Podcasts about PLOS One

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Latest podcast episodes about PLOS One

Beekeeping Today Podcast
[Bonus] Short - Dr. Dewey Caron: Fat Bees and Overwintering Success

Beekeeping Today Podcast

Play Episode Listen Later Sep 10, 2025 19:57


In this BTP Short, Dr. Dewey Caron shares another of his “audio postcards,” this time exploring the critical role of fat bees—also known as diutinus bees—in helping colonies survive winter. Dewey explains how these long-lived worker bees differ from their summer sisters, with enlarged fat bodies, higher protein reserves, and lower juvenile hormone levels, all tied to the key blood protein vitellogenin. Drawing on published research papers, Dewey highlights how environmental cues such as declining pollen, temperature, and daylight trigger the production of winter bees, and how clustering helps colonies thermoregulate through the cold months. He emphasizes that strong, heavy colonies going into winter are far more likely to survive than weak or light ones. For beekeepers, Dewey stresses the importance of continuous Varroa control throughout the season, fall feeding to ensure sufficient carbohydrate and protein stores, and combining weaker units when necessary. He also discusses drone eviction, stock influences, and climate change modeling that suggests warmer falls may disrupt the balance of winter bee production and survival. This episode provides science-based insights and practical recommendations to help beekeepers communicate with their colonies—ensuring not only fat bees, but fat, well-prepared colonies for overwintering success. Websites and Links mention in the episode: Döke, Mehmet A. M. Frazier, and C.  Grozinger, 2015 “Overwintering honey bees: biology and management,” Current Opinion in Insect Science. Mehmet Ali Döke, Christina M. Grozinger. 2017. Pheromonal control of overwintering physiology and success in honey bees (Apis mellifera, L.) Döke, Mehmet Ali, CM McGrady, M. Otieno, CM Grozinger, M Frazier. 2019. Colony size, rather than geographic origin of stocks, predicts overwintering success in honey bees (Hymenoptera: Apidae) in the Northeastern United States. J. Econ. Entomology 112 (2), 525-533, DOI: 10.1093/jee/toy377 Stephanie Feliciano-Cardona, †Mehmet Ali Döke, Janpierre Ale man,Jose Luis Agosto-Rivera. Christina M. Grozinger and Tugrul Giray 2020. Honey Bees in the Tropics Show Winter Bee-Like Longevity in Response to Seasonal Dearth and Brood Reduction. Front. Ecol. Evol., 8.  https://doi.org/10.3389/fevo.2020.571094 Somerville, Doug (2005) Fat Bees Skinny Bees, A manual on honey bee nutrition for beekeepers., Australia. Available on the Web at https://www.agrifutures.com.au/wp-content/uploads/publications/05-054.pdf   https://rirdc.infoservices.com.au/downloads/05-054 Kirti Rajagopalan, Gloria DeGrandi-Hoffman, Matthew Pruett, Vincent P. Jones, Vanessa Corby-Harris, Julien Pireaud, Robert Curry, Brandon Hopkins & Tobin D. Northfield. 2024. Warmer autumns and winters could reduce honey bee overwintering survival with potential risks for pollination services. Scientific Reports volume 14, Article number: 5410 (2024) For homework Ashley L. St. Clair , Nathanael J. Beach, Adam G. Dolezal. 2022.  Honey bee hive covers reduce food consumption and colony mortality during overwintering. Plos One. https://doi.org/10.1371/journal.pone.0266219  SBGM videos:  https://mail.google.com/mail/u/0/#inbox/FMfcgzQcpKmXBhglCpthGSBzvHVLlSfp   Brought to you by Betterbee – your partners in better beekeeping. ______________ Betterbee is the presenting sponsor of Beekeeping Today Podcast. Betterbee's mission is to support every beekeeper with excellent customer service, continued education and quality equipment. From their colorful and informative catalog to their support of beekeeper educational activities, including this podcast series, Betterbee truly is Beekeepers Serving Beekeepers. See for yourself at www.betterbee.com Copyright © 2025 by Growing Planet Media, LLC

Autism Parenting Secrets
AVOID THIS Popular Drug To Protect Development

Autism Parenting Secrets

Play Episode Listen Later Sep 6, 2025 54:49


Welcome to Episode 272 of Autism Parenting Secrets.This week, we're talking about a medicine almost every parent has used. For decades, doctors have recommended it for fevers, ear infections, even after vaccines. It's long been considered safe.But compelling evidence shows it's not nearly as safe as we've been told—especially for babies and young children under stress.My guest is Dr. William Parker. He is distinguished, highly credentialed, and deeply passionate about protecting children. After earning his PhD in Chemistry, he spent nearly 30 years at Duke University studying biochemistry, microbiology, and immunology. He's best known for discovering the function of the human appendix—a safe-house for bacteria—and for the last decade, he's focused on how acetaminophen, when combined with oxidative stress, impacts brain development. He's published more than 150 peer-reviewed papers, and his work points to this drug playing a major role in the rise of autism.This is a conversation parents need to hear. Dr. Parker is substantive, credible, and unwavering in his pursuit of the truth. It's not about fear—it's about clarity and better choices.The secret this week is…AVOID THIS Popular Drug To Protect DevelopmentYou'll Discover:The Hidden Link First Exposed in 2008 (4:51)How Acetaminophen + Oxidative Stress = Trouble For Susceptible Kids (15:29)The Timeline That Matches The Rise of Autism (23:26)The Flawed Assumptions in Many Scientific Studies (26:50)Practical Next Steps Parents Can Take (45:53)The Actual MECHANISM That Harms Brain Cells (51:07)About Our Guest:William Parker earned a PhD in Chemistry in 1992 and studied biochemistry, microbiology, and immunology at Duke University for almost 30 years before starting WPLab, a private, non-profit research and education corporation, in 2021. Best known for the discovery of the function of the human appendix (a safe-house for bacteria), Dr. Parker has spent almost a decade studying the impact of acetaminophen combined with oxidative stress on neurodevelopment. He has published more than 150 peer-reviewed papers, including work in PLoS One, the European Journal of Pediatrics, Minerva Pediatrics, and Clinical and Experimental Pediatrics. WPLab scientists have concluded that many, if not most, cases of autism are a chemically induced injury caused by exposure of susceptible babies and children to acetaminophen.References In This Episode:Learn more about Dr. Parker's work: PreventAutism.org and www.wplaboratory.orgAdditional Resources:To learn more about personalized 1:1 support, go to www.elevatehowyounavigate.comTake The Quiz: What's YOUR Top Autism Parenting Blindspot?If you enjoyed this episode, share it with your friends.

Rio Bravo qWeek
Episode 202: BPA Overview

Rio Bravo qWeek

Play Episode Listen Later Sep 5, 2025 22:08


Episode 202: BPA OverviewWritten by Cameron Carlisle, MSIV, Ross University School of Medicine. Comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice._____________________Arr: Welcome to another episode of Rio Bravo qWeek. My name is Hector Arreaza, I'm an associate program director and faculty in the Rio Bravo Family Medicine Residency Program. Today my co-host is Cameron Carlisle, who is a 4th-year medical student finishing his last rotation of med school. Welcome, Cameron, please introduce yourself.Arreaza: What are we talking about today, Cameron?Cam: Dr. Arreaza, did you know you're probably carrying around a chemical in your body that mimics estrogen? In fact, a 2004 CDC study found over 92% of Americans had detectable levels of Bisphenol A (BPA) in their urine. Today's topic is BPA.BPA is everywhere: receipts, water bottles, canned foods, baby bottles, and even our dental fillings. It's one of the most ubiquitous endocrine-disrupting chemicals (EDCs), which interferes with the body's hormone systems. That's why today's episode is about making the invisible visible. Our goals for today's podcast:Break down what BPA isShow how it affects the human bodyExplain how you and your patients can limit exposureEmpower both clinicians and the public with real, practical informationArreaza: Thanks for clarifying BPA today. It seems like we always have to learn about a new carcinogen or toxic substance that we are exposed to. I remember when I was a child, Yellow #5 became very concerning for the general public but it is still being used in our foods. So, it's good you are talking about this. What Is BPA?Cam: Bisphenol A (BPA) is an industrial chemical used since the 1950s, primarily in polycarbonate plastics and epoxy resins. It makes plastic clear, and is often found in:Water bottlesCanned food liningsBaby bottles (pre-2012)Takeout containersCash register receiptsDental sealantsArreaza: So, I've seen the “BPA-free” labels many times, and today I'm glad you are going to shed some light about it.Cam: What's alarming is that BPA leaches out of these products, especially when exposed to heat, acidity, or repeated use. A Harvard study found that people who drank from plastic bottles for just one week had a 69% increase in urinary BPA levels (Carwile & Michels, 2009).Arreaza: That's a lot of people 69%. Section 3: What happens when BPA gets into our body? How BPA Works in the BodyCam: BPA is classified as an endocrine disruptor, meaning it can bind to estrogen receptors and mimic or block natural hormone functions.It affects:Reproductive systems (both male and female)NeurodevelopmentThyroid signalingPancreatic β-cell functionMetabolism and fat storageEven low-dose exposure can disrupt cellular function. BPA acts as a xenoestrogen (foreign estrogen) and has been shown to alter DNA methylation, leading to epigenetic changes that persist across generations (Manikkam et al., 2013).Arreaza: So, BPA can cause epigenetic changes that can be inherited. BPA can persist for generations in your offspring.BPA's Health Impacts – What the Research SaysHere's where it gets serious. Let's go system-by-system:1. Reproductive HealthFemales: Linked to PCOS, infertility, and early puberty (Peretz et al., 2014).Males: Reduced sperm count and motility; altered testosterone levels.2. Pregnancy and Birth OutcomesIncreased risk of preterm birth, gestational diabetes, and low birth weight (Snijder et al., 2013).Studies show BPA crosses the placenta, directly affecting the fetus.3. Neurological DevelopmentAssociated with ADHD, anxiety, and impaired executive function in children exposed in utero (Mustieles et al., 2015).4. Metabolism and DiabetesBPA exposure is linked to insulin resistance, obesity, and type 2 diabetes, even at low doses (Lang et al., 2008).5. CancerAnimal and human data link BPA to increased risk of breast and prostate cancer via estrogenic mechanisms.6. MortalityA 2020 JAMA study found individuals with higher BPA levels had a 49% increased risk of all-cause mortality compared to those with lower levels (Gao et al., 2020).Arreaza: You are scaring me. I wonder what my BPA level is in my blood. Actually, BPA can be detected in urine. This is the most common approach for population-level biomonitoring, because BPA and its metabolites are mostly excreted in urine. Studies have found that BPA is present in most people, even up to 85–99% in large cohorts. Cam: That's literally everyone. Sources of BPA ExposureLet's talk about things we use every day:Thermal receipts (like from Target or Starbucks): BPA can transfer onto your skin and be absorbed, especially if your hands are wet or lotioned.Canned soups: One study showed that eating canned soup daily for five days led to a 1000% increased urinary BPA levels (Carwile et al., 2011).Plastic water bottles left in the car on hot days or plastic food trays for microwaving = chemical leaching.Baby bottles and pacifiers (pre-2012): primary concern for newborns.Arreaza: So, Cameron, you were exposed to BPA as a baby.Cam: Here's the jaw-dropper: We ingest up to 5 grams of plastic per week, roughly the weight of a credit card (WWF, 2019; University of Newcastle). This includes microplastics like BPA, which enter through food, water, and air.Arreaza: So, it translates into 40 lbs of plastic in a lifetime, by age 70. What can we do as family physicians?Family Medicine and Preventive CareAs family physicians, we are at the frontlines of prevention. Our role includes:Anticipatory guidance: during prenatal visits, well-child visits, and chronic disease managementScreening opportunities: ask about storage habits, microwave use, and receipt handlingEnvironmental health counseling: AAFP recommends addressing endocrine disrupting chemicals (EDCs) when relevant to a patient's concerns.It's not just about treating diabetes or obesity. It's about recognizing that environmental exposure may be a root cause.Arreaza: Prevention is my favorite topic!Cam: One helpful clinical practice:Arreaza: What else can we do to reduce BPA exposure?Practical Steps to Reduce BPAHere's what patients and doctors alike can do today:Switch to BPA-free products, but be careful, as replacements like BPS or BPF may also be harmful (Rochester & Bolden, 2015).Avoid microwaving or dishwashing plastic containers.Use digital receipts.Filter tap water using carbon filters, which can reduce microparticle ingestion.Choose fresh produce over canned goods when possible.Also, wash your hands after handling receipts, especially before eating or touching your face.Arreaza: What is our government doing to protect us?Public Health and Policy UpdatesRegulations are slowly catching up:The FDA banned BPA in baby bottles and sippy cups in 2012.The European Union has stricter limits, and France banned BPA in all food packaging in 2015.California's Proposition 65 requires BPA warning labels.Arreaza: Proposition 65, passed by direct voter initiative in 1986, “WARNING: This product contains chemicals known to the State of California to cause cancer and birth defects or other reproductive harm.”Arreaza: The FDA is planning to phase out petroleum-based food dyes (certified color additives) from the American food supply – marking a significant milestone in the efforts to protect the public. Cam: Many products still contain BPA analogs (BPS, BPF), which are not yet well-regulated.This is where clinician advocacy matters, where we can guide public opinion and support legislative change.Arreaza: So, millions of pounds of toxic substances are produced by many industries in the US. As physicians, we have to stay informed and update our patients.Cameron: How can we wrap up this episode?Conclusion and TakeawaysBPA is a hormone disruptor hiding in plain sight.People are exposed to BPA every day, but small lifestyle changes can dramatically reduce it.Family medicine has a role in education, prevention, and advocacy.Let's all be part of the solution for our health and future generations. Stanley (tumblers) are not sponsoring this episode, and we did not receive any money from them. Arreaza: That's it for today's episode of Rio Bravo qWeek. If you enjoyed this episode, share it with a colleague or medical student who may need to know about BPA. I'm Dr. Arreaza, signing off.Cameron: Hopefully, in the future I will talk to you about more endocrine disrupting chemicals. Thanks for listening._____________________Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Carwile, J. L., & Michels, K. B. (2009). Urinary bisphenol A and obesity: NHANES 2003–2006. Environmental Research, 111(6), 825–830.Carwile, J. L., et al. (2011). Canned soup consumption and urinary bisphenol A: A randomized crossover trial. JAMA, 306(20), 2218–2220.Centers for Disease Control and Prevention (CDC). (2004). Fourth National Report on Human Exposure to Environmental Chemicals.Gao, X., et al. (2020). Urinary bisphenol A and mortality risk. JAMA Network Open, 3(8), e2011620.Lang, I. A., et al. (2008). Association of urinary bisphenol A with medical disorders and laboratory abnormalities in adults. JAMA, 300(11), 1303–1310.Manikkam, M., et al. (2013). Epigenetic transgenerational inheritance of disease. PLOS ONE, 8(1), e55387.Mustieles, V., et al. (2015). Bisphenol A and neurodevelopmental outcomes in children. Environmental Health Perspectives, 123(7), 689–695.Peretz, J., et al. (2014). Bisphenol A and reproductive health. Environmental Health Perspectives, 122(8), 775–786.Rochester, J. R., & Bolden, A. L. (2015). Bisphenol S and F: A systematic review. Environmental Health Perspectives, 123(7), 643–650.Snijder, C. A., et al. (2013). Fetal growth and prenatal exposure to bisphenol A. Environmental Health Perspectives, 121(3), 393–398.World Wildlife Fund (WWF). (2019). No Plastic in Nature: Assessing Plastic Ingestion from Nature to People.University of Newcastle (Australia). (2019). Human Consumption of Microplastics.Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

Wissensnachrichten - Deutschlandfunk Nova
Veggie-Hund, CO2-Speicherung, Klo-Handy

Wissensnachrichten - Deutschlandfunk Nova

Play Episode Listen Later Sep 4, 2025 5:12


Die Themen in den Wissensnachrichten +++ Veggie-Hundefutter schneidet in Tests ähnlich ab wie fleischhaltiges +++ Unser Planet hat nur begrenzte Kapazitäten für die CO2-Speicherung +++ Warum zu viel Handy auf dem Klo keine gute Idee ist +++**********Weiterführende Quellen zu dieser Folge:Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK. Plos One, 03.09.2025A prudent planetary limit for geologic carbon storage. Nature, 03.09.2025Smartphone use on the toilet and the risk of hemorrhoids. Plos One, 03.09.2025Is there a relationship between organisational climate and job satisfaction? A view from a systematic review and meta-analysis. World Review of Entrepreneurship, Management and Sustainable Development, 01.09.2025Colorless and unidirectional diffractive-type solar concentrators compatible with existing windows. Photonix, 28.07.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

The Scenic Route
Does Body Size Affect Your Grades? The Latest Truth About Fat Bias in Education

The Scenic Route

Play Episode Listen Later Sep 2, 2025 18:50 Transcription Available


Can a student's body size affect their grades? Research says yes. In this episode of The Scenic Route, Jen explores how fat bias and socioeconomic bias shape grades, opportunities, and self-worth.You'll hear:A personal story of how weight stigma shows up in healthcare.A German study of 14,000 students showed that overweight and lower-income kids receive lower grades than equally capable peers.Why grades often reflect compliance, neatness, and bias more than actual learning.How to judge whether a study is credible using reliability, objectivity, and validity and why validity is the trickiest.Practical steps for parents, teachers, and students to challenge fatbias in schools and beyond.Grades don't just decide report cards. They decide futures. When body size and class bias affect grades, kids are taught that some people matter less.This episode is a call to question those systems and to push for a world where all kids can thrive.

Nudge
This small change can make a politician electable

Nudge

Play Episode Listen Later Sep 1, 2025 25:36


What determines who you vote for?  You probably think it's due to rational reasons. Economy. Sustainability. Immigration. Growth.  But research shows that your choice of vote isn't as logical as you might expect.  In fact, all of our votes can be swayed by a largely irrelevant factor.  And this factor can be used to change what we eat, wear, drink and buy.  Hear how, on today's episode of Nudge with Phil Graves. ---  Phil's book: https://shorturl.at/kzAta Phil's consultancy: https://www.philipgraves.net/consultancy/ Subscribe to the (free) Nudge Newsletter: https://nudge.ck.page/profile  Connect on LinkedIn: https://www.linkedin.com/in/phill-agnew-22213187/  Watch Nudge on YouTube: https://www.youtube.com/@nudgepodcast/ --- Today's sources: Cialdini, R. B., Reno, R. R., & Kallgren, C. A. (1990). A focus theory of normative conduct: Recycling the concept of norms to reduce littering in public places. Journal of Personality and Social Psychology, 58(6), 1015–1026. Davis, C. J., Bowers, J. S., & Memon, A. (2011). Social influence in televised election debates: A potential distortion of democracy. PLoS ONE, 6(3), e18154. Latané, B., & Darley, J. M. (1968). Group inhibition of bystander intervention in emergencies. Journal of Personality and Social Psychology, 10(3), 215–221. Martin, S. J. (2024). Influence at work: Capture attention, connect with others, convince people to act. The Economist Books (Pegasus Books). Tanner, R. J., Ferraro, R., Chartrand, T. L., Bettman, J. R., & Van Bagren, R. (2008). Of chameleons and consumption: The impact of mimicry on choice and preferences. Journal of Consumer Research, April. Trott, D. (2023). Crossover creativity: Real-life stories about where creativity comes from. Harriman House.

Wissensnachrichten - Deutschlandfunk Nova
Zufriedenheit, Gewitter, Hummeln

Wissensnachrichten - Deutschlandfunk Nova

Play Episode Listen Later Aug 28, 2025 6:25


Die Themen in den Wissensnachrichten: +++ Junge Erwachsene sind deutlich unglücklicher geworden +++ Durch Klimawandel mehr Superzellen-Gewitter in Europa +++ Hummeln folgen Ernährungsplan +++**********Weiterführende Quellen zu dieser Folge:The declining mental health of the young and the global disappearance of the unhappiness hump shape in age, Plos One 27.08. 2025European supercell thunderstorms—A prevalent current threat and an increasing future hazard. Science Advances, 27.08. 2025Nutrient niche dynamics among wild pollinators, Proceedings of the Royal Society B, 27.08. 2025The evolution of hominin bipedalism in two steps, Nature, 27.08. 2025Declines of ebony and ivory are inextricably linked in an African rainforest, Science Advances 27.08. 2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

The Made to Thrive Show
Light Up Your Life: Mastering the Light Diet to Combat Chronic Diseases, Enhance Sleep, and Unlock Longevity Secrets with Circadian Pioneer Dr. Martin Moore-Ede, MD

The Made to Thrive Show

Play Episode Listen Later Aug 27, 2025 51:03


Your eyes are not cameras—they are clocks. Every cell and organ in your body is orchestrated by the light you let in, making light the most powerful regulator of health. More than ever, I believe the “light diet” is a foundational lifestyle change in the fight against chronic disease. That's why today's guest is one of the most important I've had—a true pioneer in the science of light and health.Dr. Martin Moore-Ede is a world-renowned circadian biology expert with over four decades of research on how light affects sleep, fatigue, and chronic diseases. As a former Harvard Medical School professor, he helped discover the brain's master clock—the suprachiasmatic nucleus—and authored the bestselling The Clocks That Time Us. In 1983, he founded CIRCADIAN®, a global firm optimizing 24/7 workforce performance, and later launched CIRCADIAN Light and CIRCADIAN ZircLight to counter the health risks of artificial lighting.In this episode, we explore:How proper light exposure can increase lifespan by up to five years—and how being “dumb with light” is now correlated with everything from cancer and diabetes to autoimmune and psychiatric disorders.When to wake up, how much outdoor light we need daily, the massive difference in lux between indoor and outdoor light, and the critical role of the brain's internal clock.Why early sunlight matters, and how flawed studies distorted our understanding of sunlight and cataracts.The rise in breast cancer since widespread electrification—now 70x more common.How hospital window placement can influence recovery from depression and anxiety by up to 50%.Why Dr. Moore-Ede gets outside every day—rain, sun, or snow—without sunglasses or eyewear.Whether you're new to circadian science or already light-aware, this episode will shift how you think about health.Contact and Resources: Website – thelightdoctor.com Website – bluesafe24.com Website – circadianlight.orgReferenced Studies Mentioned:Gbyl K et al. (2016). Southeast-facing hospital rooms and faster discharge. Neuropsychobiology.Farahmand B et al. (2009). Golf and reduced mortality. Scand J Med Sci Sports.Boubekri M et al. (2014). Daylight improves health and sleep in office workers. J Clin Sleep Med.Teicher MH et al. (2023). Bright light therapy boosts brain function in adolescents. PLoS One.Support the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/

Nutritotal Cast
Probióticos e Saúde da Mulher

Nutritotal Cast

Play Episode Listen Later Aug 26, 2025 15:48


Infecções de repetição, como candidíase e vaginose, afetam a qualidade de vida de milhões de mulheres. E se a chave para a prevenção e o tratamento estiver em um ecossistema muitas vezes esquecido? Neste terceiro episódio, o Dr. Dan Waitzberg e a Dra. Barbara Peters exploram o fascinante universo da microbiota vaginal.Descubra como os lactobacilos atuam como uma linha de defesa natural, como os probióticos podem restaurar esse equilíbrio e quais os benefícios para mulheres na menopausa.ReferênciasHan Y, Liu Z, Chen T. Role of Vaginal Microbiota Dysbiosis in Gynecological Diseases and the Potential Interventions. Front Microbiol. 2021 Jun 18;12:643422. doi: 10.3389/fmicb.2021.643422. PMID: 34220737; PMCID: PMC8249587.Gupta S, Kakkar V, Bhushan I. Crosstalk between Vaginal Microbiome and Female Health: A review. Microb Pathog. 2019 Nov;136:103696. doi: 10.1016/j.micpath.2019.103696. Epub 2019 Aug 23. PMID: 31449855.Lewis FMT, Bernstein KT, Aral SO. Vaginal Microbiome and Its Relationship to Behavior, Sexual Health, and Sexually Transmitted Diseases. Obstet Gynecol. 2017 Apr;129(4):643-654. doi: 10.1097/AOG.0000000000001932. PMID: 28277350; PMCID: PMC6743080.Rezazadeh MB, Zanganeh M, Jarahi L, Fatehi Z. Comparative efficacy of oral and vaginal probiotics in reducing the recurrence of bacterial vaginosis: a double-blind clinical trial. BMC Womens Health. 2024 Oct 26;24(1):575. doi: 10.1186/s12905-024-03418-z. PMID: 39462408; PMCID: PMC11515199.Hertz FB, Holm JB, Pallejá A, Björnsdóttir MK, Mikkelsen LS, Brandsborg E, Frimodt-Møller N. Vaginal microbiome following orally administered probiotic. APMIS. 2022 Oct;130(10):605-611. doi: 10.1111/apm.13261. Epub 2022 Jul 25. PMID: 35801409; PMCID: PMC9540456.Hertz FB, Holm JB, Pallejá A, Björnsdóttir MK, Mikkelsen LS, Brandsborg E, Frimodt-Møller N. Vaginal microbiome following orally administered probiotic. APMIS. 2022 Oct;130(10):605-611. doi: 10.1111/apm.13261. Epub 2022 Jul 25. PMID: 35801409; PMCID: PMC9540456.Kim JM, Park YJ. Probiotics in the Prevention and Treatment of Postmenopausal Vaginal Infections: Review Article. J Menopausal Med. 2017 Dec;23(3):139-145. doi: 10.6118/jmm.2017.23.3.139. Epub 2017 Dec 29. PMID: 29354612; PMCID: PMC5770522.Silva VF, Refinetti P, Vicariotto F, Baracat EC, Soares Junior JM. Oral probiotics and vaginal microbiome in post-menopause women: an opinion for the improvement of natural therapies in gynecology. Rev Assoc Med Bras (1992). 2024 Jan 5;70(2):e702EDIT. doi: 10.1590/1806-9282.702EDIT. PMID: 38198300; PMCID: PMC10768674.https://bhbfood.com/noticias/iff-health-sciences-conquista-aprovacao-da-anvisa-para-probiotico/Petrova MI, van den Broek M, Balzaretti S, et al. Lactobacillus crispatus dominates healthy vaginal microbiota and inhibits pathogens. Microbiome. 2017;5:74.Grin PM, Kowalewska PM, Alhasson F, et al. Probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 for genitourinary health in women. Eur J Clin Microbiol Infect Dis. 2013;33(6):917–922.Verdenelli MC, Coman MM, Ghelardi E, et al. Lactobacillus acidophilus LA-14 role in vaginal health: adhesion and acidification. Probiotics Antimicrob Proteins. 2015;7(2):114–120.Swidsinski A, Mendling W, Loening-Baucke V, et al. Biofilm of Lactobacillus gasseri in healthy and diseased vagina. PLoS One. 2018;13(5):e0194214.

Authentic Biochemistry
Metabolic Zonation and the Anabolic/Catabolic DEOSenescence and the Immune Response VIIAUTHENTIC BIOCHEMISTRY PODCASTDr Daniel J Guerra22Aug25

Authentic Biochemistry

Play Episode Listen Later Aug 23, 2025 81:40


ReferenceseLife 2020;9:e55828 Int J Mol Sci. 2019 Mar; 20(5): 1223.PLoS One. 2014 Nov 25;9(11):e113939Guerra, DJ.2025. Unpublished Lectures.Oncotarget. 2017 Aug 22; 8(34):55967–55983The Journal of Biological Chemistry2012.287, 40924-40937.Lennon/McCartney, Harrison. 1967. SPLHCB lp. BEATLEShttps://music.youtube.com/playlist?list=OLAK5uy_k0N28ttgCjdEqyy02W7h0v1Kg78hs9AnM&si=OvggJwx7xHkB4vaZGreen, C McVie, J. McVie, Fleetwood, Spencer Welch. 1971 Future Games, lp. Fleetwood Machttps://music.youtube.com/playlist?list=OLAK5uy_myXM7dOObGkQ9rtg96p8QDy_mvV_3Nwt0&si=zZrLBLHHYbgF2-gT Strauss, R. 1896. Also Sprach Zarathustra. OP 30.https://music.youtube.com/playlist?list=OLAK5uy_lcbYBHtM1a-0cclaB_xMKI9e9Efma3OkQ&si=FQm7nzrxNPZKNZiu

The Breast Cancer Recovery Coach
#425 Stress After Breast Cancer - Why Supplements Alone Wont Heal You

The Breast Cancer Recovery Coach

Play Episode Listen Later Aug 22, 2025 32:12


Stress isn't just “in your head”—it changes your biology. It depletes nutrients like magnesium, vitamin C, B vitamins, and zinc, and keeps your body in survival mode. Supplements can help, but they won't heal you if the root cause—stress—remains. In this episode, I talk about why stress management is as critical as nutrition, how CBT and EMDR support your healing, and why lab testing matters before wasting money on supplements.   References from this episode: Juster R-P, McEwen BS, Lupien SJ. (2020). Allostatic load and allostatic overload: Clinical implications. Frontiers in Behavioral Neuroscience. https://doi.org/10.3389/fnbeh.2020.00046  Singewald N, et al. (2004). Magnesium-deficient diet alters anxiety-related behavior in mice. Journal of the American College of Nutrition. https://doi.org/10.1080/07315724.2004.10719406  Harrison FE, May JM. (2009). Vitamin C function in the brain: New evidence links ascorbate to neurotransmitter function. Brain Research Bulletin. https://doi.org/10.1016/j.brainresbull.2009.05.018  de Oliveira IJL, et al. (2015). Effects of oral vitamin C supplementation on anxiety in students. Nutrition Journal. https://doi.org/10.1186/1475-2891-14-36  Stough C, et al. (2011). The effects of 90-day administration of a high-dose B-complex vitamin on work stress. Human Psychopharmacology. https://doi.org/10.1002/hup.1190  Singh A, et al. (1991). Effect of acute stress on plasma zinc. Biological Trace Element Research. https://doi.org/10.1007/BF02990385  Hofmann SG, Asnaani A, Vonk IJJ, Sawyer AT, Fang A. (2018). The efficacy of cognitive behavioral therapy: A review of meta-analyses. Frontiers in Psychology. https://doi.org/10.3389/fpsyg.2012.00117  Shaw RJ, et al. (2019). Mindfulness-based stress reduction and CBT for HPA axis habituation. Psychoneuroendocrinology. https://doi.org/10.1016/j.psyneuen.2019.104420  Chen Y-R, Hung K-W, Tsai J-C, et al. (2014). Efficacy of EMDR for PTSD: A meta-analysis. PLoS ONE. https://doi.org/10.1371/journal.pone.0103676   Explore more support: Better Than Before Breast Cancer Life Coaching Membership: https://www.thebreastcancerrecoverycoach.com/lifecoaching  Creating a Life You Love in 168 Hours a Week: https://www.thebreastcancerrecoverycoach.com/168-hours-sp    Let's Connect! If this episode helped you breathe a little easier, please share it with a friend or leave a review. Every share helps spread this message of hope, healing, and whole-person wellness.

SpaceTime with Stuart Gary | Astronomy, Space & Science News
The Comet That Cooled the Earth - Unpacking the Younger Dryas Mystery

SpaceTime with Stuart Gary | Astronomy, Space & Science News

Play Episode Listen Later Aug 22, 2025 19:58


In this episode of SpaceTime, we delve into intriguing new research that challenges our understanding of Earth's climatic history, the discovery of a rare astronomical phenomenon, and China's advancements in lunar exploration.Did a Comet Trigger the Younger Dryas Cool Off?A groundbreaking study has emerged suggesting that a massive comet may have instigated Earth's Younger Dryas cool off event, traditionally attributed to glacial meltwater. Analysis of ocean sediments published in the journal PLOS One reveals geochemical clues that support the hypothesis of Earth encountering a disintegrating comet around 12,800 years ago. This event could have led to rapid cooling, with temperatures plummeting by approximately 10 degrees Celsius within a year. The findings indicate a potential link between comet dust and significant climate shifts, inviting further investigation into this captivating theory.Discovery of a Rare White Dwarf Merger RemnantAstronomers have identified an ultra-massive white dwarf star resulting from the merger of two stars, rather than the evolution of a single star. This discovery, made possible by NASA's Hubble Space Telescope, suggests that such white dwarf mergers may be more common than previously thought. The object, catalogued as WD0525 526, is located 126 light years away and is about 20% more massive than our Sun. Hubble's ultraviolet observations revealed carbon in its atmosphere, a sign of its violent origin, challenging previous assumptions about white dwarf formation.China Tests Its New Manned Lunar LanderIn a significant milestone for lunar exploration, China has successfully conducted a test flight of its new manned lunar landing craft, named Lanyu. This test, which included a controlled landing and takeoff, marks a crucial step in China's ambitions to send taikonauts to the Moon by 2030. The Lanyu is designed to carry astronauts from lunar orbit to the surface and back, with plans for a permanent lunar base in collaboration with Russia in the early 2030s.www.spacetimewithstuartgary.com✍️ Episode ReferencesPLOS Onehttps://journals.plos.org/plosone/Nature Astronomyhttps://www.nature.com/natureastronomy/NASA Hubble Space Telescopehttps://www.nasa.gov/mission_pages/hubble/main/index.htmlBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-space-astronomy--2458531/support.

Loving Life- A Guide to a Positive Mindset
123. Reclaim Your Focus: A Mindful Digital Detox for a Stronger Mindset

Loving Life- A Guide to a Positive Mindset

Play Episode Listen Later Aug 22, 2025 25:13


Let me know what you loved about the episode!Do you ever feel like your mind is constantly cluttered with notifications, endless scrolling, and the pressure to always be ‘on'? In this episode, I share how taking a mindful digital detox can help you (and me!) reclaim your focus, reduce stress, and improve your mental clarity.We dive into why screens are so addictive, the impact of digital distractions on your brain and creativity, and how constant device use can even disrupt your sleep by affecting melatonin production. I also guide you through a gentle visualisation to help you reconnect with the present moment, boost creativity, and feel calmer in your daily life.By the end of this episode, you'll have practical tips to start your own digital detox, improve your well-being, and create space for focus, creativity, and presence in your life.What you'll get from this episode:Why taking breaks from screens is essential for mental clarity and focus.How excessive screen time affects your brain, memory, and decision-making (Loh & Kanai, 2014, PLoS ONE).The science behind screen addiction and why notifications trigger dopamine hits.How blue light impacts melatonin production and your sleep quality.Ways a digital detox can boost creativity, reduce stress, and enhance overall well-being.Practical tips to set boundaries with technology and create unplugged time.A guided visualisation to reconnect with the present moment and calm your mind.Try This Today:I challenge you to join me in a 24-hour digital detox. Come on over to my Facebook group and let me know how you feel about this!✨ Doors are now open for Magnetic Manifestation, my 6-week live experience to help you clear subconscious blocks, align your energy, and become magnetic to your desires.We start mid-September, with lifetime access to this round's replays included. Find all the details and join us here https://magneticmanifestation.lisadavidge.co.uk/magneticmanifestationSupport the showLinks + Resources:

Wissensnachrichten - Deutschlandfunk Nova
Musik, Gewicht, Spracherkennung

Wissensnachrichten - Deutschlandfunk Nova

Play Episode Listen Later Aug 21, 2025 5:17


Die Themen in den Wissensnachrichten: +++ Unterschiedliche Musik weckt unterschiedliche Erinnerungen +++ Gene beeinflussen Gewicht auch ohne Vererbung +++ Auch KI versteht Dialekte schlecht +++**********Weiterführende Quellen zu dieser Folge:Qualities of music-evoked autobiographical memories are associated with auditory features of the memory-evoking music/ Plos One, 20.08.2025The association between parental BMI and offspring adiposity: A genetically informed analysis of trios/ Plos Genetics, 05.08.2025A Multi-Dialectal Dataset for German Dialect ASR and Dialect-to-Standard Speech Translation/ Interspeech, 17. bis 21.08.2025Scalable metasurface-enhanced supercool cement/ Science Advances, 20.08.2025VIVIT: Resolving trans-scale volumetric biological architectures via ionic glassy tissue/ Cell, 11.08.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Marathon Running Podcast by We Got the Runs
274. Marathon Taper - A Masterclass

Marathon Running Podcast by We Got the Runs

Play Episode Listen Later Aug 18, 2025 29:35


This week on The Marathon Running Podcast, we tackle the most misunderstood phase of marathon training: the taper. Host [Insert Host Name Here] compares this final stage to the difference between cramming and consolidating for a major exam, sharing a personal story about how his own failed taper taught him the hard way that less is truly more. For solo runners like Letty, mastering the taper is especially crucial, as it's the final step to ensure your body is primed for an independent race. We dive into the science of supercompensation, explaining how resting unlocks your full physiological potential by rebuilding muscle, replenishing glycogen, and boosting your immune system.Whether you're battling the "taper crazies" or feeling anxious about the reduced mileage, this episode is a deep dive into the practical blueprint and mental strategies you need to arrive at the starting line feeling strong, confident, and ready for your best race. Trust the process, because the taper isn't about losing fitness—it's about unlocking it for that final, glorious solo effort.Here are our research citations:

The Dr. Jud Podcast
Mindfulness and meditation - Beyond the Big Five: A New Approach to Understanding Personality

The Dr. Jud Podcast

Play Episode Listen Later Aug 9, 2025 10:42


Development and Validation of the Behavioral Tendencies QuestionnaireIn this episode, Dr. Jud Brewer and Dr. Nicholas Van Dam discuss the creation of the Behavioral Tendencies Questionnaire (BTQ), a novel tool for assessing personality traits based on behavioral approach, avoidance, and equivocation. Rooted in both contemporary psychology and ancient Buddhist typologies, the BTQ categorizes individuals into three primary temperaments: Greedy/Faithful (approach-oriented), Aversive/Discerning (avoidance-oriented), and Deluded/Speculative (equivocation-oriented). This study validated the BTQ using modern psychometric techniques, demonstrating its utility for personality research and mindfulness-based interventions. Tune in to learn how these behavioral tendencies shape our interactions, decision-making, and well-being.Full Reference:Van Dam, N. T., Brown, A., Mole, T. B., Davis, J. H., Britton, W. B., & Brewer, J. A. (2015). Development and Validation of the Behavioral Tendencies Questionnaire. PLoS ONE, 10(11), e0140867. https://doi.org/10.1371/journal.pone.0140867Let's connect on Instagram

Wilde Eeuwen
Aflevering 2: Waarom Doi zijn oudoom moet opeten

Wilde Eeuwen

Play Episode Listen Later Aug 8, 2025 42:37


Het is 40.000 jaar geleden. De jonge Doi staat oog in oog met zijn verre familie, een groep dansende neanderthalers. Zullen ze hem accepteren? Wilde Eeuwen, het begin. Iedere vrijdag een nieuwe aflevering. Meer informatie: nrc.nl/wilde-eeuwenHeeft u vragen, suggesties of ideeën over onze journalistiek? Mail dan naar onze ombudsman via ombudsman@nrc.nl.Tekst en presentatie: Hendrik SpieringRedactie en regie: Mirjam van ZuidamMuziek, montage en mixage: Rufus van BaardwijkBeeld: Jeen BertingVormgeving: Yannick MortierVoor deze aflevering is onder meer gebruikt gemaakt van deze literatuur: Francesca Romagnoli e.a. (eds) 'Updating Neanderthals. Understanding Behavioural Complexity in the Late Middle Palaeolithic', Academic Press 2022 Mateja Hajdinjak e.a ‘Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry' in Nature 8 april 2021. Rebecca Wragg Sykes. 'Kindred. Neanderthal Life, Love, Death and Art', Bloomsbury 2021 Rudolf Botha. 'Neanderthal Language. Demystifying the Linguistic Powers of our Extinct Cousins', Cambridge University Press 2020 Katerina Harvati. 'Paleoanthropology of the Balkans and Anatolia. Human Evolution and its Context', Springer Press 2016 Qiaomei Fu e.a. ‘An early modern human from Romania with a recent Neanderthal ancestor' in Nature, 13 augustus 2015. Wil Roebroeks en Paola Villa ‘Neandertal Demise: An Archaeological Analysis of the Modern Human Superiority Complex' in PLOS One, 30 april 2014. João Zilhão e.a. ‘The Peştera cu Oase People. Europe's Earliest Modern Humans' in K. Boyle e.d. (eds) Rethinking the Human Revolution, McDonald Institute for Archaeological Research, 2007.Zie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

Wissensnachrichten - Deutschlandfunk Nova
KI-Ratschläge, Kakadu-Dancemoves, Kakao

Wissensnachrichten - Deutschlandfunk Nova

Play Episode Listen Later Aug 7, 2025 5:46


CN: In einer Meldung werden die Themen Selbstverletzung und Suizid behandelt.**********Die Themen in den Wissensnachrichten: +++ ChatGPT liefert Tipps zu Drogennehmen, Selbstverletzung und mehr +++ Viele Kakadu-Arten haben Tanzmoves drauf +++ Wie Kakao-Plantagen klimafreundlicher werden können +++**********Weiterführende Quellen zu dieser Folge:Fake Friend. How ChatGPT betrays vulnerable teens by encouraging dangerous behavior, Center for Countering Digital Hate, 06.08.2025Dance behaviour in cockatoos: Implications for cognitive processes and welfare, Plos One, 06.08.2025Beyond victimhood and perpetration: Reconstruction of the ingroup's historical role in eight Eastern and Western European countries under Nazi occupation, Political Psychology, 25.09.2024The unrealized potential of agroforestry for an emissions-intensive agricultural commodity, Nature Sustainability, 06.08.2025Fatigue in long-term cancer survivors: prevalence, associated factors, and mortality. A prospective population-based study. British Journal of Cancer, 15.07.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Sigma Nutrition Radio
#572: Can You Trust Industry-Funded Nutrition Studies? Here's How to Tell

Sigma Nutrition Radio

Play Episode Listen Later Aug 5, 2025 69:40


Nutrition science plays a pivotal role in shaping public health advice, but the influence of industry funding on research has become a pressing concern. In this episode we want to examine whether we can trust nutrition studies funded by food and beverage companies, and how you can discern study credibility.  The discussion is highly relevant in today's landscape, where conflicts of interest and bias in research are under scrutiny amidst debates on sugar, processed foods, and diet recommendations. By exploring how industry sponsorship might skew results or interpretations, this episode speaks to broader issues of scientific trustworthiness and evidence-based policy in nutrition and public health.  In this episode, we take a look at some recent publications that showed how study results and reporting differed significantly depending on if industry had funded the study or not. We delve into how this happens. As most often it is not a case of data fabrication or corruption, but rather how bias leads to studies being designed and reported differently. We walk through some examples, as well as highlighting some industry-funded studies that didn't provide a “pro-industry” result and conclusion. The hope is that the episode allows you to understand why this is a problem, how to spot it, and how to know if you can trust the results of an industry-funded study. Timestamps [00:36] Alan's upcoming study [04:47] Discussion on industry funding in nutrition research [15:06] Case study: industry influence on red meat research [30:43] Case study: artificial sweeteners and industry influence [36:37] Case study: sugar industry's role in research [38:06] Critical appraisal of industry-funded studies [51:58] Case study: when industry-funded study results can be trusted [01:01:51] Guidelines for assessing research quality [01:07:14] Key ideas segment (premium-only) Related Resources Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Join Alan's Alinea Nutrition Research Hub Enroll in the next cohort of our Applied Nutrition Literacy course Recommended episode: #472: Compared To What? – Understanding Food Substitution Analysis & Adjustment Models Studies mentioned: López-Moreno et al., Am J Clin Nutr. 2025 Jun;121(6):1246-1257 Tobias, 2025 – You are what you don't eat Mandrioli D, Kearns CE, Bero LA (2016) PLOS ONE 15(3): e0230469 Schillinger et al., Ann Intern Med. 2016 Nov 1;165(12):895–897 Schmidt et al., 2021 – The impact of diets rich in low-fat or full-fat dairy on glucose tolerance and its determinants: a randomized controlled trial Schmidt et al., 2021 – Impact of low-fat and full-fat dairy foods on fasting lipid profile and blood pressure: exploratory endpoints of a randomized controlled trial

The Studies Show
Episode 81: Retraction

The Studies Show

Play Episode Listen Later Aug 5, 2025 71:53


RETRACTED // In this episode of The Studies Show, Tom and Stuart discuss retraction, the process of removing articles from the scientific record. How often is it due to fraud? How many papers get retracted—and is the number increasing? Is it good or bad for a scientist to retract an article? // RETRACTEDWant even more podcasts? Now our sponsor, Works in Progress magazine, has a podcast where their editors talk to people with interesting progress-related ideas. One such person is the historian Anton Howes, who is interviewed about the unexpected origins of the Industrial Revolution in the latest episode. Find it at worksinprogress.news.Show notes* Retraction Watch, the extremely useful website that tracks and investigates retractions* Science's writeup of the long process of retracting the GFAJ-1 “arsenic bacteria” paper* Original paper; retraction note; response from the authors* The first known retraction, from 1755* Retraction Watch's discussion of it* Adam Marcus and Ivan Oransky on tracking retractions over time* 2022 PLOS ONE article on the number of retractions over time* Scholarly Kitchen post on the rate of retractions over time* Nature article on the 10,000 retractions in 2023 alone* 2011 article on the causes of retractions* 2012 article on the same: misconduct is found to account for the biggest proportion* James Heathers on the disastrous story of Wiley buying Hindawi* The retraction guidelines from COPE* The paper with a diagram of a very well-endowed rat* Are authors punished for retractions? Not necessarily* Reputational advantage from correcting errors* 2022 article on how scientists still regularly cite retracted papers (without knowing they're retracted)CreditsWe're very grateful to Ivan Oransky from Retraction Watch for his help with this episode. Any mistakes are ours. The Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe

Pure Animal Podcast
Rethinking healthy ageing in dogs with Dr Matthew Muir

Pure Animal Podcast

Play Episode Listen Later Aug 5, 2025 54:06


In this episode Dr Sarah Howard discusses healthy ageing in dogs with Dr Matthew Muir. Topics discussed include: The reason ageing is currently a hot topic. What leads to an increased lifespan and better quality of life? Diet changes that can impact ageing in dogs. Dr Muir discusses what we should avoid in order to increase lifespan. Matthew goes into details of what dogs' diets should look like to prevent disease. How often should we be feeding our pets? What happens to the gut microbiome as dogs get older? Dr Muir delves into supplements that can be beneficial for ageing and emerging tools that are becoming available. The importance of preventative medicine - proactive vs reactive care. Accelerators of biological ageing. Additional resources: https://pubmed.ncbi.nlm.nih.gov/11991408/ https://pmc.ncbi.nlm.nih.gov/articles/PMC11675035/https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1355560/full https://pmc.ncbi.nlm.nih.gov/articles/PMC11505706/ https://www.mdpi.com/1660-3397/18/11/564https://pmc.ncbi.nlm.nih.gov/articles/PMC4936929/ https://pubmed.ncbi.nlm.nih.gov/22216092/ Adams VJ, Watson P, Carmichael S, Gerry S, Penell J, Morgan DM. Exceptional longevity and potential determinants of successful ageing in a cohort of 39 Labrador retrievers: results of a prospective longitudinal study. Acta Vet Scand. 2016;58:29. doi:10.1186/s13028-016-0204-8 Cupp CJ, Jean-Philippe C, Kerr WW, Patil AR. Effect of nutritional interventions on longevity of senior cats. Int J Appl Res Vet Med. 2007;5(3):133–149 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Jackson J, Radford AD, Belshaw Z, Wallis LJ, Kubinyi E, German AJ, Westgarth C. Using veterinary health records at scale to investigate ageing dogs and their common issues in primary care. J Small Anim Pract. 2025;66(2):81–91. doi:10.1111/jsap.13809 Creevy KE, O'Neill DG, Promislow DEL. Morbidity and mortality in elderly dogs – a model for human aging. BMC Vet Res. 2022;18(1):456. doi:10.1186/s12917-022-03518-8 Lewis TW, Wiles BM, Llewellyn-Zaidi AM, Evans KM, O’Neill DG. Longevity and mortality in Kennel Club registered dog breeds in the UK in 2014. Canine Genet Epidemiol. 2018;5:10. doi:10.1186/s40575-018-0066-8 Kealy RD, Lawler DF, Ballam JM, Mantz SL, Biery DN, Greeley EH, Lust G, Segre M, Smith GK, Stowe HD. Effects of diet restriction on life span and age-related changes in dogs. J Am Vet Med Assoc. 2002;220(9):1315–1320. doi:10.2460/javma.2002.220.1315 Guelfi G, Capaccia C, Tedeschi M, Bufalari A, Leonardi L, Cenci-Goga B, Maranesi M. Dog aging: a comprehensive review of molecular, cellular, and physiological processes. Cells. 2024;13(24):2101. doi:10.3390/cells13242101 Laflamme DP. Nutritional care for aging cats and dogs. Vet Clin North Am Small Anim Pract. 2012;42(4):769–791. doi:10.1016/j.cvsm.2012.04.002 Hall JA, Jewell DE. Feeding healthy beagles medium-chain triglycerides, fish oil, and L-carnitine offsets age-related changes in serum fatty acids and carnitine metabolites. PLoS One. 2012;7(11):e49510. doi:10.1371/journal.pone.0049510 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Bray EE, Zheng Z, Tolbert MK, McCoy BM, Kaeberlein M, Kerr KF; Dog Aging Project Consortium. Once-daily feeding is associated with better health in companion dogs: results from the Dog Aging Project. GeroScience. 2022;44(3):1779–1790. doi:10.1007/s11357-022-00575-7 Palaseweenun P, Hagen‐Plantinga EA, Schonewille JT, Koop G, Butre C, Jonathan M, Wierenga PA, Hendriks WH. Urinary excretion of advanced glycation end products in dogs and cats. J Anim Physiol Anim Nutr (Berl). 2021;105(1):149–156. doi:10.1111/jpn.13347 Yang L, Yang L, Cai Y, Luo Y, Wang H, Wang L, Chen J, Liu X, Wu Y, Qin Y, Wu Z, Liu N. Natural mycotoxin contamination in dog food: a review on toxicity and detoxification methods. Ecotoxicol Environ Saf. 2023;257:114948. doi:10.1016/j.ecoenv.2023.114948 Bridglalsingh S, Archer-Hartmann S, Azadi P, Barbier de La Serre C, Remillard RL, Sunvold GD, Bartges JW. Association of four differently processed diets with plasma and urine advanced glycation end products and serum soluble receptor for advanced glycation end products concentration in healthy dogs. J Anim Physiol Anim Nutr (Berl). 2024;108(3):735–751. doi:10.1111/jpn.13927 Marchi PH, Vendramini THA, Perini MP, Zafalon RVA, Amaral AR, Ochamotto VA, Da Silveira JC, Dagli MLZ, Brunetto MA. Obesity, inflammation, and cancer in dogs: review and perspectives. Front Vet Sci. 2022;9:1004122. doi:10.3389/fvets.2022.1004122 Schmid SM, Hoffman JM, Prescott J, Ernst H, Promislow DEL, Creevy KE; Dog Aging Project Consortium. The companion dog as a model for inflammaging: a cross-sectional pilot study. GeroScience. 2024;46(6):5395–5407. doi:10.1007/s11357-024-01217-w Ren J, Li H, Zeng G, Pang B, Wang Q, Wei J. Gut microbiome-mediated mechanisms in aging-related diseases: are probiotics ready for prime time? Front Pharmacol. 2023;14:1178596. doi:10.3389/fphar.2023.1178596 Parker A, Romano S, Ansorge R, Aboelnour A, Le Gall G, Savva GM, Pontifex MG, Telatin A, Baker D, Jones E, Vauzour D, Rudder S, Blackshaw LA, Jeffery G, Carding SR. Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain. Microbiome. 2022;10:68. doi:10.1186/s40168-022-01262-3 Ulluwishewa D, Anderson RC, McNabb WC, et al. Regulation of tight junction permeability by intestinal bacteria and dietary components. J Nutr. 2011;141(5):769–76. doi:10.3945/jn.110.135657 Cao L, Lee SG, Lim KT, Kim HR. Potential anti-aging substances derived from seaweeds. Mar Drugs. 2020;18(11):564. doi:10.3390/md18110564 Grzeczka A, Graczyk S, Kordowitzki P. Pleiotropic effects of resveratrol on aging-related cardiovascular diseases—what can we learn from research in dogs? Cells. 2024;13(20):1732. doi:10.3390/cells13201732 Kusaba A, Arai T. Shiitake mushroom powder supplementation increases antioxidative activity in dogs. Front Vet Sci. 2024;11:1355560. doi:10.3389/fvets.2024.1355560 Cho HW, Choi S, Seo K, Kim KH, Jeon JH, Kim CH, Lim S, Jeong S, Chun JL. Gut microbiota profiling in aged dogs after feeding pet food contained Hericium erinaceus. J Anim Sci Technol. 2022 Sep;64(5):937-949. Kaur J, Seshadri S, Golla KH, Sampara P. Efficacy and safety of standardized ashwagandha (Withania somnifera) root extract on reducing stress and anxiety in domestic dogs: A randomized controlled trial. J Vet Behav. 2022;51:8–15. Bharani KK, Devarasetti AK, Carey L, Khurana A, Kollipaka R, Hanuman DDV, Chetla VS, Banothu AK. Effects of ashwagandha (Withania somnifera) root extract on aging-related changes in healthy geriatric dogs: A randomized, double-blinded placebo-controlled study. Vet Med Sci. 2024 Sep;10(5):e1556 Sacoor C, Marugg JD, Lima NR, Empadinhas N, Montezinho L. Gut-brain axis impact on canine anxiety disorders: new challenges for behavioral veterinary medicine. Vet Med Int. 2024;2024:2856759. doi:10.1155/2024/2856759 Lee E, Carreras-Gallo N, Lopez L, Turner L, Lin A, Mendez TL, Went H, Tomusiak A, Verdin E, Corley M, Ndhlovu L, Smith R, Dwaraka VB. Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions. Aging (Albany NY). 2024;16(4):3088–3106. doi:10.18632/aging.205581 Bitto A, Ito TK, Pineda VV, LeTexier NJ, Huang HZ, Sutlief E, Tung H, Vizzini N, Chen B, Smith K, Meza D, Yajima M, Beyer RP, Kerr KF, Davis DJ, Gillespie CH, Snyder JM, Treuting PM, Kaeberlein M. Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice. eLife. 2016;5:e16351. doi:10.7554/eLife.16351 Urfer SR, Kaeberlein TL, Mailheau S, Bergman PJ, Creevy KE, Promislow DEL, Kaeberlein M. A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs. GeroScience. 2017;39(2):117–127. doi:10.1007/s11357-017-9972-z Kaeberlein M, Creevy KE, Promislow DEL. The Dog Aging Project: translational geroscience in companion animals. Mamm Genome. 2016;27(7–8):279–288. doi:10.1007/s00335-016-9638- Mulder IE, Schmidt B, Lewis M, Delday M, Stokes CR, Bailey M, Aminov RI, Gill BP, Pluske JR, Mayer CD, Kelly D. Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity. PLoS One. 2011;6(12):e28279. doi:10.1371/journal.pone.0028279 Hemida M, Vuori KA, Moore R, Anturaniemi J, Hielm-Björkman A. Early life modifiable exposures and their association with owner-reported inflammatory bowel disease symptoms in adult dogs. Front Vet Sci. 2021;8:552350. doi:10.3389/fvets.2021.552350 McMahon JE, Graves JL, Tovar AP, Peloquin M, Greenwood K, Chen FL, Nelson M, McCandless EE, Halioua-Haubold CL, Juarez-Salinas D. Translational immune and metabolic markers of aging in dogs. Sci Rep. 2025;15:14460. doi:10.1038/s41598-025-51976-3 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Santos JDP, Cunha E, Nunes T, Tavares L, Oliveira M. Relation between periodontal disease and systemic diseases in dogs. Res Vet Sci. 2019;125:136–140. doi:10.1016/j.rvsc.2019.05.011 Selting KA, Ringold R, Husbands B, Pithua PO. Thymidine kinase type 1 and C-reactive protein concentrations in dogs with spontaneously occurring cancer. J Vet Intern Med. 2016;30(4):1159–1166. doi:10.1111/jvim.13954 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Clark JD, Rager DR, Crowell-Davis S, Evans DL. Housing and exercise of dogs: effects on behaviour, immune function and cortisol concentration. Lab Anim Sci. 1997;47(5):500–510 See omnystudio.com/listener for privacy information.

The KickASK Podcast
TDC 059: Live Wild or Die Boring (Part 1)

The KickASK Podcast

Play Episode Listen Later Aug 2, 2025 12:57 Transcription Available


TDC 059: Live Wild or Die Boring: The Urgent Case for Reconnecting with the Natural World (Part 1)Why nature isn't just good for your soul—it's essential for survival, creativity, and breakthrough innovation.Episode SummaryIn this episode of The Digital Contrarian, host Ryan Levesque shares insights from recording his upcoming book Return to Real and reveals shocking research about our digital lifestyle.You'll discover how concrete environments increase early death by 12%, learn why nature walks boost creativity by 60%, and understand why tech founders won't use their own products.Question of the Day

Biologia em Meia Hora

Será que pombos podem aprender a diferenciar imagens médicas? Separe trinta minutinhos do seu dia e descubra, com Mila Massuda, como pombos foram treinados e diferenciar imagens com e sem tumores e o que podemos aprender sobre isso.Apresentação: Mila Massuda (@milamassuda)Roteiro: Mila Massuda (@milamassuda) e Emilio Garcia (@emilioblablalogia)Revisão de Roteiro: Vee Almeida e Caio de Santis (@caiodesantis)Técnico de Gravação: Julianna Harsche (@juvisharsche)Editora: Lilian Correa (@_lilianleme)Mixagem e Masterização: Bruno Midões (@bruno_midoes) Produção: Prof. Vítor Soares (@profvitorsoares), Matheus Herédia (@Matheus_Heredia), BláBláLogia (@blablalogia), Caio de Santis (@caiodesantis) e Biologia em Meia Hora (@biologiaemmeiahora)Gravado e editado nos estúdios TocaCast, do grupo Tocalivros (@tocalivros)REFERÊNCIASLEVENSON, R. M. et al. Pigeons (Columba livia) as Trainable Observers of Pathology and Radiology Breast Cancer Images. PLOS ONE, v. 10, n. 11, p. e0141357, 18 nov. 2015.

Wissensnachrichten - Deutschlandfunk Nova
Tiefseetiere, Kuschelhormon, Mikroplastik

Wissensnachrichten - Deutschlandfunk Nova

Play Episode Listen Later Jul 31, 2025 5:39


Die Themen in den Wissensnachrichten +++ Spezialboot findet ganze Ökosysteme in der Tiefsee +++ Am meisten "Kuschelhormone" gibt es erst nach dem Sex +++ Drinnen atmen wir viel Mikroplastik ein +++**********Weiterführende Quellen zu dieser Folge:Flourishing chemosynthetic life at the greatest depths of hadal trenches. Nature, 30.07.2025Charting Salivary Oxytocin Across an Episode of Naturally Occurring Partnered Sex. Archives of Sex Behaviour, 02.05.2025Human exposure to PM10 microplastics in indoor air. Plos One, 30.07.2025Outburst of a subglacial flood from the surface of the Greenland Ice Sheet. Nature Geoscience, 30.07.2025How sustainable was ancient Roman concrete? iScience, 30.07.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Against The Grain - The Podcast
ATGthePodcast 286 - A Conversation with Damien Pattinson, Executive Director, eLife Sciences Publications, Ltd.

Against The Grain - The Podcast

Play Episode Listen Later Jul 30, 2025 51:42


Today's episode features guest host Michael Upshall (guest editor, Charleston Briefings) who talks with Damien Pattinson, Executive Director, eLife Sciences Publications, Ltd. Damien earned his PhD in neuroscience. After a postdoc at Kings College, London, UK, he began his career in scholarly publishing almost twenty years ago, first joining BMJ as a scientific editor, then PLOS ONE as executive director and then as editorial director, and Research Square as VP of Publishing Innovation.  Damien joined eLife in 2020. In this conversation, he talks about Open Science and the eLife publishing model.  LinkedIn: https://www.linkedin.com/in/mupshall/ https://www.linkedin.com/in/damian-pattinson-b054508/ Twitter: Keywords:  #eLife #OpenScience #OpenResearch #Research #FutureOfResearch #ResearchIntegrity #AcademicResearch #OpenAccess #OpenSource #PeerReview #HigherEducation #LibraryInnovation #Innovation #LibraryJobs #career #collaboration #scholcomm #ScholarlyCommunication #libraries #librarianship #LibraryNeeds #LibraryLove #ScholarlyPublishing #AcademicPublishing #publishing #LibrariesAndPublishers #podcasts

The Studies Show
Episode 80: Mindfulness meditation

The Studies Show

Play Episode Listen Later Jul 29, 2025 64:59


Pay attention. Focus on your breathing. Live in the moment. Accept yourself. Do you have a self? Focus on that self. And so on. This is, of course, the practice of mindfulness meditation, which seems to be everywhere: in schools, at work, in apps, and all over the scientific literature.Do any of the claimed effects of mindfulness meditation (relieving your depression! Changing the structure of your brain!) actually add up? In this episode of The Studies Show, Tom and Stuart focus calmly, serenely, and gratefully on their own thoughts, and then find out.The Studies Show is brought to you by Works in Progress magazine. WiP has started doing its own podcasts! Don't worry—we give you permission to listen to them. The one we mentioned on the show this week is an interview with Stian Westlake, the extremely interesting Chief Executive of the UK's Economic and Social Research Council and expert in the “intangible” economy.Show notes* When Sam Harris tried to get Richard Dawkins to meditate on a podcast* Tom's 2014 article on mindfulness, before all the criticisms started appearing* Mindfulness tips from the NHS* The 2017 critical paper from Perspectives on Psychological Science* 2014 meta-analysis finding no effect beyond active controls* 2021 meta-analysis drawing a similar conclusion* The now-retracted 2023 Scientific Reports meta-analysis on mindfulness and brain structure* Eiko Fried's article discussing his experience critiquing the paper* The eventual retraction note* PLOS ONE paper from 2016 on the number of positive results found in mindfulness trials* 2015 meta-analysis on mindfulness in healthcare* The eventual retraction note* 2022 writeup of the MYRIAD study of school-based mindfulness techniques* Critical opinion piece by a mindfulness sceptic* Study on mindfulness in the context of neoliberal capitalismCreditsThe Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe

Wissensnachrichten - Deutschlandfunk Nova
Online-Dating, KI-Musik, Optimismus

Wissensnachrichten - Deutschlandfunk Nova

Play Episode Listen Later Jul 25, 2025 5:44


Die Themen in den Wissensnachrichten: +++ Tschechische Studie: Wie Männer und Frauen beim Online-Dating ticken +++ KI-Musik wird im Gehirn möglicherweise anders verarbeitet +++ Optimisten denken ähnlich +++**********Weiterführende Quellen zu dieser Folge:It takes two to tango: A directed two-mode network approach to desirability on a mobile dating app/ PLOS One, 23.07.2025Emotional impact of AI-generated vs. human-composed music in audiovisual media: A biometric and self-report study/ PLOS One, 25.06.2025Optimistic people are all alike: Shared neural representations supporting episodic future thinking among optimistic individuals/ PNAS, 21.07.2025Safety and pharmacokinetics of the non-hormonal male contraceptive YCT-529/ Communications Medicine, 22.07.2025Studie zu Tourismus an der Nordsee: Einheimische mögen Besucher/ NDR, 25.07.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

The Studies Show
Episode 79: Cancer rates

The Studies Show

Play Episode Listen Later Jul 22, 2025 52:11


Are cancer rates going up or down? It seems like depending on where you look, you'll find different answers to the question. What's going on here — have some writers just got it completely wrong? Is it something to do with different types of cancer? Are we being confused by some kind of weird statistical artefact? All of the above? In this episode of The Studies Show, we do our very best to find out.The Studies Show is brought to you by Works in Progress magazine, the ultimate place online to read about new and underrated scientific and technological ideas that could make the world a better place. You can find a huge range of essays online, for free, at www.worksinprogress.co.Show notes* BBC Future article on early-onset cancer rates* BMJ Oncology article on global cancer incidence increasing by 79%* And its online supplementary information* July 2025 Economist article on how the world is winning the war on cancer* Saloni Dattani's 2025 article on the decline in global cancer rates* The GLOBOCAN data update from the IARC, 2002 and 2008* Our World in Data's graph on global cancer incidence over time* Their graph on smoking rates and lung cancer deaths* Their graph on stomach cancer death rates* New RCT on vaping and smoking cessation* A 90% drop in cervical cancer rates in England* The hepatitis B vaccine and a massive drop in liver cancer incidence in China* On H. pylorii, ulcers, and cancer* 2000 JAMA article questioning the utility of the 5-year survival rate statistic* 2014 PLOS ONE article that's more positive about the statistic* Tom's BuzzFeed News article on oncology* RCT of herceptin on breast cancer survival* Study on rates of colorectal cancer * And the same, in relation to BMICreditsThe Studies Show is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.thestudiesshowpod.com/subscribe

Scientificast
L'accelerazione del microbiota a scuola

Scientificast

Play Episode Listen Later Jul 21, 2025 61:13


Ai microfoni Kuna e Ilaria per la puntata 572. Apre le danze Kuna che, approfittando delle recenti polemiche sull'esame di stato, discute il concetto di scuola senza voto e le sperimentazioni intraprese in Italia e all'estero, da cui emerge come l'idea di limitare l'uso del giudizio numerico alla valutazione finale, se accompagnata da una didattica adeguata, possa migliorare il clima e i risultati dell'apprendimento. Per approfondire:Cristiano Corsini, La fabbrica dei voti. Sull'utilità e il danno della valutazione a scuola, Editori Laterza (2025)Vincenzo Arte, Crescere senza voti, Mondadori, 2023Per la rubrica Scientifibook, Andrea e Giuliana propongono:L'EVOLUZIONISTA RILUTTANTEDavid Quammen – Raffaello Cortina Editore (272 pp, 22 euro)TEMPO DI RITORNOFerdinando Cotugno – Guanda (264 pp, 18 euro)STORIE STRAORDINARIE DI OGGETTI ORDINARIEmily Prokop – Apogeo (215 pp, 22 euro)SONO PARTE DELL'INFINITOKieran Fox – Egea editore (308 p, 26,90 euro)ENRICO FERMI. IL GENIO ATOMICOAndrea Pau – Gallucci (256 pp, 14,90 euro)Dopo una barza PESANTE, Ilaria ci parla di due studi affascinanti che mostrano quanto sia stretta la connessione tra il nostro corpo e la salute. Il primo ci porta nelle profondità del microbiota intestinale, dove i ricercatori hanno identificato un composto chiamato imidazolo propionato (ImP) che potrebbe funzionare sia come campanello d'allarme precoce, sia come causa diretta dell'aterosclerosi. Un piccolo metabolita con un grande impatto sul cuore!Mastrangelo, A., Robles-Vera, I., Mañanes, D. et al., Imidazole propionate is a driver and therapeutic target in atherosclerosis, Nature(2025), https://doi.org/10.1038/s41586-025-09263-wIl secondo studio, invece, ci riporta a terra – letteralmente – perché dimostra che basta camminare un po' più velocemente del solito, circa 14 passi in più al minuto, per migliorare significativamente la funzione fisica, soprattutto nelle persone anziane o a rischio di fragilità. Una buona notizia per chi cerca salute… a piccoli passi!Rubin, D.S., Hung, A., Yamamoto, E., Hedeker, D., Conroy, D.E., Huisingh-Scheetz, M., et al., Walking cadence as a measure of activity intensity and impact on functional capacity for prefrail and frail older adults, PLoS One 20(7): e0323759 (2025), https://doi.org/10.1371/journal.pone.0323759Diventa un supporter di questo podcast: https://www.spreaker.com/podcast/scientificast-la-scienza-come-non-l-hai-mai-sentita--1762253/support.

Iron Culture
Ep 336 - The Science Of Being Cool & Attractive

Iron Culture

Play Episode Listen Later Jul 16, 2025 66:19


In this episode of Iron Culture, Dr. Eric Trexler and Dr. Lauren Colenso-Semple discuss science related to attractiveness, coolness, and personality type. They explore scientific studies on the factors associated with perceived attractiveness and "coolness," discussing body fat percentages and societal perceptions. The conversation shifts to how personality traits appear to predict workout preferences and engagement in fitness, then they debate the importance of matching exercise to individual characteristics. Time stamps: 00:00 Introduction to Iron Culture and Guests 5:57 The Science of (Male) Attractiveness 10:39 Evolutionary Underpinnings of Male Attractiveness 13:53 Distorted Perceptions of Attractiveness (In the Fitness World) 20:10 The Irony of Pursuing Attractiveness 22:22 Body-Fat and Optimized Health 24:18 Surprising Article Feedback 28:50 Unrealistic Body Standards and Gender Perceptions 32:49 Achieving the Outcome Versus Doing Hard Things 35:07 Attractiveness is More Than Body Shape/Size 37:48 The Science of Being Cool 47:19 Matching Exercise To Personality Types References: Xia F, Sauciuvenaite J, Bissland R, Hambly C, Starr-Vaanholt L, Faries MD, et al. The relationship between body fatness and physical attractiveness in males. Personality and Individual Differences. 2025 Sep 1;243:113240. de Jager S, Coetzee N, Coetzee V. Facial Adiposity, Attractiveness, and Health: A Review. Front Psychol. 2018 Dec 21;9:2562. Brierley ME, Brooks KR, Mond J, Stevenson RJ, Stephen ID. The Body and the Beautiful: Health, Attractiveness and Body Composition in Men's and Women's Bodies. PLoS One. 2016;11(6):e0156722. Sorokowski P, Kościński K, Sorokowska A, Huanca T. Preference for Women's Body Mass and Waist-to-Hip Ratio in Tsimane' Men of the Bolivian Amazon: Biological and Cultural Determinants. PLoS One. 2014 Aug 22;9(8):e105468. Tovée MJ, Cornelissen PL. Female and male perceptions of female physical attractiveness in front-view and profile. Br J Psychol. 2001 May;92(Pt 2):391–402. Jayedi A, Khan TA, Aune D, Emadi A, Shab-Bidar S. Body fat and risk of all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies. Int J Obes (Lond). 2022 Sep;46(9):1573–81. Hu J, Chen X, Yang J, Giovannucci E, Lee DH, Luo W, et al. Association between fat mass and mortality: analysis of Mendelian randomization and lifestyle modification. Metabolism. 2022 Nov;136:155307. Ramlau-Hansen CH, Thulstrup AM, Nohr EA, Bonde JP, Sørensen TIA, Olsen J. Subfecundity in overweight and obese couples. Hum Reprod. 2007 Jun;22(6):1634–7. Wei S, Schmidt MD, Dwyer T, Norman RJ, Venn AJ. Obesity and menstrual irregularity: associations with SHBG, testosterone, and insulin. Obesity (Silver Spring). 2009 May;17(5):1070–6. Liu Y, Hu X, Xiong M, Li J, Jiang X, Wan Y, et al. Association of BMI with erectile dysfunction: A cross-sectional study of men from an andrology clinic. Front Endocrinol (Lausanne). 2023;14:1135024. https://psycnet.apa.org/doiLanding?doi=10.1037%2Fxge0001799 https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2025.1587472/full

Betreutes Fühlen
Negative Gedanken besiegen

Betreutes Fühlen

Play Episode Listen Later Jul 7, 2025 68:08


Was wäre wenn …? Hätte ich doch nur … Müsste ich nicht eigentlich…? Das kennt wahrscheinlich jeder von uns: Gedanken, die immer wieder um dieselben Themen kreisen. Man kommt nicht runter vom Gedankenkarussell. Wiederkehrende, belastende Gedanken sind ein zentrales Merkmal vieler psychischer Belastungen. In dieser Folge fragen sich Atze und Leon, warum wir dazu neigen, in solchen Denkschleifen zu verharren und werfen einen Blick auf aktuelle Forschungsansätze und evidenzbasierte Strategien zum Grübeln. Was ist normal und was ist schon nicht mehr gesund? Und was können wir konkret im Alltag tun, um das Gedankenkarussell zu stoppen? Fühlt euch gut betreut Leon & Atze Instagram: https://www.instagram.com/leonwindscheid/ https://www.instagram.com/atzeschroeder_offiziell/ Mehr zu unseren Werbepartnern findet ihr hier: https://linktr.ee/betreutesfuehlen Tickets: Atze: https://www.atzeschroeder.de/#termine Leon: https://leonwindscheid.de/tour/ VVK Münster 2025: https://betreutes-fuehlen.ticket.io/ Quellen: Review zu RNT & Transdiagnostik: Moulds, M. L., & McEvoy, P. M. (2025). Repetitive negative thinking as a transdiagnostic cognitive process. Nature Reviews Psychology, 1-15. https://www.nature.com/articles/s44159-024-00399-6 Übersichtsartikel über die Forschung von Susan Nolen-Hoeksema: Lyubomirsky, S., Layous, K., Chancellor, J., & Nelson, S. K. (2015). Thinking about rumination: The scholarly contributions and intellectual legacy of Susan Nolen-Hoeksema. Annual review of clinical psychology, 11(1), 1-22. https://www.annualreviews.org/content/journals/10.1146/annurev-clinpsy-032814-112733 Teismann, T., & Ehring, T. (2019). Pathologisches Grübeln (Vol. 74). Hogrefe Verlag GmbH & Company KG. Watkins, E. D., Moulds, M., & Mackintosh, B. (2005). Comparisons between rumination and worry in a non-clinical population. Behaviour research and therapy, 43(12), 1577-1585. Praktische Tipps: Wignall, N. (2020). 10 Simple Ways to Stop Overthinking Everything. https://nickwignall.com/overthinking/ Becker, E. S., & Margraf, J. (2008). Vor lauter Sorgen.... Hilfe für Betroffenen von Generalisierter Angststörung (GAS) und deren Angehörige. Weinheim: Beltz. Wahl, K., Ehring, T., Kley, H., Lieb, R., Meyer, A., Kordon, A., ... & Schönfeld, S. (2019). Is repetitive negative thinking a transdiagnostic process? A comparison of key processes of RNT in depression, generalized anxiety disorder, obsessive-compulsive disorder, and community controls. Journal of behavior therapy and experimental psychiatry, 64, 45-53. Querstret, D., & Cropley, M. (2013). Assessing treatments used to reduce rumination and/or worry: A systematic review. Clinical psychology review, 33(8), 996-1009. Wang, S., Lu, M., Dong, X., & Xu, Y. (2025). Does physical activity-based intervention decrease repetitive negative thinking? A systematic review. PLoS One, 20(4), e0319806. Repetitive Negative Thinking transdiag. zu betrachten, ist als Idee nichtneu: 2 Reviews kommen auch schon zu diesem Schluss: Ehring, T., & Watkins, E. R. (2008). Repetitive negative thinking as a transdiagnostic process. International journal of cognitive therapy, 1(3), 192-205. Harvey, A. G., Watkins, E., Mansell, W., & Shafran, R. (2004). Cognitive behavioural processes across psychological disorders. Oxford, UK: Oxford University Press Die Geschichte der Reagans: https://www.spiegel.de/geschichte/attentat-auf-ronald-reagan-a-947145.html https://www.latimes.com/local/obituaries/la-me-joan-quigley-20141024-story.html https://www.nytimes.com/2014/10/25/us/joan-quigley-astrologer-to-a-first-lady-is-dead-at-87.html Redaktion: Andy Hartard Produktion: Murmel Productions

Always On EM - Mayo Clinic Emergency Medicine
Chapter 45 - Airway to Heaven: A Primer on Mechanical Ventilation for Emergency Providers

Always On EM - Mayo Clinic Emergency Medicine

Play Episode Listen Later Jul 5, 2025 73:24


Dr. Harish Kinni, a triple-board-certified emergency medicine and critical care physician and assistant professor at the Mayo Clinic, provides an overview of the fundamentals of ventilator care for emergency department professionals. We will review key modes that we should know, the variables to set, how to adjust them for your patient's needs, and provide troubleshooting tips and tricks for when things suddenly go awry. This is sure to be one of the most helpful chapters of Always on EM, but don't let it take your breath away! CONTACTS X - @AlwaysOnEM; @VenkBellamkonda YouTube - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch Email - AlwaysOnEM@gmail.com REFERENCES & LINKS Swart P, Nijbroek SGLH, Paulus F, Neto AS, Schultz MJ. Sex Differences in Use of Low Tidal Volume Ventilation in COVID-19-Insights From the PRoVENT-COVID Study. Front Med (Lausanne). 2022 Jan 3;8:780005. doi: 10.3389/fmed.2021.780005. PMID: 35300177; PMCID: PMC8923734. McNicholas BA, Madotto F, Pham T, Rezoagli E, Masterson CH, Horie S, Bellani G, Brochard L, Laffey JG; LUNG SAFE Investigators and the ESICM Trials Group. Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study. Eur Respir J. 2019 Oct 17;54(4):1900609. doi: 10.1183/13993003.00609-2019. PMID: 31346004. Swart P, Deliberato RO, Johnson AEW, Pollard TJ, Bulgarelli L, Pelosi P, de Abreu MG, Schultz MJ, Neto AS. Impact of sex on use of low tidal volume ventilation in invasively ventilated ICU patients-A mediation analysis using two observational cohorts. PLoS One. 2021 Jul 14;16(7):e0253933. doi: 10.1371/journal.pone.0253933. PMID: 34260619; PMCID: PMC8279424. Evans, Laura1; Rhodes, Andrew2; Alhazzani, Waleed3; Antonelli, Massimo4; Coopersmith, Craig M.5; French, Craig6; Machado, Flávia R.7; Mcintyre, Lauralyn8; Ostermann, Marlies9; Prescott, Hallie C.10; Schorr, Christa11; Simpson, Steven12; Wiersinga, W. Joost13; Alshamsi, Fayez14; Angus, Derek C.15; Arabi, Yaseen16; Azevedo, Luciano17; Beale, Richard18; Beilman, Gregory19; Belley-Cote, Emilie20; Burry, Lisa21; Cecconi, Maurizio22; Centofanti, John23; Coz Yataco, Angel24; De Waele, Jan25; Dellinger, R. Phillip26; Doi, Kent27; Du, Bin28; Estenssoro, Elisa29; Ferrer, Ricard30; Gomersall, Charles31; Hodgson, Carol32; Hylander Møller, Morten33; Iwashyna, Theodore34; Jacob, Shevin35; Kleinpell, Ruth36; Klompas, Michael37; Koh, Younsuck38; Kumar, Anand39; Kwizera, Arthur40; Lobo, Suzana41; Masur, Henry42; McGloughlin, Steven43; Mehta, Sangeeta44; Mehta, Yatin45; Mer, Mervyn46; Nunnally, Mark47; Oczkowski, Simon48; Osborn, Tiffany49; Papathanassoglou, Elizabeth50; Perner, Anders51; Puskarich, Michael52; Roberts, Jason53; Schweickert, William54; Seckel, Maureen55; Sevransky, Jonathan56; Sprung, Charles L.57; Welte, Tobias58; Zimmerman, Janice59; Levy, Mitchell60. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Critical Care Medicine 49(11):p e1063-e1143, November 2021. | DOI: 10.1097/CCM.0000000000005337  Fan E, Del Sorbo L, Goligher EC, Hodgson CL, Munshi L, Walkey AJ, Adhikari NKJ, Amato MBP, Branson R, Brower RG, Ferguson ND, Gajic O, Gattinoni L, Hess D, Mancebo J, Meade MO, McAuley DF, Pesenti A, Ranieri VM, Rubenfeld GD, Rubin E, Seckel M, Slutsky AS, Talmor D, Thompson BT, Wunsch H, Uleryk E, Brozek J, Brochard LJ; American Thoracic Society, European Society of Intensive Care Medicine, and Society of Critical Care Medicine. An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2017 May 1;195(9):1253-1263. doi: 10.1164/rccm.201703-0548ST. Erratum in: Am J Respir Crit Care Med. 2017 Jun 1;195(11):1540. doi: 10.1164/rccm.19511erratum. PMID: 28459336. Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A, Du B, Aboodi M, Wunsch H, Cecconi M, Koh Y, Chertow DS, Maitland K, Alshamsi F, Belley-Cote E, Greco M, Laundy M, Morgan JS, Kesecioglu J, McGeer A, Mermel L, Mammen MJ, Alexander PE, Arrington A, Centofanti JE, Citerio G, Baw B, Memish ZA, Hammond N, Hayden FG, Evans L, Rhodes A. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19). Crit Care Med. 2020 Jun;48(6):e440-e469. doi: 10.1097/CCM.0000000000004363. PMID: 32224769; PMCID: PMC7176264. Wang W, Scharfstein D, Wang C, Daniels C, Needham D, Brower R, NHLBI ARDS Clinical Network. Estimating the Causal Effect of Low Tidal Volume Ventilation on Survival in Patients with Acute Lung Injury. J R Stat Soc Ser C Appl Stat. 2011. PMC: PMC3197806 Brower RG, Thompson BT, NIH/NHLBI/ARDSNetwork. Tidal volumes in acute respiratory distress syndrome--one size does not fit all. Crit Care Med. 2006. Hager DN, Krishman JA, Hayden D, Brower RG, ARDSNet NIH / NHLBI. Tidal Volume Reduction in Patients with acute Lung Injury When Plateau Pressures Are Not High. Am J Resp Crit Care Med. 2005. Rubenfeld GD, Cooper C, Carter G, Thompson BT, Hudson LD. Barriers to providing lung protective ventilation to patients with acute lung injury. Crit Care Med. 2004. Chatburn RL, El-Khatib M, Mireles-Cabodevila E. A taxonomy for mechanical ventilation: 10 fundamental maxims. Respir Care. 2014 Nov;59(11):1747-63. doi: 10.4187/respcare.03057. Epub 2014 Aug 12. PMID: 25118309. Guo L, Wang W, Zhao N, Guo L, Chi C, Hou W, Wu A, Tong H, Wang Y, Wang C, Li E. Mechanical ventilation strategies for intensive care unit patients without acute lung injury or acute respiratory distress syndrome: a systematic review and network meta-analysis. Crit Care. 2016 Jul 22;20(1):226. doi: 10.1186/s13054-016-1396-0. PMID: 27448995; PMCID: PMC4957383. Rice TW, Wheeler AP, Bernard GR, Hayden DL, Schoenfeld DA, Ware LB, NIH NHLBI ARDS Network. Comparison of the Sp02/FI02 Ratio and the PaO 2/FI02 in Patients with Acute Lung Injury or ARDS. Chest. 2007. Zhang G, Burla MJ, Caesar BB, Falank CR, Kyros P, Zucco VC, Strumilowska A, Cullinane DC, Sheppard FR. Emergency Department SpO2/FiO2 Ratios Correlate with Mechanical Ventilation and Intensive Care Unit Requirements in COVID-19 Patients. West J Emerg Med. 2024 May;25(3):325-331. doi: 10.5811/westjem.17975. PMID: 38801037; PMCID: PMC11112664.   WANT TO WORK AT MAYO? EM Physicians: https://jobs.mayoclinic.org/emergencymedicine EM NP PAs: https://jobs.mayoclinic.org/em-nppa-jobs   Nursing/Techs/PAC: https://jobs.mayoclinic.org/Nursing-Emergency-Medicine EMTs/Paramedics: https://jobs.mayoclinic.org/ambulanceservice All groups above combined into one link: https://jobs.mayoclinic.org/EM-Jobs

Wissensnachrichten - Deutschlandfunk Nova
Arbeitsanreize, Selbstzerstörungsplanet, Haarrecycling

Wissensnachrichten - Deutschlandfunk Nova

Play Episode Listen Later Jul 4, 2025 5:00


Die Themen in den Wissensnachrichten: +++ Wie ein niedriger Mindestlohn die Lust aufs Arbeiten dämpft +++ Wie sich ein Exoplanet mit einem Stern anlegt und dadurch selbst zerstört +++ Wie abgeschnittene Haare helfen können, Wasser zu sparen +++**********Weiterführende Quellen zu dieser Folge:The Welfare versus Work Paradox, Plos One, 06.05.2025Oscillations in incident electric field enhances interfacial water evaporation, Materials Horizons, 13.06.2025Wild Vanilla and pollinators at risk of spatial mismatch in a changing climate, Frontiers in Plant Science, 03.07.2025Close-in planet induces flares on its host star, nature, 02.07.2025How much we express love predicts how much we feel loved in daily life, Plos One, 2.7.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Wissensnachrichten - Deutschlandfunk Nova
Emojis, Waldbaden, interstellares Objekt

Wissensnachrichten - Deutschlandfunk Nova

Play Episode Listen Later Jul 3, 2025 6:01


Die Themen in den Wissensnachrichten: +++ Emojis lassen unsere Nachrichten freundlicher rüberkommen +++ Auch virtuelles Waldbaden hilft bei Stress +++ Weitgereister Gast fliegt durch unser Sonnensystem +++**********Weiterführende Quellen zu dieser Folge:The impact of emojis on perceived responsiveness and relationship satisfaction in text messaging, Plos One, 02.07.2025New World Screwworm, Animal and Plant Health Inspection Service U.S. DEPARTMENT OF AGRICULTURE, 02.07.2025US to breed billions of flies and dump them out of aircraft in bid to fight flesh-eating maggot, The Guardian, 02.07.2025Men and women's waking patterns to infant crying: Preparenthood differences are insufficient to explain uneven sharing of nighttime care, Emotions, 06.2025Myth busted: Men don't sleep through baby cries after all, Aarhus University, 01.07.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Emergency Medical Minute
Episode 963: Antihypertensives and Emergency Room Considerations

Emergency Medical Minute

Play Episode Listen Later Jun 30, 2025 4:07


Contributor: Alec Coston, MD Educational Pearls: For patients presenting to the emergency room with hypertension, clinicians should determine if it is isolated and uncomplicated, or involves comorbidities with more complex underlying pathophysiology.  For uncomplicated and isolated hypertension, first-line treatment is thiazide diuretics.  How do thiazide diuretics work to treat hypertension? Thiazide diuretics work by blocking sodium and chloride resorption in the kidneys.  “Where sodium goes, water follows,” thus promoting diuresis and lowering blood pressure. Examples of thiazide diuretics and their benefits? Hydrochlorothiazide (HCTZ): First-line medication in uncomplicated and chronic hypertensive states. Cheaper and fewer significant adverse effects compared to chlorthalidone. HCTZ can be associated with decreased risk of stroke and myocardial infarction. However, for more complicated hypertension, especially in the setting of heart failure, Angiotensin Converting Enzyme (ACE) Inhibitors should be considered.  How do ACE Inhibitors manage blood pressure? The body's kidneys drive the Renin-Angiotensin-Aldosterone-System (RAAS) to regulate blood pressure. It is easiest to understand RAAS as being pro-hypertensive as a response to decreased renal perfusion. As renal perfusion decreases, renin is released and activates angiotensin I, which is converted by ACE to Angiotensin II, which causes release of aldosterone. ACE Inhibitors prevent the conversion of Angiotensin I to Angiotensin II, thus decreasing the kidneys' production of Angiotensin II and Aldosterone levels. Why, in the context of heart failure, are ACE Inhibitors preferred? In heart failure, especially left-sided or left-ventricular heart failure, a vicious cycle can develop wherein the left ventricle fails to perfuse the kidneys due to over-dilation. The kidneys are hypoperfused and activate RAAS to try to retain volume and increase peripheral vasoconstriction, promoting renal perfusion. The increase in blood pressure puts further strain on the heart, thereby further decreasing cardiac output. The cycle develops, and extremely elevated blood pressures can develop. ACE Inhibitors can directly block this cycle, hence their preference in heart failure. Big takeaway? In uncomplicated hypertensive patients, consider thiazide diuretics. When comorbidities, especially heart failure, are introduced, then consider ACE Inhibitors. References Carey RM, Moran AE, Whelton PK. Treatment of Hypertension: A Review. JAMA. 2022;328(18):1849-1861. doi:10.1001/jama.2022.19590 Fan M, Zhang J, Lee CL, Zhang J, Feng L. Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. Nature. 2023;614(7949):788-793. doi:10.1038/s41586-023-05718-0 Hripcsak G, Suchard MA, Shea S, et al. Comparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension. JAMA Internal Medicine. 2020;180(4):542-551. doi:10.1001/jamainternmed.2019.7454 Yu D, Li JX, Cheng Y, et al. Comparative efficacy of different antihypertensive drug classes for stroke prevention: A network meta-analysis of randomized controlled trials. PLoS One. 2025;20(2):e0313309. doi:10.1371/journal.pone.0313309 Summarized by Dan Orbidan, OMS2 | Edited by Dan Orbidan & Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/  

Wissensnachrichten - Deutschlandfunk Nova
Nickerchen, Todesfälle, Katzen-Miauen

Wissensnachrichten - Deutschlandfunk Nova

Play Episode Listen Later Jun 27, 2025 4:53


Die Themen in den Wissensnachrichten: +++ Ein kurzer, tiefer Mittagsschlaf sorgt für Aha-Momente +++ Viele Menschen - vor allem Männer - sterben an vermeidbaren Krankheiten +++ Katzen-Miau liegt in den Genen +++**********Weiterführende Quellen zu dieser Folge:Klimapodcast Update Erde zum Thema ÜberdüngungN2 sleep promotes the occurrence of ‘aha' moments in a perceptual insight task, Plos Biology, 26.6.2025Avoidable mortality, risk factors and policies for tackling noncommunicable diseases – leveraging data for impact, WHO, 27.06.2025Association between androgen receptor gene and behavioral traits in cats (Felis catus), Plos One, 28.05.2025Radioactive waste: a scientific mission sets out to map submerged barrels in the Atlantic, CNRS 2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Hörsaal - Deutschlandfunk Nova
Mental Health und Social Media - Das Geschäft mit unserer Psyche

Hörsaal - Deutschlandfunk Nova

Play Episode Listen Later Jun 26, 2025 42:24


Ein Vortrag der Soziologin Laura WiesböckModeration: Katrin Ohlendorf**********Psychische Gesundheit ist ein großes Thema in den sozialen Medien – und das ist gut so, denn das trägt zur Enttabuisierung bei. Aber der Mental-Health-Trend ist auch ein Problem, findet Laura Wiesböck. Warum, das erklärt sie in diesem Vortrag.Laura Wiesböck ist Soziologin und arbeitet in Wien. Zurzeit leitet sie dort die Junior Research Group "Digitalisierung und soziale Transformation" am Institut für Höhere Studien. Sie forscht zum Thema soziale Ungleichheit mit besonderem Schwerpunkt auf Arbeit, Armut, Geschlecht und Digitalisierung. Zum Thema Psychische Gesundheit als Social Media Trend hat sie das Buch "Digitale Diagnosen" geschrieben, erschienen Anfang 2025.Ihren Vortrag "Legitime Überforderung: Psychiatrische Diagnosen im Kontext digitaler 'Mental Health'-Diskurse" hielt sie am 21. März 2025 im Rahmen der Suttner-Vorlesungen an der Bertha von Suttner Privatuniversität.**********+++ Deutschlandfunk Nova +++ Hörsaal +++ Vortrag +++ Gesundheit +++ Krankheit +++ Krise +++ Mental Health +++ Psyche +++ Psychische Gesundheit +++ Seele +++ Seelische Gesundheit +++ Selfcare +++ Selbstfürsorge +++ Social Media +++ Soziale Medien +++ Instagram +++ Youtube +++ Tiktok +++ Internet +++ Selbstdiagnose +++ Eigendiagnose +++ Onlinediagnose +++ Digitale Diagnose +++ Diagnostik +++ Symptome +++ ADHS +++ Depression +++ Angststörung +++ Autismus +++ Trauma +++ Trigger +++ toxisch +++ Influencer +++ Healthfluencer +++ Healthism +++ Tabu +++ Enttabuisierung +++ Pathologisierung +++ Psychotherapie +++ Therapie +++ Psychologie +++ Heilung +++**********Dieses Thema beschäftigt dich?Hier findest du eine Übersicht zu Hilfsangeboten**********Quellen aus der Folge:Karasavva V, Miller C, Groves N, Montiel A, Canu W, et al. (2025) A double-edged hashtag: Evaluation of #ADHD-related TikTok content and its associations with perceptions of ADHD. PLOS ONE 20(3): e0319335Yeung A, Ng E, Abi-Jaoude E. TikTok and Attention-Deficit/Hyperactivity Disorder: A Cross-Sectional Study of Social Media Content Quality. The Canadian Journal of Psychiatry. 2022;67(12):899-906**********Mehr zum Thema bei Deutschlandfunk Nova:Einsamkeit: Gefahr für Körper und SeeleResilienz: Wie wir uns selber krisenfest machenPsychologie: Wie Körperideale entstehen**********Den Artikel zum Stück findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

Nudge
I debunked psychology's greatest myth

Nudge

Play Episode Listen Later Jun 23, 2025 25:02


I interviewed 60 Brits to debunk one of psychology's greatest myths. Priming is one of the best-known biases in behavioural science. Kahneman mentions it 35 times in his best-selling book Thinking Fast and Slow. And yet, I'm not convinced it really works. In five separate experiments, I tested it. Does priming work, or is it a myth?  The studies:  Authenticity study: https://ibb.co/5W14DM2N Creativity study: https://ibb.co/FbxxNMDf Guilty study: https://ibb.co/XrTLXrY4 Anchoring + priming study: https://ibb.co/99LLw7G9 Reading time study: https://ibb.co/LDYc18yF ---  Subscribe to the (free) Nudge Newsletter: https://nudge.ck.page/profile Connect on LinkedIn: https://www.linkedin.com/in/phill-agnew-22213187/ Watch Nudge on YouTube: https://www.youtube.com/@nudgepodcast/ Learn more about Voxpopme: https://www.voxpopme.com/ ---  Sources:  Bargh, J. A., Chen, M., & Burrows, L. (1996). Automaticity of social behavior: Direct effects of trait construct and stereotype activation on action. Journal of Personality and Social Psychology, 71(2), 230–244. Chernev, A. (2011). Semantic anchoring in sequential evaluations of vices and virtues. Journal of Consumer Research, 37(5), 761–774. Doyen, S., Klein, O., Pichon, C. L., & Cleeremans, A. (2012). Behavioral priming: It's all in the mind, but whose mind? PLoS ONE, 7(1), e29081. Fitzsimons, G. J., Chartrand, T. L., & Fitzsimons, G. M. (2008). Automatic effects of brand exposure on motivated behavior: How Apple makes you “think different”. Journal of Consumer Research, 35(1), 21–35. Goldsmith, K., Cho, E., & Dhar, R. (2012). Priming creativity: The effects of subliminal priming on creative problem solving. In Z. Gürhan-Canli, C. Otnes, & R. Zhu (Eds.), Advances in Consumer Research (Vol. 40, pp. 472–473). Association for Consumer Research. Kahneman, D. (2011). Thinking, fast and slow. Farrar, Straus and Giroux. Kahneman, D. (2012, September 26). A letter to the priming research community [Open email].

Communicable
Communicable E29: Bacterial vaginosis & male partners

Communicable

Play Episode Listen Later Jun 15, 2025 59:33


Bacterial vaginosis (BV) was long considered not to be a sexually transmitted infection (STI), and treatment was only for women to bear. That was the convention at least until Catriona Bradshaw and her team at the Melbourne Sexual Health Centre published their groundbreaking clinical trial results earlier this year, demonstrating that treating male partners of women with BV prevented recurrence in those women. In this episode of Communicable, hosts Angela Huttner and Annie Joseph welcome back Bradshaw to discuss her trial's design, results, and clinical implications—with some guidelines already updated to include male partners in BV treatment regimens. The conversation also explores the complexities of BV diagnosis, the challenges of trial execution in general, and future research directions.This episode was edited by Kathryn Hostettler and peer reviewed by Arjana Zerja (Mother Theresa University Hospital Centre, Tirana, Albania)ReferencesVodstricil LA, et al. Male-partner treatment to prevent recurrence of bacterial vaginosis. N Engl J Med 2025. DOI: 10.1056/NEJMoa2405404Bacterial vaginosis in focus. Melbourne Sexual Health Centre (MSHC). https://www.mshc.org.au/sexual-health/bacterial-vaginosisFurther readingAuvert B, et al. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial. PLoS Med 2005. DOI: 10.1371/journal.pmed.0020298Bailey RC, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet 2007. DOI: 10.1016/S0140-6736(07)60312-2Bukusi E, et al. Topical penile microbicide use by men to prevent recurrent bacterial vaginosis in sex partners: A randomized clinical trial, Sex Transmi Dis 2011. DOI: 10.1097/OLQ.0b013e318214b82dCohen CR, et al. Randomized trial of Lactin-V to prevent recurrence of bacterial vaginosis. N Engl J Med 2020. DOI: 10.1056/NEJMoa1915254Gray RH, et al. The effects of male circumcision on female partners' genital tract symptoms and vaginal infections in a randomized trial in Rakai, Uganda, Am J Obstet Gynecol 2009. DOI: 10.1016/j.ajog.2008.07.069King AJ, et al. Getting Everyone on Board to Break the Cycle of Bacterial Vaginosis (BV) Recurrence: A Qualitative Study of Partner Treatment for BV. Patient 2025. DOI: 10.1007/s40271-025-00731-zMehta S, et al. The microbiome composition of a man's penis predicts incident bacterial vaginosis in his female sex partner with high accuracy, Front Cell Infect Microbiol 2020. DOI: 10.3389/fcimb.2020.00433Muzny CA, et al. An Updated Conceptual Model on the Pathogenesis of Bacterial Vaginosis. J Infect Dis 2019 DOI: 10.1093/infdis/jiz342Mitchell CM, et al. Screening and characterization of vaginal fluid donations for vaginal microbiota transplantation, Sci Rep 2022. DOI: 10.1038/s41598-022-22873-yPlummer EL, et al. A Prospective, Open-Label Pilot Study of Concurrent Male Partner Treatment for Bacterial Vaginosis. mBio 2021. DOI: 10.1128/mBio.02323-21Plummer EL, et al. Combined oral and topical antimicrobial therapy for male partners of women with bacterial vaginosis: Acceptability, tolerability and impact on the genital microbiota of couples - A pilot study. PLoS One 2018. DOI: 10.1371/journal.pone.0190199Vodstrcil LA, et al. Bacterial vaginosis: drivers of recurrence and challenges and opportunities in partner treatment. BMC Med 2021. DOI: 10.1186/s12916-021-02077-3Wawer MJ, et al. Wawer MJ, et al. Circumcision in HIV-infected men and its effect on HIV transmission to female partners in Rakai, Uganda: A randomised controlled trial. Lancet 2009. DOI: 10.1016/S0140-6736(09)60998-3

Synapsen. Ein Wissenschaftspodcast von NDR Info
(126) Wie gefährlich ist Hitzestress?

Synapsen. Ein Wissenschaftspodcast von NDR Info

Play Episode Listen Later Jun 6, 2025 67:42


Der Klimawandel bringt auch in Deutschland mehr Hitze und damit Gesundheitsrisiken. Wie können wir uns anpassen? Mehr Hitzetage im Sommer, häufigere Hitzewellen - und schon in 25 Jahren Temperaturen wie am Mittelmeer? Der Klimawandel wirkt sich auch auf Nordeuropa aus. Und das ist offenbar selbst für junge, gesunde Menschen nicht egal. Neueren Forschungen zufolge werden kritische Werte viel früher erreicht als lange angenommen. Unsere Autorin Nele Rößler hat mit Extremmedizinern, Kardiologen und Allergieforscherinnen gesprochen und die Risiken für ältere Menschen, Kinder, Diabetiker, Asthmatiker und Schwangere recherchiert. Im Gespräch mit Host Korinna Hennig berichtet sie von einem wichtigen Experiment in der Hitzekammer und erklärt, warum die "gefühlte Temperatur" auch ein wissenschaftlich belastbarer Wert sein kann. Die beiden besprechen, wie wir uns künftig im Alltag anpassen können. Und: Gemeinsam nehmen Nele und Korinna ein Projekt unter die Lupe, das als Paradebeispiel der Klimaanpassung gefeiert wird - und vielleicht doch zu viel verspricht. HINTERGRUNDINFORMATIONEN 1. Einfluss der unterschiedlichen Klimaszenarien auf die Sterblichkeit https://www.nature.com/articles/s41591-024-03452-2 2. 27 Grad - die Wohlfühltemperatur des Menschen. Eine Reise durch die Physiologie. http://physiologie.cc/XVIII.4.htm 3. Warum hat der Körper 37 Grad? Bild der Wissenschaft, 2011 https://www.wissenschaft.de/erde-umwelt/warum-misst-der-menschliche-koerper-37-grad-celsius/ 4. Einfluss der Luftfeuchtigkeit auf die Sterblichkeit, Environmental Health Perspectives 2023 https://ehp.niehs.nih.gov/doi/10.1289/EHP11807 5. Schwitzen im Alter, AOK, 2021 https://www.aok.de/pk/magazin/koerper-psyche/haut-und-allergie/schwitzen-im-alter/ 6. Demographischer Wandel in Deutschland, Statistisches Bundesamt https://www.destatis.de/DE/Themen/Querschnitt/Demografischer-Wandel/_inhalt.html#sprg371138 7. Zusammenhang zwischen hohen Temperaturen und Frühgeburten, British Medical Journal, 2020 https://www.bmj.com/content/371/bmj.m3811 8. Klimawandel und Allergien, AllergoJournal, 2022 https://pubmed.ncbi.nlm.nih.gov/35757154/ 9. Positive Auswirkungen des Montreal-Protokolls auf die FCKW-Werte, Nature, 2025 https://www.nature.com/articles/s41586-025-08640-9 10. Wie stark erwärmen sich Madrid, Moskau, Barcelona und Co.? Den Klimawandel besser verstehen durch den weltweiten Vergleich von Städten, Plos One, 2019 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217592 11. Hitzesterblichkeit durch Stadtbegrünung verringern, The Lancet Planetary Health, 2025 https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(25)00062-2/fulltext 12. Erwärmung des urbanen Raums im Vergleich zum Land, Helmholtz Klima, abgerufen April 2025 https://www.helmholtz-klima.de/klimawissen/macht-der-klimawandel-unsere-staedte-zu-hitzeinseln

Your Diet Sucks
What the Science Really Says About Diet and Longevity

Your Diet Sucks

Play Episode Listen Later May 28, 2025 66:13


Join our Patreon and get access to monthly bonus episodes and more nutriton content!Can fasting really slow aging? Does calorie restriction work for humans, or just for mice and yeast? And how much protein do you actually need to age well? This week on Your Diet Sucks, we break down the evidence behind the most talked-about interventions in the longevity space, what holds up under scrutiny, what doesn't, and why you might not need a supplement stack to live longer, and enjoy life. We dig into:The actual science on calorie restriction, fasting, and supplements—and where the evidence stopsWhat inflammation, oxidative stress, and telomeres have to do with how we ageThe best-researched dietary patterns for living longer (hint: it's not sexy, but it might include red wine)Why protein becomes more important as we ageThe difference between lifespan and healthspan, and why quality of life needs to be part of the conversation

Heal NPD
Weekly Insights: The Myth of Hardwired Narcissism

Heal NPD

Play Episode Listen Later May 27, 2025 12:17


In this video, Dr. Ettensohn examines the growing claim that Narcissistic Personality Disorder (NPD) is almost entirely genetic, offering a critical, clinically grounded reflection on what the current science actually supports—and where it falls short. He discusses how genetic contributions to personality traits are often misunderstood, and why claims of “hardwired narcissism” oversimplify a profoundly complex developmental process. Drawing from empirical research, neurodevelopmental theory, and clinical observation, Dr. Ettensohn explores how narcissistic pathology emerges not simply from temperament, but from early relational experiences—especially chronic emotional neglect, inconsistent attunement, and conditional regard. He addresses how brain plasticity, diagnostic controversies, and the misunderstood vulnerable core of NPD further complicate the genetic narrative. This video offers a nuanced perspective for anyone seeking to understand NPD beyond reductive models, emphasizing the importance of relational context, developmental history, and psychological depth. References: Brummelman, E., Thomaes, S., Nelemans, S. A., Orobio de Castro, B., Overbeek, G., & Bushman, B. J. (2015). Origins of narcissism in children. Proceedings of the National Academy of Sciences, 112(12), 3659–3662. https://doi.org/10.1073/pnas.1420870112 Chen, Y., Jiang, X., Sun, Y., & Wang, Y. (2023). Neuroanatomical markers of social cognition in neglected adolescents. NeuroImage: Clinical, 38, 103501. https://doi.org/10.1016/j.nicl.2023.103501 Gatz, M., Reynolds, C. A., Fratiglioni, L., Johansson, B., Mortimer, J. A., Berg, S., & Pedersen, N. L. (2006). Role of genes and environments for explaining Alzheimer disease. Archives of General Psychiatry, 63(2), 168–174. https://doi.org/10.1001/archpsyc.63.2.168 Horton, R. S., Bleau, G., & Drwecki, B. (2006). Parenting Narcissus: What are the links between parenting and narcissism? Journal of Personality, 74(2), 345–376. https://doi.org/10.1111/j.1467-6494.2005.00380.x Luo, Y. L. L., Cai, H., & Song, H. (2014). A behavioral genetic study of intrapersonal and interpersonal dimensions of narcissism. PLOS ONE, 9(4), e93403. https://doi.org/10.1371/journal.pone.0093403 Nenadić, I., Lorenz, C., & Gaser, C. (2021). Narcissistic personality traits and prefrontal brain structure. Scientific Reports, 11, 15707. https://doi.org/10.1038/s41598-021-94920-z Otway, L. J., & Vignoles, V. L. (2006). Narcissism and childhood recollections: A quantitative test of psychoanalytic predictions. Personality and Social Psychology Bulletin, 32(1), 104–116. https://doi.org/10.1177/0146167205279907 Schulze, L., Dziobek, I., Vater, A., Heekeren, H. R., Bajbouj, M., Renneberg, B., & Roepke, S. (2013). Gray matter abnormalities in patients with narcissistic personality disorder. Journal of Psychiatric Research, 47(10), 1363–1369. https://doi.org/10.1016/j.jpsychires.2013.05.017 Skodol, A. E. (2012). The revision of personality disorder diagnosis in DSM-5: What's new? Current Psychiatry Reports, 14(1), 39–43. https://doi.org/10.1007/s11920-011-0243-2

Quirks and Quarks Complete Show from CBC Radio
Why the Information Age seems so overwhelming, and more...

Quirks and Quarks Complete Show from CBC Radio

Play Episode Listen Later May 16, 2025 54:09


Chimpanzees use medicinal plants for first aid and hygieneResearchers have observed wild chimpanzees seeking out particular plants, including ones known to have medicinal value, and using them to treat wounds on themselves and others. They also used plants to clean themselves after sex and defecation. Elodie Freymann from Oxford University lived with the chimpanzees in Uganda over eight months and published this research in the journal Frontiers in Ecology and Evolution.Why this evolutionary dead end makes understanding extinction even more difficult540 million years ago, there was an explosion of animal diversity called the Cambrian explosion, when nature experimented with, and winnowed many animal forms into just a few. A new discovery of one of the unlucky ones that didn't make it has deepened the mystery of why some went extinct, because despite its strangeness, it shows adaptations common to many of the survivors. Joseph Moysiuk, curator of paleontology and geology at the Manitoba Museum helped identify the fossil, and published on it in Royal Society Open Science A quantum computer demonstrates its worth by solving an impossible puzzleImagine taking a sudoku puzzle, handing bits of it to several people, putting them in separate rooms, and asking them to solve the puzzle. A quantum computer using the weird phenomenon of “entanglement” was able to do something analogous to this, which serves as evidence that it really is exploiting quantum strangeness, and could be used for more practical purposes. David Stephen, a physicist at the quantum computing company Quantinuum, and colleagues from the University of Boulder published on this finding in Physical Review Letters.Roadkill shows that most mammals have fluorescent furA researcher who used a range of mammal and marsupial animals killed by vehicles, has demonstrated that the fur of many of these animals exhibit biofluorescence – the ability to absorb light and re-emit it in different wavelengths. They were able to identify some of the fluorescent chemicals, but don't know why these animals would glow like this. Zoologist Linda Reinhold observed bright colours such as yellow, blue, green and pink on Australian animals like the bandicoot, wallaby, tree-kangaroo, possums and quolls. Their research was published in the journal PLOS One.Science suggests humans are not built for the information ageWe are living in the age of information. In fact, we're drowning in it. Modern technology has put vast amounts of information at our fingertips, and it turns out that science is showing that humans just aren't that good at processing all that data, making us vulnerable to bias, misinformation and manipulation.Producer Amanda Buckiewicz spoke to:Friedrich Götz, an Assistant Professor of Psychology at the University of British Columbia.Vasileia Karasavva, a PhD student in the Department of Psychology at the University of British Columbia.Timothy Caulfield, professor in the Faculty of Law and the School of Public Health at the University of Alberta, and was the Canada Research Chair in Health Law and Policy from 2002 - 2023.Eugina Leung, an assistant professor of marketing at the A.B. Freeman School of Business at Tulane University.Jonathan Kimmelman, a medical ethicist based at McGill University.

The Flipping 50 Show
Protein for Menopause Hormone Support

The Flipping 50 Show

Play Episode Listen Later May 9, 2025 49:50


Let's unpack something most midlife women are totally missing – protein for Menopause Hormone Support. Are you feeling moody, low-energy, or constantly craving carbs in midlife? It might not just be your hormones—it could be your protein intake… and its effect on your hormones.  In today's episode, know how protein connects hormones and why your daily meals might be the hormonal tune-up you didn't know you needed. Cortisol & Protein: The Stress-Balance Dance Cortisol levels increase in response to low blood sugar or stress, which are common when meals are high-carb and low-protein. A high-protein diet blunts cortisol spikes post-meal and improves the body's stress response.   Insulin: Protein's Role in Glucose Control Protein stimulates insulin—but in a modulated way that helps with blood sugar stability, not spikes. In midlife and beyond, protein helps preserve insulin sensitivity, especially when combined with resistance training.   Ghrelin & Leptin: Protein vs. Cravings Ghrelin = your hunger hormone. Protein is the most effective macronutrient at suppressing ghrelin. Leptin = satiety hormone. Protein helps regulate leptin sensitivity over time. The Protein theory goes that if the body doesn't get enough protein it will message you it wants more. The problem is the message is not clear. It's just a hunger signal. You're left to figure it out or deal with the tempting cookies, cakes, and chocolate hidden in the icebox.    Estrogen: From Muscle Protector to MIA Estrogen is an anabolic hormone—it supports muscle maintenance, insulin sensitivity, and metabolic efficiency. As estrogen declines in perimenopause and menopause, its natural support of muscle protein synthesis (MPS) disappears. With estrogen no longer stimulating MPS, women must now rely on two primary tools to stimulate it: Resistance training Adequate high-quality protein (especially leucine-rich) “Estrogen enhances the anabolic response of skeletal muscle to both feeding and resistance exercise, and its loss results in anabolic resistance.”   More Truths About Protein for Menopause Hormone Support Muscle Protein Synthesis declines with age—and even more so without estrogen.  This is why RDA-level protein (0.8g/kg) is not sufficient in midlife - a statement agreed on by Registered Dietitians, longevity and geriatric experts alike.  Experts (ISSN) recommend ≥1.6–2.2g/kg of body weight for active women in midlife to maintain muscle, metabolism, and hormonal resilience.   The Anabolic vs. Catabolic Hormone Framework Anabolic Hormones = Build & Repair These are hormones that stimulate tissue growth and regeneration: Testosterone – promotes muscle growth, strength, libido Growth Hormone (GH) – supports repair, recovery, and fat metabolism Estrogen – helps preserve lean mass, regulates insulin sensitivity Insulin – can be anabolic by shuttling nutrients into cells, especially post-exercise Protein intake supports all of these by providing the amino acid building blocks needed for anabolic activity. Catabolic Hormones = Break DownThese are hormones that promote the breakdown of muscle, tissue, and energy stores: Cortisol – breaks down muscle for glucose during stress Epinephrine/Norepinephrine – mobilize energy in fight-or-flight Chronically elevated catabolic hormones + low protein = muscle loss, cravings, fatigue. Fat Storage Insulin isn't actually a catabolic hormone but it does increase fat storage. You can't be burning fat if insulin is high, as is true for many women. Focusing on boosting the anabolic hormones is the game-changer.    Other Episodes You Might Like: Previous Episode - Can We Just Stop the Self Sabotage to Feel Your Best Ever  Next Episode - How and Why to Consider Meditation in Menopause More Like This - Where Protein Recommendations for Women Come From?   Resources:  This episode is brought to you by Flipping 50 Longevity Pro Protein & Fiber, the simplest ingredient, cleanest, third-party-tested protein powder formulated specifically for midlife metabolism. No bloat, no fillers, just functional fuel. Use code PODCAST10 for 10% off at checkout.   References:  Lemmens SG, Born JM, Martens EA, Martens MJ, Westerterp-Plantenga MS. PLoS One. 2011 Feb 3;6(2):e16826. doi: 10.1371/journal.pone.0016826. PMID: 21304815; PMCID: PMC3033415. Layman et al., 2008 reported that diets with higher protein and lower carbs improved insulin sensitivity in adults. DOI: 10.1093/jn/138.3.514 Leidy HJ, Ortinau LC, Douglas SM, Hoertel HA. Am J Clin Nutr. 2013 Apr;97(4):677-88. doi: 10.3945/ajcn.112.053116. Epub 2013 Feb 27. PMID: 23446906; PMCID: PMC3718776. Tang JE, Moore DR, Kujbida GW, Tarnopolsky MA, Phillips SM. J Appl Physiol (1985). 2009 Sep;107(3):987-92. doi: 10.1152/japplphysiol.00076.2009. Epub 2009 Jul 9. PMID: 19589961.  

I Hate James Dobson
Episode 30: Dobson v. Public Education

I Hate James Dobson

Play Episode Listen Later Apr 28, 2025 73:22


Public education was nice while we had it, too bad it's being lit on fire (like everything else). And yes, it is James Dobson's fault (also like everything else). Today, Jake and Brooke explore Dobson's influence in the homeschooling movement - and hear from the big D himself. So, you have that to look forward to in this episode I guess.References:Campbell, F. A., Pungello, E. P., Burchinal, M., Kainz, K., Pan, Y., Wasik, B. H., ... & Ramey, C. T. (2012). Adult outcomes as a function of an early childhood educational program: an Abecedarian Project follow-up. Developmental psychology, 48(4), 1033.Dobson, J. (Host). (2010, September 10). School Can Wait [Audio podcast episode]. In Family Talk. Focus on the Family. https://www.drjamesdobson.org/broadcasts/school-can-waitDobson, J. (Host). (2010, November 24). Update on Homeschooling [Audio podcast episode]. In Family Talk. Focus on the Family. https://www.drjamesdobson.org/broadcasts/update-on-homeschoolingHampton, G. (Director). (2022). Schoolhouse Rocked: The Homeschool Revolution. [YouTube Video]. Bronze Oxen Films LLCHeckman, J., Pinto, R., & Savelyev, P. (2013). Understanding the mechanisms through which an influential early childhood program boosted adult outcomes. American economic review, 103(6), 2052-2086.Lavin, T. (2024). Wild Faith: How the Christian Right is Taking Over America. Legacy Lit.McClelland, M. M., Acock, A. C., Piccinin, A., Rhea, S. A., & Stallings, M. C. (2013). Relations between preschool attention span-persistence and age 25 educational outcomes. Early childhood research quarterly, 28(2), 314-324.McCoy, D. C., Yoshikawa, H., Ziol-Guest, K. M., Duncan, G. J., Schindler, H. S., Magnuson, K., ... & Shonkoff, J. P. (2017). Impacts of early childhood education on medium-and long-term educational outcomes. Educational researcher, 46(8), 474-487.My blog research spreadsheet/mental breakdown: https://docs.google.com/spreadsheets/d/19fNvWgzwYTWy2xJrDUnv5eX1wlAKjIviWHzmOZd-GRc/edit?usp=sharing Reynolds, A. J., Temple, J. A., Ou, S. R., Arteaga, I. A., & White, B. A. (2011). School-based early childhood education and age-28 well-being: Effects by timing, dosage, and subgroups. Science, 333(6040), 360-364.von Suchodoletz A, Lee DS, Henry J, Tamang S, Premachandra B, Yoshikawa H (2023) Early childhood education and care quality and associations with child outcomes: A meta-analysis. PLoS ONE 18(5): e0285985. https://doi.org/ 10.1371/journal.pone.0285985Music from #Uppbeat (free for Creators!):https://uppbeat.io/t/mood-maze/trendsetterLicense code: 9OT2MTBHWWSRZP5S Hosted on Acast. See acast.com/privacy for more information.

Your Brain On
Your Brain On... Menopause

Your Brain On

Play Episode Listen Later Apr 24, 2025 61:07


Two-thirds of those diagnosed with Alzheimer's disease are women — but why? In this episode, we unpack the neurological, hormonal, and social drivers that uniquely affect women's brain health during the menopausal transition — from estrogen's protective role in the brain to the misunderstood history of hormone replacement therapy. We discuss: • Why women face a higher risk of Alzheimer's than men • How menopause accelerates brain aging (and how it starts earlier than is often expected) • The role of estrogen in brain metabolism and neuroprotection • The real story behind hormone replacement therapy (HRT) • The impact of genes like APOE4 on women's brain health • How lifestyle factors like stress, sleep, and cognitive activity can help reduce the impact of neurological changes onset by menopause ——— Get our free curation of women's brain health resources in our Brain Box: http://thebraindocs.com/brainbox ——— To help us tell this story, we welcome three world-renowned women's health experts to the podcast: DR. LISA MOSCONI: Director of the Women's Brain Initiative, author of ‘The Menopause Brain', and pioneering researcher in brain imaging and hormonal neuroscience. MARIA SHRIVER: Founder of the Women's Alzheimer's Movement, journalist, and relentless advocate for gender equity in brain health research. DR. LISA GENOVA: Neuroscientist and bestselling author of ‘Still Alice', which was adapted into a film starring Julianne Moore, who won the  2015 Best Actress Oscar for her role as Alice Howland. This is... Your Brain On Menopause. ‘Your Brain On' is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Menopause' • SEASON 5 • EPISODE 1 ——— Our free Women's Brain Health Brain Box includes: • Guides on how to speak with healthcare providers about menopause • Delicious brain-healthy Mother's Day brunch recipes • Meaningful gift ideas for the women you love • Inspiring interviews with world-leading women's health experts • And even a chance to check your cognitive health with an insightful, science-backed test Get the Brain Box for free! Here: http://thebraindocs.com/brainbox ——— References: Mosconi, L. (2017). Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery. PloS One, 12(10), e0185926.  Belloy, M. E. & Alzheimer's Disease Neuroimaging Initiative. (2019). A quarter century of APOE and Alzheimer's disease: Progress to date and the path forward. Neuron, 101(5), 820-838.  Rahman, A. (2019). Sex and gender driven modifiers of Alzheimer's: The role for estrogenic control across age, race, medical, and lifestyle risks. Frontiers in Aging Neuroscience, 11, 315.  Rocca, W. A. (2012). Hysterectomy, oophorectomy, estrogen, and the risk of dementia. Neurodegenerative Diseases, 10(1-4), 175-178.  Scheyer, O. (2018). Female sex and Alzheimer's risk: The menopause connection. Journal of Prevention of Alzheimer's Disease, 5(4), 225-230.  Women's Health Initiative Memory Study Investigators. (2003). Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: The Women's Health Initiative Memory Study—a randomized controlled trial. JAMA, 289(20), 2651–2662.  Women's Health Initiative Investigators. (2002). Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial. JAMA, 288(3), 321-333.  Whitmer, R. A. (2005). Midlife cardiovascular risk factors and risk of dementia in late life. Neurology, 64(2), 277-281.  Livingston, G. (2024). Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. The Lancet, 404(10452), 572-628. Maki, P. M. (2016). Hormone therapy, dementia, and cognition: The Women's Health Initiative 10 years on. Climacteric, 19(3), 313-315. 

Bob Enyart Live

Listen in as Real Science Radio host Fred Williams and co-host Doug McBurney review and update some of Bob Enyart's legendary list of not so old things! From Darwin's Finches to opals forming in months to man's genetic diversity in 200 generations, to carbon 14 everywhere it's not supposed to be (including in diamonds and dinosaur bones!), scientific observations simply defy the claim that the earth is billions of years old. Real science demands the dismissal of the alleged million and billion year ages asserted by the ungodly and the foolish.     * Finches Adapt in 17 Years, Not 2.3 Million: Charles Darwin's finches are claimed to have taken 2,300,000 years to diversify from an initial species blown onto the Galapagos Islands. Yet individuals from a single finch species on a U.S. Bird Reservation in the Pacific were introduced to a group of small islands 300 miles away and in at most 17 years, like Darwin's finches, they had diversified their beaks, related muscles, and behavior to fill various ecological niches. Hear about this also at rsr.org/spetner.  * Finches Speciate in Two Generations vs Two Million Years for Darwin's Birds?  Darwin's finches on the Galapagos Islands are said to have diversified into 14 species over a period of two million years. But in 2017 the journal Science reported a newcomer to the Island which within two generations spawned a reproductively isolated new species. In another instance as documented by Lee Spetner, a hundred birds of the same finch species introduced to an island cluster a 1,000 kilometers from Galapagos diversified into species with the typical variations in beak sizes, etc. "If this diversification occurred in less than seventeen years," Dr. Spetner asks, "why did Darwin's Galapagos finches [as claimed by evolutionists] have to take two million years?" * Opals Can Form in "A Few Months" And Don't Need 100,000 Years: A leading authority on opals, Allan W. Eckert, observed that, "scientific papers and textbooks have told that the process of opal formation requires tens of thousands of years, perhaps hundreds of thousands... Not true." A 2011 peer-reviewed paper in a geology journal from Australia, where almost all the world's opal is found, reported on the: "new timetable for opal formation involving weeks to a few months and not the hundreds of thousands of years envisaged by the conventional weathering model." (And apparently, per a 2019 report from Entomology Today, opals can even form around insects!) More knowledgeable scientists resist the uncritical, group-think insistence on false super-slow formation rates (as also for manganese nodules, gold veins, stone, petroleum, canyons and gullies, and even guts, all below). Regarding opals, Darwinian bias led geologists to long ignore possible quick action, as from microbes, as a possible explanation for these mineraloids. For both in nature and in the lab, opals form rapidly, not even in 10,000 years, but in weeks. See this also from creationists by a geologist, a paleobiochemist, and a nuclear chemist. * Blue Eyes Originated Not So Long Ago: Not a million years ago, nor a hundred thousand years ago, but based on a peer-reviewed paper in Human Genetics, a press release at Science Daily reports that, "research shows that people with blue eyes have a single, common ancestor. A team at the University of Copenhagen have tracked down a genetic mutation which took place 6-10,000 years ago and is the cause of the eye color of all blue-eyed humans alive on the planet today." * Adding the Entire Universe to our List of Not So Old Things? Based on March 2019 findings from Hubble, Nobel laureate Adam Riess of the Space Telescope Science Institute and his co-authors in the Astrophysical Journal estimate that the universe is about a billion years younger than previously thought! Then in September 2019 in the journal Science, the age dropped precipitously to as low as 11.4 billion years! Of course, these measurements also further squeeze the canonical story of the big bang chronology with its many already existing problems including the insufficient time to "evolve" distant mature galaxies, galaxy clusters, superclusters, enormous black holes, filaments, bubbles, walls, and other superstructures. So, even though the latest estimates are still absurdly too old (Google: big bang predictions, and click on the #1 ranked article, or just go on over there to rsr.org/bb), regardless, we thought we'd plop the whole universe down on our List of Not So Old Things!   * After the Soft Tissue Discoveries, NOW Dino DNA: When a North Carolina State University paleontologist took the Tyrannosaurus Rex photos to the right of original biological material, that led to the 2016 discovery of dinosaur DNA, So far researchers have also recovered dinosaur blood vessels, collagen, osteocytes, hemoglobin, red blood cells, and various proteins. As of May 2018, twenty-six scientific journals, including Nature, Science, PNAS, PLoS One, Bone, and Journal of Vertebrate Paleontology, have confirmed the discovery of biomaterial fossils from many dinosaurs! Organisms including T. Rex, hadrosaur, titanosaur, triceratops, Lufengosaur, mosasaur, and Archaeopteryx, and many others dated, allegedly, even hundreds of millions of years old, have yielded their endogenous, still-soft biological material. See the web's most complete listing of 100+ journal papers (screenshot, left) announcing these discoveries at bflist.rsr.org and see it in layman's terms at rsr.org/soft. * Rapid Stalactites, Stalagmites, Etc.: A construction worker in 1954 left a lemonade bottle in one of Australia's famous Jenolan Caves. By 2011 it had been naturally transformed into a stalagmite (below, right). Increasing scientific knowledge is arguing for rapid cave formation (see below, Nat'l Park Service shrinks Carlsbad Caverns formation estimates from 260M years, to 10M, to 2M, to it "depends"). Likewise, examples are growing of rapid formations with typical chemical make-up (see bottle, left) of classic stalactites and stalagmites including: - in Nat'l Geo the Carlsbad Caverns stalagmite that rapidly covered a bat - the tunnel stalagmites at Tennessee's Raccoon Mountain - hundreds of stalactites beneath the Lincoln Memorial - those near Gladfelter Hall at Philadelphia's Temple University (send photos to Bob@rsr.org) - hundreds of stalactites at Australia's zinc mine at Mt. Isa.   - and those beneath Melbourne's Shrine of Remembrance. * Most Human Mutations Arose in 200 Generations: From Adam until Real Science Radio, in only 200 generations! The journal Nature reports The Recent Origin of Most Human Protein-coding Variants. As summarized by geneticist co-author Joshua Akey, "Most of the mutations that we found arose in the last 200 generations or so" (the same number previously published by biblical creationists). Another 2012 paper, in the American Journal of Physical Anthropology (Eugenie Scott's own field) on High mitochondrial mutation rates, shows that one mitochondrial DNA mutation occurs every other generation, which, as creationists point out, indicates that mtEve would have lived about 200 generations ago. That's not so old! * National Geographic's Not-So-Old Hard-Rock Canyon at Mount St. Helens: As our List of Not So Old Things (this web page) reveals, by a kneejerk reaction evolutionary scientists assign ages of tens or hundreds of thousands of years (or at least just long enough to contradict Moses' chronology in Genesis.) However, with closer study, routinely, more and more old ages get revised downward to fit the world's growing scientific knowledge. So the trend is not that more information lengthens ages, but rather, as data replaces guesswork, ages tend to shrink until they are consistent with the young-earth biblical timeframe. Consistent with this observation, the May 2000 issue of National Geographic quotes the U.S. Forest Service's scientist at Mount St. Helens, Peter Frenzen, describing the canyon on the north side of the volcano. "You'd expect a hard-rock canyon to be thousands, even hundreds of thousands of years old. But this was cut in less than a decade." And as for the volcano itself, while again, the kneejerk reaction of old-earthers would be to claim that most geologic features are hundreds of thousands or millions of years old, the atheistic National Geographic magazine acknowledges from the evidence that Mount St. Helens, the volcanic mount, is only about 4,000 years old! See below and more at rsr.org/mount-st-helens. * Mount St. Helens Dome Ten Years Old not 1.7 Million: Geochron Laboratories of Cambridge, Mass., using potassium-argon and other radiometric techniques claims the rock sample they dated, from the volcano's dome, solidified somewhere between 340,000 and 2.8 million years ago. However photographic evidence and historical reports document the dome's formation during the 1980s, just ten years prior to the samples being collected. With the age of this rock known, radiometric dating therefore gets the age 99.99999% wrong. * Devils Hole Pupfish Isolated Not for 13,000 Years But for 100: Secular scientists default to knee-jerk, older-than-Bible-age dates. However, a tiny Mojave desert fish is having none of it. Rather than having been genetically isolated from other fish for 13,000 years (which would make this small school of fish older than the Earth itself), according to a paper in the journal Nature, actual measurements of mutation rates indicate that the genetic diversity of these Pupfish could have been generated in about 100 years, give or take a few. * Polystrates like Spines and Rare Schools of Fossilized Jellyfish: Previously, seven sedimentary layers in Wisconsin had been described as taking a million years to form. And because jellyfish have no skeleton, as Charles Darwin pointed out, it is rare to find them among fossils. But now, reported in the journal Geology, a school of jellyfish fossils have been found throughout those same seven layers. So, polystrate fossils that condense the time of strata deposition from eons to hours or months, include: - Jellyfish in central Wisconsin were not deposited and fossilized over a million years but during a single event quick enough to trap a whole school. (This fossil school, therefore, taken as a unit forms a polystrate fossil.) Examples are everywhere that falsify the claims of strata deposition over millions of years. - Countless trilobites buried in astounding three dimensionality around the world are meticulously recovered from limestone, much of which is claimed to have been deposited very slowly. Contrariwise, because these specimens were buried rapidly in quickly laid down sediments, they show no evidence of greater erosion on their upper parts as compared to their lower parts. - The delicacy of radiating spine polystrates, like tadpole and jellyfish fossils, especially clearly demonstrate the rapidity of such strata deposition. - A second school of jellyfish, even though they rarely fossilized, exists in another locale with jellyfish fossils in multiple layers, in Australia's Brockman Iron Formation, constraining there too the rate of strata deposition. By the way, jellyfish are an example of evolution's big squeeze. Like galaxies evolving too quickly, 

america university california world australia google earth science bible washington france space real nature africa european writing evolution philadelphia australian japanese dna minnesota tennessee modern hawaii wisconsin bbc 3d island journal nbc birds melbourne mt chile flash mass scientists abortion cambridge pacific increasing conservatives bone wyoming consistent generations iceland ohio state instant wired decades rapid nobel national geographic talks remembrance maui yellowstone national park wing copenhagen grand canyon chemical big bang nova scotia nbc news smithsonian secular daily mail telegraph temple university groundbreaking arial 2m screenshots papua new guinea helvetica 10m charles darwin variants death valley geology geo jellyfish american journal nps national park service hubble north carolina state university public libraries steve austin cambridge university press missoula galapagos geographic mojave organisms forest service diabolical aig darwinian veins mount st tyrannosaurus rex new scientist helens lincoln memorial plos one galapagos islands shri inky cambrian cmi pnas human genetics live science science daily canadian arctic opals asiatic spines canadian broadcasting corporation finches rsr park service two generations 3den spirit lake unintelligible junk dna carlsbad caverns space telescope science institute 260m archaeopteryx fred williams ctrl f nature geoscience from creation vertebrate paleontology from darwin 2fjournal physical anthropology eugenie scott british geological survey 3dtrue larval adam riess 252c raleway bob enyart ctowud oligocene 3dfalse jenolan caves ctowud a6t real science radio allan w eckert kgov
Science Friday
TikTok Is Shaping How We Think About ADHD

Science Friday

Play Episode Listen Later Apr 1, 2025 18:09


Mental health information on social media can be both revelatory and misleading. How do clinicians and their patients make sense of it?TikTok and other social media sites are full of mental health content—often short, grabby, first-person videos detailing symptoms for conditions like ADHD and autism. But what does this mean for teens and young adults who spend hours a day scrolling?A new study published in PLOS One analyzes the 100 most viewed TikTok videos about ADHD to assess both how accurate they are and how young people respond to them. Researchers found that about half of the videos were inaccurate or missing key context, and that the more TikToks young adults watched, the less critical they were of the content.For some, watching social videos about mental health conditions led them to better understand themselves and eventually get a proper diagnosis and treatment. For others it made them consider if they have conditions they don't meet the diagnostic criteria for.Host Flora Lichtman talks with the lead author of the ADHD TikTok study, Vasileia Karasavva, a PhD Student in clinical psychology at the University of British Columbia; and Dr. Jennifer Katzenstein, director of psychology, neuropsychology, and social work at Johns Hopkins All Children's Hospital in St. Petersburg, Florida.Transcripts for each segment will be available after the show airs on sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Short Wave
What Experts Say about ADHD-Tok

Short Wave

Play Episode Listen Later Mar 21, 2025 9:07


Ever diagnosed yourself with a mental health disorder based on a TikTok video? If so, you're not alone. "I personally don't think that there's anything more human than wanting to understand yourself and wanting to understand your own experiences," says Vasileia Karasavva. Vasileia is the lead author of a paper published Wednesday in the journal PLOS One that gets into why this kind of self-diagnosis can be such a double-edged sword.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy