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We were joined by Tim Staudt from Staudt on Sports in Lansing. He updated us on what he's heard in regards to Jonathan Smith keeping his job at MSU, they talked about that loss to Penn State on Saturday, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
In our second hour, Clayton Sayfie from theWolverine.com joined us to talk about Michigan's win over Northwestern. He and Huge talked about the positives and negatives they took from that game, gave their thought's on what improvements need to be made, looked ahead on the schedule, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He updated us on what he's heard in regards to Jonathan Smith keeping his job at MSU, they talked about that loss to Penn State on Saturday, and more. Anthony Broome from theWolverine.com then joined us to give his thought's on how Michigan Hoops have looked this season. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today on the show, we're talking about the Detroit Lions, Michigan and Michigan State Athletics, and more as we were joined by some of our great guests. We kicked off the show talking about the Lions as we were joined by Jeff Risdon from Lions Wire. He and Huge talked about all the things that went wrong for the Lions in that loss to the Eagles, talked about adjustments the team needs to move moving forward, talked about expectations for the rest of the season, and much more. We were then joined by Greg Heeres who is another one of our Lions insiders. He and Huge talked about how Goff played in that game, went through some of the numbers from last night, and Greg also told us how he can help you with Succession planning. In our second hour, Clayton Sayfie from theWolverine.com joined us to talk about Michigan's win over Northwestern. He and Huge talked about the positives and negatives they took from that game, gave their thought's on what improvements need to be made, looked ahead on the schedule, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He updated us on what he's heard in regards to Jonathan Smith keeping his job at MSU, they talked about that loss to Penn State on Saturday, and more. Anthony Broome from theWolverine.com then joined us to give his thought's on how Michigan Hoops have looked this season. In our final hour, we were joined by Scott Bischoff from the Detroit Lions Podcast. He and Huge gave their thought's on the poor performance the Lions had against the Eagles, talked about how great the Defense played last night, gave their thought's on what the Lions could've done differently, and much more. Chris Balas from theWolverine.com then joined us to talk about Michigan's win over Northwestern. He and Huge talked about how the Wolverines looked in that game as a whole, gave their thought's what improvement's they'd like to see from Michigan moving forward, and more. We wrapped up the show talking about the Lions as we were joined by John Maakaron from Sports Illustrated and the Detroit Sports Podcast. He and Huge talked about everything that went wrong for the Lions, gave their thought's on what needs to change moving forward, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Try our FREE burnout quiz.Grab your burnout workbook HERE. To sign up for our difficult conversations and workplace culture workshop go here.The journey of fighting cancer is so much more than just: finding out you have it and then getting treated.This week's episode is part 2 of our chat with Melanie Staudt, an incredible woman who overcame breast cancer and all of its challenges. For this week's episode Melanie will be sharing the challenges in recovery, post recovery and what happens when the cancer comes back.Melanie is 51 years old, lives in the US in Ohio and is married with two girls age 22 and 18.She was diagnosed with breast cancer in February 2021. It was three years of intensive healing and has had no evidence of disease for a year and a half. She continues to work on physical, mental and spiritual health and looks forward to life's next chapter. In this episode she shares:- Her second experience of cryoablation- The long term weight and energy of cancer treatment- Managing the fear and stress post cancer and how it impacts relationships- Learning to take care of herself and ask for and accept help- The story of how her doctor missed her active cancer- Using a trial treatment and having to get a mastectomy- Finding a lymph node in her sternum- What helped her to stop detaching from her body- Her lessons taken away after this experienceKey Quotes“I felt like a failure, I felt like I had made all the wrong decisions.”“People that haven't been through can't understand.”More about MelanieYou can contact Melanie via Facebook or Instagram.The pre surgery meditation link she mentioned is here. You can get involved with the podcast online On facebook in our community: https://www.facebook.com/groups/challengesthatchangeusOr on Instagram: @challengesthatchangeusIf you want to contact the podcast, email us here: support@challengesthatchangeus.comOr check out our website: www.Challengesthatchangeus.com If you want to find out more about what Ali does, check out her business via the website:http://www.trialtitudeperformance.com.au Hosted on Acast. See acast.com/privacy for more information.
Today on the show, we're talking about Michigan State Athletics, the High School Football Playoffs and the Road to Ford Field, and more as we were joined by some of our great guests. News broke right before the show started that MSU will have some wins vacated - so that's exactly what we talked about in the first hour. We kicked off the show talking with Jim Comparoni from SpartanMag.com so we could get his thought's on the news that just broke. He and Huge talked about why exactly this is happening, gave their thought's on what MSU is going to do moving forward, and more. We were then joined by Tim Staudt from Staudt on Sports. He gave us his initial thought's on everything that's happened in regard to MSU and their vacated wins. In our second hour, we talked about the High School Football Playoffs as we were joined by our High School Football insider Buck Geno. Buck and Huge talked about all of the Divisions and Regions throughout the State of Michigan, gave their thought's on all of the big match-ups happening this weekend, looked ahead to the Finals at Ford Field, and so much more. In our final hour, Huge and Buck Geno wrapped up their conversation in regards to the Road to Ford Field. We were then joined by Graham Couch from the Lansing State Journal. He gave us his thought's on MSU having to vacate their wins from 2022-2024, he gave his opinion on how MSU will bounce back from this, and more. We wrapped up the show talking with Mitch Lyons from Mitch Lyons Wealth. As a big MSU fan, we got his thought's on what happened with Michigan State today, and where they go from here. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today on the show, we're talking about Michigan State Athletics, the High School Football Playoffs and the Road to Ford Field, and more as we were joined by some of our great guests. News broke right before the show started that MSU will have some wins vacated - so that's exactly what we talked about in the first hour. We kicked off the show talking with Jim Comparoni from SpartanMag.com so we could get his thought's on the news that just broke. He and Huge talked about why exactly this is happening, gave their thought's on what MSU is going to do moving forward, and more. We were then joined by Tim Staudt from Staudt on Sports. He gave us his initial thought's on everything that's happened in regard to MSU and their vacated wins. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Tim Staudt from Staudt on Sports. He gave us his initial thought's on everything that's happened in regard to MSU and their vacated wins. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Try our FREE burnout quiz.Grab your burnout workbook HERE. To sign up for our difficult conversations and workplace culture workshop go here.Cancer has a devastating effect both on those it afflicts and those around them.For Melanie Staudt her cancer journey was full of challenges that often felt insurmountable.Melanie is 51 years old, lives in the US in Ohio and is married with two girls age 22 and 18.She was diagnosed with breast cancer in February 2021. It was three years of intensive healing and has had no evidence of disease for a year and a half. She continues to work on physical, mental and spiritual health and looks forward to life's next chapter. In this episode she shares:- Why she identifies most with a monarch butterfly- What happened for her in the early days leading up to breast cancer discovery- Getting her biopsy and preparing for bad news- How the initial bad news led to positivity in her life- The moment she got more bad news and her experience of detaching from her body- How she discussed her reservations about chemo with her husband- What her treatment options were and what she decided- When she saw a naturopathic doctor and her experience with craniosacral massage- When she got imaging done and got the all clearKey Quotes“I couldn't process anything, it was like I was out of my body.”“I probably spent between 20 and 40 hours a week researching breast cancer.”More about MelanieYou can contact Melanie via Facebook or Instagram.The pre surgery meditation link she mentioned is here. On facebook in our community: https://www.facebook.com/groups/challengesthatchangeusOr on Instagram: @challengesthatchangeusIf you want to contact the podcast, email us here: support@challengesthatchangeus.comOr check out our website: www.Challengesthatchangeus.com If you want to find out more about what Ali does, check out her business via the website:http://www.trialtitudeperformance.com.au Hosted on Acast. See acast.com/privacy for more information.
In our second hour, we were joined by Frank Schwab from Yahoo Sports. He and Huge talked about how the Lions have looked so far this season, talked about this weekend's game being a must-win game, discussed some of the storylines surrounding the rest of the NFL, and much more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about the start of Michigan Basketball's season, previewed tomorrow's game against Arkansas, and much more. We were then joined by Mike Kimber from Chat Sports. He and Huge gave their thought's on how this Sunday's game against the Commanders goes, talked about what the Lions need to do to bounce back, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about the start of Michigan Basketball's season, previewed tomorrow's game against Arkansas, and much more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
In our first hour, we were joined by former Detroit Lion Lomas Brown and Josh Garvey from Doeren Mayhew for our weekly "Inside the Lions" segment. During that time - Huge, Lomas, and Josh gave us their thought's on what went wrong in that loss to the Vikings, they talked about how the Lions and the Commanders stack up against each other, discussed the strengths and weaknesses of the Lions currently, gave their predictions on the game, and much more. Doug Skene from theWolverine.com then joined us to talk about Michigan Football. He told us how he feels about the Wolverines at this point in the season, talked about what improvements need to be made before Michigan takes on OSU, and much more. In our second hour, we were joined by Frank Schwab from Yahoo Sports. He and Huge talked about how the Lions have looked so far this season, talked about this weekend's game being a must-win game, discussed some of the storylines surrounding the rest of the NFL, and much more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about the start of Michigan Basketball's season, previewed tomorrow's game against Arkansas, and much more. We were then joined by Mike Kimber from Chat Sports. He and Huge gave their thought's on how this Sunday's game against the Commanders goes, talked about what the Lions need to do to bounce back, and more. In our final hour, we were joined by Scott Bischoff from the Detroit Lions Podcast. He and Huge talked about what went wrong in that loss to the Vikings last weekend, gave their thought's on the Offense and how John Morton has been doing, they looked ahead to Sunday's game against the Commanders, and much more. Tim Twentyman from DetroitLions.com then joined us. He gave us his opinion on what improvements he'd like to see before the Commanders game, Tim filled us in on the injuries on the team, and much more. We wrapped up the show with a "Moving Ferris Forward" interview as Huge spoke with Perrmella Harris who is Ferris States Head Cheer and Stunt Coach. She and Huge talked about the Cheer and Stunt team finishing fourth in the 2026 Great Lakes Valley Conference preseason coaches poll, she told us what went into putting the team together, talked about the impact on the gameday experience, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today on the show, we're talking about the Detroit Lions, Michigan and Michigan State Football, and more as we were joined by some of our great guests. Throughout our first hour we were joined in studio by our good friend Greg Heeres so he and Huge could break down the Lions loss to the Vikings yesterday and also talked about the World Series, and much more. We were also joined by Chris Balas from theWolverine.com so we could get his thought's on Michigan's win over Purdue. He and Huge talked about the what more they would've liked to see from Michigan in that game, talked about injuries, and more. In our second hour we were joined by former Major Leaguer John Vander Wal. He and Huge talked about a tough loss for the Lions yesterday and what needs to be fixed moving forward, talked about how fun the World Series was to watch, talked about the Tigers in the off-season, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He gave us his thought's on Michigan State's loss to Minnesota, talked about expectations moving forward, and more. Anthony Broome from theWolverine.com then joined us. He gave us his thought's on how Michigan looked in that win over Purdue, talked about expectations moving forward, and more. We talked about the Lions in our final hour as we were joined by Dave Birkett from the Detroit Free Press. He and Huge talked about yesterday's loss to the Vikings, gave their thought's on what needs improvement moving forward, and much more. Clayton Sayfie from theWolverine.com then joined us to talk about Michigan's win over Purdue. He and Huge talked about what improvements the team needs to make, looked ahead on the schedule, talked a little Michigan Basketball, and much more. We wrapped up the show talking with Steve Goff from the Lansing Sports Network. He and Huge talked about the Spartans and that rough loss to Minnesota, talked about what needs to change moving forward, talked some MSU Basketball, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
In our second hour we were joined by former Major Leaguer John Vander Wal. He and Huge talked about a tough loss for the Lions yesterday and what needs to be fixed moving forward, talked about how fun the World Series was to watch, talked about the Tigers in the off-season, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He gave us his thought's on Michigan State's loss to Minnesota, talked about expectations moving forward, and more. Anthony Broome from theWolverine.com then joined us. He gave us his thought's on how Michigan looked in that win over Purdue, talked about expectations moving forward, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He gave us his thought's on Michigan State's loss to Minnesota, talked about expectations moving forward, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
In our second hour, we were joined by Doug Karsch who is the voice of Michigan Football. He gave us his thought's on how the Wolverines looked in that win over MSU, talked about what he liked and disliked about that game, and much more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He gave us his thought's on how the Spartans looked in that loss, gave his opinion on how much longer Jonathan Smith is Coach, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He gave us his thought's on how the Spartans looked in that loss, gave his opinion on how much longer Jonathan Smith is Coach, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today on the show, we're talking all about Michigan beating Michigan State as we were joined by some of our great guests. We kicked off the show talking with Chris Balas from theWolverine.com so we could get his thought's on that win. He talked about what he liked in that game, gave his opinion on improvements he would like to see, looked ahead on the schedule, and more. Jim Comparoni from SpartanMag.com then joined us to give us some MSU perspective on Saturday's loss. He talked about some positives he saw, as well as all the negatives he noticed, he and Huge gave their thought's on how much longer Jonathan Smith is the Head Coach, and more. In our second hour, we were joined by Doug Karsch who is the voice of Michigan Football. He gave us his thought's on how the Wolverines looked in that win over MSU, talked about what he liked and disliked about that game, and much more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He gave us his thought's on how the Spartans looked in that loss, gave his opinion on how much longer Jonathan Smith is Coach, and more. In our final hour, we were joined by Anthony Broome from theWolverine.com to get his thought's on Michigan's win over MSU. He and Huge talked about how Michigan looked in that game, talked about some of the improvements they would like to see moving forward, and much more. We were then joined by Graham Couch from the Lansing State Journal. He and Huge broke down that loss to Michigan, talked about the poor Coaching, gave their thought's on Jonathan Smith, and more. We wrapped up the hour talking with Rob Bentley who is the voice of the Ferris State Bulldogs. He and Huge talked about a big win for Ferris over Grand Valley in the Anchor-Bone Classic. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
In our second hour, we were joined by Jim Brandstatter who is the former voice of Michigan Football. He and Huge talked about how this Michigan team has played this season, gave their thought's on what they need to do to beat MSU tomorrow, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He talked about what the Spartans need to do tomorrow to have a chance at beating Michigan, and more. We wrapped up the hour talking with John Borton from theWolverine.com about what he thinks will happen in that Michigan/Michigan State game. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He talked about what the Spartans need to do tomorrow to have a chance at beating Michigan, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today on the show, we're talking all about the big Michigan/Michigan State Rivalry game as we were joined by some of our great guests. We kicked off the show talking with Chris Balas from theWolverine.com so we could get his thought's on tomorrow's game. He talked about why he thinks Michigan will win tomorrow, gave his thought's on what challenges Michigan may have, and more. Jim Comparoni from Spartanmag.com then joined us to give us some Spartan perspective on Saturday's game. He filled us in on what he thinks the Spartans need to do to win, talked about some of their stand-out players, and more. We were then joined by Clayton Sayfie from theWolverine.com so he and Huge could preview Michigan/Michigan State. Clayton and Huge talked about what the keys to winning are for Michigan, and more. In our second hour, we were joined by Jim Brandstatter who is the former voice of Michigan Football. He and Huge talked about how this Michigan team has played this season, gave their thought's on what they need to do to beat MSU tomorrow, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He talked about what the Spartans need to do tomorrow to have a chance at beating Michigan, and more. We wrapped up the hour talking with John Borton from theWolverine.com about what he thinks will happen in that Michigan/Michigan State game. In our final hour, Doug Skene from theWolverine.com joined us to talk Michigan/Michigan State. He talked about where he feels confident in the Wolverines as well as what worries him, talked about what this team needs to do to beat the Spartans, and more. We were then joined by Steve Goff from the Lansing Sports Network. He talked about what he likes about this MSU team, talked about what they need to do to win, and much more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Chris Balas theWolverine.com in our second hour so he and Huge could talk about Michigan Football. They gave their thought's on how the team played in that win against Washington, looked ahead to this weekend's game against MSU, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about Michigan State's loss to Indiana, looked ahead to the game against Michigan, and more. We wrapped up the hour talking with Greg Heeres about the Detroit Lions. He talked about what the Lions need to do to win, gave his prediction, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about Michigan State's loss to Indiana, looked ahead to the game against Michigan, and more. We wrapped up the hour talking with Greg Heeres about the Detroit Lions. He talked about what the Lions need to do to win, gave his prediction, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today we're broadcasting from the Alpine Golf Club in Comstock Park as they hosted our Huge Rivalry Cup along with the North Kent Golf Course in Rockford. Throughout the show, we were joined by some of the great folks connected to Alpine and North Kent so we could hear about some of the exciting things they have to offer. We were also joined by some of our great guests to talk about the Detroit Lions, Michigan and Michigan State Football, and more. We kicked off the show talking about the Lions as Tim Twentyman from DetroitLions.com joined us. He and Huge previewed tonight's game against Tampa Bay, talked about the key things the Lions need to do to win, and more. We were then joined by Frank Schwab from Yahoo Sports. He gave us his thought's on how the Lions game goes tonight, talked about some of the storylines surrounding the NFL, and more. We wrapped up the hour talking with Skip Connolly who is the Head Superintendent at the Alpine Golf Club. He talked about some of the things they're doing to improve the course, talked about plans for the future, and more. We were joined by Chris Balas theWolverine.com in our second hour so he and Huge could talk about Michigan Football. They gave their thought's on how the team played in that win against Washington, looked ahead to this weekend's game against MSU, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about Michigan State's loss to Indiana, looked ahead to the game against Michigan, and more. We wrapped up the hour talking with Greg Heeres about the Detroit Lions. He talked about what the Lions need to do to win, gave his prediction, and more. In our final hour, we were joined by Nic Lapienski who is the Owner of the Alpine and North Kent Golf Courses. He updated us on how things are going at both courses, talked about improvements they've been making, talked about the food at their Par & Plate eatery, and more. We were then joined by Jim Comparoni from SpartanMag.com to talk MSU Football. He gave his thought's on the loss to Illinois, talked about what the Spartans need to do to beat Michigan, and more. Clayton Sayfie from theWolverine.com then joined us. He talked about that win over Washington, previewed this weekend's game against MSU, and more. We were then joined by Jason Sachez who is the General Manager at the Alpine Golf Club. He talked about all of the growth they've had over the past 2 years, talked about what's to come, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode of the Epigenetics Podcast, we talked with Ryan Corces from the Gladstone Institutes about his work on the impact of chromatin architecture on Alzheimer's and Parkinson's Disease. The discussion begins in discussing he start of Dr. Corces research career and he shares his groundbreaking findings in acute myeloid leukemia (AML), demonstrating how mutations occurring in hematopoietic stem cells lead to the evolution of this disease. He emphasizes the pivotal role of epigenetic modifiers and how these insights steered his focus towards epigenetic research. As the conversation progresses, Dr. Corces covers his transition to a postdoctoral role, emphasizing his collaborative work employing the ATAC-seq technique. He details how refinements to this protocol not only improved data quality but also paved the way for more expansive research within the fields of hematology and cancer genetics. Additionally, he discusses his excitement for developing new computational tools for single-cell analysis, aiming to address the critical challenge of distinguishing between cellular states effectively. The episode also explores the fascinating intersection of Alzheimer's and Parkinson's diseases. Dr. Corces explains the rationale for studying both conditions simultaneously, shedding light on the shared and divergent pathological features that emerge in patients. He argues for the importance of understanding mixed pathologies, which reflect the reality for many individuals diagnosed with these neurodegenerative diseases. References Corces, M. R., Trevino, A. E., Hamilton, E. G., Greenside, P. G., Sinnott-Armstrong, N. A., Vesuna, S., Satpathy, A. T., Rubin, A. J., Montine, K. S., Wu, B., Kathiria, A., Cho, S. W., Mumbach, M. R., Carter, A. C., Kasowski, M., Orloff, L. A., Risca, V. I., Kundaje, A., Khavari, P. A., Montine, T. J., … Chang, H. Y. (2017). An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nature methods, 14(10), 959–962. https://doi.org/10.1038/nmeth.4396 Corces, M. R., Granja, J. M., Shams, S., Louie, B. H., Seoane, J. A., Zhou, W., Silva, T. C., Groeneveld, C., Wong, C. K., Cho, S. W., Satpathy, A. T., Mumbach, M. R., Hoadley, K. A., Robertson, A. G., Sheffield, N. C., Felau, I., Castro, M. A. A., Berman, B. P., Staudt, L. M., Zenklusen, J. C., … Chang, H. Y. (2018). The chromatin accessibility landscape of primary human cancers. Science (New York, N.Y.), 362(6413), eaav1898. https://doi.org/10.1126/science.aav1898 Corces, M. R., Trevino, A. E., Hamilton, E. G., Greenside, P. G., Sinnott-Armstrong, N. A., Vesuna, S., Satpathy, A. T., Rubin, A. J., Montine, K. S., Wu, B., Kathiria, A., Cho, S. W., Mumbach, M. R., Carter, A. C., Kasowski, M., Orloff, L. A., Risca, V. I., Kundaje, A., Khavari, P. A., Montine, T. J., … Chang, H. Y. (2017). An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nature methods, 14(10), 959–962. https://doi.org/10.1038/nmeth.4396 Sant, C., Mucke, L., & Corces, M. R. (2025). CHOIR improves significance-based detection of cell types and states from single-cell data. Nature genetics, 57(5), 1309–1319. https://doi.org/10.1038/s41588-025-02148-8 Related Episodes ATAC-Seq, scATAC-Seq and Chromatin Dynamics in Single-Cells (Jason Buenrostro) Multiple challenges of ATAC-Seq, Points to Consider (Yuan Xue) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com
We talked about Michigan Football in our second hour as Clayton Sayfie from theWolverine.com joined us. He and Huge talked about last weekend's loss to USC and what weaknesses they're noticing with the team, talked about the poor coaching they've noticed from Sherrone Moore, gave their thought's on how Bryce Underwood has been playing, previewed this weekend's game against Washington, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about the current state of Michigan State Football, gave their thought's on if Jonathan Smith is on the hot seat, and more. Keith Langlois from DetroitPistons.com then joined us to fill us in on what the off-season was like for the Pistons, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about the current state of Michigan State Football, gave their thought's on if Jonathan Smith is on the hot seat, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today on the show, we're talking about the Detroit Lions, Michigan and Michigan State Football, and more as we were joined by some of our great guests. We kicked off the show talking about the Detroit Lions as we were joined by Dan Miller, who is the voice of the Lions. He and Huge looked back at that loss the Chiefs Sunday night, talked about what improvements they would like to see, discussed injuries, looked ahead to Tampa Bay on Monday, and more. We were then joined by Bill's friend Mike Cupples so he and Huge could talk about their late friend Doug "Wabs" Wabeke getting inducted into the Grand Rapids Sports Hall of Fame last night, and the impact Doug made on their lives, and many others. We talked about Michigan Football in our second hour as Clayton Sayfie from theWolverine.com joined us. He and Huge talked about last weekend's loss to USC and what weaknesses they're noticing with the team, talked about the poor coaching they've noticed from Sherrone Moore, gave their thought's on how Bryce Underwood has been playing, previewed this weekend's game against Washington, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about the current state of Michigan State Football, gave their thought's on if Jonathan Smith is on the hot seat, and more. Keith Langlois from DetroitPistons.com then joined us to fill us in on what the off-season was like for the Pistons, and more. In our final hour, we were joined by Mitch Lyons from Mitch Lyons Wealth. He and Huge gave their thought's on Michigan State Football and Jonathan Smith, discussed the end of the Tigers season, talked about the Lions loss to the Chiefs, looked ahead to Tampa Bay, and Mitch told us how he can help with your retirement. Anthony Broome from theWolverine.com then joined us to talk Michigan Football. He and Huge gave their thought's on what changes need to be made with the Wolverines, talked about Sherrone Moore, looked ahead to Washington, talked a little Michigan Basketball, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Glenn goes through some of the lessons he shared during his Turning Point USA event at the University of North Dakota. Glenn speaks with a young athlete named Frances Staudt, who, after refusing to play basketball with a male identifying as a woman, required security to speak at an event advocating for the protection of women's sports. “Mount Doom” co-author Paul List discusses what J.R.R. Tolkien predicted about artificial intelligence and transhumanism in “The Lord of the Rings.” Learn more about your ad choices. Visit megaphone.fm/adchoices
Glenn starts the show by reading a statement made by Christopher Rufo regarding America's ongoing support for the nation of Israel. Is criticizing Israel equated to anti-Semitism? Glenn argues no, explaining why supporters of Israel must defend their position from the perspective of American interests. Glenn also calls out the evil of Islamism and the threat it poses to Israel and America. Glenn goes through some of the lessons he shared during his Turning Point USA event at the University of North Dakota. Cut this generation some slack, Glenn argues, because he sees something happening within them that gives him hope. Rutgers University Turning Point charter members Ava Kwan and Megyn Doyle join to discuss the backlash they've received since authoring a petition to remove a professor with the nickname “Dr. Antifa.” Glenn speaks with a young athlete named Frances Staudt, who, after refusing to play basketball with a male identifying as a woman, required security to speak at an event advocating for the protection of women's sports. “Mount Doom” co-author Paul List discusses what J.R.R. Tolkien predicted about artificial intelligence and transhumanism in “The Lord of the Rings.” Learn more about your ad choices. Visit megaphone.fm/adchoices
Today on the show, we're talking all about the Detroit Tigers as they're taking on the Cleveland Guardians in game one of the Playoffs. Throughout the first half of the show, we were joined by our good friend Greg Heeres so he and Huge could watch the Tigers game in progress, give their thought's on what's happening in the game, and much more. In our second hour, we were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about a big win for the Tigers today, gave their thought's on how tomorrow's game goes and if the Tigers can win the series, and much more. We wrapped up the hour talking with Ben Bosscher from our affiliate 100.9 the Mitt in the Great Lakes Bay Region. We got his thought's on the Tigers win over the Guardians, discussed the path moving forward, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about a big win for the Tigers today, gave their thought's on how tomorrow's game goes and if the Tigers can win the series, and much more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Today on the show, we're talking all about the Detroit Tigers as they're taking on the Cleveland Guardians in game one of the Playoffs. Throughout the first half of the show, we were joined by our good friend Greg Heeres so he and Huge could watch the Tigers game in progress, give their thought's on what's happening in the game, and much more. In our first hour, we were also joined by former Major Leaguer John Vander Wal so we could also get his thought's on game one in progress. At the end of the hour, we were joined by Matt Cook who is the Vice President of Community Relations for Lake Michigan Credit Union. He and Huge talked about our new partnership, LMCU's connection to Sports and the community, and more. In our second hour, we were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about a big win for the Tigers today, gave their thought's on how tomorrow's game goes and if the Tigers can win the series, and much more. We wrapped up the hour talking with Ben Bosscher from our affiliate 100.9 the Mitt in the Great Lakes Bay Region. We got his thought's on the Tigers win over the Guardians, discussed the path moving forward, and more. In our final hour, we were joined by Matt Shepard from X's and Bro's in the Mornings so he and Huge could break down the Tigers win over the Guardians today. They talked about what they liked most from that game, talked about how they think the rest of the Series will go, discussed what improvements the team still needs to make, and more. We then continued the conversation as Alex Urban from the "Eat 'em Up: Detroit Tigers Podcast" joined us. He told us about what he liked most from that win, previewed the rest of the series, and more. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge gave their thought's on how MSU will do against USC and if there's a chance that MSU wins that game, they talked a little about Ferris State Football, and more. See omnystudio.com/listener for privacy information.
Today on the show we're talking about Michigan and Michigan State Football, the Detroit Lions and more as we were joined by some of our great guests. We kicked off the show talking with the former voice of Michigan Football, Jim Brandstatter. He and Huge gave their opinions on how Michigan will do against Nebraska tomorrow night, talked about some of the big playmakers on the team, and much more. We talked more about Michigan/Nebraska as Chris Balas from theWolverine.com joined us. He and Huge talked about what they expect out of Bryce Underwood in that game, gave their thought's on the strengths and weaknesses of the team, and more. We then talked with Jim Comparoni from SpartanMag.com about MSU/USC. He gave his thought's on what MSU would need to do to win that game, and more. We were then joined by Kyle Crooks who is the radio voice of the Nebraska Huskers. He gave his thought's on how Michigan and Nebraska stack up, looked around the rest of the Big Ten, and more. We then had a "Moving Ferris Forward" interview spoke with Rob Bentley, who is the voice of Ferris State Football. He and Huge previewed Ferris State's game against Rio Grande, talked about some of the fresh faces on the team and the impact they're making, and more. In our second hour, we were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge gave their thought's on how MSU will do against USC and if there's a chance that MSU wins that game, they talked a little about Ferris State Football, and more. We were then joined by Mitch Lyons from Mitch Lyons Wealth. He and Huge talked about how good the Lions looked in that win over the Bears, previewed the game against the Ravens, talked about MSU/USC, and told us how he can help with your retirement. We wrapped up the hour talking with Ryan Abraham from USCFootball.com about the MSU/USC match up. Ryan told us what he likes about this USC team, gave his thought's on the Spartans from a Trojan perspective, and more. In our final hour, Huge talked about the Detroit Tigers as they've been playing some really poor baseball lately. He was also joined by Steve Sipple who is a Nebraska insider for On3 and is a co-host of “Early Break” on 93.7 The Ticket in Nebraska. He joined us so he and Huge could preview that Michigan/Nebraska game, they talked about the strengths and weakness of both teams, gave their thought's on how that game will go, and more.See omnystudio.com/listener for privacy information.
In our second hour, we were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge gave their thought's on how MSU will do against USC and if there's a chance that MSU wins that game, they talked a little about Ferris State Football, and more. We were then joined by Mitch Lyons from Mitch Lyons Wealth. He and Huge talked about how good the Lions looked in that win over the Bears, previewed the game against the Ravens, talked about MSU/USC, and told us how he can help with your retirement. We wrapped up the hour talking with Ryan Abraham from USCFootball.com about the MSU/USC match up. Ryan told us what he likes about this USC team, gave his thought's on the Spartans from a Trojan perspective, and more.See omnystudio.com/listener for privacy information.
#875. Kaitlyn sits down with Rachael Staudt from Hulu's new show Are You My First? for her very first interview since the season wrapped — and with no reunion yet, this is the conversation fans have been waiting for!!From never-before-heard behind-the-scenes moments to the burning questions the internet can't stop asking — what really happened after filming? Where do things stand with Michael? Who's still close, who's not, and what shocked Rachael the most when the cameras stopped rolling?Plus, Kaitlyn dives into Rachael's personal journey with vaginismus and the exciting new chapter she's writing… literally.If the finale left you with questions, you'll definitely want to tune in now!If you're LOVING this podcast, please follow and leave a rating and review below! PLUS, FOLLOW OUR PODCAST INSTAGRAM HERE!Thank you to our Sponsors! Check out these deals!Apartments.com: The place to find a place!Better Help: Off the vine listeners get 10% off their first month at betterhelp.com/vineQuince: Go to QUINCE.com/vine for free shipping on your order and 365-day returns.Progressive: Visit Progressive.com to see if you could save on car insurance.EPISODE HIGHLIGHTS: 4:53 – How Rachael got cast on Are You My First?16:46 – Where things stand today with Michael.50:45 – Rachael opens up about her journey with vaginismus.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today on the show, we're talking about Michigan and Michigan State Football, the Detroit Lions, and more as we were joined by some of our great guests. We kicked off the show talking about Michigan State Football as we were joined by Graham Couch from the Lansing State Journal. He and Huge talked about what they've liked from the Spartans in the first two games, talked about the weaknesses they see, looked ahead to this weekend's game against Youngstown State, and much more. Anthony Broome from theWolverine.com then joined us to give his opinion on how Michigan looked against Oklahoma this past weekend. He and Huge talked about how Bryce Underwood played, talked about where this team needs to improve, and much more. We were joined by Clayton Sayfie from theWolverine.com in our second hour so we could get his thought's on how Michigan looked against Oklahoma. He and Huge talked about how Bryce looked in that game, Huge and Clayton previewed this weekend's game against CMU, talked about Sherrone Moore and the job he's done so far, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about how MSU looked in that win over Boston College, previewed their next game against Youngstown State, talked a little about the Lions, and more. In our final hour, we were joined by Scott Bischoff from the Detroit Lions Podcast. He and Huge talked about that loss to the Packers over the weekend, broke down all of the negatives they saw, gave their thought's on why something just seems off with this team, looked ahead to this Sunday's game against the Bears, and more. We were then joined by George Blaha who is the voice of Michigan State Football. He was just inducted into the Basketball Hall of Fame, so he told us what the induction ceremony was like for him, talked about some of his favorite Broadcasting moments, talked about the Pistons, and more.See omnystudio.com/listener for privacy information.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about how MSU looked in that win over Boston College, previewed their next game against Youngstown State, talked a little about the Lions, and more.See omnystudio.com/listener for privacy information.
We were joined by Clayton Sayfie from theWolverine.com in our second hour so we could get his thought's on how Michigan looked against Oklahoma. He and Huge talked about how Bryce looked in that game, Huge and Clayton previewed this weekend's game against CMU, talked about Sherrone Moore and the job he's done so far, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about how MSU looked in that win over Boston College, previewed their next game against Youngstown State, talked a little about the Lions, and more.See omnystudio.com/listener for privacy information.
unDivided brings you a special interview series, celebrating important "Truth Tellers" from all sides of politics and culture. On this episode: Washington state high school athletes Frances Staudt and Ahnaleigh Wilson are standing up for themselves – and for girls everywhere.
In our second hour, we were joined by Jim Brandstatter who is the former the voice of Michigan Football. He gave us his thought's on how Michigan looked in that game against New Mexico, talked about how Bryce Underwood looked, talked about some of the big playmakers on the team, and much more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. Tim and Huge talked about what they liked from the Spartans in the game against Western, gave their thought's on where things need to improve moving forward, and more. We were then joined by Mitch Lyons from Mitch Lyons Wealth so we could get his first impressions on the Spartans. He told us his expectations going into that game, talked about where this team looked good as well as what needs work, he told us how he can help with your retirement, and more.See omnystudio.com/listener for privacy information.
We were joined by Tim Staudt from Staudt on Sports in Lansing. Tim and Huge talked about what they liked from the Spartans in the game against Western, gave their thought's on where things need to improve moving forward, and more. See omnystudio.com/listener for privacy information.
Today on the show, we're talking about Michigan and Michigan State Football, the Detroit Lions, and more as we were joined by some of our great guests. We kicked off the show talking about Michigan State's win over Western as Jim Comparoni from SpartanMag.com joined us. He and Huge talked about the positives and negatives they noticed in that game, gave their thought's on where this team is better, looked ahead to this weekend's game against Boston College, and more. Chris Balas from theWolverine.com then joined us to give his thought's on Michigan's win over New Mexico, he and Huge talked about recent news coming out in regards to a supposed mole in the Michigan Football program, and more. In our second hour, we were joined by Jim Brandstatter who is the former the voice of Michigan Football. He gave us his thought's on how Michigan looked in that game against New Mexico, talked about how Bryce Underwood looked, talked about some of the big playmakers on the team, and much more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. Tim and Huge talked about what they liked from the Spartans in the game against Western, gave their thought's on where things need to improve moving forward, and more. We were then joined by Mitch Lyons from Mitch Lyons Wealth so we could get his first impressions on the Spartans. He told us his expectations going into that game, talked about where this team looked good as well as what needs work, he told us how he can help with your retirement, and more. In our final hour, Chris Balas from theWolverine.com joined us again to go further in depth into that Michigan/New Mexico game. Doug Skene from theWolverine.com then joined us to give his thought's on how the Wolverines played on Saturday. Doug gave us his first impressions on Bryce Underwood, talked about the Offensive and Defensive lines, and more. We were then joined by Steve Goff from the Lansing Sports Network. He gave us his thought's on how the Spartans looked in that win over Western, talked about how Aidan Chiles looked, talked about what needs improvement, and more. We wrapped up the show talking with Clayton Sayfie from theWolverine.com about Michigan. He gave us his thought's on how Michigan looked, talked about how Bryce Underwood looked, and much more.See omnystudio.com/listener for privacy information.
In our second hour, we were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about the Spartans as they're set to take on Western this Friday night. They talked about expectations for the team this season, and also talked about the Lions, and more. We were then joined by Anthony Broome from theWolverine.com to talk Michigan Football. He gave his thought's on how Underwood will do in his first season, they talked about their expectations for him and the team, and more. We wrapped up the second hour talking with Hope Football player Seth Luhmann. He talked about why he wanted to play at Hope, talked about the team and the amazing community at Hope, and more. See omnystudio.com/listener for privacy information.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about the Spartans as they're set to take on Western this Friday night. They talked about expectations for the team this season, and also talked about the Lions, and more. See omnystudio.com/listener for privacy information.
Today we're broadcasting from Hope College as the start of the Football season is just around the corner. Throughout the show, we were joined by Head Coach Peter Stuursma and some of his players so we could hear about their team, culture, and more. We were also joined by some of our great guests to talk about the Tigers, Michigan and Michigan State Football, and more. We kicked off the show talking with Coach Stuursma about how last season went for his team, talked about some of the players that are making an impact on the team, talked about the importance of culture, and much more. We were then joined by Clayton Sayfie from theWolverine.com so we could look ahead to the start of Michigan's season. He and Huge talked about Bryce Underwood being named the starting QB, talked about expectations, talked about the Big Ten, and more. We wrapped up the hour talking with Hope Football player Austin Harvey. He talked about why Hope is special to him, talked about the type of team they've been building, and more. In our second hour, we were joined by Tim Staudt from Staudt on Sports in Lansing. He and Huge talked about the Spartans as they're set to take on Western this Friday night. They talked about expectations for the team this season, and also talked about the Lions, and more. We were then joined by Anthony Broome from theWolverine.com to talk Michigan Football. He gave his thought's on how Underwood will do in his first season, they talked about their expectations for him and the team, and more. We wrapped up the second hour talking with Hope Football player Seth Luhmann. He talked about why he wanted to play at Hope, talked about the team and the amazing community at Hope, and more. In our final hour, we were joined by Graham Couch from the Lansing State Journal. He and Huge talked about MSU Football, talked about how the off-season went for Coach Smith and the team, discussed their expectations for the season, looked around the rest of the Big Ten, and more. Doug Skene from theWolverine.com then joined us to talk Michigan Football. He and Huge looked ahead to Saturday's game against New Mexico, gave their thought's on Bryce Underwood, and more. We were then joined by Greg Heeres who is one of our Tigers insiders. He and Huge talked about how Skubal pitched in that loss to the Athletics last night. We wrapped up the show talking with Coach Peter Stuursma again as they just wrapped up practice.See omnystudio.com/listener for privacy information.
Today we're broadcasting from American Dunes as the Grand Rapids Griffins Youth Foundation is hosting their Annual Golf Outing to raise funds for kids. Throughout the show, we were joined by some of our great guests to talk about the Detroit Tigers, Detroit Lions, Michigan and Michigan State Athletics, and more as we were joined by some of our great guests. We kicked off the show talking about the Tigers as we were joined by former Major Leaguer John Vander Wal. He and Huge talked about how the series went against the Twins, previewed the series against the Astros, gave their thought's on the pitching and hitting, talked about expectations moving forward, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He gave us his opinion on the NCAA/Michigan situation, gave his thought's on what happens moving forward, and more. We talked about the Detroit Lions in our second hour as Jeff Risdon from Lions Wire joined us. He and Huge talked about how the Lions looked in that preseason game against the Dolphins, talked about the backup QB situation and how Kyle Allen seems to be the guy, talked about other players that made an impression in that game, and much more. We were then joined by Chris Balas from theWolverine.com to get an update on Michigan and the NCAA. He told us everything he's heard over the weekend and also updated us on an injury on the Michigan Football team, and more. In our final hour, we were joined by Doug Bell who is the GM at American Dunes. He told us about some of the things they've got going on, filled us in on the Folds of Honor Collegiate happening in September, talked about Patriot Golf Days, and more. We were then joined by David Gregory who is a Lawyer and NFLPA Certified Sports Agent for Bullrush Sports. He and Huge talked about what's happened in regards to the NCAA sanctions against Michigan, talked about Harbaugh's and Stalions Lawyers firing back at the NCAA, and much more. We were then joined by John Maakaron from Sports Illustrated and the Detroit Sports Podcast. He gave us his thought's on how the Lions looked against the Dolphins, gave his thought's on Hendon Hooker and Kyle Allen, looked ahead to this weekend's game against the Texans, and more. We wrapped up the show talking with Bruce Hungerford, who is the Head Coach of the East Grand Rapids Girls Volleyball program. They're having an outdoor Volleyball match on the EGR Football field this Wednesday August 20th. Bruce filled us in on why they're doing this, everything they'll have to offer, and more.See omnystudio.com/listener for privacy information.
We were joined by Tim Staudt from Staudt on Sports in Lansing. He gave us his opinion on the NCAA/Michigan situation, gave his thought's on what happens moving forward, and more. See omnystudio.com/listener for privacy information.
Today we're broadcasting from American Dunes as the Grand Rapids Griffins Youth Foundation is hosting their Annual Golf Outing to raise funds for kids. Throughout the show, we were joined by some of our great guests to talk about the Detroit Tigers, Detroit Lions, Michigan and Michigan State Athletics, and more as we were joined by some of our great guests. We kicked off the show talking about the Tigers as we were joined by former Major Leaguer John Vander Wal. He and Huge talked about how the series went against the Twins, previewed the series against the Astros, gave their thought's on the pitching and hitting, talked about expectations moving forward, and more. We were then joined by Tim Staudt from Staudt on Sports in Lansing. He gave us his opinion on the NCAA/Michigan situation, gave his thought's on what happens moving forward, and more. See omnystudio.com/listener for privacy information.
Did you know that St. Francis of Assisi observed a special season of prayer, fasting, and penance starting on the Feast of the Assumption and ending on the Feast of St. Michael the Archangel? It's called St. Michael's Lent, and it's making a powerful comeback among Catholics seeking spiritual renewal. In this episode, Fr. Edward Looney speaks with Dr. Jared Staudt, theologian and formation leader with Exodus 90, about the history, spirituality, and modern revival of St. Michael's Lent. Together they explore: • How St. Francis of Assisi first observed St. Michael's Lent • Why it begins on August 15 (Assumption) and ends on September 29 (Michaelmas) • Whether other Catholic saints followed this tradition • How it compares to the Lenten season and whether feast days are penance-free • Practical ideas for living St. Michael's Lent today • What Exodus 90 is offering to help men spiritually engage with this season Whether you're looking for a way to deepen your Catholic faith, embrace penance and prayer, or just curious about this revived Catholic tradition, this episode is for you.