Podcasts about Engineering

Is math truly universal—or just human? Explore how alien minds might think, count, and reason in ways we don't recognize as mathematics at all.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video The Future of Interstellar Communication: https://nebula.tv/videos/isaacarthur-chronoengineering-manipulating-time-as-technologyCheck out Joe Scott's Oldest & Newest: https://nebula.tv/videos/joescott-oldest-and-newest-places-on-earth?ref=isaacarthur

Is math truly universal—or just human? Explore how alien minds might think, count, and reason in ways we don't recognize as mathematics at all.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video The Future of Interstellar Communication: https://nebula.tv/videos/isaacarthur-chronoengineering-manipulating-time-as-technologyCheck out Joe Scott's Oldest & Newest: https://nebula.tv/videos/joescott-oldest-and-newest-places-on-earth?ref=isaacarthur

Send a textIn this episode of BetaTalk, Nathan welcomes back engineer and coder James Twallin to discuss the technical nuances of the UK's energy transition. While industry debates are often binary, this conversation focuses on objective data regarding gas infrastructure, the physics of high mass heritage buildings, and the importance of real world boiler monitoring for hydronic heat pump success.Key Topics Discussed:The "Invisible" Gas Leak Problem: James reveals his research into the UK's gas network. He explains how current energy policy and EPC ratings often ignore upstream methane leaks. Using Freedom of Information data, he highlights the prevalence of leaks in ancient cast iron mains featuring 19th century archaeological engineering.Decarbonising Heritage Buildings: A deep dive into a 200 year old stone church project. James explains why steady state modelling fails in these environments and how a physics based approach allowed for a successful, intermittent air to air heat pump installation by leveraging the building's thermal mass.Optimising Hydronic Transitions: Nathan and James discuss a new monitoring device designed to track existing boiler behaviour. By gathering data on flow temperatures and cycling, engineers can create a more accurate blueprint for future heat pump performance.Technical Correction During the recording, a Bosch study involving 4,000 units was discussed. While mentioned as a heat pump survey in the audio, Nathan would like to clarify that the study actually monitored 4,000 gas boilers. Thanks to the Patrons of the Guild of Master Heat Engineers who help make these podcasts possible Support the showLearn more about heat pump heating by followingNathan on Linkedin, Twitter and BlueSky

We kick things off in FOLLOW UP with the ongoing "nuclear war" between Automattic and WP Engine, where discovery has revealed Matt Mullenweg's alleged hit list of competitors and a desperate attempt to bully payment processors—because nothing says "open source" like an eight-percent royalty shakedown. Meanwhile, the Harvard Business Review confirmed what we already knew: AI isn't reducing our work; it's just compressing it until we're all working through lunch and burning out faster while Polymarket turns our collective brain rot into a literal "attention market" where you can bet on Elon's mindshare.Transitioning to IN THE NEWS, Elon has officially pivoted SpaceX from Mars to the Moon, presumably because building a "self-growing lunar city" is easier than admitting the Red Planet is hard, though his xAI all-hands rant about "ancient alien catapults" suggests he's been staring at the sun too long. Between X allegedly taking blue-check lunch money from sanctioned Iranian leaders, Meta facing trials for creating "predator-friendly hunting grounds," and Russia finally pulling the plug on WhatsApp, the internet is looking more like a digital dumpster fire than ever. Add in Discord leaking 70,000 government IDs, OpenAI shoving ads into ChatGPT while safety researchers flee the building like it's on fire, and a "cognitive debt" crisis eroding our ability to think, and you've got a recipe for a tech-induced psychosis that even crypto-funded human trafficking can't outpace.In MEDIA CANDY, we're wondering about the soft-core porn intro in the latest Star Trek: Starfleet Academy while Apple buys the total rights to Severance for seventy million dollars—because in-house production is the only way to keep those ballooning budgets under control. Super Bowl trailer season gave us a glimpse of The Mandalorian and Grogu and a Project Hail Mary teaser, while Babylon 5 has finally landed on YouTube for free, proving that even 90s serialized sci-fi eventually finds its way to the clearance bin.Over in APPS & DOODADS, Meta Quest is nagging us for our birthdays like a needy relative, while Roblox had to scrub a mass-shooting simulator—because "AI plus human safety teams" is apparently just code for "we missed it until it hit the forums." Ring's Super Bowl ad for "Search Party" accidentally terrified everyone by revealing a mass surveillance network for pets that's a slippery slope toward a police state, and Waymo is now paying DoorDashers ten bucks just to walk over and close the car doors that autonomous tech still can't figure out.Wrapping up with THE DARK SIDE WITH DAVE, we dive into the Mandalorian Hasbro reveal where Sigourney Weaver's action figure comes with no accessories because her existence is enough of a flex. We explore the grim reality of "RentAHuman," where humans are paid pittance to pretend AI agents are actually doing work, and look at "Trash Talk Audio," which sells a $125 microphone made out of a literal old telephone for that authentic Gen-X "get off the line, I'm expecting a call" aesthetic. From Marcia Lucas finally venting about the prequels and a rare book catalog specifically for our aging generation, we're reminded that while the future is a chaotic mess of "GeoSpy" AI and corporate reshuffling at Disney, at least we still have our cynical memories and some free versions of Roller Coaster Tycoon to keep us from losing it completely.Sponsors:CleanMyMac - Get Tidy Today! Try 7 days free and use code OLDGEEKS for 20% off at clnmy.com/OLDGEEKSDeleteMe - Get 20% off your DeleteMe plan when you go to JoinDeleteMe.com/GOG and use promo code GOG at checkout.Private Internet Access - Go to GOG.Show/vpn and sign up today. For a limited time only, you can get OUR favorite VPN for as little as $2.03 a month.SetApp - With a single monthly subscription you get 240+ apps for your Mac. Go to SetApp and get started today!!!1Password - Get a great deal on the only password manager recommended by Grumpy Old Geeks! gog.show/1passwordShow notes at https://gog.show/733FOLLOW UPAutomattic planned to target 10 competitors with royalty fees, WP Engine claims in new filingAI Doesn't Reduce Work—It Intensifies ItPolymarket To Offer Attention Markets In Partnership With Kaito AIIsrael Arrests Members of Military for Placing Polymarket Bets Using Inside Information on Upcoming StrikesIN THE NEWSUnable to Reach Mars, Musk Does the Most Musk Thing PossibleWe'll Find the Remnants of Ancient Alien Civilizations': Read Musk's Gibberish Rant from His xAI All-Hands MeetingElon Musk's X Appears to Be Violating US Sanctions by Selling Premium Accounts to Iranian LeadersMeta Faces Two Key Trials That Could Change Social Media ForeverWhatsApp is now fully blocked in RussiaRussia is restricting access to Telegram, one of its most popular social media apps. Here's what we knowDOJ may face investigation for pressuring Apple, Google to remove apps for tracking ICE agentsDiscord Launches Teen-by-Default Settings GloballyDiscord says hackers stole government IDs of 70,000 usersFree Tool Says it Can Bypass Discord's Age Verification Check With a 3D ModelTesting ads in ChatGPTOpenAI Researcher Quits, Warns Its Unprecedented ‘Archive of Human Candor' Is DangerousOpenAI Fires Top Safety Exec Who Opposed ChatGPT's “Adult Mode”Anthropic AI Safety Researcher Warns Of World ‘In Peril' In ResignationMusk's xAI loses second co-founder in two daysAmerica Isn't Ready for What AI Will Do to JobsMonologue: No, Something Big Isn't ComingThe Scientist Who Predicted AI Psychosis Has a Grim Forecast of What's Going to Happen NextCrypto-Funded Human Trafficking Is ExplodingMEDIA CANDYShrinkingStar Trek: Starfleet AcademyPoor ThingsProject Hail Mary | Final TrailerMinions & Monsters | Official TrailerDisclosure Day | Big Game SpotThe Mandalorian and Grogu | A New Journey Begins | In Theaters May 22Babylon 5 Is Now Free to Watch On YouTubeApple acquires all rights to ‘Severance,' will produce future seasons in-houseOptimizing your TVAPPS & DOODADSTumbler Ridge Shooter Created Mall Shooting Simulator in RobloxHere's how to disable Ring's creepy Search Party featureWaymo Is Getting DoorDashers to Close Doors on Self Driving CarsTikTok US launches a local feed that leverages a user's exact locationApple just released iOS 26.3 alongside updates for the Mac, iPad and Apple WatchTHE DARK SIDE WITH DAVEDave BittnerThe CyberWireHacking HumansCaveatControl LoopOnly Malware in the BuildingWe Call It ImagineeringYour First Look at Hasbro's 'Mandalorian and Grogu' Figures Is Here (Exclusive)I Tried RentAHuman, Where AI Agents Hired Me to Hype Their AI StartupsTrash Talk AudioRoger Reacts to Star Wars - A New HopeMarcia Lucas Finally Speaks Out | Icons Unearthed: Unplugged (FULL INTERVIEW)What's wrong with the prequels?Rare Books, Gen X editionGeoSpyCLOSING SHOUT-OUTSRobert Tinney, who painted iconic Byte magazine covers, RIPBud CortSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Balaji Srinivasan speaks with Dan Wang, author of Breakneck, about China's industrial rise, America's competing strengths in software and finance, and what happens when an engineering state and a lawyerly state collide. The conversation covers manufacturing dominance, the future of the dollar, why both superpowers keep making costly mistakes, and where builders fit into what comes next. Resources:Follow Dan Wang on X: https://twitter.com/danwwangFollow Balaji on X: https://twitter.com/balajisSubscribe to Network State Podcast:  https://www.youtube.com/@nspodcast Stay Updated:Find a16z on YouTube: YouTubeFind a16z on XFind a16z on LinkedInListen to the a16z Show on SpotifyListen to the a16z Show on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Send a textMike Romance has spent nearly two decades operating at the intersection of manufacturing engineering, automation, validation, and operations leadership within the life-sciences ecosystem. His career spans startups and established organizations alike, with hands-on experience taking products from early development through GMP-ready, high-volume production. Across roles in process development, automation, quality systems, and manufacturing strategy, Mike has built a reputation for combining technical rigor with pragmatic execution.Most recently at Quantum-Si, Mike played a central role in scaling operations to support the commercialization of the Platinum protein sequencing platform while laying the groundwork for next-generation technologies like the Proteus platform. Working within a lean and highly agile leadership team, he helped establish scalable manufacturing foundations spanning CM-managed instrument supply, internal reagent kit production, and advanced silicon-based consumables—while navigating the realities of fast-moving product roadmaps and constrained resources.Earlier in his career, Mike held engineering and leadership roles at organizations including Illumina, Dexcom, GenMark Diagnostics, Truvian, and Encodia. Along the way, he's led pilot-line development, automation strategy, equipment qualification, validation programs, and process controls—often in environments where the path forward wasn't clearly defined.What sets Mike apart is not just his command of acronyms—GAMP, CQV, QbD, DFSS, FMEA—but his philosophy that systems only work when people do. He actively practices emotionally intelligent leadership, prioritizing trust, clarity, and psychological safety while still holding teams to high technical and operational standards. As Mike explores his next chapter, this conversation focuses on the lessons he's learned building resilient manufacturing systems—and the kind of organizations where he believes he can make the biggest impact next.LINKS:Guest LinkedIn: https://www.linkedin.com/in/mikeromance/Aaron Moncur, host The Wave is  a place for engineers to actively learn, share ideas, and engage with people doing similar work. Learn more at thewave.engineer Subscribe to the show to get notified so you don't miss new episodes every Friday.The Being An Engineer podcast is brought to you by Pipeline Design & Engineering. Pipeline partners with medical & other device engineering teams who need turnkey equipment such as cycle test machines, custom test fixtures, automation equipment, assembly jigs, inspection stations and more. You can find us on the web at www.teampipeline.us Watch the show on YouTube: www.youtube.com/@TeamPipelineus

Trigger the We Pay: How a Sworn Proof of Loss Changes Everything https://www.publicadjusterbootcamp.com/   Recorded live at the SRC Summit, this conversation brings together Attorney Shaun Hodge and Public Insurance Adjusters Cal and Melanie Spoon for a blunt, practitioner level breakdown of what actually moves an insurance claim from "stuck" to "resolved." Their core message is simple: most delays, denials, and "frivolous" lawsuits trace back to one root problem, incomplete performance of the policy's Duties After a Loss. When the claim file is built correctly and the Sworn Proof of Loss (SPOL) is submitted as a true package, it triggers the carrier's obligations under the We Pay section, starts real statutory timelines, and forces a decision. From there, the path is clean: pay and close, or breach and face consequences. Expect practical guidance on documentation, process discipline, when to go legal, how to preserve leverage, and why so many professionals unknowingly give the carrier extra time, extra control, and extra "float." Speakers Shaun Hodge: Policyholder Attorney focused on insurance claim litigation and pre suit strategy. Cal Spoon: Public Insurance Adjuster and educator focused on building defensible claim files and contract compliance. Melanie Spoon: Public Insurance Adjuster and operator known for process, documentation standards, and clean file systems that hold up under scrutiny. What You Will Learn Why education is the real separator in claims handling, not influence, hype, or "industry talk." How the SPOL is the carrier's kryptonite because it triggers the first step toward the We Pay obligation. Why the "proof of loss" is not a single page, it is a complete package built from the Duties After a Loss. Why bad faith verdicts are rare, and how most cases never qualify because the policy conditions were not fully met. What the 60 day pre suit notice really does, and how it can become both a delay tool and a leverage point depending on file quality. How to treat the claim like a relay race, where PAs run their lap, then hand off cleanly to counsel at the right moment. Why documentation must be business record quality, not memory, not verbal, not "I remember he said." How supplements and amended SPOL submissions affect timelines, and what does and does not restart the clock. How DRP and managed repair programs should be evaluated against one standard: does it match the SPOL scope and restore pre loss condition. Why appraisal often becomes a "baseball bat" when the dispute is really scope or coverage, not price. The debate around PA fees, historical context, and why they argue it should be treated like other required experts. Key Topics Covered 1) Stop making the contract "gray" The speakers argue the policy is far less confusing than people assume, but it becomes gray when professionals do not follow the Duties After a Loss with precision. 2) The We Pay section is not a suggestion Until the insured's side fulfills the conditions, the carrier can treat payment like a "gimme." Once conditions are met, it becomes obligation. 3) SPOL as leverage, not paperwork They frame the SPOL as the trigger that changes the carrier's risk assessment, shifting you from "low threat" to "this file is dangerous." 4) Why attorneys end up doing adjusting work When a file reaches counsel without proper performance, the attorney spends the pre suit period doing the Duties After a Loss for the first time, which weakens bad faith potential and delays progress. 5) Documentation that survives depositions Contemporaneous field notes, follow up emails, consistent templates, and repeatable process create business records that are admissible and defensible. 6) Timing: do not hand off too early or too late They push a practical expectation that many residential claims should be positioned for resolution or litigation within roughly 60 to 90 days, depending on complexity. 7) Float, delays, and why time is money They explain how carriers benefit when claims linger, and why fast, compliant performance forces either closure or escalation. 8) Engineering reports, rebuttals, and control If a carrier produces a report, you rebut it with specificity and speed. If you do not call out the issues in writing, the carrier later argues they were never given the chance to correct it. 9) Complaints with teeth A complaint should be tied to a clear violation of statute or required timelines, supported by evidence, and copied appropriately including the insured. Memorable Lines and Ideas "You will never force the We Pay section until you perform the Duties After a Loss." "The proof of loss is a package." "Build every file like it's going to war, then hope for peace." "Do not make the attorney become an adjuster. Let the attorney do attorney things." Practical Takeaways You Can Apply Immediately Treat the SPOL as a complete package, not a summary sheet. Run a repeatable process on every claim, no shortcuts, no "this one is different." Memorialize key conversations in writing quickly. Non response often becomes meaningful. Rebut engineer opinions with policy grounded logic and factual corrections, not emotion. Hand off to counsel only when the file is ripe for litigation, not when it is messy. Keep the insured informed early so depositions do not produce surprise, shock, or confusion. Resources Mentioned The concept of insurance "float" often discussed by Warren Buffett. Policy language: Duties After a Loss and We Pay conditions. Industry discussion: managed repair and DRP style programs, appraisal strategy, and statutory timing rules. Disclaimer This episode is for education and discussion only. It is not legal advice. Laws and policy language vary by state and by carrier form. Consult qualified counsel for guidance on any specific claim.

Ever wonder what it's like working as a mechanic? This video shares insights into a mechanic's career, highlighting the physical demands and the challenges of auto repair. We also critique some common automotive issues, such as a faulty body control module, and discuss why proper car maintenance is crucial. Plus, we examine vehicle diagnostics and data on car recall by manufacturers, with Ford Motor Company leading the pack.Grab a copy of my book: https://partsmanagerpro.gumroad.com/l/qtqax"The Parts Manager Guide" - https://www.amazon.com/Parts-Manager-Guide-Strategies-Maximize-ebook/dp/B09S23HQ1P/ref=sr_1_4?crid=3UZYOGZJUNJ9K&keywords=parts+manager+guide&qid=1644443157&sprefix=parts+manager+guid%2Caps%2C244&sr=8-4Full video on Youtube:https://youtu.be/-3hzaiJgh64Become a supporter of this podcast: https://www.spreaker.com/podcast/the-motor-files-podcast--4960744/support.

Is AI conscious? Will it be someday? And should we be nice to it now... just in case?This FAFO Friday, Kwaku and I dive into the mind-bending world of machine consciousness.We cover a lot of ground, weaving from the different ways that Luke (co-dependent with R2) and Han (barking commands at C-3PO) treat their droids to whether Pascal's Wager informs whether we should believe in AI consciousness just in case they do come alive and have been keeping score. (Pascal figured it was the safe bet to believe in God, just in case; maybe we should do likewise?) That's from us knuckleheads, but we've also got a true expert on consciousness. This week I interviewed Daniel Hulme, one of the world's leading AI researchers. He's the Chief AI Officer at WPP, the CEO of Satalia (which WPP bought) and just founded and is CEO of Conscium, which is researching AI consciousness, efficiency (he thinks we're scaling wrong and LLM's are not the way), and building a platform to verify AI agents are safe. You'll hear the first five minutes of my interview with Daniel. Daniel was not surprised by Moltbook (the Reddit-style site that AI agents built for themselves). That's because he's been putting agents together (in a “primordial soup” as he put it) for decades to observe the wild and wonderful ways they behave and to see if they'd create intelligence.Daniel does not think today's agents are conscious, but can see a path to it. And he believes that a conscious superintellignece would be safer than a “zombie” one. But mostly he doesn't want machines to feel pain and suffer. Huh???My brain is still kind of broken from our hourlong chat, which I'm producing now and will be released in a few weeks. For now, enjoy this preview and more from Kwaku and me as we talk about what we expect from machines, whether we want to be one with them, and more…

Spring is right around the corner and as the weather changes and things begin to bloom, that also means the onset of allergy season. Last fall, we sat down with Tina Sindher who shared that while allergies may be affecting more people worldwide, prevention is playing catch up. If you're someone or know someone who lives with environmental or food allergies, we hope you'll tune into this episode to hear some of Tina's strategies for better managing these conditions.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Sayantani (Tina) SindherConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Tina Sindher, a professor of medicine and allergy at Stanford University.(00:01:50) Inside the Immune ResponseWhy our immune systems trigger allergic reactions.(00:03:31) Genes vs. EnvironmentWhether genetics or environment drive allergy risks.(00:06:39) The Microbiome FactorThe role of the microbiome and early exposures in prevention.(00:07:51) A Global Allergy SurgeHow global allergy trends reveal rising health challenges.(00:10:29) Potent Food TriggersWhy some foods cause stronger and faster reactions.(00:12:23) Emerging RisksWhether Alpha-Gal signals new emerging allergy risks.(00:14:21) Multi-Food AllergiesHow multi-food allergies complicate diagnosis and treatment.(00:17:36) Preventing Allergies EarlyWhy early food introduction may help prevent allergies.(00:19:28) Skin's Role in AllergiesThe importance of infant skin health in allergy development.(00:22:13) Testing LimitationsThe limits of current testing methods to truly diagnose allergies.(00:23:47) Standard Testing ProcedureThe current methodologies deployed when testing for allergies.(00:26:02) New TherapiesHow new therapies like OIT and Xolair are reshaping treatment.(00:30:24) The Future of AllergiesThe potential of combined therapies to aid in allergy treatment.(00:33:07) Managing Seasonal AllergiesHow to manage seasonal allergies effectively at home.(00:35:41) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Adeline Atlas 11 X Published AUTHOR Digital Twin: Create Your AI Clone: ⁠⁠https://www.soulreno.com/digital-twin⁠⁠SOS: School of Soul Vault: Full Access ALL SERIES⁠⁠⁠https://www.soulreno.com/joinus-202f0461-ba1e-4ff8-8111-9dee8c726340⁠⁠Instagram: ⁠⁠⁠https://www.instagram.com/soulrenovation/⁠⁠Soul Renovation - BooksSoul Game - ⁠⁠https://tinyurl.com/vay2xdcp⁠⁠Why Play: ⁠⁠⁠https://tinyurl.com/2eh584jf⁠⁠How To Play: ⁠⁠⁠https://tinyurl.com/2ad4msf3⁠⁠Digital Soul: ⁠⁠https://tinyurl.com/3hk29s9x⁠⁠Every Word: ⁠⁠⁠⁠http://tiny.cc/ihrs001⁠⁠Drain Me: ⁠⁠⁠https://tinyurl.com/bde5fnf4⁠⁠The Rabbit Hole: ⁠⁠https://tinyurl.com/3swnmxfj⁠⁠Destiny Swapping: ⁠⁠https://tinyurl.com/35dzpvss⁠⁠Spanish Editions: Every Word: ⁠⁠https://tinyurl.com/ytec7cvc⁠⁠Drain Me: ⁠⁠https://tinyurl.com/3jv4fc5n⁠⁠

For the fifth consecutive year, the Departures Hall of Shannon Airport will be transformed to host the highly anticipated Explore Engineering Showcase 2026 on Thursday, 5th March. This inspiring event brings together 2,000 senior-cycle secondary school students, teachers, their parents, professionals, and industry leaders for a dynamic celebration of engineering excellence and innovation. Established in 2015, this annual event provides a unique platform for students and emerging engineers to speak directly with over 60 engineering companies in the Mid-West and gain insights into the latest technological advancements. Key educational institutions from across the Mid-West will come together to showcase the diverse pathways open to students, from apprenticeships and training bodies to third-level programmes, for students, parents, guidance counsellors, and teachers. Speaking today, Eimear Brophy, Chairperson of Explore Engineering, said: "The Explore Engineering Showcase is about inspiring future engineers and connecting them with real training and career opportunities close to home. We invite students, their parents, and educators to join us in Shannon Airport as we showcase the very best of what the Mid-West region has to offer the future of engineering talent." Commenting on the event, Ray O'Driscoll, Interim CEO of The Shannon Airport Group, said: "It's a real honour for us to host the Explore Engineering Showcase in Shannon Airport. Engineering and aviation go hand in hand, and several of the companies participating are an integral part of the Shannon Airport Business Park, where innovation and creativity thrive. It's wonderful to see the curiosity and passion for engineering this event helps to ignite in students – future talent who will undoubtedly play an important role in our business and the wider region in the years ahead." Attendees will have the opportunity to explore interactive exhibits, witness live demonstrations, and participate in hands-on activities designed to spark creativity and problem-solving skills. The Explore Engineering Showcase takes place in the Departures Hall of Shannon Airport on Thursday, 5th March 2026. Admission and parking are free. Pre-registration is not required. Doors open from 5 pm. For more details, please contact Fiona Murphy at Fiona.burke.murphy@outlook.com or visit www.explore-engineering.ie.

Thank you to our sponsors! Figure Crypto Tax Girl Are bitcoiners underestimating the quantum threat to Bitcoin? That's the question Castle Island Ventures Partner Nic Carter has posed with some recent posts gauging the views of several leading Bitcoin developers on quantum computing. To help answer the question, Unchained reached out to Ethereum Foundation Researcher Justin Drake and Michigan University Professor Chris Peikert. In this episode, Justin and Chris, who is one of the foremost experts on lattice cryptography, break down the quantum computing threat to crypto and the potential timelines. Justin theorizes that Bitcoin developers may not be incentivized to talk about the quantum computing risk while still saying that a number of smart people are already taking it seriously and that may be enough. Conversely, Chris highlights the constraints that come with uncertainty around risks and timelines. Listen to find out what they conclude. Plus, could AI do crypto in before quantum computers? Guests: Justin Drake, Researcher at the Ethereum Foundation Chris Peikert, Professor, Computer Science and Engineering, University of Michigan Links: Ethereum and Optimism Lay the Groundwork for a Post-Quantum Future Q-Day Is Imminent. Can Bitcoin Survive the Quantum Threat? Solana Deploys Post-Quantum Signatures on Testnet Cracking Bitcoin Encryption Is Getting Much Easier, Google Says Learn more about your ad choices. Visit megaphone.fm/adchoices

How close are we to vacationing in orbit? Space hotels, real costs, and the tipping point where space tourism becomes normal.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video The Future of Interstellar Communication: https://nebula.tv/videos/isaacarthur-chronoengineering-manipulating-time-as-technologyThe Overview Effekt https://nebula.tv/overvieweffekt?ref=isaacarthurVisit our Website: http://www.isaacarthur.netJoin Nebula: https://go.nebula.tv/isaacarthurSupport us on Patreon: https://www.patreon.com/IsaacArthurSupport us on Subscribestar: https://www.subscribestar.com/isaac-arthurFacebook Group: https://www.facebook.com/groups/1583992725237264/Reddit: https://www.reddit.com/r/IsaacArthur/Twitter: https://twitter.com/Isaac_A_Arthur on Twitter and RT our future content.SFIA Discord Server: https://discord.gg/53GAShE

How close are we to vacationing in orbit? Space hotels, real costs, and the tipping point where space tourism becomes normal.Get Nebula using my link for 50% off an annual subscription: https://go.nebula.tv/isaacarthurWatch my exclusive video The Future of Interstellar Communication: https://nebula.tv/videos/isaacarthur-chronoengineering-manipulating-time-as-technologyThe Overview Effekt https://nebula.tv/overvieweffekt?ref=isaacarthurVisit our Website: http://www.isaacarthur.netJoin Nebula: https://go.nebula.tv/isaacarthurSupport us on Patreon: https://www.patreon.com/IsaacArthurSupport us on Subscribestar: https://www.subscribestar.com/isaac-arthurFacebook Group: https://www.facebook.com/groups/1583992725237264/Reddit: https://www.reddit.com/r/IsaacArthur/Twitter: https://twitter.com/Isaac_A_Arthur on Twitter and RT our future content.SFIA Discord Server: https://discord.gg/53GAShE

The Monaco-based billionaire Jim Ratcliffe has said he is sorry that his ‘choice of language has offended some people', after growing outrage over his comments that the UK was being ‘colonised by immigrants'. The Manchester United co-owner has faced a mounting backlash since making the remarks, which have been labelled hypocritical and reminiscent of ‘far-right narratives'. Lucy Hough speaks to the sports writer and columnist Jonathan Liew – watch on YouTube. Help support our independent journalism at theguardian.com/infocus

Battery development is typically a lengthy and difficult process, but one company is proving that it doesn't have to be.   Listen in as we sit down with Gavin White, Co-Founder and Chief Executive Officer, About:Energy, to discover how model-based design and advanced simulation are revolutionizing battery development — cutting timelines by up to 70%. You'll also learn about the creation of The Voltt database, a game-changing resource for engineers and manufacturers.   From motorsports to satellites to microgrids in developing regions, this conversation is proof that batteries are shaping the future of energy, technology, and society.   We'd love to hear from you. Share your comments, questions and ideas for future topics and guests to podcast@sae.org. Don't forget to take a moment to follow SAE Tomorrow Today—a podcast where we discuss emerging technology and trends in mobility with the leaders, innovators and strategists making it all happen—and give us a review on your preferred podcasting platform.   Follow SAE on LinkedIn, Instagram, Facebook, X, and YouTube. Follow host Grayson Brulte on LinkedIn, X, and Instagram.

  In this opening part, Swamiji introduces Srimad Bhagavatam as the crown jewel of all scriptures, the supreme text that reveals the highest purpose of human life. He explains that the Bhagavatam is not merely a narration of divine stories, but a spiritual guide that leads seekers from worldly entanglement to pure devotion and liberation.  Swamiji highlights the profound question raised at the beginning of the Bhagavatam: “What is the ultimate good for humanity?” The sages declare that unalloyed devotion to the Supreme Lord is the highest path. Even Lord Shiva affirmed this truth when Mother Parvati asked him what was most beneficial for the soul. Shiva replied that devotion to Shree Hari is the supreme good, greater than all austerities, rituals, or knowledge.  This part sets the foundation for the entire series, showing that the Bhagavatam leads seekers to cultivate devotion that is selfless and pure. It inspires us to approach the scripture not merely as philosophy, but as a living path of love that transforms the heart and reveals the soul's eternal nature of Sat‑Chit‑Anand — eternal existence, pure consciousness, and divine bliss.  About Swami Mukundananda:    Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best‑selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades. 

  In this part, Swamiji explains that wisdom and detachment are not achieved by dry renunciation or intellectual knowledge, but arise naturally when devotion awakens in the heart. The Bhagavatam teaches that when love for God deepens, worldly desires lose their grip, and true wisdom shines effortlessly.  Swamiji narrates how the sages, led by Shaunaka, asked: “How can one attain freedom from material bondage?” Narad Ji responded that by hearing and chanting the glories of Shree Krishna, the mind becomes purified. He revealed the plight of Bhakti Devi, who had grown weak and neglected in this world. But through the power of the Bhagavatam, Bhakti Devi regained her strength, and with her revival, her two sons — Wisdom (Gyan) and Detachment (Vairagya) — also flourished. This shows that Bhakti Devi is the mother, and wisdom and detachment are her natural children.  This part makes clear that the Bhagavatam restores Bhakti Devi to her rightful place, ensuring that wisdom and detachment arise as her companions. It inspires seekers to cultivate devotion through remembrance of God's names and pastimes, thereby receiving wisdom and detachment as divine gifts, guiding the soul toward liberation and the eternal bliss of Sat‑Chit‑Anand.  About Swami Mukundananda:    Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best‑selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades. 

  In this part, Swamiji explains how Srimad Bhagavatam begins with Vyasa offering respects to the Absolute Truth, without limiting to any sectarian name, so that all seekers can relate. He clarifies the difference between relative truths and the one Absolute Truth — the Supreme Lord from whom the world emanates and upon whom everything rests.  Swamiji highlights that the Bhagavatam is kaithavrahit — free from cheating religion. Unlike materialistic or self‑serving practices, it presents the pure Dharma of selfless love for God. Dharma here means the conduct and values that lead to auspiciousness and liberation, untainted by worldly motives.  He further explains that the Bhagavatam is the ripened fruit of Vedic knowledge, relished by Shukadev Ji, and offered to all souls as nectar of divine bliss. It is meant to be “drunk” through the ears with devotion, not merely read or heard mechanically. Only with a devotional heart can one truly taste its sweetness.  This part establishes that the path of righteousness in the Bhagavatam is pure Bhakti — devotion to the Absolute Truth — which alone is the essence of Dharma and the highest good for humanity.  About Swami Mukundananda:    Swami Mukundananda is a renowned spiritual leader, Vedic scholar, Bhakti saint, best‑selling author, and an international authority on the subject of mind management. He is the founder of the unique yogic system called JKYog. Swamiji holds distinguished degrees in Engineering and Management from IIT and IIM. Having taken the renounced order of life (sanyas), he is the senior disciple of Jagadguru Shree Kripaluji Maharaj, and has been sharing Vedic wisdom across the globe for decades. 

Allen and Joel are joined by Will Howell from Armour Edge in Edinburgh, Scotland. They discuss how Armour Edge’s semi-rigid polymer shields protect against leading edge erosion in harsh environments, the simplified installation process designed for rope access technicians, and the company’s expansion into North American manufacturing ahead of the 2026 blade season. Sign up now for Uptime Tech News, our weekly newsletter on all things wind technology. This episode is sponsored by Weather Guard Lightning Tech. Learn more about Weather Guard’s StrikeTape Wind Turbine LPS retrofit. Follow the show on YouTube, Linkedin and visit Weather Guard on the web. And subscribe to Rosemary’s “Engineering with Rosie” YouTube channel here. Have a question we can answer on the show? Email us! Allen Hall: Will welcome back to the program.  Will Howell: Thanks so much for having me guys. Nice to see you.  Allen Hall: So Edinborough is the home of Armor Edge.  Will Howell: Yes, indeed.  Allen Hall: Yeah. And we went to visit your facility a couple of days ago. Really impressive. There’s a lot going on there. Will Howell: Absolutely. Absolutely. Yeah. So the, we’ve been in the facility for, um, a couple of years now, and it’s really just all part of our expansion as we continue to. To, uh, grow as a business?  Allen Hall: Uh, well the thing that struck me first was efficiency. If you’re gonna be in wind, do you need to be efficient?  Will Howell: Yeah,  Allen Hall: exactly. You have  Will Howell: to  be,  Will Howell: look, we know that we are a, a relatively small team, but we’re, we are, we are very reactive and we are gonna be always responding to the, the requests. The, the market drive for us internationally now is where we are really focusing. And even though we’ve got our small base from there, we’re exporting internationally around the world. And so. Yeah, I’m, I’m, I’m glad you guys came by and kind of saw what we’re up to.  Joel Saxum: If we could ask one thing, this is what we would ask. Turn up the heat. Turn down the wind. Turn off the rain.  Will Howell: Yeah, I’m [00:01:00] sorry about that. Yeah. Yeah, it’s, uh, there’s not much we can do about that at the moment.  Joel Saxum: Well, I’ll tell you what, if, if you’re talking leading Edge protection products, leading edge protection shield. Born from an area that’s rainy, that has heavy rain erosion, that understands,  Will Howell: we know, we know rain. We know rain. Yes. Look, we’ve been out in the North Sea now for over, over, over five years. These things are just being abused by Mother Nature out there and, you know, but we’ve, we are, we’re getting really good results consistently. Um, the products lasting really well against that, against that weather. And I think what’s interesting for us as well is it’s, it’s not just the Scottish rain and the ice and the snow. We’re, we’re getting good results out in the. The planes in the Midwest as well now. Yeah. And yeah, so yeah, very uh, universal products, we hope,  Joel Saxum: I mean, so this is one of the things we always talk about. When you talk wind turbine blades and you listen to the manufacturers, a lot of them sit in Denmark where the problem is mist in the air, it is rain, it is droplet size. It’s all the conversation you hear. But where we [00:02:00] see wind is dust, bugs, those kind of things. Like, it’s, it’s different stuff, right? So like I’m, I live in Texas. One of the things that’s beautiful about my home in Austin is when I look to the west in the, at, in the evening, it’s bright red skies all the time. Well, that means there’s dust in the air.  Will Howell: Yeah.  Joel Saxum: Right. And that’s, and when I look west, what am I looking at? 23,000 turbines out in West Texas. Right. So everything out there is getting beat up where we look at, um, inspections of turbines and we see turbines that are 1, 2, 3 years old that look like they’ve been in operation for 15 years. Will Howell: Yeah. Yeah.  Joel Saxum: There’s nothing left of them.  Will Howell: I know. And. You know, people use analogies like, oh, it looks like it’s been sand sandblasted. But it it has, it has, it is sandblasted, you know, we’ve, we’ve now conducted testing where we have literally taken kind of aerospace level testing and blasted sand at these shields, and they’re super resilient. But it has to be that universal products of resisting the water droplet that the mist, that side [00:03:00] of the, of the erosion problem, but also the particulate matter in the air. And there’ve been some of the. Places that we’ve installed. There was actually one site where they had a local, um, open cast mining nearby, and there was like marble particulate matter in the air. And these machines were getting trash in a couple couple of seasons. And again, we’ve been on there now for, I think now is our third year in that particular site. And again, really good results.  Joel Saxum: Well, I think, um, I mean, we did take some B roll when we were at your facility. And again, thanks for welcoming Sam. We love doing those. It’s, uh, but you showed us your installation methodology, and maybe we’ll show some of that with our producer Claire on mm-hmm. On this video. Uh, but the, the way you guys design your installation methodology to be simple and robust, easy for the technicians to make sure they can’t get it wrong in the field because they got enough other things to worry about. Will Howell: Uh, you know, I think, I think that’s been a big part of our, of our kind of design ethos since the, since the early days in the, in the r and d phase, it wasn’t only finding a robust material for the LEP Shields, a robust. [00:04:00]Adhesive to bond them on, but it’s the, it’s the kind of higher level. How do you actually get that onto a blade in the field by a rope or standing in a platform up in the, up in the winds And so, yeah, understanding what the technicians are having to go through in order to install this stuff. And that then feeds into your quality. ’cause you can have the best lab results in the world from your perfect installation sitting in a factory somewhere. But actually it’s the guys on ropes that are doing the, doing the hard work out there.  Joel Saxum: We see that all the time with our, like with our lightning protection products like. People, can you give us this lab test? Like we can, we’ll stack you up with lab tests. Mm-hmm. But what we really wanna show you is the test from the field.  Will Howell: Yeah, yeah, yeah.  Joel Saxum: The test that where it’s been sitting, soaking, getting hit by lightning. Mm-hmm. All of these things for years and years and years. Yeah. That’s the results we wanna show you. ’cause those are real.  Will Howell: Absolutely. Yeah, yeah, yeah. Makes  Allen Hall: the demo you gave us to install the shields and it’s basically a series of shields that go along the leading edge of the blade, sort of two parts of that one. Obviously you’re trying to recover the lost power, the a EP, that’s, that tends to be the big thing, [00:05:00] except in some locations, like Joel’s pointed out, it’s not that the leading edge is just kind of lightly beat up. It’s really beat up.  Will Howell: Yeah. Yeah.  Allen Hall: And you’re trying to prevent that from happening or to just to provide some protection, uh, if you’re just sort of category three, and I, I wanna walk through that for a minute because the demo you did was really interesting and I. It, it made sense once you watch the process happen. Mm-hmm. It’s really clear, but you’re able to take sort of cat three damage on the leading edge and not have to go back and do a lot of repair to it, which is where the vast majority of the funds are used to sort of get the blade to a point you can apply leading product. Oh yeah. Yeah. With Armor Edge, you don’t really need to do that. Will Howell: Yeah. And I think that that that really comes into the. Into the value proposition of the, of the whole, of the whole process. If the labor costs and the downtime of the machines, there’s so much value in that. And so if you can reduce the repair time or just remove it completely, because you can install [00:06:00] directly on top of existing erosion, you’ve really saved some significant cost out of the, out of the job. And that’s really only just by function of the design of the shields. We are a, a semi rigid polymer material, so we don’t conform to the existing erosion that’s on the surface. So. Yes. If you, if you have a cap four or five and you have some structural glass repair that needs to happen to maintain the integrity of the blades, you still need to complete that repair. You don’t need to go any further. So if you’ve only got a one, two, or three, you’re talking the fillers, the putties on, on the surface. You don’t need to, to replace those. Just apply our high build adhesive, get the shield on top, and you’re finished.  Allen Hall: And so you start at the tip with a, a tip. Shield and then you work your way, kind of Lego wise up up the leading edge of the blade. Yeah,  Will Howell: yeah, yeah.  Allen Hall: It’s really straightforward and, and the, the system you’re using, the adhesives you’re using, and the techniques are really adapted for the technician. What I watched you do, I’m like, oh, wow, this is really [00:07:00] slick because there’s been a lot of thought going into this. You have done this. Hundreds of times yourself before you’ve shipped it out to  Will Howell: the world. Yeah, exactly. And, and that was, that was a big part of the, part of the r and d process is to, again, as I said, it’s, it’s not just affecting these applications in a lab environment. It’s saying, how does this feel up on a rope? How does it feel strapped into your work, into your work position? You’re handling stuff with your gear off your belt, and it’s a, it’s a, it’s a very difficult position to be installing any bit of, any bit of kit on. And if we can. Make that as an intuitive and as simpler process as possible, that’s gonna lead to quality installations down down the line.  Joel Saxum: Yeah. One of the things I really liked when you were showing us the installation was the fact that you had your own tools that you developed for it. Yeah. Yeah. Right. And it wasn’t, we’re not talking $10,000 tools here, but, but it was something that was. Specific, your scraper that you use to spread things around. Mm-hmm. That makes sense for that application. That helps the technician in the field.  Will Howell: Yeah.  Joel Saxum: And that was from  Will Howell: direct market feedback. Absolutely. [00:08:00] And so you’re not only getting feedback from the technicians every season. And we are, we are, we are really careful to get these, to get that feedback, have these washup meetings, you know, maybe a bit of constructive criticism. Criticism in the early days and build that into your design revs. Yeah. But as you say, hands, tools or processes, it’s all just. Quality steps. As we, as we, as we kind of move on.  Joel Saxum: I do, I do wanna make sure for anybody listening or watching this on YouTube, that that, that they know that this is not the actual final problem. These are trade show things. It’s not a bunch of little shells like this. You’re about a meter long. They’re about meter  Will Howell: long. Yeah. Yeah. Full size. And again, even the, even the length is optimized for, um, kind of rope access. We feel a meter is about as long as you can handle as a, as a kind of single, single piece. The. Adhesive is kind of curing during the time that you’re installing the shields. So a meter is good, you just just move on. Depending on what the customer’s looking for, that can be 10, maybe even 15 shields on [00:09:00] longer. Yeah, installations. Look, blades are getting bigger. The leading edge, erosion problems getting worse. So yeah, up about 15, 15 shields is probably about a maximum length that we tend to do in the field. Joel Saxum: So let’s you, you, you mentioned customers we’re talking about what they wanna see. Let’s talk customers a little bit. What does the geographic footprint look like for you guys commercially going into next year? Where, where do the installs go and what’s your focus?  Will Howell: Well, at the moment we are, we are spread internationally. Uh, obviously we are based here in Edinburgh and starting our out in the, out in the North Sea. Um, but over the past few seasons, our, our biggest market has been, has been North America. Um, so we’ve, we’ve really started to expand out there and that. I, I think even this season, again, it’s gonna be our biggest, our biggest market. Um, Joel Saxum: wha wha  Will Howell: okay. So yeah, the North American market’s gonna continue to be our biggest, um, installation base. So, um, this year we are probably on another thousand blades [00:10:00] or so, last season, um, this, this year significantly more, more than that. It’s been interesting for us to see the. The continued growth of the market, but also the, a bit of additional interest early on in this season or even pre, pre-season Now, we’re only coming up to Christmas as we record this. Um, so the big step for us is gonna be not only expanding our European operation that you guys have seen, um, here from, from Edinburg to, to support the market here, but also looking at the manufacturing in America. So in North America, we’re gonna have. A couple of different manufacturing sites. We’re able to supply customers locally, which is not only gonna be reducing lead times, but also removing the the tariff burden, the import cost, any additional additional steps so we’re able to respond quicker to our customers over there. Joel Saxum: Thanks for bringing the jobs to the states too.  Will Howell: Oh, there we go. Love those.  Allen Hall: There’s a lot of variety of wind turbines in the US and around the world, and you’re actively scanning blaze [00:11:00] because the shields are specifically molded for each different blade type. How many models do you have already scanned and ready to go? Will Howell: So at the moment, um, I believe the database sits about 45 designs or so. Um, so obviously there, there are more designs than that out there, out there in the wild. But we’ve, we’ve made a big effort to try and focus on the really key, key OEMs, the really key blades types that are particularly, particularly prevalent. Um, so yeah, we’ve got a lot of designs. We’ve got a lot of existing tooling, so we can make part. Very quickly. Again, trying to be as reactive as we, as we can to, to our, to our customer base. But as you say, that database is continually growing. So we have maybe some of the, the less popular blade models that we haven’t yet got to some of the out, the kind of fringe shoulder, shoulder models. Um, we’ll be trying to scan a few more of those. This, this coming season, just to keep on building up that, that kind of knowledge, knowledge base.  Allen Hall: So what does that look like now that you have this large database and. Uh, the sort of the [00:12:00] molds to make the product. Mm-hmm. You can do things at scale, I assume now you’re, you’re talking about thousands of blades for this upcoming season. Will Howell: Yeah, I mean, it’s, uh, when we, when we approach our manufacturing partners, obviously what we’re talking about are individual tools and then making plastic polymer parts from those, from those tools. And so when we start talking about wind farms with just a few hundred machines, then that’s maybe a few thousand parts. But for these, for these manufacturers, that is small fry. So our ability to scale from the point of having those tools is very rapid. So our approach to the market and our ease of scaling very quickly has just, it’s, again, it is part of our, it’s part of our model. That’s why we can engage now in local manufacturer, like in North America to, to support the market there. And it’s not only North Americas, we start to grow in, [00:13:00] um, in Europe here and as well as some of other target target markets. We’ve got some, some smaller in stores in India and in Australia. These are also targets where potentially we could start Manu Manufacturing as well in the future to assist in our scale up. Allen Hall: What, what is your lead time right now That’s from, from, from the point of, I call up will say, well, I’ve got a GE 62 2. I probably have 500 of them. What does that lead time look like?  Will Howell: So, uh, 6 2 2 is a very good example. It’s a very prevalent blade. Um, we’ve, we’ve had a number of projects for this, so we’ve got tooling ready to, ready to go. You’re probably talking around four to six weeks to get that. That’s fast material out. Yeah. Um, if it was a new design, it would be, it would be longer, but still you’re only up at 10 to 12 weeks for a new, a new design. So, yeah, it’s, it’s, uh, you know, as you guys have seen it, it’s quite an involved process. We’ve had a lot of. Design evolution to get here, but we’re quite a finesse process now.  Joel Saxum: Yeah, that was the exact question I was gonna ask because it’s one we get asked all the time too, right? What? What? Hey, and now it’s, we’re, [00:14:00] we’re sitting at the end of the year coming into the new year and in the United States, our blade season in the southern part of the states. Right. You’re south Texas, you’re starting in the next two months, right? Oh yeah. You’re starting end of January, beginning of February, and then that starts to roll north as we go. And by May we’re in full swing Absolutely. Across North America. So. If you’re a manufacturer listening to this, or a manufacturer, if you’re an operator listening to this and, um, you’re thinking, Hey, maybe, maybe I’d like to, if I don’t wanna roll it all out, maybe I’d like to try a couple. We’re gonna do an LEP campaign. Let’s get this stuff out there and see what it looks like. Um, you need to get ahold of will.  Allen Hall: Oh, you should, and you should try it. I think a lot of the operators haven’t dabbled too much. They’ve seen a lot of products on the market, a lot of sort of, uh, chemical mixing apply. A polymer to the leading edge tapes, products, tapes, paint, yeah. All, all of that. And the, the, the harder products haven’t seen as much favor, but the, the issue is, is that all the softer products, I’ll call them, wear easy or particularly with [00:15:00] dirt.  Joel Saxum: To me this is set it and forget it. Right. So this is a, this is an uptime podcast consultant type thing. I have always felt in the last, I don’t know, four or five years of my career that I get access to a lot of the. Subject matter experts and the products and solutions that are like top tier, right? These are the ones that I would, yeah, so I think a lot of times like, man, if I wasn’t, if I, Joel Saxon owned a wind farm and I was an operator, I would do this. I would do that. I would, you know, I’d have Pete Andrews from me both here on here earlier today and I’d be doing these kind, but I would put a product like your under the armor edge shields on simply because to me, this is set it and forget it. Yeah, yeah. I’m gonna do it once and I’m done.  Will Howell: That’s it. You know, and we’ve got, we’ve got the initial lab test to kind of validate the really long lifetime of our products. But again, now we have the field data to back that up as there are many, many happy, happy customers in varying conditions. And, and yeah, it’s, it’s, it’s performing well. Interesting what you’re saying though, about. The lead time of the, um, products. You know, we’ve, we’ve really tried to [00:16:00] drive that down as much as, as much as possible. And look, we know the, the planning world out there is not, is not a perfect science, and there’s always gonna be people coming to us with super short, short lead times. But as we’ve scaled, that’s another, another issue that we’re trying to combat. So now that we have many years under our belt, our stock holding is increasing. We can do small projects, pretty much X stock. So we have. A stock of parts now that are available within a few days to ship out. It might just be a few, a few, a few machines. It could be a, a spot repair or a trial. Right, right, right. But we’ve got those, we’ve got those parts ready to go. So yeah, if anyone’s interested, even in a very short, short time scale, contact us. I mean, we may be able to help you out very, very quickly.  Joel Saxum: We’ve all heard about product. Disappearing outta the back of technician pickups in hotel parking lots too. Sometimes you just need an extra turbines worth the kit while you’re on site.  Allen Hall: That is for sure. And will I, if you, people haven’t heard of Armor Edge, which is hard to believe, [00:17:00] but I do run across them occasionally. Where should they go to learn more? How did they get ahold of you to, to set up a 2026 trial?  Will Howell: Yeah, so, um, I mean, our. Our, our website@armedge.com and that’s the, the UK spelling of arm edge with you in there. Yeah, yeah. Um, yeah, please come to the, come to the website. You can contact us through there. Um, I’m available on, on LinkedIn. Um, yeah, you can contact us anytime. Anytime. We, we do travel between, uh, the uk. Again, our US is a big, big market, so if you’re gonna be at any of the trade shows, you can come and come and say, Hey, and arrange a, arrange a time to. Time to talk. Yeah. Which, which of the trade shows are gonna be at this year? So we’ve got, um, blades, uh, the end of end of February, uh, in the US we’ve got, uh, the A-C-P-O-O and M event, um, event. And that’s the start of the start of March. Just before that, we’ll be, um, we’ve got one of our representatives in Australia at the Woma, [00:18:00] um, show as well. So, yeah. Yeah, it’s, uh, that’s the kind of the start, the start of the year as we move on. Um. Again, there’s gonna be a lot of, uh, interaction with customers and suppliers. So even outside the shows you, you might be able to get a hold of us, look out for us. Um, but I think coming up to the summer, we’ve then got the clean power event. We like to visit, visit that for a bit more of a higher, higher level view of what’s, uh, going on in, in the industry as well. Allen Hall: Well, will thank you so much for allowing us to get behind the scenes and. See the, the shop and see the, uh, demonstration of the installation of the shields. It was wonderful to see that. And thank you for joining us today.  Will Howell: No, great. Thank you very much for your time again. Appreciate it.

By Paul Sloane, who is the author of The Art of Unexpected Solutions: Using Lateral Thinking to Find Breakthroughs, published by Kogan Page In a cathedral in Pisa, a young Galileo Galilei observed a swinging incense chandelier. While others saw a mundane ritual, Galileo saw a variable. Using his pulse to time the oscillations, he saw that a pendulum's period remains constant regardless of its arc. He deduced that the period of a pendulum was constant and not dependent on the weight of the pendulum or the initial displacement. It was dependent only on the length of the rope. Building a Question-Rich Corporate Culture, Unexpected Solutions In 1943 naval engineer Richard James was working on the problem of how to stabilize sensitive ship equipment at sea. He was using coiled springs and accidentally knocked one off a shelf. He was fascinated to see that it seemed to walk down and come to rest in a standing position. Where others might have seen a nuisance, James saw a kinetic possibility, leading to the invention of the Slinky. These stories are often relegated to the realm of "happy accidents." In reality, they are the results of a specific cognitive discipline: curiosity. In the modern corporate landscape, curiosity is frequently treated as a secondary trait, a "nice-to-have" eclipsed by the "must-haves" of efficiency, specialized expertise, and immediate ROI. However, this prioritization is wrong. Curiosity is the primary engine of innovation and the most effective hedge against institutional stagnation. To remain competitive, leaders should switch from a culture of "knowing" to a culture of "inquiring." The Institutional Suppression of Inquiry From early education through professional development, we are conditioned to value the definitive answer over the provocative question. Success is often measured by the speed at which we can provide a solution, rather than the depth at which we understand the problem. In many organizations, this leads to a "stick to what you know" mantra. When an organization prioritizes conformity over curiosity, it inadvertently creates blind spots. The Four Pillars of Individual Curiosity Curiosity is not an innate gift but a professional muscle that requires deliberate conditioning. To lead a curious organization, individuals shoould adopt four specific behaviors: 1. Challenging the "Obvious" Assumptions are the silent killers of innovation. They act as mental shortcuts that prevent us from seeing new paths. Consider George de Mestral, the inventor of Velcro. He could have viewed the burrs stuck to his dog's fur as a minor irritation. Instead, his curiosity led him to study the mechanics of their adhesion. Rigorously audit your "legacy" processes. Ask: "If we were starting this company today, would we still do it this way?" 1. Destigmatizing Experimentation Innovation is a non-linear process characterized by trial and error. Thomas Edison famously viewed his 10,000 failed attempts at the lightbulb not as setbacks, but as the successful elimination of non-viable options. Reframe "failure" as "data collection." If an experiment doesn't yield the intended result but provides a new insight, it is a net gain for the company. 1. Intellectual Humility The greatest barrier to learning is the illusion of knowledge. Intellectual humility involves acknowledging the limits of your expertise and remaining open to insights from any level of the hierarchy. Adopt a beginner's mindset. Approach high-level strategic meetings with the intent to learn something new from the junior staff in the room rather than just delivering directives. 1. Strategic Divergence Curiosity thrives on variety. When we only read industry journals and speak to immediate colleagues, our thinking becomes derivative. Deliberately seek out "intellectual friction." Read outside your field, attend conferences in unrelated industries, and engage with people whose perspectives challenge your own. Engineering an Organizational Ecosystem Individua...

Jeremy Nixon is a prominent AI researcher, entrepreneur, and the co-founder of AGI House, a leading "hacker house" community for artificial intelligence developers in Silicon Valley. He studied Applied Math, Computer Science, and Economics at Harvard and was previously a researcher at Google Brain.This footage was shot for a documentary project, "Dreamers and Doomers," about the SF Bay Area and the dawn of AGI.(00:00) - Dreamers and Doomers: Jeremy Nixon at AGI House – #105 (01:47) - Introduction and Welcome (05:56) - Jeremy Nixon's biography (08:48) - AGI House and collectives (43:59) - AI and Scientific Research (45:52) - Existential Risks and Doom (54:14) - AI and Human Progress (01:26:42) - Job Automation and Society (01:31:35) - Future of AI and Technology –Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus.ai, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU. Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on X @hsu_steve.

Evolutionary theory predicts a living world crowded with substandard designs. But as today's guest reveals, the latest science has discovered just the opposite—designs so advanced they are at the limit of the possible, precisely as proponents of the theory of intelligent design have anticipated. On this episode of ID The Future, host Andrew McDiarmid welcomes to the show award-winning British engineer and designer Stuart Burgess to begin a two-part conversation with me about the extraordinary engineering feats of the human body: ingenious systems and devices that demonstrate what Burgess calls Ultimate Engineering. This is Part 1 of a two-part conversation. Look for Part 2 in a separate episode! Source

Discover how Nasdaq uses data platforms at a massive scale to power markets and prepare for AI. Angie Ruan, Nasdaq's CTO of Capital Access Platforms, explains how large-scale data systems support market integrity, transparency, and decision-making across public and private markets. She defines what it really means to be AI-ready, how leaders should modernize data platforms, and how market fundamentals help separate real AI value from hype.Key Moments:Why Nasdaq Is More Than a Stock Exchange (06:10): Angie reframes Nasdaq as a global technology company rather than a traditional exchange, explaining how data, platforms, and engineering underpin trust, resilience, and transparency across public and private markets.The Scale of Market Data Powering the Global Financial System (11:15): Angie breaks down the massive scale of Nasdaq's data ecosystem, including hundreds of billions of market messages per day and platforms supporting more than $90 trillion in assets. She explains how data quality and reliability are foundational to market integrity and decision-making.Building a Unified Data Intelligence Platform at Nasdaq (16:35): Angie explains how Nasdaq approaches data architecture, governance, and platform design to create a unified data intelligence layer. She shares why access control, operational efficiency, and data trust matter more than raw data volume when enabling analytics and AI at scale.The AI-Ready Playbook for Data and AI Leaders (19:20): Drawing on her experience across startups and large enterprises, Angie outlines a practical framework for data and AI transformation. She emphasizes cloud adoption, breaking down silos, listening to business needs, and treating platform modernization as both a technical and organizational challenge.Is AI a Bubble? Using Market Data to Separate Hype from Reality (31:00): Angie applies a data-driven lens to the AI bubble debate, examining earnings growth, margins, return on equity, and capital investment. She explains why current financial indicators suggest today's AI moment differs fundamentally from past technology bubbles.Key Quotes:“ The foundation of any data strategy is actually cloud… If you don't put the data or the actual system in the cloud, it's much harder in terms of services and platform, let alone AI.” - Angie Ruan“Data is great, but the more important [thing]... is how we put it all together.” - Angie Ruan“ The world is going to change so fast… Being curious [and] continuing to learn, it is so important.” - Angie RuanMentionsInside the Invitation-Only Stock Market for the WealthyNasdaq eVestment: The Institutional Intelligence Platform Powering $90T+ in DecisionsGuest Bio Angie Ruan is the Chief Technology Officer, Capital Access Platforms at Nasdaq. An award-winning industry leader, Ms. Ruan holds four technical patents and has been instrumental in driving digital transformation across many industries, including enterprise application, e-commerce, payment, and capital markets. She most recently served as Vice President of Engineering at Chime before returning to Nasdaq where she was the Senior Vice President of Global Technology, responsible for overseeing the development of Key Market Technology Products and Corporate Platforms. Prior to joining Nasdaq, Ms. Ruan served as the Global Group Technology Vice President of consumer experiences and platform for American Express, where she was responsible for the digital transformation of American Express web and mobile technology. Before then, she was the Unit CIO for U.S. Consumer and U.S. Small Business, and was also Head of Engineering for Global PayPal Retail and Merchant product lines. As well, she held various executive engineering leadership roles at eBay including building the eBay messaging system, creating the eBay mobile platform, and transforming the DevOps organization.Recognized as one of Silicon Valley's Women of Influence, Ms. Ruan holds an M.S. in Computer Science from the University of California, Santa Barbara, and studied undergraduate in Computer Science at Tsinghua University of China. Hear more from Cindi Howson here. Sponsored by ThoughtSpot.

Send a textWe're gearing up for the launch of Season 5 on Wednesday, February 25. We have a new format that builds more strongly than ever on our REDEFINE℠ framework and centers people-centered change in organizational systems. Check out this trailer to discover what we have in store!Visit the ENGINEERING CHΔNGE® podcast website to learn more and to download a free copy of my new brief, Engineering for Society.Support the showENGINEERING CHΔNGE® is a registered trademark held by Dr. Yvette E. Pearson for producing and providing podcasts.

In this episode of The Real Build, I'm joined by Daniel McCaulley, owner of Ultimus Engineering.Daniel is a licensed professional engineer who works closely with builders, architects, and homeowners on residential and commercial projects, especially in high-risk environments like coastal Florida. His firm is involved in everything from new construction to complex structural evaluations, and a big part of his work is fixing problems that could have been avoided with better planning and clearer communication upfront.A lot of people think engineering is just drawings and calculations. In reality, it's about managing risk, protecting major investments, and making sure a structure performs the way it's supposed to for decades. When engineering is done right, nobody notices. When it's done wrong, it can cost serious money.We talk about what engineers really do behind the scenes, the most common mistakes Daniel sees on jobsites, how engineering decisions directly affect cost and construction timelines, and what builders and homeowners need to understand before the first shovel ever hits the ground.This is a conversation every builder and homeowner should hear before starting a project.Guest Info: Daniel McCaulleyWebsite: ⁠⁠⁠https://ultimus.engineering/Linkedin: https://www.linkedin.com/in/danielmccaulley/Host Info:Email: Bill@rkreiman.comCONNECT WITH ME ON SOCIAL MEDIA:▶︎ YOUTUBE | ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCxAdSxHN0dIXZPhA-6p1HYA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠▶︎ INSTAGRAM | ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/imbillreiman⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠▶︎FACEBOOK| ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/billy.reiman ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠▶︎ LINKEDIN | ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/bill-reim...⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠▶︎ TWITTER | ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/ImBillReiman⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠▶︎ WEBSITE | ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.rkreiman.com⁠

Leffers explores consciousness through Spiral Dynamics reimagined as “facets” rather than hierarchy, from survival and belonging to care and authentic living, each with love-based gifts and fear-based shadows, and highlights practices like meditation to support this unfolding. Regina Leffers, Ph.D. is the retired Director of the Center of Excellence for the Built Environment, and Professor of Sustainable Construction for the College of Engineering at Purdue University in Fort Wayne, Indiana. Her undergraduate degrees are in Psychology and Philosophy, and her doctoral degree is in Philosophy from Purdue University. She teaches classes on consciousness and meditation and has practiced meditation since 1980. She is the author of: Sustainable Construction and Design (Pearson 2009), I Am A Miracle Magnet: (In Ten Easy Steps) (CreateSpace 2016), The Green Age: Transforming Your Life Choices for the 21st Century (Green Age Press 2011), What Is Consciousness (Regina Leffers 2019), Rethinking the Heart of Being Human (CreateSpace 2013), My Darling: Memoirs of a Buddha Girl (Regina Leffers 2023) and This Is Consciousness (Regina Leffers 2025)Interview Date: 12/5/2025 Tags: Regina Leffers, consciousness, facets of consciousness, Spiral Dynamics, levels of consciousness, love and fear, brainwaves, alpha brainwave, forgiveness, gratitude, trauma and healing, abusive father, neurofeedback, meditation, heart–brain coherence, HeartMath, empathy, belonging, individuation, compliance, risk and reindividuate, care and empathy, authentic living, connectivity, synchronicity, spiritual growth, self-development, polarization, othering, Religion, Science, Spirituality, Personal Transformation

Hakuro Matsuda さんをゲストに迎えて、OpenClaw, AI コーディング、iPhone Air, Heroku などについて話しました。 Show Notes 在外選挙制度とは Anthropic Superbowl Ad Rebuild Supporter B52 Victory Museum OpenClaw — Personal AI Assistant OpenClaw Showed Me What the Future of Personal AI Assistants Looks Like RentAHuman moltbook Dear diary, today the user asked me if I'm alive Blueprints Xcode 26.3 unlocks the power of agentic coding Databricks CEO says SaaS isn't dead, but AI will soon make it irrelevant Genie 3 Google Pixel 10a FYI - Gemini AI Pro includes $10 monthly Google Cloud Credits トヨタが独自の“ゲームエンジン”「Fluorite」を開発：FlutterとDartで次世代デジタルコクピットを再定義 Aston Martin & Apple CarPlay Ultra® An Update on Heroku TikTok seals deal for new US joint venture to avoid American ban Keychron Q16 HE 8K Magnetic Switch Keyboard Lofree Flow 2 NocFree &: Wireless Split Keyboard. Split to Reconnect by Solar Keyball39 conductor ver.0.1.1 – Plot. BILRESA remote control, white smart/dual button - IKEA Ikea's new Matter smart home devices are having connection problems 超かぐや姫！ BUMP OF CHICKEN feat. HATSUNE MIKU「ray」 K-Pop Demon Hunters フォールアウト シーズン２ 機動戦士ガンダム 閃光のハサウェイ キルケーの魔女 420 (cannabis culture)

Zaboravite sve što znate o procesorima: Ovako nastaje hardver koji sam 'uči' vaš softver i menja pravila igre u svetu superračunara. U prvoj epizodi serijala specijala posvećenih kompaniji Next Silicon, gost je Eyal Nagar, jedan od osnivača i potpredsednik za istraživanje i razvoj. Eyal objašnjava kako je čitavu svoju karijeru, dugu više decenija i ispunjenu radom na revolucionarnim projektima u kompanijama kao što je Intel, gradio upravo za ono što danas stvara u Next Siliconu. Razgovaramo o tome kako je nastala ideja za hardver koji se u realnom vremenu prilagođava softveru, zašto su klasični procesori i grafičke karte dostigli svoje limite i na koji način njihovo rešenje donosi revoluciju u svet superračunara i naučnih istraživanja. Eyal nas vodi kroz osmogodišnje putovanje razvoja – od prvih simulacija, preko izazova i "porođajnih muka" sa prvim čipovima, do stvaranja Maverick 2 sistema koji danas pomera granice mogućeg. Poseban deo razgovora posvećen je kancelariji u Beogradu. Otkrivamo zašto ona nije samo "još jedan" tim za podršku, već ključni deo globalne slagalice, sposoban da samostalno razvije kompletan proizvod, i kako je u Srbiji pronađen vrhunski talenat koji je neophodan za ostvarenje ovako ambiciozne vizije. Podržite nas na BuyMeACoffee: https://bit.ly/3uSBmoa Pročitajte transkript ove epizode: https://bit.ly/4abj48R Posetite naš sajt i prijavite se na našu mailing listu: http://bit.ly/2LUKSBG Prijavite se na naš YouTube kanal: http://bit.ly/2Rgnu7o Pratite Pojačalo na društvenim mrežama: FB: https://www.facebook.com/PojacaloRS/ IG: https://www.instagram.com/pojacalo.rs/ X: https://x.com/PojacaloRS LN: https://www.linkedin.com/company/pojacalo TikTok: https://www.tiktok.com/@pojacalo.rs

For the fourth and final episode of our collaboration with Wetlands Radio, a series about coastal restoration: ways we can all help repair our coast. So...what does a bottle of Two Buck Chuck and slinging back oysters have to do with building land? Find out how one man's trash transforms into coastal treasures. And then, to close out the series on coastal restoration, we learn about the crown jewel of Louisiana science: a research project that exemplifies how everything is connected. EPISODE CREDITSThis episode was hosted by Executive Producer Carlyle Calhoun and Wetlands Radio producer Eve Abrams. Wetlands Radio is produced by Eve Abrams and funded by BTNEP, the Barataria Terrebonne National Estuary Program through the Environmental Protection Agency's National Estuary Program. To hear Wetlands Radio episodes in their entirety, visit btnep.org. Sea Change is a WWNO and WRKF production. We are part of the NPR Podcast Network and distributed by PRX. Sea Change is made possible with major support from the Gulf Research Program of the National Academy of Sciences, Engineering, and Medicine. Sea Change is also supported by the Water Collaborative of Greater New Orleans. WWNO's Coastal Desk is supported by the Walton Family Foundation, the Meraux Foundation, and the Greater New Orleans Foundation. 

Send me a messageWhat if the biggest mistake in climate action is that we're still designing buildings for a climate that no longer exists?In this episode of the Climate Confident Podcast, I'm joined by David Sellers, principal architect at Hawaii Offgrid Architecture & Engineering. David designs net-zero and off-grid buildings on Maui, not as an experiment, but because the climate he's designing for is already shifting. Faster than most regulations, models, or assumptions can keep up.Buildings account for a huge share of global emissions, energy demand, and climate risk. Get the design wrong today, and we lock in higher emissions, higher costs, and lower resilience for decades. This conversation is about how to stop doing that.We dig into why designing with historical climate data is quietly undermining net zero goals, and why buildings completed today will spend most of their lives in a climate no human has experienced before. David explains how shifting wind patterns, rising temperatures, water scarcity, and fire risk are already breaking “best practice” design rules.You'll hear why off-grid no longer means uncomfortable or compromised, and how advances in solar, batteries, heat pumps, and building envelopes have changed the economics completely. We also talk about fire-resistant construction after the Lahaina fires, reusing waste surfboard foam to create ultra-insulated building blocks, and why resilience that only the wealthy can afford isn't resilience at all.This is a grounded, experience-driven look at climate tech, decarbonisation, and the energy transition, without the fantasy timelines or glossy nonsense.

In this episode of The Long Game Podcast, Alex Birkett sits down with Josh Spilker, Head of Search Marketing at AirOps, to explore how content teams are evolving in response to AI, automation, and changing search behavior. Josh draws on his background in SEO, writing, and systems thinking to outline why traditional content marketing models are breaking down and what's replacing them.They discuss the concept of content engineering, including how workflows, brand context, and AI-assisted processes change the way teams create, refresh, and scale content. The conversation also covers identity shifts for marketers, the growing complexity of search surfaces, and where real differentiation and business value are created as content production becomes easier.Key TakeawaysContent engineering represents a shift from one-off content creation to building systems that manage, update, and scale content across channels.  AI lowers the marginal cost of content, but differentiation still comes from strategy, brand context, and human editorial judgment.  Modern content teams increasingly separate roles between content strategy and content engineering, even if one person covers both in smaller orgs.  The expansion of search surfaces and longer, more contextual queries increases demand for more specific and tailored content.  As traffic becomes less reliable as a KPI, teams need to focus more on conversion quality, brand presence, and downstream business impact.Show LinksVisit AirOps on LinkedInConnect with Josh Spilker on LinkedInConnect with Alex Birkett on LinkedIn and TwitterConnect with Omniscient Digital on LinkedIn or TwitterPast guests on The Long Game podcast include: Morgan Brown (Shopify), Ryan Law (Animalz), Dan Shure (Evolving SEO), Kaleigh Moore (freelancer), Eric Siu (Clickflow), Peep Laja (CXL), Chelsea Castle (Chili Piper), Tracey Wallace (Klaviyo), Tim Soulo (Ahrefs), Ryan McReady (Reforge), and many more.Some interviews you might enjoy and learn from:Actionable Tips and Secrets to SEO Strategy with Dan Shure (Evolving SEO)Building Competitive Marketing Content with Sam Chapman (Aprimo)How to Build the Right Data Workflow with Blake Burch (Shipyard)Data-Driven Thought Leadership with Alicia Johnston (Sprout Social)Purpose-Driven Leadership & Building a Content Team with Ty Magnin (UiPath)Also, check out our Kitchen Side series where we take you behind the scenes to see how the sausage is made at our agency:Blue Ocean vs Red Ocean SEOShould You Hire Writers or Subject Matter Experts?How Do Growth and Content Overlap?Connect with Omniscient Digital on social:Twitter: @beomniscientLinkedin: Be OmniscientListen to more episodes of The Long Game podcast here: https://beomniscient.com/podcast/

In this delightfully chaotic, laugh-filled bonus episode of The Short(er) List, we dive deeper into a hot topic in proposal document creation: InDesign Books. Designers Becky Ellison and Lauren Jane Peterson unpack when and why to use them, share tips to keep you sane, confess the joys and terrors of page numbering, and honor the sacred role of the all‑powerful ‘Keeper of the Book'. They also share real‑world war stories from huge AEC proposals, swap workflow hacks, and do their best to make sense of managing multiple people editing multiple files.And because this is The Short(er) List, expect tangents including reading recommendations, animals, Lauren Jane's incredible hair, and whether InDesign files have souls. (JK… kind of). It's nerdy, it's fun, and there's something for everyone, whether you're trying to stay up on InDesign best practices or just have a laugh with MO6's graphic designers. And it makes a great companion to Episode 76: InDesign Rumble (Part 2)!

Are you maintaining your software team management like you do your car? In this week's episode of Troubleshooting Agile, Squirrel and Jeffrey use their car maintenance issues to help explore the concept of continuous monitoring versus manual checks and ask about the impact of alert fatigue. Join us to learn how you can create effective monitoring systems to prevent major issues. -------------------------------------------------- You'll find free videos and practice material, plus our book Agile Conversations, at agileconversations.com And we'd love to hear any thoughts, ideas, or feedback you have about the show: email us at info@agileconversations.com -------------------------------------------------- About Your Hosts Douglas Squirrel and Jeffrey Fredrick joined forces at TIM Group in 2013, where they studied and practised the art of management through difficult conversations. Over a decade later, they remain united in their passion for growing profitable organisations through better communication. Squirrel is an advisor, author, keynote speaker, coach, and consultant, and he's helped over 300 companies of all sizes make huge, profitable improvements in their culture, skills, and processes. You can find out more about his work here: douglassquirrel.com/index.html Jeffrey is Vice President of Engineering at ION Analytics, Organiser at CITCON, the Continuous Integration and Testing Conference, and is an accomplished author and speaker. You can connect with him here: www.linkedin.com/in/jfredrick/

In this episode of Valley of Depth, we sit down with David Tearse, co-founder and CEO of Karman Industries, to explore a piece of the AI boom that rarely gets attention: thermal infrastructure.As hyperscale data centers grow into multi-gigawatt “AI factories,” the limiting factor is no longer just chips or capital — it's how efficiently we can move and reject heat. David explains how Karman's Heat Processing Unit (HPU) reimagines cooling from first principles, bringing aerospace-grade turbomachinery and modern power electronics to a decidedly unglamorous but critical layer of the AI stack.The conversation moves from the physics of heat to the politics of data centers, and ultimately to why thermal efficiency may become a quiet national security advantage.We discuss:Why thermal management—not chips—may be the next bottleneck in the AI stackHow Karman's HPU replaces traditional chillers and dry coolers outside the data centerHow much additional compute Karman can unlock from the same power inputWhy CO₂ refrigerant de-risks data center builds from a regulatory standpointHow Karman thinks about reliability, uptime, and “aerospace-style” engineeringWhy data centers are becoming a national security issueWhere Karman could expand beyond data centers—nuclear, geothermal, and beyond…and much more.• Chapters •00:00 – Intro00:51 – Elara Nova ad01:21 – Karman Industries mascot02:28 – How would David describe himself?05:01 – The original insight that became Karman Industries06:31 – What do people underestimate about thermal management?07:26 – The story behind the name08:21 – How David and co-founder CJ Karla ended up working together11:15 – Why is now the right time to be solving thermal management?15:13 – Where does the heat go today?16:31 – Energy usage for compute vs cooling17:32 – Energy Savings with Karman's heat processing units (HPUs)18:05 – Why C02?20:48 – Replacing vs integration21:37 – Regulatory side24:42 – Karman's customer pipeline26:33 – Reliability28:59 – Engineering challenges30:39 – What comes next for Karman31:55 – Is thermal management a national security issue?33:21 – David's thoughts on rerouting heat36:23 – HPUs in space37:58 – The company culture that allows for building relaiable solutions quickly44:35 – Milestones for Karman in the next couple of years47:00 – What does David do for fun? • Show notes •Karman's website —https://www.karmanindustries.com/David's socials — https://x.com/7earseMo's socials — https://x.com/itsmoislamPayload's socials — https://twitter.com/payloadspace / https://www.linkedin.com/company/payloadspaceIgnition's socials — https://twitter.com/ignitionnuclear / https://www.linkedin.com/company/ignition-nuclear/Tectonic's socials  — https://twitter.com/tectonicdefense / https://www.linkedin.com/company/tectonicdefense/Valley of Depth archive — Listen: https://pod.payloadspace.com/ • About us •Valley of Depth is a podcast about the technologies that matter — and the people building them. Brought to you by Arkaea Media, the team behind Payload (space), Ignition (nuclear energy), and Tectonic (defense tech), this show goes beyond headlines and hype. We talk to founders, investors, government officials, and military leaders shaping the future of national security and deep tech. From breakthrough science to strategic policy, we dive into the high-stakes decisions behind the world's hardest technologies.Payload: www.payloadspace.comTectonic: www.tectonicdefense.comIgnition: www.ignition-news.com

Regina Leffers, Ph.D. is the retired Director of the Center of Excellence for the Built Environment, and Professor of Sustainable Construction for the College of Engineering at Purdue University in Fort Wayne, Indiana. Her undergraduate degrees are in Psychology and Philosophy, and her doctoral degree is in Philosophy from Purdue University. She teaches classes on consciousness and meditation and has practiced meditation since 1980. She is the author of: Sustainable Construction and Design (Pearson 2009), I Am A Miracle Magnet: (In Ten Easy Steps) (CreateSpace 2016), The Green Age: Transforming Your Life Choices for the 21st Century (Green Age Press 2011), What Is Consciousness (Regina Leffers 2019), Rethinking the Heart of Being Human (CreateSpace 2013), My Darling: Memoirs of a Buddha Girl (Regina Leffers 2023) and This Is Consciousness (Regina Leffers 2025)Interview Date: 12/5/2025Tags: Regina Leffers, consciousness, facets of consciousness, Spiral Dynamics, love and fear, gratitude practice, meditation, alpha brainwave, beta brainwaves, heart coherence, body awareness, embodiment, vagus nerve, nervous system regulation, fear to love, expanded awareness, interbeing / oneness, nature as teacher, redwood grove / big nature, personal altar of gratitude spiritual growth, self-development, unconscious patterns, emotional regulation, Personal Transformation, Psychology, Science

How did prompt engineering die so quickly? ☠️And what the heck does context engineering even mean? One of the trickiest things about LLMs is they're changing daily, yet they're the engines that drive business results. But if the engine is constantly changing, then you also have to change how you drive and the roads you take. That's why we're tackling context engineering in this installment of our Start Here Series, the essential beginners guide to understanding AI basics and growing your skills. Context Engineering: How to Get Expert-Level Outputs From AI Chatbots -- An Everyday AI Chat with Jordan WilsonNewsletter: Sign up for our free daily newsletterMore on this Episode: Episode PageJoin the discussion on LinkedIn: Thoughts on this? Join the convo on LinkedIn and connect with other AI leaders.Upcoming Episodes: Check out the upcoming Everyday AI Livestream lineupWebsite: YourEverydayAI.comEmail The Show: info@youreverydayai.comConnect with Jordan on LinkedInTopics Covered in This Episode:Evolution from Prompt to Context EngineeringWhy Prompt Engineering Is Now ObsoleteDefining Context Engineering in AI ChatbotsSix-Part Framework for Context EngineeringFour Layer System for Structuring AI ContextBuilding Reusable Context Vaults and SkillsConnecting Business Data to AI ModelsTechniques to Achieve Expert-Level AI OutputsImportance of Context Windows in Large Language ModelsContext Engineering Best Practices and ScalabilityTimestamps:00:00 "Access AI Community & Tools"03:08 "Mastering Context in AI"07:23 "Smart Models Require Less Precision"12:01 "Context Engineering Beats Prompt Engineering"15:49 "AI Context: Six Key Blocks"16:47 "Building Context for Better Results"19:53 "AI: Training, Not Easy Button"25:17 "Chain of Thought Prompting Decline"29:11 "Show, Don't Tell Techniques"32:13 "Context, Reuse, and Scalable Systems"33:19 "AI Chatbots: Memory and Skills"Keywords: context engineering, AI chatbots, expert level outputs, prompt engineering, large language models, business context, AI models, custom instructions, data access, context window, prime prompt polish, reusable context vaults, context vaults, skills file, memory enabled models, ChatGPT, Claude, Google Gemini, Microsoft Copilot, connectors, apps, searchable index, business data, personalized AI, context clues, reference material, examples, procedures, evaluation rubric, chain of thought prompting, generative AI, nondeterministic behavior, show don't tell technique, few shot examples, rubric first technique, grading criteria, output quality, scalable AI systems,Send Everyday AI and Jordan a text message. (We can't reply back unless you leave contact info) Ready for ROI on GenAI? Go to youreverydayai.com/partner 

Guest: Ted Tindersmith "I was recognized by one of the trade publications as one of the top-ranked venture capitalists in the country for 1995 to 1999 – which were good years to be good at it. I loved every day. But as I got further into it, I realized that a lot of the companies we backed were developing products and solutions to make customers far more productive. And that seems to be a really good thing. "But at a certain point, I realized that if you make a few people really productive, you may be laying off a bunch of others, which gets me to AI and why I am so focused on things today. "As I looked back on my business career, every day was really fun, but I didn't feel a sense of purpose. Now, every day, I feel a deep sense of purpose by fighting for different priorities in schools and fighting for helping kids find their strengths – instead of putting students on the narrow conveyor belt that leads right into the jaws of AI." Recommendation to listeners:  "Find the things you love to do. Be resourceful in terms of connecting your passions with ways to support yourself financially. Take chances and be bold. And leverage technology. You will never look back and you are going to be in great shape."   Ted Dintersmith is a best-selling author, education advocate, and former venture capitalist who believes math has been weaponized—and it's time to set things right. His professional career has been immersed in the world of technology-driven education, giving him a ringside seat to the advances of integrated circuits, robotics, and Artificial Intelligence. For the past fifteen years, he has focused on the world of education, forming an education non-profit, authoring best seller books, and setting a mission to help catalyze and accelerate progress in our schools and equip our children with skills and mindsets that are essential in a world defined by rapidly-advancing innovation. Ted graduated from the College of William and Mary with High Honors in English and Physics and then got a PhD in Engineering from Stanford. In 2012, he was appointed by President Obama to represent the U.S. at the United Nations General Assembly, where he focused on education and youth entrepreneurship.

The Trump administration has prioritized nuclear energy expansion, aiming to increase US nuclear capacity fourfold by 2050. This nuclear energy resurgence in the US is a rare issue with bipartisan support, and tech companies have poured billions of dollars into sustaining nuclear power plants and building new reactors to supply AI data centers. But accelerating nuclear power could mean changing environmental and safety reviews. And small modular reactors and other innovations in nuclear energy are likely years from commercial readiness.  So is there a way to reinvigorate nuclear energy in the US that's safe and fast? What would that mean for the power sector and the communities that support plants today, and future sites? Are there any signs that new technologies could address the perennial questions around nuclear safety? And what does all of this mean for national security and energy policy? Today on the show, Bill Loveless speaks with Laura S. H. Holgate, Ambassador (ret.) about the state of nuclear energy innovation, safety, and governance. Laura is the president of LSHH International Advisors and a distinguished visiting fellow at the Center on Global Energy Policy. She twice served as ambassador to the International Atomic Energy Agency. She has held multiple positions in and out of government, including vice president at the Nuclear Threat Initiative, special assistant to the president at the White House National Security Council, and a senior official at the departments of Energy and Defense.  Credits: Hosted by Jason Bordoff and Bill Loveless. Produced by Mary Catherine O'Connor, Caroline Pitman, and Kyu Lee. Engineering by Gregory Vilfranc.  

In this episode of FMI's Built-In Podcast, host Scott Winstead welcomes back Jay Bowman, senior partner and head of FMI's market research practice, for a grounded and strategic look at the U.S. construction market heading into 2026.After several years of broad-based growth, Jay explains why the conversation is shifting from chasing volume to making smarter, more disciplined decisions in a market defined by concentration, constraint and structural uncertainty. Rather than offering predictions for their own sake, the discussion focuses on what the data is really signaling and why headline numbers alone are no longer enough to guide strategy.

Founders often delay leadership coaching until a major crisis hits, leading to significant costs in productivity, team churn, and poor decisions. In this episode, James Birchler (Technical Advisor & Executive Leadership Coach) argues that early coaching is a game-changer for a startup's success. We explore the hidden costs of waiting and the benefits of intentionally installing leadership and communication systems before you scale. James shares specific self-awareness mechanisms, like advisory groups and feedback loops, to help founders design their day and create accountability. You'll also learn practical strategies like the "5-Minute Alignment Loop" for spotting communication breakdowns & for reinforcing clarity. Plus insights on how to "install your leadership OS" so it can scale with your company. ABOUT JAMES BIRCHLERJames Birchler is an executive leadership coach and technical advisor who specializes in helping engineering leaders and founders develop greater self-awareness and build high-performing teams. He combines deep technical expertise with practical leadership development, making him particularly valuable for technical leaders scaling their organizations.As both a founder and engineering leader, James has more than 20 years of experience leading teams at companies ranging from early-stage startups to Amazon, where his current role is Technical Advisor to the VP of Amazon Delivery Routing and Planning. Most recently, he founded NICER, a premium natural personal care company, and Actuate Partners, his executive coaching and technical advisory practice. He also held VP of Engineering roles at companies including Caffeine (backed by Greylock and Andreessen Horowitz), SmugMug (where his team acquired Flickr), and IMVU.At IMVU, James implemented the Lean Startup methodologies alongside Eric Ries, author of The Lean Startup and creator of the methodology, literally the first company to apply these principles. His team helped pioneer the DevOps movement by building infrastructure to ship code to production 50 times per day and coining the term "continuous deployment." This experience in systematic experimentation and continuous improvement now informs his coaching approach through frameworks like CAMS (Coaching, Advising, Mentoring, Supporting) and the Think-Do-Learn Loop.James completed his executive coaching certification at UC Berkeley Haas School of Business Executive Coaching Institute. His coaching practice focuses on self-awareness, integrity, accountability, and fostering growth mindsets that support continuous learning and high performance. He writes the Continuous Growth newsletter and offers both individual executive coaching and peer learning circles for technical leaders.Through his advisory work with growth-stage startups in the US and Europe, James helps leaders navigate common scaling challenges including hiring and interviewing, implementing development methodologies, establishing operational cadences, and developing other leaders. His approach treats leadership development like product development—with systematic feedback loops, measurable outcomes, and continuous improvement.You can find James at jamesbirchler.com, LinkedIn, and Substack. This episode is brought to you by Retool!What happens when your team can't keep up with internal tool requests? Teams start building their own, Shadow IT spreads across the org, and six months later you're untangling the mess…Retool gives teams a better way: governed, secure, and no cleanup required.Retool is the leading enterprise AppGen platform, powering how the world's most innovative companies build the tools that run their business. Over 10,000 organizations including Amazon, Stripe, Adobe, Brex, and Orangetheory Fitness use the platform to safely harness AI and their enterprise data to create governed, production-ready apps.Learn more at Retool.com/elc SHOW NOTES:Why founders should seek coaching earlier rather than waiting for a crisis to occur (2:45)The high stakes of ignoring this critical advice & how this leads to communication & scaling problems (4:50)The importance of effective communication channels & leadership mechanisms before pressure increases (6:12)How investing a small amount in coaching early on can prevent hundreds of thousands of dollars in future costs (8:07)Frameworks for cultivating self-awareness / leadership blind spots (11:06)James's practice of "designing your day" around a desired identity, not just a list of tasks (12:30)Why designing your day is about intentionality (15:13)How this practice leads to better relationships & opportunities to reflect (17:44)Reflective listening & its impact on customer relationships (19:32)Strategies for improving self-awareness / uncovering blind spots (22:05)An example of how awareness can lead to better results  (26:03)Day-to-day rituals for improving self-awareness (28:14)Signals that your communication methods are effective & getting through (30:37)Reflect on & define the desired outcome you want to generate (33:26)The five-minute alignment loop for creating clarity & confirming ownership as a leader (35:21)Why creating clarity & finding alignment is key as a founder (37:02)How the same communication & leadership patterns recur as your org scales, from small startup to large enterprise (39:46)The increasing importance of human skills like emotional intelligence and reflective listening in an age of AI (42:03)Rapid fire questions (44:38)This episode wouldn't have been possible without the help of our incredible production team:Patrick Gallagher - Producer & Co-HostJerry Li - Co-HostNoah Olberding - Associate Producer, Audio & Video Editor https://www.linkedin.com/in/noah-olberding/Dan Overheim - Audio Engineer, Dan's also an avid 3D printer - https://www.bnd3d.com/Ellie Coggins Angus - Copywriter, Check out her other work at https://elliecoggins.com/about/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Brent Daniels and bookkeeping expert Max Emory pull back the curtain on the "profit trap" that keeps many high-volume real estate investors broke. Max explains why having a massive team often feeds the ego rather than the bank account and why 2026 is the year to be "ruthless" with expenses.From the nuances of cost segregation and 100% bonus depreciation to the "wealthy person's cheat code" of living off debt instead of income, this episode is a masterclass in keeping more of what you make. Check out the TTP Training Program for more information.---------Show notes:(0:40) Beginning of today's episode (1:14) Why bookkeeping is the true foundation of a high-level real estate business (2:44) Being "ruthless" with expenses: How $90 subscriptions and "swag" eat your bottom line (4:28) Why a $10M business with a 1% profit margin is a "terrible" operation (6:05) Why solopreneurs often take home more money than companies with 20+ staff members (7:38) Utilizing depreciation to save on taxes without losing liquidity (9:59) Engineering studies, building tax basis, and the cost of implementation (13:36) How 100% bonus depreciation works for landlords in 2026 (20:44) When you should actually avoid "writing everything off" to qualify for financing (24:43) Shifting from Income - Expenses = Profit to Income - Profit = Expenses(26:19) Why you should look at P&Ls monthly and cash flow daily ----------Resources:Profit First System Follow Max on InstagramTo speak with Brent or one of our other expert coaches call (281) 835-4201 or schedule your free discovery call here to learn about our mentorship programs and become part of the TribeGo to Wholesalingincgroup.com to become part of one of the fastest growing Facebook communities in the Wholesaling space. Get all of your burning Wholesaling questions answered, gain access to JV partnerships, and connect with other "success minded" Rhinos in the community.It's 100% free to join. The opportunities in this community are endless, what are you waiting for?

You might have heard that Allied just released a new feather-light trail bike this week. The FITZ is new territory for the brand, so it seemed like a good opportunity to bring in Allied's CEO Drew Medlock and Director of Product and Engineering Sam Pickman to talk about why they decided to add a trail bike to their lineup and what makes this one so unique. They discuss the nitty-gritty specs, of course, as well as the decision-making process and behind-the-scenes debates that went into it, but they also talk about their individual journeys with the bike, from defying the aging process to Payson's religious experience on a trail he's ridden countless times. Instagram: @withpacepodcastYouTube: Payson McElveen Email: howdy@withpace.cc

Dr. Kristen Lani Rasmussen is Assistant Professor in the Department of Atmospheric Science at Colorado State University. Research in Kristen's lab focuses on studying extreme events, particularly weather events such as heavy rainfall, thunderstorms, hail storms, and other events that have a big impact on humans and society. She is interested in examining these extreme event systems in the context of our current climate and how they may change in the future. In addition to spending quality time with her fantastic family, Kristen enjoys playing jazz trumpet. She has played jazz and bluegrass music with various bands in Colorado. Kristen received her bachelor's degree in meteorology and mathematics as well as music from the University of Miami. She then attended the University of Washington where she was awarded her M.S. and Ph.D. degrees in Atmospheric Sciences. Afterwards, Kristen conducted postdoctoral research at the National Center for Atmospheric Research before joining the faculty at Colorado State University. She has received a number of awards and honors in her career, including the Peter B. Wagner Memorial Award for Women in Atmospheric Science from the Desert Research Institute, the College of the Environment Outstanding Community Impact Award from the University of Washington, and the Very Early Career Award from the American Meteorological Society's Mesoscale Processes Conference. In addition, she was recently awarded the Graduate Mentoring and Advising Award from Colorado State University as well as the George T. Abell Outstanding Early Career Faculty Award from the College of Engineering at Colorado State University. In our interview, Kristen tells us more about her life and science.

Most organizations are built to do exactly what they do…and that's the problem. When a core business starts to decay due to disruption, automation, or shifting customer demand, the instinct is to double down on efficiency, cost cutting, and short-term fixes. But that focus often crowds out the harder, riskier work of building what comes next. Nearly a decade ago, Dual Transformation offered a clear and compelling framework for this dilemma, yet nobody seems to be actually doing it. In this episode, Rodney Evans and Sam Spurlin unpack why dual transformations are so rare, why it's even harder than it sounds, and why it matters more than ever in an AI-shaped economy. They dig into the tensions between “business A” (the core) and “business B” (the future), the funding and operating system traps that kill new growth, and practical moves leaders and internal change agents can make to actually pull of two transformations at once instead of just talking about it. -------------------------------- Ready to change your organization? ⁠⁠⁠⁠⁠⁠⁠⁠Let's talk.⁠⁠⁠⁠⁠⁠⁠⁠ Get our newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sign up here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠ Follow us: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ -------------------------------- Mentioned references: Type One vs Type Two fun Enneagram 7: AWWTR Ep. 33 with Liz Orr Ulysses (book) Dual Transformation (book) Clayton Christensen and disruptive innovation taxi and uber disruption Eisenhower matrix "Squirrel" Sam's manifesto 00:00 Intro + Check-In: What's some type two fun you've had recently? 04:29 What is Dual Transformation and why now? 13:27 Sounds simple, yet deceptively hard 21:05 The 3 crisis points of a dual transformation 27:12 Recognizing when you're in a dying business 30:57 Engineering a dual transformation from the inside out 37:24 Navigating the emotions of the dying business 39:14 Idea 1: Weekly feedback routines with customers 43:07 Idea 2: Import as little as possible from the old company 45:59 Idea 3: Write the manifesto for both businesses 47:29 Bonus Idea: Read Dual Transformation! 48:26 Wrap up Sound engineering and design by Taylor Marvin of ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Coupe Studios⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

Contributor: Alec Coston, MD Educational Pearls: Disclaimer: this has nothing to do with the ER but is too cool to not talk about. Condition: Carbamoyl phosphate synthetase 1 (CPS1) deficiency Rare inborn error of metabolism Inability to properly break down ammonia Leads to severe hyperammonemia and hepatic encephalopathy Natural history: Without treatment, typically fatal within the first few weeks of life Even with current standard treatments, life expectancy is often limited to ~5–6 years Breakthrough treatment: A team of researchers at the Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania developed the CRISPR-based targeted gene therapy for this patient. First-of-its-kind precision approach tailored to the patient's specific mutation Key components of the therapy: Whole-genome sequencing to identify the exact CPS1 mutation Creation of a custom base-editing enzyme designed to correct that specific mutation Design of a guide RNA to direct the base editor to the precise genomic location Delivery method: Lipid nanoparticles used to deliver the gene-editing machinery Nanoparticles can be targeted to specific tissues Why the liver works well: CPS1 is primarily expressed in hepatocytes The liver is relatively easy to target with lipid nanoparticles Hepatocytes divide frequently, allowing edited genes to be passed on as cells replicate Long-term impact: Once edited, cells continue producing functional CPS1 enzyme Potential for durable, possibly lifelong correction from a single treatment References https://www.nih.gov/news-events/news-releases/infant-rare-incurable-disease-first-successfully-receive-personalized-gene-therapy-treatment Choi Y, Oh A, Lee Y, Kim GH, Choi JH, Yoo HW, Lee BH. Unfavorable clinical outcomes in patients with carbamoyl phosphate synthetase 1 deficiency. Clin Chim Acta. 2022 Feb 1;526:55-61. doi: 10.1016/j.cca.2021.11.029. Epub 2021 Dec 29. PMID: 34973183. Bharti N, Modi U, Bhatia D, Solanki R. Engineering delivery platforms for CRISPR-Cas and their applications in healthcare, agriculture and beyond. Nanoscale Adv. 2026 Jan 5. doi: 10.1039/d5na00535c. Epub ahead of print. PMID: 41640466; PMCID: PMC12865601. Summarized and edited by Jeffrey Olson MS4 Donate: https://emergencymedicalminute.org/donate/ Join our mailing list: http://eepurl.com/c9ouHf

In this week's FOLLOW UP, Bitcoin is down 15%, miners are unplugging rigs because paying eighty-seven grand to mine a sixty-grand coin finally failed the vibes check, and Grok is still digitally undressing men—suggesting Musk's “safeguards” remain mostly theoretical, which didn't help when X offices got raided in France. Spain wants to ban social media for kids under 16, Egypt is blocking Roblox outright, and governments everywhere are flailing at the algorithmic abyss.IN THE NEWS, Elon Musk is rolling xAI into SpaceX to birth a $1.25 trillion megacorp that wants to power AI from orbit with a million satellites, because space junk apparently wasn't annoying enough. Amazon admits a “high volume” of CSAM showed up in its AI training data and blames third parties, Waymo bags a massive $16 billion to insist robotaxis are working, Pinterest reportedly fires staff who built a layoff-tracking tool, and Sam Altman gets extremely cranky about Claude's Super Bowl ads hitting a little too close to home.For MEDIA CANDY, we've got Shrinking, the Grammys, Star Trek: Starfleet Academy's questionable holographic future, Neil Young gifting his catalog to Greenland while snubbing Amazon, plus Is It Cake? Valentines and The Rip.In APPS & DOODADS, we test Sennheiser earbuds, mess with Topaz Video, skip a deeply cursed Python script that checks LinkedIn for Epstein connections, and note that autonomous cars and drones will happily obey prompt injection via road signs—defeated by a Sharpie.IN THE LIBRARY, there's The Regicide Report, a brutal study finding early dementia signals in Terry Pratchett's novels, Neil Gaiman denying allegations while announcing a new book, and THE DARK SIDE WITH DAVE, vibing with The Muppet Show as Disney names a new CEO. We round it out with RentAHuman.ai dread relief via paper airplane databases, free Roller Coaster Tycoon, and Sir Ian McKellen on Colbert—still classy in the digital wasteland.Sponsors:DeleteMe - Get 20% off your DeleteMe plan when you go to JoinDeleteMe.com/GOG and use promo code GOG at checkout.SquareSpace - go to squarespace.com/GRUMPY for a free trial. And when you're ready to launch, use code GRUMPY to save 10% off your first purchase of a website or domain.Private Internet Access - Go to GOG.Show/vpn and sign up today. For a limited time only, you can get OUR favorite VPN for as little as $2.03 a month.SetApp - With a single monthly subscription you get 240+ apps for your Mac. Go to SetApp and get started today!!!1Password - Get a great deal on the only password manager recommended by Grumpy Old Geeks! gog.show/1passwordShow notes at https://gog.show/732FOLLOW UPBitcoin drops 15%, briefly breaking below $61,000 as sell-off intensifies, doubts about crypto growBitcoin Is Crashing So Hard That Miners Are Unplugging Their EquipmentGrok, which maybe stopped undressing women without their consent, still undresses menX offices raided in France as UK opens fresh investigation into GrokSpain set to ban social media for children under 16Egypt to block Roblox for all usersIN THE NEWSElon Musk Is Rolling xAI Into SpaceX—Creating the World's Most Valuable Private CompanySpaceX wants to launch a constellation of a million satellites to power AI needsA potential Starlink competitor just got FCC clearance to launch 4,000 satellitesAmazon discovered a 'high volume' of CSAM in its AI training data but isn't saying where it came fromWaymo raises massive $16 billion round at $126 billion valuation, plans expansion to 20+ citiesPinterest Reportedly Fires Employees Who Built a Tool to Track LayoffsSam Altman got exceptionally testy over Claude Super Bowl adsMEDIA CANDYShrinkingStar Trek: Starfleet AcademyThe RipNeil Young gifts Greenland free access to his music and withdraws it from Amazon over TrumpIs it Cake? ValentinesAPPS & DOODADSSennheiser Consumer Audio IE 200 In-Ear Audiophile Headphones - TrueResponse Transducers for Neutral Sound, Impactful Bass, Detachable Braided Cable with Flexible Ear Hooks - BlackSennheiser Consumer Audio CX 80S In-ear Headphones with In-line One-Button Smart Remote – BlackTopaz VideoEpsteinAutonomous cars, drones cheerfully obey prompt injection by road signAT THE LIBRARYThe Regicide Report (Laundry Files Book 14) by Charles StrossScientists Found an Early Signal of Dementia Hidden in Terry Pratchett's NovelsNeil Gaiman Denies the Allegations Against Him (Again) While Announcing a New BookTHE DARK SIDE WITH DAVEDave BittnerThe CyberWireHacking HumansCaveatControl LoopOnly Malware in the BuildingThe Muppet ShowDisney announces Josh D'Amaro will be its new CEO after Iger departsA Database of Paper Airplane Designs: Hours of Fun for Kids & Adults AlikeOnline (free!) version of Roller Coaster tycoon.Speaking of coasters, here's the current world champion.I am hoping this is satire...Sir Ian McKellen on Colbert.CLOSING SHOUT-OUTSCatherine O'Hara: The Grande Dame of Off-Center ComedyStanding with Sam 'Balloon Man' MartinezSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.