Podcasts about thiazides

Special guest Luke Laffin, MD, FACC, the Co-Director, Center for Blood Pressure Disorders with the Department of Cardiovascular Medicine at the Cleveland Clinic joins us to talkabout first-line meds for hypertension.Listen in as they discuss nuances regarding selection of a first-line medication for the treatment of hypertension.You'll also hear practical advice from panelists on TRC's Editorial Advisory Board:Andrea Darby Stewart, MD, Associate Director, Honor Health Family Medicine Residency Program and Clinical Professor of Family, Community & Occupational Medicine at the University of Arizona College of Medicine - PhoenixDouglas S. Paauw, MD, MACP, Professor of Medicine at the University of Washington School of MedicineFor the purposes of disclosure, Dr. Luke Laffin reports relevant financial relationships with CRISPR Therapeutics [hyperlipidemia], Eli Lilly [obesity], Medtronic [hypertension] (honorarium); Arrowhead [hyperlipidemia], AstraZeneca [hyperlipidemia], Mineralys Therapeutics [hypertension] (grants/research support).The other speakers have nothing to disclose. All relevant financial relationships have been mitigated.TRC Healthcare offers CE credit for this podcast. Log in to your Pharmacist's Letter or Prescriber Insights account and look for the title of this podcast in the list of available CE courses.The clinical resources mentioned during the podcast are part of a subscription to Pharmacist's Letter and Prescriber Insights: Chart: Treatment of HypertensionChart: Angiotensin Receptor Blockers and Angiotensin-Converting Enzyme InhibitorsChart: Comparison of Calcium Channel BlockersChart: Comparison of Commonly Used DiureticsIf you're not yet a Pharmacist's Letter or Prescriber Insights subscriber, find out more about our product offerings at trchealthcare.com. Follow or subscribe, rate, and review this show in your favorite podcast app. You can also reach out to provide feedback or make suggestions by emailing us at ContactUs@trchealthcare.com.

The First Principles of Prescribing Antihypertensives that can get you through your GP rotations: What are they? When do you use them? How do you tell a patient about them? === Other Links === Check out our new website ⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes. Check out our Instagram: ⁠⁠⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠⁠⁠ Recorded 4 April 2023 Co-hosts: Jason D'Silva & Daniel Bontempto feat. Nhien Huynh & Fan Tang. Produced by Joshua Naylor & Adian Izwan. If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠⁠⁠hello@1pm.wiki⁠⁠⁠⁠⁠ *** We're really excited to be collaborating with Becky from Becky's notes, a UK based resource, to produce infographics for our visual learners out there. Becky's notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks. You can check her out on Instagram at @beckysnotes01 and get her books at ⁠⁠⁠⁠⁠https://linktr.ee/Beckysnotes⁠⁠⁠⁠⁠ === Timestamps === (00:45) The First Principles of HTN (06:03) GASSDETH (08:32) Stratifying risk (10:02) The DRUGS (11:02) ACEi (14:23) ARBs (17:10) Thiazides (17:43) CCBs (20:03) BBlockers (23:34) Summary  (23:49) Combinations (24:56) The Triple Whammy (27:20) Medication Counselling  (31:26) Four Key Takeaways  

Objective: Determine the significance and clinical use of Prostate Specific Antigen in clinical practice   Lab Test Name: Prostate Specific Antigen – PSA   Description: Measurement of PSA in the bloodstream Used to diagnose and assess prostate health, size and function.   Indications: Evaluate: Enlarged prostate when prostate cancer is suspected Stage cancer Effectiveness of treatments   Normal Therapeutic Values: Normal –  Male: < 4 ng/mL  Female: < 0.5 ng/mL Collection:  Serum Separator Tube   What would cause increased levels? Increased: Benign Prostatic Hypertrophy (BPH) Prostate cancer Prostatitis Urinary retention   What would cause decreased levels? Decreased: Long-term use of NSAIDs- explained in part by the anti-inflammatory effect of these medications Thiazides- reduces bioavailable testosterone, associated with resulting in functional hypogonadism Statins- cholesterol plays a role in synthesis of androgen, which affects the size of the prostate 5-alpha-reductase inhibitors- due to the effect on prostate size.

Today we have special guest, Dr. Sarah Gilligan, a nephrologist, to talk about the new study of thiazides for kidney stones. We all learn in medical school that thiazides reduce urinary excretion of calcium, but does that really translate to fewer kidney stones? We also have Dr. Brian Locke on to talk about the CAPE COD trial, a big new critical care paper on using hydrocortisone in severe pneumonia, as well as the latest COPD guidelines and a retrospective study of oral antibiotics for infective endocarditis. Check it out! Hydrochlorothiazide for Kidney StonesSteroids for Pneumonia Meta-analysisHydrocortisone for Severe CAP (CAPE COD)2023 GOLD COPD GuidelinesReal World Use of Oral Antibiotics for EndocarditisMusic from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R

Get a free nursing lab values cheat sheet at NURSING.com/63labs   Objective: Determine the significance and clinical use of Prostate Specific Antigen in clinical practice   Lab Test Name: Prostate Specific Antigen – PSA   Description: Measurement of PSA in the bloodstream Used to diagnose and assess prostate health, size and function.   Indications: Evaluate: Enlarged prostate when prostate cancer is suspected Stage cancer Effectiveness of treatments   Normal Therapeutic Values: Normal –  Male: < 4 ng/mL  Female: < 0.5 ng/mL Collection:  Serum Separator Tube   What would cause increased levels? Increased: Benign Prostatic Hypertrophy (BPH) Prostate cancer Prostatitis Urinary retention   What would cause decreased levels? Decreased: Long-term use of NSAIDs- explained in part by the anti-inflammatory effect of these medications Thiazides- reduces bioavailable testosterone, associated with resulting in functional hypogonadism Statins- cholesterol plays a role in synthesis of androgen, which affects the size of the prostate 5-alpha-reductase inhibitors- due to the effect on prostate size.

Thiazides are recommended first line agents for the treatment of hypertension.  They have been demonstrated to lower cardiovascular disease.  Which thiazide to choose has been a long-standing issue. In this interview, Areef Ishani MD, MS and W. Douglas Weaver MD, MACC discuss AHA Late-Breaker: DCP – Chlorthalidone Compared to Hydrochlorothiazide for the Prevention of Cardiovascular Events in Patients with Hypertension. Subscribe on Apple Podcasts | Subscribe on Google Play | Subscribe to ACCEL

Thiazide diuretics have been in clinical use for more than 60 years. Small studies published in the 1950s/60s reported that chlorothiazide had less diuretic and antihypertensive effect in patients with lower glomerular filtration rates which led to the belief that thiazides are ineffective in advanced CKD.  The Chlorthalidone in Chronic Kidney Disease (CLICK) Trial challenges this dogma. Guest Authors: Michael Ernst, PharmD, BCGP and Michelle A. Fravel, PharmD, BCPS Music by Good Talk

Loops, Thiazides, Potassium-sparing, and Osmotic Diuretics

Hello everyone! Welcome to the WPB Health Consulting Podcast. Where we bring clarity to coaching. In 2017, the mission to bring clarity to evidence-based health coaching was created. WPB Health Consulting's mission is to bring clarity to coaching and consulting practice. WPB stands for Wellness, Performance, and Bodybuilding. How is by developing and elevating health coaches and clients education and practical application. This is done by our coaching service and podcast! Our coaching service: Will empower you and be in constant contact to uplift you toward your goals. Our podcast: Will provide FREE evidence-based coaches in all areas of life. By doing so, coaches and clients will bring clarity on how to communicate and elevate their health habits through evidence-based practice. The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images and information, contained on or available through this website is for general information purposes only. WPB Health Consulting makes no representation and assumes no responsibility for the accuracy of the information contained on or available through this website, and such information is subject to change without notice. You are encouraged to confirm any information obtained from or through this website with other sources and review all information regarding any medical condition or treatment with your physician. NEVER DISREGARD PROFESSIONAL MEDICAL ADVICE OR DELAY SEEKING MEDICAL TREATMENT BECAUSE OF SOMETHING YOU HAVE READ ON OR ACCESSED THROUGH THIS WEBSITE. On Today's podcast: 1. Dominic Kuza's journey with competitors this year. 2. Common themes of diuretic use you are seeing within the competition community 3. Defining Diuretics and their mechanism of action: The three types of diuretic medications are called thiazide, loop, and potassium-sparing diuretics. All of them make your body excrete more fluids via urine. Understanding Thiazide diuretics: Thiazides are the most commonly prescribed diuretics. They're most often used to treat high blood pressure. These drugs not only decrease fluids, they also cause your blood vessels to relax. 4. Thiazides are sometimes taken with other medications used to lower blood pressure. Examples of thiazides include: chlorthalidone Hydrochlorothiazide (Microzide) metolazone indapamide 5. Understanding Loop diuretics Loop diuretics are often used to treat heart failure. Examples of these drugs include: torsemide (Demadex) furosemide (Lasix) bumetanide Bumex 6. Potassium-sparing diuretics Potassium-sparing diuretics reduce fluid levels in your body without causing you to lose potassium, an important nutrient. The other types of diuretics cause you to lose potassium, which can lead to health problems such as arrhythmia. Potassium-sparing diuretics may be prescribed for people at risk of low potassium levels, such as those who take other medications that deplete potassium. Potassium-sparing diuretics don't reduce blood pressure as well as the other types of diuretics do. Therefore, your doctor may prescribe a potassium-sparing diuretic with another medication that also lowers blood pressure. Examples of potassium-sparing diuretics include: Amiloride Triamterene (Dyrenium) Spironolactone (Aldactone) Eplerenone (Inspra) 7. Discussing the dangers of nutrition and monitoring potassium intake with diuretic use 8. Discuss the effects of the longevity of bodybuilding and diuretic use

Patients with G6PD deficiency who are taking probenecid are at increased risk for hemolytic anemia. In a patient taking probenecid, they need to have adequate kidney function for the drug to work. GI upset is likely the most common adverse effect of probenecid. It can be given with food. Probenecid can raise the concentrations of many common antibiotics like penicillins and cephalosporins. Remember that there are many medications that can oppose the beneficial effects of probenecid. Thiazides, niacin, and some immunosuppressants can raise uric acid.

Thiazides | NCC | PTH | Ca++ Reabsorption --- Support this podcast: https://anchor.fm/kamesa-anota/support

Solve hypernatremia with tips and tactics from Dr. Joel Topf, MD (@kidney_boy), our Kashlak Chief of Nephrology. We review the diagnostic workup for hypernatremia, polydipsia and polyuria, review the pathophysiology of diabetes insipidus, and how to differentiate between nephrogenic and central DI. Plus, we walk through how to treat hypernatremia in the acute setting and Dr. Topf shares clinical pearls on why hypernatremia is the opposite of hyponatremia… It’s easy! Full show notes at https://thecurbsiders.com/episode-list. Join our mailing list and receive a PDF copy of our show notes every Monday. Rate us on iTunes, recommend a guest or topic and give feedback at thecurbsiders@gmail.com. Credits Written by Hannah R. Abrams and Joel Topf MD Producer: Hannah R. Abrams Cover Art and infographic by: Hannah R. Abrams Hosts: Hannah R. Abrams; Stuart Brigham MD; Matthew Watto MD, FACP Editors: Matthew Watto MD, FACP; Emi Okamoto MD  Guest: Joel Topf MD Check out Dr. Topf’s podcast! The NephJC podcast, Freely Filtered, discusses the latest NephJC topic every two weeks. Subscribe here or on iTunes.  Time Stamps 00:00 Intro, disclaimer, guest bio 03:25 Joel’s one liner and plug for his new podcast 05:34 Hannah shares a really weird analogy 07:10 Picks of the week*: In Shock (book) by Rana Awdish; HBO’s From the Earth to the Moon; Once Upon a Time in Hollywood (film); Glass(film) directed by M. Night Shyamalan (Stuart’s anti-pick)POCUS! Sign up for a course today from the ACP, AIUM or TRUST.  13:18 Why hypernatremia is easy 14:49 The case of Paula Uric - new onset hypernatremia with hypercalcemia 16:12 Hypernatremia risk factors; ADH, osmolality and the kidney  21:20 Loop of Henle and the sodium, potassium and 2 chloride channel 22:05 How hypercalcemia mimics nephrogenic diabetes insipidus 29:30 Hypercalcemia workup 33:10 Differentiating central from nephrogenic diabetes insipidus 37:35 DDAVP, desmopressin and treatment of nocturia 38:50 The case of Manny Uric - altered mental status and hypernatremia Na = 162; Why do patients in the ICU develop hypernatremia? 42:29 Calculate the fluid deficit; total body water 48:05 Estimate insensible losses (electrolyte free water clearance) 54:48 What if your hypernatremic patient is also hypovolemic? 57:30 Does fluid restriction work in heart failure? 58:35 Hypernatremia - Is there such a thing as too fast in adults?  63:44 Thiazides versus acetazolamide for nephrogenic DI 68:34 Take home points 71:20 Outro Links* In Shock (book) by Rana Awdish HBO’s From the Earth to the Moon Once Upon a Time in Hollywood (film) Glass (film) directed by M. Night Shyamalan (though consider avoiding, per Stuart) POCUS! Sign up for a course today from the ACP, AIUM or TRUST *The Curbsiders participates in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising commissions by linking to Amazon. Simply put, if you click on my Amazon.com links and buy something we earn a (very) small commission, yet you don’t pay any extra. Disclosures Dr Topf lists the following disclosures on his website: “I have an ownership stake in a few Davita run dialysis clinics and a vascular access center. Takeda Oncology made a donation to MM4MM the program that is taking me to Mount Everest in 2018”. The Curbsiders report no relevant financial disclosures. Citation Topf J, Abrams HR, Brigham SK, Okamoto E, Watto MF. “170 Hypernatremia is Easy with Joel Topf MD”. The Curbsiders Internal Medicine Podcast. https://thecurbsiders.com/episode-list. September 2, 2019.

Listen to our first ever discussion with @kidney_boy, Joel Topf MD. It’s a classic episode with a fresh intro as we prepare for @NephMadness 2019 with our friends from Twitter and @AJKDonline Dominate leg cramps, diuretic therapy, and resistant hypertension with tips from @kidney_boy, Joel Topf MD @kidney_boy, Chief of Nephrology Kashlak Memorial Hospital, co-creator @NephMadness. We start with basic renal physiology and build up to the treatment of resistant hypertension. Corrections: Dr Topf posted the following corrections on his blog PBfluids.com 3/22/2017 “I enjoyed the experience immensely, but in an hour of talking off the cuff I made some embarrassing mistakes: In describing water reabsorption I said it occured in the cortical collecting duct rather than the medullary collecting duct. In describing my cure for cramps I tell the story of Gitelman’s and say it is like congenital loop diuretics rather than congenital thiazide diuretics I mucked up the story about the MRFIT story and how it allowed a head to head comparison of HCTZ and chlorthalidone. I really oversold what happened.”   Full show notes at https://thecurbsiders.com/podcast. Join our newsletter mailing list. Rate us on iTunes, recommend a guest or topic and give feedback at thecurbsiders@gmail.com. Credits Written by: Matthew Watto MD Produced by: Stuart Brigham MD and Matthew Watto MD Cohosts: Stuart Brigham MD and Matthew Watto MD Guest: Joel Topf MD Sponsor Get your ACP membership today and use the code CURB100 to save $100 when you join by March 31, 2019. Time Stamps 00:00 Sponsor - Become a member of the American College of Physicians 00:28 Disclaimer, Intro, Recap of upcoming shows, Corrections and Omissions 05:50 Guest one-liner, Discussion of social media in medical education, Joel’s book 12:45 Twitter for medical education including NephJC and NephMadness 19:50 Sponsor - Become a member of the American College of Physicians 21:30 Intro to diuretics, mechanism of action and a brief review of renal physiology 28:26 Use of thiazide diuretics 30:18 Chlorthalidone versus hydrochlorothiazide 34:47 Diuretics and hyponatremia, Monitoring electrolytes and renal function on diuretics 39:05 Leg (muscle) cramps and pickle juice 42:55 Thiazides, osteoporosis and fracture prevention 45:32 Resistant hypertension and  the workup for secondary hypertension 53:36 Loop diuretics: how to choose an agent, dosing 62:15 Take home points 67:00 Outro

Thiazide diuretics are well-known to help with edema and hypertension. Thiazides need to monitored for electrolyte imbalances. Hypokalemia is a real and significant possibility. Thiazide diuretics can also raise uric acid which can impact our patients with gout. Pay attention to use in this patient population. I also cover drug interactions and the mechanism of action of thiazide diuretics on this episode. Enjoy the show!

Commentary by Dr. Valentin Fuster

Tina revisits ACEI, ARB, BB, and Thiazides, which were covered previously with the hypertension episodes, and introduces a few new medications as well: Mineralocorticoid Receptor Antagonists: spironolactone and eplerenone Loop diuretic: furosemide Digoxin Vasodilators: hydralazine and isosorbite dinitrate For a quick summary of the CCS 2013 recommendations: ACE inhibitors: all asymptomatic patients with an EF […] The post CHF 2: medications appeared first on Family Pharm Podcast.

We reviewed some evidence on the treatment of hypertension that are contradictory to the CHEP 2013 guidelines summarized in our previous episodes. Salt restriction for hypertension CHEP 2013: 1500 mg of sodium per day is recommended for adults age 50 years or less; 1300 mg per day if age 51 to 70 years; and 1200 mg […] The post Hypertension 4: EBM Special appeared first on Family Pharm Podcast.