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Guyom tracklist : 1 - Jocelyn Brown - I'm Caught Up (In a One Night Affair) (John Morales remix) 2 - Pockets - Work It Out (Dave Lee redemption mix) 3 - Unlimited Touch & Louie Vega - I Hear The Music In The Streets (touch mix) 4 - John Morales & Thommy Davis feat Richard Richard Burton - Was That All It Was (John Morales next day remix) 5 - Michael The Lion feat Amy Douglas - Get In On (Bosq remix) 6 - Bobby & Steve feat Gwen Yvette - Let's Go All The Way (disco mix) 7 - Anané - Tell Me That I'm Dreaming (Dave Lee remix) 8 - LCGC feat Annette Bowen - Rather Be (Ayce remix) 9 - Qwestlife feat Teni Tinks - Hit It Off (Late Nite Tuff Guy remix) 10 - Donna Allen - Joy & Pain (Dr Packer remix) 11 - Paul Johnson - Better Than This (Director's Cut remix) 12 - Tensnake - Coma Cat 13 - Ben Westbeech - Falling 14 - Franck Roger - You're The One For Me
Send us a textHello, passionate cruisers! This is Paul and welcome to The Joy of Cruising Podcast, and in this special episode we meet members of the World-Renowned London Community Gospel Choir (LCGC) and discuss their participation in this summer's Caribbean Gospel Choir Workshop Cruise on the stunning new MSC World America. I am delighted to welcome the founder of LCGC, Bazil Meade; Kaylin Cain, who is coordinating the Caribbean Gospel Choir Workshop Cruise, and long-time member of LCGC, Jenny La Touche.LCGC is one of the most energetic and inspiring forces in the UK's music scene, made up of an eclectic mix of people from diverse backgrounds, embodying their message of God's love, peace and unity in a refreshing and invigorating style of Gospel. With a tight-knit ensemble of talented vocalists, they share joy, and feel-good music with all their audiences. They are proud to represent the metropolitan community of London, coming together as a tight-knit ensemble of talented vocalists, sharing joy, and feel-good music with their audiences.They have worked with over 100 artists around the world in their 40 plus years and were the first Community Gospel Choir in Europe. They have sung live and recorded with various artists around the world including Elton John, Madonna, Paul McCartney, Stevie Wonder, Luther Vandross and Mariah Carey. This is their first time performing and holding workshops in the Caribbean on an amazing cruise ship!Caribbean Gospel Choir Workshop Cruise: For The Love Of Music Events Limited will present this Caribbean cruise which begins on August the 30th when you set sail from Miami aboard the new Luxury Cruise Ship, MSC World America.7-night cruise features:· Full board dining including Premium Drinks Package· Pre-paid gratuities, all taxes and supplements· Workshops led by specialist workshop leaders· Performance and LCGC Concert onboard the ship which includes the Gospel Workshop Choir made up from guestsRelying on ship wifi is slow, unsecure, sometimes not available & at foreign ports travelers don't want to pay their carriers' high fees. Save $ with GigSky! Get a data package usable on the ship & in ports. Link to GigSky: https://gigsky.pxf.io/nloxor. For a 10% discount use code: joyofcruisingSupport the showSupport thejoyofcruisingpodcast https://www.buzzsprout.com/2113608/supporters/newSupport Me https://www.buymeacoffee.com/drpaulthContact Me https://www.thejoyofcruising.net/contact-me.htmlBook Cruises http://www.thejoyofvacation.com/US Orders (coupon code joyofcruisingpodcast)The Joy of Cruising https://bit.ly/TheJoyOfCruisingCruising Interrupted https://bit.ly/CruisingInterruptedThe Joy of Cruising Again https://bit.ly/TheJoyOfCruisingAgainIntl Orders via Amazon
**The Happy Sound of Universe, 60 minutes Full Happy 01 mark knight & mark dedross - fighting love 02 mirko & meex - dreamer 03 yuichi inoue - a night in the room 04 the thompson project - messin with my mind 05 michael gray - over you 06 dexter troy - a slice of funk 07 daniel dash - disco stuff 08 da lukas - doin me wrong 09 LCGC & annette bowen - rather be 10 ny's finest - stand up for your love 11 soulmagic - get your thing together 12 andrea tomei - get down
RADIO PROGRAM ISSUED LIVE, RECORDED IN VIP BOILER STUDIO, AND WILL BE BROADCASTED INTEGRALLY FROM RADIO ABRERA FM (BARCELONA) MIXED BY JOHN C. BRAVE, BARCELONA ON SATURDAY, MARCH 1, 2025 - HOUSE, NU-DISCO, SOULFUL HOUSE, DEEP HOUSE, JACKIN HOUSE, TRIBAL HOUSE, PROGRESSIVE HOUSE & TECH-HOUSE. EVERYTHING MIXED WITH RELOOP RP-8000-MK2 PLATES, TIME CODE VINYLS, PIONEER DDJ-1000SRT. LONG LIFE AT THE HOUSE MUSIC. ENCOURAGE AND ENJOY THE SESSION !!! ¡¡¡¡¡¡¡¡¡¡¡¡PROMOTIONAL USE ONLY !!!!!!!!!!!!! 1) LCGC, Annette Bowen - Rather Be (Richard Earnshaw Remix) 2) Moby, Anfisa Letyago - You & Me (KC Lights Extended Remix) 3) Juiceppe - Finally (Original Mix) 4) Mother Funkerz - Motel Sunshine (Extended Mix) 5) LCGC, Annette Bowen - Rather Be (Richard Earnshaw Remix) 6) Moby, Anfisa Letyago - You & Me (KC Lights Extended Remix) 7) LCGC, Annette Bowen - Rather Be (Richard Earnshaw Remix) 8) Juiceppe - Finally (Original Mix) 9) Mother Funkerz - Motel Sunshine (Extended Mix) 10) GhostMasters - Shady Luv (Extended Mix) 11) Southlight - Gonna Raise Me Up (Extended Mix) 12) Revival House Project, Kathy Brown - Dance To The Music (David Penn Remix Extended) 13) Maurizio Basilotta - Jacked Disco 04 (Original Mix) 14) Manybeat - Disco Venezuela (Original Mix) 15) GhostMasters - Call Me BigPoppa (Club Mix) 16) Disco Gurls - Your Life's A Mistery (Club Mix) 17) Nelly Furtado - Say It Right 2025 (Pedro Cazanova Club Mix) 18) Ertan Koculu - Narcos (Extended Mix) 19) Laurent Simeca - Be With Me (Original Mix) 20) Olive F - Hot Sauce (Extended Mix) 21) Tommy Mambretti - Stronger (Original Mix) 22) Rebeka Brown, Deux - Sun Rising Up (David Penn Original Remastered Edit) 23) DJ Vartan, Techcrasher - Assasin In The Club (Original Mix) 24) Stevie Nicks - Stand Back (Martial Simon Remix) (Martial Simon Extendend Remix)
Close Counters - Feeling Takes Over Me,Eric Redd - Where There's Life (Club Mix), Chaka Khan - I'm Every Woman (Whoopie Edit),LCGC, Annette Bowen - Rather Be (Richard Earnshaw Remix),Young Pulse, Fleur De Mur - Love Addict, Diplomats of Soul feat. Incognito and Vanessa Haynes - Sweet Power (Terry Hunter and Emmaculate Remix) Louie Vega - The World Is A Family (Salsa Radio Edit),Sabrina Malheiros - Estação Verão (Kenny Dope Remix),Charles Petersohn - Children of Zu Zu,The Matsiko World Orphan Choir - Rise (Black Sonic and Sean Mccabe Extended Mix), Phyllis Hyman - Forever With You (from LP 'One More Chance'),Bam feat. Martha Wash - You're Gone (David Harness Mix),Close Counters - Waterfall, The Invisible Session - I'll Be Your Wings (The M&D Mix),Vladimir Cetkar - More Than I Ever Asked For,Dexter Wansel - Life On Mars,Gladys Knight & The Pips - How Deep Is Your Love (from LP 'One More Chance' LP),The Dells - Make Sure (You Have Someone Who Loves You), Willie Hutch - Just Another Day,Luther - Don't Wanna Be A Fool,Magic Lady - Betcha Can't Lose, Harvey Ross - Shine Your Light (Radio Edit),Change - Sunrise Forever (Michael Gray Remix),
The Music Box returns to Starpoint Radio. Join me alternate Sundays between 12-2pm GMT at www.starpointradio.com for some great soulful music across the styles and tempo's.......as we like to do on The Music Box!!Jenn Em - I'm Ready (US Death Row Records/Gamma MP3 LP “Death Row Revue” 2025)The Doggett Brothers feat. Coco Malone – Falling (UK Doggett Brothers Music Promo MP3 – forthcoming 2025)Change feat. Tanya Michelle Smith - Sunrise Forever (Radio Version) (EU Just Entertainment MP3 2025)David Morales & Emiliano Pepe - You Don't Love Me (Original Mix) (US DIRIDIM Promo MP3 – forthcoming 2025)The Soultrend Orchestra & Filippo Perbellini – Borderline (EU Irma Records MP3 LP “Now Imagine” 2025)Tristan – Changes (EU Isolde Records Promo MP3 – forthcoming 2025)Mike Champion - I Got You (AUS Young Boy Sound MP3 2024)Rony Breaker feat. Chinua Hawk - Solid Ground (Brian Tappert For The Heads Remix) (EU Dafia Records MP3 2025)Yooks & Ed Ramsey - It's You (Original Mix) (UK Infinity Music Recordings MP3 2025)DJ Spen pres. Guri Guri Boys feat. Aaron K Gray - Fiyah (Masaki Morii Remix) (US Quantize Recordings MP3 2025)Papik pres. The Soultrend Orchestra feat. Wendy D. Lewis - Wiser (Jay Caruso Extended Remix) (EU Irma Records MP3 2024)Nathan Haines feat. Marlena Shaw - Squire For Hire (Fouk Remix) (UK Foliage Records MP3 2025)Babs Presents - Over & Over (Instrumental) (UK Bumpin' Underground Records MP3 2025)Rita Satch - Meet Me In The Garden (Radio Edit) (AUS Silk Throne Records MP3 - forthcoming 2025)Teri Tobin & Al Chauncy - This Life With You (US Sol 2 Kep Ent. Promo MP3 2025)Charlie Bereal - Wife Soul (US Death Row Records/Gamma MP3 LP “Death Row Revue” 2025)The 7:45's feat. Martin Connor - The Way That I Love You (UK LRK Records Promo MP3 2025)The Paradise Projex - Magic Night (UK Expansion Records Promo MP3 – forthcoming 2025)Velvet Funk - Golden Hour Groove (EU Andrea Reggiana MP3 2024)S-Tone Inc. feat. Laura Fedele – Candlelight (EU Edizioni Ishtar/Schema Records MP3 2025)Al Chestnut - Keep Shinin' Your Light (US Abdul Entertainment Music Group, LLC Promo MP3 2025)LCGC feat. Annette Bowen - Rather Be (Richard Earnshaw Remix) (UK Papa Records Promo MP3 – forthcoming 2025)DJ Spen pres. Jaemus, Sen-Sei & Becka feat. Jeff Straw - The Rain Has Stopped (DJ Spen Remix) (US Quantize Recordings MP3 2025)Ed Ramsey - Save Our World (Richard Earnshaw Classic Extended Mix) (US Category One Music MP3 2025)Prefix One feat. Nambi - Grateful (Glenn Underground Cosmic Disco LoFi Journey Mix) (UK Househead London Promo MP3 – forthcoming 2025)Trinidadian Deep - I Didn't Wanna Lie To You (Original Mix) (UK Makin' Moves MP3 “Jump Up & Move EP” 2024)Enjoy!Mark
Dr. Andrew Nish is joined by Isabella Holland, MS, LCGC, and Caroline Williams, MS, LCGC, who are both genetic counselors at John Stoddard Cancer Center! They dive into what genetic counseling is and the rapid changes that are happening in the world of genetic testing.
Réécoutez FG Chic Mix avec Romain Villeroy du samedi 30 novembre 2024 Tracklist : Disco Incorporated - Roots (Feeling Dub)Sergio D'Angelo, Aldo Bergamasco - Can You Feel My LoveBarry&Gibbs - Let Her Dance (Original Mix)Pete Heller - Big Love (The Dronez Mix)Romain Villeroy - Keep Moving (Original Mix)Adri Block - Under Your Spell.wavLCGC feat. Annette Bowen – Rather Be (Ayce Remix)Shabi - Jirokichi Jazz (Original Mix)Fred Kingdom, Michael Gray - Lost in the Rhythm (Michael Gray Extended House Mix)D.P.V. - Gotta Keep OnSeamus Haji, Stephen Granville, Moplen - Race Of Survival (Moplen Extended Remix)FormulaK, Tess Leah - I Pray (Earth n Days Extended Remix)FrescoEdits - Freedom (Extended Mix)
Recorded on Sunday 24 November 2024. Tracklist 1. Lynda Dawn - Altogether (Reprise) feat. Marco Bernardis 2. K15 - Escape 3. Opolopo & Angela Johnson - In The Meadows 4. SAULT - Son Shine 5. Boreal Sun - code 6. K15 - Measured Resistance 7. Stefano De Santis - Tokyo 80' 8. LCGC feat. Annette Bowen - Rather Be (Ayce Instrumental Remix) 9. LCGC feat. Annette Bowen - Rather Be (Ayce Remix) 10. Unlimited Touch - I Hear Music In The Streets (François Kervorkian Mix) 11. Dias Quentes - The Return (3AMstrumental) 12. Dias Quentes -The Return (Sunset Mix) 13. Janet Jackson - NTNP (Wez Whynt Edit) 14. Josh Milan feat. Jumaane Smith - Wayne Shorter's Infant Eyes (Honeycomb Instrumental) 15. Josh Milan feat. Jumaane Smith - Wayne Shorter's Infant Eyes (Honeycomb Beats) 16. Jullian Gomes & Kuniyuki Takahashi - Let Me Go feat. Sio (Atjazz Astro Remix) 17. Glenn Underground - Jive Assin' 18. Vick Lavender & Angel-A - Rain 19. Pacha - One Kiss (Dave's Heavenly Star Instrumental) 20. Pacha - One Kiss (Dave's Heavenly Star Mix) 21. Dreamer G & Kerri Chandler - I Got That Feelin' (Demuir's Playboi Edit) 22. Masters At Work - MAW TX81Z 23. Those Guys - Tonite (Mark Francis & Merlin Bobb Remix) 24. Estelle - Oh I (Terry Hunter Main Mix) 25. Soul Of Hex - Into The Night 26. Terry Dexter - Renegade (Frankie Feliciano Vocal Mix) 27. Sean McCabe & Black Sonix - Modulate 28. Rob Redford - Lifetime 2 Lifetime (Craig Smith Remix) 29. Timmy Regisford - Not The Blues 30. Lil Louis - Accept Me 31. St. David - Summer Nights Fall
Réécoutez FG Chic Mix Urbana by David Penn du vendredi 8 novembre 2024 Tracklist :1.Stranger Danger & Sen-Sei ft. Becka - Rebound Jazz (Foo Funkers 'Vocal' Remix) - mood funk2.LCGC ft. Annette Bowen - Rather Be (Ayce Remix) - papa3.Purple Disco Machine ft. Lorenz Rhode & Jake Shears - Dirty Pleasures - 4.Jay Vegas - Sunshine People - 5.Angelo Ferreri & Pietro Over Jack - Tube Track - motive6.David Penn & Rober Gaez - Deep Inside (Jay Vegas Remix) - urabana recordings7.Fuzzy Hair - Need It - milk & sugar8.Majestic ft Barbara Tucker - My Love For You - Defected9.Wh0 - Big Zipper - golden records10.Earth n Days - The Groove - houseU11.Emily Nash x Robert Flott - Girl in the Club - ministry of sound12.Kings Of Tomorrow ft April Morgan - Fall For You (Hot Since 82 Extended Remix) - defected
The Music Box returns to Starpoint Radio. Join me alternate Sundays between 12-2pm GMT at www.starpointradio.com for some great soulful music across the styles and tempo's.......as we like to do on The Music Box!!Norma Jean Wright - Jumpstreet (Alex Di Ciò Extended Mix) (US RoyDor Music/RFC Promo MP3 – forthcoming 2024)Kim Tibbs - It's Alright! (UK Kim Tibbs MP3 2024)Temesi Berci feat. Debórah Bond - Soul Is The Flavour (HUN BTM&E Kft MP3 2024)Gyratory Allstars - Keep Our Love Alive (UK GA Records MP3 “Gyratory Allstars EP” 2024)Ezra Collective & Olivia Dean - No One's Watching Me (UK Partisan Records MP3 LP “Dance, No One's Watching” 2024)Ashley Henry - Take It Higher (UK Royal Raw Records/naïve MP3 LP “Who We Are” 2024)LCGC feat. Annette Bowen - Rather Be (Ayce Remix Edit) (UK Papa Records Promo MP3 – forthcoming 2024)Soul Magic & Ebony Soul feat. Ann Nesby - Get Your Thing Together (Jonny Montana & Yorkee 2025 Remix) (US Bassline Records Promo MP3 2024)Seb Skalski & Rona Ray - It's Getting Started (House Extended Mix) (US Nervous Records MP3 2024)Bobby & Steve feat. Overjoyd - Welcome To The Real World (Cafe 432 Bump Remix) (UK Groove Odyssey Records MP3 2024)DJ Spen pres. Paris Cesvette & Hannah Khemoh - Love The Way (US Quantize Recordings Promo MP3 LP “As Above, So Below” 2024)Melchyor A - My Mind (Melchyor A's Gambler Version) (UK Makin' Moves MP3 2024)Stefanie Bolton - Solid Rock (US Sillybo Music MP3 2024)T.J. Wilkins - That's Alright (US Lyric House MP3 LP “Yesterday, Today, Forever” 2024)Michael Kiwanuka - The Rest Of Me (UK Universal Music Operations MP3 LP “Small Changes” 2024)Tuxedo - Think Twice (US Funk On Sight MP3 LP “Tuxedo IV” 2024)MJ Soul - Taking Back My Love (UK MJ Soul MP3 2024)Raquel Rodriguez - Don't Forget (US Raquel Rodriguez MP3 LP “Housewife” 2024)Nicolay feat. Sy Smith - A Thousand Miles (US The Foreign Exchange Music MP3 LP “Terra Firma” 2024)AC Soul Symphony - Soul Underground (UK Z Records MP3 2024)Melchyor A - Everyday (Melchyor A's Afrojazz Version) (EU RazanaProd Records MP3 2024)Glenn Underground - Jive Assin' (Dub Edit) (US Strictly Jaz Unit Muzic MP3 2024)Brutha Basil - Move (Soulful Mix) (US Brukel Music MP3 2024)Stefano De Santis – Roy (EU Quattro Bambole Music Promo MP3 “New Beginning EP” – forthcoming 2024)Enjoy!Mark
Carla Prather - Good With It (Richard Earnshaw Extended Mix),David Morales - Be Somebody (Kenny Carpenter Extended Vocal Mix),Wipe The Needle - The Way (The Journey Men Vocal Remix),AC Soul Symphony - I Want To See You Dance (Art Of Tones Edit),The Shapeshifters - Lola's Theme Recut (Dr Packer Remix),808 Beach x Amy Douglas - Whatever Daddy Says (John Carr "J-C" Extended Glitter Mix),Ernesto and The Basement Gospel - Is It True? (Atjazz Remix),Atjazz and Shea Soul - Home (Emmaculate Remix),Kevin Yost - Get In Your Mind (Original Mix),Paris Cesvette - Love The Way (feat. Hannah Khemoh),Tony Walk - Turn Your Love Around (DJ Pope Funkhut Remix),Ken Walker - Lovely Day (Night Mix),Shaila Prospere and Terri Green - Gonna Get Over You,Viveen - Should Have Been You,Juan Laya/Jorge Montiel - You Can't Beat It,LCGC feat. Annette Bowen - Rather Be (Ayce Remix Edit),Chocolateclay - Free (I'll Always Be),William DeVaughn - Something's Been Done,Xxception To The Rule - The Sweeter The Juice,Tuxedo - Think Twice,The Intrepids - After You've Had Your Fling,Candi Staton - I Can't Stop Being Your Fool,The Valentinos - I've Got Love For You,Candi Staton - You Bet Your Sweet, Sweet Love,David A Tobin - Go Back And Make It Right,Kenny Thomas - Stay (Sassy Soul Mix),
Urbana Radio Show By David Penn Chapter #663 01. Stranger Danger & Sen-Sei ft. Becka - Rebound Jazz (Foo Funkers 'Vocal' Remix) - Mood Funk 02. LCGC ft. Annette Bowen - Rather Be (Ayce Remix) - Papa 03. Purple Disco Machine ft. Lorenz Rhode & Jake Shears - Dirty Pleasures 04. Jay Vegas - Sunshine People 05. Angelo Ferreri & Pietro Over Jack - Tube Track - Motive 06. David Penn & Rober Gaez - Deep Inside (Jay Vegas Remix) - Urbana Recordings 07. Fuzzy Hair - Need It - Milk & Sugar 08. Majestic ft. Barbara Tucker - My Love For You - Defected 09. Wh0 - Big Zipper - Golden Records 10. Earth n Days - The Groove - HouseU 11. Emily Nash x Robert Flott - Girl in the Club - Ministry Of Sound 12. Kings Of Tomorrow ft. April Morgan - Fall For You (Hot Since 82 Extended Remix) - Defected Thanks to all the labels and artist for their music. All tracks selected and mixed by David Penn DJDAVIDPENN.COM FACEBOOK DJDAVIDPENN INSTAGRAM @DJDAVIDPENN INGENIUM BOKINGS EUROPA MUSIC MANAGEMENT Encoded by MUSICZONE PODCAST SERVICES.
As broadcast @ www.totallywiredradio.com Tuesday 22.10.24Hour One and Two with Ket Shah01. Cissy Houston - Don't Wonder Why (Janus /Major Minor 1970)02. Jono McCleery - So Messed Up (Sonar Kollektiv 2024)03. Los Yesterdays - Name On Me (Now Again 2024)04. Scrimshire -Willow (Alberts Favorites 2024)05. Candidates Of Ebba - Hjertet Går Sin Vej (Music For Dreams 2024)06. Les Hommes - Sonorissima Bay (Sudden Hunger 2024)07. Omar Wilson - The Bad One's (BSE 2024)08. BJ The Chicago Kid ft Ledisi & Philip Bailey - Never Change (RTW / RCA / Sony 2024)09. Summer Pearl - The Creator (Kitto 2024)10. The Smoothies - Alone On My Birthday (The Soul Sanctuary 2024)11. Ezra Collective - N29 (Partisan 2024)12. Mackwood - Dog (5db 2024)13. Chocolateclay - Free (I'll Always Be) (Cat / RCA / Soul Jazz 1977 /2024)14. Lynda Dawn - Where You Are (First Dawn 2024)15. Thee Marloes - I Know (Big Crown 2024)16. William Devaughn - Something's Been Done (Chelsea 1974 / 2024)17. Zé Nigro ft. Fernanda Broggi - Calor (NuBlu 2024)18. Nicolay - Maybe Tomorrow (The Foreign Exchange 2024)19. Nubiyan Twist - Battle Isn't Over (Strut 2023/2024)20. HNQO - Grizzly Gett (Apparel 2024)21. Stefan Ringer - Cleanse (Black Acre 2024)22. Ed Temple ft Lyma & Elf - On My Mind (Inkswel Remix) (Temple Musiq 2024)23. Private Joy - Let Love Find A Way (Rhythm Section 2024)24. Beats y Bateria - Moldovan Disco (Stolen Mask 2024)25. LCGC ft. Annette Bowen - Rather Be (Ayce Instrumental Remix) (Papa 2024)26. Girls of the Internet ft i Am An Island - Sleeping Sound (Classic Music Company 2024)27. Carla Prather - Good with It (Richard Earnshaw Extended Mix) (Category One 2024)28. Paris Cesvette & Will Downing - You Are Magic (Quantize 2024)29. David Morales & Romina Johnson - Be Somebody (Kenny Carpenter Extended Vocal Mix) (Diridim 2024)
David Morales - Be Somebody (Original Mix),Donnie, Kai Alce - Love (4 Letter Word) (NDATL Vocal Mix),Bobby and Steve - Welcome To The Real World (Pat Bedeau Bedfunk Vocal Mix),Groove Junkies, Reelsoul - Cold, Cold World,Antonio Ocasio, Ed Ramsey - Going To The Mountain,Husky feat. Rona Raye - Hold Me (Art Of Tones Remix),Tommy Glasses - Time,Gianni Bini/Anduze - Ain't Nothing Going On(Micky More/Andy Tee Extended Remix),Daisy Hicks - Electric Love (Alex Di Ciò Mix),Norma Jean Wright - Jumpstreet,LCGC feat. Annette Bowen - Rather Be (Ayce Remix Edit),Bobby Harden and The Soulful Saints - Feels So Good,Elijah Baker Presents Park Avenue - I Never Had It So Good,Enchantment - Sunshine,The Stylistics - Searchin',Gregory Porter - Faith In Love,Nicola Conte - Do You Feel Like I Feel (feat. Gregory Porter),Kim Tibbs - Believe In Something Called Love,Jessie Laine Powell - Make Me A Believer,Lenny White - Who Do You Love (feat. Chaka Khan),Jalen Ngonda - Illusions,Thee Sacred Souls - Running Away,Ernest Ernie and The Sincerities - She Won't Come Calling,Otis Leavill - You Babe (instr.),
On this episode of Health 411, host Dr. Jonathan Karp and student producer Marina JB are joined by Erin Shehan MS, LCGC who works currently as a Clinical Cancer Genetic Counselor at Capital Health.
Expert Approach to Hereditary Gastrointestinal Cancers presented by CGA-IGC
This new podcast series, initiated by the CGA-IGC Research Committee in 2023, highlights the work of previous CGA-IGC Research Grant recipients. The second episode is hosted by Catie Neumann, MS., LCGC, a Cancer Genetic Counselor at Fox Chase Cancer Center, and features the 2022 grant recipient, Giovana Torrezan, PhD, an associate researcher at A.C. Camargo Cancer Center in Sao Paulo, Brazil.The podcast transcript is available here.
Children's genetic disorders and the non-profit Cool Cars for Kids were discussed by Sarah E. Raible, MS, LCGC, a genetic counselor and the clinical director of the Center for Cornelia de Lange Syndrome (CdLS), and rare disease core leader in the Roberts Individualized Medical Genetics Center (IMGC) at Children's Hospital of Philadelphia and the Chief Operating Officer of Cool Cars for Kids, and Lainey Moseley, an Emmy® award winning journalist working for CBS and NBC News, founder of CHOPS Syndrome Global; an organization raising awareness for her daughter Leta's rare disease CHOPS Syndrome, and Cool Cars for Kids Board Member. We talked about how ‘rare' is rare? One in 11 families are affected by some form of genetic disorder, ranging from clef lip, spina bifida, to heart malformations and other identifiable conditions. Othe genetic mutations can be so rare that – as in the case of Leta, the exact cause can take decades to discover. Her disorder was identified by a CHOP test when she was 18, her genetic condition named CHOPS Syndrome in honor of the hospital that discovered it. Today there are some 40 patients found in Italy, Texas and around the globe, now connected by Lainey's organization. We spoke about the extra roles the parents of these children must take on, caregiver, advocate and researcher. Lainey is currently in post-production on her documentary RARE, an essay-style documentary in three acts, each delving into the lives of families grappling with rare diseases, the immense challenges they face, and the remarkable scientific progress they drive in the quest for cures. She has also organized their 2nd CHOPS Syndrome symposium in Philadelphia this summer, July 19th and 20th where Unravel Bioscience will be discussing their results for potential FDA repurposed drugs that may be treatment options for their kids. Fundraising is vital to these families and to the research that helps identify their conditions. Cool Cars for Kids was founded by former CHOP geneticist Ian Krantz , Sarah and others to provide help and hope to children with rare genetic diagnoses and their families, and to support research that will identify the best possible treatments and cures. Their annual fundraiser, the Seventh Annual Philadelphia Concours d'Elegance kicks off with a Preview Gala on Saturday, June 22, followed by the main event on Sunday, June 23 at the Simeone Foundation Automotive Museum. Tis year's featured model is the Jaguar, with special displays and a panel discussion about the vehicle. There will again be the Cool Car Corral, an outdoor space where anyone can display their ‘cool' car, classic, rare or just beloved. Kids activities, music, food trucks and admission to the Simeon racing car collection are part of the day's fun. Tickets and corral registration available by visiting philadelphiaconcours.com or coolcarsforkids.org. Walk-ins and drive-ins are welcome that day.
Germline and somatic testing for in prostate cancer can improve outcomes and promote early detection and prevention, yet many patients are not aware of testing and the impact it can have on treatment options. In this episode, CANCER BUZZ speaks with David Gill, MD, medical oncologist at Intermountain Healthcare's Intermountain Cancer Center and Lindsey Byrne, MS, LCGC, licensed certified genetic counselor at The Ohio State University Comprehensive Cancer Center, who discuss how genetic counselors and increased patient education can help cancer programs close the practice gap and promote guideline-concordant testing among patients diagnosed with prostate cancer. “I'd really advocate—even in your patients with a negative NGS panel—please still consider getting germline testing in those patients.” –David Gill, MD “We know that individuals, yes, they're dealing with a diagnosis of cancer, but the first thing people say to me when I sit down with them is, ‘All right, I have this figured out, but what does this mean for my family?' They're really worried about their family, and that's where our focus is, to help take care of that.”—Lindsey Byrne, MS, LCGC David Gill, MD Medical Oncologist Intermountain Healthcare - Intermountain Cancer Center Salt Lake City, Utah Lindsey Byrne, MS, LCGC Licensed Certified Genetic Counselor The Ohio State University Comprehensive Cancer Center – The James Columbus, Ohio This episode was developed in connection with the ACCC education program Germline and Somatic Testing for Mutations to Optimize Outcomes in Metastatic Prostate Cancer and is supported by AstraZeneca, Johnson & Johnson, and Pfizer. Resources: Germline and Somatic Testing for Mutations to Optimize Outcomes in Metastatic Prostate Cancer - ACCC Abstract: Homologous recombination repair gene mutation (HRRm) testing patterns and treatment selection from a real-world cohort of patients with metastatic castration-resistant prostate cancer (mCRPC) Abstract: Utilization of genetic counseling and testing for patients with prostate cancer following integration of a genetic counselor into a genitourinary cancer clinic
We are joined by Petr Vozka, Assistant Professor of Chemistry at California State University, Los Angeles where he leads the Complex Chemical Composition Analysis Lab. Prof. Vozka completed his PhD work at Purdue University, where he also spent time doing post-doctoral research. At Purdue, he first encountered LECO's separation sciences equipment and progressed his research to Cal State LA as a faculty member in 2020. His research is centered around non-targeted analyses of a wide range of complex mixtures including fuels, products from plastic waste depolymerization, fingerprints, and oil spills. This year, LCGC recognized Prof. Vozka as a Rising Star in Separation Sciences and LECO launched a new laboratory in partnership with Cal State LA with several different pieces of LECO equipment. Links: 2024 Multidimensional Chromatography Workshop: http://www.multidimensionalchromatography.com/ Petr Vozka's Complex Chemical Composition Analysis Lab: https://www.calstatela.edu/research/c3al LECO Separation Science: https://www.leco.com/separation-science
ASCO: You're listening to a podcast from Cancer.Net. This cancer information website is produced by the American Society of Clinical Oncology, known as ASCO, the voice of the world's oncology professionals. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guests' statements on this podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Cancer research discussed in this podcast is ongoing, so data described here may change as research progresses. In this podcast, Dr. Allison Kurian and genetic counselor Kristen Mahoney Shannon talk about what people should know about genetic testing and hereditary breast cancer, including what to expect when meeting with a genetic counselor, ways to reduce your risk of developing cancer, and talking about genetic test results with family. Dr. Kurian is a Professor of Medicine and of Epidemiology and Population Health at Stanford University School of Medicine, and Director of the Stanford Women's Clinical Cancer Genetics Program. She is also the 2023 Cancer.Net Specialty Editor for Breast Cancer. Ms. Shannon is a senior genetic counselor and Director of the Cancer Center Genetics Program and Director of Genetic Counseling for the Massachusetts General Hospital Department of Medicine. She is also a 2023 Cancer.Net Advisory Panelist. View disclosures for Dr. Kurian and Ms. Shannon at Cancer.Net. Dr. Allison Kurian: I'm Allison Kurian. I am a professor of medicine, oncology, and epidemiology and population health at Stanford University. And I am speaking today with my colleague, Kristen Shannon, who will introduce herself. Kristen Shannon: Hi, it's great to be here. My name is Kristen Shannon. I am a genetic counselor and the director of cancer genetics at Massachusetts General Hospital in Boston. And I have no financial relevant disclosures to report. Dr. Allison Kurian: Thank you, and I have no relevant financial disclosures either. Very good. So today we will be talking about breast cancer and inherited risk and genetic testing. And let me start by providing a definition of a genetic or hereditary condition. So the way we think about this is something that has a high risk for developing a disease, not a certainty, but a high risk, and runs in families, generally because of a genetic finding that we can identify. And that typically is identified through sequencing, testing of blood or saliva samples, and typically allows us to find a change that we know is clearly associated with disease. A good example for breast cancer are the genes BRCA1 and BRCA2, which some may have heard of, and we will talk about further. So that is just an example, and we will get into more of the details of this as we go on. But I think the point is something that runs in families often is seen with the trait, so for BRCA1 or BRCA2, that would be breast cancer or ovarian cancer, affecting people in every generation. And having what we call for these kinds of genes an autosomal dominant inheritance pattern, so inherited from either parent. And taking only 1 copy that is not functioning to give a person higher risk of the condition. So that's sort of a bit of the basics here on genetic or hereditary risk. And just to give a sense of how common hereditary breast cancer is, we think that in general this may account for, I would say, somewhere between 5% to perhaps 10% of cases of breast cancer. And Kristen, please jump in and tell me if you think differently. But that would be my ballpark. And I think probably the majority of those are the BRCA1 and BRCA2 genes that I mentioned, although there are others that we are recognizing are playing more of a role than we thought, and we'll discuss those, too. So let me give you a chance to continue and respond, Kristen. Kristen Shannon: Yeah, no, I totally agree. And I was thinking that maybe I could talk a little bit about some of the features that are suggestive that there could be one of these inherited breast cancers in the family, because recognizing these signs of hereditary breast cancer can be super important for early detection and prevention of breast cancer. So first, multiple cases of breast cancer within the family, especially among close relatives like parents, siblings, children, those can be a sign that the cancer is inherited. Another important sign is early age of onset of disease. So breast cancer diagnosed at a young age, typically before the age of 50, might point towards hereditary risk. And it's not always the case, but it's something to be aware of. Also, if there is a history of ovarian cancer in the family, especially if you see it in conjunction with breast cancer cases, that's a significant sign that there could be something inherited in the family. And while it's rarer, male breast cancer can also be associated with hereditary gene mutations. So if there's a history of male breast cancer in the family, it's definitely something to think about in terms of hereditary risk. Multiple cancer types in the family can also be another clue. It's not always just breast and ovarian cancer. If you see a family history of both breast and ovarian cancer or pancreatic cancer or prostate cancer within the same family, that also might be a sign of an inherited cancer syndrome. For individuals of Ashkenazi Jewish descent, it's worth noting that they have a higher prevalence of certain gene mutations in specific genes, specifically BRCA1 and BRCA2, which Dr. Kurian has mentioned before. So a family of history of breast or ovarian cancer in an Ashkenazi Jewish individual should be noted as a higher sign that this cancer could be due to an inherited gene. And lastly, if someone has had breast cancer in both breasts, that's called bilateral breast cancer, and that might indicate hereditary risk. It's important, though, to remember that it's not just about any single sign in isolation. You really need to take a look at the bigger picture and the bigger context of the family. So if you notice any of these signs in your family, it's a good idea to seek guidance from a health care professional, like a genetic counselor or a medical oncologist, and they can help assess the family's risk and recommend genetic testing if needed. Dr. Kurian, did I forget anything or leave anything off? Dr. Allison Kurian: Perfect as always. I will just add a little bit here in terms of the specific gene names that we think about, because sometimes it helps people to have sort of a list in their minds, not that we expect you to remember the whole alphabet soup of these different genes. And let me just say that I think it's always a bit of a hodgepodge, some of these names. I used to wonder how people come up with these names, and often there's a bit of a history there. But I will just go through a few of them. We now have some practice guidelines, and they are basically put together by a group of experts who review all the evidence frequently and come up with recommendations. And so there is a list in these guidelines of basically which genes we think are appropriate to test for breast cancer in families, because there's enough evidence to suggest that. And so in addition to BRCA1 and BRCA2, the ones that I think of as the most important, and I'll want to hear Kristen's thoughts about this, too, but the ones that we see most often are called ATM. Sounds like a cash machine, unfortunately not, but ATM. CHEK2, C-H-E-K-2, and then one called PALB2, which stands for Partner and Localizer of BRCA2, and is a lot like BRCA2 in its risks. There are some other genes that give breast cancer risks that are less common. One of them, CDH1, is a gene that also causes an increased risk of stomach cancer. There are a few others that we always keep in mind. There's one called PTEN that's very rare that causes a syndrome called Cowden syndrome that I certainly haven't seen much of. Kristen may have seen more, but it's not something we see often and goes with a lot of other features in families. There are 2 genes that I think we recognize more in recent years and like to be sure we test, called RAD51C and RAD51D, and those both give increased risks. And then another one that I always think of as important here is TP53, and that is a gene that causes something called Li-Fraumeni syndrome, which has probably the highest cancer risks of which we know. There's another one, STK11, that gives some risk, NF1. We see these as being less frequent contributors. Those are the ones that I kind of keep in mind. And again, there will not be a quiz on the alphabet soup, but just so you're aware of what kinds of names you might hear. Kristen, please jump in if I've forgotten any or anything else you want to say. Kristen Shannon: No, I think that that's important. I think the only thing that I would add is that some people think when they go in for breast cancer genetic testing, they only are getting the BRCA1 and BRCA2 gene. And it's just important for people to realize that that's not really a complete test at this point, as you mentioned, Dr. Kurian. Dr. Allison Kurian: Totally agree, and thank you. Kristen Shannon: Should we move into how to prepare for a genetic counseling appointment? Dr. Allison Kurian: Please, yes. Kristen Shannon: Sure, okay. So preparing for a genetic counseling appointment for breast cancer risk can be helpful. First and foremost, we suggest that you gather your family health history. So reach out to your relatives and compile as much information as possible about your family's health background. Pay special attention to any instances of breast cancer and ovarian cancer, prostate cancer, pancreatic cancer in the family. And if any family members have had genetic testing, it's really helpful to jot down those test results as well and bring them with you to the appointment. The other thing is to think about your own personal medical history. You know, think about if you've had any past diagnosis, any treatments, surgeries, or medical conditions, especially those related to breast cancer, your genetic counseling appointment will include a discussion of those. The other thing is, you know, if you've had any medical tests related to cancer, it's important to gather those records if they're not already in your hospital's medical record system that you are going to. Another good idea is to just prepare a list of questions that you might want to have answered. So what do you want to know? Are there specific concerns or specific things you're curious about? It's also important to understand what you want to get out of this genetic counseling encounter. Do you want to just clarify your risk of having a gene? Do you want to consider genetic testing? Or do you want to talk about just managing your risk for breast cancer? That's super important to have that in mind before you actually go into your appointment. Lastly, I would consider bringing along a person, a supportive person with you to the appointment. Having someone with you can help provide emotional support because sometimes these visits can get emotionally charged, but it also can help to have someone remember important details that you will discuss with your health care provider. So it's really important to just arm yourself with information, questions, and support so that the appointment is as productive and informative as it can be. Do you have anything else you'd like to add, Dr. Kurian? Dr. Allison Kurian: It's wonderful to have your expert perspective on this. And I guess any thoughts about really what's inside the box? I think sometimes people just sort of wonder what's going to happen when I go in that room. Sometimes we have patients come in and say, “What are you guys going to do to me? Will there be surgery done?” And we reassure them that we are not doing anything that wild. And so maybe just a sense of kind of walking people through what will happen when they go to meet with genetic counselors. Kristen Shannon: Absolutely, thanks for bringing that up. So during the initial meeting, first you'll probably discuss your personal health history, again, any past diagnoses, surgeries, medical conditions. And then typically a genetic counselor or a medical professional will dive right into your family health history. So they'll ask a whole bunch of questions about your close and extended family members to build a really comprehensive picture of your family and the cancer diagnosis in it. They'll want to know if anyone in your family has had cancer, and they'll also want to know what type of cancer that person has had and also the age at which that person was diagnosed. So those are the 3 pieces of information that your health care provider will want to get from you. The genetic counselor will also probably ask you about what you want to get out of this encounter to make sure that you're both on the same page. Again, do you want genetic testing? You know that already. Or do you want to just talk through the process? So the big part of the initial meeting is really education. The genetic counselor will explain what Dr. Kurian described at the very outset of this discussion, what's the genetic basis of hereditary breast cancer, including all the specific genes that Dr. Kurian—the alphabet soup that we talked about. Talk about inheritance patterns and the implications of having a genetic mutation. The genetic counselor will probably also first assess your risk of having a mutation in one of the genes, and then they'll also talk to you often about genetic testing. So if genetic testing is on the table and you and the genetic counselor both agree that it's a good step, they'll walk you through the process of informed consent. And so this ensures that you understand what the testing entails, the potential outcomes, the implications of the test results. And then if you decide to go through with genetic testing, you will provide a blood or a saliva sample. And then it's a waiting game because these test results can take several weeks, usually about 3 to 4 weeks to get the test results back. When the test results come back, you'll typically have a follow-up appointment, either in-person or on the phone with your genetic counselor. And that's when they spend a lot of time interpreting the test results, explain what they mean for you and your health, as well as discussing the appropriate risk management strategies, if necessary. And if a gene mutation is identified, a genetic counselor will guide you on how to manage these risks. But it will depend on the specific mutation that is identified. And then the other thing that the genetic counselor can help with is just the emotional support. Some people have a harder time than others hearing this information. And also to talk about how to tell your family members about this. So in a nutshell, the initial meeting with the genetic counselor is about gathering information, assessing risk, and potentially deciding on whether or not you're going to have genetic testing. And then after that step, it's about interpreting the test results, talking about next steps, and providing emotional support. Dr. Allison Kurian: Thank you, Kristen. That was wonderful and very complete. And as I was listening to you, first of all, I was thinking about my general admiration for genetic counselors, which is huge. They taught me everything I know about this field. But so also kind of highlighting the key things that a meeting with a genetic counselor will do for you, as you so nicely did. And I think it's getting the right test ordered, making sure that the results make sense to you, and going beyond the patient. But I think those are sort of the key aspects that you communicated really well of the things that we want to get done there. Kristen Shannon: Well said, well said. And I couldn't agree more. Dr. Allison Kurian: And what do you think about the family part in terms of how that gets done? Kristen Shannon: Right, so discussing your genetic test results with family members can be hard and challenging, but it's really, really important. In terms of talking to your family members, I think first, determine the way you're going to notify your family members. So are you going to talk to them? Are you going to send them a letter or an email? And how you share the information may be different based on your relationship with that person. So for example, you may sit down over coffee with a close family member to talk about your test results, but you may choose to write a letter to someone that you don't have that much contact with. The next thing that I think is really important is to be prepared. So before you even start to have this conversation, make sure that you have a clear understanding of your genetic test results, the implications to you and to the family member. That's super important before you even start to have the conversation so that you can explain things to people in simple terms without too much medical jargon and make sure you keep it straightforward. It's really helpful to have a copy of your genetic test results and to provide that to your relatives if you're comfortable doing so, because then they can take that information with them to their genetic counseling or genetic testing appointment, which can be incredibly essential in terms of making sure that they get the correct test at the right time and the test results are interpreted correctly. The only other suggestion I have is just to keep in mind that family members are going to react very differently to this information. And some people will be very matter of fact about it. Some people might get a little distracted by this whole thing. So just to be patient with people and keep the conversation open. Allow them to call you if you're willing to do that so that the conversation can develop over time because, you know, really, in the end, the goal is to make sure that everyone in the family is well informed and makes decisions based on their own health and their well-being. Dr. Allison Kurian: Thank you. I couldn't agree more. And we sometimes, as people may have heard, call this “cascade genetic testing.” So a patient is tested. Somebody who's already had cancer maybe is tested. But then we have the opportunity to have this cascade of beneficial genetic testing, where we can get to people before they have cancer and work on prevention and screening, which I'll talk about in a minute. And I will say that, in general, we here in the United States, and certainly other places as well, don't do as well as we would like with cascade testing despite all best efforts of everyone. And so just to emphasize that family notification is super important, genetic counselors are wonderful at helping people to do that. And I think also additional strategies and interventions are underway to try to help make that easier. So if I may, I'll talk just a little bit about kind of what we do when we find something. Is that okay to do? Kristen Shannon: That sounds great. Talk about people, you know, what they can do about their test results. Dr. Allison Kurian: Good. Yeah, so I always think that's important. I'm an oncologist by training. I'm not a geneticist. And again, it's only thanks to the brilliance of genetic counselors like Kristen that I have learned what I have for the last 2 decades working in the field. But so I tend to think in terms of what can we do to treat this person differently if they have cancer to prevent or reduce the risk of a future cancer. And so what I would say is increasingly over the last few years for a person with breast cancer, as well as some additional cancers, it started to matter what these results are in terms of how we treat the person, whether we might give different medications. And that's really exciting because for years in this field, we didn't have that, and now we do. And so the drugs that are increasingly important are called PARP, P-A-R-P, inhibitors. And sometimes, if a person has a BRCA1 or BRCA2 gene mutation, we might even offer those drugs to treat a breast cancer or, in other cases, ovarian, prostate, or pancreatic cancer. So I think the testing can matter like never before in terms of what we might do to take care of people's cancer. Sometimes we might also choose a different surgery. So sometimes a woman who has a diagnosis of breast cancer might choose to do a more extensive breast surgery, she might choose a double mastectomy to reduce her risk of getting a second breast cancer. That's never required. She certainly doesn't have to do so extensive a surgery if she doesn't choose, but it is an option that some people might choose. And there might also be other cancer risks to manage in somebody who had breast cancer. BRCA1 and BRCA2, for example, give a high risk of ovarian cancer. And so we might talk with someone about the possibility of removing ovaries to prevent an ovarian cancer, which often is recommended with BRCA1, BRCA2, and other such gene mutations. I will say that I think for somebody who hasn't had cancer yet, or hopefully ever, particularly as we think about breast cancer, we're often thinking about intensive screening. So starting often earlier than a person would if she didn't have high risk and generally adding magnetic resonance imaging, MRI, to screening with mammogram alone. And that really is, I think, the cornerstone for women at high risk is adding that breast MRI screening. For pretty much all of the genes I mentioned, that would be clinically indicated and covered by insurance and important to do. MRI has no radiation, very effective at finding breast cancer early. So I think to summarize, it's really all about understanding risk based on a particular gene mutation, understanding if a different kind of treatment is needed for the cancer that a person has, understanding if any sort of preventive measure is needed for future cancer risk, and making sure that the screening we have for breast and for other cancers is appropriate to the level of risk. Anything to add there, Kristen? Kristen Shannon: No. No, I think that that's great. Dr. Allison Kurian: Absolutely. Yeah, so I think it's wonderful to have this opportunity to speak about the importance of genetic testing, which is I think more important than it ever has been at this time for the care of patients with breast cancer and their families. And so as we move into breast cancer awareness month, it's great to be able to talk about this. Thanks so much. Kristen Shannon: Thank you so much. I agree. And if you have any questions, I would suggest you reach out to your doctor or look up on the ASCO website for a referral to a genetic counselor. ASCO: Thank you, Dr. Kurian and Ms. Shannon. Learn more about hereditary breast cancer and genetic testing at www.cancer.net/hboc. Cancer.Net Podcasts feature trusted, timely, and compassionate information for people with cancer, survivors, and their families and loved ones. Subscribe wherever you listen to podcasts for expert information and tips on coping with cancer, recaps of the latest research advances, and thoughtful discussions on cancer care. And check out other ASCO Podcasts to hear the latest interviews and insights from thought leaders, innovators, experts, and pioneers in oncology. Cancer.Net is supported by Conquer Cancer, the ASCO Foundation, which funds lifesaving research for every type of cancer, helping people with cancer everywhere. To help fund Cancer.Net and programs like it, donate at CONQUER.ORG/Donate.
Welcome to “Analytically Speaking,” the podcast from LCGC and Spectroscopy. Here in Episode 15, podcast host Dr. Jerry Workman talks to Dr. Ellen Miseo and Dr. Zac Schultz about the benefits of participating in the Coblentz Society. Ellen has been involved in vibrational spectroscopy and instrument development her entire career and is trained as a physical chemist. She has worked for instrument companies as well as run laboratory operations. She is past president of both the Coblentz Society and Society for Applied Spectroscopy. She currently heads Miseo Consulting. Zachary Schultz is Professor of Chemistry and Biochemistry at The Ohio State University and is the current President of the Coblentz Society. He is widely published on the subject of vibrational spectroscopy and also has an interest in undergraduate science education, and professional development, advancement, and mentoring.
Listen in to this podcast recorded live at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting with Barb Kunz, MS, LCGC!
Welcome to “Analytically Speaking,” the podcast from LCGC and Spectroscopy. Here in Episode 13, podcast host Dr. Jerry Workman talks to Dr. Paul C. DeRose, who is a senior research chemist at the National Institute of Standards and Technology (NIST) and leads the NIST Biochemical Science Division's project in luminescence standards development for chemical analysis and assay validation. We spoke to Paul about his current research interests in fluorescence and luminescence spectroscopy, specifically concerning the development of fluorescence standards and methods for validation of chemical and clinical assays. Paul's research has resulted in publications in various areas of fluorescence spectroscopy and microscopy. He has developed fluorescence standard guidelines and recommendations for ASTM, IUPAC, and the US Pharmacopeia. He is also the chair of ASTM E13.01.01 sub-committee on Molecular Luminescence.
Rick Greene, MD, discusses with Julie Culver, MS, LCGC, CCRP, the implementation of genetic testing for all patients with breast cancer and how this can be incorporated into oncology care. Ms. Culver is author of “Integration of Universal Germline Genetic Testing for All New Breast Cancer Patients.” Julie Culver is the Director of Genetic Counseling at the USC Norris Cancer Hospital and is a Clinical Instructor of Medicine at the USC Keck School of Medicine, Los Angeles, CA. http://doi.org/10.1245/S10434-022-12595-W
If you are one of the listeners that tune into DNA Today every week, then you definitely know by now we have launched our Patreon. This is where you can not only get bonus content from DNA Today, you can get early access to episodes before the public. You also get to influence the content of the show, this includes episode topics and guests plus pitching questions I ask during interviews, and of course I will give you a shoutout when I ask your question. Oh and if you sign up by May 25th you get a bonus physical gift! For these benefits and more you can visit our Patreon, link is in the show notes and on our website DNAToday.com.We are continuing our peek into the past! Last episode we explored the history of the genetic counseling field with Michelle Fox and Debra Collins who shared about the first annual National Society of Genetic Counselors (NSGC) conferences. In this episode we are learning about the formation of the American Board of Genetic Counseling (aka ABGC) with Ann Walker and Ed Kloza. Ann Platt Walker, MA, LCGC has held many leadership positions including the Founding President and Director of the American Board of Genetic Counseling (ABGC), President of the National Society of Genetic Counselors (NSGC) in 1982, and has been on the Board of Directors for the American Board of Medical Genetics (ABMG), American Society of Human Genetics (ASHG), and the American Council for Genetic Counseling (ACGC). During Ann's career she held roles at the University of California, Irvine Medical Center including as the program director for the Master's of Science in Genetic Counseling Program for over two decades. She has authored over 20 peer reviewed publications, 10 book chapters, and countless abstracts and presentations. Ann has been awarded many times through her impressive career including the Natalie Weissberger Paul National Achievement and Leadership Awards from NSGC.Ed Kloza, MS, LCGC was the first genetic counselor in Maine. He helped establish clinical genetics in Southern Maine and pioneered prenatal serum screening at the Foundation for Blood Research in Scarborough, and was a member of the team from Women & Infants Hospital of Rhode Island which published the first international clinical validation study of cell-free DNA screening. He was key in the development of the genetic counseling profession including as a past president of NSGC (the first, and one of only two males elected to that position), and in helping create the American Board of Genetic Counseling (which we are focusing on today). In 2000, Ed was honored with the Natalie Weissberger Paul National Achievement Award. Currently Ed is the genetics education consultant for the New England Regional Genetics Network (NERGN) and is an adjunct Professor at Bay Path University with their graduate Genetic Counseling program.On This Episode We Discuss:The ABGC versus the NSGC and which came first!The early days of board examsWhat prompted the creation of the ABGC in 1992Challenges in forming ABGCThe original goals of ABGC as an organizationThe first ABGC president and other key playersWhen ABGC began to accredit genetic counseling programsEstablishing practice-based competenciesIf you want to learn more about the history of the GC field, check out Episode 136 with Linda Robinson . Episode 31 with Robin Schwartz also gives a great overview of the field. You can learn more about ABGC by heading to their website, or by following them on Twitter, Facebook, and LinkedIn. Stay tuned for the next new episode of DNA Today on May 12th, 2023, where we'll be discussing risk assessment advances for Alzheimer's disease! New episodes are released every Fridays. In the meantime, you can binge over 235 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Episodes since 2021 are also recorded with video which you can watch on our YouTube channel. DNA Today is hosted and produced by Kira Dineen. Our social media lead is Corinne Merlino. Our video lead is Amanda Andreoli. Our Outreach Intern is Sanya Tinaikar. Our Social Media Intern is Kajal Patel. And our Graphic Designer Ashlyn Enokian.See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com. Want to become a genetic counselor? Looking for ways to engage with the field and boost your resume for grad school applications? Then you should check out Sarah Lawrence's “Why Genetic Counseling Wednesday Summer Series”! Every Wednesday this June (plus the last Wednesday in May) Sarah Lawrence is hosting a series where you can interact through Zoom with genetic counselors from different specialties. It kicks off on May 31st! You can sign up at SLC.edu/DNAtoday. Again visit SLC.edu/DNAtoday to register to level up your resume for applications in the fall. (Sponsored)As many of you know through podcasting I have become an entrepreneur including consulting for other podcasts. Since I don't have a business degree I have learned a lot through podcasts like Porch Talks. The inspiration to start this show was from the host Melissa Bradley who wanted to inform, instruct, and inspire fellow entrepreneurs, especially in people who identify as women, people of color, immigrants, veterans, people with disabilities, and folks in the LGBTQIA+ community (which drew me in initially). So if you are thinking about starting a business or just love hearing stories about how businesses grow, Porch Talks is for you. (Sponsored)Surely you have heard of whole genome sequencing, but what about rapid and ultra-rapid whole genome sequencing? This is an emerging method of diagnosing genetic conditions for quick management. PerkinElmer Genomics offers this incredibly valuable test, which can be life saving for ill babies and kids. Learn more in our full episode (#226) with PerkinElmer Genomics. You can visit perkinelmergenomics.com for more information. (Sponsored)
In this episode of The Seam Podcast, we sit down with Angela Arnold Ross, MS, LCGC, Genetic Counselor to discuss inherited gene mutations and their role in cancer risk. Angela brings years of experience and expertise to the conversation, sharing insights into genetic testing and counseling, treatment options, and available resources for patients and their families. She emphasizes the importance of genetic counseling before and after undergoing genetic testing and explains the various options. Angela also sheds light on the multitude of known and unknown genetic mutations and their significance in cancer risk. Tune in to learn from Angela's wealth of knowledge.The SEAMLynne Cohen FoundationGuest: Angela Arnold RossProduction by Peoples Media Hosted on Acast. See acast.com/privacy for more information.
There are a lot of genetic tests out there for those planning a family and those expecting their little one. It can be rather confusing which tests you should get and why. Many families are also concerned about how invasive the tests are and how accurate the tests are, and what they should be doing with their results. To dive into this conversation of prenatal and preconception genetic testing on Yoga| Birth| Babies I have Kira Dineen MS, LCGC, CG(ASCP)CM a certified genetic counselor who has been specializing working with pregnant folks and helping people planning pregnancy to obtain family history and to explore genetic testing options. She's also the host and producer of the podcast DNA Today. Kira helps demystify a lot of the genetic tests out there and how to decide which tests might be best for you and your family. She is incredibly fun. I had such a great time. Even though this can feel like a very heavy topic, the way that Kira explains it and her enthusiasm, will help set you at ease and provide you some clarity around genetic testing during pregnancy and preconception. I know you're going to enjoy this episode. Get the most out of each episode by checking out the show notes with links, resources and other related podcasts at: prenatalyogacenter.com Don't forget to grab your FREE guide, 5 Simple Solutions to the Most Common Pregnancy Pains HERE If you love what you've been listening to, please leave a rating and review! Yoga| Birth|Babies (Apple) or on Spotify! To connect with Deb and the PYC Community: Instagram & Facebook: @prenatalyogacenter Youtube: Prenatal Yoga Center Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to “Analytically Speaking,” the podcast from LCGC and Spectroscopy. Here in Episode 11, podcast host Dr. Jerry Workman talks to Prof. Yukihiro (Yuki) Ozaki, who is a professor emeritus in the School of Science and Technology at Kwansei Gakuin University in Japan. He has been a guest professor or scientist at Kobe University and the Toyota Physical and Chemical Research Institute. We spoke to Prof. Ozaki about his theoretical and advanced applications-oriented studies using near-infrared spectroscopy. Yuki is involved in studies of a wide range of molecular spectroscopy techniques, covering from far-ultraviolet to far-infrared–terahertz spectroscopy and also Raman spectroscopy. He is a rather rare scientist who has carried out research in both electronic and vibrational spectroscopy. Yuki has been a member of the Society for Applied Spectroscopy (SAS) for more than 30 years and a Fellow since 2013. He has received several awards, including the Bomem-Michelson Award (2014), the Chemical Society of Japan Award (2017), the Pittsburgh Spectroscopy Award (2019), and the Charles Mann Award (2020).
Welcome to “Analytically Speaking,” the podcast from LCGC and Spectroscopy. Here in Episode 9, podcast host Jerry Workman speaks to Prof. Rasmus Bro, who is a full professor at the University of Copenhagen and one of the foremost active living data analytics and chemometrics experts. We spoke to Prof. Bro about the world of data analysis used for spectroscopy and other analytical methods. Over the years he has worked on many aspects of chemometrics, developing numerous algorithms and methods such as fuzzy logic, deep learning, analysis of variance, and tensor modeling. He has received multiple awards in chemometrics and in the analytical sciences, and is the second-most-cited scientist within the field of chemometrics with nearly 37,000 citations and an h-index of 78 (Google Scholar). Most of the algorithms and data sets he has worked on have been made publicly available on the internet. We have invited Prof. Bro to our Analytically Speaking podcast to discuss his research on the development and automation of several chemometrics methods for use with any spectroscopic technique.
It Happened To Me: A Rare Disease and Medical Challenges Podcast
Genetic Counselor, and our podcast co-producer, Kira Dineen shares her insight on when to pursue genetic counseling and how genetic counselors can help people in the rare disease community. Co-producer Kira Dineen, MS, LCGC, CG(ASCP)CM has over a decade of podcast experience fueled by a passion for science communication. She has hosted and produced 7 podcasts. Her multi-award winning podcast, "DNA Today", is in the top 1% of podcasts globally. She was accepted into The Podcast Academy and has served as a Blue Ribbon Panelist for The Ambies. Kira received her Diagnostic Genetic Bachelor's of Science degree at the University of Connecticut and is a certified Cytogenetic Technologist. She received her Master's of Science in Human Genetics at Sarah Lawrence College in New York and is a licensed certified genetic counselor currently practicing in Connecticut. On This Episode We Answer: When should a person or couple consider genetic counseling? Is a referral required to see a genetic counselor? Does insurance cover genetic counseling for this? Is genetic testing done before the visit? How many visits are we talking about? Do you ever suggest adoption as an option? When? How do you help people with genetic conditions? Why get tested at all? What have you learned from interviews with patients and rare disease advocates? Do you recommend joining rare disease advocacy groups? Why study rare diseases? What is CRISPR? How could this help treat…or even cure…genetic conditions? You produce a rare disease podcast that focuses on nano rare diseases. What's a nano-rare disease? Stay tuned for the next new episode of It Happened To Me! In the meantime, you can listen to our previous episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “It Happened To Me”. It Happened To Me is created and hosted by Cathy Gildenhorn and Beth Glassman. Steve Holsonback is our media engineer and co-producer. DNA Today's Kira Dineen is our marketing lead and co-producer. Ashlyn Enokian is our graphic designer. See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, ItHappenedToMePod.com. Questions/inquiries can be sent to ItHappenedToMePod@gmail.com.
A new year means a new podcast! We are thrilled to announce that our host, Kira Dineen, is a co-producer of a new rare disease and medical challenges podcast called, It Happened To Me. In celebration of the launch we wanted to share an upcoming episode of the podcast where the hosts Cathy Gildenhorn and Beth Glassman interviewed Kira Dineen. There will also be another episode on the show where they flip roles and Kira interviews Cathy and Beth about their patient advocacy and stories. Hope you enjoy this episode and be sure to subscribe to It Happened To Me in your podcast player. We would really appreciate a rating and review as well on Apple and Spotify. This is KEY for a successful launch! Kira Dineen, MS, LCGC, CG(ASCP)CM has over a decade of podcast experience fueled by a passion for science communication. She has hosted and produced 7 podcasts. Her main show, "DNA Today", is in the top 1% of podcasts globally. Listeners Discover New Advances in the world of genetics through Kira's interviews about genetic technology, disorders, and news. The show won the Best and Science and Medicine Podcast Awards for the last three years, among other awards. “DNA Today” has produced over 215 episodes. Kira is also the host of the PhenoTips Speaker Series, a live webinar interviewing international genetic leaders. Kira produces the Patient Empowerment Program, which is a nano-rare disease podcast. She was selected and served as a member of the National Society of Genetic Counselors' Digital Ambassador program. Kira received her Diagnostic Genetic Bachelor's of Science degree at the University of Connecticut and is a certified Cytogenetic Technologist. She received her Master's of Science in Human Genetics at Sarah Lawrence College in New York and is a licensed certified genetic counselor currently practicing in Stamford, CT. On This Episode We Answer:When should people consider genetic counseling?Do you need a referral?Does insurance pay for genetic testing and counseling?Is genetic testing done before or after the visit? How many visits are typically involved for genetic counseling?What reproductive options do couples have?How do genetic counselors help people with genetic conditions?Why are the advantages of having genetic testing? What have you learned from interviews with patients and rare disease advocates?Do you recommend joining rare disease advocacy groups? Which ones?Why study rare diseases?What is CRISPR? How could this help with treatment of even cures of genetic conditions? What are nano-rare diseases?For more information check out the National Organization of Rare Disorders's Rare Disease Fact sheet. Stay tuned for the next new episode of DNA Today on January 20th! New episodes are released every Fridays. In the meantime, you can binge over 220 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Episodes since 2021 are also recorded with video which you can watch on our YouTube channel. DNA Today is hosted and produced by Kira Dineen. Our social media lead is Corinne Merlino. Our video lead is Amanda Andreoli. Our outreach Intern is Sanya Tinaikar. Our Social Media Intern is Kajal Patel. And our Graphic Designer Ashlyn Enokian.See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com. As a listener of DNA Today, you probably heard me talk about NIPT, non-invasive prenatal screening, that looks for extra or missing chromosome conditions during pregnancy. But did you know there is one that can also screen for recessive disorders (like cystic fibrosis) and fetal antigens? BillionToOne offers UNITY Screen, which does all this from one blood draw from a pregnant person. Visit unityscreen.com for more info. And stay tuned for our upcoming episodes with BillionToOne exploring non-invasive prenatal screening for recessive conditions and red blood cell fetal antigens (Sponsored)If you've been listening to DNA Today for a while, you probably know I am also a full time prenatal genetic counselor. Between that job, this podcast, and being a producer/host of other podcasts, I am pretty busy! To keep my energy up and stay productive I drink a decent amount of coffee. The new coffee I'm drinking is from Four Sigmatic. I'm really picky about my coffee, it's got to be bold, not watery. And I've been really happy with Four Sigmatic. Here's the difference from other coffees, it includes mushrooms, which I know sounds bizarre. I will admit I was hesitant, but you get health benefits and don't taste it. I like the immune system boost, as I often get sick in the winter months. So we teamed up with Four SIgmatic to get you 30% off using promo code “DNATODAY” redeem it at FourSigmatic.com, again that's FourSigmatic.com using code “DNATODAY” for 30% off! And let me know if you like it too! (Sponsored)
It Happened To Me: A Rare Disease and Medical Challenges Podcast
o-host Cathy Zacks Gildenhorn has devoted much of her life to improving the lives of others and connecting women to Jewish life and each other. She has served on several local, national and international boards. Cathy also served as presidential appointee to the United States Holocaust Memorial Council and worked on the opening of the museum. Currently, Cathy serves as editor in chief and designated spokesperson for the book, Redefining Moments: End of Life Stories for Better Living. Several years ago Cathy was diagnosed with a rare, genetic disease. Since then she has passionately dedicated her life to creating this supportive and inspiring podcast so that all in the medically challenged community know…You are Not Alone. Co-host Beth Ourisman Glassman is a third-generation Washingtonian with a deep interest in health care. She is a trustee of the Sibley Memorial Hospital Foundation in Washington and co-chair of A Woman's Journey for the National Capital Area, the 27-year-old women's health program established by Johns Hopkins Medicine. Beth is passionate about empowering women to make the best health care decisions for themselves and their families. Having experienced health challenges herself, she believes that the power of connection and sharing one's own story is instrumental to the healing process. As co-host of the podcast “It Happened to Me,” she shares her ordeals, interviews guests who have experienced similar struggles, and reveals how to overcome and cope with some of the most difficult health challenges. Co-producer Kira Dineen, MS, LCGC, CG(ASCP)CM has over a decade of podcast experience fueled by a passion for science communication. She has hosted and produced 7 podcasts. Her multi-award winning podcast, "DNA Today", is in the top 1% of podcasts globally. She was accepted into The Podcast Academy and has served as a Blue Ribbon Panelist for The Ambies. Kira received her Diagnostic Genetic Bachelor's of Science degree at the University of Connecticut and is a certified Cytogenetic Technologist. She received her Master's of Science in Human Genetics at Sarah Lawrence College in New York and is a licensed certified genetic counselor currently practicing in Connecticut. On This Episode We Discuss: Idea of launching a podcast Motivation behind IHTM Choosing “It Happened To Me” Podcast title Inviting Beth to join as co-host Beth and Cathy's rare diseases Future interviews/topics on upcoming episodes Stay tuned for the next new episode of It Happened To Me! In the meantime, you can listen to our previous episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “It Happened To Me”. It Happened To Me is created and hosted by Cathy Gildenhorn and Beth Glassman. Steve Holsonback is our media engineer and co-producer. DNA Today's Kira Dineen is our marketing lead and co-producer. Ashlyn Enokian is our graphic designer. See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, ItHappenedToMePod.com. Questions/inquiries can be sent to ItHappenedToMePod@gmail.com.
Genetic sequencing is one of the most rapidly growing areas of diagnostic medicine with uses in primary prevention and surveillance planning across cancers, cardiovascular disease, and more. The session will focus on how to utilize clinical genetic screening and testing as a modality to provide evidence-based, patient-centered care in the ambulatory care setting.Speakers:Jennifer Posey, MD, PhD, Assistant Professor, Department of Molecular & Human Genetics at Baylor College of MedicineJill Tapper, MHA, CG (ASCP), System Director, Precision MedicineHitashi Bansal, MS, LCGC, Cancer Genetic Counselor at Virginia Mason Franciscan Health
Kira Dineen, MS, LCGC, CG(ASCP)CM, has a decade of podcast experience fueled by a passion for science communication. She has hosted and produced 6 podcasts. Her main show, "DNA Today", is in the top 1% of podcasts globally. Listeners Discover New Advances in the world of genetics through Kira's interviews about genetic technology, disorders, and news. The show won the Best 2020 and 2021 Science and Medicine Podcast Awards. "DNA Today" has produced nearly 200 episodes. In our conversation, we talk about Kira's journey to genetics, genetic counselling, and what we can and can't learn from DNA testing kits. Show Notes: https://steampoweredshow.com/shows/kira-dineen [00:01:27] Kira's affinity for the field of genetics. [00:04:19] Where Kira saw herself in the field. [00:04:52] Labs are not the only career path in genetics. [00:07:11] The value of shadowing. [00:08:11] Hear from or speak to people in the field and ask questions. [00:08:52] We need a career speed-dating service. [00:10:03] What is genetic counselling? [00:13:42] When would you start the process of speaking with a genetic counsellor? [00:16:41] The two general categories of genetic conditions. [00:21:15] How Direct-to-Consumer DNA testing kits work. [00:24:14] Individual hotspots vs polygenic risk scores. [00:26:46] Our understanding will become more refined as we gather more data. [00:30:04] Kira's podcasting journey. [00:36:26] Podcasting opens doors and creates connection. [00:39:53] Why science communication is important to Kira. [00:46:39] Bonus Question 1: What hobby or interest do you have that is least related to your field of work? [00:47:30] Bonus Question 2: Which childhood book holds the strongest memories for you? [00:48:47] Bonus Question 3: What advice would you give someone who wants to do what you do? And what advice should they ignore? Connect with STEAM Powered: Website | YouTube | Facebook | Instagram | Twitter | Patreon | Ko-Fi
Join Podcast Subcommittee member Mary Pat Bland in conversation with Marci Schwartz, ScM, CGC; Kelly Tangney, MS, LCGC; and Amy Curry Sturm, MS, CGC. This episode covers Marci, Amy, and team's article on the Journal of Genetic Counseling (JoGC) entitled "Genetic Counseling for patients with positive genomic screening results: Considerations for when the genetic test comes first" and is eligible for CEUs as part of the JoGC CEU program. Speakers discuss their work with the myCode Genomic Screening and Couseling Program and the All of Us Research Program. The National Institutes of Health All of Us Research Program is partnering with one million or more people across the United States to build the most diverse biomedical data resource of its kind, to help accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us. Genomic research results from All of Us will be made available to participants who consent to receive them, and those participants will have free, unlimited access to genetic counseling services through Color, who was awarded the All of Us Research Program's Genetic Counseling Resource.
Suzuki Indonesia (yang mobil ya) baru saja meluncurkan mobil citycar terbarunya dengan nama S Presso (kayak nama kopi ya) yang digadang-gadang sebagai SUV kompak namun dengan harga cukup ekonomis. Bagaimana kami menanggapinya? --- Send in a voice message: https://anchor.fm/gibahotomotif/message
Welcome to “Analytically Speaking,” the new podcast from LCGC and Spectroscopy. Here in Episode 3, podcast host Jerry Workman talks to talks to Prof. Karl Booksh of the Department of Chemistry and Biochemistry at the University of Delaware, Newark, who is an expert in Raman and Raman imaging, LIBS, fluorescence, portable chemical sensors, miniaturization of analytical devices, and data driven science incorporating many chemometrics and data analytics techniques. He discusses a National Science Foundation workshop he is organizing with Prof. Barry Lavine entitled, “Data-Driven Measurements and Instruments for Chemistry.” We spoke to Prof. Karl Booksh about his organizing an NSF workshop to explore research on the development of portable chemical sensors for environmental, biomedical, and industrial process monitoring. Karl's own research is predicated on the belief that it is better to build small chemical sensors capable of reliable measurements in the field or in the process than to collect samples for future laboratory analysis. References and Further Reading: Karl Booksh faculty page: https://www.chem.udel.edu/people/full-list-searchable/kbooksh K.S. Booksh and B.R. Kowalski, Theory of analytical chemistry. Analytical Chemistry 66(15), 782A–791A (1994). https://doi.org/10.1021/ac00087a001 D.M. Wilson, S. Hoyt, J. Janata, K. Booksh, and L. Obando, Chemical sensors for portable, handheld field instruments. IEEE sensors journal 1(4), 256–274 (2001). https://doi.org/10.1109/7361.983465 D.M Wilson, S. Garrod, S. Hoyt, S. McKennoch, K.S. and Booksh, Array optimization and preprocessing techniques for chemical sensing microsystems. Sensors Update 10(1), 77–106 (2002). https://doi.org/10.1002/1616-8984(200201)10:13.0.CO;2-F J.P. Smith, E.C. Holahan, F.C. Smith, V. Marrero, and K.S. Booksh, A novel multivariate curve resolution-alternating least squares (MCR-ALS) methodology for application in hyperspectral Raman imaging analysis. Analyst 144(18), 5425–5438 (2019). https://doi.org/10.1039/C9AN00787C C.P. Celani, C.A. Lancaster, J.A. Jordan, E.O. Espinoza, and K.S. Booksh, Assessing utility of handheld laser induced breakdown spectroscopy as a means of Dalbergia speciation. Analyst 144(17), 5117–5126 (2019). https://doi.org/10.1039/C9AN00984A Connect with us on social media: • LCGC LinkedIn page: www.linkedin.com/company/lcgc/ • LCGC on Twitter: twitter.com/LC_GC • LCGC on Facebook: www.facebook.com/lcgcmagazine • Spectroscopy LinkedIn page: www.linkedin.com/company/spectroscopy-media/ • Spectroscopy on Twitter: twitter.com/SpectroscopyMag • Spectroscopy on Facebook: www.facebook.com/SpectroscopyMagazine Subscribe to LCGC or Spectroscopy magazine or our newsletters. • www.chromatographyonline.com/view/subscriptions • www.spectroscopyonline.com/view/subscriptions Email us at LCGCedit@mmhgroup.com. To advertise on the show, contact Ed Fantuzzi at efantuzzi@MJHlifesciences.com
In this episode, podcast host Dr. Dwight Stoll talks with Dr. Katelynn Perrault, an Associate Professor of Forensic Science and Chemistry at Chaminade university in Honolulu, about her pathway to separation science, her research on the composition of odors from decomposing remains, and her thoughts about what the separation science community can do to get more women involved in the field. Drs. Stoll and Perrault talk about multi-dimensional gas chromatography (GCxGC)— which is Perrault's primary research tool—ranging from where the technique stands today, to where progress will likely occur in the near future, and why the technique is so well suited to the analysis of decomposition odors. Useful Links • Kate Perrault's website : https://chaminade.edu/nsm/nsm-faculty/katelynn-perrault/ • Conference website for the 14th Multi-Dimensional Chromatography Workshop, which will be held in Liege, Belgium, at the end of January, 2023 http://www.multidimensionalchromatography.com/ • Kate's post on women in separation science in the LCGC blog: https://www.chromatographyonline.com/view/the-lcgc-blog-she-separates-the-female-voices-of-separation-science Recent Literature Discussed: • K. Raninen, R. Nenonen, E. Reijonen, K. Poutanen, H. Mykkänen, O. Raatikainen, Comprehensive Two-Dimensional Gas Chromatography-Mass Spectrometry Analysis of Exhaled Breath Compounds After Whole Grain Diets. Molecules 26(9), 2667 (2021). https://doi.org/10.3390/molecules26092667. • M. Markowska, A. Krajewski, D. Maciejewska, H. Jelen, M. Kaczmarek, E. Stachowska, Qualitative Analysis of Surgical Smoke Produced During Burn Operations. Burns 46(6), 1356-1364 (2020). https://doi.org/10.1016/j.burns.2020.02.014. • F. Schleich, D. Zanella, P. Stefanuto, K. Bessonov, A. Smolinska, J. Dallinga, M. Henket, V. Paulus, F. Guissard, S. Graff, C. Moermans, E. Wouters, K. Van Steen, F. van Schooten, J. Focant, R. Louis, Exhaled Volatile Organic Compounds Are Able to Discriminate between Neutrophilic and Eosinophilic Asthma. American Journal of Respiratory and Critical Care Medicine 200(4) 444-453 (2018). https://doi.org/10.1164/rccm.201811-2210OC. Connect with us on social media: • LCGC LinkedIn page: https://www.linkedin.com/company/lcgc/ • LCGC on Twitter: https://twitter.com/LC_GC • LCGC on Facebook: https://www.facebook.com/lcgcmagazine • Spectroscopy LinkedIn page: https://www.linkedin.com/company/spectroscopy-media/ • Spectroscopy on Twitter: https://twitter.com/SpectroscopyMag • Spectroscopy on Facebook: https://www.facebook.com/SpectroscopyMagazine Subscribe to LCGC or Spectroscopy magazine or our newsletters. https://www.chromatographyonline.com/view/subscriptions https://www.spectroscopyonline.com/view/subscriptions Email us at LCGCedit@mmhgroup.com. To advertise on the show, contact Ed Fantuzzi at efantuzzi@MJHlifesciences.com
Welcome to “Analytically Speaking,” the new podcast from LCGC and Spectroscopy. Here in Episode #1, podcast host Jerry Workman talks to Prof. Barry Lavine of the Department of Chemistry at Oklahoma State University. Prof. Lavine and his research group have been working on new approaches and algorithms for identification and classification of samples measured using infrared (IR) imaging microscopy in forensic analysis. He discusses aspects of sampling, spectra collection, image generation, and data analysis for infrared imaging and sample identification. Data analytics topics include alternate least squares (ALS) reconstruction of the IR spectra of the individual layers from automotive paint samples using machine learning techniques, spectral database searching, and special experimental design methods. References and Further Reading: Barry Lavine faculty page: https://chemistry.okstate.edu/bios/356-faculty-member-bio-lavine F. Kwofie, N.U.D Perera, K.S. Dahal, G.P. Affadu-Danful, K. Nishikida, and B.K. Lavine, Transmission Infrared Microscopy and Machine Learning Applied to the Forensic Examination of Original Automotive Paint. Applied Spectroscopy 76(1), 118–131 (2022). https://doi.org/10.1177/00037028211057574 B.K. Lavine, A. Fasasi, N. Mirjankar, K. Nishikida, and J. Campbell, Simulation of attenuated total reflection infrared absorbance spectra: applications to automotive clear coat forensic analysis. Applied Spectroscopy 68(5), 608–615 (2014). https://doi.org/10.1366/13-07266 A. Fasasi, N. Mirjankar, R.I. Stoian, C. White, M. Allen, M.P. Sandercock, and B.K. Lavine, Pattern recognition-assisted infrared library searching of automotive clear coats. Applied Spectroscopy 69(1), 84–94 (2015). https://doi.org/10.1177/0003702816666287 B.K. Lavine, K. Nuguru, N. Mirjankar, and J. Workman, Pattern recognition assisted infrared library searching. Applied Spectroscopy 66(8), 917–925 (2012). https://doi.org/10.1366/11-06576 Subscribe to LCGC or Spectroscopy magazine or our newsletters. https://www.chromatographyonline.com/view/subscriptions https://www.spectroscopyonline.com/view/subscriptions Connect with us on social media: • LCGC LinkedIn page: www.linkedin.com/company/lcgc/ • LCGC on Twitter: twitter.com/LC_GC • LCGC on Facebook: www.facebook.com/lcgcmagazine • Spectroscopy LinkedIn page: www.linkedin.com/company/spectroscopy-media/ • Spectroscopy on Twitter: twitter.com/SpectroscopyMag • Spectroscopy on Facebook: www.facebook.com/SpectroscopyMagazine Subscribe to LCGC or Spectroscopy magazine or our newsletters. www.chromatographyonline.com/view/subscriptions www.spectroscopyonline.com/view/subscriptions Email us at LCGCedit@mmhgroup.com. To advertise on the show, contact Ed Fantuzzi at efantuzzi@MJHlifesciences.com
NSGC Podcast Subcommittee members Ryan Kuehl, Liann Jimmons, and Jessica Dronen discuss the implications for healthcare systems and the role of genetic counselors in an evolving newborn screening landscape with Dr. Debra Lynn Day-Salvatore, MD, PhD, FAAP, FACMG; Amy Gaviiglio, MS, CGC; and Laiken Peterson, MS, LCGC. This episode discusses the Journal of Genetic Counseling (JoGC) article "A qualitative assessment of parental experiences with false-positive newborn screening for Krabbe disease" and is part of the JoGC CEU program.
Welcome to “Analytically Speaking,” the new podcast from LCGC and Spectroscopy. In this preview (episode 0), Laura Bush talks with the two people who will share duties as the hosts of the new podcast: • Dr. Dwight Stoll, a professor of chemistry at Gustavus Adolphus College in St. Peter, Minnesota, and • Dr. Jerry Workman, a spectroscopist, noted author, and the Senior Technical Editor of Spectroscopy and LCGC. In this preview episode, we introduce Dwight and Jerry and learn what you can expect from our new podcast. More about our hosts: Dwight Stoll, PhD: Dwight R. Stoll is a professor of chemistry at Gustavus Adolphus College in St. Peter, Minnesota. He received his PhD from the University of Minnesota, under Professor Peter Carr, working on the development of fast, comprehensive two-dimensional liquid chromatography (2D-LC). Stoll's current primary research focus is on the development of 2D-LC for both targeted and untargeted analyses. Active research projects in his laboratory touch on most aspects of multidimensional separation methodologies, including optimization strategies, characterization of selectivity in reversed-phase LC, instrument development, and applications in biopharmaceutical analysis. Stoll is the author or co-author of more than 80 peer-reviewed publications and six book chapters and has instructed numerous short courses in 2D-LC. In 2011 he was the recipient of LCGC's Emerging Leader in Chromatography Award. In 2017 he received the Georges Guiochon Faculty Fellowship, and was recognized with an Agilent Technologies Thought Leader Award. He is also a member of LCGC's editorial advisory board and is the editor of the “LC Troubleshooting” column in LCGC. Jerome Workman, Jr., PhD: Jerome (Jerry) J. Workman, Jr. is the Senior Technical Editor for LCGC and Spectroscopy. He has held positions as CTO, executive VP, senior research fellow, director, and senior scientist at companies of all sizes, from start-ups to world-leading corporations. He has been an adjunct faculty member of four universities and advised multiple graduate students. He has more than 75 U.S. and international patent applications and 30 issued U.S. and international patents and multiple trade secrets, as well as 500+ technical publications, and 20 reference book volumes on a broad range of spectroscopy and data processing techniques. He has received multiple awards from scientific societies, and has taught annual courses in spectroscopy, chemometrics, and statistics for the AOAC, ACS, ISA, FACSS, and at several universities and corporations. He is a Fellow of the American Institute of Chemists (FAIC), the American Society for Testing and Materials (ASTM), and the Royal Society of Chemistry in the UK (FRSC, CChem, CSci). Jerry holds B.A and M.A degrees from Saint Mary's University of Minnesota, and a PhD degree from Columbia Pacific University working in near-infrared spectroscopy. He is an alumnus of both Columbia University Business School and the MIT Sloan School of Management. Subscribe to LCGC or Spectroscopy magazine or our newsletters. www.chromatographyonline.com/view/subscriptions www.spectroscopyonline.com/view/subscriptions Email us at LCGCedit@mmhgroup.com. To advertise on the show, contact Ed Fantuzzi at efantuzzi@MJHlifesciences.com. To advertise on the show, contact Ed Fantuzzi at efantuzzi@MJHlifesciences.com.
Episode kali ini akan membahas tentang Mobil Rakyat yang memuat Local Content 80% dan harganya hingga 250 Juta. Apakah ini memang mobil rakyat ? apa bedanya dengan Mobil LCGC ? Yuk Dengarkan info selengkapnya bersama Bebin Djuana ( Pengamat Otomotif) dalam Podcast Klinik Otomotif Sonora episode kali ini. Acara Klinik Otomotif Sonora juga On Air di Sonora Network Setiap Hari Sabtu, Pk. 10.00-12.00 WIB Streaming: linktr.ee/SONORAFM92.0_JAKARTA
Kira Dineen, MS, LCGC, CG(ASCP)CM, has a decade of podcast experience fueled by a passion for science communication. She has hosted and produced 5 podcasts. Her main show, "DNA Today", is a genetics podcast in the top 1.5% of podcasts globally. The show won the Best 2020 and 2021 Science and Medicine Podcast Awards. Over the last 10 years, the podcast has produced over 165 episodes with 250,000+ downloads. As a licensed certified genetic counselor, Kira Dineen meets with patients who are pregnant or planning pregnancies to obtain family health history and explore genetic testing options. Kira is also certified as a Cytogenetic Technologist and has worked in laboratories performing karyotypes and FISH on constitutional and cancer samples. Kira's Award winning Science & Medicine Podcast: http://dnapodcast.com/ Link Mentioned: https://www.nytimes.com/2022/01/01/upshot/pregnancy-birth-genetic-testing.html Books: http://rebeccaskloot.com/the-immortal-life/ https://www.simonandschuster.com/books/The-Code-Breaker/Walter-Isaacson/9781982115852 Kira's Henrietta Lacks' Episode - https://dnapodcast.com/episodes/2015/9/28/34-henrietta-lacks.html Kira's Special Episodes: http://dnapodcast.com/episodes/2020/9/4/130-dtc-series-anne-greb-on-23andme http://dnapodcast.com/episodes/2021/6/18/150-euan-ashley-and-stephen-quake-on-the-genome-odyssey Correction of misstatement made regarding cost of Henrietta Lacks' cells (I thought 40k, I was mistaken and apologize for the oversight): "Today, Skloot says, a vial of HeLa cells can be purchased online for about $250 a vial." https://www.npr.org/2010/12/13/132030076/henrietta-lacks-immortal-cells-live-on-in-labs "Hela cells and cells with modifications can sell for between $400 and thousands of dollars per vial. Thermo Fisher Scientific estimates its annual revenue at approximately 35 billion dollars a year." https://www.everydayhealth.com/public-health/the-estate-of-henrietta-lacks-sues-biotech-company-for-selling-stolen-cells/#:~:text=Hela%20cells%20and%20cells%20with,35%20billion%20dollars%20a%20year. --- Support this podcast: https://podcasters.spotify.com/pod/show/isitjustspeculation/support
After discussing how genetic testing has evolved, Stephen Daiger, PhD, Director of the Laboratory for Molecular Diagnosis of Inherited Eye Diseases at the University of Texas at Houston, and Emily Place, MS, LCGC, a genetic counselor from Boston's Massachusetts Eye and Ear, talk about the process of interpreting the results of a genetic test—and how empowering it can be for the person, their family, and their future. Learn more from Stephen Daiger on the importance of genetic testing at EyeWant2Know.com.
Track List: (Intro) So much 2 say -Take 6 I appreciate you -Rachel Mcfarlane This is the gospel of Jesus Christ - Hezekiah Walker and LFCC Cast all your cares - The Clark sister There's no greater love - Helen Baylor You can always come home - Commissioned Put a little love in your heart - Mary Mary All I dream of (Heaven) -Divine It's not magic -LCGC
To kick off SEASON 3, we're sitting down with Kira Dineen, MS, LCGC, CG(ASCP)CM! Kira is a licensed, certified prenatal genetic counselor AND the host of the award-winning podcast, DNA Today. Kira and her team won the Best 2020 Science and Medicine Podcast Award, and she's here to tell us all about genetic counseling, what your at-home genetic testing kit may have gotten wrong, and where this exciting field is heading in the future! Send us an email at: malpracticepodcast@gmail.comFollow us on Instagram, Facebook, and Twitter: @malpracticepodcastIf you want to help us grow, subscribe and leave us a review on Apple Podcasts, Spotify, Stitcher, or wherever you get your podcast fix!Sources for this episode:http://dnapodcast.com/ https://twitter.com/kiradineen?lang=enhttps://www.maternalfetalcarepc.com/genetic-counselingSupport the show (https://www.buymeacoffee.com/malpractice)
This episode is an edited recording of the clubhouse meeting Kira Dineen and Dena Goldberg (Dena DNA) hosted on August 26th, 2021 in the “Genetic Counseling and the Future of Healthcare”. We explore making the most of the genetic counseling graduate school experience. Since this was recorded on Clubhouse, the audio is not as high quality as our other episodes. Preparing for a career in genetic counseling? Check out Keck Graduate Institute in Claremont, California! At KGI, you will gain the training and development to become an innovative, collaborative, and caring genetic counselor. KGI prepares graduates to be leaders among healthcare professionals dedicated to the delivery of advanced personally-optimized patient care and the translation of applied and clinical science breakthroughs to enhance the quality of life. So if you want to be a genetic counselor, check out KGI at kgi.edu/dnatoday. Again that's kgi.edu/dnatoday. Hosts:Kira Dineen, MS, LCGC, CG(ASCP)CM is a licensed certified prenatal genetic counselor at Maternal Fetal Care, PC in Connecticut. Kira also has 10 years of online media experience in digital marketing and podcasting/radio including 5 podcasts. She started her main show “DNA Today: A Genetics Podcast” in 2012 which became a radio show in 2014. The podcast has since produced over 150 episodes interviewing experts in the field. “DNA Today” won the People's Choice Podcast Awards for the Best 2020 Science and Medicine Podcast. Kira is also the host of the PhenoTips Speaker Series, a live webinar interviewing genetic experts attended by over 700 genetic counselors around the globe. She writes a monthly blog series, “Explained By A Genetic Counsellor” for Sano Genetics. She received her Diagnostic Genetic Bachelor's of Science degree at the University of Connecticut and is a certified Cytogenetic Technologist. Kira received her Master's of Science in Human Genetics at Sarah Lawrence College in New York. Dena Goldberg Linder, MS, CGC (DenaDNA) is a licensed and board certified genetic counselor. She attended the University of Illinois in Champaign-Urbana for her undergraduate studies where she worked in a Molecular Anthropology lab studying ancestry genetics. Dena graduated from the Genetic Counseling Graduate program at UC Irvine. She worked at the UCSF Cancer Genetics and Prevention Program for four years as the Gordon and Betty Moore Endowed Counselor of Hereditary GI Cancer Prevention. Dena recently left this full time role to pursue Dena DNA and sees patients through Genome Medical. Stay tuned for another episode of DNA Today with Dena in October! Featured Panelist: Rachel Mills, MS, CGC, is a certified genetic counselor and Assistant Professor with the University of North Carolina Greensboro Genetic Counseling Program. She serves as the Research & Capstone Coordinator for the Program and supports students completing their Capstone projects. Prior to joining the UNCG faculty, she spent 10 years working as a research coordinator and project manager on studies exploring the utilization of genomics in healthcare. Much of her work focused on implementation of pharmacogenomics (how genes impact our response to medications).Janelle Villiers MS, CGC is the Admissions Director and Assistant Program Director for Sarah Lawrence College Human Genetics' program. Prior to coming to Sarah Lawrence College, she worked in the clinical setting as a clinical supervisor at Jacobi Medical Center and later worked in a laboratory setting at the Mt. Sinai Genetics Testing Laboratory. She is currently a volunteer site visitor for the Accreditation Council for Genetic Counseling (ACGC).Katie Lee, MS, CGC is a certified genetic counselor (CGC) with over five years of practice in reproductive medicine. She worked for one of the most well-known IVF clinics in the US and for a genetic testing laboratory that offers fertility related genetic testing. Katie Lee currently works with one of the largest sperm banks in the county. She has two YouTube channels, one about miscarriage and fertility and another about the genetic counseling career. FAQs Answered:If you are coming back to school after working for a while, any tips for a smooth transition? And is there a way you would organize your notes/information from class to make it easily accessible for rotations?How can you avoid burnout as a genetic counseling student? How to take care of your mental health in a hectic environment?Which rotations will students experience in the first year of the program? Are these exclusively shadowing opportunities or do students engage in the session? How is the transition from telehealth to in person counseling? How many students attend NSGC? Has this changed with COVID-19 now that the conference is offered through virtual route as well? What are your recommendations for students during the conference? What is the timeline for the thesis project? Can students bring their own ideas to develop? Are thesis projects done in groups or individually? What's an example of an interesting thesis project? How often do students present their thesis poster at a conference?What classes are covered in the first year?Are there mentorship programs within grad school? Do these involve fellow students, faculty, supervisors, and/or patient advocates? Resources Mentioned:Dena DNA's book club list on Amazon. You can find many of the authors of these books as guests on DNA Today in these episodes. Rachel Mill's book recommendation of “Make It Stick: The Science of Successful Learning” By Peter C. BrownCheck out the “Genetic Counseling and the Future of Healthcare” on Clubhouse to participate in live genetic counseling conversations. Shoutout for The Genetic Counseling Virtual Career Fair on Sept 28th and Sept 29th. You will have the opportunity to find information about a career in genetic counseling from the National Society of Genetic Counselors and visit with over 50 masters level genetic counselor training programs in the United States and Canada. If you are a prospective student interested in genetic counseling and of minority background, we will also have a Minority Genetic Professionals Network room where you can talk to minority genetic counselors and students. Stay tuned for the next new episode of DNA Today on September 17th! New episodes are released on the first and third Friday of the month, with some bonus episodes here and there. In the meantime, you can binge over 150 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Episodes in 2021 are also recorded with video which you can watch on our YouTube channel. See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNApodcast.com. Questions/inquiries can be sent to info@DNApodcast.com.
Soo guys.. Kali ini SIBOI X HAMAS ABDULLAH bakal bahas mobil LCGC. Penasaran kan apa yang bakal kita bahas?, jangan lama-lama langsung dengarkan saja...
This week we speak with an anonymous listener who shares their journey of undergoing genetic testing for Frontotemporal Dementia (FTD). Tip: We recommend listening to Expert Chat: Genetics & FTD with Diane Lucente, MS, LCGC, Manager of Genetic Counseling at world renown Massachusetts General Hospital Frontotemporal Disorders Unit. Let us know what you think of the episode by commenting on the episode art on instagram. --- This Week's Sponsor: Click here to learn more about NeuroReserve and purchase their brain-health supplement RELEVATE and be sure to use code REMEMBERME for 15% off your order (including monthly subscriptions!) Get In Touch: Follow us on instagram @remembermepodcast, and visit our website www.remembermeftd.com for our blog, newsletter sign-up and more content! Support: You can support our podcast by buying us a coffee, shopping our merch store, leaving us an apple podcast review and spreading the word! --- Remember Me is a podcast created by two moms who became fast friends on Instagram while caregiving for their parents. It features stories of Frontotemporal Dementia (FTD) with a focus on remembering individuals for who they were before the disease. The stories shared are raw, real, and so full of love. We hope it inspires you to "accept the good." --- Support this podcast: https://anchor.fm/rememberme/support
Did you know that one of the biggest secret weapons in the war on #PancreaticCancer is our genetic code? The recent influx of people getting tested has led to this information becoming an integral part of pancreatic cancer treatment and prevention. It is no longer a one-size-fits-all approach. Genetic counselor, Dena Goldberg Linder, MS, LCGC, (Dena DNA) will provide you with the knowledge of how you and your relatives can use genetics as a tool in getting ahead of pancreatic and other cancers. With her visual approach to genetic education, she will make it easy to understand: -Basic cancer genetics -Hereditary pancreatic cancer syndromes -Why everyone with pancreatic cancer should be tested -Who needs to get testing, and how -Personalized treatments and family prevention For the full video episode and all previous episodes see our Wellness Wednesday playlist on YouTube HERE. For more resources visit: rolfefoundation.org Download/view worksheet here: https://rolfefoundation.sharepoint.co...
ASCO: You're listening to a podcast from Cancer.Net. This cancer information website is produced by the American Society of Clinical Oncology, known as ASCO, the world's leading professional organization for doctors who care for people with cancer. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Cancer research discussed in this podcast is ongoing, so the data described here may change as research progresses. Brielle Gregory Collins: Hi, everyone. I'm Brielle Gregory Collins, a member of the Cancer.Net Content Team, and I'll be your host for today's Cancer.Net podcast. Cancer.Net is the patient information website of ASCO, the American Society of Clinical Oncology. Today, we're going to be talking about genetic conditions linked to kidney cancer and what people with these conditions should know about genetic counseling. Our guests are Dr. Brian Shuch and Lauren Bear. Dr. Brian Shuch is the director of the Kidney Cancer Program at UCLA Health in Los Angeles, California. He is also 1 of the specialty editors for genitourinary cancers at Cancer.Net. Thanks for joining us today, Dr. Shuch. Dr. Brian Shuch: Great. Thanks for having me. Brielle Gregory Collins: Also joining us is Lauren Bear. Lauren Bear is the lead genetic counselor at the Familial Renal Cell Carcinoma and VHL Disease Clinic at Massachusetts General Hospital in Boston, Massachusetts. Thanks for joining us today, Ms. Bear. Lauren Bear: Thank you so much for having me. Brielle Gregory Collins: Before we begin, we should mention that Dr. Shuch and Ms. Bear do not have any relationships to disclose related to this podcast, but you can find their full disclosure statements on Cancer.Net. Now to start, Dr. Shuch, what is the definition of a genetic or inherited condition? Dr. Brian Shuch: Really, this is any condition that would develop that is really strongly influenced by somebody's genes that they would inherit from a family member. But there are lots of kind of complex definitions we can go into, but really anything that develops directly influenced or modulated by their genes that they inherit. Brielle Gregory Collins: Thank you for defining that. And how are genetic conditions diagnosed? Dr. Brian Shuch: So there are different ways, obviously, with the ability to have DNA sequencing done at a fraction of the cost from 10, 20 years ago, we can quickly and effectively sequence somebody's genes. But there are some times where we see patients that they have clinical features of a particular syndrome. And we have given patients a clinical diagnosis of that condition and follow them the same way if they meet some pre-specified criteria. But not every condition actually has a clinical diagnostic criteria. Brielle Gregory Collins: And getting into those specific conditions a little bit, briefly, what are some of the most common genetic conditions that are linked to kidney cancer? Dr. Brian Shuch: So there are about 18 different genes, which when inherited with a damaged copy, you potentially will have some increased risk. Some of them are the well characterized ones, which everyone is familiar with that have been around for decades. Most commonly, people are familiar with Von Hippel-Lindau, which has been described now about 100 years ago, but there are other conditions too. Birt-Hogg-Dubé, which is another common 1. The 1 that I study, hereditary leiomyomatosis and renal cell, we actually believe is the most common 1 based on newer data. But other ones, such as hereditary papillary renal cell, there's a bunch of ones linked to a hereditary paraganglioma syndrome called STH. But we have plenty of new and emerging conditions, and we're learning new things every year. Brielle Gregory Collins: Thank you for running through all of those. And if someone is diagnosed with kidney cancer, what are some of the signs that they might have 1 of these genetic conditions? Dr. Brian Shuch: So first and foremost, when you're with a patient, you look at their age and if someone has really early age of onset, it should be a red flag. Age alone is controversial whether you should do testing, but that should be a red flag. Whether someone has 1 tumor or more than 1 tumor obviously is important. Both kidneys or 1 kidney. But taking a family pedigree is very important. Most clinicians may just say any kidney cancer, but really understanding at least 2 or 3 generations can really help kind of outline somebody's inherited risk. Finally, the pathology. There are about 20 flavors of kidney cancer, not all of them have the same type of risk. But we actually can learn a lot from a very outstanding pathologist that looks with special immunostains or they look at particular features under the microscope. And a lot of times, a good pathologist can pick this up. And when they do, we have very high likelihood of diagnosing someone with a hereditary form of kidney cancer. Brielle Gregory Collins: Thank you. And as far as being diagnosed and how it affects the way someone is treated, can you describe how being diagnosed with a genetic condition may change the way kidney cancer is treated? Dr. Brian Shuch: So not all types of kidney cancer are the same. It is 1 of the most diverse forms of cancers that we have. Just because they arise from the kidney does not make them the same. There are some which are very indolent and other ones which are extremely aggressive. So if I found a patient with a 1-centimeter kidney tumor and I knew it was sporadic, I may consider watching that patient and doing what's called active surveillance. If it's a patient who actually is a family member of 1 of our patients just diagnosed with HLRCC, that patient was placed on active surveillance and there's no way we would watch that type of tumor because it has much more aggressive biological potential. We would definitely recommend intervention for someone with that type of disease. Biology of the tumor really predicts behavior. Brielle Gregory Collins: Thank you so much. And can you describe how common it is for someone to be diagnosed with inherited kidney cancer? Dr. Brian Shuch: So that's a great question. It's something which is not really perfectly understood at this time. There's been very wide estimates, anywhere from 1% to maybe 8% of kidney cancer might have a very strong inherited component, whether it's due to a single gene that also may be somewhat variable, but I would say it's probably less than 10% of patients actually have a strong inherited predisposition. So we don't refer all patients for testing. And everyone's threshold to send someone for testing varies. But I think obviously, talk to your clinician. I think in this era where testing is fairly cheap and the risks are very low, I think as a default, most clinicians should err on sending patients to a genetic counselor and the genetic counselor can walk things through. Often the history that a clinician takes is somewhat insufficient. And I think the genetic counselors are really great at going through a 3-generation pedigree and then deciding whether testing should be pursued. So not everyone should be referred and not everyone referred should actually undergo testing. But I think the first step usually comes with recognition by the clinician. I'm interested to hear what Lauren thinks about this as well. Lauren Bear: Yeah, I completely agree. It's a good point that we're more than happy to meet with any patient that a physician is concerned could have a hereditary kidney cancer condition. But exactly like Dr. Shuch described, not every family history is very high risk. And so, yeah, I completely agree. Brielle Gregory Collins: And Ms. Bear, I want to get into a little bit about genetic counseling. So if a person is referred to genetic counseling, how can they best prepare for their appointment? Lauren Bear: So during the visit, a genetic counselor will likely ask, as Dr. Shuch described, about their personal and family history to assess risk for 1 of these conditions. And there are some helpful things that people can prepare in advance for this appointment. First are factors related to their personal history. So like Dr. Shuch described, because some of these hereditary cancer syndromes are related to specific types of kidney cancer, it may be helpful to gather information about your own cancer diagnosis and your own personal medical history if it's not already included in the referral or the medical chart, and also gathering information about your family history. So asking some people to research with their family members to see who has had any cancer, what are the ages of diagnosis in their family members' medical history. And that often, again, like Dr. Shuch described, will be to ask about children, siblings, parents, and grandparents to create that 3-generation pedigree or family tree. I think sometimes patients like to discuss the appointment in general with their family member before it happens, because the process of genetic counseling can often involve this option of genetic testing, which could have impact on family members. So beginning that conversation early with relatives can be helpful sometimes. And lastly, some patients like to talk to their insurance carrier about coverage of the appointment itself or even about the genetic testing, although very often talking about the actual genetic testing coverage will be discussed at the appointment with the genetic counselor. So working in advance to get some of these things together can be really helpful to prepare. Brielle Gregory Collins: Got it. And as far as the meeting itself, what happens during and after the initial meeting with the genetic counselor? Lauren Bear: Yeah, so overall, the genetic counseling appointment will involve a genetic evaluation during the initial session and then afterwards, a discussion about any test results and/or follow-up recommendations for the patient and their family members. So during the session, as I stated before, the genetic counselor will ask about this personal and family history and ask about other features that may be suggestive of a known hereditary kidney cancer syndrome. Sometimes that might involve a physical exam with a physician, depending on the indication or the clinic set-up. The genetic counselor will provide basic understanding of genetics and the basis of hereditary kidney cancer to make sure the information that is shared and the recommendations are all put into context for the patient and their family. And then, based on the factors seen in the personal and family history, the genetic counselor will provide a risk assessment, which is a discussion of the possible genetic risk factors that could be explaining the kidney cancer or other cancers in the family. And as, again, Dr. Shuch described, to evaluate very often, this can include a discussion about genetic testing, which can be done on blood or saliva. Both are equally accurate, and it often can be performed via a multigene panel where we look at more than 1 of these conditions at once. But it's also important to realize that this testing is optional. So it is up to the patient if they would like to proceed with any of this testing. And an informed consent is a really important part of this discussion as well, to make sure the patient understands the benefits and limitations of this testing and to confirm if they do or do not want to move forward with the testing. So that's overall what happens during the session and afterwards, if testing is performed, then genetic testing results are communicated to the patient. Depends on the clinic set-up how that's done, if it's through a telephone call, virtual visit, in-person visit. This may be together with the physician, again, depending on the set-up. But in this results disclosure, the genetic counselors and the medical team, they're equipped to convey these results with their patients. So they keep it in context with their own personal and family history and to help the patient adjust to the results, whatever the results are, because learning about genetic test results can sometimes be challenging. So a genetic counselor's role is to provide support and help the patient adjust however they can. Brielle Gregory Collins: So it sounds like it's really a discussion between the patient, their genetic counselor, and the rest of their health care team to see if genetic testing is something that's right for them. Lauren Bear: That's exactly right. That's exactly right. Brielle Gregory Collins: Got it. And how does meeting with the genetic counselor help a person with kidney cancer and their family? Lauren Bear: So when someone first learns there's a possibility of a hereditary reason behind their kidney cancer, many questions or feelings may arise from how this could impact their own health and how it could also impact the health of their family members. And this is all very natural. So the goal, as I stated before, is for the genetic counselor to help guide the patient and their family members to learn more about their risk and figure out who else might be at risk in their family. So, for example, if a positive test result is found or a diagnosis of a hereditary kidney cancer syndrome is made, the genetic counselor's skills are to identify the appropriate follow-up for that patient. So whether it's follow up with a physician to monitor for potentially another kidney cancer, or some other type of cancer, or some other symptom related to these conditions that Dr. Shuch described. And so that's part of when we're thinking about the genetic counselor's role with the patient and their own medical care, it's for that follow-up and helping them adjust. When we think about for their family, a genetic counselor's role would be to help identify who might be at risk. So discussing cancer risk in families is not always the top of conversation. And so the role of the genetic counselor is to help work through ways to facilitate these conversations with family members. Not everybody in the family may be interested at that moment to do genetic testing. So working with a genetic counselor can be helpful in brainstorming ways to share this information with family. Other times, family members are very eager to pursue genetic testing at that moment, so genetic counselors can help set up those consultations or find local resources. So often, long-term relationships can be established with a genetic counselor and the family and the patient. And then also, if a negative result is obtained, there's no gene mutation detected and the patient's not diagnosed with a known hereditary kidney cancer syndrome, the medical team and genetic counselor may also still be able to provide recommendations as far as screening for the family. So it's not to say only if a positive result is found are recommendations made. So those are kind of how I think about how a genetic counselor can impact the patient and their families in a situation like this. Brielle Gregory Collins: Thank you so much for walking through that. So for someone who is diagnosed with 1 of these genetic conditions, what are some tips that you'd share about how they can discuss the genetic condition related to their kidney cancer with their family? Lauren Bear: Every family is very different and the genetic counselors and the physicians, their specialty is to help walk a patient through how family members might react to this kind of information and what kind of materials may be helpful to have on hand when someone wants to share this information with their family members. Many genetic counselors supply family letters detailing the results that the patient is welcome to share with their relatives, certain handouts. We've had family meetings and conference calls, which can be helpful tools. And so really the genetic counselor is really trying to help the patients have the language to facilitate these conversations or to have their own understanding. So if they can absorb this information themselves, they may be more comfortable sharing it with their relatives. And that process might take a little while to adjust to this information, to give yourself some time to ask questions of your own medical team so you can educate yourself and then feel comfortable to share it. Sometimes these discussions happen with children who may be at risk for hereditary cancer, kidney cancer syndrome. So making sure to use age-appropriate language and also having more of like an ongoing conversation rather than a one-time conversation with children can be helpful. But as with anything, as questions come up, I always say, "Don't hesitate to reach out to the genetic counselors or your medical team. We're here to help." Brielle Gregory Collins: That's all really helpful. Thank you so much for your time and for sharing your expertise today, Dr. Shuch and Ms. Bear. It was great having you. Lauren Bear: Thank you for having me. Dr. Brian Shuch: Thank you. ASCO: If this podcast was useful, please take a minute to subscribe, rate, and review the show on Apple Podcasts or Google Play. This Cancer.Net podcast is part of the ASCO Podcast Network. This collection of 9 programs offers insight into the world of cancer care, covering a range of educational, inspirational, and scientific content. You can find all 9 shows, including this one, at podcast.asco.org. Cancer.Net is supported by Conquer Cancer, the ASCO Foundation, which funds breakthrough research for every type of cancer, helping patients everywhere. To help fund Cancer.Net and programs like it, donate at conquer.org/donate.
#SientaFiesta kali ini ngobrol tentang mobilnya Mas Adhil --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/whatsyourride/message Support this podcast: https://anchor.fm/whatsyourride/support
While diet and lifestyle play a large role in developing heart disease, research has found that as much as 30 percent of heart disease cases are influenced by genetic factors. Anjan Tibrewala, MD, heart failure specialist at Northwestern Medicine Central DuPage Hospital and Delnor Hospital, and Rebecca VanDyke, MS, LCGC, licensed genetic counselor at Northwestern Medicine Central DuPage Hospital, discuss how genetic testing can provide patients with a sophisticated and personalized cardiovascular evaluation that has implications on the diagnosis, prognosis and management of heart conditions.
On the next episode of Rosé and DNA, we share some wine (and cranberry juice!) with Dr. Altovise Ewing! Dr. Ewing received her PhD in genetics/genetic counseling from Howard University, previously worked at 23andMe, and now works as a Global Health Equity Strategist for Genentech. Dr. Ewing has a clear vision for how the field of genetics and medical research can engage thoughtfully and responsibly with underserved communities, with the goal of improving outcomes for communities of color. Dr. Ewing's favorite causes: Painted Pink for Breast Cancer (PaintedPink.org) - #Blackowned non-profit empowering millennials to take charge of their breast health Satcher Health Leadership Institute (satcherinstitute.org) - aims to be the leading transformational force for health equity in policy, leadership development, and research Equal Justice Initiative (eji.org) - works to end mass incarceration, excessive punishment, and racial inequality Wines tasted: Riesling from Alice Hartmann, a vineyard in the Mosel region of Europe - light, crisp, and fruity! Rosé from Gérard Bertrand - not too sweet, pale pink, and packaged in a pretty bottle!
With Pastor Tony Rapu
Christine Hake, MS, LCGC explains what a genetic counselor is, what to expect at a genetic counseling visit, the different genetic tests available, why you might be referred to a genetic counselor, and if genetic testing is covered by insurance.