Podcasts about Spring

Here is the second set of the band's performance at the Forum in Inglewood California on June 4, 1977.  A long and fine set of music, luckily for us captured by a nice audience recording, results in one of the few Spring '77 shows that hasn't been commercially released.  This show features quite a few 'big' numbers - Estimated>Eyes, Terrapin, Playin in the Band, Franklin's Tower.. The Playin' sandwich is really nicely done,, as is the transitions throughout the set.  I hope you enjoy this one, my advice is to turn it up!  Grateful Dead The Forum Inglewood, CA 6/4/1977 - Saturday Two      Samson And Delilah [6:07]  Ship Of Fools [7:52]  Estimated Prophet [9:39] > Eyes Of The World [10:45] > Drums [2:#35] > Good Lovin' [5:30]  Terrapin Station [11:05] > Playing In The Band [9:40] > Franklin's Tower [10:34] > Space [3:34] > China Doll [6:09] > Not Fade Away [11:18] > Playing In The Band [3:31#] Encore      One More Saturday Night [5:12]   You can listen to this week's Deadpod here:  http://traffic.libsyn.com/deadshow/deadpod062725.mp3   My thanks for your support of the Deadpod !      

EZ off till Monday, 6/30. Enjoy two encore shows from the "Who Are These Zanes?"Notes from ep 37: Puke Voice EZ interviews Ted NugentThe show starts with Ben reviewing EZ's 12/28/93 interview with Ted Nugent.  For the first time, ever, Ted is out-douched by someone.  EZ blurts and chirps numerous guttural giggles that sound horribly un-natural as Ted rambles on about nothing.  EZ's over-the-top, puke-yelling, random "go nowhere" questions, compound this insipid, testosterone fueled, pile-of-shit to a new level of radio horror.  How EZ continued to work at any radio station with this type of shit performance for all to hear, is proof he made a deal with Lucifer himself.Next, EZ jumped 4.5 years into the future for a Spring 1998 "Joe and the Poorboy" episode.  Here, EZ was quick to insult local people in the news who lost their lives tragically.  Ep 037 of WATZ? will surely go down as one of the most cringeworthy!Notes from ep 38: Joe and the Poorboy review the Hooter's Bikini contestBen and EZ go back to early December, 1997.  Joe and the Poorboy are rockin' the tunes and throwing in snippets of painful jibber-jabber.  First, Joe and the Poorboy harass some poor Pakistani dude during the old bit, "Embassy Football Picks."Later, the boys make sure to warn everyone about icy roads, and for fat people to be extra careful, for some reason. Then, the cringe factor during the attack on fat people is surpassed with Joe and EZ's gross talk about some bikini contest at Hooter's.Finally, EZ badly insults Joe's sweet wife, for an unknown reason.All in a days work for "The Joe and the Poorboy Show!"Support this podcast at — https://redcircle.com/the-eric-zane-show-podcast/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

This week hiking savage, Will Robinson, comes back to the podcast to tell the story of his recent Spring single-season NE115. 

Pria Anand speaks to managing editor Emily Everett about her story “The Elephant's Child,” which appears in The Common's spring issue. The piece is a vivid retelling of a Hindu myth, the origin story of the elephant-headed god Ganesh. Pria talks about the process of writing and revising many versions of this ancient myth, why she felt inspired by it, and how her literary writing intersects with her career as a neurologist. Pria also discusses her debut book, The Mind Electric: A Neurologist on the Strangeness and Wonder of Our Brains, out this month from Simon & Schuster. The book explores how story and storytelling can illuminate the rich, complex gray areas within the science of the brain, weaving case study, history, fable, and memoir. Pria Anand is a neurologist and the author of The Mind Electric, out from Simon & Schuster in the U.S. and Little, Brown in the U.K. Her stories and essays have appeared in the Los Angeles Review of Books, Time Magazine, The Boston Globe, The Washington Post, The New York Times, Ploughshares, and elsewhere. She is a graduate of Yale University and Stanford Medical School, and she trained in neurology, neuro-infectious diseases, and neuroimmunology at the Johns Hopkins Hospital and the Massachusetts General Hospital. She is now an Assistant Professor of Neurology at the Boston University School of Medicine, and she cares for patients at the Boston Medical Center. ­­Read Prias's story “The Elephant's Child” in The Common at thecommononline.org/the-elephants-child. Order The Mind Electric in all formats via Simon & Schuster at simonandschuster.com/books/The-Mind-Electric/. Learn more about Pria at www.priaanand.com. The Common is a print and online literary magazine publishing stories, essays, and poems that deepen our collective sense of place. On our podcast and in our pages, The Common features established and emerging writers from around the world. Read more and subscribe to the magazine at thecommononline.org, and follow us on Instagram, Bluesky, and Facebook. Emily Everett is managing editor of the magazine and host of the podcast. Her new debut novel All That Life Can Afford is the Reese's Book Club pick for April 2025. Her work has appeared in The New York Times Modern Love column, the Kenyon Review, Electric Literature, Tin House, and Mississippi Review. She was a 2022 Massachusetts Cultural Council Fellow in Fiction. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Dr. Antonio J. Muñoz's Hitler's War Against the Partisans During The Stalingrad Offensive: Spring 1942 to the Spring of 1943 (Frontline Books, 2025) explores the brutal and widespread partisan warfare on the Eastern Front during 1942-1943, detailing the Axis forces' anti-partisan efforts and the impact on the Soviet war effort. From the start of the war on the Eastern Front, Hitler's Ostheer, his Eastern Army, and its associated forces would wage a vernichtungskrieg, or war of annihilation, in the East. Never before had such a wide-reaching campaign been fought. The preparations for the war against the partisans began before the launch of Operation Barbarossa, during which the Axis forces immediately put their plans into effect. The effects upon the newly conquered territories were soon being felt. The end of the initial phase of the German invasion of the Soviet Union was met by a Red Army winter offensive which began on 5 December 1941. As the author shows, this had repercussions behind the German lines, where the nascent Soviet partisan movement was attempting to grow and gain a foothold. By the spring of 1942 those early Soviet partisan units were ready to expand. The Germans, aware of the military situation both on the frontlines and in the rear of their armies, also prepared to counter the growing partisan threat. The partisans undoubtedly made a significant contribution to Stalin's war effort by countering Axis plans to exploit occupied Soviet territories economically, as well as providing valuable assistance to the Red Army by conducting systematic attacks against Hitler's rear communication network. As the German military planned to continue the Russian campaign into the summer of 1942, new security forces were gathered together and sent to the Soviet Union, and a new headquarters specifically organized to fight the guerrilla menace, was established. In this follow-up study, author Antonio Muñoz picks up the partisan and anti-partisan struggle in the East, where Hitler's War Against the Partisans During Operation Barbarossa left off. The struggle behind the frontlines in Russia proved to be as grand and epic as the fight along the front lines. Dr. Muñoz describes this war of attrition along the entire breath of the USSR. In 1942 the Ostheer, acting on Adolf Hitler's orders, launched their 1942 summer offensive which was aimed at capturing the Caucasus Mountains and the Russian oil fields that lay there. Dr. Muñoz not only covers the war behind the lines in every region of the occupied USSR, but also describes the German anti-partisan effort behind the lines of Army Group South, as its forces drove into the Caucasus Mountains, the Volga River bend and Stalingrad. No other work has included the guerrilla and anti-partisan struggle specific to the Stalingrad campaign. Muñoz manages to accomplish this, but also to convey the story of the rest of the partisan and anti-guerrilla war in the rest of the USSR from the spring of 1942 to the spring of 1943.Dr. Antonio J. Muñoz lives in New York City. He is a professor of history at Farmingdale State College in Long Island, New York. He is married, has two daughters and two grandchildren. His last work, published in 2018, covered the history of the German Secret Field Police in Greece, 1941-1944.Stephen Satkiewicz is an independent scholar with research areas spanning Civilizational Sciences, Social Complexity, Big History, Historical Sociology, Military History, War Studies, International Relations, Geopolitics, and Russian and East European history.Please check out my earlier interview with Dr. Antonio J. Muñoz on the previous volume in this series Hitler's War Against the Partisans During Operation Barbarossa June 1941 to the Spring of 1942 (Frontline Books, 2025) for the New Books Network.  Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

In Diddy's second attempt to secure bail while awaiting trial on sex trafficking and racketeering charges, his legal team proposed a $50 million package. This included using his mansion on Star Island as collateral and agreeing to home detention with GPS monitoring. His lawyers also suggested restrictions on visitors, limiting them to family and non-co-conspirators. Despite these conditions, the judge denied the request, citing concerns that Diddy remains a danger to the community and a potential flight risk​.Meanwhile, Diddy and his team is gearing up for their third attempt at bail after bringing on two new lawyers to help bolster the defense.    In this episode, we take a look at the second proposal given to the court by Diddy and his team.(commercial at 8:24)to contact me:bobbycapucci@protonmail.comsource:gov.uscourts.nysd.628425.13.0_7.pdf (courtlistener.com)Become a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

In Diddy's second attempt to secure bail while awaiting trial on sex trafficking and racketeering charges, his legal team proposed a $50 million package. This included using his mansion on Star Island as collateral and agreeing to home detention with GPS monitoring. His lawyers also suggested restrictions on visitors, limiting them to family and non-co-conspirators. Despite these conditions, the judge denied the request, citing concerns that Diddy remains a danger to the community and a potential flight risk​.Meanwhile, Diddy and his team is gearing up for their third attempt at bail after bringing on two new lawyers to help bolster the defense.    In this episode, we take a look at the second proposal given to the court by Diddy and his team.(commercial at 8:24)to contact me:bobbycapucci@protonmail.comsource:gov.uscourts.nysd.628425.13.0_7.pdf (courtlistener.com)Become a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

In Diddy's second attempt to secure bail while awaiting trial on sex trafficking and racketeering charges, his legal team proposed a $50 million package. This included using his mansion on Star Island as collateral and agreeing to home detention with GPS monitoring. His lawyers also suggested restrictions on visitors, limiting them to family and non-co-conspirators. Despite these conditions, the judge denied the request, citing concerns that Diddy remains a danger to the community and a potential flight risk​.Meanwhile, Diddy and his team is gearing up for their third attempt at bail after bringing on two new lawyers to help bolster the defense.    In this episode, we take a look at the second proposal given to the court by Diddy and his team.(commercial at 8:24)to contact me:bobbycapucci@protonmail.comsource:gov.uscourts.nysd.628425.13.0_7.pdf (courtlistener.com)Become a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

Sexual liberation promised freedom, but it delivered heartbreak. In this week's episode of The Narrative, we're joined by Nathanael Blake, author of Victims of the Revolution: How Sexual Liberation Hurts Us All, to candidly talk about the consequences of a culture that has abandoned God's intended design for sex, marriage, and family. CCV President Aaron Baer and Policy Director David Mahan sit down with Nathanael to walk through the damage left in the wake of the sexual revolution—how women, children, and even men have suffered under the lie that we can separate sex from commitment, family, and faithfulness. Before their conversation with Nathanael, Aaron and David break down the latest Franklin County court ruling, which claims EDChoice in Ohio is unconstitutional. They also share an update on the state budget and what's ahead for Ohio, pending Governor DeWine's signature. More about Nathanael Blake Nathanael Blake, Ph.D., is a Life and Family Initiative Fellow at the Ethics and Public Policy Center. His research interests include American political theory, Christian political thought, and the intersection of natural law and philosophical hermeneutics. His published scholarship has included work on Jean-Jacques Rousseau, Hans-Georg Gadamer, Alasdair MacIntyre, Russell Kirk, and J.R.R. Tolkien. He received an undergraduate degree in microbiology with a chemistry minor from Oregon State University. After working as a writer and editor in the pro-life movement, he enrolled in graduate studies at the Catholic University of America, earning a doctorate in political theory. As a cultural commentator, Dr. Blake has published hundreds of articles at outlets including Public Discourse, World Opinions, The Federalist, The Catholic World Report, and National Review. His first book, Victims of the Revolution: How Sexual Liberation Hurts Us All was published in the Spring of 2025. He lives in Virginia with his wife and children.

Dr. Antonio J. Muñoz's Hitler's War Against the Partisans During The Stalingrad Offensive: Spring 1942 to the Spring of 1943 (Frontline Books, 2025) explores the brutal and widespread partisan warfare on the Eastern Front during 1942-1943, detailing the Axis forces' anti-partisan efforts and the impact on the Soviet war effort. From the start of the war on the Eastern Front, Hitler's Ostheer, his Eastern Army, and its associated forces would wage a vernichtungskrieg, or war of annihilation, in the East. Never before had such a wide-reaching campaign been fought. The preparations for the war against the partisans began before the launch of Operation Barbarossa, during which the Axis forces immediately put their plans into effect. The effects upon the newly conquered territories were soon being felt. The end of the initial phase of the German invasion of the Soviet Union was met by a Red Army winter offensive which began on 5 December 1941. As the author shows, this had repercussions behind the German lines, where the nascent Soviet partisan movement was attempting to grow and gain a foothold. By the spring of 1942 those early Soviet partisan units were ready to expand. The Germans, aware of the military situation both on the frontlines and in the rear of their armies, also prepared to counter the growing partisan threat. The partisans undoubtedly made a significant contribution to Stalin's war effort by countering Axis plans to exploit occupied Soviet territories economically, as well as providing valuable assistance to the Red Army by conducting systematic attacks against Hitler's rear communication network. As the German military planned to continue the Russian campaign into the summer of 1942, new security forces were gathered together and sent to the Soviet Union, and a new headquarters specifically organized to fight the guerrilla menace, was established. In this follow-up study, author Antonio Muñoz picks up the partisan and anti-partisan struggle in the East, where Hitler's War Against the Partisans During Operation Barbarossa left off. The struggle behind the frontlines in Russia proved to be as grand and epic as the fight along the front lines. Dr. Muñoz describes this war of attrition along the entire breath of the USSR. In 1942 the Ostheer, acting on Adolf Hitler's orders, launched their 1942 summer offensive which was aimed at capturing the Caucasus Mountains and the Russian oil fields that lay there. Dr. Muñoz not only covers the war behind the lines in every region of the occupied USSR, but also describes the German anti-partisan effort behind the lines of Army Group South, as its forces drove into the Caucasus Mountains, the Volga River bend and Stalingrad. No other work has included the guerrilla and anti-partisan struggle specific to the Stalingrad campaign. Muñoz manages to accomplish this, but also to convey the story of the rest of the partisan and anti-guerrilla war in the rest of the USSR from the spring of 1942 to the spring of 1943.Dr. Antonio J. Muñoz lives in New York City. He is a professor of history at Farmingdale State College in Long Island, New York. He is married, has two daughters and two grandchildren. His last work, published in 2018, covered the history of the German Secret Field Police in Greece, 1941-1944.Stephen Satkiewicz is an independent scholar with research areas spanning Civilizational Sciences, Social Complexity, Big History, Historical Sociology, Military History, War Studies, International Relations, Geopolitics, and Russian and East European history.Please check out my earlier interview with Dr. Antonio J. Muñoz on the previous volume in this series Hitler's War Against the Partisans During Operation Barbarossa June 1941 to the Spring of 1942 (Frontline Books, 2025) for the New Books Network.  Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/military-history

Dr. Diwakar Davar and Dr. Jason Luke discuss novel agents in melanoma and other promising new data in the field of immunotherapy that were presented at the 2025 ASCO Annual Meeting. TRANSCRIPT Dr. Diwakar Davar: Hello. My name is Diwakar Davar, and I am welcoming you to the ASCO Daily News Podcast. I'm an associate professor of medicine and the clinical director of the Melanoma and Skin Cancer Program at the University of Pittsburgh's Hillman Cancer Center. Today, I'm joined by my colleague and good friend, Dr. Jason Luke. Dr. Luke is a professor of medicine. He is also the associate director of clinical research and the director of the Phase 1 IDDC Program at the University of Pittsburgh's Hillman Cancer Center. He and I are going to be discussing some key advancements in melanoma and skin cancers that were presented at the 2025 ASCO Annual Meeting. Our full disclosures are available in the transcript of this episode.  Jason, it is great to have you back on the podcast. Dr. Jason Luke: Thanks again so much for the opportunity, and I'm really looking forward to it. Dr. Diwakar Davar: Perfect. So we will go ahead and start talking a little bit about a couple of key abstracts in both the drug development immunotherapy space and the melanoma space. The first couple of abstracts, the first two, will cover melanoma. So, the first is LBA9500, which was essentially the primary results of RELATIVITY-098. RELATIVITY-098 was a phase 3 trial that compared nivolumab plus relatlimab in a fixed-dose combination against nivolumab alone for the adjuvant treatment of resected high-risk disease. Jason, do you want to maybe give us a brief context of what this is? Dr. Jason Luke: Yeah, it's great, thanks. So as almost all listeners, of course, will be aware, the use of anti–PD-1 immunotherapies really revolutionized melanoma oncology over the last 10 to 15 years. And it has become a standard of care in the adjuvant setting as well. But to review, in patients with stage III melanoma, treatment can be targeted towards BRAF with BRAF and MEK combination therapy, where that's relevant, or anti–PD-1 with nivolumab or pembrolizumab are a standard of care. And more recently, we've had the development of neoadjuvant approaches for palpable stage III disease. And in that space, if patients present, based on two different studies, either pembrolizumab or nivolumab plus ipilimumab can be given prior to surgery for somewhere in the 6- to 9-week range. And so all of these therapies have improved time-to-event endpoints, such as relapse-free or event-free survival. It's worth noting, however, that despite those advances, we've had a couple different trials now that have actually failed in this adjuvant setting, most high profile being the CheckMate-915 study, which looked at nivolumab plus ipilimumab and unfortunately was a negative study. So, with RELATIVITY-047, which was the trial of nivolumab plus relatlimab that showed an improvement in progression-free survival for metastatic disease, there's a lot of interest, and we've been awaiting these data for a long time for RELATIVITY-098, which, of course, is this adjuvant trial of LAG-3 blockade with relatlimab plus nivolumab. Dr. Diwakar Davar: Great. So with that, let's briefly discuss the trial design and the results. So this was a randomized, phase 3, blinded study, so double-blinded, so neither the investigators knew what the patients were getting, nor did the patients know what they were getting. The treatment investigational arm was nivolumab plus relatlimab in the fixed-dose combination. So that's the nivolumab standard fixed dose with relatlimab that was FDA approved in RELATIVITY-047. And the control arm was nivolumab by itself. The duration of treatment was 1 year. The patient population consisted of resected high-risk stage III or IV patients. The primary endpoint was investigator-assessed RFS. Stage and geography were the standard stratifying factors, and they were included, and most of the criteria were balanced across both arms. What we know at this point is that the 2-year RFS rate was 64% and 62% in the nivolumab and nivolumab-combination arms, respectively. The 2-year DMFS rate was similarly equivalent: 76% with nivolumab monotherapy, 73% with the combination. And similar to what you had talked about with CheckMate 915, unfortunately, the addition of LAG-3 did not appear to improve the RFS or DMFS compared to control in this patient population. So, tell us a little bit about your take on this and what do you think might be the reasons why this trial was negative? Dr. Jason Luke: It's really unfortunate that we have this negative phase 3 trial. There had been a lot of hope that the combination of nivolumab with relatlimab would be a better tolerated combination that increased the efficacy. So in the metastatic setting, we do have 047, the study that demonstrated nivolumab plus relatlimab, but now we have this negative trial in the adjuvant setting. And so as to why exactly, I think is a complicated scenario. You know, when we look at the hazard ratios for relapse-free survival, the primary endpoint, as well as the secondary endpoints for distant metastasis-free survival, we see that the hazard ratio is approximately 1. So there's basically no difference. And that really suggests that relatlimab in this setting had no impact whatsoever on therapeutic outcomes in terms of efficacy. Now, it's worth noting that there was a biomarker subanalysis that was presented in conjunction with these data that looked at some immunophenotyping, both from circulating T cells, CD8 T cells, as well as from the tumor microenvironment from patients who were treated, both in the previous metastatic trial, the RELATIVITY-047 study, and now in this adjuvant study in the RELATIVITY-098 study. And to briefly summarize those, what was identified was that T cells in advanced melanoma seemed to have higher expression levels of LAG-3 relative to T cells that are circulating in patients that are in the adjuvant setting. In addition to that, there was a suggestion that the magnitude of increase is greater in the advanced setting versus adjuvant. And the overall summary of this is that the suggested rationale for why this was a negative trial may have been that the target of LAG-3 is not expressed as highly in the adjuvant setting as it is in the metastatic setting. And so while the data that were presented, I think, support this kind of an idea, I am a little bit cautious that this is actually the reason for why the trial was negative, however. I would say we're not really sure yet as to why the trial was negative, but the fact that the hazard ratios for the major endpoints were essentially 1 suggests that there was no impact whatsoever from relatlimab. And this really makes one wonder whether or not building on anti–PD-1 in the adjuvant setting is feasible because anti–PD-1 works so well. You would think that even if the levels of LAG-3 expression were slightly different, you would have seen a trend in one direction or another by adding a second drug, relatlimab, in this scenario. So overall, I think it's an unfortunate circumstance that the trial is negative. Clearly there's going to be no role for relatlimab in the adjuvant setting. I think this really makes one wonder about the utility of LAG-3 blockade and how powerful it really can be. I think it's probably worth pointing out there's another adjuvant trial ongoing now of a different PD-1 and LAG-3 combination, and that's cemiplimab plus fianlimab, a LAG-3 antibody that's being dosed from another trial sponsor at a much higher dose, and perhaps that may make some level of difference. But certainly, these are unfortunate results that will not advance the field beyond where we were at already. Dr. Diwakar Davar: And to your point about third-generation checkpoint factors that were negative, I guess it's probably worth noting that a trial that you were involved with, KeyVibe-010, that evaluated the PD-1 TIGIT co-formulation of vibostolimab, MK-4280A, was also, unfortunately, similarly negative. So, to your point, it's not clear that all these third-generation receptors are necessarily going to have the same impact in the adjuvant setting, even if they, you know, for example, like TIGIT, and they sometimes may not even have an effect at all in the advanced cancer setting. So, we'll see what the HARMONY phase 3 trial, that's the Regeneron cemiplimab/fianlimab versus pembrolizumab control with cemiplimab with fianlimab at two different doses, we'll see how that reads out. But certainly, as you've said, LAG-3 does not, unfortunately, appear to have an impact in the adjuvant setting. So let's move on to LBA9501. This is the primary analysis of EORTC-2139-MG or the Columbus-AD trial. This was a randomized trial of encorafenib and binimetinib, which we will abbreviate as enco-bini going forward, compared to placebo in high-risk stage II setting in melanoma in patients with BRAF V600E or K mutant disease. So Jason, you know, you happen to know one or two things about the resected stage II setting, so maybe contextualize the stage II setting for us based on the trials that you've led, KEYNOTE-716, as well as CheckMate-76K, set us up to talk about Columbus-AD. Dr. Jason Luke: Thanks for that introduction, and certainly stage II disease has been something I've worked a lot on. The rationale for that has been that building off of the activity of anti–PD-1 in metastatic melanoma and then seeing the activity in stage III, like we just talked about, it was a curious circumstance that dating back about 7 to 8 years ago, there was no availability to use anti–PD-1 for high-risk stage II patients, even though the risk of recurrence and death from melanoma in the context of stage IIB and IIC melanoma is in fact similar or actually higher than in stage IIIA or IIIB, where anti–PD-1 was approved. And in that context, a couple of different trials that you alluded to, the Keynote-716 study that I led, as well as the CheckMate 76K trial, evaluated pembrolizumab and nivolumab, respectively, showing an improvement in relapse-free and distant metastasis-free survival, and both of those agents have subsequently been approved for use in the adjuvant setting by the US FDA as well as the European Medicines Agency.  So bringing then to this abstract, throughout melanoma oncology, we've seen that the impact of anti–PD-1 immunotherapy versus BRAF and MEK-targeted therapy have had very similar outcomes on a sort of comparison basis, both in frontline metastatic and then in adjuvant setting. So it was a totally reasonable question to ask: Could we use adjuvant BRAF and MEK inhibitor therapy? And I think all of us expected the answer would be yes. As we get into the discussion of the trial, I think the unfortunate circumstance was that the timing of this clinical trial being delayed somewhat, unfortunately, made it very difficult to accrue the trial, and so we're going to have to try to read through the tea leaves sort of, based on only a partially complete data set. Dr. Diwakar Davar: So, in terms of the results, they wanted to enroll 815 patients, they only enrolled 110. The RFS and DMFS were marginally improved in the treatment arm but certainly not significantly, which is not surprising because the trial had only accrued 16% to 18% of its complete accrual. As such, we really can't abstract from the stage III COMBI-AD data to stage II patients. And certainly in this setting, one would argue that the primary treatment options certainly remain either anti–PD-1 monotherapy, either with pembrolizumab or nivolumab, based on 716 or 76K, or potentially active surveillance for the patients who are not inclined to get treated.  Can you tell us a little bit about how you foresee drug development going forward in this space because, you know, for example, with HARMONY, certainly IIC disease is a part of HARMONY. We will know at least a little bit about that in this space. So what do you think about the stage IIB/C patient population? Is this a patient population in which future combinations are going to be helpful, and how would you think about where we can go forward from here? Dr. Jason Luke: It is an unfortunate circumstance that this trial could not be accrued at the pace that was necessary. I think all of us believe that the results would have been positive if they'd been able to accrue the trial. In the preliminary data set that they did disclose of that 110 patients, you know, it's clear there is a difference at a, you know, a landmark at a year. They showed a 16% difference, and that would be in line with what has been seen in stage III. And so, you know, I think it's really kind of too bad. There's really going to be no regulatory approach for this consideration. So using BRAF and MEK inhibition in stage II is not going to be part of standard practice moving into the future. To your point, though, about where will the field go? I think what we're already realizing is that in the adjuvant setting, we're really overtreating the total population. And so beyond merely staging by AJCC criteria, we need to move to biomarker selection to help inform which patients truly need the treatment. And in that regard, I don't think we've crystallized together as a field as yet, but the kinds of things that people are thinking about are the integration of molecular biomarkers like ctDNA. When it's positive, it can be very helpful, but in melanoma, we found that, unfortunately, the rates are quite low, you know, in the 10% to 15% range in the adjuvant setting. So then another consideration would be factors in the primary tumor, such as gene expression profiling or other considerations.  And so I think the future of adjuvant clinical trials will be an integration of both the standard AJCC staging system as well as some kind of overlaid molecular biomarker that helps to enrich for a higher-risk population of patients because on a high level, when you abstract out, it's just clearly the case that we're rather substantially overtreating the totality of the population, especially given that in all of our adjuvant studies to date for anti–PD-1, we have not yet shown that there's an overall survival advantage. And so some are even arguing perhaps we should even reserve treatment until patients progress. I think that's a complicated subject, and standard of care at this point is to offer adjuvant therapy, but certainly a lot more to do because many patients, you know, unfortunately, still do progress and move on to metastatic disease. Dr. Diwakar Davar: Let's transition to Abstract 2508. So we're moving on from the melanoma to the novel immunotherapy abstracts. And this is a very, very, very fascinating drug. It's IMA203. So Abstract 2508 is a phase 1 clinical update of IMA203. IMA203 is an autologous TCR-T construct targeting PRAME in patients with heavily pretreated PD-1-refractory metastatic melanoma. So Jason, in the PD-1 and CTLA-4-refractory settings, treatment options are either autologous TIL, response rate, you know, ballpark 29% to 31%, oncolytic viral therapy, RP1 with nivolumab, ORR about 30-ish percent. So new options are needed. Can you tell us a little bit about IMA203? Perhaps tell us for the audience, what is the difference between a TCR-T and traditional autologous TIL? And a little bit about this drug, IMA203, and how it distinguishes itself from the competing TIL products in the landscape. Dr. Jason Luke: I'm extremely enthusiastic about IMA203. I think that it really has transformative potential based on these results and hopefully from the phase 3 trial that's open to accrual now. So, what is IMA203? We said it's a TCR-T cell product. So what that means is that T cells are removed from a patient, and then they can be transduced through various technologies, but inserted into those T cells, we can then add a T-cell receptor that's very specific to a single antigen, and in this case, it's PRAME. So that then is contrasted quite a bit from the TIL process, which includes a surgical resection of a tumor where T cells are removed, but they're not specific necessarily to the cancer, and they're grown up in the lab and then given to the patient. They're both adoptive cell transfer products, but they're very different. One is genetically modified, and the other one is not. And so the process for generating a TCR-T cell is that patients are required to have a new biomarker that some may not be familiar with, which is HLA profiling. So the T-cell receptor requires matching to the concomitant HLA for which the peptide is bound in. And so the classic one that is used in most oncology practices is A*02:01 because approximately 48% of Caucasians have A*02:01, and the frequency of HLA in other ethnicities starts to become highly variable. But in patients who are identified to have A*02:01 genotype, we can then remove blood via leukapheresis or an apheresis product, and then insert via lentiviral transduction this T-cell receptor targeting PRAME. Patients are then brought back to the hospital where they can receive lymphodepleting chemotherapy and then receive the reinfusion of the TCR-T cells. Again, in contrast with the TIL process, however, these T cells are extremely potent, and we do not need to give high-dose interleukin-2, which is administered in the context of TIL. Given that process, we have this clinical trial in front of us now, and at ASCO, the update was from the phase 1 study, which was looking at IMA203 in an efficacy population of melanoma patients who were refractory at checkpoint blockade and actually multiple lines of therapy. So here, there were 33 patients and a response rate of approximately 50% was observed in this population of patients, notably with a duration of response approximately a year in that treatment group. And I realize that these were heavily pretreated patients who had a range of very high-risk features. And approximately half the population had uveal melanoma, which people may be aware is a generally speaking more difficult-to-treat subtype of melanoma that metastasizes to the liver, which again has been a site of resistance to cancer immunotherapy. So these results are extremely promising. To summarize them from what I said, it's easier to make TCR-T cells because we can remove blood from the patient to transduce the T cells, and we don't have to put them through surgery. We can then infuse them, and based on these results, it looks like the response rate to IMA203 is a little bit more than double what we expect from lifileucel. And then, whereas with lifileucel or TILs, we have to give high-dose IL-2, here we do not have to give high-dose IL-2. And so that's pretty promising. And a clinical trial is ongoing now called the SUPREME phase 3 clinical trial, which is hoping to validate these results in a randomized global study. Dr. Diwakar Davar: Now, one thing that I wanted to go over with you, because you know this trial particularly well, is what you think of the likelihood of success, and then we'll talk a little bit about the trial design. But in your mind, do you think that this is a trial that has got a reasonable likelihood of success, maybe even a high likelihood of success? And maybe let's contextualize that to say an alternative trial, such as, for example, the TebeAM trial, which is essentially a T-cell bispecific targeting GP100. It's being compared against SOC, investigator's choice control, also in a similarly heavily pretreated patient population. Dr. Jason Luke: So both trials, I think, have a strong chance of success. They are very different kinds of agents. And so the CD3 bispecific that you referred to, tebentafusp, likely has an effect of delaying progression, which in patients with advanced disease could have a value that might manifest as overall survival. With TCR-T cells, by contrast, we see a very high response rate with some of the patients going into very durable long-term benefit. And so I do think that the SUPREME clinical trial has a very high chance of success. It will be the first clinical trial in solid tumor oncology randomizing patients to receive a cell therapy as compared with a standard of care. And within that standard of care control arm, TILs are allowed as a treatment. And so it will also be the first study that will compare TCR-T cells against TILs in a randomized phase 3. But going back to the data that we've seen in the phase 1 trial, what we observe is that the duration of response is really connected to the quality of the response, meaning if you have more than a 50% tumor shrinkage, those patients do very, very well. But even in patients who have less than 50% tumor shrinkage, the median progression-free survival right now is about 4.5 months. And again, as we think about trial design, standard of care options for patients who are in this situation are unfortunately very bad. And the progression-free survival in that population is probably more like 2 months. So this is a trial that has a very high likelihood of being positive because the possibility of long-term response is there, but even for patients who don't get a durable response, they're likely going to benefit more than they would have based on standard chemotherapy or retreatment with an anti–PD-1 agent. Dr. Diwakar Davar: Really, a very important trial to enroll, a trial that is first in many ways. First of a new generation of TCR-T agents, first trial to look at cell therapy in the control arm, a new standard of efficacy, but potentially also if this trial is successful, it will also be a new standard of trial conduct, a new kind of trial, of a set of trials that will be done in the second-line immunotherapy-refractory space. So let's pivot to the last trial that we were going to discuss, which was Abstract 2501. Abstract 2501 is a first-in-human phase 1/2 trial evaluating BNT142, which is the first-in-class mRNA-encoded bispecific targeting Claudin-6 and CD3 in patients with Claudin-positive tumors. We'll talk a little bit about this, but maybe let's start by talking a little bit about Claudin-6. So Claudin-6 is a very interesting new target. It's a target that's highly expressed in GI and ovarian tumors. There are a whole plethora of Claudin-6-targeting agents, including T-cell bispecifics and Claudin-6-directed CAR-Ts that are being developed. But BNT142 is novel. It's a novel lipid nanoparticle LNP-encapsulated mRNA. The mRNA encodes an anti–Claudin-6 CD3 bispecific termed RiboMAB-021. And it then is administered to the patient. The BNT142-encoding mRNA LNPs are taken up by the liver and translated into the active drug. So Jason, tell us a little bit about this agent. Why you think it's novel, if you think it's novel, and let's talk a little bit then about the results. Dr. Jason Luke: So I certainly think this is a novel agent, and I think this is just the first of what will probably become a new paradigm in oncology drug development. And so you alluded to this, but just to rehash it quickly, the drug is encoded as genetic information that's placed in the lipid nanoparticle and then is infused into the patient. And after the lipid nanoparticles are taken up by the liver, which is the most common place that LNPs are usually taken up, that genetic material in the mRNA starts to be translated into the actual protein, and that protein is the drug. So this is in vivo generation, so the patient is making their own drug inside their body. I think it's a really, really interesting approach. So for any drug that could be encoded as a genetic sequence, and in this case, it's a bispecific, as you mentioned, CD3-Claudin-6 engager, this could have a tremendous impact on how we think about pharmacology and novel drug development moving into the future in oncology. So I think it's an extremely interesting drug, the like of which we'll probably see only more moving forward. Dr. Diwakar Davar: Let's maybe briefly talk about the results. You know, the patient population was heavily pretreated, 65 or so patients, mostly ovarian cancer. Two-thirds of the patients were ovarian cancer, the rest were germ cell and lung cancer patients. But let's talk a little bit about the efficacy. The disease control rate was about 58% in the phase 1 population as a whole, but 75% in the ovarian patient population. Now tell us a little bit about the interesting things about the drug in terms of the pharmacokinetics, and also then maybe we can pivot to the clinical activity by dose level. Dr. Jason Luke: Well, so they did present in their presentation at ASCO a proportionality showing that as higher doses were administered, that greater amounts of the drug were being made inside the patient. And so that's an interesting observation, and it's an important one, right? Suggesting that the pharmacology that we classically think of by administering drugs by IV, for example, would still be in play. And that did translate into some level of efficacy, particularly at the higher dose levels. Now, the caveat that I'll make a note of is that disease control rate is an endpoint that I think we have to be careful about because what that really means is sometimes a little bit unclear. Sometimes patients have slowly growing tumors and so on and so forth. And the clinical relevance of disease control, if it doesn't last at least 6 months, I think is probably pretty questionable. So I think these are extremely interesting data, and there's some preliminary sense that getting the dose up is going to matter because the treatment responses were mostly observed at the highest dose levels. There's also a caveat, however, that across the field of CD3 bispecific molecules like this, there's been quite a bit of heterogeneity in terms of the response rate, with some of them only really generating stable disease responses and other ones having more robust responses. And so I think this is a really interesting initial foray into this space. My best understanding is this molecule is not moving forward further after this, but I think that this really does set it up to be able to chase after multiple different drug targets on a CD3 bispecific backbone, both in ovarian cancer, but then basically across all of oncology. Dr. Diwakar Davar: Perfect. This is a very new sort of exciting arena where we're going to be looking at, in many ways, these programmable constructs, whether we're looking at in vivo-generated, in this case, a T-cell bispecific, but we've also got newer drugs where we are essentially giving drugs where people are generating in vivo CAR T, and also potentially even in vivo TCR-T. But certainly lots of new excitement around this entire class of drugs. And so, what we'd like to do at this point in time is switch to essentially the fact that we've got a very, very exciting set of data at ASCO 2025. You've heard from Dr. Luke regarding the advances in both early drug development but also in advanced cutaneous melanoma. And Jason, as always, thank you so much for sharing your very valuable and great, fantastic insights with us on the ASCO Daily News Podcast. Dr. Jason Luke: Well, thanks again for the opportunity. Dr. Diwakar Davar: And thank you to our listeners for taking your time to listen today. You will find the links to the abstracts that we discussed today in the transcript of this episode. And finally, if you value the insights that you hear on the ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Follow today's speakers:    Dr. Diwakar Davar    @diwakardavar    Dr. Jason Luke @jasonlukemd Follow ASCO on social media:     @ASCO on Twitter       ASCO on Bluesky   ASCO on Facebook       ASCO on LinkedIn   Disclosures:     Dr. Diwakar Davar:      Honoraria: Merck, Tesaro, Array BioPharma, Immunocore, Instil Bio, Vedanta Biosciences     Consulting or Advisory Role: Instil Bio, Vedanta Biosciences     Consulting or Advisory Role (Immediate family member): Shionogi     Research Funding: Merck, Checkmate Pharmaceuticals, CellSight Technologies, GSK, Merck, Arvus Biosciences, Arcus Biosciences     Research Funding (Inst.): Zucero Therapeutics     Patents, Royalties, Other Intellectual Property: Application No.: 63/124,231 Title: COMPOSITIONS AND METHODS FOR TREATING CANCER Applicant: University of Pittsburgh–Of the Commonwealth System of Higher Education Inventors: Diwakar Davar Filing Date: December 11, 2020 Country: United States MCC Reference: 10504-059PV1 Your Reference: 05545; and Application No.: 63/208,719 Enteric Microbiotype Signatures of Immune-related Adverse Events and Response in Relation to Anti-PD-1 Immunotherapy     Dr. Jason Luke:     Stock and Other Ownership Interests: Actym Therapeutics, Mavu Pharmaceutical, Pyxis, Alphamab Oncology, Tempest Therapeutics, Kanaph Therapeutics, Onc.AI, Arch Oncology, Stipe, NeoTX     Consulting or Advisory Role: Bristol-Myers Squibb, Merck, EMD Serono, Novartis, 7 Hills Pharma, Janssen, Reflexion Medical, Tempest Therapeutics, Alphamab Oncology, Spring Bank, Abbvie, Astellas Pharma, Bayer, Incyte, Mersana, Partner Therapeutics, Synlogic, Eisai, Werewolf, Ribon Therapeutics, Checkmate Pharmaceuticals, CStone Pharmaceuticals, Nektar, Regeneron, Rubius, Tesaro, Xilio, Xencor, Alnylam, Crown Bioscience, Flame Biosciences, Genentech, Kadmon, KSQ Therapeutics, Immunocore, Inzen, Pfizer, Silicon Therapeutics, TRex Bio, Bright Peak, Onc.AI, STipe, Codiak Biosciences, Day One Therapeutics, Endeavor, Gilead Sciences, Hotspot Therapeutics, SERVIER, STINGthera, Synthekine     Research Funding (Inst.): Merck , Bristol-Myers Squibb, Incyte, Corvus Pharmaceuticals, Abbvie, Macrogenics, Xencor, Array BioPharma, Agios, Astellas Pharma , EMD Serono, Immatics, Kadmon, Moderna Therapeutics, Nektar, Spring bank, Trishula, KAHR Medical, Fstar, Genmab, Ikena Oncology, Numab, Replimmune, Rubius Therapeutics, Synlogic, Takeda, Tizona Therapeutics, Inc., BioNTech AG, Scholar Rock, Next Cure     Patents, Royalties, Other Intellectual Property: Serial #15/612,657 (Cancer Immunotherapy), and Serial #PCT/US18/36052 (Microbiome Biomarkers for Anti-PD-1/PD-L1 Responsiveness: Diagnostic, Prognostic and Therapeutic Uses Thereof)     Travel, Accommodations, Expenses: Bristol-Myers Squibb, Array BioPharma, EMD Serono, Janssen, Merck, Novartis, Reflexion Medical, Mersana, Pyxis, Xilio

Dr. Antonio J. Muñoz's Hitler's War Against the Partisans During The Stalingrad Offensive: Spring 1942 to the Spring of 1943 (Frontline Books, 2025) explores the brutal and widespread partisan warfare on the Eastern Front during 1942-1943, detailing the Axis forces' anti-partisan efforts and the impact on the Soviet war effort. From the start of the war on the Eastern Front, Hitler's Ostheer, his Eastern Army, and its associated forces would wage a vernichtungskrieg, or war of annihilation, in the East. Never before had such a wide-reaching campaign been fought. The preparations for the war against the partisans began before the launch of Operation Barbarossa, during which the Axis forces immediately put their plans into effect. The effects upon the newly conquered territories were soon being felt. The end of the initial phase of the German invasion of the Soviet Union was met by a Red Army winter offensive which began on 5 December 1941. As the author shows, this had repercussions behind the German lines, where the nascent Soviet partisan movement was attempting to grow and gain a foothold. By the spring of 1942 those early Soviet partisan units were ready to expand. The Germans, aware of the military situation both on the frontlines and in the rear of their armies, also prepared to counter the growing partisan threat. The partisans undoubtedly made a significant contribution to Stalin's war effort by countering Axis plans to exploit occupied Soviet territories economically, as well as providing valuable assistance to the Red Army by conducting systematic attacks against Hitler's rear communication network. As the German military planned to continue the Russian campaign into the summer of 1942, new security forces were gathered together and sent to the Soviet Union, and a new headquarters specifically organized to fight the guerrilla menace, was established. In this follow-up study, author Antonio Muñoz picks up the partisan and anti-partisan struggle in the East, where Hitler's War Against the Partisans During Operation Barbarossa left off. The struggle behind the frontlines in Russia proved to be as grand and epic as the fight along the front lines. Dr. Muñoz describes this war of attrition along the entire breath of the USSR. In 1942 the Ostheer, acting on Adolf Hitler's orders, launched their 1942 summer offensive which was aimed at capturing the Caucasus Mountains and the Russian oil fields that lay there. Dr. Muñoz not only covers the war behind the lines in every region of the occupied USSR, but also describes the German anti-partisan effort behind the lines of Army Group South, as its forces drove into the Caucasus Mountains, the Volga River bend and Stalingrad. No other work has included the guerrilla and anti-partisan struggle specific to the Stalingrad campaign. Muñoz manages to accomplish this, but also to convey the story of the rest of the partisan and anti-guerrilla war in the rest of the USSR from the spring of 1942 to the spring of 1943.Dr. Antonio J. Muñoz lives in New York City. He is a professor of history at Farmingdale State College in Long Island, New York. He is married, has two daughters and two grandchildren. His last work, published in 2018, covered the history of the German Secret Field Police in Greece, 1941-1944.Stephen Satkiewicz is an independent scholar with research areas spanning Civilizational Sciences, Social Complexity, Big History, Historical Sociology, Military History, War Studies, International Relations, Geopolitics, and Russian and East European history.Please check out my earlier interview with Dr. Antonio J. Muñoz on the previous volume in this series Hitler's War Against the Partisans During Operation Barbarossa June 1941 to the Spring of 1942 (Frontline Books, 2025) for the New Books Network.  Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/german-studies

Dr. Antonio J. Muñoz's Hitler's War Against the Partisans During The Stalingrad Offensive: Spring 1942 to the Spring of 1943 (Frontline Books, 2025) explores the brutal and widespread partisan warfare on the Eastern Front during 1942-1943, detailing the Axis forces' anti-partisan efforts and the impact on the Soviet war effort. From the start of the war on the Eastern Front, Hitler's Ostheer, his Eastern Army, and its associated forces would wage a vernichtungskrieg, or war of annihilation, in the East. Never before had such a wide-reaching campaign been fought. The preparations for the war against the partisans began before the launch of Operation Barbarossa, during which the Axis forces immediately put their plans into effect. The effects upon the newly conquered territories were soon being felt. The end of the initial phase of the German invasion of the Soviet Union was met by a Red Army winter offensive which began on 5 December 1941. As the author shows, this had repercussions behind the German lines, where the nascent Soviet partisan movement was attempting to grow and gain a foothold. By the spring of 1942 those early Soviet partisan units were ready to expand. The Germans, aware of the military situation both on the frontlines and in the rear of their armies, also prepared to counter the growing partisan threat. The partisans undoubtedly made a significant contribution to Stalin's war effort by countering Axis plans to exploit occupied Soviet territories economically, as well as providing valuable assistance to the Red Army by conducting systematic attacks against Hitler's rear communication network. As the German military planned to continue the Russian campaign into the summer of 1942, new security forces were gathered together and sent to the Soviet Union, and a new headquarters specifically organized to fight the guerrilla menace, was established. In this follow-up study, author Antonio Muñoz picks up the partisan and anti-partisan struggle in the East, where Hitler's War Against the Partisans During Operation Barbarossa left off. The struggle behind the frontlines in Russia proved to be as grand and epic as the fight along the front lines. Dr. Muñoz describes this war of attrition along the entire breath of the USSR. In 1942 the Ostheer, acting on Adolf Hitler's orders, launched their 1942 summer offensive which was aimed at capturing the Caucasus Mountains and the Russian oil fields that lay there. Dr. Muñoz not only covers the war behind the lines in every region of the occupied USSR, but also describes the German anti-partisan effort behind the lines of Army Group South, as its forces drove into the Caucasus Mountains, the Volga River bend and Stalingrad. No other work has included the guerrilla and anti-partisan struggle specific to the Stalingrad campaign. Muñoz manages to accomplish this, but also to convey the story of the rest of the partisan and anti-guerrilla war in the rest of the USSR from the spring of 1942 to the spring of 1943.Dr. Antonio J. Muñoz lives in New York City. He is a professor of history at Farmingdale State College in Long Island, New York. He is married, has two daughters and two grandchildren. His last work, published in 2018, covered the history of the German Secret Field Police in Greece, 1941-1944.Stephen Satkiewicz is an independent scholar with research areas spanning Civilizational Sciences, Social Complexity, Big History, Historical Sociology, Military History, War Studies, International Relations, Geopolitics, and Russian and East European history.Please check out my earlier interview with Dr. Antonio J. Muñoz on the previous volume in this series Hitler's War Against the Partisans During Operation Barbarossa June 1941 to the Spring of 1942 (Frontline Books, 2025) for the New Books Network.  Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/russian-studies

Locally produced, hand-crafted, small batch, non-GMO, organic (or maybe silicon-based?) foods are often touted as the pinnacle of health and nutrition. So, please enjoy this selection of small indie visual novel we're bringing you today, freshly delivered for your consumption. You simply will not find this level of toxic yuri, this high a concentration of charm and potency, or a mouthfeel anywhere near as satisfying in those visual novels you get at the big box grocery stores. They do sell them at grocery stores, right? This metaphor falls apart completely otherwise. This month, Sara and Runa embark upon their fifth Indie Visual Novel Compilation Track episode! Every six months, our hosts select a heaping handful of Indie VNs that they've read and enjoyed to tell you, dear listener, about the joys and delights you can find in indie games. Many of our entries this time are also from very cool Game Jams, and looking through the catalog of a jam's entries can be a great way to find more games to satisfy your cravings. In these Indie Game Compilation Track episodes we want to highlight some of the incredible indie VNs we've played recently and get people excited about the things happening in Indie Visual Novel development spaces. We want to not only showcase the amazing breadth of work coming from Indie developers but also talk about some of our favorite games, many of which touch on subjects, characters, and experiences we rarely get the chance to see in games from larger studios. You can find a list of each game we played below and we encourage you to play along with us, and go searching for other Indie visual novels as well!  Most of these games are free and if not, fairly cheap (though please tip the creators if you are able), and you can read most of them inside of an hour or two. In fact, we want YOU, dear listener, to pick at least one of these games to play after you listen, and then tell us about it! You can also check our Patreon, where listeners and patrons can submit either a short audio clip or a few sentences telling us about an Indie VN you've played and enjoyed recently! We may even include your submission on our next Indie VN Compilation Track episode (only if you want, that is). Games discussed in this episode:Comme Tu Veux (00:06:23) Our Bad Ending (00:18:33)Spring in Her Step (00:22:41)Threads of Magic (00:28:18) her tears were my light (00:39:02)A Circle of Charity (00:43:13)Neurokino Retrograde (00:48:32) Märchen Line (01:01:14)A Date with Death (01:16:38)The Final Prize is Soup (01:26:25)Good Lord! Everyone at the Reunion for my Religious All-Girls School is a Trans Man... And they're Hot?! (01:40:11)And also, these two Listeners submissions!Pinfeather - Submitted by Emrys (00:33:21)Murders on the Yangtze River - Submitted by Raven (00:58:57)

In this episode, Hailey ventures just beyond the trees in Lincoln County! This Wisconsin wonderland offers four seasons of fun. Looking for outdoor recreation? How about endless relaxation? Lincoln County checks all the boxes and more! Start exploring now…The Bobber is brought to you by Something Special from Wisconsin: https://www.somethingspecialwi.com/Read the blog here: https://discoverwisconsin.com/four-seasons-of-fun-in-lincoln-county/Camp New Wood County Park: https://www.co.lincoln.wi.us/forestry-land-and-parks/page/camp-new-wood; Merrill: https://www.merrillchamber.org/; Ice Age Trail: https://www.iceagetrail.org/; Tomahawk: https://www.tomahawkchamber.com/; Three Stone Arch Bridge: https://ci.merrill.wi.us/?SEC=5972A1FF-AD01-450A-805B-17E3FA030AE8&DE=39F5BCF2-0A05-456D-991D-014CC02FA1B6; Johnson's of Merrill: https://www.facebook.com/p/Johnsons-of-Merrill-100057627962823/; Music in the Square: https://www.facebook.com/GazeboNightsAtNormalPark/; Sawmill Brewing Company: https://sawmillbrewing.net/; Helene's Hilltop Orchard: https://www.heleneshilltoporchard.com/; Iron Bull Thunderdown in the Underdown: https://www.ironbull.org/underdown-details; Harrison Hills ATV Trails: https://www.harrisonhillsatvclub.com/; Winding Trail Grill & Bar: https://www.windingtrailbar.com/grill/; Northwoods Fall Ride: https://northwoodsfallride.com/; Merrill Ice Drags: https://merrillicedraggersinc.mypixieset.com/; Lincoln County - What's Behind the Trees: Lincoln County - What's Behind the TreesThe Bobber: https://discoverwisconsin.com/the-bobber-blog/The Cabin Podcast: https://the-cabin.simplecast.com. Follow on social @thecabinpodShop Discover Wisconsin: shop.discoverwisconsin.com. Follow on social @shopdiscoverwisconsinDiscover Wisconsin: https://discoverwisconsin.com/. Follow on social @discoverwisconsinDiscover Mediaworks: https://discovermediaworks.com/. Follow on social @discovermediaworksLincoln County: https://www.co.lincoln.wi.us/

Join hosts Brent Bodkin and Quaysie Gordon Maule for the third episode of FPF First and Goal, where they break down the latest matchups, standout performances, and storylines from the Spring 2025 season.

Dirk and Bradley Dammerman of Idaho Whitetail Guides catch up on Bradley's Spring bear season, and then take a deep dive into a conservation organization that Bradley jus started: North Idaho Houndsmen Association. They talk about conserving the animals hound hunters love to pursue. They also talk about issues Hunting Outfitters here in Idaho are facing with the new tag drawing system nonresidents will face in 2026. Connect with Jason, Dirk, and Phelps Game Calls MeatEater on Instagram, Facebook, Twitter, Youtube, and Youtube Clips Subscribe to The MeatEater Podcast Network on YouTube Shop Phelps MerchSee omnystudio.com/listener for privacy information.

Tune-in as the PU crew discuss their remaining thoughts from the Patriots 2025 Spring workouts. They take a glimpse at the past and share the moments in Patriots history that solidified them as Patriots fans and which moments they had the best experiences as a fan. Plus, they talk vacationing, chicken breast, seasoning and more!See omnystudio.com/listener for privacy information.

Spring cleaning in the summer? Mikah Sargent and Rosemary Orchard roll up their sleeves to tackle both physical and digital device maintenance, sharing expert tips for getting your Apple gear spotless inside and out. Physical iPhone cleaning - Apple's official recommendations for safe disinfecting using 70% isopropyl alcohol wipes and Clorox wipes, while avoiding bleach and hydrogen peroxide that can damage device coatings Specialized cleaning tools - iFixit's Precision Cleaning Kit featuring tiny brushes, foam-tipped swabs, and contact cleaner for getting into speaker grills and ports Digital decluttering - MacPaw's app CleanMyPhone uses AI to find duplicate photos, similar shots, and organize camera rolls while supporting Ukrainian developers Mass app deletion strategy - Using Apple Configurator to quickly remove unused apps in bulk, with Rosemary demonstrating how she went from 827 apps to a more manageable number AirPods deep cleaning - Apple's specific instructions for cleaning earwax buildup using micellar water and distilled water to break down waxes without damaging the mesh speakers Case and accessory maintenance - Importance of removing iPhone cases regularly to clean both the device and case interior, plus organizing charging cables in labeled mesh bags Cable management and recycling - Tips for checking cable condition, proper storage solutions, and donating old chargers to homeless shelters for those still using older devices News Control Center transparency - Apple reduced the transparency to minimize distractions while maintaining the glass aesthetic Safari interface tweaks - Tab bar repositioned to the bottom for better usability after user feedback App Store accessibility section - New feature allowing developers to specify supported accessibility features on product pages Enhanced Wallet tracking - Siri can now scan emails for package tracking from any merchant, not just Apple Pay purchases Call transcription updates - Feature renamed to "save call transcripts" with clearer notifications that all participants will be informed before recording begins Feedback VoiceOver PDF accessibility - Johnny, a blind user, seeks alternatives to Adobe Acrobat for filling PDF forms, highlighting ongoing accessibility issues with major software companies and poorly designed PDF forms Shortcuts Corner HomeKit automation limitations - Bjorn's question about combining multiple triggers (window open/close) into single automations reveals fundamental HomeKit restrictions that require separate automations for each trigger Hosts: Mikah Sargent and Rosemary Orchard Contact iOS Today at iOSToday@twit.tv. Download or subscribe to iOS Today at https://twit.tv/shows/ios-today Want access to the ad-free video and exclusive features? Become a member of Club TWiT today! https://twit.tv/clubtwit Club TWiT members can discuss this episode and leave feedback in the Club TWiT Discord.

Spring cleaning in the summer? Mikah Sargent and Rosemary Orchard roll up their sleeves to tackle both physical and digital device maintenance, sharing expert tips for getting your Apple gear spotless inside and out. Physical iPhone cleaning - Apple's official recommendations for safe disinfecting using 70% isopropyl alcohol wipes and Clorox wipes, while avoiding bleach and hydrogen peroxide that can damage device coatings Specialized cleaning tools - iFixit's Precision Cleaning Kit featuring tiny brushes, foam-tipped swabs, and contact cleaner for getting into speaker grills and ports Digital decluttering - MacPaw's app CleanMyPhone uses AI to find duplicate photos, similar shots, and organize camera rolls while supporting Ukrainian developers Mass app deletion strategy - Using Apple Configurator to quickly remove unused apps in bulk, with Rosemary demonstrating how she went from 827 apps to a more manageable number AirPods deep cleaning - Apple's specific instructions for cleaning earwax buildup using micellar water and distilled water to break down waxes without damaging the mesh speakers Case and accessory maintenance - Importance of removing iPhone cases regularly to clean both the device and case interior, plus organizing charging cables in labeled mesh bags Cable management and recycling - Tips for checking cable condition, proper storage solutions, and donating old chargers to homeless shelters for those still using older devices News Control Center transparency - Apple reduced the transparency to minimize distractions while maintaining the glass aesthetic Safari interface tweaks - Tab bar repositioned to the bottom for better usability after user feedback App Store accessibility section - New feature allowing developers to specify supported accessibility features on product pages Enhanced Wallet tracking - Siri can now scan emails for package tracking from any merchant, not just Apple Pay purchases Call transcription updates - Feature renamed to "save call transcripts" with clearer notifications that all participants will be informed before recording begins Feedback VoiceOver PDF accessibility - Johnny, a blind user, seeks alternatives to Adobe Acrobat for filling PDF forms, highlighting ongoing accessibility issues with major software companies and poorly designed PDF forms Shortcuts Corner HomeKit automation limitations - Bjorn's question about combining multiple triggers (window open/close) into single automations reveals fundamental HomeKit restrictions that require separate automations for each trigger Hosts: Mikah Sargent and Rosemary Orchard Contact iOS Today at iOSToday@twit.tv. Download or subscribe to iOS Today at https://twit.tv/shows/ios-today Want access to the ad-free video and exclusive features? Become a member of Club TWiT today! https://twit.tv/clubtwit Club TWiT members can discuss this episode and leave feedback in the Club TWiT Discord.

Spring cleaning in the summer? Mikah Sargent and Rosemary Orchard roll up their sleeves to tackle both physical and digital device maintenance, sharing expert tips for getting your Apple gear spotless inside and out. Physical iPhone cleaning - Apple's official recommendations for safe disinfecting using 70% isopropyl alcohol wipes and Clorox wipes, while avoiding bleach and hydrogen peroxide that can damage device coatings Specialized cleaning tools - iFixit's Precision Cleaning Kit featuring tiny brushes, foam-tipped swabs, and contact cleaner for getting into speaker grills and ports Digital decluttering - MacPaw's app CleanMyPhone uses AI to find duplicate photos, similar shots, and organize camera rolls while supporting Ukrainian developers Mass app deletion strategy - Using Apple Configurator to quickly remove unused apps in bulk, with Rosemary demonstrating how she went from 827 apps to a more manageable number AirPods deep cleaning - Apple's specific instructions for cleaning earwax buildup using micellar water and distilled water to break down waxes without damaging the mesh speakers Case and accessory maintenance - Importance of removing iPhone cases regularly to clean both the device and case interior, plus organizing charging cables in labeled mesh bags Cable management and recycling - Tips for checking cable condition, proper storage solutions, and donating old chargers to homeless shelters for those still using older devices News Control Center transparency - Apple reduced the transparency to minimize distractions while maintaining the glass aesthetic Safari interface tweaks - Tab bar repositioned to the bottom for better usability after user feedback App Store accessibility section - New feature allowing developers to specify supported accessibility features on product pages Enhanced Wallet tracking - Siri can now scan emails for package tracking from any merchant, not just Apple Pay purchases Call transcription updates - Feature renamed to "save call transcripts" with clearer notifications that all participants will be informed before recording begins Feedback VoiceOver PDF accessibility - Johnny, a blind user, seeks alternatives to Adobe Acrobat for filling PDF forms, highlighting ongoing accessibility issues with major software companies and poorly designed PDF forms Shortcuts Corner HomeKit automation limitations - Bjorn's question about combining multiple triggers (window open/close) into single automations reveals fundamental HomeKit restrictions that require separate automations for each trigger Hosts: Mikah Sargent and Rosemary Orchard Contact iOS Today at iOSToday@twit.tv. Download or subscribe to iOS Today at https://twit.tv/shows/ios-today Want access to the ad-free video and exclusive features? Become a member of Club TWiT today! https://twit.tv/clubtwit Club TWiT members can discuss this episode and leave feedback in the Club TWiT Discord.

Spring cleaning in the summer? Mikah Sargent and Rosemary Orchard roll up their sleeves to tackle both physical and digital device maintenance, sharing expert tips for getting your Apple gear spotless inside and out. Physical iPhone cleaning - Apple's official recommendations for safe disinfecting using 70% isopropyl alcohol wipes and Clorox wipes, while avoiding bleach and hydrogen peroxide that can damage device coatings Specialized cleaning tools - iFixit's Precision Cleaning Kit featuring tiny brushes, foam-tipped swabs, and contact cleaner for getting into speaker grills and ports Digital decluttering - MacPaw's app CleanMyPhone uses AI to find duplicate photos, similar shots, and organize camera rolls while supporting Ukrainian developers Mass app deletion strategy - Using Apple Configurator to quickly remove unused apps in bulk, with Rosemary demonstrating how she went from 827 apps to a more manageable number AirPods deep cleaning - Apple's specific instructions for cleaning earwax buildup using micellar water and distilled water to break down waxes without damaging the mesh speakers Case and accessory maintenance - Importance of removing iPhone cases regularly to clean both the device and case interior, plus organizing charging cables in labeled mesh bags Cable management and recycling - Tips for checking cable condition, proper storage solutions, and donating old chargers to homeless shelters for those still using older devices News Control Center transparency - Apple reduced the transparency to minimize distractions while maintaining the glass aesthetic Safari interface tweaks - Tab bar repositioned to the bottom for better usability after user feedback App Store accessibility section - New feature allowing developers to specify supported accessibility features on product pages Enhanced Wallet tracking - Siri can now scan emails for package tracking from any merchant, not just Apple Pay purchases Call transcription updates - Feature renamed to "save call transcripts" with clearer notifications that all participants will be informed before recording begins Feedback VoiceOver PDF accessibility - Johnny, a blind user, seeks alternatives to Adobe Acrobat for filling PDF forms, highlighting ongoing accessibility issues with major software companies and poorly designed PDF forms Shortcuts Corner HomeKit automation limitations - Bjorn's question about combining multiple triggers (window open/close) into single automations reveals fundamental HomeKit restrictions that require separate automations for each trigger Hosts: Mikah Sargent and Rosemary Orchard Contact iOS Today at iOSToday@twit.tv. Download or subscribe to iOS Today at https://twit.tv/shows/ios-today Want access to the ad-free video and exclusive features? Become a member of Club TWiT today! https://twit.tv/clubtwit Club TWiT members can discuss this episode and leave feedback in the Club TWiT Discord.

In Spring 2025, a coalition of organizers in St. Louis, Missouri launched a campaign with international scope, targeting corporations implicated in the Gaza genocide.

Welcome to another episode of the podcast! Several times a year, outlets like Eater, Food Network, Epicurious, Publishers Weekly, and others publish their roundup features: What's hot in cookbooks this season? They're the pulse checks of the cookbook world and offer a lens into what's resonating now. Today on the show, we'll dive into trends in cookbooks published this spring, each tied to what cookbook buyers are craving and what publishers are publishing in Spring 2025. Things We Mention in This Episode: Join the waitlist for Cookbooks on KDP for September 2025

Spring eats winter, winter eats pod. Grab your drumsticks and meet us in the woods to chat about mothers, daughters, and apex predators in Hellbender.  If you break our hearts, we'll devour you. If you like the podcast, please rate, review, and subscribe! Follow us at @theladykpod on Twitter and @theladykillerspod on Instagram and Bluesky Connect with your co-hosts:  Jenn: @jennferatu on Twitter, Instagram, Threads, and Bluesky   Sammie: @srkdall on Twitter and Instagram, @srkdallreads Bookstagram Cover Art: David (@the_haunted_david, @the_haunted_david_art) Logo Art: Meg (@sludgework) Music: McKenzie Gerber (@wolfman_mac_gerber) Learn more about your ad choices. Visit megaphone.fm/adchoices

Jenna Stauffer (@JennaStaufferkeywest) examines the real estate reality facing many homebuyers right now: elevated mortgage rates, higher insurance, higher taxes and weakened consumer confidence. She says a lot of buyers are "moving forward with caution" and "taking their time" before making any moves. She says high home prices are actually helping bring unsold inventory up, which could put pressure on prices. Jenna says buyers have an opportunity now to negotiate with sellers, something that hasn't existed in years.======== Schwab Network ========Empowering every investor and trader, every market day.Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – / schwabnetwork Follow us on Facebook – / schwabnetwork Follow us on LinkedIn - / schwab-network About Schwab Network - https://schwabnetwork.com/about

Composer Steve Reich is one of the most influential musicians of modern times. In the 1960s he helped rewrite the rules of composition, using analogue tape machines to experiment with rhythm, repetition and syncopation. As the godfather of musical minimalism, his influence on Philip Glass, David Bowie, Jonny Greenwood of Radiohead, and many other composers, has been enormous. Countless dance music producers also owe a debt to pieces including It's Gonna Rain, Drumming, Different Trains and Music for 18 Musicians. His music has been performed in concert halls all around the world, and his many awards include three Grammys, a Pulitzer Prize, the Polar Prize for Music and the Premium Imperiale. Steve Reich tells John Wilson how, at the age of 14, three very different recordings awoke his interest in music: Stravinsky's The Rite of Spring, Bach's 5th Brandenburg Concerto, and a piece of bebop jazz featuring saxophonist Charlie Parker, trumpeter Miles Davis and drummer Kenny Clarke. Inspired to start a jazz quintet of his own, Reich began to study percussion before enrolling in a music history course at Cornell University. It was here he discovered the music of Pérotin, the 12th century French composer associated with the Notre Dame school of polyphony in Paris. His beautiful sustained harmonies had a profound influence on Reich's own compositions, including Four Organs (1970) and Music for 18 Musicians (1976).Steve Reich also explains the significance of two books on his music; Studies in African Music by A.M.Jones and Music in Bali by Colin McPhee, both of which led to a greater understanding of music from parts of the world where music is passed down aurally rather than through notation.Producer: Edwina Pitman Additional recording: Laura Pellicer

Selvom verden fortsat ser ‘rodet’ ud, synes de globale investorer at være relativt - måske ligefrem overraskende - positive. Millionærklubben vejrer argumenterne for op- og nedadgående aktier herfra og debatterer, hvilke sektorer og selskaber, det er værd at satse på. I studiet giver Jacob Asmussen og Anders Christoffersen fra Investment Panel Aarhus deres syn på de aktuelle markeder og Jyske Banks senior aktiestrateg, Michelle Nørgaard, har blikket rettet mod dagens aktuelle nyheder og åbningsniveauer. Vært: Bodil Johanne GantzelSee omnystudio.com/listener for privacy information.

Justin Invites The Athletics Dan Duggan onto the show to talk about the Giants Spring Workouts. From Carter becoming a star, does the coaching staff have any hope for Evan Neal, and what will the team do with Jalin HyattFollow Dan Duggan here for more:https://x.com/DDuggan21https://www.nytimes.com/athletic/author/dan-duggan/00:00 Dan Duggan Talks Giants Spring Workouts02:40 Dan Duggan Joins The Show!04:12 Abdul Carter Is going to be a star14:50 Still hope for Evan Neal20:20 Nabers Toe Injury24:30 Banks vs Flott for CB229:45 Hyatts expectations38:00 Update on Dart47:00 Daboll & Dart50:00 Trading Winston52:50 Players Standing outUse code GIANTS2025 for 10% off your next SeatGeek order*: https://seatgeek.onelink.me/RrnK/GIAN.... Sponsored by SeatGeek. *Restrictions apply. Max $20 discountCheck out our Merch: https://shop.jomboymedia.com/collections/talkin-giantsSubscribe to JM Football for our NFL coverage: https://www.youtube.com/@JMFootballSubscribe to the JM Newsletter: http://jomboymedia.com/email#giants #nygiants

Subscribe to our newsletter to get this amazing report: Refuting the Top 5 Gay Myths https://ruthinstitute.org/refute-the-top-five-myths/ In this conversation, Nathanael Blake discusses his book 'Victims of the Revolution: How Sexual Liberation Hurts Us All,' exploring the implications of the sexual revolution on society, particularly focusing on the harm it has caused to children and families. He argues for the superiority of Christian sexual ethics and critiques the notion of sexual liberation, emphasizing the need for authentic love and commitment in relationships. The discussion also touches on the political context surrounding transgender issues and the failures of modern political philosophy to address the needs of children. Nathanael Blake, Ph.D., is a Fellow at the Ethics and Public Policy Center, focusing on American political theory, Christian political thought, and natural law. He holds a doctorate in political theory from the Catholic University of America, where he wrote on the relationship between natural law and history. Dr. Blake has taught political science and was a Richard M. Weaver Fellow. His commentary has appeared in Public Discourse, The Federalist, National Review, and more. His forthcoming book, Victims of the Revolution: How Sexual Liberation Hurts Us All, will be published by Ignatius Press in Spring 2025.   Victims of the Revolution: How Sexual Liberation Hurts Us All - Ethics & Public Policy Center: https://eppc.org/book/victims-of-the-revolution-how-sexual-liberation-hurts-us-all/ Send this book to: Campus Ministers, Christian Educators, Pastors, Deacons, Elders in Various Christian Congregations, Bible Study Leaders, and receptive people.   Watch the full episode, uncensored, on Rumble: https://rumble.com/user/Theruthinstitute Subscribe to our YouTube playlist: @RuthInstitute  Follow us on Social Media: https://www.instagram.com/theruthinstitute https://twitter.com/RuthInstitute https://www.facebook.com/TheRuthInstitute/ https://theruthinstitute.locals.com/newsfeed  

Oak trees have a very particular sound this time of year. It's to do with the leaves. Their texture, shape and contours. How they catch and filter the breeze. On a warm spring day, like this one the Lento box captured last month in rural Shropshire, you can hear the softness of the moving air sonified by banks of oak leaves. The scene around the microphone box, tied to the trunk of a relatively young oak tree, is endlessly rural. Ahead, over a bank thick with tangled shrubs, a wide field, vibrant green, is dotted with sheep and lambs. Song birds sing out from around the small nature reserve. A place called Poles Coppice. A point on the landscape with many neatly hidden well occupied perches. Birds are like nothing else. Their songs illuminate dusky shadows between the trees. And carry far. Over fields, bathed in late afternoon sun. And sheep, dutifully grazing   * Poles Coppice nature reserve is quite remote and has a lovely sound-feel, thanks to its resident birds and oak trees. the country road that can sometimes be heard mid-left of scene (far distant) leads to a small town called Minsterley. When that day last month we set out to capture the spring sound of Shropshire we auditioned various locations before eventually stumbling upon this particularly peaceful little place. Thank you to the guardians of Poles Coppice who created this nature reserve. We are so glad to be able to share its natural sound. 

What happens when the miraculous feels both ordinary and overwhelming? In I Dreamed of Oil, a short story from the Spring 2025 issue of Dialogue: A Journal of Mormon Thought, author Theric Jepson recounts a… The post I Dreamed of Oil by Theric Jepson: Audio Story appeared first on Dialogue Journal.

To begin the week, Oracle announced the Oracle Defense Ecosystem, a first-of-its-kind global initiative to redefine the delivery of defense and government technology innovations. In other news, Certinia announced its Spring '25 release, loaded with features meant to give customer more foresight, flexibility, and intelligence. Finally, Nextworld unveiled 25.1, its first release of the year. Customers can expect major enhancements to the platform's AI capabilities.Connect with us!https://www.erpadvisorsgroup.com866-499-8550LinkedIn:https://www.linkedin.com/company/erp-advisors-groupTwitter:https://twitter.com/erpadvisorsgrpFacebook:https://www.facebook.com/erpadvisorsInstagram:https://www.instagram.com/erpadvisorsgroupPinterest:https://www.pinterest.com/erpadvisorsgroupMedium:https://medium.com/@erpadvisorsgroup

Listen to today's podcast... Some days when things are so hectic, I forget where I am supposed to be or I leave important notes and items back at my office. I struggle daily with trying not to be a perfectionist.  Sometimes my total focus is on family issues and I haven't tackled any of the jobs on my desk.  Other times when I am so pressured to meet a deadline, that even saying good night to my family seems too much of a distraction. There are habits and strategies that I use to keep me, and my family organized, and to maintain my health.  My afternoon nap allows me to recoup from my working day and gear up for my evenings spent teaching karate. Spring and summer are my favourite time of year and there is nothing better than a day spent away from my office gardening, cutting the grass, or just sitting on the patio.  Take One Action Today To Build Your #Resiliency!      So Here are today's Tips For Building Resiliency and Celebrating Rebuild Your Life Month: Finding the right balance is important for ourselves and for our organizations. Life is busy and often we are pulled in many directions.  Balance is not about equality in all areas of life.  It is about making choices and living in a way in which you feel motivated and satisfied with the way your life is going. If your life is not exactly how you want it to be, take the time to rethink your strategies and look for ways to rebuild your resiliency. Remember, If you like today's wellness tips, let me know. You can leave me a review on amazon or through your #alexa app. Discover how to take small steps towards a healthier, happier, less-stressed you by visiting my website at worksmartlivesmart.com #mentalhealth #hr

Today on City Beat, I am talking with Nevada Police Chief Casey Crain. We will be discussing the Nevada Animal Shelter. The Chief will talk about the current status of the animal shelter and what's being done to fix the flood damage incurred from Spring storms. Chief Crain will report on the current condition of the shelter's animals. Finally, we'll talk about how the animal shelter may be closed to visitors, but is still open to pet adoption.

With Torres on vacation - our College Hoops "Off-Season Grades" rolls on but with a twist - today we talk St. John's with a special guest as the NY Post's Zach Braziller talks the Red Storm! The guys talk this year's Big East title, what it's like covering Rick Pitino and the Johnnies ABSURD 2026 roster - is SJU a true title contender?! Listen to BYU's off-season grade - HERE Listen to Kentucky's off-season grade - HERE⁠ ⁠Listen to NC State's off-season grade - HERE⁠⁠ ⁠⁠⁠Listen to North Carolina's off-season grade - HERE⁠⁠⁠ ⁠⁠⁠Listen to UConn's off-season grade - HERE⁠ Fioboc is giving listeners of the Aaron Torres Pod 20% on their next purchase - for their FULL STORE of beautiful new clothes: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Check out their entire store here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Also, thank you to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Caulipuffs, the healthy, yet delicious snack⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ that is taking over your grocery isle! For more details - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠visit CauliPuffs.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠! Learn more about your ad choices. Visit megaphone.fm/adchoices

Joe's Premium Subscription: www.standardgrain.comGrain Markets and Other Stuff Links-Apple PodcastsSpotifyTikTokYouTubeFutures and options trading involves risk of loss and is not suitable for everyone.

This week on Dates & Mates, Damona Hoffman rewinds to her 400th episode featuring a guest who helped inspire the show from the start: the legendary Dr. Drew Pinsky. Dr. Drew has spent decades giving love, sex, and mental health advice on Loveline, Celebrity Rehab, and now on his podcast Ask Dr. Drew, which he co-hosts with his wife of over 30 years. In this vulnerable and heartfelt episode, Dr. Drew shares his personal journey through a seven-year on-and-off courtship, what finally made him ready for commitment, and how he and his wife maintain a strong marriage after decades together. Plus, he joins Damona to answer your dating questions in a special extended Dear Damona segment. What you'll learn: Why emotional readiness matters more than "the one" How to navigate on-again/off-again dynamics with clarity When to disclose a medical condition or disability to a new partner Why gratitude and daily check-ins are key to long-term love What makes someone feel "unapproachable" in dating and how to shift it How to know when you're ready to date after trauma or burnout This episode is part of our Rewind Series, where we revisit some of the most timeless and transformative conversations from the Dates & Mates archive. Subscribe now to catch every Rewind drop and our Spring bonus episodes the moment they go live. Listen to more of Dr. Drew on the Ask Dr. Drew podcast and follow him @drdrewpinsky. Learn more about your ad choices. Visit megaphone.fm/adchoices

Patreon: https://www.patreon.com/c/miccheckwaifuwaifu   Episodes of the week: To Be Hero X, Evil Lord of a Galactic Empire   Rascal Does Not Dream of Bunny Girl Senpai   Old Country Bumpkin   Lazarus/Once Upon a Witches Death   The Brilliant Healers New Life in the Shadows   Unaware Atelier Meister   Can this boy-girl relationship survive   WindBreakers Season 2   Shoshimin Season 2   Get to Know MCWW? Favorite anime director?   Review of The Too-Perfect Saint: Tossed Aside by My Fiance and Sold to Another Kingdom https://anilist.co/anime/183275/The-TooPerfect-Saint-Tossed-Aside-by-My-Fianc-and-Sold-to-Another-Kingdom/   Animation: Polow - 7 Telliano: 7.5 Sound Design: Polow - 8 Telliano - 8 Pacing: Polow - 9.5 Telliano - 8.5 Plot: Polow - 9.5 Telliano - 10 Characters: Polow - 9.5 Telliano - 9.5   Too-Perfect Saint Spoilers  

This is the Spring 2025 Rundown, where we discuss these 3 shows!1) Windbreaker Season 2 2) Lazarus3) One Piece: Egghead Arc To join the Discord, follow us on our socials (we're on Threads / Insta, Twitter (X), Bluesky / Hive and Tumblr): https://Linktree.com/animedegensInterested in watch parties? We're going to start hosting some in our Discord! So join up and join us! The Degen Videos are on YouTube & Spotify now! So, Make sure you follow and like the videos over there at https://Linktree.com/animedegensPlease Rate us on your listening platforms and don't forget to tell your anime friends about us! its the best way to support us and we really do appreciate y'all! Thanks for listening!!If you have any Feedback that you'd like to share or have Topics that you'd like for us to discuss on the Degen Episode, Please reach out to us on any of our Socials, Discord or click here! Interested in being a guest? Reach out to Tyler on Discord or Twitter / Threads!Time Stamps:Intro: 00:00Windbreaker Season 2 Episode 12 (Finale) : 05:40Lazarus Episode 12 : 23:50One Piece Episode - Break Hosted on Acast. See acast.com/privacy for more information.

Join Dan Vega with special guest Dan Dobrin, App Architect at Google, as they explore enterprise-ready Spring AI development using Google Gemini models. This episode covers the latest Spring AI features, caching strategies, unified SDK capabilities, and AI agents—moving beyond simple demos to real-world production implementations. Learn how to build fast, enterprise-grade AI applications with Spring and Google's powerful Gemini models.Show Notes:Dan Dobrin on Twitter / XDan Dobrin on LinkedInBuilding Agentic AI the Google Way: MCP + A2A + ADK for JavaGoogle Cloud and Spring AI 1.0

In this powerful episode of Bible Reading and Coffee Drinking, we walk through Matthew 27—the darkest chapter in the Gospel, yet one filled with incredible purpose. Jesus is betrayed, condemned, mocked, and ultimately crucified. But even in the midst of pain, rejection, and death, God's plan for salvation unfolds. This chapter reminds us of the cost of grace and the depth of Jesus' love for us. Grab your Bible and coffee, and let's reflect on the cross, the sacrifice, and the hope that was born through it all.Also, use the code "Podcast20" to get 20% off our entire store. This is a special code specifically for our podcast listeners! See all our our hoodies, t-shirts, caps and more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.livingchristian.org/store.html⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Check out this podcast and all previous episodes on Spotify, iTunes, YouTube and more! - https://www.livingchristian.org/podcast.htmlNEW DEVOTIONAL: 30 Days With The Lord, A Living Christian Devotional: https://amzn.to/4eXAO7sMY BIBLE: Every Man's Bible: New Living Translation - Find it here: https://amzn.to/3MuDAUSCHECK OUT OUR WEBSITE BELOW FOR CHRISTIAN APPAREL, PRODUCTS, BLOGS, BIBLE VERSES AND MORE:Website | https://www.livingchristian.orgStore | https://www.livingchristian.org/store.htmlPodcast | https://www.livingchristian.org/podcast.htmlFOLLOW ME ON SOCIAL:Instagram | https://www.instagram.com/living_christian/Facebook | https://www.facebook.com/livechristian1 Twitter | https://twitter.com/livechristian1Pinterest | https://www.pinterest.com/living_christian/TikTok | https://www.tiktok.com/@livingchristianABOUT US:Living Christian believes that our Christian faith isn't just for Sunday mornings in Church. Our faith impacts every aspect of our lives and the challenges we face every day of the week. We want to connect to people who are seeking to determine what Living Christian means in their own day-to-day lives. We are focused on providing resources and products to a community of believers. We provide daily biblical inspiration, motivation and guidance through social posts, blogs and Christian apparel and products.This work contains Music Track The 126ers - Winds of Spring that is licensed under a Creative Commons Attribution license. Source: https://directory.audio/free-music/pop/5092-the-126ers-winds-of-springAuthor: The 126ers#christ #christian #christianity #christianblog #christianblogger #verses #bible #bibleinspiration #bibletime #jesusistheway #biblestudy #dailybible #newtestament #oldtestament #thebible #christ #jesuschrist #holybible #lukewarm #christians #christianpodcast #christmas

Is the Mets offense a problem this season? Can the Knicks solidify their bench? Chris'd Off about a lack of Spring weather this year. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Alex Barth of 98.5 The Sports Hub and Brian Hines of Pats Pulpit go LIVE for a post spring practice Q&A! SUBSCRIBE to the Patriots Beat Podcast ⤵️

In this episode we talk about the upcoming season and shows we are excited for. then we do our impression on Lazarus, Kowloon Generic Romance, and Uchuujin MuuMuu. Email us at Animefridge@gmail.com

Summer is arriving with a vengeance in the northern part of the globe, so it's a bit odd to be going back a season... and yet, we regret it not, as we open up the pages of Rites of Spring. This supplement for Changeling: the Lost 1e is a compendium of magics and Glamour, folklore and rumor, all of it steeped in the eponymous Court's energy of desire. In a sense, that emotion underlies the principle of magic to begin with: the desire to reshape the world as one wishes. But fae being fae, such workings are as treacherous as they are beautiful. We're looking at new Contracts, mystically-flavored Merits and Flaws, a thorough treatment of dream interpretation, and more scandalous ways to manipulate the Hedge than you can shake a stick at (if that's your idea of a good time). Like all the other books for the line we've examined so far, this one is dense with ideas, so bear with us as we navigate its primrose paths. And mind how the way seems to shift as you walk it, leading where you did not expect... ...but where you might indeed expect to be led is, first to the page for your own purchase of the book, namely, https://www.storytellersvault.com/product/54401?affiliate_id=3063731, and thereafter to our usual cross-platform Hollow: Discord: https://discord.me/ctp Email: podcast@changelingthepodcast.com Facebook: https://www.facebook.com/profile.php?id=100082973960699 Mastodon: https://dice.camp/@ChangelingPod Patreon: https://www.patreon.com/changelingthepodcast YouTube: https://www.youtube.com/@ChangelingThePodcast your hosts Pooka G (any pronoun/they) regains one point of any given day's lost Clarity with each shot of espresso consumed the next morning. Amelia Fetch (she/her) tried to write a poem where everything rhymed around "hobgoblin", but every single attempt was NSFW. Nitimur in vetitum semper, cupimusque negata. [We are always striving for things forbidden, and coveting those denied us.] —Ovid, Amorum, III.iv.17

Our guest argues that looking back on those who came before us can help us understand who we are and why we do the things we do. Plus, a very special request from Dan. Spring Washam is a well-known teacher, author, and visionary leader based in Oakland, California. She is the author of A Fierce Heart: Finding Strength, Courage and Wisdom in Any Moment and her newest book, The Spirit of Harriet Tubman: Awakening from the Underground. Spring is considered a pioneer in bringing mindfulness-based meditation practices to diverse communities. She is one of the founding teachers at the East Bay Meditation Center, located in downtown Oakland, CA and has practiced and studied Buddhist philosophy in both the Theravada and Tibetan schools of Buddhism since 1999. In this episode we talk about: How Spring came to write about Harriet Tubman's life Her work with plant medicine and the shamanic tradition The dream and the “conversations” Spring had with Tubman Why we are all so interested in ancestry How we can deepen our relationship with our ancestors Family Constellation Therapy as a modality for doing ancestry work Spring's own family history Why she is still processing the experience of writing her book about Harriet Tubman What she means by the “inner underground railroad” and how it is alive today And, how, in the inner underground railroad, freedom equates to nirvana  Content Warning: mentions of suicide This episode originally aired in February 2023, and we're re-airing it today for two reasons: first, because it's awesome; and second, because Spring needs help.  A few months ago, Spring was hit by a delivery truck while crossing the street in Atlanta. She suffered extensive injuries and has been largely unable to work since then. As a result, she's been experiencing some financial distress between her mounting medical bills and her inability to be fully employed.  We've teamed up with the meditation teachers Jack Kornfield and Trudy Goodman to start a GoFundMe page to help Spring raise a little bit of money. Jack, Trudy and Dan have all contributed. If you can make a contribution, please do. No amount is too small.  You can find the GoFundMe here: https://www.gofundme.com/f/support-spring-washams-healing-journey   Related Episodes: The Dharma of Harriet Tubman | Spring Washam Spring Washam, ‘What Was Creating All This Suffering?' Everything You Wanted To Know About Meditation Retreats But Were Afraid To Ask | Spring Washam (And Dan's Close Friend, Zev Borow)   Join Dan's online community here Follow Dan on social: Instagram, TikTok Subscribe to our YouTube Channel To advertise on the show, contact sales@advertisecast.com or visit https://advertising.libsyn.com/10HappierwithDanHarris.  

Hello sunshine! How do you enter a new day? Do you slowly stretch into it, or do you immediately plug in to dopamine via technology and screens? Join Camille and Luis as they discuss how living seasonally and cyclically can be supportive and resourcing to our bodies. At one time everyone lived in tandem with the seasons.  Caffeine and electricity allowed our ancestors to break their own boundaries and nature's boundaries (of seasons, light, and temperature). This evolved into the dissociative "go go go crash" cycle, causing us to ignore the fatigue and exhaustion. Culturally this looks like overreach, personally it looks like burnout. Contributing to this mindset is the overcoupling of depression with the minimalism and stillness of winter. However, Fall and Winter are not about death, but about energy conservation in preparation for the productive seasons of Spring and Summer.  Join us as we harness the energy of the sun on Saturday, June 28, 2025 at 12pm EDT for a webinar where we sink more in to this juicy topic. When is your season of wintering in a year, month, and day? When is your season of rebirth and productivity in a year, month, and day? You can register for the webinar here: https://www.holisticlifenavigation.com/events/living-seasonally-cyclically-how-i-recovered-from-burnoutYou can read more about, and register for, the Living Seasonally & Cyclically webinar here: https://www.holisticlifenavigation.com/events/living-seasonally-cyclically-how-i-recovered-from-burnout You can read more about, and register for, the 6-month Embodied Nutrition group here: https://www.holisticlifenavigation.com/slow-practice-nutrition-group----You can learn more on the website: https://www.holisticlifenavigation.com/ Learn more about the self-led course here: https://www.holisticlifenavigation.com/self-led-new Join the waitlist to pre-order Luis' book here: https://www.holisticlifenavigation.com/the-book You can follow Luis on Instagram @holistic.life.navigationQuestions? You can email us at info@holisticlifenavigation.com

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Jason and Dirk get back together again after a busy spring and shoot the breeze about their bear hunts. Jason and close friend Tyson, hunt bears in Idaho. Dirk hunted black bears in the great state of Alaska on an invite from Christensen Arms. They discuss the highs and lows of bear hunting and throw in a few bear hunting tips. Connect with Jason, Dirk, and Phelps Game Calls MeatEater on Instagram, Facebook, Twitter, Youtube, and Youtube Clips Subscribe to The MeatEater Podcast Network on YouTube Shop Phelps MerchSee omnystudio.com/listener for privacy information.