Podcasts about PLOS One

https://www.youtube.com/watch?v=XIwEc64h-BE 0:00 เริ่ม ทักทาย พูดถึงความประทับใจงาน WiT meet ที่จบไป 15:10 เล่าเรื่องเคยเจอคุณ Jane Goodall 20:47 กลับมาเล่าเรื่องแฟนมีตต่อ รีแคปเรื่องตราปั๊มพ์ เพลง และพิธีกรรมเปิดงาน 33:03 เพลงบูชาเทพ เอนุสซู 44:05 ลิสต์รางวัล Ig Nobel 2025 สาขาต่างๆ 1:09:01 เล่ารายละเอียด กิ้งก่ากินพิซซ่า 1:19:17 คุยยาวเรื่อง narcissist 1:59:39 ชั้นรองเท้าดับกลิ่น 2:05:19 อาบันเสริมเรื่อง narcissist ต่ออีกหน่อย 2:17:08 unbox อวดผลงานชาวเบร้อ art toy ธีมแมลงโดนเชื้อราซอมบี้จากอวกาศ ซีรีส์ Bug Light Year โดย @vectorfigure 2:25:51 ค้างคาวเมา 2:41:49 วัวลาย เหลือบไม่ชอบตอม 2:51:49 แม่นมกระเทียม 3:12:35 ประชาสัมพันธ์ และบอกลาผู้ฟัง https://www.youtube.com/watch?v=UiGLm7_-la4 รางวัลสาขา โภชนาการ มอบให้ Daniele Dendi และคณะ กับผลงานศึกษาว่า กิ้งก่าชนิดเจาะจงชนิดหนึ่ง มีความชอบกินพิซซ่าแต่ละหน้าแตกต่างกันมากน้อยแค่ไหน REFERENCE: “Opportunistic Foraging Strategy of Rainbow Lizards at a Seaside Resort in Togo,” Daniele Dendi, Gabriel H. Segniagbeto, Roger Meek, and Luca Luiselli, African Journal of Ecology, vol. 61, no. 1, 2023, pp. 226-227. เกร็ดเสริมเรื่องกิ้งก่าขี้ไม่ออก https://www.livescience.com/constipated-lizard-record-breaking-poo.html รางวัลสาขา จิตวิทยา มอบให้ Marcin Zajenkowski และ Gilles Gignac กับผลงานศึกษาว่าเกิดอะไรขึ้น เมื่อคุณบอกคนที่เป็นนาร์ซิซิสต์ หรือใครก็ตาม ว่าเขานั้นฉลาดกว่าคนอื่น REFERENCE: “Telling People They Are Intelligent Correlates with the Feeling of Narcissistic Uniqueness: The Influence of IQ Feedback on Temporary State Narcissism,” Marcin Zajenkowski and Gilles E. Gignac, Intelligence, vol. 89, November–December 2021, 101595. รางวัลสาขา การออกแบบทางวิศวกรรม มอบให้ Vikash Kumar และ Sarthak Mittal ผู้ทำการวิเคราะห์จากมุมมองของการออกแบบเชิงวิศวกรรมว่า รองเท้าที่เหม็นโฉ่วนั้นส่งผลลบต่อประสบการณ์ที่ดีในการใช้ชั้นรองเท้า REFERENCE: “Smelly Shoes — An Opportunity for Shoe Rack Re-Design,” Vikash Kumar and Sarthak Mittal, Ergonomics for Improved Productivity: Proceedings of HWWE 2017, vol. 2, pp. 287-293. Springer Singapore, 2022. ผลงานชาวเบร้อ Art toy ธีมแมลงกับเชื้อราซอมบี้ต่างดาว โดย https://www.instagram.com/vectorfigure รางวัลสาขา การบิน มอบให้ Francisco Sánchez และคณะ สำหรับการศึกษาที่ค้นพบว่า การบริโภคแอลกอฮอลสามารถลดสมรรถนะการบินของค้างคาว ตลอดจนขัดขวางทักษะการใช้เสียงสะท้อนนำร่อง REFERENCE: “Ethanol Ingestion Affects Flight Performance and Echolocation in Egyptian Fruit Bats,” Francisco Sánchez, Mariana Melcón, Carmi Korine, and Berry Pinshow, Behavioural Processes, vol. 84, no. 2, 2010, pp. 555-558. แถมเรื่องค้าวคาวลึงค์ใหญ่ รางวัลสาขา ชีววิทยา มอบให้กับ Tomoki Kojima และคณะ กับผลงานวิจัยที่ทดสอบว่า วัวซึ่งถูกทาสีเป็นลายม้าลาย จะโดนเหลือบกัดน้อยลงหรือไม่ REFERENCE: “Cows Painted with Zebra-Like Striping Can Avoid Biting Fly Attack,” Tomoki Kojima, Kazato Oishi, Yasushi Matsubara, Yuki Uchiyama, Yoshihiko Fukushima, Naoto Aoki, Say Sato, Tatsuaki Masuda, Junichi Ueda, Hiroyuki Hirooka, and Katsutoshi Kino, PLoS ONE, vol. 14, no. 10, 2019, e0223447. รางวัลสาขา กุมารเวช มอบให้ Julie Mennella และ Gary Beauchamp สำหรับงานวิจัยประสบการณ์ของเด็กทารกเมื่อแม่กินกระเทียมแล้วมาให้นม REFERENCE: “Maternal Diet Alters the Sensory Qualities of Human Milk and the Nursling's Behavior,” Julie A. Mennella and Gary K. Beauchamp, Pediatrics, vol. 88, no. 4, 1991, pp. 737-744. รวม podcast ที่เล่า Ig Nobel ปีนี้ หรือสัมภาษณ์นักวิจัยที่ได้รางวัล Stuff to Blow Your Mind 632 nm podcast

In this episode of The Lebanese Physicians Podcast, I speak with Dr. Michelle Cherro, Child and Adolescent Psychiatry Fellow at Mass General in Boston and lead author of the 2025 PLOS One study, “Predictors of suicide attempts among adolescents with suicidal ideations and a plan.” Dr. Cherro discusses the motivations behind her team's work with co-authors Dr. Hala Itani, Dr. Elie Ghossoub, and Dr. Fadi Maalouf at the American University of Beirut, exploring what drives some adolescents from suicidal thoughts and planning to an actual suicide attempt.   We unpack the study's key findings, that female adolescents, antisocial behaviors, and substance use strongly predict attempts, and discuss how these insights can inform prevention efforts in Lebanon where the rates are not higher than elsewhere despite the unstable economic and political situation.   Tune in for a compelling conversation bridging U.S.-based data with Lebanese mental-health realities, and for practical reflections on what clinicians, schools, and families can do to protect at-risk youth.  

Suite à une conférence débat menée en janvier 2018 sur l'initiation de la dialyse, le choix de la modalité et la prescription, il a été recommandé le recours à la prise de décision partagée entre le patient et l'équipe de soins pour établir des objectifs de traitement permettant au patient d'atteindre ses propres objectifs de vie et au clinicien de prescrire une dialyse personnalisée de haute qualité1. Mais concrètement, qu'est-ce que la décision médicale partagée (DMP) ? Quels sont les avantages de la DMP et quels sont les moyens possibles pour la développer ?  Le Dr Pierre Housset, néphrologue au Centre Hospitalier Sud Francilien, répond à vos questions.   Invité : Dr Pierre Housset, néphrologue au Centre Hospitalier Sud Francilien Le Dr Housset déclare ne pas avoir de lien d'intérêt en rapport avec le sujet traité.   L'équipe :
 Animation :  Pyramidale Communication Production : Pyramidale Communication   Crédits : Pyramidale Communication, Sonacom   Ce podcast est uniquement destiné à des fins d'information. Si vous souhaitez contacter Baxter pour de plus amples informations ou pour signaler un événement indésirable, veuillez consulter notre site web à l'adresse suivante : https://www.baxter.fr/fr/contact-us   Références : 1. Chan CT et al. Dialysis initiation modality choice, access, and prescription: conclusions from Kidney Disease: Improving Goal Outcomes (KDIGO) Controversies Conference. Kidney International 2019 2. HAS, Patient et professionnels de santé : décider ensemble. 2013 3. Prieto-Velasco M, Quiros P, Remon C, Spanish Group for the Implementation of a Shared Decision Making Process for RRT Choice with Patient Decision Aid Tools (2015) The Concordance between Patients' Renal Replacement Therapy Choice and Definitive Modality: Is It a Utopia?. PLOS ONE 10(10): e0138811. 4. Ramer SJ, McCall NN, Robinson-Cohen C, Siew ED, Salat H, Bian A, Stewart TG, El-Sourady MH, Karlekar M, Lipworth L, Ikizler TA, Abdel-Kader K. Health Outcome Priorities of Older Adults with Advanced CKD and Concordance with Their Nephrology Providers' Perceptions. J Am Soc Nephrol. 2018 Dec;29(12):2870-2878. doi: 10.1681/ASN.2018060657. Epub 2018 Nov 1. PMID: 30385652; PMCID: PMC6287864. 5. Mendelssohn DC, et al. A prospective evaluation of renal replacement therapy modality eligibility. Nephrol Dial Transplant. 2009;24(2):555-561. 6. Oliver MJ, et al. Impact of contraindications, barriers to self-care and support on incident peritoneal dialysis utilization. Nephrol Dial Transplant. 2010; 25(8): 2737-2744. 7. de Jong RW, Stel VS, Rahmel A, Murphy M, Vanholder RC, Massy ZA, Jager KJ. Patient-reported factors influencing the choice of their kidney replacement treatment modality. Nephrol Dial Transplant. 2022 Feb 25;37(3):477-488. doi: 10.1093/ndt/gfab059. PMID: 33677544; PMCID: PMC8875472.

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers goals of care conversations.Our guest for this episode is Dr. Tavis Apramian, a clinician-investigator in the Department of Family & Community Medicine (DFCM) at the University of Toronto and scientist in the Office of Education Scholarship. He works as a palliative care physician at St. Michael's Hospital and at Kensington Hospice. His largely qualitative program of research is focused on advance care planning; workplace-based learning and assessment; palliative care in family medicine; medical assistance in dying; and inequity in end-of-life care. His primary focus is on telling rich stories of learner and patient experiences to spark conversation about socioculturally complex educational and clinical problems in serious illness.The learning objectives for this episode are as follows:Describe a palliative approach to care and its relevance across different contextsDemonstrate a structured and compassionate approach to goals of care conversationsApply effective communication strategies to build therapeutic alliance, navigate difficult conversations, and involve multiple actors in the palliative contextRecognize and manage challenges in goals of care conversationsGuest: Dr. Tavis ApramianHosts: Dr. Daamoon Ghahari (PGY2) and Dr. Angad Singh (PGY2)Audio editing: Dr. Angad Singh (PGY2)Timestamps:(1:07) - Journey to palliative care(5:07) - What is palliative care(14:47) - Understanding patient values(33:47) - Structuring goals of care conversations(44:16) - Communication strategies(57:05) - Navigating family meetings(77:25) - Reflections on MAiD for sole mental illnessResources:Roth, H. (2024). Hearing the unspoken. Canadian Family Physician, 70(10), 642-642. https://pmc.ncbi.nlm.nih.gov/articles/PMC11477260/pdf/0700642.pdfReferences:Bernacki, R. E., & Block, S. D. (2014). Communication about serious illness care goals: a review and synthesis of best practices. JAMA internal medicine, 174(12), 1994-2003.Gross, J., & Koffman, J. (2024). Examining how goals of care communication are conducted between doctors and patients with severe acute illness in hospital settings: A realist systematic review. PLoS One, 19(3), e0299933.Scheunemann, L. P., Ernecoff, N. C., Buddadhumaruk, P., Carson, S. S., Hough, C. L., Curtis, J. R., ... & White, D. B. (2019). Clinician-family communication about patients' values and preferences in intensive care units. JAMA internal medicine, 179(5), 676-684.You, J. J., Downar, J., Fowler, R. A., Lamontagne, F., Ma, I. W., Jayaraman, D., ... & Canadian Researchers at the End of Life Network (CARENET). (2015). Barriers to goals of care discussions with seriously ill hospitalized patients and their families: a multicenter survey of clinicians. JAMA Internal Medicine, 175(4), 549-556.For more PsychEd, follow us on Instagram (⁠@psyched.podcast⁠),  Facebook (⁠PsychEd Podcast⁠), X (⁠@psychedpodcast⁠), and Bluesky (⁠@psychedpodcast.bsky.social‬⁠). You can email us at ⁠psychedpodcast@gmail.com⁠ and visit our website at⁠ ⁠⁠psychedpodcast.org⁠.

Mit den kürzeren Tagen sinkt bei vielen Menschen nicht nur die Energie, sondern auch ihr Vitamin-D-Spiegel. Rutscht er zu sehr ab, hat das Folgen für Leistungsfähigkeit, Immunsystem und Stimmung.Eine neue Studie deutet darauf hin, dass Indoor-Training den im Winter üblichen Vitamin-D-Abfall messbar ausbremst. Kann Deine Fitness-Routine also das Vitamin-D-Supplement ersetzen? Am Ende der Folge bist Du auf Stand und weißt, was das für Dich und Deinen Vitamin-D-Haushalt bedeutet.Außerdem bekommst Du eine klare Strategie an die Hand, um die dunklen Monate von Oktober bis März energiegeladen (und mit vollen Vitamin-D-Speichern) zu überbrücken – statt im Wintermodus auf Reserve zu laufen.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________Tools (Marks Empfehlungen):Vitamin-D-Selbsttest von Medivere.Vitamin-D-Präparat mit 2.000 IE von FormMed (vegane Variante).Weiterführende Inhalte:Download: Ratgeber NahrungsergänzungFolge 502: "Brauchen Sportler Nahrungsergänzung, Herr Ernährungsmediziner?" Mit Niels Schulz-RuhtenbergWissenschaftliche Literatur:Perkin OJ, Davies SE, Hewison M, et al. Exercise without weight loss prevents seasonal decline in vitamin D metabolites: The VitaDEx randomized controlled trial. Advanced Science. 2025;12(22):e2416312.Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications. Chemistry & Biology. 2014;21(3):319-329.Webb AR, Kazantzidis A, Kift RC, Farrar MD, Wilkinson J, Rhodes LE. Meeting vitamin D requirements in white Caucasians at UK latitudes: Providing a choice. Nutrients. 2018;10(4):497.Lin LY, Smeeth L, Langan S, Warren-Gash C. Distribution of vitamin D status in the UK: a cross-sectional analysis of UK Biobank. BMJ Open. 2021;11(1):e038503.de Oliveira LF, de Azevedo LG, da Mota Santana J, de Sales LPC, Pereira-Santos M. Obesity and overweight decreases the effect of vitamin D supplementation in adults: Systematic review and meta-analysis of randomized controlled trials. Reviews in Endocrine and Metabolic Disorders. 2020;21(1):67-76.Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr. 2000;72(3):690-693.Drincic AT, Armas LAG, Van Diest EE, Heaney RP. Volumetric dilution, rather than sequestration best explains the low vitamin D status of obesity. Obesity (Silver Spring). 2012;20(7):1444-1448.Ekwaru JP, Zwicker JD, Holick MF, Giovannucci E, Veugelers PJ. The importance of body weight for the dose response relationship of oral vitamin D supplementation and serum 25-hydroxyvitamin D in healthy volunteers. PLoS One. 2014;9(11):e111265.Sun X, Cao ZB, Taniguchi H, Tanisawa K, Higuchi M. Effect of an acute bout of endurance exercise on serum 25(OH)D concentrations in young adults. Journal of Clinical Endocrinology & Metabolism. 2017;102(11):3937-3944.____________Shownotes und Übersicht aller Folgen.Trag Dich in Marks Dranbleiber Newsletter ein.Entdecke Marks Bücher.Folge Mark auf Instagram, Facebook, Strava, LinkedIn. Hosted on Acast. See acast.com/privacy for more information.

In our first episode released in both English and Spanish, Drs. Laila Woc-Colburn and Nicholás Ignacio Valdebenito Farías join Dr. José Pablo Díaz Madriz to discuss the role of the pharmacist in antimicrobial stewardship in Latin America. They discuss the need for growth of antimicrobial stewardship programs across Latin America, how pharmacists can expand their roles to support multidisciplinary antimicrobial stewardship teams, and much more!   Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/. Visit our website! https://breakpoints-sidp.org/ References: Ciapponi A, Bardach A, Sandoval MM, Palermo MC, Navarro E, Espinal C, Quirós R. Systematic review and meta-analysis of deaths attributable to antimicrobial resistance, Latin America. Emerg Infect Dis. 2023 Nov;29(11):2335-44. doi:10.3201/eid2911.230753. PMID:37877573; PMCID:PMC10617342. Antimicrobial Resistance Collaborators. The burden of antimicrobial resistance in the Americas in 2019: a cross-country systematic analysis. Lancet Reg Health Am. 2023 Aug 8;25:100561. doi:10.1016/j.lana.2023.100561. Erratum in: Lancet Reg Health Am. 2023 Nov 10;28:100632. doi:10.1016/j.lana.2023.100632. PMID:37727594; PMCID:PMC10505822. Fabre V, Secaira C, Cosgrove SE, Lessa FC, Patel TS, Alvarez AA, Anchiraico LM, Del Carmen Bangher M, Barberis MF, Burokas MS, Castañeda X, Colque AM, De Ascencao G, Esquivel C, Ezcurra C, Falleroni LA, Frassone N, Garzón MI, Gomez C, Gonzalez JA, Hernandez D, Laplume D, Lemir CG, Maldonado Briones H, Melgar M, Mesplet F, Martinez G, Pertuz CM, Moreno C, Nemirovsky C, Nuccetelli Y, Palacio B, Sandoval N, Vergara H, Videla H, Villamandos S, Villareal O, Viteri A, Quiros R. Deep dive into gaps and barriers to implementation of antimicrobial stewardship programs in hospitals in Latin America. Clin Infect Dis. 2023 Jul 5;77(Suppl 1):S53-S61. doi:10.1093/cid/ciad184. PMID:37406044; PMCID:PMC10321692. Charani E, Smith I, Skodvin B, Perozziello A, Lucet JC, Lescure FX, Birgand G, Poda A, Ahmad R, Singh S, Holmes AH. Investigating the cultural and contextual determinants of antimicrobial stewardship programmes across low-, middle- and high-income countries: a qualitative study. PLoS One. 2019 Jan 16;14(1):e0209847. doi:10.1371/journal.pone.0209847. PMID:30650099; PMCID:PMC6335060. Bavestrello L, Cabello Á, Casanova D. Impact of regulatory measures on antibiotic sales in Chile. Rev Med Chil. 2002 Nov;130(11):1265-72. doi:10.4067/S0034-98872002001100009. ISSN 0034-9887. Díaz-Madriz JP, et al. Impact of a pharmacist-driven antimicrobial stewardship program in a private hospital in Costa Rica. Rev Panam Salud Publica. 2020;44:e57. doi:10.26633/RPSP.2020.57. Díaz-Madriz JP, et al. Impact of a pharmacist-driven antimicrobial stewardship program on the prescription of antibiotics by intensive care physicians in a Latin American hospital: a retrospective study. J Am Coll Clin Pharm. 2022;5(11):1148-55. doi:10.1002/jac5.1708. Domínguez I, et al. Evaluación del consumo de antimicrobianos en 15 hospitales chilenos: resultados de un trabajo colaborativo, 2013. Rev Chil Infectol. 2016 Jun;33(3):307-12. doi:10.4067/S0716-10182016000300010. ISSN 0716-1018. Ministerio de Salud de Chile. Norma general técnica N°210 para la racionalización del uso de antimicrobianos en la atención clínica. Resolución Exenta N°1146, 2020. Disponible en: https://diprece.minsal.cl/wp-content/uploads/2021/01/RES.-EXENTA-N%C2%B01146-Aprueba-Norma-Gral.-Te%CC%81cnica-N%C2%B00210-para-la-racionalizacio%CC%81n-del-uso-de-antimicrobianos-en-la-Atencio%CC%81n-Cli%CC%81nica_v2.pdf

En nuestro primer episodio publicado tanto en inglés como en español, la Dra. Laila Woc-Colburn y el QF. Nicolás Ignacio Valdebenito Farías se unen al Dr. José Pablo Díaz Madriz para hablar sobre el papel del farmacéutico en los PROA en América Latina. Ellos discuten la necesidad de expandir los PROA en toda la región, cómo los farmacéuticos pueden ampliar sus funciones para apoyar equipos multidisciplinarios dedicados a esta labor, ¡y mucho más! Ciapponi A, Bardach A, Sandoval MM, Palermo MC, Navarro E, Espinal C, Quirós R. Systematic review and meta-analysis of deaths attributable to antimicrobial resistance, Latin America. Emerg Infect Dis. 2023 Nov;29(11):2335-44. doi:10.3201/eid2911.230753. PMID:37877573; PMCID:PMC10617342. Antimicrobial Resistance Collaborators. The burden of antimicrobial resistance in the Americas in 2019: a cross-country systematic analysis. Lancet Reg Health Am. 2023 Aug 8;25:100561. doi:10.1016/j.lana.2023.100561. Erratum in: Lancet Reg Health Am. 2023 Nov 10;28:100632. doi:10.1016/j.lana.2023.100632. PMID:37727594; PMCID:PMC10505822. Fabre V, Secaira C, Cosgrove SE, Lessa FC, Patel TS, Alvarez AA, Anchiraico LM, Del Carmen Bangher M, Barberis MF, Burokas MS, Castañeda X, Colque AM, De Ascencao G, Esquivel C, Ezcurra C, Falleroni LA, Frassone N, Garzón MI, Gomez C, Gonzalez JA, Hernandez D, Laplume D, Lemir CG, Maldonado Briones H, Melgar M, Mesplet F, Martinez G, Pertuz CM, Moreno C, Nemirovsky C, Nuccetelli Y, Palacio B, Sandoval N, Vergara H, Videla H, Villamandos S, Villareal O, Viteri A, Quiros R. Deep dive into gaps and barriers to implementation of antimicrobial stewardship programs in hospitals in Latin America. Clin Infect Dis. 2023 Jul 5;77(Suppl 1):S53-S61. doi:10.1093/cid/ciad184. PMID:37406044; PMCID:PMC10321692. Charani E, Smith I, Skodvin B, Perozziello A, Lucet JC, Lescure FX, Birgand G, Poda A, Ahmad R, Singh S, Holmes AH. Investigating the cultural and contextual determinants of antimicrobial stewardship programmes across low-, middle- and high-income countries: a qualitative study. PLoS One. 2019 Jan 16;14(1):e0209847. doi:10.1371/journal.pone.0209847. PMID:30650099; PMCID:PMC6335060. Bavestrello L, Cabello Á, Casanova D. Impact of regulatory measures on antibiotic sales in Chile. Rev Med Chil. 2002 Nov;130(11):1265-72. doi:10.4067/S0034-98872002001100009. ISSN 0034-9887. Díaz-Madriz JP, et al. Impact of a pharmacist-driven antimicrobial stewardship program in a private hospital in Costa Rica. Rev Panam Salud Publica. 2020;44:e57. doi:10.26633/RPSP.2020.57. Díaz-Madriz JP, et al. Impact of a pharmacist-driven antimicrobial stewardship program on the prescription of antibiotics by intensive care physicians in a Latin American hospital: a retrospective study. J Am Coll Clin Pharm. 2022;5(11):1148-55. doi:10.1002/jac5.1708. Domínguez I, et al. Evaluación del consumo de antimicrobianos en 15 hospitales chilenos: resultados de un trabajo colaborativo, 2013. Rev Chil Infectol. 2016 Jun;33(3):307-12. doi:10.4067/S0716-10182016000300010. ISSN 0716-1018. Ministerio de Salud de Chile. Norma general técnica N°210 para la racionalización del uso de antimicrobianos en la atención clínica. Resolución Exenta N°1146, 2020. Disponible en: https://diprece.minsal.cl/wp-content/uploads/2021/01/RES.-EXENTA-N%C2%B01146-Aprueba-Norma-Gral.-Te%CC%81cnica-N%C2%B00210-para-la-racionalizacio%CC%81n-del-uso-de-antimicrobianos-en-la-Atencio%CC%81n-Cli%CC%81nica_v2.pdf

On pourrait croire que le malheur frappe surtout les adolescents en crise ou les personnes âgées confrontées à la solitude. Pourtant, la science a une réponse surprenante. Une vaste étude publiée dans la revue PLOS One s'est penchée sur cette question en compilant des données colossales : plus de 10 millions d'Américains, 40 000 ménages britanniques et près de 2 millions de personnes issues de 44 pays différents. Un échantillon gigantesque, qui permet d'identifier une tendance universelle.Le résultat ? Le sentiment de mal-être n'atteint pas son sommet à l'adolescence, ni à la fin de la vie… mais vers l'âge de 47 ans.Les chercheurs parlent d'une véritable « courbe en U » du bonheur. Concrètement, la satisfaction de vie est relativement élevée chez les jeunes adultes, elle décline progressivement à mesure que l'on approche de la quarantaine, atteint un point bas autour de 47 ans, puis remonte dans la seconde partie de la vie. Autrement dit, beaucoup de personnes rapportent être plus heureuses à 60 ans qu'à 40.Pourquoi ce creux à la quarantaine ? Plusieurs explications sont avancées. C'est souvent l'âge des responsabilités maximales : charges familiales, pression professionnelle, dettes, fatigue accumulée. C'est aussi le moment où l'on mesure l'écart entre ses rêves de jeunesse et la réalité. Les chercheurs évoquent une sorte de « crise du milieu de vie », pas toujours visible mais largement ressentie.Après ce cap, les choses s'améliorent. Avec l'âge, les attentes deviennent plus réalistes, les pressions diminuent souvent, et beaucoup de personnes développent une meilleure gestion émotionnelle. C'est ce qui expliquerait la remontée du bien-être observée statistiquement après 50 ans.Il est intéressant de noter que cette courbe en U se retrouve dans presque toutes les cultures étudiées : qu'on vive aux États-Unis, en Europe, en Asie ou en Amérique latine, la tendance est la même. Cela suggère un mécanisme profondément ancré dans la trajectoire humaine, au-delà des différences sociales ou culturelles.Évidemment, il s'agit d'une moyenne : certaines personnes traversent leur quarantaine très heureuses, d'autres peuvent souffrir à d'autres âges. Mais sur le plan statistique, le pic de malheur se situe bien autour de la cinquantaine.Conclusion : si vous avez entre 45 et 50 ans et que vous vous sentez un peu moins heureux, sachez que vous n'êtes pas seul… et que la science promet des jours meilleurs : le bonheur remonte après ce cap. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Die Themen in den Wissensnachrichten +++ Lebenswichtige Systeme der Erde überlastet +++ Styropor mit Hilfe von Bakterium recycelt +++ Phänomen "Zoom-Fatigue" überschätzt? +++**********Weiterführende Quellen zu dieser Folge:Planetary Health Check 2025, Planetary Boundaries Science, 24.09.2025Biological upcycling of polystyrene into ready-to-use plastic monomers and plastics using metabolicallyBiological upcycling of polystyrene into ready-to-use plastic monomers and plastics using metabolically engineered Pseudomonas putida, Chemical Engineering Journal, 15.09.2025 engineered Pseudomonas putida, Chemical Engineering Journal, 15.09.2025First detection of Crimean Congo Hemorrhagic Fever antibodies in cattle and wildlife of southern continental France: Investigation of explanatory factors, Plos One, 24.09.2025Mummified cave Cheetah inform rewilding actions in Saudi Arabia, Research Square, 01.09.2025Volcanic crisis reveals coupled magma system at Santorini and Kolumbo, Nature, 24.09.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Le sexe nous fait transpirer, parfois même suer à grosses gouttes, mais cela ne veut pas forcément dire que ça suffit à éliminer le burger et la glace supplément chantilly du restau. Déjà en fonction de votre genre, la dépense énergétique pendant l'amour n'est pas la même.  D'après une étude publiée par la revue Plos One, les hommes brûlent en moyenne 101 calories et les femmes 69 calories au cours d'un rapport sexuel de 25 minutes. Un homme et une femme ne brûlent pas autant ? Les calories brûlées dépendent du type de rapport sexuel ? Mais pourquoi on transpire autant alors si ce n'est pas un effort intense ?  Un podcast Bababam Originals, écrit et réalisé par Laura Taouchanov. À écouter aussi : Qui sont ces stars accros au sexe ? Quels sont les secrets des scènes de sexe au cinéma ? Addiction au sexe : comment la dépister ? Suivez Bababam sur ⁠⁠⁠Instagram⁠⁠⁠. Learn more about your ad choices. Visit megaphone.fm/adchoices

Chegou o momento do já tradicional episódio duplo sobre o IgNobel, que tem como missão "honrar estudos e experiências que primeiro fazem as pessoas rir e depois pensar", com as descobertas científicas mais estranhas do ano.Esta é a primeira de duas partes sobre a edição 2025 do prêmio, com as categorias Literatura, Psicologia, Nutrição, Biologia e Química.Confira no papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.> OUÇA (52min 22s)*Naruhodo! é o podcast pra quem tem fome de aprender. Ciência, senso comum, curiosidades, desafios e muito mais. Com o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.Edição: Reginaldo Cursino.http://naruhodo.b9.com.br*APOIO: INSIDERIlustríssima ouvinte, ilustríssimo ouvinte do Naruhodo,sabe qual a minha peça coringa no guarda-roupas?É a Camiseta Oversized T-Shirt da INSIDER.Trampo? Ela cai bem.Lazer? Ela cai muito bem.É macia.É elástica.É anti-odor.Não desbota com o tempo.Não precisa passar.Regula a temperatura corporal.Entendeu por que ela é minha peça coringa?E, em Setembro, o Mês do Cliente, você tem a melhor oportunidade para começar a comprar INSIDER: combinando o cupom NARUHODO com os descontos do site, o seu desconto total pode chegar a até 50%!Isso mesmo: sua compra pode sair até pela metade do preço.Mas tem que acessar pela URL especial:creators.insiderstore.com.br/NARUHODOOu clicar no link da descrição deste episódio:o cupom será aplicado automaticamente no carrinho.INSIDER: inteligência em cada escolha.#InsiderStore*REFERÊNCIASThe 35th First Annual Ig Nobel Ceremony (2025)https://www.youtube.com/watch?v=z1cP4xKd_L4PRÊMIO DE LITERATURA [EUA]O falecido Dr. William B. Bean, por registrar e analisar persistentemente, durante 35 anos, a taxa de crescimento de uma de suas unhas. “A Note on Fingernail Growth,” William B. Bean, Journal of Investigative Dermatology, vol. 20, no. 1, January 1953, pp. 27-31. “A Discourse on Nail Growth and Unusual Fingernails,” William B. Bean, Transactions of the American Clinical and Climatological Association, vol. 74, 1962; pp. 152-67. “Nail Growth. Twenty-Five Years' Observation,” William B. Bean, Archives of Internal Medicine, vol. 122, no. 4, October 1968, pp. 359-61. “Nail Growth: 30 Years of Observation,” William B. Bean, Archives of Internal Medicine, vol. 134, no. 3, September 1974, pp. 497-502. “Some Notes of an Aging Nail Watcher,” William B. Bean, International Journal of Dermatology, vol. 15, no. 3, April 1976, pp. 225-30. “Nail Growth. Thirty-Five Years of Observation,” William B. Bean, Archives of Internal Medicine, vol. 140, no. 1, January 1980, pp. 73-6.  Vreeman, R. C; Carroll, A. E (2007). "Medical myths". BMJ. 335 (7633): 1288–9. doi:10.1136/bmj.39420.420370.25PRÊMIO DE PSICOLOGIA [POLÔNIA, AUSTRÁLIA, CANADÁ]Marcin Zajenkowski e Gilles Gignac, por investigarem o que acontece quando você diz a pessoas narcisistas — ou a qualquer outra pessoa — que elas são inteligentes. “Telling People They Are Intelligent Correlates with the Feeling of Narcissistic Uniqueness: The Influence of IQ Feedback on Temporary State Narcissism,” Marcin Zajenkowski and Gilles E. Gignac, Intelligence, vol. 89, November–December 2021, 101595.  PRÊMIO DE NUTRIÇÃO [NIGÉRIA, TOGO, ITÁLIA, FRANÇA]Daniele Dendi, Gabriel H. Segniagbeto, Roger Meek e Luca Luiselli, por estudarem em que medida um certo tipo de lagarto escolhe comer certos tipos de pizza. “Opportunistic Foraging Strategy of Rainbow Lizards at a Seaside Resort in Togo,” Daniele Dendi, Gabriel H. Segniagbeto, Roger Meek, and Luca Luiselli, African Journal of Ecology, vol. 61, no. 1, 2023, pp. 226-227.  PRÊMIO DE BIOLOGIA [JAPÃO]Tomoki Kojima, Kazato Oishi, Yasushi Matsubara, Yuki Uchiyama, Yoshihiko Fukushima, Naoto Aoki, Say Sato, Tatsuaki Masuda, Junichi Ueda, Hiroyuki Hirooka e Katsutoshi Kino, por seus experimentos para descobrir se vacas pintadas com listras semelhantes às de zebras podem evitar ser picadas por moscas. “Cows Painted with Zebra-Like Striping Can Avoid Biting Fly Attack,” Tomoki Kojima, Kazato Oishi, Yasushi Matsubara, Yuki Uchiyama, Yoshihiko Fukushima, Naoto Aoki, Say Sato, Tatsuaki Masuda, Junichi Ueda, Hiroyuki Hirooka, and Katsutoshi Kino, PLoS ONE, vol. 14, no. 10, 2019, e0223447.  PRÊMIO DE QUÍMICA [EUA, ISRAEL]Rotem Naftalovich, Daniel Naftalovich e Frank Greenway, por experimentos para testar se comer Teflon [uma forma de plástico mais formalmente chamada “politetrafluoretileno”] é uma boa maneira de aumentar o volume do alimento e, portanto, a saciedade sem aumentar o conteúdo calórico. “Polytetrafluoroethylene Ingestion as a Way to Increase Food Volume and Hence Satiety Without Increasing Calorie Content,” Rotem Naftalovich, Daniel Naftalovich, and Frank L. Greenway, Journal of Diabetes Science and Technology, vol. 10, no. 4, July 2016, pp. 971–976. “Use of Nondigestible Nonfibrous Volumizer of Meal Content as a Method for Increasing Feeling of Satiety,” Rotem Naftalovich  and Daniel Naftalovich, U.S. Patent 9,924,736, issued March 27, 2018.  *APOIE O NARUHODO!O Altay e eu temos duas mensagens pra você.A primeira é: muito, muito obrigado pela sua audiência. Sem ela, o Naruhodo sequer teria sentido de existir. Você nos ajuda demais não só quando ouve, mas também quando espalha episódios para familiares, amigos - e, por que não?, inimigos.A segunda mensagem é: existe uma outra forma de apoiar o Naruhodo, a ciência e o pensamento científico - apoiando financeiramente o nosso projeto de podcast semanal independente, que só descansa no recesso do fim de ano.Manter o Naruhodo tem custos e despesas: servidores, domínio, pesquisa, produção, edição, atendimento, tempo... Enfim, muitas coisas para cobrir - e, algumas delas, em dólar.A gente sabe que nem todo mundo pode apoiar financeiramente. E tá tudo bem. Tente mandar um episódio para alguém que você conhece e acha que vai gostar.A gente sabe que alguns podem, mas não mensalmente. E tá tudo bem também. Você pode apoiar quando puder e cancelar quando quiser. O apoio mínimo é de 15 reais e pode ser feito pela plataforma ORELO ou pela plataforma APOIA-SE. Para quem está fora do Brasil, temos até a plataforma PATREON.É isso, gente. Estamos enfrentando um momento importante e você pode ajudar a combater o negacionismo e manter a chama da ciência acesa. Então, fica aqui o nosso convite: apóie o Naruhodo como puder.bit.ly/naruhodo-no-orelo

Stress isn't just something to “manage” — it's a signal, a teacher, and often, an invitation to look deeper at our health, our choices, and our lives. In this solo episode, Darin reframes stress not as an enemy, but as a dashboard light pointing toward misalignments in our nervous system, environment, relationships, and purpose. Drawing on science, practical tools, and personal insight, Darin reveals how layered stress silently drains our vitality — and how to transform it into an ally for growth, healing, and deeper contentment. Whether it's hidden trauma, toxic environments, unresolved conflict, or the modern distractions constantly pulling at our attention, Darin lays out a roadmap to stop the leaks and reclaim the energy already within you. This episode is a powerful reminder: stress isn't the end of the story — it's the beginning of awareness, safety, and a super life.     What You'll Learn in This Episode [00:00] Introduction to the Super Life podcast [03:27] Why stress might not be your enemy [04:17] Stress as an ally: the signals it gives us about misalignment [04:32] The dashboard light metaphor: how stress reveals hidden issues [05:28] The illusion of “no choice” and the infinite possibilities always available [06:12] Global stress statistics and why most people underestimate their stress load [07:23] Hidden stress revealed through heart rate variability and physiology [08:23] Layered stress: how sleep, exercise, and poor choices compound each other [09:25] Safety vs. calm — why your nervous system craves safety first [10:15] Trauma and the unconscious mind: how old wounds drive our stress response [11:54] Inner narratives and negative self-talk as hidden stress multipliers [12:22] The role of community and your social field in stress and resilience [13:53] Relationships, honesty, and how your circle shapes your energy [14:55] Why boundaries around media and politics are vital for mental clarity [17:42] Finding micro-purpose when life feels overwhelming [18:52] Environmental layers of stress — light, air, and clutter [19:15] The existential layer: stress from living without service or purpose [20:12] Stress as a risk amplifier — how it undermines healing and health [20:55] The deeper truth of safety, connection, and higher power [23:00] Practical tools: breathing, grounding, nature, and conscious choices [24:01] Trauma reframed: not a problem, but a protector at the time [25:25] Lessons from Peter Levine and wild animals: releasing trauma physically [26:04] Questions to ask trauma: “What are you protecting me from?” [26:56] Stress as a multiplier of aging, disease, and poor outcomes [29:20] Why stress isn't a single cause — it's layered and chronic [30:18] Anti-stress strategies: circadian rhythm, nature, and gratitude [31:49] Energy leaks to avoid: clutter, poor food, scrolling, bad boundaries [32:22] What matters most: service, contribution, and alignment [33:28] Final toolkit: breathwork, movement, nature, sleep, and gratitude [34:38] The deeper invitation: step into sovereignty and live your SuperLife     Thank You to Our Sponsors: Manna Vitality: Go to mannavitality.com/  or use code DARIN20 for 20% off your order. Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Check out my podcast with Dr. Amy Abbington     Key Takeaway “Stress is not the enemy. It's a dashboard light — a teacher showing you where you're out of alignment. When you reframe stress, you reclaim your energy and create space for healing, safety, and the joy of living a super life.”     Bibliography (selected, peer-reviewed) Sources: Gallup Global Emotions (2024); Gallup U.S. polling (2024); APA Stress in America (2023); Natarajan et al., Lancet Digital Health (2020); Orini et al., UK Biobank (2023); Martinez et al. (2022); Leiden University (2025). Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med.1991;325(9):606–612. New England Journal of Medicine Cohen S, et al. Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. Proc Natl Acad Sci USA. 2012;109(16):5995–5999. PNAS Kiecolt-Glaser JK, et al. Slowing of wound healing by psychological stress. Lancet. 1995;346(8984):1194–1196. The Lancet Kiecolt-Glaser JK, et al. Hostile marital interactions, proinflammatory cytokine production, and wound healing.Arch Gen Psychiatry. 2005;62(12):1377–1384. JAMA Network Tawakol A, et al. Relation between resting amygdalar activity and cardiovascular events. Lancet.2017;389(10071):834–845. The Lancet Epel ES, et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA.2004;101(49):17312–17315. PNAS McEwen BS, Stellar E. Stress and the individual: mechanisms leading to disease. Arch Intern Med.1993;153(18):2093–2101. PubMed McEwen BS, Wingfield JC. Allostasis and allostatic load. Ann N Y Acad Sci. 1998;840:33–44. PubMed Felitti VJ, et al. Relationship of childhood abuse and household dysfunction to many leading causes of death in adults (ACE Study). Am J Prev Med. 1998;14(4):245–258. AJP Mon Online Edmondson D, et al. PTSD and cardiovascular disease. Ann Behav Med. 2017;51(3):316–327. PMC Afari N, et al. Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis.Psychosom Med. 2014;76(1):2–11. PMC Goyal M, et al. Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Intern Med. 2014;174(3):357–368. PMC Qiu Q, et al. Forest therapy: effects on blood pressure and salivary cortisol—a meta-analysis. Int J Environ Res Public Health. 2022;20(1):458. PMC Laukkanen T, et al. Sauna bathing and reduced fatal CVD and all-cause mortality. JAMA Intern Med.2015;175(4):542–548. JAMA Network Zureigat H, et al. Physical activity lowers CVD risk by reducing stress-related neural activity. J Am Coll Cardiol.2024;83(16):1532–1546. PMC Holt-Lunstad J, Smith TB, Layton JB. Social relationships and mortality risk: a meta-analytic review. PLoS Med.2010;7(7):e1000316. PMC Chen Y-R, Hung K-W. EMDR for PTSD: meta-analysis of RCTs. PLoS One. 2014;9(8):e103676. PLOS Hoppen TH, et al. Network/pairwise meta-analysis of PTSD psychotherapies—TF-CBT highest efficacy overall.Psychol Med. 2023;53(14):6360–6374. PubMed van der Kolk BA, et al. Yoga as an adjunctive treatment for PTSD: RCT. J Clin Psychiatry. 2014;75(6):e559–e565. PubMed Kelly U, et al. Trauma-center trauma-sensitive yoga vs CPT in women veterans: RCT. JAMA Netw Open.2023;6(11):e2342214. JAMA Network Bentley TGK, et al. Breathing practices for stress and anxiety reduction: components that matter. Behav Sci (Basel). 2023;13(9):756. 

Die Themen in den Wissensnachrichten: +++ Schimpansen fressen pro Tag vergorene Früchte mit so viel Alkohol wie zwei kleine Biere +++ Konrad-Adenauer-Stiftung rät zum Aufrechterhalten der Brandmauer +++ Globaler Wasserhaushalt immer unberechenbarer +++**********Weiterführende Quellen zu dieser Folge:Ethanol ingestion via frugivory in wild chimpanzees, Science Advances, 17.09.2025Zwischen Abgrenzung, Einbindung und Tolerierung. Fallbeispiele für den Umgang mit rechtspopulistischen Parteien in Europa, Konrad-Adenauer-Stiftung, 18.09.2025State of Global Water Resources 2024, WMO, 18.09.2025Microscopic geared metamachines, Nature Communications, 20.08.2025More than just one man and his dog: The many impacts of puppy acquisition on the mental health of families including children in the UK, Plos One, 17.09.2025**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

In the latest episode of Making Cents of Money, learn about the habits that can impact your financial decisions and how stress plays a role in spending. Show Notes: American Psychological Association. (2015, February 4). American Psychological Association survey shows money stress weighing on Americans' health nationwide. Retrieved from https://www.apa.org/news/press/releases/2015/02/money-stress American Psychological Association. (2023). Stress in America 2023: A nation recovering from collective trauma. Retrieved from https://www.apa.org/news/press/releases/2023/03/stress-in-america Falconier, M. K., & Epstein, N. B. (2011). Couples experiencing financial strain: What we know and what we can do. Family Relations, 60(3), 303–317. Gelman, A., & Kliger, D. (2021). Effect of time-induced stress on financial decision making in real markets. PloS One, 16(11), e0123740. Heo, W., Cho, S. H., & Lee, P. (2020). APR Financial Stress Scale: Development and validation of a multidimensional measurement. Journal of Financial Therapy, 11(1), 2. https://newprairiepress.org/jft/vol11/iss1/2/ Lazarus, R. S., & Folkman, S. (1984). Stress, appraisal, and coping. Springer Publishing Company. Narayan, A. (2024). The impact of financial stress on workplace harassment and discrimination. Management Science, 70(4), 2447–2458. Ong, A. D., Sturgeon, J. A., Arewasikporn, A., Okun, M. A., Davis, M. C., & Zautra, A. J. (2015). The psychosocial context of financial stress: Implications for inflammation and psychological health. Psychosomatic Medicine, 77(2), 187–194. Porcelli, A. J., & Delgado, M. R. (2009). Acute stress modulates risk taking in financial decision making. Psychological Science, 20(3), 278–285. Shafir, E., Mullainathan, S., & Shafir, E. (2013). Scarcity: Why having too little means so much. Times Books. Van Boven, L., & Gilovich, T. (2003). To do or to have? That is the question. Journal of Personality and Social Psychology, 85(6), 1193–1202. Wilke, J., & Boden, J. M. (2021). Financial scarcity and financial avoidance: A prospective study. Journal of Economic Psychology, 87, 102408. Mental Health Crisis Resources: Illinois Department of Central Management Services' Crisis Resources: https://cms.illinois.gov/benefits/stateemployee/bewell/mental-health/crisis.html Relevant Podcast Episodes: • Money in Relationships: https://soundcloud.com/idfpr/money-and-relationships • Financial Socialization: https://soundcloud.com/idfpr/episode-99-financial-socialization • Investing: https://soundcloud.com/idfpr/episode-57-investing-to-reach-financial-goals • Budgeting: https://soundcloud.com/idfpr/mcom-ep20-budgeting-final • Probably Inflation: https://soundcloud.com/idfpr/episode-30-inflation

Die Themen in den Wissensnachrichten: +++ Oktopusse bevorzugen bestimmte Arme +++ Schlafmangel lässt das Gehirn womöglich schneller altern +++ Blaues Licht macht Wäsche sauber +++**********Weiterführende Quellen zu dieser Folge:Octopus arm flexibility facilitates complex behaviors, Nature, 11.09.2025Associations of Chronic Insomnia, Neurology, 7.10.2025Environmentally Friendly Photobleaching Method, ACS, 1.8.2025A Late Bronze Age foreign elite? Investigating mobility patterns, Plos One, 10.09.2025Deutscher Umweltpreis 2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

In this solo episode, Darin shares everything he's learned over nearly a decade of caring for his beloved German Shepherds, Chugga and Ella. From water quality to food choices, stress management, natural therapies, and even stem cells, Darin reveals the daily practices and integrative care strategies that keep his dogs thriving. With inspiration from Forever Dog authors Rodney Habib and Dr. Karen Becker, this episode is packed with actionable steps and powerful reminders about what it means to be a true steward for our animal companions. What You'll Learn in This Episode [00:00] Welcome and introduction – why this episode is dedicated to dogs and animal care [00:40] The bond with Chugga and Ella and why stewardship matters [01:16] Inspiration from The Forever Dog and leading longevity experts [01:38] Clean water: why filtration is critical for pets and how Darin prepares it [03:01] How much water your dog really needs and the danger of dehydration [03:38] A scary heatstroke story with Ella and the importance of paying attention [04:11] Daily care tips: washing bowls, using stainless steel, and avoiding bacteria buildup [04:43] Electrolytes, minerals, and using natural supplementation for dogs' hydration [05:35] Food choices: balancing plant-based with raw diets using Bramble and Viva Raw [07:01] The Dog Aging Project: why feeding once a day may extend longevity [08:12] Transitioning from kibble to raw: microbiome, gut diversity, and safety tips [09:47] Adding veggies, pumpkin, sweet potatoes, and berries for diversity and antioxidants [11:40] The importance of walks, exercise, and letting dogs sniff for cognitive health [12:27] Training, discipline, and running with Chugga on the mountain bike [13:32] How dogs mirror our stress and why managing your own health impacts theirs [14:01] Working with the endocannabinoid system, CBD, and reducing nervous tension [15:03] Natural therapies: PEMF mats, AmpCoil, red light, and energy balancing [16:08] Conventional vs naturopathic care—when to use both for acute and long-term health [17:00] Chugga's autoimmune challenges and the integrative approach to healing [18:20] Modalities used: stem cells, acupuncture, microbiome testing, ozone baths, and more [20:34] How pets reflect back our stress and why healing ourselves heals them too [22:07] Building a holistic health protocol: food, supplements, exercise, trauma release [23:05] Why meal timing and fasting windows can boost detox and longevity in dogs [25:11] Daily practices: washing bowls, diversifying food, hydration, and routines [26:29] The role of the endocannabinoid system in pets and humans alike [27:27] Alternative therapies: psychic readings, EFT, remote healing, and staying open [28:10] Back to basics: food, water, exercise, sleep, and trauma release for pets and people [28:41] Final reflections: stewardship, love, and why pets are free beings bonded to us Thank You to Our Sponsors: Our Place: Toxic-free, durable cookware that supports healthy cooking. Use code DARIN for 10% off at fromourplace.com. Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway “Our dogs are barometers for our own well-being. When we reduce toxins, diversify food, manage stress, and honor them as family, they not only thrive longer — they remind us how to live better ourselves.” Bibliography / Sources Water & nutrition guidance WSAVA Global Nutrition—pet food selection & toolkit; Merck Veterinary Manual—typical daily water needs. WSAVA+1MSD Veterinary Manual Feeding frequency Bray EE et al. “Once-daily feeding is associated with better health in companion dogs” (Dog Aging Project, GeroScience 2022). PMCPubMedDog Aging Project Activity & cognition Dog Aging Project analyses on physical activity and cognitive health in older dogs (GeroScience 2022). ResearchGate Raw diets: microbiome & safety Sandri M. et al., BMC Vet Res 2016; Schmidt M. et al., PLOS ONE 2018; Xu J. et al., 2021; Davies RH. et al., 2019 (review on raw diets & pathogens). BioMed CentralPLOSPMC+1 Plant-based diets for dogs Knight A. et al., PLOS ONE 2022. PMC Microbiome testing (clinical tool) Texas A&M GI Lab—Dysbiosis Index overview. AVMA Owner–dog connection, stress & oxytocin Roth L. et al., Scientific Reports 2019 (stress synchrony); Wilson C. et al., PLOS ONE 2022 (dogs smell human stress); Nagasawa M. et al., Science 2015 (oxytocin gaze loop). NaturePMCPubMed Stem cells for canine OA Harman R. et al., Front Vet Sci 2016 (RCT, allogeneic ADSCs); Cuervo B. et al., Int J Mol Sci 2014 (randomized); VetEvidence 2022 (knowledge summary). FrontiersPMCVeterinary Evidence Acupuncture / gold bead studies & reviews Baker-Meuten A. et al., 2020 (prospective OA); Teixeira LR. et al., JAVMA 2016; Jaeger GT. et al., Vet Rec 2006. PMCAVMA JournalsPubMed Photobiomodulation (red light) AVMA Journals RCT in canine hip OA (2022). DVM 360 PEMF Randomized post-op pain/IVDD trial (NC State coverage); Front Vet Sci 2021 (targeted PEMF). NC State NewsFrontiers Chiropractic / manipulation Randomized Boxer puppy study (spondylosis); systematic review of manipulative therapies; AVMA policy context. PMC+1AVMA Ozone & IV Vitamin C Veterinary ozone therapy reviews (limited evidence); Merck Vet Manual—dogs synthesize vitamin C (routine IV-C not standard).  

In this BTP Short, Dr. Dewey Caron shares another of his “audio postcards,” this time exploring the critical role of fat bees—also known as diutinus bees—in helping colonies survive winter. Dewey explains how these long-lived worker bees differ from their summer sisters, with enlarged fat bodies, higher protein reserves, and lower juvenile hormone levels, all tied to the key blood protein vitellogenin. Drawing on published research papers, Dewey highlights how environmental cues such as declining pollen, temperature, and daylight trigger the production of winter bees, and how clustering helps colonies thermoregulate through the cold months. He emphasizes that strong, heavy colonies going into winter are far more likely to survive than weak or light ones. For beekeepers, Dewey stresses the importance of continuous Varroa control throughout the season, fall feeding to ensure sufficient carbohydrate and protein stores, and combining weaker units when necessary. He also discusses drone eviction, stock influences, and climate change modeling that suggests warmer falls may disrupt the balance of winter bee production and survival. This episode provides science-based insights and practical recommendations to help beekeepers communicate with their colonies—ensuring not only fat bees, but fat, well-prepared colonies for overwintering success. Websites and Links mention in the episode: Döke, Mehmet A. M. Frazier, and C.  Grozinger, 2015 “Overwintering honey bees: biology and management,” Current Opinion in Insect Science. Mehmet Ali Döke, Christina M. Grozinger. 2017. Pheromonal control of overwintering physiology and success in honey bees (Apis mellifera, L.) Döke, Mehmet Ali, CM McGrady, M. Otieno, CM Grozinger, M Frazier. 2019. Colony size, rather than geographic origin of stocks, predicts overwintering success in honey bees (Hymenoptera: Apidae) in the Northeastern United States. J. Econ. Entomology 112 (2), 525-533, DOI: 10.1093/jee/toy377 Stephanie Feliciano-Cardona, †Mehmet Ali Döke, Janpierre Ale man,Jose Luis Agosto-Rivera. Christina M. Grozinger and Tugrul Giray 2020. Honey Bees in the Tropics Show Winter Bee-Like Longevity in Response to Seasonal Dearth and Brood Reduction. Front. Ecol. Evol., 8.  https://doi.org/10.3389/fevo.2020.571094 Somerville, Doug (2005) Fat Bees Skinny Bees, A manual on honey bee nutrition for beekeepers., Australia. Available on the Web at https://www.agrifutures.com.au/wp-content/uploads/publications/05-054.pdf   https://rirdc.infoservices.com.au/downloads/05-054 Kirti Rajagopalan, Gloria DeGrandi-Hoffman, Matthew Pruett, Vincent P. Jones, Vanessa Corby-Harris, Julien Pireaud, Robert Curry, Brandon Hopkins & Tobin D. Northfield. 2024. Warmer autumns and winters could reduce honey bee overwintering survival with potential risks for pollination services. Scientific Reports volume 14, Article number: 5410 (2024) For homework Ashley L. St. Clair , Nathanael J. Beach, Adam G. Dolezal. 2022.  Honey bee hive covers reduce food consumption and colony mortality during overwintering. Plos One. https://doi.org/10.1371/journal.pone.0266219  SBGM videos:  https://mail.google.com/mail/u/0/#inbox/FMfcgzQcpKmXBhglCpthGSBzvHVLlSfp   Brought to you by Betterbee – your partners in better beekeeping. ______________ Betterbee is the presenting sponsor of Beekeeping Today Podcast. Betterbee's mission is to support every beekeeper with excellent customer service, continued education and quality equipment. From their colorful and informative catalog to their support of beekeeper educational activities, including this podcast series, Betterbee truly is Beekeepers Serving Beekeepers. See for yourself at www.betterbee.com Copyright © 2025 by Growing Planet Media, LLC

Welcome to Episode 272 of Autism Parenting Secrets.This week, we're talking about a medicine almost every parent has used. For decades, doctors have recommended it for fevers, ear infections, even after vaccines. It's long been considered safe.But compelling evidence shows it's not nearly as safe as we've been told—especially for babies and young children under stress.My guest is Dr. William Parker. He is distinguished, highly credentialed, and deeply passionate about protecting children. After earning his PhD in Chemistry, he spent nearly 30 years at Duke University studying biochemistry, microbiology, and immunology. He's best known for discovering the function of the human appendix—a safe-house for bacteria—and for the last decade, he's focused on how acetaminophen, when combined with oxidative stress, impacts brain development. He's published more than 150 peer-reviewed papers, and his work points to this drug playing a major role in the rise of autism.This is a conversation parents need to hear. Dr. Parker is substantive, credible, and unwavering in his pursuit of the truth. It's not about fear—it's about clarity and better choices.The secret this week is…AVOID THIS Popular Drug To Protect DevelopmentYou'll Discover:The Hidden Link First Exposed in 2008 (4:51)How Acetaminophen + Oxidative Stress = Trouble For Susceptible Kids (15:29)The Timeline That Matches The Rise of Autism (23:26)The Flawed Assumptions in Many Scientific Studies (26:50)Practical Next Steps Parents Can Take (45:53)The Actual MECHANISM That Harms Brain Cells (51:07)About Our Guest:William Parker earned a PhD in Chemistry in 1992 and studied biochemistry, microbiology, and immunology at Duke University for almost 30 years before starting WPLab, a private, non-profit research and education corporation, in 2021. Best known for the discovery of the function of the human appendix (a safe-house for bacteria), Dr. Parker has spent almost a decade studying the impact of acetaminophen combined with oxidative stress on neurodevelopment. He has published more than 150 peer-reviewed papers, including work in PLoS One, the European Journal of Pediatrics, Minerva Pediatrics, and Clinical and Experimental Pediatrics. WPLab scientists have concluded that many, if not most, cases of autism are a chemically induced injury caused by exposure of susceptible babies and children to acetaminophen.References In This Episode:Learn more about Dr. Parker's work: PreventAutism.org and www.wplaboratory.orgAdditional Resources:To learn more about personalized 1:1 support, go to www.elevatehowyounavigate.comTake The Quiz: What's YOUR Top Autism Parenting Blindspot?If you enjoyed this episode, share it with your friends.

Saviez-vous que nos ancêtres Homo sapiens utilisaient déjà des teintures végétales il y a 34 000 ans ? Dans cet épisode captivant du podcast ArtEcoVert, nous avons le plaisir d'accueillir Pauline Leroux, ingénieure agronome passionnée par la couleur végétale et les plantes tinctoriales. Ensemble, nous plongeons dans une découverte archéologique fascinante qui remet en question notre compréhension des capacités créatives de nos ancêtres. Pauline nous fait découvrir une étude récente publiée dans la revue PLOS ONE, qui met en lumière des résidus de guède retrouvés dans la grotte de Dzudzuana, en Géorgie. Ces résidus, contenant de l'indigotine, prouvent que ces hommes préhistoriques savaient transformer les feuilles en couleurs, un processus chimique complexe qui nécessite observation et expérimentation. Cette révélation nous pousse à réfléchir à la manière dont la teinture végétale, qu'elle soit à base d'indigo, de garance, ou d'autres colorants biosourcés, a façonné notre rapport à l'art et à la couleur. Pauline souligne que cette quête d'esthétisme et de sens ne se limitait pas à la survie, mais s'étendait à une véritable exploration des nuances et des pigments végétaux. Comment ces pratiques anciennes influencent-elles notre compréhension de la couleur et de l'art aujourd'hui ? En écoutant cet épisode, vous découvrirez l'importance des fibres naturelles et des tanins dans la création de colorants végétaux, ainsi que l'impact de l'agriculture tinctoriale sur notre environnement et nos jardins. Ne manquez pas cette occasion d'approfondir vos connaissances sur les plantes tinctoriales et leur rôle dans notre histoire culturelle. Que vous soyez un passionné de couleur, un amateur d'art ou simplement curieux d'en savoir plus sur les trésors que nous offre le monde végétal, cet épisode d'ArtEcoVert est fait pour vous. Pour en savoir plus sur les sujets abordés, consultez les liens utiles dans la description. Belle écoute et laissez-vous inspirer par la voix de la couleur végétale avec Pauline ! ArtEcoVert informe et inspire celles et ceux qui veulent repenser la couleur autrement, et les accompagne dans leur transition vers une couleur plus durable — avec des témoignages concrets le jeudi

Episode 202: BPA OverviewWritten by Cameron Carlisle, MSIV, Ross University School of Medicine. Comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice._____________________Arr: Welcome to another episode of Rio Bravo qWeek. My name is Hector Arreaza, I'm an associate program director and faculty in the Rio Bravo Family Medicine Residency Program. Today my co-host is Cameron Carlisle, who is a 4th-year medical student finishing his last rotation of med school. Welcome, Cameron, please introduce yourself.Arreaza: What are we talking about today, Cameron?Cam: Dr. Arreaza, did you know you're probably carrying around a chemical in your body that mimics estrogen? In fact, a 2004 CDC study found over 92% of Americans had detectable levels of Bisphenol A (BPA) in their urine. Today's topic is BPA.BPA is everywhere: receipts, water bottles, canned foods, baby bottles, and even our dental fillings. It's one of the most ubiquitous endocrine-disrupting chemicals (EDCs), which interferes with the body's hormone systems. That's why today's episode is about making the invisible visible. Our goals for today's podcast:Break down what BPA isShow how it affects the human bodyExplain how you and your patients can limit exposureEmpower both clinicians and the public with real, practical informationArreaza: Thanks for clarifying BPA today. It seems like we always have to learn about a new carcinogen or toxic substance that we are exposed to. I remember when I was a child, Yellow #5 became very concerning for the general public but it is still being used in our foods. So, it's good you are talking about this. What Is BPA?Cam: Bisphenol A (BPA) is an industrial chemical used since the 1950s, primarily in polycarbonate plastics and epoxy resins. It makes plastic clear, and is often found in:Water bottlesCanned food liningsBaby bottles (pre-2012)Takeout containersCash register receiptsDental sealantsArreaza: So, I've seen the “BPA-free” labels many times, and today I'm glad you are going to shed some light about it.Cam: What's alarming is that BPA leaches out of these products, especially when exposed to heat, acidity, or repeated use. A Harvard study found that people who drank from plastic bottles for just one week had a 69% increase in urinary BPA levels (Carwile & Michels, 2009).Arreaza: That's a lot of people 69%. Section 3: What happens when BPA gets into our body? How BPA Works in the BodyCam: BPA is classified as an endocrine disruptor, meaning it can bind to estrogen receptors and mimic or block natural hormone functions.It affects:Reproductive systems (both male and female)NeurodevelopmentThyroid signalingPancreatic β-cell functionMetabolism and fat storageEven low-dose exposure can disrupt cellular function. BPA acts as a xenoestrogen (foreign estrogen) and has been shown to alter DNA methylation, leading to epigenetic changes that persist across generations (Manikkam et al., 2013).Arreaza: So, BPA can cause epigenetic changes that can be inherited. BPA can persist for generations in your offspring.BPA's Health Impacts – What the Research SaysHere's where it gets serious. Let's go system-by-system:1. Reproductive HealthFemales: Linked to PCOS, infertility, and early puberty (Peretz et al., 2014).Males: Reduced sperm count and motility; altered testosterone levels.2. Pregnancy and Birth OutcomesIncreased risk of preterm birth, gestational diabetes, and low birth weight (Snijder et al., 2013).Studies show BPA crosses the placenta, directly affecting the fetus.3. Neurological DevelopmentAssociated with ADHD, anxiety, and impaired executive function in children exposed in utero (Mustieles et al., 2015).4. Metabolism and DiabetesBPA exposure is linked to insulin resistance, obesity, and type 2 diabetes, even at low doses (Lang et al., 2008).5. CancerAnimal and human data link BPA to increased risk of breast and prostate cancer via estrogenic mechanisms.6. MortalityA 2020 JAMA study found individuals with higher BPA levels had a 49% increased risk of all-cause mortality compared to those with lower levels (Gao et al., 2020).Arreaza: You are scaring me. I wonder what my BPA level is in my blood. Actually, BPA can be detected in urine. This is the most common approach for population-level biomonitoring, because BPA and its metabolites are mostly excreted in urine. Studies have found that BPA is present in most people, even up to 85–99% in large cohorts. Cam: That's literally everyone. Sources of BPA ExposureLet's talk about things we use every day:Thermal receipts (like from Target or Starbucks): BPA can transfer onto your skin and be absorbed, especially if your hands are wet or lotioned.Canned soups: One study showed that eating canned soup daily for five days led to a 1000% increased urinary BPA levels (Carwile et al., 2011).Plastic water bottles left in the car on hot days or plastic food trays for microwaving = chemical leaching.Baby bottles and pacifiers (pre-2012): primary concern for newborns.Arreaza: So, Cameron, you were exposed to BPA as a baby.Cam: Here's the jaw-dropper: We ingest up to 5 grams of plastic per week, roughly the weight of a credit card (WWF, 2019; University of Newcastle). This includes microplastics like BPA, which enter through food, water, and air.Arreaza: So, it translates into 40 lbs of plastic in a lifetime, by age 70. What can we do as family physicians?Family Medicine and Preventive CareAs family physicians, we are at the frontlines of prevention. Our role includes:Anticipatory guidance: during prenatal visits, well-child visits, and chronic disease managementScreening opportunities: ask about storage habits, microwave use, and receipt handlingEnvironmental health counseling: AAFP recommends addressing endocrine disrupting chemicals (EDCs) when relevant to a patient's concerns.It's not just about treating diabetes or obesity. It's about recognizing that environmental exposure may be a root cause.Arreaza: Prevention is my favorite topic!Cam: One helpful clinical practice:Arreaza: What else can we do to reduce BPA exposure?Practical Steps to Reduce BPAHere's what patients and doctors alike can do today:Switch to BPA-free products, but be careful, as replacements like BPS or BPF may also be harmful (Rochester & Bolden, 2015).Avoid microwaving or dishwashing plastic containers.Use digital receipts.Filter tap water using carbon filters, which can reduce microparticle ingestion.Choose fresh produce over canned goods when possible.Also, wash your hands after handling receipts, especially before eating or touching your face.Arreaza: What is our government doing to protect us?Public Health and Policy UpdatesRegulations are slowly catching up:The FDA banned BPA in baby bottles and sippy cups in 2012.The European Union has stricter limits, and France banned BPA in all food packaging in 2015.California's Proposition 65 requires BPA warning labels.Arreaza: Proposition 65, passed by direct voter initiative in 1986, “WARNING: This product contains chemicals known to the State of California to cause cancer and birth defects or other reproductive harm.”Arreaza: The FDA is planning to phase out petroleum-based food dyes (certified color additives) from the American food supply – marking a significant milestone in the efforts to protect the public. Cam: Many products still contain BPA analogs (BPS, BPF), which are not yet well-regulated.This is where clinician advocacy matters, where we can guide public opinion and support legislative change.Arreaza: So, millions of pounds of toxic substances are produced by many industries in the US. As physicians, we have to stay informed and update our patients.Cameron: How can we wrap up this episode?Conclusion and TakeawaysBPA is a hormone disruptor hiding in plain sight.People are exposed to BPA every day, but small lifestyle changes can dramatically reduce it.Family medicine has a role in education, prevention, and advocacy.Let's all be part of the solution for our health and future generations. Stanley (tumblers) are not sponsoring this episode, and we did not receive any money from them. Arreaza: That's it for today's episode of Rio Bravo qWeek. If you enjoyed this episode, share it with a colleague or medical student who may need to know about BPA. I'm Dr. Arreaza, signing off.Cameron: Hopefully, in the future I will talk to you about more endocrine disrupting chemicals. Thanks for listening._____________________Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Carwile, J. L., & Michels, K. B. (2009). Urinary bisphenol A and obesity: NHANES 2003–2006. Environmental Research, 111(6), 825–830.Carwile, J. L., et al. (2011). Canned soup consumption and urinary bisphenol A: A randomized crossover trial. JAMA, 306(20), 2218–2220.Centers for Disease Control and Prevention (CDC). (2004). Fourth National Report on Human Exposure to Environmental Chemicals.Gao, X., et al. (2020). Urinary bisphenol A and mortality risk. JAMA Network Open, 3(8), e2011620.Lang, I. A., et al. (2008). Association of urinary bisphenol A with medical disorders and laboratory abnormalities in adults. JAMA, 300(11), 1303–1310.Manikkam, M., et al. (2013). Epigenetic transgenerational inheritance of disease. PLOS ONE, 8(1), e55387.Mustieles, V., et al. (2015). Bisphenol A and neurodevelopmental outcomes in children. Environmental Health Perspectives, 123(7), 689–695.Peretz, J., et al. (2014). Bisphenol A and reproductive health. Environmental Health Perspectives, 122(8), 775–786.Rochester, J. R., & Bolden, A. L. (2015). Bisphenol S and F: A systematic review. Environmental Health Perspectives, 123(7), 643–650.Snijder, C. A., et al. (2013). Fetal growth and prenatal exposure to bisphenol A. Environmental Health Perspectives, 121(3), 393–398.World Wildlife Fund (WWF). (2019). No Plastic in Nature: Assessing Plastic Ingestion from Nature to People.University of Newcastle (Australia). (2019). Human Consumption of Microplastics.Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

Die Themen in den Wissensnachrichten +++ Veggie-Hundefutter schneidet in Tests ähnlich ab wie fleischhaltiges +++ Unser Planet hat nur begrenzte Kapazitäten für die CO2-Speicherung +++ Warum zu viel Handy auf dem Klo keine gute Idee ist +++**********Weiterführende Quellen zu dieser Folge:Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK. Plos One, 03.09.2025A prudent planetary limit for geologic carbon storage. Nature, 03.09.2025Smartphone use on the toilet and the risk of hemorrhoids. Plos One, 03.09.2025Is there a relationship between organisational climate and job satisfaction? A view from a systematic review and meta-analysis. World Review of Entrepreneurship, Management and Sustainable Development, 01.09.2025Colorless and unidirectional diffractive-type solar concentrators compatible with existing windows. Photonix, 28.07.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Can a student's body size affect their grades? Research says yes. In this episode of The Scenic Route, Jen explores how fat bias and socioeconomic bias shape grades, opportunities, and self-worth.You'll hear:A personal story of how weight stigma shows up in healthcare.A German study of 14,000 students showed that overweight and lower-income kids receive lower grades than equally capable peers.Why grades often reflect compliance, neatness, and bias more than actual learning.How to judge whether a study is credible using reliability, objectivity, and validity and why validity is the trickiest.Practical steps for parents, teachers, and students to challenge fatbias in schools and beyond.Grades don't just decide report cards. They decide futures. When body size and class bias affect grades, kids are taught that some people matter less.This episode is a call to question those systems and to push for a world where all kids can thrive.

What determines who you vote for?  You probably think it's due to rational reasons. Economy. Sustainability. Immigration. Growth.  But research shows that your choice of vote isn't as logical as you might expect.  In fact, all of our votes can be swayed by a largely irrelevant factor.  And this factor can be used to change what we eat, wear, drink and buy.  Hear how, on today's episode of Nudge with Phil Graves. ---  Phil's book: https://shorturl.at/kzAta Phil's consultancy: https://www.philipgraves.net/consultancy/ Subscribe to the (free) Nudge Newsletter: https://nudge.ck.page/profile  Connect on LinkedIn: https://www.linkedin.com/in/phill-agnew-22213187/  Watch Nudge on YouTube: https://www.youtube.com/@nudgepodcast/ --- Today's sources: Cialdini, R. B., Reno, R. R., & Kallgren, C. A. (1990). A focus theory of normative conduct: Recycling the concept of norms to reduce littering in public places. Journal of Personality and Social Psychology, 58(6), 1015–1026. Davis, C. J., Bowers, J. S., & Memon, A. (2011). Social influence in televised election debates: A potential distortion of democracy. PLoS ONE, 6(3), e18154. Latané, B., & Darley, J. M. (1968). Group inhibition of bystander intervention in emergencies. Journal of Personality and Social Psychology, 10(3), 215–221. Martin, S. J. (2024). Influence at work: Capture attention, connect with others, convince people to act. The Economist Books (Pegasus Books). Tanner, R. J., Ferraro, R., Chartrand, T. L., Bettman, J. R., & Van Bagren, R. (2008). Of chameleons and consumption: The impact of mimicry on choice and preferences. Journal of Consumer Research, April. Trott, D. (2023). Crossover creativity: Real-life stories about where creativity comes from. Harriman House.

Die Themen in den Wissensnachrichten: +++ Junge Erwachsene sind deutlich unglücklicher geworden +++ Durch Klimawandel mehr Superzellen-Gewitter in Europa +++ Hummeln folgen Ernährungsplan +++**********Weiterführende Quellen zu dieser Folge:The declining mental health of the young and the global disappearance of the unhappiness hump shape in age, Plos One 27.08. 2025European supercell thunderstorms—A prevalent current threat and an increasing future hazard. Science Advances, 27.08. 2025Nutrient niche dynamics among wild pollinators, Proceedings of the Royal Society B, 27.08. 2025The evolution of hominin bipedalism in two steps, Nature, 27.08. 2025Declines of ebony and ivory are inextricably linked in an African rainforest, Science Advances 27.08. 2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Your eyes are not cameras—they are clocks. Every cell and organ in your body is orchestrated by the light you let in, making light the most powerful regulator of health. More than ever, I believe the “light diet” is a foundational lifestyle change in the fight against chronic disease. That's why today's guest is one of the most important I've had—a true pioneer in the science of light and health.Dr. Martin Moore-Ede is a world-renowned circadian biology expert with over four decades of research on how light affects sleep, fatigue, and chronic diseases. As a former Harvard Medical School professor, he helped discover the brain's master clock—the suprachiasmatic nucleus—and authored the bestselling The Clocks That Time Us. In 1983, he founded CIRCADIAN®, a global firm optimizing 24/7 workforce performance, and later launched CIRCADIAN Light and CIRCADIAN ZircLight to counter the health risks of artificial lighting.In this episode, we explore:How proper light exposure can increase lifespan by up to five years—and how being “dumb with light” is now correlated with everything from cancer and diabetes to autoimmune and psychiatric disorders.When to wake up, how much outdoor light we need daily, the massive difference in lux between indoor and outdoor light, and the critical role of the brain's internal clock.Why early sunlight matters, and how flawed studies distorted our understanding of sunlight and cataracts.The rise in breast cancer since widespread electrification—now 70x more common.How hospital window placement can influence recovery from depression and anxiety by up to 50%.Why Dr. Moore-Ede gets outside every day—rain, sun, or snow—without sunglasses or eyewear.Whether you're new to circadian science or already light-aware, this episode will shift how you think about health.Contact and Resources: Website – thelightdoctor.com Website – bluesafe24.com Website – circadianlight.orgReferenced Studies Mentioned:Gbyl K et al. (2016). Southeast-facing hospital rooms and faster discharge. Neuropsychobiology.Farahmand B et al. (2009). Golf and reduced mortality. Scand J Med Sci Sports.Boubekri M et al. (2014). Daylight improves health and sleep in office workers. J Clin Sleep Med.Teicher MH et al. (2023). Bright light therapy boosts brain function in adolescents. PLoS One.Support the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/

ReferenceseLife 2020;9:e55828 Int J Mol Sci. 2019 Mar; 20(5): 1223.PLoS One. 2014 Nov 25;9(11):e113939Guerra, DJ.2025. Unpublished Lectures.Oncotarget. 2017 Aug 22; 8(34):55967–55983The Journal of Biological Chemistry2012.287, 40924-40937.Lennon/McCartney, Harrison. 1967. SPLHCB lp. BEATLEShttps://music.youtube.com/playlist?list=OLAK5uy_k0N28ttgCjdEqyy02W7h0v1Kg78hs9AnM&si=OvggJwx7xHkB4vaZGreen, C McVie, J. McVie, Fleetwood, Spencer Welch. 1971 Future Games, lp. Fleetwood Machttps://music.youtube.com/playlist?list=OLAK5uy_myXM7dOObGkQ9rtg96p8QDy_mvV_3Nwt0&si=zZrLBLHHYbgF2-gT Strauss, R. 1896. Also Sprach Zarathustra. OP 30.https://music.youtube.com/playlist?list=OLAK5uy_lcbYBHtM1a-0cclaB_xMKI9e9Efma3OkQ&si=FQm7nzrxNPZKNZiu

Stress isn't just “in your head”—it changes your biology. It depletes nutrients like magnesium, vitamin C, B vitamins, and zinc, and keeps your body in survival mode. Supplements can help, but they won't heal you if the root cause—stress—remains. In this episode, I talk about why stress management is as critical as nutrition, how CBT and EMDR support your healing, and why lab testing matters before wasting money on supplements.   References from this episode: Juster R-P, McEwen BS, Lupien SJ. (2020). Allostatic load and allostatic overload: Clinical implications. Frontiers in Behavioral Neuroscience. https://doi.org/10.3389/fnbeh.2020.00046  Singewald N, et al. (2004). Magnesium-deficient diet alters anxiety-related behavior in mice. Journal of the American College of Nutrition. https://doi.org/10.1080/07315724.2004.10719406  Harrison FE, May JM. (2009). Vitamin C function in the brain: New evidence links ascorbate to neurotransmitter function. Brain Research Bulletin. https://doi.org/10.1016/j.brainresbull.2009.05.018  de Oliveira IJL, et al. (2015). Effects of oral vitamin C supplementation on anxiety in students. Nutrition Journal. https://doi.org/10.1186/1475-2891-14-36  Stough C, et al. (2011). The effects of 90-day administration of a high-dose B-complex vitamin on work stress. Human Psychopharmacology. https://doi.org/10.1002/hup.1190  Singh A, et al. (1991). Effect of acute stress on plasma zinc. Biological Trace Element Research. https://doi.org/10.1007/BF02990385  Hofmann SG, Asnaani A, Vonk IJJ, Sawyer AT, Fang A. (2018). The efficacy of cognitive behavioral therapy: A review of meta-analyses. Frontiers in Psychology. https://doi.org/10.3389/fpsyg.2012.00117  Shaw RJ, et al. (2019). Mindfulness-based stress reduction and CBT for HPA axis habituation. Psychoneuroendocrinology. https://doi.org/10.1016/j.psyneuen.2019.104420  Chen Y-R, Hung K-W, Tsai J-C, et al. (2014). Efficacy of EMDR for PTSD: A meta-analysis. PLoS ONE. https://doi.org/10.1371/journal.pone.0103676   Explore more support: Better Than Before Breast Cancer Life Coaching Membership: https://www.thebreastcancerrecoverycoach.com/lifecoaching  Creating a Life You Love in 168 Hours a Week: https://www.thebreastcancerrecoverycoach.com/168-hours-sp    Let's Connect! If this episode helped you breathe a little easier, please share it with a friend or leave a review. Every share helps spread this message of hope, healing, and whole-person wellness.

In this episode of SpaceTime, we delve into intriguing new research that challenges our understanding of Earth's climatic history, the discovery of a rare astronomical phenomenon, and China's advancements in lunar exploration.Did a Comet Trigger the Younger Dryas Cool Off?A groundbreaking study has emerged suggesting that a massive comet may have instigated Earth's Younger Dryas cool off event, traditionally attributed to glacial meltwater. Analysis of ocean sediments published in the journal PLOS One reveals geochemical clues that support the hypothesis of Earth encountering a disintegrating comet around 12,800 years ago. This event could have led to rapid cooling, with temperatures plummeting by approximately 10 degrees Celsius within a year. The findings indicate a potential link between comet dust and significant climate shifts, inviting further investigation into this captivating theory.Discovery of a Rare White Dwarf Merger RemnantAstronomers have identified an ultra-massive white dwarf star resulting from the merger of two stars, rather than the evolution of a single star. This discovery, made possible by NASA's Hubble Space Telescope, suggests that such white dwarf mergers may be more common than previously thought. The object, catalogued as WD0525 526, is located 126 light years away and is about 20% more massive than our Sun. Hubble's ultraviolet observations revealed carbon in its atmosphere, a sign of its violent origin, challenging previous assumptions about white dwarf formation.China Tests Its New Manned Lunar LanderIn a significant milestone for lunar exploration, China has successfully conducted a test flight of its new manned lunar landing craft, named Lanyu. This test, which included a controlled landing and takeoff, marks a crucial step in China's ambitions to send taikonauts to the Moon by 2030. The Lanyu is designed to carry astronauts from lunar orbit to the surface and back, with plans for a permanent lunar base in collaboration with Russia in the early 2030s.www.spacetimewithstuartgary.com✍️ Episode ReferencesPLOS Onehttps://journals.plos.org/plosone/Nature Astronomyhttps://www.nature.com/natureastronomy/NASA Hubble Space Telescopehttps://www.nasa.gov/mission_pages/hubble/main/index.htmlBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-space-astronomy--2458531/support.

Let me know what you loved about the episode!Do you ever feel like your mind is constantly cluttered with notifications, endless scrolling, and the pressure to always be ‘on'? In this episode, I share how taking a mindful digital detox can help you (and me!) reclaim your focus, reduce stress, and improve your mental clarity.We dive into why screens are so addictive, the impact of digital distractions on your brain and creativity, and how constant device use can even disrupt your sleep by affecting melatonin production. I also guide you through a gentle visualisation to help you reconnect with the present moment, boost creativity, and feel calmer in your daily life.By the end of this episode, you'll have practical tips to start your own digital detox, improve your well-being, and create space for focus, creativity, and presence in your life.What you'll get from this episode:Why taking breaks from screens is essential for mental clarity and focus.How excessive screen time affects your brain, memory, and decision-making (Loh & Kanai, 2014, PLoS ONE).The science behind screen addiction and why notifications trigger dopamine hits.How blue light impacts melatonin production and your sleep quality.Ways a digital detox can boost creativity, reduce stress, and enhance overall well-being.Practical tips to set boundaries with technology and create unplugged time.A guided visualisation to reconnect with the present moment and calm your mind.Try This Today:I challenge you to join me in a 24-hour digital detox. Come on over to my Facebook group and let me know how you feel about this!✨ Doors are now open for Magnetic Manifestation, my 6-week live experience to help you clear subconscious blocks, align your energy, and become magnetic to your desires.We start mid-September, with lifetime access to this round's replays included. Find all the details and join us here https://magneticmanifestation.lisadavidge.co.uk/magneticmanifestationSupport the showLinks + Resources:

Die Themen in den Wissensnachrichten: +++ Unterschiedliche Musik weckt unterschiedliche Erinnerungen +++ Gene beeinflussen Gewicht auch ohne Vererbung +++ Auch KI versteht Dialekte schlecht +++**********Weiterführende Quellen zu dieser Folge:Qualities of music-evoked autobiographical memories are associated with auditory features of the memory-evoking music/ Plos One, 20.08.2025The association between parental BMI and offspring adiposity: A genetically informed analysis of trios/ Plos Genetics, 05.08.2025A Multi-Dialectal Dataset for German Dialect ASR and Dialect-to-Standard Speech Translation/ Interspeech, 17. bis 21.08.2025Scalable metasurface-enhanced supercool cement/ Science Advances, 20.08.2025VIVIT: Resolving trans-scale volumetric biological architectures via ionic glassy tissue/ Cell, 11.08.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

This week on The Marathon Running Podcast, we tackle the most misunderstood phase of marathon training: the taper. Host [Insert Host Name Here] compares this final stage to the difference between cramming and consolidating for a major exam, sharing a personal story about how his own failed taper taught him the hard way that less is truly more. For solo runners like Letty, mastering the taper is especially crucial, as it's the final step to ensure your body is primed for an independent race. We dive into the science of supercompensation, explaining how resting unlocks your full physiological potential by rebuilding muscle, replenishing glycogen, and boosting your immune system.Whether you're battling the "taper crazies" or feeling anxious about the reduced mileage, this episode is a deep dive into the practical blueprint and mental strategies you need to arrive at the starting line feeling strong, confident, and ready for your best race. Trust the process, because the taper isn't about losing fitness—it's about unlocking it for that final, glorious solo effort.Here are our research citations:

Development and Validation of the Behavioral Tendencies QuestionnaireIn this episode, Dr. Jud Brewer and Dr. Nicholas Van Dam discuss the creation of the Behavioral Tendencies Questionnaire (BTQ), a novel tool for assessing personality traits based on behavioral approach, avoidance, and equivocation. Rooted in both contemporary psychology and ancient Buddhist typologies, the BTQ categorizes individuals into three primary temperaments: Greedy/Faithful (approach-oriented), Aversive/Discerning (avoidance-oriented), and Deluded/Speculative (equivocation-oriented). This study validated the BTQ using modern psychometric techniques, demonstrating its utility for personality research and mindfulness-based interventions. Tune in to learn how these behavioral tendencies shape our interactions, decision-making, and well-being.Full Reference:Van Dam, N. T., Brown, A., Mole, T. B., Davis, J. H., Britton, W. B., & Brewer, J. A. (2015). Development and Validation of the Behavioral Tendencies Questionnaire. PLoS ONE, 10(11), e0140867. https://doi.org/10.1371/journal.pone.0140867Let's connect on Instagram

Het is 40.000 jaar geleden. De jonge Doi staat oog in oog met zijn verre familie, een groep dansende neanderthalers. Zullen ze hem accepteren? Wilde Eeuwen, het begin. Iedere vrijdag een nieuwe aflevering. Meer informatie: nrc.nl/wilde-eeuwenHeeft u vragen, suggesties of ideeën over onze journalistiek? Mail dan naar onze ombudsman via ombudsman@nrc.nl.Tekst en presentatie: Hendrik SpieringRedactie en regie: Mirjam van ZuidamMuziek, montage en mixage: Rufus van BaardwijkBeeld: Jeen BertingVormgeving: Yannick MortierVoor deze aflevering is onder meer gebruikt gemaakt van deze literatuur: Francesca Romagnoli e.a. (eds) 'Updating Neanderthals. Understanding Behavioural Complexity in the Late Middle Palaeolithic', Academic Press 2022 Mateja Hajdinjak e.a ‘Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry' in Nature 8 april 2021. Rebecca Wragg Sykes. 'Kindred. Neanderthal Life, Love, Death and Art', Bloomsbury 2021 Rudolf Botha. 'Neanderthal Language. Demystifying the Linguistic Powers of our Extinct Cousins', Cambridge University Press 2020 Katerina Harvati. 'Paleoanthropology of the Balkans and Anatolia. Human Evolution and its Context', Springer Press 2016 Qiaomei Fu e.a. ‘An early modern human from Romania with a recent Neanderthal ancestor' in Nature, 13 augustus 2015. Wil Roebroeks en Paola Villa ‘Neandertal Demise: An Archaeological Analysis of the Modern Human Superiority Complex' in PLOS One, 30 april 2014. João Zilhão e.a. ‘The Peştera cu Oase People. Europe's Earliest Modern Humans' in K. Boyle e.d. (eds) Rethinking the Human Revolution, McDonald Institute for Archaeological Research, 2007.Zie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

CN: In einer Meldung werden die Themen Selbstverletzung und Suizid behandelt.**********Die Themen in den Wissensnachrichten: +++ ChatGPT liefert Tipps zu Drogennehmen, Selbstverletzung und mehr +++ Viele Kakadu-Arten haben Tanzmoves drauf +++ Wie Kakao-Plantagen klimafreundlicher werden können +++**********Weiterführende Quellen zu dieser Folge:Fake Friend. How ChatGPT betrays vulnerable teens by encouraging dangerous behavior, Center for Countering Digital Hate, 06.08.2025Dance behaviour in cockatoos: Implications for cognitive processes and welfare, Plos One, 06.08.2025Beyond victimhood and perpetration: Reconstruction of the ingroup's historical role in eight Eastern and Western European countries under Nazi occupation, Political Psychology, 25.09.2024The unrealized potential of agroforestry for an emissions-intensive agricultural commodity, Nature Sustainability, 06.08.2025Fatigue in long-term cancer survivors: prevalence, associated factors, and mortality. A prospective population-based study. British Journal of Cancer, 15.07.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Nutrition science plays a pivotal role in shaping public health advice, but the influence of industry funding on research has become a pressing concern. In this episode we want to examine whether we can trust nutrition studies funded by food and beverage companies, and how you can discern study credibility.  The discussion is highly relevant in today's landscape, where conflicts of interest and bias in research are under scrutiny amidst debates on sugar, processed foods, and diet recommendations. By exploring how industry sponsorship might skew results or interpretations, this episode speaks to broader issues of scientific trustworthiness and evidence-based policy in nutrition and public health.  In this episode, we take a look at some recent publications that showed how study results and reporting differed significantly depending on if industry had funded the study or not. We delve into how this happens. As most often it is not a case of data fabrication or corruption, but rather how bias leads to studies being designed and reported differently. We walk through some examples, as well as highlighting some industry-funded studies that didn't provide a “pro-industry” result and conclusion. The hope is that the episode allows you to understand why this is a problem, how to spot it, and how to know if you can trust the results of an industry-funded study. Timestamps [00:36] Alan's upcoming study [04:47] Discussion on industry funding in nutrition research [15:06] Case study: industry influence on red meat research [30:43] Case study: artificial sweeteners and industry influence [36:37] Case study: sugar industry's role in research [38:06] Critical appraisal of industry-funded studies [51:58] Case study: when industry-funded study results can be trusted [01:01:51] Guidelines for assessing research quality [01:07:14] Key ideas segment (premium-only) Related Resources Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Join Alan's Alinea Nutrition Research Hub Enroll in the next cohort of our Applied Nutrition Literacy course Recommended episode: #472: Compared To What? – Understanding Food Substitution Analysis & Adjustment Models Studies mentioned: López-Moreno et al., Am J Clin Nutr. 2025 Jun;121(6):1246-1257 Tobias, 2025 – You are what you don't eat Mandrioli D, Kearns CE, Bero LA (2016) PLOS ONE 15(3): e0230469 Schillinger et al., Ann Intern Med. 2016 Nov 1;165(12):895–897 Schmidt et al., 2021 – The impact of diets rich in low-fat or full-fat dairy on glucose tolerance and its determinants: a randomized controlled trial Schmidt et al., 2021 – Impact of low-fat and full-fat dairy foods on fasting lipid profile and blood pressure: exploratory endpoints of a randomized controlled trial

RETRACTED // In this episode of The Studies Show, Tom and Stuart discuss retraction, the process of removing articles from the scientific record. How often is it due to fraud? How many papers get retracted—and is the number increasing? Is it good or bad for a scientist to retract an article? // RETRACTEDWant even more podcasts? Now our sponsor, Works in Progress magazine, has a podcast where their editors talk to people with interesting progress-related ideas. One such person is the historian Anton Howes, who is interviewed about the unexpected origins of the Industrial Revolution in the latest episode. Find it at worksinprogress.news.Show notes* Retraction Watch, the extremely useful website that tracks and investigates retractions* Science's writeup of the long process of retracting the GFAJ-1 “arsenic bacteria” paper* Original paper; retraction note; response from the authors* The first known retraction, from 1755* Retraction Watch's discussion of it* Adam Marcus and Ivan Oransky on tracking retractions over time* 2022 PLOS ONE article on the number of retractions over time* Scholarly Kitchen post on the rate of retractions over time* Nature article on the 10,000 retractions in 2023 alone* 2011 article on the causes of retractions* 2012 article on the same: misconduct is found to account for the biggest proportion* James Heathers on the disastrous story of Wiley buying Hindawi* The retraction guidelines from COPE* The paper with a diagram of a very well-endowed rat* Are authors punished for retractions? Not necessarily* Reputational advantage from correcting errors* 2022 article on how scientists still regularly cite retracted papers (without knowing they're retracted)CreditsWe're very grateful to Ivan Oransky from Retraction Watch for his help with this episode. Any mistakes are ours. The Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe

In this episode Dr Sarah Howard discusses healthy ageing in dogs with Dr Matthew Muir. Topics discussed include: The reason ageing is currently a hot topic. What leads to an increased lifespan and better quality of life? Diet changes that can impact ageing in dogs. Dr Muir discusses what we should avoid in order to increase lifespan. Matthew goes into details of what dogs' diets should look like to prevent disease. How often should we be feeding our pets? What happens to the gut microbiome as dogs get older? Dr Muir delves into supplements that can be beneficial for ageing and emerging tools that are becoming available. The importance of preventative medicine - proactive vs reactive care. Accelerators of biological ageing. Additional resources: https://pubmed.ncbi.nlm.nih.gov/11991408/ https://pmc.ncbi.nlm.nih.gov/articles/PMC11675035/https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1355560/full https://pmc.ncbi.nlm.nih.gov/articles/PMC11505706/ https://www.mdpi.com/1660-3397/18/11/564https://pmc.ncbi.nlm.nih.gov/articles/PMC4936929/ https://pubmed.ncbi.nlm.nih.gov/22216092/ Adams VJ, Watson P, Carmichael S, Gerry S, Penell J, Morgan DM. Exceptional longevity and potential determinants of successful ageing in a cohort of 39 Labrador retrievers: results of a prospective longitudinal study. Acta Vet Scand. 2016;58:29. doi:10.1186/s13028-016-0204-8 Cupp CJ, Jean-Philippe C, Kerr WW, Patil AR. Effect of nutritional interventions on longevity of senior cats. Int J Appl Res Vet Med. 2007;5(3):133–149 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Jackson J, Radford AD, Belshaw Z, Wallis LJ, Kubinyi E, German AJ, Westgarth C. Using veterinary health records at scale to investigate ageing dogs and their common issues in primary care. J Small Anim Pract. 2025;66(2):81–91. doi:10.1111/jsap.13809 Creevy KE, O'Neill DG, Promislow DEL. Morbidity and mortality in elderly dogs – a model for human aging. BMC Vet Res. 2022;18(1):456. doi:10.1186/s12917-022-03518-8 Lewis TW, Wiles BM, Llewellyn-Zaidi AM, Evans KM, O’Neill DG. Longevity and mortality in Kennel Club registered dog breeds in the UK in 2014. Canine Genet Epidemiol. 2018;5:10. doi:10.1186/s40575-018-0066-8 Kealy RD, Lawler DF, Ballam JM, Mantz SL, Biery DN, Greeley EH, Lust G, Segre M, Smith GK, Stowe HD. Effects of diet restriction on life span and age-related changes in dogs. J Am Vet Med Assoc. 2002;220(9):1315–1320. doi:10.2460/javma.2002.220.1315 Guelfi G, Capaccia C, Tedeschi M, Bufalari A, Leonardi L, Cenci-Goga B, Maranesi M. Dog aging: a comprehensive review of molecular, cellular, and physiological processes. Cells. 2024;13(24):2101. doi:10.3390/cells13242101 Laflamme DP. Nutritional care for aging cats and dogs. Vet Clin North Am Small Anim Pract. 2012;42(4):769–791. doi:10.1016/j.cvsm.2012.04.002 Hall JA, Jewell DE. Feeding healthy beagles medium-chain triglycerides, fish oil, and L-carnitine offsets age-related changes in serum fatty acids and carnitine metabolites. PLoS One. 2012;7(11):e49510. doi:10.1371/journal.pone.0049510 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Bray EE, Zheng Z, Tolbert MK, McCoy BM, Kaeberlein M, Kerr KF; Dog Aging Project Consortium. Once-daily feeding is associated with better health in companion dogs: results from the Dog Aging Project. GeroScience. 2022;44(3):1779–1790. doi:10.1007/s11357-022-00575-7 Palaseweenun P, Hagen‐Plantinga EA, Schonewille JT, Koop G, Butre C, Jonathan M, Wierenga PA, Hendriks WH. Urinary excretion of advanced glycation end products in dogs and cats. J Anim Physiol Anim Nutr (Berl). 2021;105(1):149–156. doi:10.1111/jpn.13347 Yang L, Yang L, Cai Y, Luo Y, Wang H, Wang L, Chen J, Liu X, Wu Y, Qin Y, Wu Z, Liu N. Natural mycotoxin contamination in dog food: a review on toxicity and detoxification methods. Ecotoxicol Environ Saf. 2023;257:114948. doi:10.1016/j.ecoenv.2023.114948 Bridglalsingh S, Archer-Hartmann S, Azadi P, Barbier de La Serre C, Remillard RL, Sunvold GD, Bartges JW. Association of four differently processed diets with plasma and urine advanced glycation end products and serum soluble receptor for advanced glycation end products concentration in healthy dogs. J Anim Physiol Anim Nutr (Berl). 2024;108(3):735–751. doi:10.1111/jpn.13927 Marchi PH, Vendramini THA, Perini MP, Zafalon RVA, Amaral AR, Ochamotto VA, Da Silveira JC, Dagli MLZ, Brunetto MA. Obesity, inflammation, and cancer in dogs: review and perspectives. Front Vet Sci. 2022;9:1004122. doi:10.3389/fvets.2022.1004122 Schmid SM, Hoffman JM, Prescott J, Ernst H, Promislow DEL, Creevy KE; Dog Aging Project Consortium. The companion dog as a model for inflammaging: a cross-sectional pilot study. GeroScience. 2024;46(6):5395–5407. doi:10.1007/s11357-024-01217-w Ren J, Li H, Zeng G, Pang B, Wang Q, Wei J. Gut microbiome-mediated mechanisms in aging-related diseases: are probiotics ready for prime time? Front Pharmacol. 2023;14:1178596. doi:10.3389/fphar.2023.1178596 Parker A, Romano S, Ansorge R, Aboelnour A, Le Gall G, Savva GM, Pontifex MG, Telatin A, Baker D, Jones E, Vauzour D, Rudder S, Blackshaw LA, Jeffery G, Carding SR. Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain. Microbiome. 2022;10:68. doi:10.1186/s40168-022-01262-3 Ulluwishewa D, Anderson RC, McNabb WC, et al. Regulation of tight junction permeability by intestinal bacteria and dietary components. J Nutr. 2011;141(5):769–76. doi:10.3945/jn.110.135657 Cao L, Lee SG, Lim KT, Kim HR. Potential anti-aging substances derived from seaweeds. Mar Drugs. 2020;18(11):564. doi:10.3390/md18110564 Grzeczka A, Graczyk S, Kordowitzki P. Pleiotropic effects of resveratrol on aging-related cardiovascular diseases—what can we learn from research in dogs? Cells. 2024;13(20):1732. doi:10.3390/cells13201732 Kusaba A, Arai T. Shiitake mushroom powder supplementation increases antioxidative activity in dogs. Front Vet Sci. 2024;11:1355560. doi:10.3389/fvets.2024.1355560 Cho HW, Choi S, Seo K, Kim KH, Jeon JH, Kim CH, Lim S, Jeong S, Chun JL. Gut microbiota profiling in aged dogs after feeding pet food contained Hericium erinaceus. J Anim Sci Technol. 2022 Sep;64(5):937-949. Kaur J, Seshadri S, Golla KH, Sampara P. Efficacy and safety of standardized ashwagandha (Withania somnifera) root extract on reducing stress and anxiety in domestic dogs: A randomized controlled trial. J Vet Behav. 2022;51:8–15. Bharani KK, Devarasetti AK, Carey L, Khurana A, Kollipaka R, Hanuman DDV, Chetla VS, Banothu AK. Effects of ashwagandha (Withania somnifera) root extract on aging-related changes in healthy geriatric dogs: A randomized, double-blinded placebo-controlled study. Vet Med Sci. 2024 Sep;10(5):e1556 Sacoor C, Marugg JD, Lima NR, Empadinhas N, Montezinho L. Gut-brain axis impact on canine anxiety disorders: new challenges for behavioral veterinary medicine. Vet Med Int. 2024;2024:2856759. doi:10.1155/2024/2856759 Lee E, Carreras-Gallo N, Lopez L, Turner L, Lin A, Mendez TL, Went H, Tomusiak A, Verdin E, Corley M, Ndhlovu L, Smith R, Dwaraka VB. Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions. Aging (Albany NY). 2024;16(4):3088–3106. doi:10.18632/aging.205581 Bitto A, Ito TK, Pineda VV, LeTexier NJ, Huang HZ, Sutlief E, Tung H, Vizzini N, Chen B, Smith K, Meza D, Yajima M, Beyer RP, Kerr KF, Davis DJ, Gillespie CH, Snyder JM, Treuting PM, Kaeberlein M. Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice. eLife. 2016;5:e16351. doi:10.7554/eLife.16351 Urfer SR, Kaeberlein TL, Mailheau S, Bergman PJ, Creevy KE, Promislow DEL, Kaeberlein M. A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs. GeroScience. 2017;39(2):117–127. doi:10.1007/s11357-017-9972-z Kaeberlein M, Creevy KE, Promislow DEL. The Dog Aging Project: translational geroscience in companion animals. Mamm Genome. 2016;27(7–8):279–288. doi:10.1007/s00335-016-9638- Mulder IE, Schmidt B, Lewis M, Delday M, Stokes CR, Bailey M, Aminov RI, Gill BP, Pluske JR, Mayer CD, Kelly D. Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity. PLoS One. 2011;6(12):e28279. doi:10.1371/journal.pone.0028279 Hemida M, Vuori KA, Moore R, Anturaniemi J, Hielm-Björkman A. Early life modifiable exposures and their association with owner-reported inflammatory bowel disease symptoms in adult dogs. Front Vet Sci. 2021;8:552350. doi:10.3389/fvets.2021.552350 McMahon JE, Graves JL, Tovar AP, Peloquin M, Greenwood K, Chen FL, Nelson M, McCandless EE, Halioua-Haubold CL, Juarez-Salinas D. Translational immune and metabolic markers of aging in dogs. Sci Rep. 2025;15:14460. doi:10.1038/s41598-025-51976-3 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Santos JDP, Cunha E, Nunes T, Tavares L, Oliveira M. Relation between periodontal disease and systemic diseases in dogs. Res Vet Sci. 2019;125:136–140. doi:10.1016/j.rvsc.2019.05.011 Selting KA, Ringold R, Husbands B, Pithua PO. Thymidine kinase type 1 and C-reactive protein concentrations in dogs with spontaneously occurring cancer. J Vet Intern Med. 2016;30(4):1159–1166. doi:10.1111/jvim.13954 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Clark JD, Rager DR, Crowell-Davis S, Evans DL. Housing and exercise of dogs: effects on behaviour, immune function and cortisol concentration. Lab Anim Sci. 1997;47(5):500–510 See omnystudio.com/listener for privacy information.

TDC 059: Live Wild or Die Boring: The Urgent Case for Reconnecting with the Natural World (Part 1)Why nature isn't just good for your soul—it's essential for survival, creativity, and breakthrough innovation.Episode SummaryIn this episode of The Digital Contrarian, host Ryan Levesque shares insights from recording his upcoming book Return to Real and reveals shocking research about our digital lifestyle.You'll discover how concrete environments increase early death by 12%, learn why nature walks boost creativity by 60%, and understand why tech founders won't use their own products.Question of the Day

Today's episode features guest host Michael Upshall (guest editor, Charleston Briefings) who talks with Damien Pattinson, Executive Director, eLife Sciences Publications, Ltd. Damien earned his PhD in neuroscience. After a postdoc at Kings College, London, UK, he began his career in scholarly publishing almost twenty years ago, first joining BMJ as a scientific editor, then PLOS ONE as executive director and then as editorial director, and Research Square as VP of Publishing Innovation.  Damien joined eLife in 2020. In this conversation, he talks about Open Science and the eLife publishing model.  LinkedIn: https://www.linkedin.com/in/mupshall/ https://www.linkedin.com/in/damian-pattinson-b054508/ Twitter: Keywords:  #eLife #OpenScience #OpenResearch #Research #FutureOfResearch #ResearchIntegrity #AcademicResearch #OpenAccess #OpenSource #PeerReview #HigherEducation #LibraryInnovation #Innovation #LibraryJobs #career #collaboration #scholcomm #ScholarlyCommunication #libraries #librarianship #LibraryNeeds #LibraryLove #ScholarlyPublishing #AcademicPublishing #publishing #LibrariesAndPublishers #podcasts

Pay attention. Focus on your breathing. Live in the moment. Accept yourself. Do you have a self? Focus on that self. And so on. This is, of course, the practice of mindfulness meditation, which seems to be everywhere: in schools, at work, in apps, and all over the scientific literature.Do any of the claimed effects of mindfulness meditation (relieving your depression! Changing the structure of your brain!) actually add up? In this episode of The Studies Show, Tom and Stuart focus calmly, serenely, and gratefully on their own thoughts, and then find out.The Studies Show is brought to you by Works in Progress magazine. WiP has started doing its own podcasts! Don't worry—we give you permission to listen to them. The one we mentioned on the show this week is an interview with Stian Westlake, the extremely interesting Chief Executive of the UK's Economic and Social Research Council and expert in the “intangible” economy.Show notes* When Sam Harris tried to get Richard Dawkins to meditate on a podcast* Tom's 2014 article on mindfulness, before all the criticisms started appearing* Mindfulness tips from the NHS* The 2017 critical paper from Perspectives on Psychological Science* 2014 meta-analysis finding no effect beyond active controls* 2021 meta-analysis drawing a similar conclusion* The now-retracted 2023 Scientific Reports meta-analysis on mindfulness and brain structure* Eiko Fried's article discussing his experience critiquing the paper* The eventual retraction note* PLOS ONE paper from 2016 on the number of positive results found in mindfulness trials* 2015 meta-analysis on mindfulness in healthcare* The eventual retraction note* 2022 writeup of the MYRIAD study of school-based mindfulness techniques* Critical opinion piece by a mindfulness sceptic* Study on mindfulness in the context of neoliberal capitalismCreditsThe Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe

Are cancer rates going up or down? It seems like depending on where you look, you'll find different answers to the question. What's going on here — have some writers just got it completely wrong? Is it something to do with different types of cancer? Are we being confused by some kind of weird statistical artefact? All of the above? In this episode of The Studies Show, we do our very best to find out.The Studies Show is brought to you by Works in Progress magazine, the ultimate place online to read about new and underrated scientific and technological ideas that could make the world a better place. You can find a huge range of essays online, for free, at www.worksinprogress.co.Show notes* BBC Future article on early-onset cancer rates* BMJ Oncology article on global cancer incidence increasing by 79%* And its online supplementary information* July 2025 Economist article on how the world is winning the war on cancer* Saloni Dattani's 2025 article on the decline in global cancer rates* The GLOBOCAN data update from the IARC, 2002 and 2008* Our World in Data's graph on global cancer incidence over time* Their graph on smoking rates and lung cancer deaths* Their graph on stomach cancer death rates* New RCT on vaping and smoking cessation* A 90% drop in cervical cancer rates in England* The hepatitis B vaccine and a massive drop in liver cancer incidence in China* On H. pylorii, ulcers, and cancer* 2000 JAMA article questioning the utility of the 5-year survival rate statistic* 2014 PLOS ONE article that's more positive about the statistic* Tom's BuzzFeed News article on oncology* RCT of herceptin on breast cancer survival* Study on rates of colorectal cancer * And the same, in relation to BMICreditsThe Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe

Ai microfoni Kuna e Ilaria per la puntata 572. Apre le danze Kuna che, approfittando delle recenti polemiche sull'esame di stato, discute il concetto di scuola senza voto e le sperimentazioni intraprese in Italia e all'estero, da cui emerge come l'idea di limitare l'uso del giudizio numerico alla valutazione finale, se accompagnata da una didattica adeguata, possa migliorare il clima e i risultati dell'apprendimento. Per approfondire:Cristiano Corsini, La fabbrica dei voti. Sull'utilità e il danno della valutazione a scuola, Editori Laterza (2025)Vincenzo Arte, Crescere senza voti, Mondadori, 2023Per la rubrica Scientifibook, Andrea e Giuliana propongono:L'EVOLUZIONISTA RILUTTANTEDavid Quammen – Raffaello Cortina Editore (272 pp, 22 euro)TEMPO DI RITORNOFerdinando Cotugno – Guanda (264 pp, 18 euro)STORIE STRAORDINARIE DI OGGETTI ORDINARIEmily Prokop – Apogeo (215 pp, 22 euro)SONO PARTE DELL'INFINITOKieran Fox – Egea editore (308 p, 26,90 euro)ENRICO FERMI. IL GENIO ATOMICOAndrea Pau – Gallucci (256 pp, 14,90 euro)Dopo una barza PESANTE, Ilaria ci parla di due studi affascinanti che mostrano quanto sia stretta la connessione tra il nostro corpo e la salute. Il primo ci porta nelle profondità del microbiota intestinale, dove i ricercatori hanno identificato un composto chiamato imidazolo propionato (ImP) che potrebbe funzionare sia come campanello d'allarme precoce, sia come causa diretta dell'aterosclerosi. Un piccolo metabolita con un grande impatto sul cuore!Mastrangelo, A., Robles-Vera, I., Mañanes, D. et al., Imidazole propionate is a driver and therapeutic target in atherosclerosis, Nature(2025), https://doi.org/10.1038/s41586-025-09263-wIl secondo studio, invece, ci riporta a terra – letteralmente – perché dimostra che basta camminare un po' più velocemente del solito, circa 14 passi in più al minuto, per migliorare significativamente la funzione fisica, soprattutto nelle persone anziane o a rischio di fragilità. Una buona notizia per chi cerca salute… a piccoli passi!Rubin, D.S., Hung, A., Yamamoto, E., Hedeker, D., Conroy, D.E., Huisingh-Scheetz, M., et al., Walking cadence as a measure of activity intensity and impact on functional capacity for prefrail and frail older adults, PLoS One 20(7): e0323759 (2025), https://doi.org/10.1371/journal.pone.0323759Diventa un supporter di questo podcast: https://www.spreaker.com/podcast/scientificast-la-scienza-come-non-l-hai-mai-sentita--1762253/support.

In this episode of Iron Culture, Dr. Eric Trexler and Dr. Lauren Colenso-Semple discuss science related to attractiveness, coolness, and personality type. They explore scientific studies on the factors associated with perceived attractiveness and "coolness," discussing body fat percentages and societal perceptions. The conversation shifts to how personality traits appear to predict workout preferences and engagement in fitness, then they debate the importance of matching exercise to individual characteristics. Time stamps: 00:00 Introduction to Iron Culture and Guests 5:57 The Science of (Male) Attractiveness 10:39 Evolutionary Underpinnings of Male Attractiveness 13:53 Distorted Perceptions of Attractiveness (In the Fitness World) 20:10 The Irony of Pursuing Attractiveness 22:22 Body-Fat and Optimized Health 24:18 Surprising Article Feedback 28:50 Unrealistic Body Standards and Gender Perceptions 32:49 Achieving the Outcome Versus Doing Hard Things 35:07 Attractiveness is More Than Body Shape/Size 37:48 The Science of Being Cool 47:19 Matching Exercise To Personality Types References: Xia F, Sauciuvenaite J, Bissland R, Hambly C, Starr-Vaanholt L, Faries MD, et al. The relationship between body fatness and physical attractiveness in males. Personality and Individual Differences. 2025 Sep 1;243:113240. de Jager S, Coetzee N, Coetzee V. Facial Adiposity, Attractiveness, and Health: A Review. Front Psychol. 2018 Dec 21;9:2562. Brierley ME, Brooks KR, Mond J, Stevenson RJ, Stephen ID. The Body and the Beautiful: Health, Attractiveness and Body Composition in Men's and Women's Bodies. PLoS One. 2016;11(6):e0156722. Sorokowski P, Kościński K, Sorokowska A, Huanca T. Preference for Women's Body Mass and Waist-to-Hip Ratio in Tsimane' Men of the Bolivian Amazon: Biological and Cultural Determinants. PLoS One. 2014 Aug 22;9(8):e105468. Tovée MJ, Cornelissen PL. Female and male perceptions of female physical attractiveness in front-view and profile. Br J Psychol. 2001 May;92(Pt 2):391–402. Jayedi A, Khan TA, Aune D, Emadi A, Shab-Bidar S. Body fat and risk of all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies. Int J Obes (Lond). 2022 Sep;46(9):1573–81. Hu J, Chen X, Yang J, Giovannucci E, Lee DH, Luo W, et al. Association between fat mass and mortality: analysis of Mendelian randomization and lifestyle modification. Metabolism. 2022 Nov;136:155307. Ramlau-Hansen CH, Thulstrup AM, Nohr EA, Bonde JP, Sørensen TIA, Olsen J. Subfecundity in overweight and obese couples. Hum Reprod. 2007 Jun;22(6):1634–7. Wei S, Schmidt MD, Dwyer T, Norman RJ, Venn AJ. Obesity and menstrual irregularity: associations with SHBG, testosterone, and insulin. Obesity (Silver Spring). 2009 May;17(5):1070–6. Liu Y, Hu X, Xiong M, Li J, Jiang X, Wan Y, et al. Association of BMI with erectile dysfunction: A cross-sectional study of men from an andrology clinic. Front Endocrinol (Lausanne). 2023;14:1135024. https://psycnet.apa.org/doiLanding?doi=10.1037%2Fxge0001799 https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2025.1587472/full

Was wäre wenn …? Hätte ich doch nur … Müsste ich nicht eigentlich…? Das kennt wahrscheinlich jeder von uns: Gedanken, die immer wieder um dieselben Themen kreisen. Man kommt nicht runter vom Gedankenkarussell. Wiederkehrende, belastende Gedanken sind ein zentrales Merkmal vieler psychischer Belastungen. In dieser Folge fragen sich Atze und Leon, warum wir dazu neigen, in solchen Denkschleifen zu verharren und werfen einen Blick auf aktuelle Forschungsansätze und evidenzbasierte Strategien zum Grübeln. Was ist normal und was ist schon nicht mehr gesund? Und was können wir konkret im Alltag tun, um das Gedankenkarussell zu stoppen? Fühlt euch gut betreut Leon & Atze Instagram: https://www.instagram.com/leonwindscheid/ https://www.instagram.com/atzeschroeder_offiziell/ Mehr zu unseren Werbepartnern findet ihr hier: https://linktr.ee/betreutesfuehlen Tickets: Atze: https://www.atzeschroeder.de/#termine Leon: https://leonwindscheid.de/tour/ VVK Münster 2025: https://betreutes-fuehlen.ticket.io/ Quellen: Review zu RNT & Transdiagnostik: Moulds, M. L., & McEvoy, P. M. (2025). Repetitive negative thinking as a transdiagnostic cognitive process. Nature Reviews Psychology, 1-15. https://www.nature.com/articles/s44159-024-00399-6 Übersichtsartikel über die Forschung von Susan Nolen-Hoeksema: Lyubomirsky, S., Layous, K., Chancellor, J., & Nelson, S. K. (2015). Thinking about rumination: The scholarly contributions and intellectual legacy of Susan Nolen-Hoeksema. Annual review of clinical psychology, 11(1), 1-22. https://www.annualreviews.org/content/journals/10.1146/annurev-clinpsy-032814-112733 Teismann, T., & Ehring, T. (2019). Pathologisches Grübeln (Vol. 74). Hogrefe Verlag GmbH & Company KG. Watkins, E. D., Moulds, M., & Mackintosh, B. (2005). Comparisons between rumination and worry in a non-clinical population. Behaviour research and therapy, 43(12), 1577-1585. Praktische Tipps: Wignall, N. (2020). 10 Simple Ways to Stop Overthinking Everything. https://nickwignall.com/overthinking/ Becker, E. S., & Margraf, J. (2008). Vor lauter Sorgen.... Hilfe für Betroffenen von Generalisierter Angststörung (GAS) und deren Angehörige. Weinheim: Beltz. Wahl, K., Ehring, T., Kley, H., Lieb, R., Meyer, A., Kordon, A., ... & Schönfeld, S. (2019). Is repetitive negative thinking a transdiagnostic process? A comparison of key processes of RNT in depression, generalized anxiety disorder, obsessive-compulsive disorder, and community controls. Journal of behavior therapy and experimental psychiatry, 64, 45-53. Querstret, D., & Cropley, M. (2013). Assessing treatments used to reduce rumination and/or worry: A systematic review. Clinical psychology review, 33(8), 996-1009. Wang, S., Lu, M., Dong, X., & Xu, Y. (2025). Does physical activity-based intervention decrease repetitive negative thinking? A systematic review. PLoS One, 20(4), e0319806. Repetitive Negative Thinking transdiag. zu betrachten, ist als Idee nichtneu: 2 Reviews kommen auch schon zu diesem Schluss: Ehring, T., & Watkins, E. R. (2008). Repetitive negative thinking as a transdiagnostic process. International journal of cognitive therapy, 1(3), 192-205. Harvey, A. G., Watkins, E., Mansell, W., & Shafran, R. (2004). Cognitive behavioural processes across psychological disorders. Oxford, UK: Oxford University Press Die Geschichte der Reagans: https://www.spiegel.de/geschichte/attentat-auf-ronald-reagan-a-947145.html https://www.latimes.com/local/obituaries/la-me-joan-quigley-20141024-story.html https://www.nytimes.com/2014/10/25/us/joan-quigley-astrologer-to-a-first-lady-is-dead-at-87.html Redaktion: Andy Hartard Produktion: Murmel Productions

Dr. Harish Kinni, a triple-board-certified emergency medicine and critical care physician and assistant professor at the Mayo Clinic, provides an overview of the fundamentals of ventilator care for emergency department professionals. We will review key modes that we should know, the variables to set, how to adjust them for your patient's needs, and provide troubleshooting tips and tricks for when things suddenly go awry. This is sure to be one of the most helpful chapters of Always on EM, but don't let it take your breath away! CONTACTS X - @AlwaysOnEM; @VenkBellamkonda YouTube - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch Email - AlwaysOnEM@gmail.com REFERENCES & LINKS Swart P, Nijbroek SGLH, Paulus F, Neto AS, Schultz MJ. Sex Differences in Use of Low Tidal Volume Ventilation in COVID-19-Insights From the PRoVENT-COVID Study. Front Med (Lausanne). 2022 Jan 3;8:780005. doi: 10.3389/fmed.2021.780005. PMID: 35300177; PMCID: PMC8923734. McNicholas BA, Madotto F, Pham T, Rezoagli E, Masterson CH, Horie S, Bellani G, Brochard L, Laffey JG; LUNG SAFE Investigators and the ESICM Trials Group. Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study. Eur Respir J. 2019 Oct 17;54(4):1900609. doi: 10.1183/13993003.00609-2019. PMID: 31346004. Swart P, Deliberato RO, Johnson AEW, Pollard TJ, Bulgarelli L, Pelosi P, de Abreu MG, Schultz MJ, Neto AS. Impact of sex on use of low tidal volume ventilation in invasively ventilated ICU patients-A mediation analysis using two observational cohorts. PLoS One. 2021 Jul 14;16(7):e0253933. doi: 10.1371/journal.pone.0253933. PMID: 34260619; PMCID: PMC8279424. Evans, Laura1; Rhodes, Andrew2; Alhazzani, Waleed3; Antonelli, Massimo4; Coopersmith, Craig M.5; French, Craig6; Machado, Flávia R.7; Mcintyre, Lauralyn8; Ostermann, Marlies9; Prescott, Hallie C.10; Schorr, Christa11; Simpson, Steven12; Wiersinga, W. Joost13; Alshamsi, Fayez14; Angus, Derek C.15; Arabi, Yaseen16; Azevedo, Luciano17; Beale, Richard18; Beilman, Gregory19; Belley-Cote, Emilie20; Burry, Lisa21; Cecconi, Maurizio22; Centofanti, John23; Coz Yataco, Angel24; De Waele, Jan25; Dellinger, R. Phillip26; Doi, Kent27; Du, Bin28; Estenssoro, Elisa29; Ferrer, Ricard30; Gomersall, Charles31; Hodgson, Carol32; Hylander Møller, Morten33; Iwashyna, Theodore34; Jacob, Shevin35; Kleinpell, Ruth36; Klompas, Michael37; Koh, Younsuck38; Kumar, Anand39; Kwizera, Arthur40; Lobo, Suzana41; Masur, Henry42; McGloughlin, Steven43; Mehta, Sangeeta44; Mehta, Yatin45; Mer, Mervyn46; Nunnally, Mark47; Oczkowski, Simon48; Osborn, Tiffany49; Papathanassoglou, Elizabeth50; Perner, Anders51; Puskarich, Michael52; Roberts, Jason53; Schweickert, William54; Seckel, Maureen55; Sevransky, Jonathan56; Sprung, Charles L.57; Welte, Tobias58; Zimmerman, Janice59; Levy, Mitchell60. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Critical Care Medicine 49(11):p e1063-e1143, November 2021. | DOI: 10.1097/CCM.0000000000005337  Fan E, Del Sorbo L, Goligher EC, Hodgson CL, Munshi L, Walkey AJ, Adhikari NKJ, Amato MBP, Branson R, Brower RG, Ferguson ND, Gajic O, Gattinoni L, Hess D, Mancebo J, Meade MO, McAuley DF, Pesenti A, Ranieri VM, Rubenfeld GD, Rubin E, Seckel M, Slutsky AS, Talmor D, Thompson BT, Wunsch H, Uleryk E, Brozek J, Brochard LJ; American Thoracic Society, European Society of Intensive Care Medicine, and Society of Critical Care Medicine. An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2017 May 1;195(9):1253-1263. doi: 10.1164/rccm.201703-0548ST. Erratum in: Am J Respir Crit Care Med. 2017 Jun 1;195(11):1540. doi: 10.1164/rccm.19511erratum. PMID: 28459336. Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A, Du B, Aboodi M, Wunsch H, Cecconi M, Koh Y, Chertow DS, Maitland K, Alshamsi F, Belley-Cote E, Greco M, Laundy M, Morgan JS, Kesecioglu J, McGeer A, Mermel L, Mammen MJ, Alexander PE, Arrington A, Centofanti JE, Citerio G, Baw B, Memish ZA, Hammond N, Hayden FG, Evans L, Rhodes A. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19). Crit Care Med. 2020 Jun;48(6):e440-e469. doi: 10.1097/CCM.0000000000004363. PMID: 32224769; PMCID: PMC7176264. Wang W, Scharfstein D, Wang C, Daniels C, Needham D, Brower R, NHLBI ARDS Clinical Network. Estimating the Causal Effect of Low Tidal Volume Ventilation on Survival in Patients with Acute Lung Injury. J R Stat Soc Ser C Appl Stat. 2011. PMC: PMC3197806 Brower RG, Thompson BT, NIH/NHLBI/ARDSNetwork. Tidal volumes in acute respiratory distress syndrome--one size does not fit all. Crit Care Med. 2006. Hager DN, Krishman JA, Hayden D, Brower RG, ARDSNet NIH / NHLBI. Tidal Volume Reduction in Patients with acute Lung Injury When Plateau Pressures Are Not High. Am J Resp Crit Care Med. 2005. Rubenfeld GD, Cooper C, Carter G, Thompson BT, Hudson LD. Barriers to providing lung protective ventilation to patients with acute lung injury. Crit Care Med. 2004. Chatburn RL, El-Khatib M, Mireles-Cabodevila E. A taxonomy for mechanical ventilation: 10 fundamental maxims. Respir Care. 2014 Nov;59(11):1747-63. doi: 10.4187/respcare.03057. Epub 2014 Aug 12. PMID: 25118309. Guo L, Wang W, Zhao N, Guo L, Chi C, Hou W, Wu A, Tong H, Wang Y, Wang C, Li E. Mechanical ventilation strategies for intensive care unit patients without acute lung injury or acute respiratory distress syndrome: a systematic review and network meta-analysis. Crit Care. 2016 Jul 22;20(1):226. doi: 10.1186/s13054-016-1396-0. PMID: 27448995; PMCID: PMC4957383. Rice TW, Wheeler AP, Bernard GR, Hayden DL, Schoenfeld DA, Ware LB, NIH NHLBI ARDS Network. Comparison of the Sp02/FI02 Ratio and the PaO 2/FI02 in Patients with Acute Lung Injury or ARDS. Chest. 2007. Zhang G, Burla MJ, Caesar BB, Falank CR, Kyros P, Zucco VC, Strumilowska A, Cullinane DC, Sheppard FR. Emergency Department SpO2/FiO2 Ratios Correlate with Mechanical Ventilation and Intensive Care Unit Requirements in COVID-19 Patients. West J Emerg Med. 2024 May;25(3):325-331. doi: 10.5811/westjem.17975. PMID: 38801037; PMCID: PMC11112664.   WANT TO WORK AT MAYO? EM Physicians: https://jobs.mayoclinic.org/emergencymedicine EM NP PAs: https://jobs.mayoclinic.org/em-nppa-jobs   Nursing/Techs/PAC: https://jobs.mayoclinic.org/Nursing-Emergency-Medicine EMTs/Paramedics: https://jobs.mayoclinic.org/ambulanceservice All groups above combined into one link: https://jobs.mayoclinic.org/EM-Jobs

Contributor: Alec Coston, MD Educational Pearls: For patients presenting to the emergency room with hypertension, clinicians should determine if it is isolated and uncomplicated, or involves comorbidities with more complex underlying pathophysiology.  For uncomplicated and isolated hypertension, first-line treatment is thiazide diuretics.  How do thiazide diuretics work to treat hypertension? Thiazide diuretics work by blocking sodium and chloride resorption in the kidneys.  “Where sodium goes, water follows,” thus promoting diuresis and lowering blood pressure. Examples of thiazide diuretics and their benefits? Hydrochlorothiazide (HCTZ): First-line medication in uncomplicated and chronic hypertensive states. Cheaper and fewer significant adverse effects compared to chlorthalidone. HCTZ can be associated with decreased risk of stroke and myocardial infarction. However, for more complicated hypertension, especially in the setting of heart failure, Angiotensin Converting Enzyme (ACE) Inhibitors should be considered.  How do ACE Inhibitors manage blood pressure? The body's kidneys drive the Renin-Angiotensin-Aldosterone-System (RAAS) to regulate blood pressure. It is easiest to understand RAAS as being pro-hypertensive as a response to decreased renal perfusion. As renal perfusion decreases, renin is released and activates angiotensin I, which is converted by ACE to Angiotensin II, which causes release of aldosterone. ACE Inhibitors prevent the conversion of Angiotensin I to Angiotensin II, thus decreasing the kidneys' production of Angiotensin II and Aldosterone levels. Why, in the context of heart failure, are ACE Inhibitors preferred? In heart failure, especially left-sided or left-ventricular heart failure, a vicious cycle can develop wherein the left ventricle fails to perfuse the kidneys due to over-dilation. The kidneys are hypoperfused and activate RAAS to try to retain volume and increase peripheral vasoconstriction, promoting renal perfusion. The increase in blood pressure puts further strain on the heart, thereby further decreasing cardiac output. The cycle develops, and extremely elevated blood pressures can develop. ACE Inhibitors can directly block this cycle, hence their preference in heart failure. Big takeaway? In uncomplicated hypertensive patients, consider thiazide diuretics. When comorbidities, especially heart failure, are introduced, then consider ACE Inhibitors. References Carey RM, Moran AE, Whelton PK. Treatment of Hypertension: A Review. JAMA. 2022;328(18):1849-1861. doi:10.1001/jama.2022.19590 Fan M, Zhang J, Lee CL, Zhang J, Feng L. Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. Nature. 2023;614(7949):788-793. doi:10.1038/s41586-023-05718-0 Hripcsak G, Suchard MA, Shea S, et al. Comparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension. JAMA Internal Medicine. 2020;180(4):542-551. doi:10.1001/jamainternmed.2019.7454 Yu D, Li JX, Cheng Y, et al. Comparative efficacy of different antihypertensive drug classes for stroke prevention: A network meta-analysis of randomized controlled trials. PLoS One. 2025;20(2):e0313309. doi:10.1371/journal.pone.0313309 Summarized by Dan Orbidan, OMS2 | Edited by Dan Orbidan & Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/  

I interviewed 60 Brits to debunk one of psychology's greatest myths. Priming is one of the best-known biases in behavioural science. Kahneman mentions it 35 times in his best-selling book Thinking Fast and Slow. And yet, I'm not convinced it really works. In five separate experiments, I tested it. Does priming work, or is it a myth?  The studies:  Authenticity study: https://ibb.co/5W14DM2N Creativity study: https://ibb.co/FbxxNMDf Guilty study: https://ibb.co/XrTLXrY4 Anchoring + priming study: https://ibb.co/99LLw7G9 Reading time study: https://ibb.co/LDYc18yF ---  Subscribe to the (free) Nudge Newsletter: https://nudge.ck.page/profile Connect on LinkedIn: https://www.linkedin.com/in/phill-agnew-22213187/ Watch Nudge on YouTube: https://www.youtube.com/@nudgepodcast/ Learn more about Voxpopme: https://www.voxpopme.com/ ---  Sources:  Bargh, J. A., Chen, M., & Burrows, L. (1996). Automaticity of social behavior: Direct effects of trait construct and stereotype activation on action. Journal of Personality and Social Psychology, 71(2), 230–244. Chernev, A. (2011). Semantic anchoring in sequential evaluations of vices and virtues. Journal of Consumer Research, 37(5), 761–774. Doyen, S., Klein, O., Pichon, C. L., & Cleeremans, A. (2012). Behavioral priming: It's all in the mind, but whose mind? PLoS ONE, 7(1), e29081. Fitzsimons, G. J., Chartrand, T. L., & Fitzsimons, G. M. (2008). Automatic effects of brand exposure on motivated behavior: How Apple makes you “think different”. Journal of Consumer Research, 35(1), 21–35. Goldsmith, K., Cho, E., & Dhar, R. (2012). Priming creativity: The effects of subliminal priming on creative problem solving. In Z. Gürhan-Canli, C. Otnes, & R. Zhu (Eds.), Advances in Consumer Research (Vol. 40, pp. 472–473). Association for Consumer Research. Kahneman, D. (2011). Thinking, fast and slow. Farrar, Straus and Giroux. Kahneman, D. (2012, September 26). A letter to the priming research community [Open email].

Chimpanzees use medicinal plants for first aid and hygieneResearchers have observed wild chimpanzees seeking out particular plants, including ones known to have medicinal value, and using them to treat wounds on themselves and others. They also used plants to clean themselves after sex and defecation. Elodie Freymann from Oxford University lived with the chimpanzees in Uganda over eight months and published this research in the journal Frontiers in Ecology and Evolution.Why this evolutionary dead end makes understanding extinction even more difficult540 million years ago, there was an explosion of animal diversity called the Cambrian explosion, when nature experimented with, and winnowed many animal forms into just a few. A new discovery of one of the unlucky ones that didn't make it has deepened the mystery of why some went extinct, because despite its strangeness, it shows adaptations common to many of the survivors. Joseph Moysiuk, curator of paleontology and geology at the Manitoba Museum helped identify the fossil, and published on it in Royal Society Open Science A quantum computer demonstrates its worth by solving an impossible puzzleImagine taking a sudoku puzzle, handing bits of it to several people, putting them in separate rooms, and asking them to solve the puzzle. A quantum computer using the weird phenomenon of “entanglement” was able to do something analogous to this, which serves as evidence that it really is exploiting quantum strangeness, and could be used for more practical purposes. David Stephen, a physicist at the quantum computing company Quantinuum, and colleagues from the University of Boulder published on this finding in Physical Review Letters.Roadkill shows that most mammals have fluorescent furA researcher who used a range of mammal and marsupial animals killed by vehicles, has demonstrated that the fur of many of these animals exhibit biofluorescence – the ability to absorb light and re-emit it in different wavelengths. They were able to identify some of the fluorescent chemicals, but don't know why these animals would glow like this. Zoologist Linda Reinhold observed bright colours such as yellow, blue, green and pink on Australian animals like the bandicoot, wallaby, tree-kangaroo, possums and quolls. Their research was published in the journal PLOS One.Science suggests humans are not built for the information ageWe are living in the age of information. In fact, we're drowning in it. Modern technology has put vast amounts of information at our fingertips, and it turns out that science is showing that humans just aren't that good at processing all that data, making us vulnerable to bias, misinformation and manipulation.Producer Amanda Buckiewicz spoke to:Friedrich Götz, an Assistant Professor of Psychology at the University of British Columbia.Vasileia Karasavva, a PhD student in the Department of Psychology at the University of British Columbia.Timothy Caulfield, professor in the Faculty of Law and the School of Public Health at the University of Alberta, and was the Canada Research Chair in Health Law and Policy from 2002 - 2023.Eugina Leung, an assistant professor of marketing at the A.B. Freeman School of Business at Tulane University.Jonathan Kimmelman, a medical ethicist based at McGill University.

Mental health information on social media can be both revelatory and misleading. How do clinicians and their patients make sense of it?TikTok and other social media sites are full of mental health content—often short, grabby, first-person videos detailing symptoms for conditions like ADHD and autism. But what does this mean for teens and young adults who spend hours a day scrolling?A new study published in PLOS One analyzes the 100 most viewed TikTok videos about ADHD to assess both how accurate they are and how young people respond to them. Researchers found that about half of the videos were inaccurate or missing key context, and that the more TikToks young adults watched, the less critical they were of the content.For some, watching social videos about mental health conditions led them to better understand themselves and eventually get a proper diagnosis and treatment. For others it made them consider if they have conditions they don't meet the diagnostic criteria for.Host Flora Lichtman talks with the lead author of the ADHD TikTok study, Vasileia Karasavva, a PhD Student in clinical psychology at the University of British Columbia; and Dr. Jennifer Katzenstein, director of psychology, neuropsychology, and social work at Johns Hopkins All Children's Hospital in St. Petersburg, Florida.Transcripts for each segment will be available after the show airs on sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.