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161 episodes with Jonathan Karp
3 episodes with Jonathan Karp
3 episodes with Jonathan Karp
Down syndrome, also known as Trisomy 21, is a common genetic condition affecting roughly 1 in 700 live births in the United States. A recent study that came out in February 2025 that studied skin cells from an individual with Down syndrome to determine if it was possible to genetically engineer the extra chromosome out of the DNA. This study's aim was to see if it was possible to use CRISPR-CAS9 (a technology used to modify genetic code and expression), to be able to completely knock out a chromosome. The reason these researchers used the DNA from an individual with Down syndrome was because the third chromosome is a clear marker that they can see easily to determine if they were successful or not. However, one Press Release article covering this research wrote a piece that incorrectly frames the study as a possible way to "cure" Down syndrome, which is not at all what the researchers were attempting to do. This week, Dr. Jonathan Karp and student producer Kaya Basatemur go through the details of this study, what the scientists' goals were, and why the Press Release article did not accurately describe anything that the researchers did. Tune in to find out more about this interesting study, possible future research, and practical uses of CRISPR-CAS9 genome editing technology!
As covered on some previous episodes of Health 411, the Press Release version of a Primary Literature article might not always be the most accurate one. This week, Dr. Jonathan Karp and student producer Kaya Basatemur dive into the differences and similarities between the PR and Primary Literature of a study done on Brain Organoids. What is a multi-region brain organoid, and why should we know the difference between one of these and a full adult brain? What were these scientists trying to accomplish, and did they accomplish it? Tune in to the latest episode of Health 411 to find out the answers to these burning questions and more.
When it comes to being an Emergency Room doctor, every day is something new. You can never really know what to expect each day- and it's more than likely to see a case you've never seen in a textbook before. Having to figure out how to treat patients in the moment to keep them alive is the job of every ER doctor, nurse, and technician. Today, Dr. Jonathan Karp and student producer Kaya Basatemur are joined by Dr. Mark Pappadakis from Capital Health to discuss what being an ER doctor is like. From his experiences in college and medical school to his day-to-day in the Emergency room, Dr. Pappadakis describes some of the most important things for you to know about the ER.
August 19th, 2025 was a great day for neuroscience. Why, you may ask? Because a paper published on Nature Aging discussed a breakthrough in being able to pinpoint a specific iron-associated protein in the Hippocampus related to age-related cognitive impairment. While numerous Press Release articles have made this sound like the cure to aging, this is not the case. Dr. Jonathan Karp and student producer Kaya Basatemur break this paper down into the steps these scientists took, and the logic behind their experiments and findings to determine if the PR articles have it right; is this truly the cure to aging, or is the media over exaggerating and generalizing specific findings? Listen in to find out in the newest episode of Health 411!
In recent years, the subject of primate research has become a controversial topic of discussion. Is it unethical? Are there too many primates being tested on? Are primates necessary to conduct certain studies? What are the specific goals of primate research? Today Dr. Jonathan Karp and student producer Kaya Basatemur are joined by Dr. Corey Roach, a researcher from the University of Pennsylvania, to answer these questions and more.
Lyme Disease, while not particularly deadly, is a highly common disease in the Northeast and upper Midwestern North America. According to the Global Lyme Alliance, roughly 476,000 new cases are reported every year. And although this is a curable disease, many people end up experiencing the characteristics of Lyme Disease long after they have been "cured", leading to chronic symptoms. Today, tune into a conversation between Dr. Jonathan Karp and student producer Kaya Basatemur as they discuss everything you need to know about this disease.
You may have heard about Methylene Blue recently, with many people promoting it as a cure for different ailments and diseases, and possibly as a "cognitive enhancer". But what is methylene blue and how does it work? Is it really helping to alleviate all these illnesses? Listen in on a conversation between Dr. Jonathan Karp and student producer Kaya Basatemur as they go into the science of this prospective medication. From the history to the health benefits and risks, this is Methylene Blue.
The words "Food Safety" can mean a wide range of things- whether or not to wear gloves in food preparation, what temperature to store and cook food at, how to avoid cross-contamination, and even where your food is coming from. With so many things to be mindful about when preparing or eating food, Dr. Jonathan Karp and student producer Kaya Basatemur clear up some myths and misunderstandings regarding food safety and provide some history on what has happened when these precautions aren't taken.
From ice baths to cold showers to polar plunges, Dr. Jonathan Karp and student producer Kaya Basatemur discuss the health benefits and drawbacks of cold water immersion. Can dunking yourself in a freezing bath raise your immunity? Does it lower anxiety and reduce stress levels? Find out the answers to these questions and more in the latest episode of Health 411.
What is a phobia, and is it a bad thing to have one? Are there treatments for phobias? Today, Dr. Jonathan Karp and student producer Kaya Basatemur talk about these questions as they discuss phobias from a social perspective to a neurobiological perspective.
What's the difference between an EMT and a paramedic? Today Dr. Jonathan Karp and student producer Kaya Basatemur are joined by Wayne Murphy, a paramedic for Capital Health with over thirty years of experience, to have a conversation about what being an EMT or a paramedic is about.
Are there different kinds of empathy? What makes someone empathetic towards another person? Today Dr. Jonathan Karp and student producer Kaya Basatemur discuss what empathy is on a neurobiological level.
J.D. Barker: White Russian (2 ounces vodka, 1 ounce Kahlua, 1 ounce heavy cream)J.D. talks about how he stalked and then connected with Stephen King, how his partnership with James Patterson has changed his writing method, the way he has turned his Asperger Syndrome into his secret weapon for writing novels, the landmark publishing imprint of his own within Simon & Schuster and how he worked with CEO Jonathan Karp and the private equity firm KKR to establish the business model for it, the pros and cons of independent publishing and traditional publishing, the remote island that is the setting for his latest ‘Chiller' novel as well as is the setting for his real life.
Is vaping bad for you? How do you become an interventional pulmonology specialist? Today Dr. Jonathan Karp and student producer Kaya Basatemur are joined by Dr. Diana Kolman, one of Capital Health's Interventional Pulmonologists.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB discuss celiac disease, an autoimmune disease that causes the body to attack itself when gluten is ingested.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB discuss H5N1, the trending bird flu virus that has had great implications on economics.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Dan Geller discuss a dyslexia, a learning disability affecting 5-10% of people in the United States!
On this episode of Health 411, host Dr. Jonathan Karp and student producer chat with Dr. Mona Saleh, Gynecologic Oncologist at Capital Health.
On this episode of Health 411, host Dr. Jonathan Karp and Student Producer Marina JB are joined by Rafael Villalobos, Legal Counsel for Capital Health!
On this episode of Health 411, host Dr. Jonathan Karp and student producer are joined by Neurologist Dr. Materese from Capital Health in a conversation about concussion care.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Dan Geller raise awareness for non-alcoholic fatty liver disease!
On this episode of Health 411, host Dr. Jonathan Karp and student producer Dan Geller discuss the brain circuit associated with substance use issues.
In this week's episode, host Dr. Jonathan Karp and producer Daniel Geller welcome Dr. Emil Matarese, a highly regarded neurologist and the Director of the Concussion Program at Capital Health. During the conversation, Dr. Matarese provides insight into his background and experience as a neurologist, as well as the work being done through the Concussion Program to treat and prevent this common injury. Listeners will gain valuable knowledge on the causes and treatments of concussions from an expert in the field.
In this episode of Health411, host Dr. Jonathan Karp and producer Daniel Geller discuss the fascinating topic of head transplantation. They explore the feasibility and controversy surrounding the idea of transplanting a human head onto a different body. The scientific and ethical implications of this complex procedure are discussed, including the work of Sergio Canavero, a neurosurgeon who has been at the forefront of head transplantation research. Join us for an insightful and thought-provoking discussion that will challenge your views on what is possible in modern medicine. Tune in to this episode of Health411 and gain a better understanding of the possibilities and limitations of head transplantation.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB discuss a recent study concerning handwriting and the neural connections associated with learning!
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB jump into conversation about astrocytes and inflammatory pain!
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB Are joined by Anna Delaney, the Forensic Anthropologist at the NJ State Police Crime Lab.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB Are joined by Dr. Riggs, professor of Immunology at Rider University!
On this episode of Health 411, host Dr. Jonathan Karp and Student Producer Marina JB are joined by Elizabeth Iozzino, the current Diabetes Quality Coordinator at Capital Health.
On this episode host Dr. Jonathan Karp is joined by Ked Ziora, co founder of Estenda Solutions.
On this episode of Health 411, host Dr. Jonathan Karp and Student Producer Marina JB talk about a recent study affecting different pain pathways in Redheads.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB discuss the neurobiology of depression, and a new study that may help to predict depression before symptoms occur.
On this episode of Health 411, host Dr. Jonathan Karp and Student Producer Marina JB are joined by Dietitian Amy Focht in a captivating discussion about disordered eating.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Jonathan Hunt Glassman, CEO and co-founder of Oar Health, a telemedicine company that helps those with substance use disorders recover with naltrexone.
On this episode of Health 411, host Dr. Jonathan Karp and student producer discuss the potential connection between autism and the gut microbiome.
On this episode of Health 411, Neuro-Oncologist Dr. Mike Salacz joins host Dr. Jonathan Karp and student producer Marina JB in an engaging conversation about the ups and downs of working with brain and spinal cord tumors.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Erin Shehan MS, LCGC who works currently as a Clinical Cancer Genetic Counselor at Capital Health.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Rebecca Kelly, Director of Strategic Partnerships at Capital Health.
On this episode of Heath 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Rebecca Kelly, Director of Strategic Partnerships at Capital Health
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Rider University's Dietitian, Amy Focht. Tune in as we bust some common diet myths!
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Alexandra Nelson, Divisional Director of Child and Maternal Health Services at Capital Health.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Professor of Biology and Behavioral Neuroscience at Rider University, Dr. Riggs. Tune in to learn about monoclonal antibodies, an important component of many medications and diagnostic processes!
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB discuss a medication that has been trending on social media - Ozempic!
On this episode of Health 411 host Dr. Jonathan Karp and student producer Dan Geller talk about the origin of consciousness. Tune in to this fun conversation about the technicality of the brain and what science knows about why we are the way we are!
On this episode of Health 411, host Dr. Jonathan Karp and student producer Josh Brewer discuss the causes and effects of nausea and vomiting.
On this episode of Health 411, host Dr. Jonathan Karp is joined by student producer Daniel Geller are joined by Dr. Bonilla, who focuses on Oncology and Hematology.
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Landon Hacker and Ashley Schaefer from the Camden Coalition. Tune in to hear about how bringing law and healthcare together can better serve patients dealing with use disorders!
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Victoria Pena-Cardinali, LCSW from Capital Health.
On this episode of Health 411, host Dr. Jonathan Karp and student producers Marina and Josh talk about the benefits, misconceptions and the science behind acupuncture.
Simon & Schuster is not growing old quietly.The venerable publishing house — one of the industry's so-called Big 5 — is celebrating its 100th birthday this month after a period of tumult that saw it put up for sale by its previous owner, pursued by its rival Penguin Random House in an acquisition bid that fell apart after the Justice Department won an antitrust suit, then bought for $1.62 billion last fall by the private equity firm KKR.With conditions seemingly stabilized since then, the company is turning 100 at an auspicious time to celebrate its roots and look to its future. On this week's episode, Gilbert is joined by Simon & Schuster's publisher and chief executive, Jonathan Karp, to talk about the centennial and what it means.“It was a startup 100 years ago,” Karp says. “It was two guys in their 20s. Richard Simon and Max Schuster. They were just a couple of guys who loved books. And they made a decision that they wanted to read every book they published. … The first book was a crossword puzzle book. It was a monster success. They'd actually raised $50,000 from their friends and family. They didn't need it. They returned the money. And the company was up and running.”We would love to hear your thoughts about this episode, and about the Book Review's podcast in general. You can send them to books@nytimes.com.
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