herpetological Highlights

Play Episode Listen Later May 3, 2022 33:34


Are mountain kingsnakes multiple species? We try to decide. Become a Patreon: https://www.patreon.com/herphighlights Full reference list available at: www.herphighlights.podbean.com  Main Paper References: Myers, E. A., Rodríguez-Robles, J. A., Denardo, D. F., Staub, R. E., Stropoli, A., Ruane, S., & Burbrink, F. T. (2013). Multilocus phylogeographic assessment of the California Mountain Kingsnake (Lampropeltis zonata) suggests alternative patterns of diversification for the California Floristic Province. Molecular Ecology, 22(21), 5418–5429. https://doi.org/10.1111/mec.12478 Species of the Bi-Week: Székely, P., Székely, D., Ordó ñez-Delgado, L., Armijos- Ojeda, D., & Vörös, J. (2021). Our unknown neighbor: A new species of rain frog of the genus Pristimantis (Amphibia: Anura: Strabomantidae) from the city of Loja, southern Ecuador. PLoS ONE, 16(10 October), 1–24. https://doi.org/10.1371/journal.pone.0258454 Other Mentioned Papers/Studies: Chambers EA, Hillis DM. (2019). The Multispecies Coalescent Over-splits Species in the Case of Geographically Widespread Taxa. Systematic Biology:syz042. https://doi.org/10.1093/sysbio/syz042. Music: Intro/outro – Treehouse by Ed Nelson Species Bi-week theme – Mike Mooney Other Music – The Passion HiFi, www.thepassionhifi.com

Sara先生のペットの暮らしと健康 No.2(Podcast with Holistic Vet Sara)
#607. MCTオイルが犬猫の腸活にもイイ?(Voicyライブの続編)

Sara先生のペットの暮らしと健康 No.2(Podcast with Holistic Vet Sara)

Play Episode Listen Later Apr 28, 2022 11:28


<お知らせ> ◆Voicy新チャンネル開設!【獣医Sara先生の一問一答】 https://bit.ly/3sLljup ◆犬猫にもイイの?MCTオイル:認知症・てんかんに(アーカイブ) <Standfm メンバーシップ:メンバーになりませんか?> 【ペットのホリスティックケアCLUB】 みんなでギネス長寿記録を目指す! 5つの特典アリ!【人もペットも一緒に健康で長生きしよう】プロジェクト始動!

Glaretum
Uso de bacterias para construir asentamientos en Marte

Glaretum

Play Episode Listen Later Apr 27, 2022 1:57


En colaboración con la Organización de Investigación Espacial de la India (ISRO), un equipo de investigadores del Instituto Indio de Ciencias (IISc) ha desarrollado un método sostenible para fabricar ladrillos con suelo marciano, utilizando bacterias y urea. Estos "ladrillos espaciales" se pueden usar para construir estructuras similares a edificios en Marte que podrían facilitar el asentamiento humano en el planeta rojo. El método para fabricar estos ladrillos espaciales se describe en un estudio publicado en PLOS ONE.

WBAP Morning News Podcast
WBAP Morning News: Dr. Joey Speers

WBAP Morning News Podcast

Play Episode Listen Later Apr 20, 2022 6:02


Many of us think a decrease in cognitive ability is part of the natural aging process—the so-called "senior moments" that happen more frequently as we get older. Forgetting to do something or having small details slip your mind might not seem like a serious issue, but these brain blips may be a sign of mild cognitive impairment (MCI), which can lead to dementia down the line. According to the Mayo Clinic, things like avoiding excessive alcohol use, limiting exposure to air pollution, exercising regularly, and getting good sleep at night can help keep our brains healthy—but a recent study found that a common medication could be thwarting those efforts. Women who took certain prescription pharmaceuticals were more likely to have decreased cognitive ability over time.  A study published in PLOS ONE last month found that women who frequently took antibiotics during midlife showed faster rates of cognitive decline than those who did not. See omnystudio.com/listener for privacy information.

Creative Training Techniques - The Bob Pike Group

Being on camera is intense work! Why make your learners work so hard in a Zoom session? Get rid of the eye glaze. Becky has some tips to avoid the burnout from overusing virtual platforms. Early eye gaze research Argyle, M., & Dean, J. (1965). Eye-contact, distance and affiliation. Sociometry, 28(3), 289–304. https://doi.org/10.2307/2786027 Bailenson, J. N., Blascovich, J., Beall, A. C., & Loomis, J. M. (2001). Equilibrium theory revisited: Mutual gaze and personal space in virtual environments. Presence, 10(6), 583–598. https://doi.org/10.1162/105474601753272844   Takac, M., Collett, J., Blom, K. J., Conduit, R., Rehm, I., & Foe, A. D. (2019). Public speaking anxiety decreases within repeated virtual reality training sessions. PLOS ONE, 14(5). https://doi.org/10.1371/journal.pone.0216288   Non verbal/verbal Croes, E. A. J., Antheunis, M. L., Schouten, A. P., & Krahmer, E. J. (2019). Social attraction in video-mediated communication: The role of nonverbal affiliative behavior. Journal of Social and Personal Relationships, 36(4), 1210–1232. https://doi.org/10.1177/0265407518757382 Purchase Becky's new book here: http://store.bobpikegroup.com/bk-creative-training-a-train-the-trainer-field-guide/ Podcast available on iTunes here:  https://itunes.apple.com/us/podcast/creative-training-techniques/id862555469?mt=2 And on the web here: http://www.bobpikegroup.com/Resources/podcasts-and-videos

Neurosapiens
34 | Celui où on parlait de l'impact de la musique sur le cerveau

Neurosapiens

Play Episode Listen Later Apr 6, 2022 14:10


Soutenir et s'abonner à Neurosapiens ♥️La musique a un pouvoir dingue sur notre humeur, notre journée, notre concentration… mais quel est ce pouvoir précisément ? Quel est réellement l'impact et, on peut le dire, les bienfaits d'écouter de la musique sur notre cerveau ? Quel est le pouvoir de la musique sur votre outil le plus puissant ? Réponse dans cet épisode ! Production, animation, réalisation et illustration : Anaïs RouxInstagram : https://www.instagram.com/neurosapiens.podcast/neurosapiens.podcast@gmail.comMusique d'intro KEEP ON GOINGMusique proposée par La Musique LibreJoakim Karud - Keep On Going : https://youtu.be/lOfg0jRqaA8Joakim Karud : https://soundcloud.com/joakimkarudSources A. R. Harvey, Links between the neurobiology of oxytocin and human musicality, Frontiers in Human Neuroscience, 2020.A. Habibi et al., Childhood music training induces change in micro and macroscopic brain structure : Results from a longitudinal study, Cerebral Cortex, 2018.Mehta, R., Zhu, R., & Cheema, A. (2012). Is noise always bad? Exploring the effects of ambient noise on creative cognition. Journal of Consumer Research, 39(4), 784-799.méthodeRitter SM, Ferguson S. Happy creativity: Listening to happy music facilitates divergent thinking. PLoS One. 2017 Sep 6;12(9):e0182210. doi: 10.1371/journal.pone.0182210. PMID: 28877176; PMCID: PMC5587106.Salimpoor VN, Benovoy M, Larcher K, Dagher A, Zatorre RJ. Anatomically distinct dopamine release during anticipation and experience of peak emotion to music. Nat Neurosci. 2011 Feb;14(2):257-62. doi: 10.1038/nn.2726. Epub 2011 Jan 9. PMID: 21217764.LIU, L., & KAGER, R. (2017). Perception of tones by bilingual infants learning non-tone languages. Bilingualism: Language and Cognition, 20(3), 561-575. doi:10.1017/S1366728916000183Liu, L., Kager, R. Enhanced music sensitivity in 9-month-old bilingual infants. Cogn Process 18, 55–65 (2017). https://doi.org/10.1007/s10339-016-0780-7Zatorre RJ, Salimpoor VN. From perception to pleasure: music and its neural substrates. Proc Natl Acad Sci U S A. 2013 Jun 18;110 Suppl 2(Suppl 2):10430-7. doi: 10.1073/pnas.1301228110. Epub 2013 Jun 10. PMID: 23754373; PMCID: PMC3690607. Voir Acast.com/privacy pour les informations sur la vie privée et l'opt-out. Become a member at https://plus.acast.com/s/neurosapiens.

VONDT - en podcast om muskel- og skjelettplager
EP 40: Kjernestabilitet m/ Gøran Paulsen og Lars Haugvad

VONDT - en podcast om muskel- og skjelettplager

Play Episode Listen Later Mar 28, 2022 64:13


Få konsepter har skapt like sterke trender innen både trening og muskel- og skjelettfeltet som core stability – eller kjernestabilitet på norsk. Det har vokst frem en helt egen industri innen både trening og helse, som har ført til en helt egen forståelse av hvordan vi ser på kroppen og kontrollen over motoriske oppgaver. Så har deg seg en gang sånn at vi i blant er litt raske til å omfavne nye konsepter, og det stilles nå stadig flere kritiske spørsmål til hele konseptet om vi faktisk trenger å stabilisere kjernen vår på en spesifikk måte – både med tanke på trening, prestasjon og helse. For, hva er egentlig kjernestabilitet. Hva definerer vi som kjernen? Kan vi skille på lokal og global muskulatur, og er det mulig å selektivt trene det ene uten det andre? Er det i så fall hensiktsmessig? Og hvilken betydning har dette konseptet for pasientene våre? Har folk instabile rygger? Kan ryggplager forebygges av å trene kjernestabilitet? Eller har vi skapt forklaringsmodeller bygget på et luftslott?Dette, og mer, snakker vi med Gøran Paulsen og Lars Haugvad om. Gøran er Professor i idrettsfysiologi ved Norges Idrettshøgskole. Han er Utdannet fysioterapeut og har en Doktorgrad i idrettsfysiologi fra Norges idrettshøgskole, som omhandlet restitusjon og adaptasjon til arbeidsinduserte muskelskader (2004-2009). Fra 2013-2019 ledet han Olympiatoppens kraft/styrke-avdeling der han nå også jobber som fagkonsulent.Lars Haugvad er manuellterapeut, spesialist i idrettsfysioterapi og jobber på Olympiatoppen med oppfølging av primært landslagene i snowboard, beachvolley og seiling og er tidligere leder for helseteamet til skihopplandslaget for damer og herrer. Han er også ansvarlig for screening og monitoreringsprogrammet for de norske olympiske utøverne. Lars er en ettertraktet kurs- og foredragsholder, med sin egen fagdag om styrketrening, og gjestet oss i episode 6, som er en av våre mest populære episoder til nå.Referanser:Bergmark, A., Stability of the lumbar spine. A study in mechanical engineering. Acta Orthop Scand Suppl, 1989. Hodges, P.W., The role of the motor system in spinal pain: implications for rehabilitation of the athlete following lower back pain. J Sci Med Sport, 2000.Howe, L.P. and G. Lehman, Getting out of neutral: the risks and rewards of lumbar spine flexion during lifting exercises. Strength Cond J, 2021. Huxel Bliven KC, Anderson BE. Core stability training for injury prevention. Sports Health. 2013.Lederman, E., The myth of core stability. J Bodyw Mov Ther, 2010. Low, Matthew. A Time to Reflect on Motor Control in Musculoskeletal Physical Therapy Journal of Orthopaedic & Sports Physical Therapy. 2018 McGill, S., Core training: Evidence translating to better performance and injury prevention. Strength Cond J, 2010. Saeterbakken, A.H., et al., The Effects of Trunk Muscle Training on Physical Fitness and Sport-Specific Performance in Young and Adult Athletes: A Systematic Review and Meta-Analysis. Sports Med, 2022.Saeterbakken AH, Loken E, Scott S, Hermans E, Vereide VA, et al. Effects of ten weeks dynamic or isometric core training on climbing performance among highly trained climbers. PLOS ONE. 2018.Wirth, K., et al., Core Stability in Athletes: A Critical Analysis of Current Guidelines. Sports Med, 2017. 47(3): p. 401-414.Musikk:Joseph McDade - Mirrors

Medical Myths, Legends & Fairytales
Is it possible to regenerate our brain? with Dr. Greg Eckel

Medical Myths, Legends & Fairytales

Play Episode Listen Later Mar 28, 2022 45:25


Can the brain repair itself? Can it regenerate after damage? Will there be a full recovery after a brain injury?  I bring in a friend to talk about the latest advances in neuronal repair. In practice since 2001, Dr. Greg Eckel, co-founder of Nature's Cure clinic in Portland where he shares what he calls "Sarieah's gifts" with the world, has focused on chronic degenerative and neurodegenerative diseases for many years. Between the latest online fads and the crazy media headlines, it's easier more than ever to get confused about your health. If you want to make better decisions about your health so you can feel better and live longer, you've come to the right place. As a loving husband and clinician, he took a deep dive into medical research looking for cures to his wife's Creutzfeldt-Jakob disease, a rare, chronic neurodegenerative condition with no known cure. While he didn't find a solution for Sarieah, the information he discovered and now uses in his clinic is showing promise for thousands of people.    Key takeaways: [1:37] Introduction to Dr. Greg Eckel[2:24] Can the brain really regenerate?[6:11] What is the time frame for the brain to regenerate and what is the success rate?[7:20] VSEL's - Very Small Embryonic-Like Stem Cells[9:18] Main diseases' underlying categories for neurodegeneration - prion, auto-immune and traumatic brain injuries.[11:25] FAN-C approach - a framework that Dr. Eckel have created to evaluate, explore and develop a program for proper diagnosis.[12:43] How Dr. Eckel got into prionic activity.[14:00] Clinician's own grief as experience and inspiration to help people. [17:45] Getting your grief and emotions out.[24:27] What happens in the neurodegeneration FAN-C approach assessment?[25:15] Other causes of neurodegeneration[26:00] Why do proteins misfold? [26:50] The Braak's hypothesis of parkinson's disease[30:02] Homeodynamic regulation[32:14] Cellular regeneration - VSEL's[36:53] Hyperbaric oxygen - originally designed and developed for divers and helps heal the brain for regeneration.[39:41] Photobiomodulation - a light therapy using low level laser.[40:45] Acupuncture and Chinese medicine encourage proper blood flow and help the body and the brain heal.[42:56] Nature Cures Clinic and the Cloudhands and superbrain yoga videos.[43:35] Closing Topic references:   https://naturecuresclinic.com/brain-regeneration/   https://poddtoppen.se/podcast/1339733591/the-spectrum-of-health-with-dr-christine-schaffner/the-future-is-brain-regeneration-dr-greg-eckel-with-dr-christine-schaffner   https://pubmed.ncbi.nlm.nih.gov/28243222/   https://sitn.hms.harvard.edu/flash/2010/issue65/   https://www.nigms.nih.gov/education/fact-sheets/Pages/regeneration.aspx For more details about Dr. Greg Eckel, visit his website www.naturecuresclinic.com or join his exercises, QI gong and Super Brain yoga through www.naturecuresclinic.com/qigong. You can also book a consultation call with his team through naturecuresclinic.com/book-a-call.   Follow Dr. Greg Eckel on his social media accounts:Facebook: https://www.facebook.com/pg/NatureCuresClinic/posts/  Instagram: https://www.instagram.com/naturecurespdx/?hl=en LinkedIn: https://www.linkedin.com/in/drgregeckel/  Twitter: @drgreckel     HBOT and Brain health Resources:   “Hyperbaric Oxygen Alleviates Secondary Brain Injury After Trauma Through Inhibition of TLR4/NF-κB Signaling Pathway”. Meng XE, Zhang Y, Li N, Fan DF, Yang C, Li H, Guo DZ, Pan SY. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 2016 Jan 26; 22: 284-288 PMC [article] PMCID: PMC4734681, PMID: 26812205, DOI: 10.12659/MSM.894148 Boussi-Gross R, Golan H, Fishlev G, Bechor Y, Volkov O, Bergan J, Friedman M, Hoofien D, Shlamkovitch N, Ben-Jacob E, Efrati S. “Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury - randomized prospective trial”. PLoS One. 2013 Nov 15;8(11):e79995. doi: 10.1371/journal.pone.0079995. eCollection 2013. PubMed [citation] PMID: 24260334, PMCID: PMC3829860 Thom SR, Bhopale VM, Velazquez OC, Goldstein LJ, Thom LH, Buerk DG. “Stem cell mobilization by hyperbaric oxygen”. Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1378-86. Epub 2005 Nov 18. PubMed [citation] PMID: 16299259 “ROS and Brain Diseases: The Good, the Bad, and the Ugly”. Popa-Wagner A, Mitran S, Sivanesan S, Chang E, Buga AM. “Oxidative Medicine and Cellular Longevity”. 2013 Dec 5; 2013: 963520 PMC [article] PMCID: PMC3871919, PMID: 24381719, DOI: 10.1155/2013/963520 “Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?”. Mu J, Krafft PR, Zhang JH. Medical Gas Research. 2011 Jun 27; 1: 14 PMC [article] PMCID: PMC3231808, PMID: 22146131, DOI: 10.1186/2045-9912-1-14   PARKINSONS REFERENCES:  (etiology, causes, treatments)   “d-β-Hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's Disease”. Kashiwaya Y, Takeshima T, Mori N, Nakashima K, Clarke K, Veech RL. Proceedings of the National Academy of Sciences of the United States of America. 2000 May 9; 97(10): 5440-5444 PMC [article] PMCID: PMC25847, PMID: 10805800, DOI: 10.1073/pnas.97.10.5440 Han L, Xie YH, Wu R, Chen C, Zhang Y, Wang XP. “Traditional Chinese medicine for modern treatment of Parkinson's disease”. Chin J Integr Med. 2017 Aug;23(8):635-640. doi: 10.1007/s11655-016-2537-7. Epub 2017 Jan 20. Review. PubMed [citation] PMID: 28108911 Karlsson O, Lindquist NG. “Melanin affinity and its possible role in neurodegeneration”. J Neural Transm (Vienna). 2013 Dec;120(12):1623-30. doi: 10.1007/s00702-013-1062-5. Epub 2013 Jul 3. Review. PubMed [citation] PMID: 23821370 “Therapeutic potential of autophagy-enhancing agents in Parkinson's disease”. Moors TE, Hoozemans JJ, Ingrassia A, Beccari T, Parnetti L, Chartier-Harlin MC, van de Berg WD. Molecular Neurodegeneration. 2017 Jan 25; 12: 11 PMC [article] PMCID: PMC5267440, PMID: 28122627, DOI: 10.1186/s13024-017-0154-3 Goldman SM. “Environmental toxins and Parkinson's disease”. Annu Rev Pharmacol Toxicol. 2014;54:141-64. doi: 10.1146/annurev-pharmtox-011613-135937. Epub 2013 Sep 16. Review. PubMed [citation] PMID: 24050700 Agim ZS, Cannon JR. “Dietary factors in the etiology of Parkinson's disease”. Biomed Res Int. 2015;2015:672838. doi: 10.1155/2015/672838. Epub 2015 Jan 20. Review. PubMed [citation] PMID: 25688361, PMCID: PMC4320877 Montgomery EB Jr. “Heavy metals and the etiology of Parkinson's disease and other movement disorders”. Toxicology. 1995 Mar 31;97(1-3):3-9. Review. PubMed [citation] PMID: 7716790 Ward RJ, Dexter DT, Crichton RR. “Chelating agents for neurodegenerative diseases”. Curr Med Chem. 2012;19(17):2760-72. Review. PubMed [citation] PMID: 22489724 Hozumi I, Hasegawa T, Honda A, Ozawa K, Hayashi Y, Hashimoto K, Yamada M, Koumura A, Sakurai T, Kimura A, Tanaka Y, Satoh M, Inuzuka T. “Patterns of levels of biological metals in CSF differ among neurodegenerative diseases”. J Neurol Sci. 2011 Apr 15;303(1-2):95-9. doi: 10.1016/j.jns.2011.01.003. Epub 2011 Feb 2. PubMed [citation] PMID: 21292280 Chu Y, Kordower JH. “The prion hypothesis of Parkinson's disease”. Curr Neurol Neurosci Rep. 2015 May;15(5):28. doi: 10.1007/s11910-015-0549-x. PubMed [citation] PMID: 25868519   What did you learn about today's topic? Let us know by leaving a review! Visit these links to learn more: https://www.drchristianson.com/ Dr. Christianson on Facebook (http://www.facebook.com/DrAlanChristianson/) Dr. Christianson on Instagram (http://www.instagram.com/dralanchristianson/) Subscribe for more Medical Myths, Legends, & Fairytales: Apple Podcasts (https://podcasts.apple.com/us/podcast/medical-myths-legends-fairytales/id1467232418) Spotify (https://open.spotify.com/show/0HaZ75TpOCazsRQSG0AOFs) YouTube (https://www.youtube.com/user/Alannmd/videos)

Dog about Life
Soziales Lernen statt Reiz-Reaktions-Maschine?!

Dog about Life

Play Episode Listen Later Mar 22, 2022 41:10


In der heutigen Folge spricht Patrizia über soziales Lernen. Was ist soziales Lernen und wie unterscheidet es sich von anderen Formen des Lernens, wie etwa dem klassischen oder operanten Konditionieren? Werden wir durch soziales Lernen dem Wesen unserer Hunde eher gerecht als durch Reiz-Reaktionslernen? Müssen wir uns für die eine oder andere Seite entscheiden? Und was hat es außerdem mit dem lerntheoretischen "Wunderkind" namens Do-As-I-Do auf sich? Sind Hunde neben uns Menschen die einzige Art, die zur 1:1 Imitation von vorgezeigten Handlungen fähig sind? Und bestätigt das vielleicht endlich den Glauben, den wir alle eigentlich schon lange in uns tragen, dass unsere Hunde über außerordentliche Intelligenz verfügen oder noch besser uns so sehr lieben, dass sie einfach alles für uns tun? Fragen über Fragen! Patrizia hat Antworten für euch, hört rein! || Kontakt:dogaboutlife@gmail.com|| Instagram: @dogaboutlifePatrizia: @fuxliebe Alice: @minniefairytailAnna: @loewenpfoten|| Logo Credits:Katleen Ackers https://katleenackers.de/|| Music Credits:Music from https://www.zapsplat.com || Weiterbildungstipp: DO AS I DO Trainingsmethode nach Claudia Fugazza. Mehr Infos unter: https://www.doasido.it/|| Quellen:|| Bailey (1986), zitiert nach Nitzschner, Marie, Blogartikel: Hunde, so intelligent wie Kleinkinder https://hundeprofil.de/hunde-so-intelligent-wie-kleinkinder/ || Bräuer, Juliane & Kaminski, Juliane (2011) Was Hunde wissen. Lernen Hunde durch Beobachtung anderer?3. Auflage, S. 67-87, Franckh: Kosmos Verlag, https://doi.org/10.1007/978-3-662-64293-1|| Duranton, C.; Bedossa, T.; Gaunet, F. (2017) Pet dogs synchronise their walking pace with that of their owners in open outdoor areas. Animal Cognition, 21 (2), S. 219 -226 || Fugazza, C.; Moesta, A.; Pogánya, Á., Miklósi, Á. (2018) Presence and lasting effect of social referencing in dog puppies. Animal Behaviour, 141, S. 67-75 || Gansloßer, Udo & Kitchenham Kate (2019) Hundeforschung aktuell. Anatomie, Ökologie, Verhalten, Stuttgart: Franckh-Kosmos-Verlag. || Gansloßer, Udo (2020) Verhaltensbiologie für Hundetrainer. Grundlagen moderner Ethologie. Stuttgart: Franckh-Kosmos-Verlag. || Gerrig, Richard, J. & Zimbardo, Philip G. (2014) Psychologie. Hallbergmoss: Pearson Deutschland GmbH|| Huber, Ludwig; Popovová, Natálie; Riener, Sabine; Salobir, Kaja & Cimarelli, Giulia (2018) Would dogs copy irrelevant actions from their human caregiver? In: Learning & Behabior 46, S. 387-397, https://doi.org/10.3758/s13420-018-0336-z|| Merola, I; Prato-Previde, E.; Marshall-Pescini S. (2012): Dogs' social referencing towards owners and strangers. PloS One 7 (10): e47653 || Merola, I; Prato-Previde, E.; Marshall-Pescini S. (2012): Social referencing in dog owner dyads? Animal Cognition 15, S. 175 - 185 || Nitzschner, Marie, Blogartikel: Konditionierst du noch oder kommunizierst du schon? https://hundeprofil.de/konditionierst-du-noch/ || Pongrácz, Péter (2014) Social learning in dogs. The Social Dog. In: Behavior and Cognition, Academic Press, S. 249-293. http://dx.doi.org/10.1016/B978-0-12-407818-5.00009-7|| Pongrácz, P. et al. (2008) How does dominance rank status affect individual and social learning performance in der dog (Canis familiaris)? Animal Cognition 11 (1), S. 75 - 82

SLP Nerdcast
DLD and Dyslexia: What Does It All Mean for the SLP?

SLP Nerdcast

Play Episode Listen Later Mar 21, 2022 66:32


Get .1 ASHA CEU hereEpisode SummaryDLD isn't a new text abbreviation or IG expression. It's a real thing in the field of SLP and if you don't know about it, you gotta' tune in to get the scoop. This week, Tim DeLuca and Kate Radville- SLP's and doctoral candidates basking in language and literacy nerdom - chat about all things DLD for the SLP. What is DLD? And why is it so important to get a handle on it in the vast and murky sea of semantics that we painfully stir in the SLP field? Kate and Tim explore how challenges with oral language have a domino effect on the attitudes and skills of students, impacting literacy, behavior, and more. You'll gain assessment and intervention tips that hold fast to the golden thread of most SLP Nerdcast episodes - the importance of EBP and collaboration. There are some four letter words (ahem, “dysteachia”) and a big spotlight on resources in this engaging episode that confronts the strong connections between all aspects of the whole student and their whole future. Course AccommodationsThe transcript for this course is provided below. You can also email us at ceu@slpnerdcast.comLearning OutcomesDefine DLD and dyslexia, understand how they are related, and report on at least five behavioral presentations across academic and social settingsUnderstand the SLP's role in assessing and treating both DLD and dyslexia as members of an interdisciplinary team across the lifespanBe able to locate at least five free resources to further explore both DLD and dyslexia and assessment and treatment optionsResources:Bishop, D. V. M., Snowling, M. J., Thompson, P. A., Greenhalgh, T., & CATALISE consortium. (2016). CATALISE: A Multinational and Multidisciplinary Delphi Consensus Study. Identifying Language Impairments in Children. PLOS ONE, 11(7), e0158753. https://doi.org/10.1371/journal.pone.0158753Bishop, D. V. M., Snowling, M. J., Thompson, P. A., Greenhalgh, T., & and the CATALISE-2 consortium. (2017). Phase 2 of CATALISE: A multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology. Journal of Child Psychology and Psychiatry, 58(10), 1068–1080. https://doi.org/10.1111/jcpp.12721Gough, P. B., & Tunmer, W. E. (1986). Decoding, Reading, and Reading Disability. Remedial and Special Education, 7(1), 6–10. https://doi.org/10.1177/074193258600700104Mitchell, M. P., Ehren, B. J., & Towson, J. A. (2020). Collaboration in Schools: Let's Define It. Perspectives of the ASHA Special Interest Groups, 5(3), 732–751. https://doi.org/10.1044/2020_PERSP-19-00125Redmond, S. M., Ash, A. C., & Hogan, T. P. (2015). Consequences of Co-Occurring Attention-Deficit/Hyperactivity Disorder on Children's Language Impairments. Language, Speech, and Hearing Services in Schools, 46(2), 68–80. https://doi.org/10.1044/2014_LSHSS-14-0045Snow, P. C. (2021). Psychosocial Adversity in Early Childhood and Language and Literacy Skills in Adolescence: The Role of Speech-Language Pathology in Prevention, Policy, and Practice. Perspectives of the ASHA Special Interest Groups, 6(2), 253–261. https://doi.org/10.1044/2020_PERSP-20-00120The Simple View of ReadingMulti-Tiered Language Instruction and InterventionDyslexia in the Schools: Assessment and IdentificationDLD and MeThe Florida Center for Reading ResearchThe International Dyslexia AssociationCourse Disclosure - Financial and In-KindFunding for this course was provided by one of our Corporate Sponsors, Language Dynamics Group.Speaker DisclosuresTim DeLuca financial disclosures: Tim is employed by private practice and university.Tim DeLuca non-financial disclosures: Tim is an ASHA member, a certified speech-language pathologist and reading specialist, a doctoral student at the MGH Institute of Health Professions, and a member of the Sail Lab at the Massachusetts institute of health professions. Kate Radville financial disclosures: Kate does not have any financial relationships to disclose. Kate Radville non-financial disclosures: Kate is an ASHA member, a certified speech-language pathologist, and a doctoral student at the MGH Institute of Health Professions. Kate Grandbois financial disclosures: Kate is the owner / founder of Grandbois Therapy + Consulting, LLC and co-founder of SLP Nerdcast. Kate Grandbois non-financial disclosures: Kate is a member of ASHA, SIG 12, and serves on the AAC Advisory Group for Massachusetts Advocates for Children. She is also a member of the Berkshire Association for Behavior Analysis and Therapy (BABAT), MassABA, the Association for Behavior Analysis International (ABAI) and the corresponding Speech Pathology and Applied Behavior Analysis SIG. Amy Wonkka financial disclosures: Amy is an employee of a public school system and co-founder for SLP Nerdcast. Amy Wonkka non-financial disclosures: Amy is a member of ASHA, SIG 12, and serves on the AAC Advisory Group for Massachusetts Advocates for Children.Time Ordered Agenda:15 minutes: Introduction, Disclaimers and Disclosures15 minutes: Descriptions of DLD and dyslexia, how they are related, and behavioral presentations across academic and social settings15 minutes: Descriptions of the SLP's role in assessing and treating both DLD and dyslexia10 minutes: Descriptions of resources to further explore both DLD and dyslexia and assessment and treatment options 5 minutes: Summary and ClosingDisclaimerThe contents of this episode are not meant to replace clinical advice. SLP Nerdcast, its hosts and guests do not represent or endorse specific products or procedures mentioned during our episodes unless otherwise stated. We are NOT PhDs, but we do research our material. We do our best to provide a thorough review and fair representation of each topic that we tackle. That being said, it is always likely that there is an article we've missed, or another perspective that isn't shared. If you have something to add to the conversation, please email us! Wed love to hear from you!A big THANK YOU to our Corporate Sponsor, Language Dynamics Group for the financial support to make this course possible!__SLP Nerdcast is a podcast for busy SLPs and teachers who need ASHA continuing education credits, CMHs, or professional development. We do the reading so you don't have to! Leave us a review if you feel so inclined!We love hearing from our listeners. Email us at info@slpnerdcast.com anytime! You can find our complaint policy here. You can also:Follow us on instagramFollow us on facebookWe are thrilled to be listed in the Top 25 SLP Podcasts!Thank you FeedSpot!

2,56 Quadratmeter – Ein Podcast übers Dolmetschen
E23: Modelle, Multitasking, Muttersprachenprinzip – Dolmetschmythen auf dem Prüfstand

2,56 Quadratmeter – Ein Podcast übers Dolmetschen

Play Episode Listen Later Mar 14, 2022 100:45


Mit den Dolmetschwissenschaftlerinnen und -dozentinnen Martina Behr und Maren Dingfelder-Stone nimmt Michaela Haller zahlreiche Mythen unter die Lupe, die sich mehr oder weniger hartnäckig um den Beruf des Dolmetschers/der Dolmetscherin ranken. Unter anderem geht es um folgende Fragen: Wann sollte man anfangen, Simultandolmetschen zu unterrichten? In welcher Sprache notiert man denn nun eigentlich "richtig"? Und was hat es mit der angeblich besonders ausgeprägten Multitaskingfähigkeit von Dolmetscher*innen auf sich? Spannende Erkenntnisse aus der Dolmetschwissenschaft garantiert. Literatur ANDRES, Dörte. 2002. Konsekutivdolmetschen und Notation. Frankfurt: Peter Lang. BADDELEY, Alan (2012): Working Memory: Theories, Models, and Controversies. BECKER, Wilfried (1990): Notizentechnik. Germersheim: BBK Ges. für moderne Sprachen. BÜHLER, Hildegund (1986): “Linguistic (semantic) and extra-linguistic (pragmatic) criteria for the evaluation of conference interpreters and interpretation”, Multilingua 5 (4), 411-439. COLLADOS AÍS, Ángela (1994/2002): “Quality Assessment in Simultaneous Interpreting: The Importance of Nonverbal Communication”. In: PÖCHHACKER, F. & SHLESINGER, M. (eds.): The Interpreting Studies Reader. London/New York: Routledge, 327-336. FELDWEG, Erich (1996) Der Konferenzdolmetscher im internationalen Kommunikationsprozess. Heidelberg: Julius Groos. FELDWEG, Erich (1990) „Should Conference Interpreters Specialize?“, in: Bowen, David/Bowen, Margareta (eds.), Interpreting – Yesterday, Today, and Tomorrow. Benjamins (161-167). GILE, Daniel: “Directionality in conference interpreting: a cognitive view” in: GODIJNS, R. and M. HINDERDAEL (Eds.). Directionality in interpreting: The ‘retour' or the native? (2005), 9-26. GILE, Daniel. Basic Concepts and Models for Interpreter and Translator Training. Amsterdam & Philadelphia: John Benjamins, 1995. GILLIES, Andrew (2005): Note-taking for Consecutive Interpreting: A Short Course: Routledge. GORTON, A. (2012). 'B' language interpreting: The interpreter's perspective. Forum, 10(2), 61–88. HERBERT, Jean (1952): Handbuch für den Dolmetscher. Leitfaden für den Konferenz-Dolmetscher. Genf: Librairie de l'Université. KAHNEMAN, Daniel (1973): Attention and Effort. Englewood Cliffs, NJ: Prentice-Hall. KALDERON, Eliza (2017): Neurophysiologie des Simultandolmetschens:eine fMRI-Studie mit Konferenzdolmetschern. KOSHKIN R. et al. (2018): “Testing the efforts model of simultaneous interpreting: An ERP study”, PLoS ONE 13(10): e0206129, 1-18. KURZ, Ingrid (1993): “Conference Interpretation. Expectations of Different User Groups”, The Interpreters' Newsletter 5, 13-21. LIM, H.-O. (2005). Working into the B Language: The Condoned Taboo? Meta, 50(4). MACKINTOSH, Jennifer (1999): “Interpreters Are Made Not Born”, Interpreting 4 (1), 67-80. RICCARDI, Alessandra (2002): “Evaluation in Interpreting. Macrocriteria and Microcriteria”. In: HUNG, E. (ed.): Teaching Translation and Interpreting, Building Bridges. Amsterdam/Philadelphia: John Benjamins, 115-125. ROZAN, Jean-François (2006): Mémoires d'avant la nuit. Pointe-à-Pitre: Éditions Jasor. SELESKOVITCH, Danica und M. LEDERER (1989): A Systematic Approach to Teaching Interpretation SEUBERT, Sabine (2019): Visuelle Informationen beim Simultandolmetschen. Eine Eyetracking-Studie: Frank & Timme. SZABÓ, Csilla (2006): “Language choice in note-taking for consecutive interpreting: A topic revisited”. Interpreting 8:2, 129–147. VAN DAM, Helle: “From controversy to complexity: Replicating research and extending the evidence on language choice in note-taking for consecutive interpreting” Interpreting 23:1, 2021. WILSS, Wolfram (1999). Übersetzen und Dolmetschen im 20. Jahrhundert. Saarbrücken: ASKO-Europa-Stiftung. The intro and outro contain parts of the song "Sunset Stroll Into The Wood" by Podington Bear (https://freemusicarchive.org/music/Podington_Bear), released under the Creative Commons BY-NY License (https://creativecommons.org/licenses/by-nc/3.0/us/).

DesAbraçando Árvores
#088 – O back-end da conservação: as engrenagens que fazem a máquina girar

DesAbraçando Árvores

Play Episode Listen Later Mar 14, 2022 47:49


Neste episódio trazemos uma reflexão de nosso host supremo sobre os diferentes perfis e os papeis de quem está na linha de frente e nos bastidores de iniciativas de conservação. Artigos citados no episódio: Cullen L, Stanton JC, Lima F, Uezu A, Perilli MLL, Akçakaya HR. Implications of Fine-Grained Habitat Fragmentation and Road Mortality for Jaguar Conservation in the Atlantic Forest, Brazil. Banks SC, editor. PLoS One. 2016;11: e0167372. doi:10.1371/journal.pone.0167372 Perilli MLL, Lima F, Rodrigues FHG, Cavalcanti SMC. Can Scat Analysis Describe the Feeding Habits of Big Cats? A Case Study with Jaguars (Panthera onca) in Southern Pantanal, Brazil. Crowther MS, editor. PLoS One. 2016;11: e0151814. doi:10.1371/journal.pone.0151814 Morato RG, Stabach JA, Fleming CH, Calabrese JM, De Paula RC, Ferraz KMPM, et al. Space Use and Movement of a Neotropical Top Predator: The Endangered Jaguar. Stöck M, editor. PLoS One. 2016;11: e0168176. doi:10.1371/journal.pone.0168176 Paviolo A, De Angelo C, Ferraz KMPMB, Morato RG, Martinez Pardo J, Srbek-Araujo AC, et al. A biodiversity hotspot losing its top predator: The challenge of jaguar conservation in the Atlantic Forest of South America. Sci Rep. 2016;6: 37147. doi:10.1038/srep37147 https://open.spotify.com/episode/5qUk82Zas8pNNhi2CwoEKu?si=f0ed2904169f455a https://open.spotify.com/episode/0iKdeK4UUD0T9utUNEwgTu?si=f910b924de3045f8 Dá uma força para manter o DesAbraçando online e com episódios no cronograma contribuindo financeiramente com nosso projeto: O DesAbraçando é um projeto independente e conta com o apoio dos ouvintes para se manter online e pagar a edição de áudio. Se você curte o projeto, considere apoiar financeiramente. Você pode contribuir a partir de R$ 1,00 no www.apoia.se/desabrace Segue a gente lá nas redes sociais: https://www.instagram.com/desabrace/Instagram https://web.facebook.com/desabrace/Facebook https://twitter.com/desabrace Canal no Telegram: https://t.me/desabrace Visite nossa página: https://www.desabrace.com.br Envie suas pedradas: primeirapedra@desabrace.com.br Envie sua resposta para o "Que bicho é esse?": bicho@desabrace.com.br Produção, pauta, apresentação e edição de áudio: Fernando Lima Decupagem de Áudio: Senhor A

Words and Actions
Language and Technology

Words and Actions

Play Episode Listen Later Mar 11, 2022 55:36


Yesterday's sci-fi has become today's reality. Join us as we venture our way into the ever-growing domain of Language Technology in which we discover and discuss current and future developments in speech recognition, automated literary translation, opinion mining and open domain chatbot applications. Not only do we find ourselves having cheeky chats with clever cars and critical conversations with experts,  we also ponder over the pros and cons of Artificial Intelligence and assess our position as linguists (and one alleged Professor of Disco Studies) in view of these developments.     For more information, references and a full transcript please visit wordsandactions.blog In this episode we start our discussion of language and technology with voice recognition. Bernard mentions a general bias towards female voices, as discussed in this paper: Edworthy J., Hellier E., & Rivers J. (2003). The use of male or female voices in warnings systems: a question of acoustics. Noise and Health, 6(21): 39-50.  Pitch range is also important, as demonstrated in the experiment on using different voices for sat navs that Erika mentions:  Niebuhr, O., & Michalsky, J. (2019). Computer-generated speaker charisma and its effects on human actions in a car-navigation system experiment: or how Steve Jobs' tone of voice can take you anywhere. In Misra S. et al. (eds) Computational Science and Its Applications – ICCSA 2019. Lecture Notes in Computer Science, vol. 11620:  375-390. Springer, Cham. https://doi.org/10.1007/978-3-030-24296-1_31  Moving from acoustics to culture, the following paper discusses how male voices are perceived as more authoritative:  Anderson R.C., & Klofstad, C.A. (2012). Preference for leaders with masculine voices holds in the case of feminine leadership roles. PLoS ONE, 7(12): e51216. https://doi.org/10.1371/journal.pone.0051216 It is worth sharing a few more auto-captioning gems in the lectures of Veronika and her colleagues at Lancaster University:  "my grammar is leaving me" →  "my grandma is leading me" “n-sizes” → “incisors” “Hardaker and McGlashan” → “heartache and regression” “institutional” → "it's too slow" (truth!) “masculine” → "mass killer" (bit harsh)   On readability, Bernard mentions an example from accounting, namely the obfuscation hypothesis. The following paper on the topic is considered the first accounting study that uses automated textual analysis with a very large sample to address readability: Li, F. (2008). Annual report readability, current earnings, and earnings persistence. Journal of Accounting & Economics, 45: 221–247. doi:10.1016/j.jacceco.2008.02.003    We then go on to talk about sentiment analysis, which is used to find out about, for example, brand perceptions or patient satisfaction. Here is an example of the latter:   Hopper, A. M., & Uriyo, M. (2015). Using sentiment analysis to review patient satisfaction data located on the internet. Journal of Health Organization and Management, 29(2): 221-233. DOI 10.1108/JHOM-12-2011-0129   In the context of this episode, we want to distinguish between corpus linguistics and computational linguistics. Although language corpora are used to train systems in machine learning, corpus linguists engage in the computer-assisted analysis of large text collections, often combining automated statistical analysis with manual qualitative analysis. A company using such mixed corpus linguistic methods to provide their customers with insights about their products and services is Relative Insight. (We did not receive any funding from them for this episode, but they are a spin-off company that started at Lancaster University.) A critical evaluation of another area of computational linguistics, topic modelling, written by two corpus linguists is:    Brookes, G.,  & McEnery, T. (2018). The utility of topic modelling for discourse studies: A critical evaluation. Discourse Studies, 21(1): 3-21. https://doi.org/10.1177/1461445618814032   (Incidentally, the above paper is also based on data about patient satisfaction.)   The PhD thesis on automatic irony detection that Bernard mentions was written by Cynthia Van Hee and is available here.    The second interview quest is another one of Bernard's colleagues from Ghent University, Orphée De Clercq. Her recent publications include:    De Bruyne, L., De Clercq, O., & Hoste, V. (2021). Annotating affective dimensions in user-generated content. Language Resources and Evaluation, 55(4): 1017-1045. De Clercq, O., De Sutter, G., Loock, R., Cappelle, B., & Plevoets, K. (2021). Uncovering machine translationese using corpus analysis techniques to distinguish between original and machine-translated French. Translation Quarterly, 101: 21-45.   And finally, we talk to Doris Dippold from the University of Surrey in the UK. Her work on chatbots can be found in:  Dippold, D., Lynden, J., Shrubsall, R., & Ingram, R. (2020). A turn to language: How interactional sociolinguistics informs the redesign of prompt: response chatbot turns. Discourse, Context & Media, 37. https://doi.org/10.1016/j.dcm.2020.100432

The Gary Null Show
The Gary Null Show - 03.10.22

The Gary Null Show

Play Episode Listen Later Mar 10, 2022 58:50


COVID-19: Tannic acid targets key stages in the fight against SARS-CoV-2 infection   Natural polyphenol seems to inhibit the activity of three important molecular pathways involved in the SARS-CoV-2 infection Université de Montréal and McGill University, March 9, 2022   Professor Charles Ramassamy and his postdoctoral researcher Mohamed Haddad at  Institut national de la recherche scientifique (INRS), in collaboration with scientists from Université de Montréal, McGill University, and Université du Québec à Montréal (UQAM), believe that tannic acid plays a role in inhibiting three important molecular pathways involved in the SARS-CoV-2 infection. Their work was published recently in the International Journal of Molecular Sciences (IJMS). Using a multidisciplinary approach, the teams showed that tannic acid inhibits the viral protein (RBD) of the British variant of SARS-CoV-2 from binding to its biological target, the ACE2 receptor. This receptor, which is found on the surface of many cells in the body, allows the virus to latch on and infect them. “Tannic acid binds to the RBD protein and prevents it from binding to the ACE2 receptor,” said Professor Ramassamy. He explained that in blocking the viral protein, tannic acid does not alter the physiological functions of ACE2 receptors, which have physiological functions in the body's respiratory, cardiovascular, and renal systems, among others.   (NEXT)   Mindfulness-based cognitive therapy benefits people with depression through promoting self-kindness   University of Exeter, March 9, 2022   New research shows that Mindfulness-Based Cognitive Therapy (MBCT) can help promote self-kindness in people with a history of depression, thereby putting their bodies in a state of safety and relaxation. The research, led by the University of Exeter with collaboration from the universities of Oxford and Magdeburg, indicates that MBCT may help break the cycle of highly critical thoughts and feelings of worthlessness, which often lead people with depression to relapse. Participants treated with MBCT showed a pattern of being kind to themselves, along with body responses of reduced threat response, a state of safety and relaxation that is important for regeneration and healing. Previous research has shown that individuals with recurrent depression benefit particularly from MBCT when they learn to become more compassionate towards themselves. This increased self-compassion has been defined as the ability to be kind to ourselves in stressful times.   (NEXT)   Herbal compound prevents colon cancer in mice   University of South Carolina School of Medicine, March 9, 2022   The active compound in Chinese herbs called emodin (naturally found in rhubarb and Japanese knotweed) can prevent colon cancer in mice, according to researchers at the University of South Carolina School of Medicine. Physiologists conducting this study say this is likely due to emodin's ability to reduce the number of pro-tumor macrophages (a type of immune cell that can promote tumorigenesis). The study is published ahead of print in the American Journal of Physiology-Gastrointestinal and Liver Physiology and has been chosen as an APSselect article for March.   (NEXT)   Resistance exercise may be superior to aerobic exercise for getting better ZZZs   Iowa State University, March 3, 2022    Resistance exercise may be superior to aerobic exercise as a way to get better sleep, and sleep is important for cardiovascular health, according to new preliminary research . “It is increasingly recognized that getting enough sleep, particularly high-quality sleep, is important for health including cardiovascular health. Unfortunately, more than a third of Americans don't get enough sleep on a regular basis,” said study author Angelique Brellenthin, Ph.D.,  “Aerobic activity is often recommended to improve sleep, yet very little is known about the effects of resistance exercise versus aerobic exercise on sleep. For this study, researchers enrolled 386 adults who met the criteria for overweight or obesity, which was a body mass index from 25-40 kg/m². Participants were inactive and had elevated blood pressure, measuring from 120-139 mm Hg systolic (top number) and 80-89 mm Hg diastolic (bottom number). Participants were randomly assigned to a no-exercise group (for comparison) or one of three exercise groups (aerobic only, resistance only, or combined aerobic and resistance) for 12 months. Everyone in the exercise groups participated in supervised 60-minute sessions, three times a week, with the combination exercise group doing 30 minutes of aerobic and 30 minutes of resistance exercise.   (NEXT)   Vitamin A, D and E deficiency linked to repeat colds and flu in Chinese children: Case control study   Harbin Children's Hospital (China), March 8, 2022   Low levels of vitamin A, D and E have been associated with Recurrent Respiratory Tract Infections (RRTI) among children living in Northern China, a new case control study reports. Writing in the journal PLOS One, researchers stated previous studies showed that the incidence of RRTIs among children in northern China ranged from 17.8% to 18.7% . They point out that numerous studies have focused on identifying the association between inadequate concentrations of vitamins A, D, and E and the incidence of RRTIs in Chinese children, but that the results have been contentious. They found that serum levels of vitamins A and E were significantly lower in the RRTI group than the control group. “The conditional logistic regression model and the receiver-operating characteristic curve showed that the insufficiency or deficiency of vitamins A, D, and E was positively correlated with RRTI occurrence (p < 0.05),” they added. “The incidence of insufficiency or deficiency for vitamins A, E, and D was 24.33%, 8.17%, and 19.33% in the control group but increased to 63.00%, 33.83%, and 56.50% in the RRTI group, respectively.” The researchers believe the study demonstrated that lower serum levels of vitamins A, D, and E are associated with RRTIs.  

The Gary Null Show
The Gary Null Show - 03.09.22

The Gary Null Show

Play Episode Listen Later Mar 9, 2022 59:50


Proved the great antitumoral potential of a compound derived from olives   University of Granada (Spain), March 8, 2022   Researchers from the University of Granada (UGR), in collaboration with the universities of Barcelona and Jaen, have brought to light the antitumoral nature of maslinic acid (a compound derived from olives) in Caco-2 p53-deficient colon adenocarcinoma cells in the short term. Maslinic acid (MA) is a natural triterpene found in high concentrations in the waxy skin of olives. The results of this research, recently published in the renowned PloS ONE magazine, show without a doubt how maslinic acid is capable of early inducing the extrinsic cellular death pathway in Caco-2 cells that don't express protein p53 (known by its pro-apoptotic capacity). In previous works, professor Lupiáñez Cara's research team had reported that maslinic acid induces apoptotic cell death via the mitochondrial apoptotic pathway in cancer cell lines.   (NEXT)   Study finds that Nordic diet lowers cholesterol and blood sugar, even if you don't lose weight   University of Copenhagen, March 8, 2022   A healthy Nordic diet can prevent a range of diseases. Until now, the health benefits that researchers had attributed to a Nordic diet primarily focused on weight loss. But in a new study, University of Copenhagen researchers and their Nordic colleagues found clear evidence that a Nordic diet can lower blood sugar and cholesterol levels even without weight loss. In particular, they point to the composition of dietary fats as a possible explanation for the diet's positive effects. Berries, veggies, fish, and whole grains: These are the main ingredients of the Nordic diet concept that for the past decade, has been recognized as extremely healthy, tasty and sustainable. The diet can prevent obesity and reduce the risk of cardiovascular disease, type 2 diabetes, high blood pressure and high cholesterol. Until now, Nordic diet research has primarily been linked to the diet's positive health effect following weight loss. But a new analysis conducted by University of Copenhagen researchers, among others, makes it clear that a Nordic diet has positive health benefits, regardless of whether one loses weight or not.   (NEXT)   Study finds distinct biological ages across individuals' various organs and systems   Beijing Genomics Institute and Lobachevsky State University (Russia), March 8, 2022   It's common to say that someone looks either younger or older than their chronological age, but aging is more than skin deep. Our various organs and systems may have different ages, at least from a biological perspective. In a study published March 8 in the journal Cell Reports, an international team of investigators used biomarkers, statistical modeling, and other techniques to develop tools for measuring the biological ages of various organ systems. Based on their findings, the researchers report that there are multiple "clocks" within the body that vary widely based on factors including genetics and lifestyle in each individual. Most human aging studies have been conducted on older populations and in cohorts with a high incidence of chronic diseases because the aging process in young healthy adults is largely unknown and some studies have suggested that age-related changes could be detected in people as young as their 20s, we decided to focus on this age range."   (NEXT)   Treating heart attacks with a medium chain fatty acid   University of Michigan, March 8, 2022   A medium-chain fatty acid might one day help protect against heart attack injuries. In this publication, we target the interplay between energy metabolism and epigenetics mediated by the medium chain fatty acid 8C." Wang and colleagues were able to protect against heart attack injury in rat models with octanoic acid, an eight carbon (8C) medium chain fatty acid, as well as a few other metabolites. Those fatty acids produced acetyl-CoA, a building block for energy metabolism, which a stressed heart desperately needs. The idea is that a physician would administer this therapy to a person once they arrive at the hospital after having a heart attack, to reduce further injury and improve heart function during recovery, he says.   (NEXT)   Stress damages the movement centers in the brain   University of Bonn (Germany), March 8, 2022   Stress seems to have a negative effect on the learning of movements—at least in mice. This is the conclusion of a recent study at the University of Bonn. According to the study, the neurons of rodents lose some of their contacts with other neurons after stress. The animals also developed motor deficits. The results may be useful for earlier diagnosis and improved therapy of stress-related diseases such as depression. They also document that stress leaves traces in the brain—possibly permanent ones. The study appeared in the journal Translational Psychiatry.Chronically stressed people often show abnormalities in their motor skills, such as poorer fine motor control. The researchers came across a conspicuous feature: after the stressful situation, the neurons studied lost some of their synapses—these are the contacts to other nerve cells. During learning processes, new synapses are usually formed or existing ones are strengthened. Instead, the stressed rodents lost up to 15 percent of their contacts.   (OTHER NEWS)   Lead exposure in last century shrunk IQ scores of half of Americans   Duke University, March 7, 2022   In 1923, lead was first added to gasoline to help keep car engines healthy. However, automotive health came at the great expense of our own well-being. A new study calculates that exposure to car exhaust from leaded gas during childhood stole a collective 824 million IQ points from more than 170 million Americans alive today, about half the population of the United States. The findings suggest that Americans born before 1996 may now be at greater risk for lead-related health problems, such as faster aging of the brain. Leaded gas for cars was banned in the U.S. in 1996, but the researchers say that anyone born before the end of that era, and especially those at the peak of its use in the 1960s and 1970s, had concerningly high lead exposures as children. The team's paper appeared the week of March 7 in the journal Proceedings of the National Academy of Sciences. Lead is able to reach the bloodstream once it's inhaled as dust, or ingested, or consumed in water. In the bloodstream, it's able to pass into the brain through the blood-brain barrier, which is quite good at keeping a lot of toxicants and pathogens out of the brain, but not all of them. One major way lead used to invade bloodstreams was through automotive exhaust.   (NEXT)   Amazon rainforest is losing resilience: New evidence from satellite data analysis   Potsdam Institute for Climate Impact Research (Germany), March 7, 2022   The Amazon rainforest is likely losing resilience, data analysis from high-resolution satellite images suggests. This is due to stress from a combination of logging and burning – the influence of human-caused climate change is not clearly determinable so far, but will likely matter greatly in the future. For about three quarters of the forest, the ability to recover from perturbation has been decreasing since the early 2000s, which the scientists see as a warning sign. The new evidence is derived from advanced statistical analysis of satellite data of changes in vegetation biomass and productivity. “Reduced resilience – the ability to recover from perturbations like droughts or fires – can mean an increased risk of dieback of the Amazon rainforest. The Amazon rainforest is a home to a unique host of biodiversity, strongly influences rainfall all over South America by way of its enormous evapotranspiration, and stores huge amounts of carbon that could be released as greenhouse gases in the case of even partial dieback, in turn contributing to further global warming. This is why the rainforest is of global relevance. The Amazon is considered a potential tipping element in the Earth system and a number of studies revealed its vulnerability.

Authentic Biochemistry
Diabetes VII. Cholangiocarcinomas and the corruption of the biliary system as sequalae of obesity and associated pancreatic exocrine insufficiency of diabetes. Dr Dan Guerra. 3.March.2022. A.B.

Authentic Biochemistry

Play Episode Listen Later Mar 4, 2022 29:48


References Dr Guerra's lecture notes World J Gastroenterol. 2013 Nov 14; 19(42): 7258–7266. Int J Endocrinol. 2015; 2015: 595649. PLoS One. 2017; 12(10): e0186643. BMC Cancer. 2019; 19: 185 --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message Support this podcast: https://anchor.fm/dr-daniel-j-guerra/support

The Gary Null Show
The Gary Null Show - 03.03.22

The Gary Null Show

Play Episode Listen Later Mar 3, 2022 58:15


Spice up your life: Cinnamon's weight loss potential   University of Tokyo Japan, March 2, 2022   The active compound in cinnamon maybe a more tolerable weight loss ingredient than chilli pepper's capsaicin, a small exploratory clinical trial finds. A single ingestion of the active compound cinnamaldehyde increased energy expenditure by nearly four more calories over a 90 minute period compared to placebo. The researchers say cinnamaldehyde may offer a more tolerable thermogenic alternative to compounds like capsaicin found in chilli peppers. Anti-obesity effects? Transient receptor potential (TRP) channels are located throughout the body and mediate sensations such as pain, taste and temperature. TRP channels can be activated by natural compounds such as chilli peppers' capsaicin and previous animal studies have suggested this may impact energy balance and have an 'anti-obesity' effect. Capsaicin can increase metabolism in humans through sensory nerve stimulation. A single ingestion of cinnamaldehyde significantly increased energy expenditure by 3.6 kcal over the 90-minute period of the experiment when compared to placebo. Capsaicin and cinnamaldehyde enhanced postprandial fat oxidation and increased nose temperature until 15 minutes after ingestion. Cinnamaldehyde also increased the cheek and chin temperature, the facial thermography revealed. Heart rate variability analysis did not show any changes to the nervous system.   (NEXT)   Exposure to great outdoors boosted mental health during pandemic    University of Colorado, March 2, 2022   People exposed to more green space during the first year of the COVID-19 pandemic reported significantly less depression and anxiety, according to new University of Colorado Boulder research published  in the journal PLOS One. The study also found that, at a time when mental health problems soared due to financial woes, supply shortages and nonstop news coverage of the virus, people sought solace in the great outdoors, with one-third spending more time there than they did pre-COVID. “This research shows how critical it is to keep parks and green spaces open in times of crisis. “It also shows that, as a public health measure, more effort should be made to put in green spaces and make them accessible.” The study adds to a growing body of evidence suggesting that green space can have a measurable impact on health.   (NEXT)   National study examines link between accountability to god, psychological well-being   Baylor University, March 2, 2022   Religious believers who embrace accountability to God (or another transcendent guide for life) experience higher levels of three of the four variables of psychological well-being – mattering to others, dignity and meaning in their lives, though not happiness – according to a study from researchers with Baylor University, Westmont College and Hope College. The study also found that this relationship is stronger among those who pray more often, suggesting that accountability coupled with communication may be a powerful combination for well-being. The study, Perceptions of Accountability to God and Psychological Well-Being Among US Adults, appears in Journal of Religion and Health and relies on data from the 2017 Baylor Religion Survey, a national survey of American religious beliefs, values and behaviors.   (NEXT)   Regular chocolate intake linked to enhanced cognition in cohort study   University of South Australia and University of Maine, March 2, 2022   Habitual chocolate consumption has correlation with better cognitive functioning, according to analyses of 968 people living in New York A study due for publication in the journal Appetite by researchers at the University of South Australia, the University of Maine and the Luxembourg Institute of Health (L.I.H.) examined the chocolate eating habits and cognitive performance of participants and assessed the eating habits of 968 people aged 23–98 years for 25 years.   (NEXT)   Acupuncture improves outcomes in carpal tunnel syndrome in part by remapping the brain   Massachusetts General Hospital, March 2, 2022   In a study reported in the journal Brain, a team of investigators based at Massachusetts General Hospital (MGH) sheds new light on exploring acupuncture for chronic pain disorders Researchers performed a sham-controlled acupuncture neuroimaging study of carpal tunnel syndrome (CTS), a neuropathic pain disorder. Few chronic pain disorders have established biomarkers or measureable treatment outcomes. However, in CTS measurements taken at the wrist of the speed at which signals are transmitted along the median nerve are a well known and accepted biomarker.   (OTHER NEWS - JUST ONE IF NECESSARY BEFORE MCGOVERN)   Analysis: Nuclear Disaster in Ukraine Could Make Swaths of Europe 'Uninhabitable for Decades'   Russia's assault on Ukraine risks nuclear devastation "far worse even than the Fukushima Daiichi catastrophe of 2011," Greenpeace warns.   Common Dreams. March 2, 2022   The international environmental group Greenpeace warned Wednesday that Russia's intensifying assault is placing Ukraine's nuclear power facilities under serious threat, risking devastation "far worse even than the Fukushima Daiichi catastrophe of 2011." In a 12-page analysis, Greenpeace details the unique hazards posed by Russia's war on Ukraine, which maintains 15 nuclear power reactors and is home to the largest nuclear energy complex in Europe. That facility, known as the Zaporizhzhia Nuclear Power Plant, is currently surrounded by Russian troops looking to force their way through a makeshift blockade erected Wednesday by ordinary Ukrainians. Greenpeace's new brief argues that the Zaporizhzhia plant is especially vulnerable to an accident or attack stemming from Russia's invasion,. Greenpeace raises particular concern over the complex's susceptibility to electrical power outages, its storage of spent nuclear fuel, and risks posed by flooding given the facility's close proximity to the massive Dnipro river system. Severe damage to the plant, the group warns, could "render vast areas of the European continent, including Russia, uninhabitable for decades." "For the first time in history, a major war is being waged in a country with multiple nuclear reactors and thousands of tons of highly radioactive spent fuel," he continued. "The war in southern Ukraine around Zaporizhzhia puts them all at heightened risk of a severe accident."   (GUEST) GUEST - RAY MCGOVERN

Neuroscience: Amateur Hour
Episode 10: The Neuroscience of ADHD

Neuroscience: Amateur Hour

Play Episode Listen Later Feb 24, 2022 18:03


ADHD -  attention deficit hyperactivity disorder - is a condition characterized by differences in brain development and brain activity that affect attention, the ability to sit still, and impulse control. It affects millions of children and adults and has far-reaching effects on the lives and well-being of these individuals. And yet we still don't know what going on!Is it genetic? Is it environmental? Come and listen to learn a little bit more about the neuroscience of ADHD and what's going on in your head. Please rate, review, and subscribe and if you have any questions, comments, concerns, queries, or complaints, please email me at neuroscienceamateurhour@gmail.com or DM me at NeuroscienceAmateurHour on Instagram.Citations and relevant pictures below:Demontis D, Walters RK, Martin J, et al. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nature Genetics. 2018;51(1):63-75. doi:10.1038/s41588-018-0269-7Faraone SV, Larsson H. Genetics of attention deficit hyperactivity disorder. Molecular Psychiatry. 2018;24(4). doi:10.1038/s41380-018-0070-0Froehlich TE, Anixt JS, Loe IM, Chirdkiatgumchai V, Kuan L, Gilman RC. Update on Environmental Risk Factors for Attention-Deficit/Hyperactivity Disorder. Current Psychiatry Reports. 2011;13(5):333-344. doi:10.1007/s11920-011-0221-3Oscar Berman M, Blum K, Chen TJ, et al. Attention-deficit-hyperactivity disorder and reward deficiency syndrome. Neuropsychiatric Disease and Treatment. 2008;4(5):893. doi:10.2147/ndt.s2627Quist JF, Barr CL, Schachar R, et al. The serotonin 5-HT1B receptor gene and attention deficit hyperactivity disorder. Molecular Psychiatry. 2003;8(1):98-102. doi:10.1038/sj.mp.4001244Zulauf CA, Sprich SE, Safren SA, Wilens TE. The Complicated Relationship Between Attention Deficit/Hyperactivity Disorder and Substance Use Disorders. Current Psychiatry Reports. 2014;16(3). doi:10.1007/s11920-013-0436-6Tomasi D, Volkow ND, Wang R, et al. Dopamine Transporters in Striatum Correlate with Deactivation in the Default Mode Network during Visuospatial Attention. Rustichini A, ed. PLoS ONE. 2009;4(6):e6102. doi:10.1371/journal.pone.0006102Ritalin Poses Cognitive Risks to Those Without ADHD. Pharmacy Times. https://www.pharmacytimes.com/view/ritalin-poses-cognitive-risks-to-those-without-adhdSupport the show (https://www.patreon.com/neuroscienceamateurhour)

The Gary Null Show
The Gary Null Show - 02.22.22

The Gary Null Show

Play Episode Listen Later Feb 22, 2022 55:55


Depression linked to reduced arginine levels University of Eastern Finland, February 20, 2022 People suffering from major depressive disorder, MDD, have reduced arginine levels, a new study from the University of Eastern Finland shows. Arginine is an amino acid which the body uses to produce, e.g., nitric oxide. Nitric oxide, in turn, is a nervous system and immune defence mediator, and it also plays a role in vascular regulation. The global arginine bioavailability ratio, GABR, is an indicator of the body's arginine levels, and the ratio has previously been used to measure the body's capacity to produce nitric oxide. Reduced arginine bioavailability is also known to be an independent risk factor of cardiovascular diseases. (NEXT) Vitamin D supplementation associated with improvement in mood, desire in women Medical University of Silesia (Poland), February 19 2022  A study reported in Endokrynologia Polska resulted in improvement in female sexual desire, orgasm and satisfaction, as well as mood, after supplementation with vitamin D. Based on researchers Robert Krysiak and colleagues' previous finding of an association between deficient vitamin D levels and abnormal female sexual function, a trial that examined the effects of six months of oral vitamin D supplementation was conducted among 47 women with deficient or insufficient plasma vitamin D levels. Women with vitamin D deficiency, defined as plasma 25-hydroxyvitamin D levels that were lower than 2 nanograms per milliliter (ng/mL), were given 4,000 international units (IU) vitamin D per day, and participants with insufficient levels of 20-30 ng/mL were given 2,000 IU daily or no vitamin D. Questionnaires that evaluated female sexual function and depressive symptoms were completed before and after the treatment period. Supplementation with vitamin D was associated with improved sexual desire in both deficient and insufficient women. Among participants with vitamin D deficiency, vitamin D improved total sexual function scores and scores for sexual satisfaction and orgasm, while decreasing total depression scores. (NEXT) Midwifery linked to better birth outcomes in state-by-state report cards Oregon State University, February 22, 2022  Midwife-friendly laws and regulations tend to coincide with lower rates of premature births, cesarean deliveries and newborn deaths, according to a new U.S.-wide “report card” that ranks all 50 states on the quality of their maternity care. The first-of-its-kind study found a strong connection between the role of midwives in the health care system – what the researchers call “midwifery integration” – and birth outcomes. States with high midwifery integration, like Washington and Oregon, generally had better results, while states with the least integration, primarily in the Midwest and South, tended to do worse. The findings were published in the journal PLOS ONE. About 10 percent of U.S. births involve midwives, far behind other industrialized countries, where midwives participate in half or more of all deliveries. Each state has its own laws and regulations on midwives' credentialing, their ability to provide services at a client's home or at birth centers, their authority to prescribe medication and the degree to which they are reimbursed by Medicaid. (NEXT) Microbiome changes could underlie nicotinamide riboside's ability to protect against weight gain Medical College of Wisconsin, February 21 2022. The January/February 2022 issue of the journal mSystems reported how the vitamin B3 derivative nicotinamide riboside (NR) impacts the gut microbiome and protects against weight gain. NR is a precursor of NAD+, a coenzyme found in all cells that aids in the production of energy. “Gut bacteria produce vitamin B3 in the colon and are capable of salvaging and metabolizing vitamin B3 and its derivatives,” wrote Valery V. Lozada-Fernández of the Medical College of Wisconsin in Milwaukee and colleagues. “However, it is unknown how dietary supplementation of NR alters the microbiome and if those alterations contribute to deflection of weight gain.” Mice were given diets that were high in fat with or without the addition of NR. NR supplementation resulted in less body mass gain, lower fasting glucose levels and differences in gut microbes, including a greater number of bacteria that produce butyrate. (NEXT) How sound waves could help regrow bones RMIT University (Netherlands), February 22,2022 Researchers have used sound waves to turn stem cells into bone cells, in a tissue engineering advance that could one day help patients regrow bone lost to cancer or degenerative disease. The innovative stem cell treatment from researchers at RMIT University offers a smart way forward for overcoming some of the field's biggest challenges, through the precision power of high-frequency soundwaves. Tissue engineering is an emerging field that aims to rebuild bone and muscle by harnessing the human body's natural ability to heal itself. Additionally, the few clinical trials attempting to regrow bone have largely used stem cells extracted from a patient's bone marrow—a highly painful procedure. In a new study published in the journal Small, the RMIT research team showed stem cells treated with high-frequency sound waves turned into bone cells quickly and efficiently. (Videos) 1. Justin Trudeau's China dictatorship gaffe (1:30) (start at :25) 2. Edward Dowd Clip (5:50) 3. Banishment From The Financial System The War On Dissent (11:51) 4. “OH MY GOD! Six Fatal Mistakes in Two Weeks”Jordan Peterson 5. Communism Has Arrived   6. Jonathan Haidt & Yuval Noah Harari: Adapting to Change in an Accelerating World (15:00 to 30:00)   (OTHER NEWS) Wokeism Is a Cruel and Dangerous Cult Wokeism's natural logic is to destroy the lives of people of both genders, of all races, and—if need be—of those of every age, all to leverage an otherwise unworkable ideological agenda. Victor Davis Hanson (Stanford University) Wokeism has been described by its critics as the omnipresent use of race—and to a lesser extent, gender—to replace meritocracy and thus ensure equality of result. What follows from implementing that ideology are reparatory actions to reward those of the present by atoning for the injustices done to others in the past. Some see it as an update of 1960s cultural Marxism fads. Others scoff that it is just a return to 1980s-style political correctness. Still more see it as the logical successor to 1990s-type race, class, and gender obsessions—albeit with a shriller and more dangerous Jacobin, Soviet, and Maoist twist. Wokeism's hysteria also invites comparisons to the Salem witch trials and McCarthyism. But few have described wokeism as the cruel creed that it is. Wokeism's natural logic is to destroy the lives of people of both genders, of all races, and—if need be—those of every age, all to leverage an otherwise unworkable ideological agenda. It is nihilist and destroys everything it touches. It tears apart foes and friends alike, whether by fueling media-driven hatred of Donald Trump or faux-deification of the disaster that is now Joe Biden. Woke's Victims Defunding law enforcement and defaming police resulted in record numbers of murders in 12 U.S. cities. A wave of violent crime is even hitting America's suburbs. Without much fear of arrest, indictment, conviction, and incarceration, emboldened violent career criminals for the past year have robbed, assaulted, and killed the innocent with impunity. The victims at the bus stop, the subway, or in the furniture store do not seem to warrant media or progressive attention, much less sympathy. They are the ignored—the unnamed, and the forgotten collateral damage from the grand experiment of redefining crime as a social construct. The guilty are the elite academics, activists, and billionaires like George Soros who are untouched by what they birthed. We have all seen videos of the vast expanse of flotsam and jetsam strewn by train thieves along the Union Pacific tracks in Los Angeles. Yet the Wild West mess is still more than just the concrete manifestations of Los Angeles County district attorney George Gascón's unhinged efforts to excuse criminals from legal consequences. The packages thrown along the ground by thugs and gangsters represent, among other things, lost COVID-19 test results of the ill. Presumably, they unknowingly are waiting still by the window for the delivery of results that never arrive. The package in the dirt was, perhaps, a key tractor part eagerly awaited, in vain, by the broke farmer in the Central Valley. The mess included the life-saving medicines shipped to the sick that disappeared. And our elected leaders did what in response? Governor Gavin Newsom apologized for using the insensitive word “gangs” to describe those who plunder, loot, and trash railcars. Always In Search of Targets It is a cruel thing to indoctrinate children with the lie that they are innately guilty of oppression due to their skin color. One accurate definition of racism is collective ill-treatment of an individual due to his innate appearance—on the pretext that such bias is deserved, given the target is deemed mentally, spiritually, or morally inferior because of said traits. But that, in a nutshell, is the essence of critical race theory: the destruction of all human traits and unique characteristics, as demonized individuals are reduced to stereotyped, faceless members of a collective. The Forgotten Broken Eggs of the Woke Omelet Equity in our Orwellian world is not equality, but payback. Again, it is the idea of making the current generation pay for the supposed sins of the long dead of centuries past. Aside from the destruction of merit by the substitution of racial criteria, millions from a discarded generation will have doors slammed on their careers—simply because of the color of their skin. And they will never forget that. The woke do not even make the effort to admit that class matters as much as, or more than, race. By doing so, they doom millions of poor white and Asian students, who managed in poverty to achieve excellent grades and test scores, from being admitted to top-tier schools. Their actual achievement, despite their absence of wealthy, college-educated, or well-connected parents, means little. Once a morally bankrupt society—for naïve, utopian, or ignoble reasons—begins to calibrate graduation ceremonies, dorm space, roommate selection, achievement, and grading standards based on race, then it not only will lose its standard of living, but it will deserve to. And it may have a future date with the violence of Rwanda, Iraq, or the Balkans. Power, Not “Equity,” Is the Creed In sum, wokeness is not about kindness, equality, fairness, or morality. It is the power agenda of the elite of all races. For differing reasons, they rig the game in their own interests, without a care about who suffers. Rich white people assume that they possess the money, the influence, the networking skills, and the connections to navigate around the very exclusionary rules they make for others. For them, there are seldom costs. But they win apparent psychological gain at feeling spiritually superior while driving a Range Rover. They get high on the sense of power they wield to engineer the lives of millions deemed less important than they. And to the degree they feel guilty about their own monopoly of wealth and leisure, such transient superficial remorse is alleviated by abstract caring for the “other.” If they can ensure that 50 percent of TV commercials highlight African Americans, then they worry little about the nation's existential crisis of 800 blacks murdered in Chicago last year. And no such television execs have a clue—or likely a concern—about how to stop it. The woke take out a medieval contract that all their material indulgences can be balanced by virtue-signaling caring for the less fortunate—although always at someone else's expense. Woke = Wealthy Careerists And for the millions of the affluent, elite nonwhite? The resurgence of racial obsessions conveniently destroys the old idea of class, even though now it is the far more precise calibration of inequality. For all the woke talk about “constructs” of gender, race is somehow alone exempted and declared innate, definable, and immutable. One's appearance becomes the permanent victimized refuge—even of NBA multibillionaires and billionaire rappers alike. A Ward Churchill or Elizabeth Warren can desperately seek to leverage a career in becoming Native American, apparently as if they were almost trapped in their own white bodies. Yet they can still not manage to construct such assumed identities in the manner of Bruce/Caitlyn Jenner. If race is now the sole immutable barometer of who is a victim, who a victimizer, then LeBron James, Jay-Z, Kayne West, Chris Rock, Michelle Obama, and Oprah Winfrey are always to be among the eternally oppressed. The enormous influence, power, status, and wealth they wield never negates their victimhood, despite a nation three generations into affirmative action. In the immoral calculus of woke, the poor white or Southeast Asian offspring of poorly paid high-school dropouts constitute “the privileged.” And a multimillionaire racist like the TV anchorwoman Joy Reid claims to be the perpetual victim, not the inner-city African American retiree who in 2021 has lost local police protection. No wonder the woke elite and the affluent leftists fixate on race, given they are now the ruling class. Otherwise, their own privilege would be the obvious target of the once-beloved “Revolution.” So, they fear that by their own prior left-wing standards, they too could end up on the wrong side of their moral Maginot Line. Wokeism's obsessions with ferreting out “white privilege” are a way for rich people to head off (so to speak) the fate of Marie Antoinette. Totalitarian Wokeism A final note. We know wokeism is both contrary to human nature and antithetical to democracy and constitutional government. Without public support, it has instead embraced an entire array of cruel, Soviet, and Maoist means to achieve its own self-interested ends. Woke talk about “racists” eerily emulates Soviet boilerplate about “counterrevolutionaries.” Today's wokeist spouts things that could come right out of the mouth of the novelist Boris Pasternak's character Army Commissar Strelnikov, or Mao's Little Red Book concerning “suppression of counterrevolutionaries.” No wonder the woke, so-called “humanists” are the first to resort to Trotskyization and iconoclasm. They are masters of censoring, blacklisting, scapegoating, deplatforming, ritual humiliation, doxxing, cancel-culture, ostracism, and disbarring. Wokeism's logic is the eternal one of the bully Jacobin with his guillotine lists of the revolutionary unpure, the 19th-century lynch mob storming the frontier jail, the Red Guards hounding the counterrevolutionary, and the forced mental hospitalizations of the Soviet Union. But above all, wokeism is a cruel cult—created by and for the careerist benefit of the privileged.

Curiosity Daily
Back Pain in Space, Cats' Mental Maps, Diamond Davemaoite

Curiosity Daily

Play Episode Listen Later Feb 16, 2022 18:04


Learn about back pain from space; how cats track their owners; and what davemaoite tells us about Earth's lower mantle.Space travel causes back pain, and doctors need to find a fix by Cameron DukeBack pain common among astronauts offers treatment insights for the earth-bound. (2021, October 21). EurekAlert! https://www.eurekalert.org/news-releases/932251Penchev, R., Scheuring, R. A., Soto, A. T., Miletich, D. M., Kerstman, E., & Cohen, S. P. (2021). Back Pain in Outer Space. Anesthesiology, 135(3), 384–395. https://doi.org/10.1097/aln.0000000000003812Cats track their owners with mental maps by Cameron DukeTakagi, S., Chijiiwa, H., Arahori, M., Saito, A., Fujita, K., & Kuroshima, H. (2021). Socio-spatial cognition in cats: Mentally mapping owner's location from voice. PLOS ONE, 16(11), e0257611. https://doi.org/10.1371/journal.pone.0257611Weisberger, M. (2021, November 11). You can't hide from your cat, so don't even try. Livescience.com; Live Science. https://www.livescience.com/cats-track-ownersTaboo Science Podcast - The podcast that answers the questions you're not allowed to ask. (2020). Tabooscience.show. https://www.tabooscience.show/Scientists found a once-theoretical mineral inside a diamond that tells us more about the Earth's lower mantle by Grant Currin A mineral found in a diamond's flaws contains the source of some of Earth's heat. (2021, November 11). Science News. https://www.sciencenews.org/article/mineral-diamond-davemaoite-earth-mantle-heatKoumoundouros, T. (2021). Elusive Crystal Predicted Decades Ago Found Trapped in a Diamond From The Deep Earth. ScienceAlert. https://www.sciencealert.com/a-diamond-caught-and-preserved-the-deepest-rare-earth-mineral-science-has-ever-examinedPiesing, M. (2019). The deepest hole we have ever dug. Bbc.com. https://www.bbc.com/future/article/20190503-the-deepest-hole-we-have-ever-dugTschauner, O., Huang, S., Yang, S., Humayun, M., Liu, W., Gilbert Corder, S. N., Bechtel, H. A., Tischler, J., & Rossman, G. R. (2021). Discovery of davemaoite, CaSiO 3 -perovskite, as a mineral from the lower mantle. Science, 374(6569), 891–894. https://doi.org/10.1126/science.abl8568Learn more about host Cody Gough on Giveo and at https://academicpodcasts.com. Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers.

The Gary Null Show
The Gary Null Show - 02.15.22

The Gary Null Show

Play Episode Listen Later Feb 15, 2022 55:42


Alpha-lipoic acid supplementation associated with improved lipid levels   Tabriz University of Medical Sciences (Iran), February 14 2022.    Findings from a systematic review and meta-analysis published in the International Journal for Vitamin and Nutrition Research indicated that supplementing with alpha-lipoic acid was associated with improvements in total cholesterol, low-density lipoprotein (LDL) cholesterol and triglycerides. Researchers at Tabriz university of Medical Sciences in Iran selected 12 randomized, placebo-controlled trials that evaluated the association between supplementing with alpha-lipoic acid and lipid levels among a total of 548 participants.  Analysis of all 12 studies (which included data concerning triglycerides) found a significant reduction in triglycerides in association with alpha-lipoic acid. Dose-response analysis found a nonlinear relationship of LDL cholesterol and triglyceride levels with alpha-lipoic acid dosage that was dependent upon the duration of treatment.   (NEXT)   Positive attitudes about aging reduce risk of dementia in older adults   Yale University, February 7, 2022   Research has shown that older persons who have acquired positive beliefs about old age from their surrounding culture are less likely to develop dementia. This protective effect was found for all participants, as well as among those carrying a gene that puts them at higher risk of developing dementia, a new study led by the Yale School of Public Health has found. Published in the journal PLOS ONE, the study reports that older persons with positive age beliefs who carry one of the strongest risk factors for developing dementia—the ε4 variant of the APOE gene —were nearly 50% less likely to develop the disease than their peers who held negative age beliefs.   (NEXT)   Study: Running helps brain stave off effects of chronic stress   Exercise protects vital memory and learning functions Brigham Young University, February 14, 2022   Most people agree that getting a little exercise helps when dealing with stress. A new BYU study discovers exercise -- particularly running -- while under stress also helps protect your memory. The study, newly published in the journal of Neurobiology of Learning and Memory, finds that running mitigates the negative impacts chronic stress has on the hippocampus, the part of the brain responsible for learning and memory. "Exercise is a simple and cost-effective way to eliminate the negative impacts on memory of chronic stress," said study lead author Jeff Edwards, associate professor of physiology and developmental biology at BYU. Inside the hippocampus, memory formation and recall occur optimally when the synapses or connections between neurons are strengthened over time. That process of synaptic strengthening is called long-term potentiation (LTP). Chronic or prolonged stress weakens the synapses, which decreases LTP and ultimately impacts memory. Edwards' study found that when exercise co-occurs with stress, LTP levels are not decreased, but remain normal.   (NEXT)   Extra Virgin Olive Oil: Why It's Healthier Than Other Cooking Oils   University of Hertfordshire (UK), February 14, 2022   Numerous studies have shown that consuming olive oil – in particular extra virgin olive oil (EVOO) – can have many different benefits for our health. For example, the Spanish PREDIMED study (the largest randomised control trial ever conducted on the Mediterranean diet) showed that women who ate a Mediterranean diet supplemented with extra virgin olive oil had a 62% lower risk of breast cancer compared to women who were advised to eat a low-fat diet. Experts who have since examined multiple scientific studies looking at the Mediterranean diet and its effect on chronic diseases conclude that a primary reason the diet protects against breast cancer is because of EVOO. There's also evidence that EVOO may protect against type 2 diabetes and possibly even Alzheimer's disease. Alongside its fat, EVOO contains many natural substances, such as polyphenols. Polyphenols occur naturally in plants, and have been linked to many health benefits, such as reducing the risk of cardiovascular disease and cognitive disorders.   (OTHER NEWS)   EXCLUSIVE: Embalmer reveals 93% of cases died from the vaccine   Anna Foster is an embalmer with 11 years of experience in Carrollton, MO. She reveals that 93% of her last 30 cases died due to clots from the COVID vaccine.   Steve Kirsch, February 14, 2022   Anna Foster is an embalmer with 11 years of experience in Carrollton, MO. She speaks out for the first time The big news is that she found the unusual clots in 93% of the last 30 people who she embalmed. This is significant because she isn't selective about who she embalms. Not all embalmers will see a 93% clot rate. Richard Hirschman only sees these clots in 65% of his cases. Either way, we have identified what is the #1 cause of death in America today; a killer that is much bigger than COVID. This is a massive health issue since it is killing a huge number of people. Her embalmer friends have noticed it as well and have never seen it before in their careers. The clots are only associated with people who have been vaccinated. They were only observed after the vaccines rolled out. The clots are life threatening and are almost certainly the root cause of death in all of these cases. When 93% of people who die are killed by a single cause, this merits immediate investigation by the CDC as to the cause. However, I am certain that the CDC and all legacy media will continue to ignore this story.   (NEXT)   Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021   Centers for Disease Control and Prevention, Emory University, Vanderbilt University, Boston Medical Center, Duke University, US Food and Drug Administration   Journal of American Medical Association, February 2022   Question  What is the risk of myocarditis after mRNA-based COVID-19 vaccination in the US? Findings  In this descriptive study of 1626 cases of myocarditis in a national passive reporting system, the crude reporting rates within 7 days after vaccination exceeded the expected rates across multiple age and sex strata. The rates of myocarditis cases were highest after the second vaccination dose in adolescent males aged 12 to 15 years ), in adolescent males aged 16 to 17 years , and in young men aged 18 to 24 years . Results  Among 192 405 448 persons receiving a total of 354 100 845 mRNA-based COVID-19 vaccines during the study period, there were 1991 reports of myocarditis to VAERS and 1626 of these reports met the case definition of myocarditis. Of those with myocarditis, the median age was 21 years (IQR, 16-31 years) and the median time to symptom onset was 2 days (IQR, 1-3 days). Males comprised 82% of the myocarditis cases for whom sex was reported. The crude reporting rates for cases of myocarditis within 7 days after COVID-19 vaccination exceeded the expected rates of myocarditis across multiple age and sex strata. The rates of myocarditis were highest after the second vaccination dose in adolescent males aged 12 to 15 years (70.7 per million doses of the BNT162b2 vaccine), in adolescent males aged 16 to 17 years (105.9 per million doses of the BNT162b2 vaccine), and in young men aged 18 to 24 years (52.4 and 56.3 per million doses of the BNT162b2 vaccine and the mRNA-1273 vaccine, respectively). There were 826 cases of myocarditis among those younger than 30 years of age who had detailed clinical information available; of these cases, 792 of 809 (98%) had elevated troponin levels, 569 of 794 (72%) had abnormal electrocardiogram results, and 223 of 312 (72%) had abnormal cardiac magnetic resonance imaging results. Approximately 96% of persons (784/813) were hospitalized and 87% (577/661) of these had resolution of presenting symptoms by hospital discharge. The most common treatment was nonsteroidal anti-inflammatory drugs (589/676; 87%). Conclusions and Relevance  Based on passive surveillance reporting in the US, the risk of myocarditis after receiving mRNA-based COVID-19 vaccines was increased across multiple age and sex strata and was highest after the second vaccination dose in adolescent males and young men. This risk should be considered in the context of the benefits of COVID-19 vaccination.

Surfing the Nash Tsunami
S3-E10.2 - What Does the SUNN Study Say About NASH Prevalence?

Surfing the Nash Tsunami

Play Episode Listen Later Feb 12, 2022 12:40


Episode 10 dives into recent NAFLD and NASH Prevalence studies in the US, UK and Germany and explores what this can tell us about who to screen for NAFLD and NASH, when to screen first and how often to screen after that. This conversation focuses on the paper Screening for undiagnosed NAFLD and NASH: A population-based risk factor assessment using Vibration-Controlled Transient Elastography (VCTE), which was published last November in the refereed journal PLOS ONE.Lead author Wayne Eskridge describes the study and presents key findings. In this conversation, two of the striking points he raises about the study are: (1) that relatively high percentages of study participants, volunteers with no previous history of liver disease, exhibited different levels of liver fat and even disease; and (2) that many of these were patients in their 40s as compared to the 50s and 60s where we more conventionally think about disease. After the group shared some concepts and numbers, participants agreed that the number of adults exhibiting some level of fatty liver with an accompanying metabolic challenge is 3 in 8.

Training Ohne Limit
(#76) Nie wieder Knieschmerzen

Training Ohne Limit

Play Episode Listen Later Feb 7, 2022 49:22


Knieschmerzen hatte eigentlich jeder schon einmal, aber neben akuten Sportverletzungen gibt es auch unspezifische Beschwerden. Dafür haben wir heute 3 große Themenbereiche mitgebracht, die wir mit euch zusammen besprechen. Viel Spaß! 00:50 Unspezifische Kniebeschwerden 05:49 Patella-Femorale Schmerzen (PFS) 08:48 Knie-Arthroskopie 14:46 Ist eine operative Therapie sinnvoll? 17:07 Ursachen und Risikofaktoren 19:00 Vastus Medialis und Patella-Maltracking 25:01 Patella-Tendinopathien 28:45 Aufbau Gelenkknorpel 33:40 Knorpeltraining 35:16 Arthrose Entstehungsmechanismus 39:26 Untersuchung Kniegelenk 44:38 Rehabilitation von unspezifischen Kniebeschwerden 47:57 Zusammenfassung ---------------------------------------------- Unsere Website: www.trainingohnelimit.de ---------------------------------------------- Wenn euch die Folge gefallen hat, dann teilt sie mit euren Freunden. Abonniert uns bei Spotify und Apple Podcast, damit ihr keine Folge verpasst. Wir hören uns wieder am nächsten Montag. Startet gut in die neue Woche! Instagram TOL: https://www.instagram.com/trainingohnelimit Instagram Silvan: https://www.instagram.com/silvanschlegelpt Instagram Hendrik: https://www.instagram.com/hendrik_senf ---------------------------------------------- Literaturnachweise: Freddolini, M., Placella, G., Gervasi, G. L., Morello, S., & Cerulli, G. (2017). Quadriceps muscles activity during gait: comparison between PFPS subjects and healthy control. MUSCULOSKELETAL SURGERY, 101(2), 181–187. Vincent, T. L., & Wann, A. K. T. (2018). Mechanoadaptation: articular cartilage through thick and thin. The Journal of Physiology. Smith, B. E., Selfe, J., Thacker, D., Hendrick, P., Bateman, M., Moffatt, F., … Logan, P. (2018). Incidence and prevalence of patellofemoral pain: A systematic review and meta-analysis. PLOS ONE, 13(1), e0190892.

The Gary Null Show
The Gary Null Show - 02.02.22

The Gary Null Show

Play Episode Listen Later Feb 2, 2022 60:18


Meta-analysis affirms association between omega-3 fatty acid intake and lowered inflammation   Zhejiang University (China), February 1 2022   A review and meta-analysis published in the journal PLOS One adds evidence to a reduction in pro-inflammatory eicosanoid levels in association with supplementation with marine-derived omega-3 polyunsaturated fatty acids (PUFAs) by adults. Several arachidonic acid-derived eicosanoids exert their significant influence on the inflammatory response. Prostaglandin E2 (PGE2) is involved in the classic signs of inflammation and possesses both proinflammatory and anti-inflammatory actions; thromboxane A2 (TXA2) (precursor of TXB2), formed by platelets, macrophages and polymorphonuclear leukocytes, can induce vasoconstriction and promotes aggregation of platelets as well as adhesiveness of polymorphonuclear nutrophils; leukotriene B4 (LTB4) can not only increase vascular permeability and enhance local blood flow by stimulating neutrophil secretion, but also stimulate other inflammatory substances.   (NEXT) Lifestyle more likely to affect a child's BMI than the weight of their mother   University of Bristol and Imperial College London, February 1, 2022   Researchers from the University of Bristol and Imperial College London have found that a high Body Mass Index (BMI) of a mother before and during pregnancy is not a major cause of high BMI in their offspring—indicating that childhood and teen obesity is more likely to be a result of lifestyle factors. It is known that greater maternal BMI before or during pregnancy is associated with a higher BMI in children, however the extent to which the mother's weight causes obesity in childhood, or whether this is caused by environmental and lifestyle factors post conception and birth is unclear.   (NEXT) Iron accumulation linked with age-related cognitive decline   Northwestern University, February 1, 2022   Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife This mechanism may explain some age-related cognitive decline and contribute to neurodegenerative diseases such as Parkinson's and Alzheimer's disease. "There is tight regulation of iron homeostasis in the brain, but it appears that this regulation is disrupted as we age," said Ardehali, who is also director of the Center for Molecular Cardiology at the Feinberg Cardiovascular and Renal Research Institute. "There are studies planning to use iron chelators in coronary artery disease and exploring these in the brain and aging is the next step."   (NEXT) Modern diet destroys gut health and causes irreversible damage for generations   Stanford University School of Medicine, February 1, 2022   More Americans than ever are struggling with gut health issues. And, it's no wonder, thanks to the typical American's diet, loaded with processed, low fiber foods, chemicals and denatured ingredients. Some of the symptoms of compromised gut health include constipation, too much (or too little) intestinal gas, diarrhea, chronic bad breath, hormonal issues, menstrual problems, allergies and vitamin deficiencies, just to name a few. Poor gut health will lead to serious digestive issues, autoimmune conditions and even cancer. A study conducted by the Stanford University School of Medicine showed that the typical American diet consisting of mostly low fiber foods produces a range of internal deficiencies. Even worse, these deficiencies tend to get passed down to future generations. After four generations in this study, the losses were shown to be irreversible.   (OTHER NEWS) Why I'm leaving the cult of wokeness   Africa Brooke. 07 Jan 2021   If there's one thing I'm NOT afraid of, it's being 'cancelled'. If being cancelled means me living in integrity as a human being who thinks for themselves, CANCEL ME TODAY! I repeat; I am not afraid.What I'm truly afraid of is existing in a world that forces me to submit to an ideology without question, otherwise I'm to be shamed (or pressured to shame myself) and cast out of the community. A world that tells me that because I inhabit a black body; I will forever be oppressed and at the mercy of some omnipresent monster called 'whiteness'. That because of the colour of my skin; I am a victim of an inherently racist system by default - and me rejecting the narrative of oppression means that I am in fact, in denial. How empowering! *You know, as someone that comes from Zimbabwe, a country where the general population is truly oppressed, it perplexes me that oppression is now being worn as an identity piece in most parts of the West, especially by those who claim to be 'progressive'* What I'm truly afraid of is existing in a world that forces me to consider the colour of my skin and my gender (and that of others) at every fucking turn, instead of living by Martin Luther King's teachings and prioritising the content of mine and other people's character. I dread the prospect of a world where context, nuance, critical thinking, meritocracy, mathematics, science, and rationality are considered tools of 'white supremacy', and the rule is that you're not allowed to question or argue this senseless statement - especially if you're white. A world that is conditioning you and I to believe that we will always be trapped in some weird hierarchy because of our race, our genitals, our physical abilities, our neurodiversity, our sexuality, and our politics. And that if we do not agree on every single thing, it's a sign that we are interacting with an enemy - or at the very least, someone to be wildly suspicious and judgmental of...instead of another complex human being worthy of being seen and heard. I wish this world I'm speaking of was just a figment of my imagination, but we are already inside it. Our suitcases have been unpacked here for quite some time. This absolutist, authoritarian world is being fiercely crafted under the guise of 'social justice', and I want no parts in this. I AM OUT. As someone that, politically speaking, leans left on most things (although I'm neither left or right) - the current state of affairs and this push for obedience at all costs is NOT what I signed up for. I never signed up to be hit over the head with disempowering narratives that tell me that I need to refer to myself as a 'person of colour' (how is this different being called a 'coloured' person?), a minority, a marginalised person, and BAME (UK version of BIPOC). I cannot stand any of these terms. Please, if we ever need to address my racial identity, which we really don't need to do as often as you might think...BLACK works just fine, it's not a dirty word. And remember; it's okay if the language I mentioned before is affirming for you, we are allowed to disagree - but for ME, it does nothing but give me false reminders of my supposed oppression...which rubs me the wrong way entirely because I AM NOT OPPRESSED. I think it's key that we begin to accept that black people don't all share a singular experience, nor do we share the same brain. Shocking, I know. 'We are not a monolith' has become a common statement within communities that identify as marginalised, and while I wholeheartedly agree, we're definitely not a monolith... I've noticed that despite this being a popular mantra - when someone 'steps out of line' or dares to think differently...it's a different story. You will often have the pleasure of being told that you are in denial and have some kind of internalised disorder; 'internalised racism', 'internalised anti-blackness', 'internalised misogyny', 'internalised sexism', 'internalised homophobia', 'internalised transphobia', 'internalised white supremacy'... Meaning NOTHING can be questioned. Fun. Culty. Vibes. Honestly, I want better for us because it's all getting a bit much in these social justice/woke spaces, and it scares me to know that it's become controversial to address any concerns or express a differing viewpoint. It's becoming dangerous to address reality. You either agree and comply, or you shut up. I'm so happy that these are conversations that are now happening with many black people in my life, including my family who spend very little time online, are willing to have healthy debates, and couldn't give a crap about identity politics. These are the people who have really helped me free myself from the dogmatic thinking. It's necessary for me to mention that I'm having these conversations with black people because some individuals think that it's only white people who are pushing back against wokeism, and it's far from the truth. What is worrying though is how many more of us feel afraid to talk to our own friends, our partners, our spouses, our colleagues, our family - of fear of being branded as 'wrong-thinkers'. How are we supposed to understand each other if we're living in constant fear of saying the 'wrong' thing? It's even harder if you're white because there's usually someone just waiting to call you racist. And according to the woke manual, if you're white you're supposed to just accept that label. If you do question it or defend yourself, it's taken as confirmation that you ARE in fact a white supremacist. If you DARE express any fears or signs of being rightfully upset, you'll be accused of 'centering your white feelings', and of exuding 'white guilt' or 'white fragility'. With all disrespect, I don't understand the purpose of these cultish, degrading, racist terms. How are they helping us move forward? Is this true social justice? How is this helping the black community? How is this shaping a world where you and I aren't judged by the colour of our skin? Are we really trying to eradicate racism with racism? The LITERAL definition of racism is "prejudiced against or antagonistic towards a person or people on the basis of their membership of a particular racial or ethnic group". And yet some people have suddenly decided that white people cannot experience racism, nor are they permitted to dispute this insane claim. This then leads to most white people choosing to not say anything at all (which creates resentment because that's the nature of suppression & self-censorship), and some choose to comply and pretend they are on board with anything and everything (whilst also secretly resenting that they can't truly express their thoughts, ideas, feelings, etc). To me all of this confirms that when it comes to 'wokeness', critical social justice, and the beast that is cancel culture, you will never win. You will NEVER get it right. If you choose to stand back, 'educate yourself' privately and quietly; you'll be accused of being violent via your silence... And if you speak out, ask questions, or express valid confusion from the dehumanising generalisations and character assassinations; you'll be denounced for centering your 'white feelings'. This sounds like psychological warfare to me. I can't be the only one that also finds this language eerie. This is cult behaviour! And for saying the above I'm sure someone out there will lovingly label me a 'white apologist'... This is where we're at people. And like I said at the beginning, when it comes to this - I am unafraid. This is my open letter detailing some of the things that have led me to this point, because if there's anything that this past year has taught me; it's that my wellbeing and that of those around me (including the collective), is infinitely more important than any temporary discomfort that might come from me doing what I know to be right. I also want to let you know that I'm not writing this to convince you of anything, your agreement is welcome but it's not a requirement. I'm not writing this from a place of animosity or anger. I'm not writing this on behalf of any individual, group, movement, organisation, or community. I am not an activist, a social commentator, a feminist, an academic, or any other label apart from the ones I claim publicly. I am writing this to free myself. I am writing this for myself. And for you if you need it. Just like you; I am entitled to my own opinions, I have every right to question things that don't feel aligned with my values, morals, ethics, and beliefs. I have every right to push back if I recognise that I'm being forced to comply with ideologies and practices that don't make sense to me (which is how I've felt this past year). I don't want to live my life in a fearful and paranoid state. I don't want to spend my life thinking that everything that doesn't go my way is because of my skin colour, I don't want to spend the rest of my life unable to have insightful conversations with those that think differently to me...I really don't. I'm tired of hearing that because I'm black I should feel victimised. That because I'm black I should agree with everything that black people do and say (surely NO ONE should have this expected of them). None of these narrow definitions of human existence or blackness help me. None of it helps my community. It's keeping us small. It's keeping us stuck, afraid, and defensive. I reject the idea that I am a victim. I reject the idea that I am oppressed. I reject the idea that white people only exist to oppress and should be reminding me of their privilege every 2 seconds, while simultaneously telling me that they are above me. How is this helpful!? If anything, it's deeply offensive and condescending. There's no question about it; being black is a beautiful part of who I am, but it's not all I am - not even close. My identity (race, gender, sexuality, body parts) will never be more important than my humanity, my spirit, and my wholeness. EVER. Because of this, I fervently reject the idea that all white people are racist and must be shamed into confessing their sins and admitting complicity in all of their ancestors indiscretions...simply because of the colour of their skin. I reject this bullshit idea that every white person walking this planet is 'inherently racist'. Do we even know what we're saying? or are we just regurgitating/parroting things, and now it's gotten out of control. I honestly struggle to see how shaming others (or shaming yourself) for having white skin is an essential part of fuelling true social change. Surely this is regressive? It also sounds a little like the very thing we've spent years moving away from... The truth of the matter is that my own ancestors have participated in some FUCKERY and I would not want to live the rest of my life being punished for their actions. A lot of what I'm seeing in the woke/critical social justice spaces is not about creating a better world, it seems to be about punishment and revenge. And it's doing nothing but trampling on the work true Activists are doing and have been doing for centuries! I do have to take a moment to acknowledge those who are doing fantastic work and making a long-lasting impact in their communities, instead of perpetuating fear and manipulating people's emotions by convincing them they will always be victims. I'm done with the insidious brainwashing of wokeness. I'm committed to understanding human behaviour (this is also at the core of what I do professionally), I'm committed to compassion and kindness without excusing that which must be acknowledged. I'm well aware of the systems we live under. I know what's happening in the world. I've lived it. I acknowledge reality, but I refuse to be a slave to a disempowering narrative that rarely focuses on actual solutions. I never want to forget that you can still be compassionate with those you don't agree with. And this way of thinking is what I CHOOSE because it makes my time on planet earth better, you don't have to take it on if it doesn't work for you. I want to live a life that isn't centred around identity politics and all that comes with it, so much more in my life takes priority. I want to remain open to new ideas, perspectives, and thoughts - so that I can grow, course correct where necessary, and make a genuine impact on a local and global level. I want to give people the benefit of the doubt and continue using discernment instead of making sweeping harmful (often lazy) assumptions based on the colour of people's skin or their gender. I refuse to take on the black or white thinking because I've seen and experienced the grave harm that does. As I move into this next season of my life, I'm more interested in the grey area - where we all exist. The nail in the coffin for me was all the events that took place last Summer. Last Summer in the height of the Black Lives Matter movement, I noticed a shadowy part of me emerging and although I didn't judge it, I wasn't comfortable with what was coming up. All the critical social justice dogma I'd been consciously and unconsciously imbibing over the past 2 years began taking a HUGE toll on my mental health, and I hadn't even realised that I wasn't functioning as a full human being - until it reached it's peak. The unpleasant internal experience I had is what led me where I am now, which is why I'm a firm believer that welcoming discomfort in is one of the most loving things you can do for yourself. On social media at that time I was DEEP is various social justice echo chambers that shared more than enough infographics, stories, feed posts, IG LIVES, to make my fight or flight response go nuts. I was in constant fight mode, and wasn't aware. I was being indoctrinated; this means "to teach a person or a group to accept a set of beliefs uncritically". I found myself subconsciously looking for things that would piss me off, which is a symptom of wokeness that seems to show up in many people - hundreds of you have shared your own experiences with me in the past month alone and the similarities in our stories are alarming. Before reacting to things, I did ZERO in-depth research of my own. It's almost as if facts were an unwelcome guest. Anything that didn't align with the beliefs I held about race, sex, gender, politics, etc - I rejected (this was all unconscious). I didn't question the sources I was getting information from, it was all taken as objective truth. It was ALL reactionary, I was on autopilot. I didn't realise I had many people on pedestals that they shouldn't have been on in the first place (no fault of their own, I put them there), I was operating purely based on emotions and feelings that gave my nervous system the signal that I was under threat. And that's the energy I acted and spoke from. I rashly unfollowed some people on my social media who I'd decided should have 'spoken up' in support of Black Lives Matter (an organisationI have now done my own extensive research on, but that's a whole other story) - simply because (based on my egos time frame) they weren't responding as and when they 'should' have. I'm sure I re-shared something about 'white silence' being 'violence' (an oversimplified and unfair statement I no longer agree with, and you can watch the lengthy live I did with Rukiat where I go into some of this). I also publicly shamed an unsuspecting man who had messaged me to question me about my conduct (I immediately assumed he was white...he was mixed race). And even though his approach was not a welcome one, he wasn't unkind to me - which is why I'm not proud of the unkind way in which I reacted...not responded, reacted. What frightened me was the applause I got from over 4,000 people when I called out this man in an Instagram post - I didn't say anything wild, but I did deconstruct his direct message publicly with the intention to embarrass him, not to resolve anything - to embarrass. I was honestly shocked by how many people used the environment I had created to exercise pack mentality, and to casually shame and scold a stranger - of which I take responsibility for as the person that created that environment. I now know that publicly shaming someone is a common tactic used in most woke spaces and echo chambers on social media, and it's so normalised. This is the kind of thing that quickly leads to bullying, doxing, stalking, and harassment...and sometimes ends in suicide. After seeing the responses applauding me, I removed the post and started asking myself some questions; who am I doing this for? why did my interaction with this man need to be publicised? what is really the root of the anger I feel? is this a performance on my behalf? what research have I done to support the ideology I'm leading with? are there any alternative sources that can give me more information or provide clarity on the situation I'm reacting to? do I really believe this or am I regurgitating something I read/heard/saw somewhere? I'm of the thinking that there is such a thing as justified anger, and I believe that all emotions and modes of expressions have their place - but I know myself well enough to know that the way I handled that particular situation was not necessary. This incident led me start evaluating my own behaviour and doing more research around the cancel culture phenomenon. And it's just one recent example of how some of this stuff has showed up in my life over the past 2 years. SO, why am I calling 'WOKENESS' a cult? Well, first lets start by defining what the term woke even means. It's a term that been around for a very long time but has (in my eyes) lost all of it's credibility and meaning in recent years. Woke: a term embedded in US Black History and social justice which originally meant being aware, well-informed, and up to date with what was happening within the community. "Stay woke became a watch word in parts of the black community for those who considered themselves self-aware, questioning the dominant paradigm, and striving for something better" - and these are the sentiments I will always stand for, however... This is NOT how it's playing out these days, and you can read this interesting article to get a timeline of how it's evolved over the years, and I'll continue sharing with you the specific pockets of 'wokeness' and social justice that I have divorced myself from. I can no longer be an active participant in any culture or movement that encourages groupthink, outrage on demand, fear and violence, revamped segregation, fabricating history, cancellations masked as accountability, self-centredness... normalisation of racism towards white people, the disempowerment of black people masked as social justice, the constant redefining of existing language, ignoring self-responsibility, constant pathologizing, oppressed vs oppressor mentality, and the pressure to conform and comply... It's exhausting. And honestly, I have better things to do with my time. Not to mention, it's killing us. I also find it very telling that people who are married to these woke spaces will immediately assume that those that are requesting for more compassion, understanding, room for discussion, removal of censorship - only want these things so they can have free reign to be bigots, sexist, 'fascists', racists, homophobes, etc. As a free-thinking black woman who most definitely wants more compassion, understanding, healthy discussion, empathy, removal of censorship, more tolerance and acceptance when it matters most...I can guarantee you that my final goal isn't so I can be a racist sexist fascist alt-righter extremist. LOL. And if you can understand this, what makes someone who happens to be white any less sincere if they want the exact same thing as me? Which many people do! I hope you can sort of see just how oversimplified and flawed this madness is. I often laugh about the ridiculous nature of it all, but what's concerning is that it's spreading like wildfire, it's causing lasting harm, and it's distracting us from the very real work that needs to be done to tackle injustice and unite us as human beings. I will stick to my guns by saying that the turn we're taking because of critical social justice and this current strain of branded monetised wokeness - is not going to take us to the promised land (SPOILER: there is no utopia, I'm sorry to break it to you). As someone who will never stop advocating for human rights (fairness, equality, access to resources, respect, independence - for ALL, not just for people who share my skin tone and gender), I have come to realise that I do not need to be part of any groups or wear any labels to make a positive contribution to this planet of ours. This is also why I do not identify as a feminist. Just like everything else I've spoken about so far; the current wave of commodified feminism is so far removed from my core values; honesty, respect, interconnection, equality, individuality etc. There's a lot of self-righteousness, virtue signalling, self-centeredness, and a lack of empathy in most of what I see being presented today as feminism - and again; it seems to be about revenge, superiority, and personal branding. It's also not uncommon to be made to feel unintelligent, wrong, and inferior in a lot of these supposedly 'safe spaces' - simply because you don't identify with the label or agree with all the view points of the group. IT'S TIRING, and I wish more people knew that you can still believe in and advocate for equality and fairness without wearing a label like a badge of honour. My mission isn't to be superior to anyone, nor do I want to see the demise of any gender. I believe that we should all have equal rights and opportunities, and I'm also realistic about the differences we have as human beings - I celebrate those differences. In a world obsessed with labels and titles, I would rather let my values and actions speak for themselves. These are the times when I am incredibly grateful for the upbringing I've had, both in Zimbabwe and here in the UK. I'm grateful that I was raised to think for myself, and that's what I'll continue to do. I was raised to not judge people based on the colour of their skin, gender, class etc - no matter what. And that's what I'll continue to do. YES, I could choose to carry animosity in my heart based on the pain my ancestors experienced and the injustice still taking place in many different parts of the world - but what does that do for me, my mental state, my community, and those I interact with in the present day? I'd rather acknowledge reality, and focus on solutions. I wasn't really raised to ask many questions, but in adulthood asking powerful questions (even when they are simple) is something that has become a non-negotiable - and that's what I will continue to do. I will continue to trust myself and question things. I will do my own research before responding purely based on emotion. I will keep myself open to having challenging conversations if I have the capacity to do so, and if I don't have the capacity to engage, I will still not shut anyone down - unless absolutely necessary. My biggest realisation has been that most of these people that pose as Social Justice Warriors, Activists, Agents of Change etc - don't actually want to improve and repair society. They don't want a better world. For some the goal is to make things worse. A lot of the people I know in these spaces have brands, careers, and management teams from this. Their livelihood depends on them playing this role, which often means that they will continue to find everything wrong with society instead of making consistent efforts to unite and truly empower. There's a sinister side many people aren't comfortable speaking about because of the potential backlash, and it's unfair to those of us who end up being sucked into these echo chambers and movements through the promise of community and betterment. Most of us just want to help. We want to see change! In our personal lives, and in the world we exist in. This leaves us vulnerable to questionable 'leaders', influencers, and organisations who set themselves up so that you cannot question their practices or agenda. The similarities of wokeness/critical social justice to fundamentalist religion (something I'm VERY familiar with) is why I choose to call it a cult, the framework and tactics are eerily similar... It usually goes a little like this; find/attract a vulnerable person, make them feel like they belong so they can trust you, tell them exactly what they want to hear, and once they become loyal - it is easier to sell them outlandish concepts and to make them 'repent' for 'sins' they have supposedly committed... the person then regresses and begins to rely on their 'leader' or the ideology to shape their thoughts and their world view. They are introduced to an enemy and are encouraged to cut themselves off from the outside world and anyone else who doesn't agree with or follow the ideology (us vs them mentality). Once cut off from everyone, the individual is more dependent on the leader or the group, and then it becomes increasingly difficult to leave. Just like an abusive relationship! This is exactly what I'm seeing in the woke/feminist/critical social justice spaces. Despite it all, the individual is often unaware of what's really happening and will continue to believe that they are acting on their own accord. The prison walls remain invisible. But it's possible to break out! It's why I've decided to speak out. And if you don't agree with what I'm sharing, and this has not been your experience - that's okay. I will always respect your right to own your experiences and perspectives. I ask that you do the same for me. We live different lives, we have different views. It's normal. What ISN'T normal, is forcing people to comply and bow down to an ideology, simply because YOU think it's the right one. If you resonate with what I've shared in this letter, please know that you are not alone. You are allowed to change your mind. You are allowed to grow. You are allowed to walk away. You are allowed to put your foot down. There is no one way to 'do the work'. You don't have to pray to a single political idea, movement, or group - nor do you have to agree with EVERYTHING presented to you as the absolute truth. You are not morally inferior or superior to anyone else. And remember that we still have to co-exist on this planet, so expecting everyone you encounter to agree with every belief or view that you hold - is fucking wild, LOL. If you have read this far, I appreciate your time and your attention. Any typos you see, represent the sheer passion flowing through me. I'll stop here because I could go on, there is always more to say. I feel like this letter is just the foundation of the conversations I REALLY want to have so I will likely explore some of the specificities in podcast form and through my newsletter. I'm considering producing and hosting a limited podcast series that specifically talks about these themes. Don't worry, my existing podcastBeyond the Self won't be going anywhere! In the meantime; you can find me on Instagram if we're not already connected. Although my work as a Mindset Coach, Speaker, and Consultant has nothing to do with social justice, cancel culture, wokeness etc - this is something I'll continue to speak about because it directly speaks to 2 of my biggest areas of focus, which in this case are collective self-sabotage and psychological manipulation. I encourage you to break out of any echo chambers (especially on social media) and explore yourself BEYOND your race, your pronouns, your genitals, your sexuality, your physical capabilities, your politics - those things have their place but there is so much more to you. And in fact, when you do go beyond those neatly prescribed boxes, you become more secure within your identity. I urge you to unsubscribe to anyone and anything that is stripping you of your humanity, your agency, and is proving to be detrimental to your mental wellbeing. You deserve better, let's never stop speaking up! Love always, Africa   (NEXT) Lawsuit accuses COVID-19 testing company of faking results   Washington state Attorney General Bob Ferguson has filed a lawsuit against an Illinois-based COVID-19 testing company, accusing it of improperly handling tests and providing fake negative results.   The Associated Press, January 31, 2022   Washington state Attorney General Bob Ferguson has filed a lawsuit against an Illinois-based COVID-19 testing company, accusing it of improperly handling tests and providing fake results. It describes how the company expanded to about 300 locations throughout the United States and collected tens of thousands of tests a day. “Center for COVID Control contributed to the spread of COVID-19 when it provided false negative results,” Ferguson said in a statement. “These sham testing centers threatened the health and safety of our communities. They must be held accountable.” The lawsuit also said the Center for COVID Control stored tests in garbage bags — rather than properly refrigerating them — backdated sample-collection dates so stale samples would still be processed and instructed its employees to lie when Washington residents asked about delayed results. The lawsuit asks the court to order the Center for COVID Control to pay civil penalties of up to $12,500 per violation of the Consumer Protection Act and relinquish any profits the company made from its “unlawful conduct,” in addition to permanently closing all locations, the statement said.

Od nauczania do uczenia się
ONDU#127: Jak środowisko wpływa na mózg dziecka?- prof. Krystyna Rymarczyk.

Od nauczania do uczenia się

Play Episode Listen Later Feb 2, 2022 79:07


Obserwujemy coraz większy wpływ pandemii na odpornośc psychiczną dorosłych jak i na dzieci. Dzieci, niestety mają przez pandemię zakłócony proces rozwoju i będziemy musieli być jeszcze bardziej wyczuleni na ich potrzeby emocjonalne. Jak rozpoznać sytuację, w której dziecko oczekuje już pomocy z zewnątrz? Czy jesteśmy w stanie zaobserwować symptomy nieuzbrojonym okiem? Zapraszamy na bardzo ciekawa rozmowę z naszym gościem Krystyna Rymarczyk, profesor Uniwersytetu Społeczno-Humanistycznego SWPS, w Katedrze Psychologii Poznawczej i Behawioralnej Wydziału Psychologii SWPS w Warszawie. Przez latapracowała także w Pracowni Psychofizjologii w Instytucie Biologii Doświadczalnej PAN w Warszawie. Obecnie prowadzi zajęcia na studiach magisterskich i podyplomowych z zakresu neuropsychologii klinicznej, neuronauki oraz neurologopedii. Jej zainteresowania naukowekoncentrują się wokół zagadnienia powstawania reakcji mimicznych, mózgowej organizacji procesów emocjonalnych. W tym obszarze prowadzi badania z wykorzystaniem funkcjonalnego rezonansu magnetycznego (fMRI) jak i elektromiografii powierzchniowej mięśni twarzy (EMG). Jestautorką kilkudziesięciu artykułów zarówno z zakresu neuronauki społecznej, jak i psychologii m.in. Scientific Reports, PLOS One, Frontiers in Psychology, Frontiers in Behavioral Neuroscience i inne.Interesuje się także neurobiologicznym podłożem rozwoju człowieka, mechanizmami plastyczności mózgowej, wpływem aktywności fizycznej na rozwój mózgu dziecka i tej tematyce także poświęca swoje publikacje.