Podcast appearances and mentions of brain organoids

How do you recreate a brain circuit in a dish, and what can it unlock about our minds? Neil deGrasse Tyson, Chuck Nice, and Gary O'Reilly explore the frontier of neuroscience with Stanford neuroscientist Sergiu Pașca, to break down stem cells, how the brain forms itself, and assembloids: self-organizing brain circuits.NOTE: StarTalk+ Patrons can listen to this entire episode commercial-freehttps://startalkmedia.com/show/assembloids-recreating-the-brain-with-sergiu-pasca/Thanks to our Patrons Andy Fleishman, Khal Khumalo, Mauritz Cronje, Kyle Stone, Kathleen Fitzpatrick, Ridge Glenn, Josh Gumina, Mike Evans, Eddie Trapp, Aaron Turetsky, Kenneth TRan, Deeks, Patrick Weglinski, João Bruno Agria Russo, Lester Fernandez, Shani, Jorge Zok Yepiz, Devin Waldron, Eric D, Luke Landry, Chase Snow, Micheal Wall (Bean), Stefan, Tori Kishman, James Sellers, Alex Hayman, Kyle Gosser, Maria Balog, Vytautas Jasas, Cainã Kubiaki, Ryan Berube, James Randall, QuirkyCollisions, Bryan Staley, Jake, James Fuller, Will Behave, Gordon Pluemer, Bob Dietrich, Pizza Pockets, Nip34, Sh40l1nmunk Munken, Nick Hanna, Lyman Jordan, Robert Brashear, Lemon Life, Azeem Ahmed, John Barry, Tomas Gomez, and Joss in Cambodia for supporting us this week. Subscribe to SiriusXM Podcasts+ to listen to new episodes of StarTalk Radio ad-free and a whole week early.Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

Are we on the brink of merging with machines? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O'Reilly dive into the mysteries of consciousness versus intelligence, panpsychism, and AI with neuroscientist and author Anil Seth.NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here:https://startalkmedia.com/show/is-consciousness-everywhere-with-anil-seth/Thanks to our Patrons James Boothe, Vicken Serpakian, John Webb, Doctor Pants, Greg Gralenski, Lost_AI, Bob Lester, kim christensen, Micheal Gannon, Aaron Rosenberg, Shai Kr, Kyle Bullock, JyinxTV, James Myers, victor recabarren, David Pederson, Ted McSheehy, Terena, Tracy Sheckells, Groovemaster24, Sheedrealmusic, David Amicucci, Brian Ridge, M Ranger, Peter Ackerman, Mars Colony AI, DonAlan, Harry Sørensen, G Anthony, Muhammad Umer, and Joshua MacDonald for supporting us this week. Subscribe to SiriusXM Podcasts+ on Apple Podcasts to listen to new episodes ad-free and a whole week early.

*00:00 – 00:00* Intro *00:06 – 00:09*  *CES & AI Everywhere*  Discussion of new tech at CES (Consumer Electronics Show).  Joking about AI ovens, AI guitars, and the feeling that everything is suddenly “smart.”*00:09 – 00:12*  *NVIDIA Supercomputers & Exaflops*  Awe at how new hardware can process “the entire internet.”  Talk of energy consumption, fossil fuels vs. nuclear, and whether AI will force an energy revolution.*00:12 – 00:15*  *Industrial Revolution Parallel*  Comparing AI's potential impact to the Industrial Revolution.  Concern about environmental strain, greed, and unstoppable progress.*00:15 – 00:18*  *Vonnegut's *Player Piano & Self-Driving Cars**  Reading a Kurt Vonnegut quote on technology replacing humans.  Rant about driverless cars, personal autonomy, and why society resists better public infrastructure.*00:24 – 00:27*  *Roman Empire & Modern Parallels*  Drawing lines from Ancient Rome's “bread and circuses” to today's consumer culture.  Government structures modeled on Greek/Roman systems.*00:33 – 00:36*  *New “Religion” Idea: PFG*  “Powerful People for Good”—recognizing your decisions have a ripple effect.  A playful framework for making better choices that benefit yourself and others.*00:36 – 00:39*  *Council of Nicaea & Jesus' Divinity*  A quick historical aside about the year 325 CE, Arianism, and the “election” of Christ's divine status.  Santa Claus (St. Nicholas) allegedly slapping Arius—fun historical tidbit.*00:39 – 00:42*  *Cheese Heist at Neal's Yard Dairy*  News of a massive cheddar cheese theft.  Speculation on how thieves offload that much specialty cheese.

In this episode, we go through the process of examining the many extant and potential benefits, pitfalls, and psychological as well as ethical conundrums concerning Brain Organoids.

THIS WEEK!!!!  First and foremost, we are now streaming [some, maybe all?] episodes with visuals of us making the sausage in The Infamous Studio B, and that includes THIS EPISODE! For followers on our Podcasting streams, we still love you, and will also release every episode PLUS some bonus content to your Podcast feed.  Anyhow, we're doing tunes about Thousandaires, farts, Cape fear, Brain Organoids (which is a companion song to a BONUS episode also released with this one!), and also Clown College. Yeah. Which is where we obviously went. OBVIOUSLY. But for real, go check out Graham's newly yoked and cut-ass bod on YouTube. GET IT!   

Giorgia Quadrato, Ph.D., explores cerebral organoids as models for neural development and disease research. Using live calcium imaging, Quadrato observes increased neuronal coordination attributed to inhibitory neurons, validated through pharmacological and genetic methods. Quadrato contrasts their organoid generation protocol with previous methods, emphasizing complex patterning, long-term cultures, and co-culture with mouse brain cells for improved physiological relevance. Microfluidics are utilized for enhanced oxygenation and physiological conditions. Future efforts focus on incorporating microglial cells for synaptic pruning studies and overcoming challenges in cryopreservation. Overall, the research aims to advance understanding of neural mechanisms and diseases, enhancing organoid fidelity for biomedical applications. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39456]

Giorgia Quadrato, Ph.D., explores cerebral organoids as models for neural development and disease research. Using live calcium imaging, Quadrato observes increased neuronal coordination attributed to inhibitory neurons, validated through pharmacological and genetic methods. Quadrato contrasts their organoid generation protocol with previous methods, emphasizing complex patterning, long-term cultures, and co-culture with mouse brain cells for improved physiological relevance. Microfluidics are utilized for enhanced oxygenation and physiological conditions. Future efforts focus on incorporating microglial cells for synaptic pruning studies and overcoming challenges in cryopreservation. Overall, the research aims to advance understanding of neural mechanisms and diseases, enhancing organoid fidelity for biomedical applications. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39456]

Giorgia Quadrato, Ph.D., explores cerebral organoids as models for neural development and disease research. Using live calcium imaging, Quadrato observes increased neuronal coordination attributed to inhibitory neurons, validated through pharmacological and genetic methods. Quadrato contrasts their organoid generation protocol with previous methods, emphasizing complex patterning, long-term cultures, and co-culture with mouse brain cells for improved physiological relevance. Microfluidics are utilized for enhanced oxygenation and physiological conditions. Future efforts focus on incorporating microglial cells for synaptic pruning studies and overcoming challenges in cryopreservation. Overall, the research aims to advance understanding of neural mechanisms and diseases, enhancing organoid fidelity for biomedical applications. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39456]

Giorgia Quadrato, Ph.D., explores cerebral organoids as models for neural development and disease research. Using live calcium imaging, Quadrato observes increased neuronal coordination attributed to inhibitory neurons, validated through pharmacological and genetic methods. Quadrato contrasts their organoid generation protocol with previous methods, emphasizing complex patterning, long-term cultures, and co-culture with mouse brain cells for improved physiological relevance. Microfluidics are utilized for enhanced oxygenation and physiological conditions. Future efforts focus on incorporating microglial cells for synaptic pruning studies and overcoming challenges in cryopreservation. Overall, the research aims to advance understanding of neural mechanisms and diseases, enhancing organoid fidelity for biomedical applications. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39456]

Giorgia Quadrato, Ph.D., explores cerebral organoids as models for neural development and disease research. Using live calcium imaging, Quadrato observes increased neuronal coordination attributed to inhibitory neurons, validated through pharmacological and genetic methods. Quadrato contrasts their organoid generation protocol with previous methods, emphasizing complex patterning, long-term cultures, and co-culture with mouse brain cells for improved physiological relevance. Microfluidics are utilized for enhanced oxygenation and physiological conditions. Future efforts focus on incorporating microglial cells for synaptic pruning studies and overcoming challenges in cryopreservation. Overall, the research aims to advance understanding of neural mechanisms and diseases, enhancing organoid fidelity for biomedical applications. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39456]

Giorgia Quadrato, Ph.D., explores cerebral organoids as models for neural development and disease research. Using live calcium imaging, Quadrato observes increased neuronal coordination attributed to inhibitory neurons, validated through pharmacological and genetic methods. Quadrato contrasts their organoid generation protocol with previous methods, emphasizing complex patterning, long-term cultures, and co-culture with mouse brain cells for improved physiological relevance. Microfluidics are utilized for enhanced oxygenation and physiological conditions. Future efforts focus on incorporating microglial cells for synaptic pruning studies and overcoming challenges in cryopreservation. Overall, the research aims to advance understanding of neural mechanisms and diseases, enhancing organoid fidelity for biomedical applications. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39456]

Dr. Ziyuan Guo is an Assistant Professor of Pediatrics at the Center for Stem Cell & Organoid Medicine at Cincinnati Children's Hospital. He talks about in vivo reprogramming and cell and gene therapy in neurodevelopmental and neurodegenerative disorders. He also discusses assembloids to model the blood-brain barrier and strategies for organoid vascularization.

NNN Website https://sites.google.com/view/alientom/home Bird Flu, Hunter Biden, WW3, Alex Jones, X, Digital ID, Israeli Intelligence, Brain Organoids, Algorithms, Free speech, Hunter Biden, Putin, Justin Trudeau, heart attack and stroke, cancer, Tucker Carlson, Elon Musk, Trump, censorship, Dr. Fauci, NIH, NATO, Russia, October 7th, oct 7, Netanyahu, Hamas

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Hugging Face targeted by hackers, comprising several of their user’s sensitive and private information. Artie Intel and Micheline Learning report on Artificial Intelligence for the AI Report. Nvidia unveils next-gen AI chips. Swiss startup trains ‘living’ computers. AI is about to seriously disrupt the hospitality industry. Researchers use an AI brain map to decode Alzheimer’s and autism.

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Women across industries need more female mentors and role models and nowhere is that more imperative than in the field of STEM (science, technology, engineering, and mathematics). When we have more women in STEM, there's a ripple effect — scientific and financial outcomes for women are improved across the board.  The good news is that more women than ever are choosing career paths in the field. Paola Arlotta, a neurobiologist and stem cell scientist at Harvard University is one of those women. She's paving the way for other female scientists and showing that it's possible to run a lab and raise a family at the same time.  Takeaways: Brain organoids are tiny pieces of brain tissue that are made in a lab from stem cells. They can be used to study the development of the human brain and understand neurological diseases. Brain organoids have the potential to revolutionize drug development and personalized medicine.  There are many different ways to be successful in science, and it's important to find your own path. Having diverse role models is crucial for inspiring and empowering women in science. Balancing a career in science with family life requires support and collaboration. Advancements in technology and data analysis will lead to a leap forward in drug development and disease understanding. Chapters: 00:00:00 - Introduction 00:01:33 - Paolo Arlotta's Background and Decision to Pursue Science 00:06:24 - The Process and Significance of Creating Brain Organoids 00:10:25 - The Potential of Brain Organoids in Understanding and Treating Diseases 00:22:01 - Women in Science 00:28:12 - Challenges of Balancing Career and Family 00:31:01 - Role Models and Mentorship 00:34:52 - Lightning Round Questions Join us! Snag all the latest episodes, savvy budgeting tips, investing advice, and even giveaways via the HerMoney Newsletter at Hermoney.com/subscribe! Learn more about your ad choices. Visit megaphone.fm/adchoices

Guest Sergiu Pasca is a physician-scientist who turns skin cells into stem cells and then into brain tissues he calls “organoids” and “assembloids” in order to study psychiatric and neurological illness in a dish instead of in living human beings. With this knowledge, Pasca hopes to develop new treatments for conditions ranging from schizophrenia and autism spectrum disorders to chronic pain, he tells host Russ Altman in this episode of Stanford Engineering's The Future of Everything podcast.Episode Reference Links:Sergiu's Lab: Pasca LabSergiu's Stanford Profile: WebsiteCenter at Stanford Sergiu Leads: Stanford Brain OrganogenesisSergiu's recently published paper: Antisense Oligonucleotide Therapeutic Approach for Timothy SyndromePaper by Shinya Yamanaka Sergiu discusses: Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast CulturesConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/XChapters:(00:00:00) IntroductionRuss introduces guest, Sergiu Pasca, professor of Psychiatry and Behavioral Sciences at Stanford University.(00:02:43) The Science of Growing Brain Tissue from Skin CellsThe process of developing brain organoids from skin cells and the potential medical applications of these models.(00:03:59) Enhancing Neurological Research ToolsAdvancing the complexity of brain models to include various brain structures and their applications in modeling diseases.(00:07:20) Introduction of AssembloidsIntroduction to assembloids, detailing how combining different organoids can mimic complex brain structures(0015:58) Testing Therapeutics Using Humanized ModelsThe innovative approach of using humanized rat models to test neurological therapies and drugs.(00:21:03) Complex Circuit Modelling for Disease UnderstandingThe current capabilities of modeling complex brain circuits and their relevance in  understanding the neural pathways involved in diseases.(00:23:36) The Future of Pain Modelling and Drug TestingHow assembled brain cells can model pain perception and response, leading to potential new treatments for chronic pain and psychiatric disorders(00:27:46) Ethical Considerations and Public EngagementEthical concerns related to creating brain-like tissues and the importance of public engagement in scientific research.(00:32:01) Future Directions and Global CollaborationThe future of brain organogenesis research and the potential impacts on treating neurological and psychiatric conditions.(00:34:05) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads or Twitter/XConnect with School of Engineering >>> Twitter/X

Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]

Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]

Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]

Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]

Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]

Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]

Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]

Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]

Summary In this episode of BioTalk Unzipped, the hosts discuss the applications and ethical concerns surrounding organoids, which are 3D cell clusters that mimic the features of full-sized organs. They explore the potential of brain organoids in brain-computer interfaces and neuroplasticity. The conversation then shifts to the impact of AI and data sciences in healthcare, with a focus on the challenges and opportunities in implementing AI strategies. The hosts also discuss the future of quantum computing in healthcare and the FDA's IT strategy with 21 CFR Part 11.  Chapters 01:14 - Introduction to BioTalk Unzipped 03:30 - NEW NEWS: Discussion on Organoids and Their Applications  04:45 - Ethical Concerns with Brain Organoids as mini bio-computers 06:31 - Organoid Possibilities in Drug Discovery Research and Brain Interfaces 08:59 - The Potential of Brain Training and Neuroplasticity 10:51 - The Impact of AI and Data Sciences in Healthcare 11:18 - Jason's Background and Emerging Technologies Transforming Clinical Research 13:43 - The Role of AI in Precision Medicine, Quantum Computing and Business Growth 24:15 - FDA's IT Strategy and the Challenges of Implementing AI 26:32 - The Importance of Strategy and Prioritization in IT, Data Integrity, and 21 CFR Part 11 How to reach us: Jason Burke https://www.linkedin.com/in/jasonburke/ Creo Inc. -  https://www.creoinc.net/  Dr. Chad Briscoe https://www.linkedin.com/in/chadbriscoe/ Celerion - https://www.celerion.com/  Gregory Austin https://www.linkedin.com/in/gregoryaustin1/ ECI - https://eci-rx.com/  New News Link: The many uses of mini-organs https://www.technologyreview.com/2024/03/08/1089612/the-many-uses-of-mini-organs/  Image Credits Brain - https://www.vecteezy.com/vector-art/658977-kawaii-cute-happy-brain-with-arms-and-legs UFO - https://www.pinterest.com/pin/swampthingy--675891856570360044/ #HealthcareInnovation #Organoids #AI #QuantumComputing #Podcast #BioTalkUnzipped #drugdiscovery

SummaryBrain Organelles, A.I. and Defining Intelligence in Nature- In this episode, we continue our fascinating interview with GT, a science content creator on TikTok and YouTube known for their captivating - and sometimes disturbing science content. GT can be found on the handle ‘@bearBaitOfficial' on most social media channels. In this episode, we resume our discussion on Brain Organelles - which are grown from human stem cells - how they are being used to learn about disease, how they may be integrated in A.I. as well as eithical concerns with them. We also ponder what constitutes intelligence in nature, and even touch on the potential risks of AI behaving nefariously. You won't want to miss this thought-provoking and engaging discussion.30% Off ZenCastr DiscountUse My Special Link to save e 30% Off Your First Month of Any ZenCastr Paid Plan

SummaryThis conversation explores the topic of brain organoids and their integration with robots. The discussion covers the development and capabilities of brain organoids, the ethical implications of their use, and the differences between sentience and consciousness. The conversation also delves into the efficiency of human neural networks compared to artificial neural networks, the presence of sleep in brain organoids, and the potential for genetic memories in these structures. The episode concludes with an invitation to part two of the interview and a mention of the podcast's Patreon offering a commercial-free version of the episode.TakeawaysBrain organoids are capable of firing neural signals and forming structures similar to those in the human brain during development.The ethical implications of using brain organoids in research and integrating them with robots raise important questions about sentience and consciousness.Human neural networks are more efficient than artificial neural networks, but the reasons for this efficiency are still unknown.Brain organoids exhibit sleep-like patterns and can undergo dendrite growth, potentially indicating learning capabilities.Collaboration between scientists with different thinking skill sets is crucial for advancing research in brain organoids and related fields.Chapters00:00 Introduction: Brain Organoids and Robots00:39 Brain Organoids and Development01:21 Ethical Implications of Brain Organoids03:14 Summary and Introduction to Guest03:41 Sentience and Consciousness in Brain Organoids04:10 Neuron Count and Pain Receptors in Brain Organoids05:00 Unanswered Questions and Discomfort05:25 Psychological Discomfort in Brain Organoids06:21 Early Videos and Brain Organoid Learning07:20 Efficiency of Human Neural Networks08:12 Sleep in Brain Organoids09:13 Delta Brainwaves and Brain Organoids10:11 Creating Brain Organoids with Specific Components11:10 Genetic Memories in Brain Organoids12:07 Efficiency and Learning in Human Brains13:00 Sequential Memory and Chimpanzees14:18 Different Thinking Skill Sets and Collaboration16:13 ADHD and Hyperfocusing18:01 Ethical Considerations in Brain Research19:23 Understanding Genetic Mutations20:51 Brain Organoids in Rat Bodies22:14 Dendrite Growth in Brain Organoids23:11 Duration of Dendrite Growth24:26 Genetic Memory Transfer in Brain Organoids25:19 Social Media Presence of Brain Organoid Companies26:15 Brain Organoids Controlling Robot Spiders27:14 Conclusion and Invitation to Part 2References:Muotri Labs (Brain Organelle piloting Spider Robot)Cortical Labs (Brain Organelle's trained to play Pong)*For a copy of the episode transcript, email us at breakingmathpodcast@gmail.com Become a supporter of this podcast: https://www.spreaker.com/podcast/breaking-math-podcast--5545277/support.

Fusebox 239: “Seasons Pleadings”” 28:30 – Show Intro, Season's Sneezings, Timo's Holiday Awful-ring, A Pause In The Disaster, Clip From Fusebox 219: “The Frankenstein Martini”, Clip From Fusebox 214: “Brain Organoids”, Clip From Fusebox 229: “Meet Kyle The Kinkajou”, Clip From Fusebox 217: “Color Bars”, Fusebox ID, Grindhouse Resurrection Spot 3, Fusebox Liner ID, Clip […]

Robert T. Fremeau, Jr., Ph.D., delves into Rett syndrome, a complex neurological condition. His research with brain organoids unveils its origins and progression. Fremeau uncovers disease markers and innovative treatments, offering insight into the pursuit of breakthrough therapies. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39167]

Robert T. Fremeau, Jr., Ph.D., delves into Rett syndrome, a complex neurological condition. His research with brain organoids unveils its origins and progression. Fremeau uncovers disease markers and innovative treatments, offering insight into the pursuit of breakthrough therapies. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39167]

Robert T. Fremeau, Jr., Ph.D., delves into Rett syndrome, a complex neurological condition. His research with brain organoids unveils its origins and progression. Fremeau uncovers disease markers and innovative treatments, offering insight into the pursuit of breakthrough therapies. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39167]

Robert T. Fremeau, Jr., Ph.D., delves into Rett syndrome, a complex neurological condition. His research with brain organoids unveils its origins and progression. Fremeau uncovers disease markers and innovative treatments, offering insight into the pursuit of breakthrough therapies. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39167]

Robert T. Fremeau, Jr., Ph.D., delves into Rett syndrome, a complex neurological condition. His research with brain organoids unveils its origins and progression. Fremeau uncovers disease markers and innovative treatments, offering insight into the pursuit of breakthrough therapies. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39167]

Robert T. Fremeau, Jr., Ph.D., delves into Rett syndrome, a complex neurological condition. His research with brain organoids unveils its origins and progression. Fremeau uncovers disease markers and innovative treatments, offering insight into the pursuit of breakthrough therapies. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39167]

Eric Courchesne, Ph.D., explores autism, highlighting its complexity beyond the brain and its connection to genetics and brain development. He focuses on the "temporal cortex," a crucial area in autism research associated with gene regulation and social processing. Courchesne also shares how his personal journey with polio has informed his thinking on neurodiversity, research, and beating the odds. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39171]

Eric Courchesne, Ph.D., explores autism, highlighting its complexity beyond the brain and its connection to genetics and brain development. He focuses on the "temporal cortex," a crucial area in autism research associated with gene regulation and social processing. Courchesne also shares how his personal journey with polio has informed his thinking on neurodiversity, research, and beating the odds. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39171]

Eric Courchesne, Ph.D., explores autism, highlighting its complexity beyond the brain and its connection to genetics and brain development. He focuses on the "temporal cortex," a crucial area in autism research associated with gene regulation and social processing. Courchesne also shares how his personal journey with polio has informed his thinking on neurodiversity, research, and beating the odds. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39171]

Eric Courchesne, Ph.D., explores autism, highlighting its complexity beyond the brain and its connection to genetics and brain development. He focuses on the "temporal cortex," a crucial area in autism research associated with gene regulation and social processing. Courchesne also shares how his personal journey with polio has informed his thinking on neurodiversity, research, and beating the odds. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39171]

Eric Courchesne, Ph.D., explores autism, highlighting its complexity beyond the brain and its connection to genetics and brain development. He focuses on the "temporal cortex," a crucial area in autism research associated with gene regulation and social processing. Courchesne also shares how his personal journey with polio has informed his thinking on neurodiversity, research, and beating the odds. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39171]

Eric Courchesne, Ph.D., explores autism, highlighting its complexity beyond the brain and its connection to genetics and brain development. He focuses on the "temporal cortex," a crucial area in autism research associated with gene regulation and social processing. Courchesne also shares how his personal journey with polio has informed his thinking on neurodiversity, research, and beating the odds. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39171]

In the first episode of our 3-part Halloween series, Dave Egts, Mulesoft Public Sector Field CTO at Salesforce, details what's scaring the public sector most and how Salesforce is utilizing - and securing - AI to improve customer experience with their Einstein Trust Layer. Additionally, Carolyn and Dave dive into the spooky worlds of brain cell chips, mind-reading AI and more.Key Topics[02:17] Starting the Dave & Gunnar Show[04:14] Dave's Role At Salesforce[05:18] What's Scaring the Public Sector Most?[10:22] Ways Agencies are Attracting Talent[13:56] How Agencies Are Handling Legacy Systems[15:45] What MuleSoft Does & Generative AI's Role[22:44] Salesforce's Einstein Trust Layer[29:21] PoisonGPT[36:07] Brain Organoids & Other Spooky, Ethically Questionable Experiments[42:15] Tech Talk Questions: Halloween Edition Quotable QuotesConsiderations for the Public Sector While Using AI: "As you're going on your AI journey, you've got to be looking at the EULA [End User License Agreement] and making sure that, okay, if I give you data, what are you going to do with it?"On Bias & Disinformation in Generative AI: "There were some previous studies that show that people are more likely to go with the generative AI results if they trust the company and they trust the model. So it's like, 'Oh, it came from Google, so how can that be wrong?' Or 'I'm trusting the brand,' or 'I'm trusting the model.'"About Our GuestDavid Egts is MuleSoft's first-ever Public Sector field CTO. Outside of MuleSoft, David is the founding co-chair of the WashingtonExec CTO Council, where he advises numerous companies on working with the public sector. David has received numerous industry-wide recognitions, including as an FCW Federal 100 winner, a FedScoop 50 Industry Leadership awardee and one of WashingtonExec's Top Cloud Executives to Watch. He has won multiple employee honors from Red Hat, Silicon Graphics and Concurrent Technologies Corporation.Episode LinksDave & Gunnar Show EpisodesEpisode 165- If you can't measure it, you can't manage itEpisode 185- In Your Brain, Nobody Can Hear You ScreamEpisode 227- Meetings and PunishmentEpisodes 248 & 249- Stay tuned to the Dave & Gunnar Show for these episodes to go liveAdditional LinksMinority Report Cuyahoga Valley National ParkFlowers For Algernon

In this episode:00:45 Implanted brain organoids could offer new insights into diseaseBrain organoids — lab-grown, self-organizing structures made of stem cells — are used in research to better understand brain development and disease progression. However, these structures lack connections seen in real brains, limiting their usefulness. To overcome this, a team has now transplanted human organoids into the brains of newborn rats, showing that these implanted organoids respond to stimuli and could influence the animals' behaviour.Research article: Revah et al.News and Views: Human brain organoids influence rat behaviour09:20 Research HighlightsThe subtle timing shift that gives jazz music its ‘swing', and why hydrogen power could be a cost-effective way to reduce heavy industry emissions in China. Research Highlight: What gives jazz its swing? A delay makes the differenceResearch Highlight: Hydrogen could help China's heavy industry to get greener11:46 The exoskeleton boot that makes walking more efficientWearable robotic exoskeletons that aid or enhance movement are fast becoming a reality, but there are challenges to overcome — to work best these devices frequently require careful calibration for their user using specialist equipment and time in a lab. Now, a team have created exoskeleton boots that can help people walk faster and more efficiently by learning and adapting to the wearer's gait as they walk. They hope that this approach could be used to develop personalised assistive devices in the future.Research article: Slade et al.Nature Video: The robot boot that learns as you walkSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.