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A tiny molecule produced inside your body may play a major role in how well you circulate blood, manage inflammation, exercise, and age. In this episode of Sharkpreneur, Seth Greene interviews Nathan S. Bryan, Ph.D., Founder, Chairman, and CEO of Bryan Therapeutics, Inc., who explains nitric oxide's role in blood-vessel function, tissue oxygenation, inflammation, metabolism, and cellular energy, and shares his view on everyday habits that can affect the body's natural production. He also discusses the oral microbiome, dietary considerations, lifestyle practices, consumer education, and the research-based standards he believes people should use when evaluating nitric oxide-related products. Key Takeaways:→ Nitric oxide helps regulate blood flow, oxygen delivery, inflammation, metabolism, and cellular signaling. → Oral-care habits may affect the oral microbiome, which helps metabolize dietary nitrate.→ Green vegetables and beets may contain dietary nitrate.→ Product claims should be supported by scientific and clinical data. → Lifestyle habits influence nitric oxide production. Dr. Nathan S. Bryan earned his undergraduate Bachelor of Science degree in Biochemistry from the University of Texas at Austin and his doctoral degree from Louisiana State University School of Medicine in Shreveport, where he was the recipient of the Dean's Award for Excellence in Research. He pursued his postdoctoral training as a Kirschstein Fellow at Boston University School of Medicine's Whitaker Cardiovascular Institute. After a two-year post-doctoral fellowship, in 2006, Dr. Bryan was recruited to join the faculty at the University of Texas Health Science Center at Houston by Ferid Murad, M.D., Ph.D., 1998 Nobel Laureate in Medicine or Physiology. Dr. Bryan has been involved in nitric oxide research for the past 25 years and has made many seminal discoveries in the field, has dozens of issued patents, and has published more than 100 peer-reviewed scientific articles in some of the top science and medical journals. Dr. Bryan is a best-selling author and successful entrepreneur who has built a billion-dollar enterprise value portfolio of companies. Dr. Bryan is one of the most successful inventors and top revenue producers in the history of the University of Texas Health Sciences Center at Houston. He is currently the Founder, Chairman, and CEO of Bryan Therapeutics, Inc., a privately held, clinical-stage biotechnology company actively engaged in the discovery and development of nitric oxide-based therapies. BTI has active drug development programs in heart disease, Alzheimers' Disease, and topical drugs for diabetic ulcers and non-healing wounds. Dr. Bryan's consumer line of nitric oxide products is among the most innovative and successful on the market. Dr. Bryan is an international leader in molecular medicine and nitric oxide biochemistry. Connect With Nathan:Website: https://n1o1.com/https://bryantherapeutics.com/ Instagram: https://www.instagram.com/drnathansbryan X: https://x.com/drnitric LinkedIn: https://www.linkedin.com/in/drnathansbryan/ YouTube: https://www.youtube.com/@drnathansbryannitricoxide
On this episode of Vitality Radio, Jared explores why your oral microbiome may be one of the most overlooked foundations of whole-body health. He explains how an imbalance in the bacteria living in your mouth can influence your teeth, gums, gut, sinuses, cardiovascular system, and more. Learn why simply killing germs isn't always the answer, how biofilms contribute to ongoing dental problems, and why supporting a healthy oral ecosystem may be a better long-term strategy. Jared also shares his personal oral care routine, discusses the connection between the oral and gut microbiomes, reviews the latest research on oral probiotics, and outlines a practical protocol using clean oral care products, targeted probiotics, and lifestyle strategies to help support healthy teeth, gums, fresh breath, and overall wellness. Products Discussed - Buy 3 more products from the collection for 20% off automatically in your cart for 30 days from show air date: https://vitalitynutrition.com/collections/oral-microbiome-support Additional Information:539: Your Mouth Might Be Making You Sick631: Clean Oral Care: What Really Belongs in Your Toothpaste? with Bruce Weyman636: Herbal Secrets: Neem - The “Terrain Shifter” for Gut, Skin & Microbiome HealthVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/
This week, Dr. Kahn discusses the FDA approval of the first oral PCSK9 inhibitor, Lipfendra (enclicitide), taken as a 20 mg daily tablet. In a study of nearly 3,000 patients with elevated LDL cholesterol despite treatment with statins and, in many cases, ezetimibe, LDL-C dropped by more than 50% while Lipoprotein(a) levels fell by 28%, with an excellent safety profile. The medication is expected to retail for approximately $315 per month and will be available in pharmacies soon. A larger outcomes trial evaluating its impact on heart attack and stroke rates is currently underway. Other topics include oatmeal for diabetes, avocados for cholesterol, ketogenic diets and cancer, serotonin and heart valve disease, air pollution and cardiovascular events, and the relationship between sweetened beverages, fruit juice, and high blood pressure. Dr. Kahn also mentions the air filtration system he uses at home and in his office, available at: airdoctorpro.com Finally, thanks to this week's sponsor, the Fresh Pressed Olive Oil Club. Learn more at getfreshDrKahn.com.
Questions to Ministers Hon MARAMA DAVIDSON to the Prime Minister: E tautoko ana ia i nga korero me nga mahi katoa a tona Kawanatanga? Does he stand by all of his Government's statements and actions? Rt Hon CHRIS HIPKINS to the Prime Minister: Does he stand by all his Government's statements and actions? NANCY LU to the Minister of Finance: What recent reports has she seen on the economy? Hon BARBARA EDMONDS to the Minister of Finance: Does she stand by all her statements and actions? RAWIRI WAITITI to the Prime Minister: Does he stand by all his Government's statements and actions? Dr DAVID WILSON to the Minister for Resources: What reports, if any, has he received on the Government's minerals strategy? Hon Dr AYESHA VERRALL to the Minister of Health: Does he stand by his statement that this Government is "Keeping GP visit costs the same for patients as last year"; if so, is it correct that current fees are the highest they've been in 20 years? CATHERINE WEDD to the Minister responsible for RMA Reform: What recent reports has he seen on the Government's reform of the New Zealand planning system? CHLÖE SWARBRICK to the Prime Minister: E tautoko ana ia i nga korero me nga mahi katoa a tona Kawanatanga? Does he stand by all of his Government's statements and actions? MILES ANDERSON to the Minister for Trade and Investment: What recent reports has he seen on enhancing New Zealand's international trade? ARENA WILLIAMS to the Minister of Commerce and Consumer Affairs: Does he stand by the Government's decision to abolish the role of Grocery Commissioner? TOM RUTHERFORD to the Minister of Commerce and Consumer Affairs: What actions is he taking to strengthen New Zealand's capital markets and support economic growth?
How up-to-date are you with your dentist visits? Oral diseases are among the most common and costly health issues affecting Australians and the healthcare system.
Vrae word geopper oor die frekwensie en koste van amptelike reise wat deur die land se topleierskap onderneem word. President Netumbo Nandi-Ndaitwah en haar man het 'n reeks plaaslike en internasionale werk- en staatsbesoeke onderneem, insluitend reise na Angola, Ghana, Tanzanië en China, tesame met streeksverbintenisse. Visepresident Lucia Witbooi en premier Elijah Ngurare het ook verskeie amptelike missies tuis en in die buiteland as deel van regeringsaktiwiteite gelei en bygewoon. IPC-president Panduleni Itula bevraagteken die relevansie van sulke reise.
La Audiencia Provincial de Madrid ha confirmado que Begoña Gómez se sentará en el banquillo. Se mantiene la acusación por **tráfico de influencias** y **malversación de caudales públicos**, mientras que se archivan los delitos de corrupción en los negocios y apropiación indebida por falta de tipicidad. Hosted on Acast. See acast.com/privacy for more information.
In this episode, we'll work on building strong language structures that will help you confidently create your own sentences. And using the hints provided you'll practice creating your own sentences, in Hindi like – ‘It will take me few more months to learn Hindi well.' and ‘Why will it take you longer to complete this work?' Kindly support us & get access to the transcript of this podcast as well as the detailed worksheet based on this podcast with more vocabulary and weekly Exercise worksheets on Patreon : https://www.patreon.com/learnhindionthego To take a free trial for online Hindi lessons visit: https://learnhindischool.com Find out more at https://learn-hindi-on-the-go.pinecast.co This podcast is powered by Pinecast.
Tanya 4 av Cap 1 Parte 2 -O estudo da Torá oral,fortalece a fé,amor e temor a Dus
In this episode of Dental Unfiltered, we sit down with Dr. Julia L. Jackson to dive deep into implant dentistry, oral surgery, and the critical business decisions every practice owner faces.We discuss why general dentists need to elevate their implant techniques and shift to a "prosthetically driven" mindset rather than focusing solely on clinical execution. Plus, Dr. Jackson shares invaluable insights on how to build a highly successful practice with a clear, profitable exit strategy in mind from day one.What We Cover:Prosthetically Driven Implantology: Shifting your mindset to improve patient outcomes and restorative success.Elevating the General Dentist: Mastering oral surgery and advanced implant techniques in a GP setting.The Business of Endings: Key strategies for structuring your practice with a lucrative exit plan.
Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we explore the latest advancements shaping the future of drug discovery and patient care. Veradermics is making significant strides with its oral minoxidil formulation aimed at addressing female pattern hair loss. The mid-stage clinical trial results have analysts optimistic about Veradermics' potential to capture a significant portion of this underserved market. The oral form of minoxidil, traditionally used in topical Rogaine products, offers a novel delivery method that could enhance patient adherence and improve outcomes, marking an innovative leap in dermatological treatments. Johnson & Johnson is navigating the expiration of Stelara's patent protection with resilience, as Tremfya steps up to fill the revenue gap. With quarterly sales exceeding $2 billion, Tremfya underscores the critical role of strategic lifecycle management and robust product pipelines in weathering patent cliffs. This success highlights the necessity for pharmaceutical companies to sustain growth through a well-rounded portfolio that can absorb such impacts. In oncology, Celcuity has achieved a pivotal milestone with FDA approval for its small molecule inhibitor targeting breast cancer. This therapy promises blockbuster potential and could become a new standard-of-care, expanding treatment options for patients. The approval reflects ongoing innovation in oncology, where small molecules continue to play an essential role alongside biologics in advancing cancer therapies. AI-driven drug discovery is gaining traction as Insilico Medicine partners with CDMO Bora in a potentially $2.5 billion deal. This collaboration underscores AI's transformative potential in accelerating drug discovery and development processes. By leveraging artificial intelligence, Insilico aims to identify new drug candidates more efficiently, expediting their journey from bench to bedside. Kelun-Biotech is marking significant progress with its SAC-TMT program targeting non-small cell lung cancer (NSCLC), filling gaps left by Merck's phase 3 efforts. This development is crucial for providing more tailored therapeutic options in oncology, illustrating how advancements in drug development are driving forward personalized medicine. Roche continues its exploration of Alzheimer's disease treatments with a multifaceted approach that includes both amyloid and tau proteins as targets. While its phase 3 amyloid program is prominent, Roche's interest in tau protein highlights the complexity of tackling neurological disorders and the need for diverse therapeutic strategies. Meanwhile, Biogen remains steadfast in defending its anti-tau Alzheimer's candidate following mixed phase 2 results that showed slowed cognitive decline. Despite stock volatility, this endeavor illustrates the high-stakes nature of Alzheimer's research as companies pursue novel approaches to this challenging disease. Regulatory landscapes are also shifting as Johnson & Johnson halts development of an eye disease gene therapy after disappointing phase 2b results. This move reflects the inherent risks involved in gene therapy and underscores the necessity for thorough evaluation at each clinical stage. Medtronic's recall of its Harmony delivery catheter system due to potential detachment risks serves as a reminder of the paramount importance of safety and quality control in medical device manufacturing. Such recalls impact patient safety and emphasize regulatory vigilance over device reliability. In summary, these innovations demonstrate the dynamic nature of the pharma and biotech industries where cutting-edge science drives progress. Integrating AI into drug discovery, managing product lifecycles post-patent expiry, advancing personalized medicine, and maintaining regulatory diligence collectively shape a landscape focused on improving patient outcomes worldwide. Turning to recent scientific developments: Eli Lilly's presentation at AAIC 2026 on their anti-amyloid Alzheimer's drug Kisunla explores maintenance therapy possibilities once amyloid levels fall below a threshold. This potential shift could signify a paradigm change by extending therapeutic benefits and possibly improving long-term outcomes for patients with Alzheimer's. Biogen's advances with its anti-tau Alzheimer's therapy partnered with Ionis Pharmaceuticals further validate the tau hypothesis. The promising mid-stage data on their antisense drug Diranersen opens opportunities for other companies like Denali Therapeutics to explore similar avenues for treating neurodegenerative diseases. The industry is also witnessing a resurgence in biotech IPOs during 2026's first half, recovering from a sluggish 2025. This surge signals investor confidence in biotechnological innovation while providing capital for advancing research pipelines. Financial activities within the sector are robust as Attovia Therapeutics files for an IPO to fund its competitive pipeline against Sanofi's Dupixent. Meanwhile, Advancell's $315 million Series D funding supports advancing prostate cancer candidates into Phase 3 trials, backed by big pharma confidence in radiotherapy's potential. Lastly, regulatory transparency improves as the FDA resumes releasing drug rejection letters after a temporary pause—a move likely to influence future submissions significantly by offering clearer guidance on regulatory expectations. These developments collectively highlight how scientific innovation and strategic maneuvers transform pharmaceutical landscapes, promising profound impacts on patient care through advanced therapies and novel treatments worldwide. As these trends unfold, they reflect an industry increasingly reliant on technological integration and collaborations to drive future growth and innovation.Support the show
Margaret finished telling you about labor and class struggle in Ancient Egypt Sources: https://historyrise.com/article/slavery-and-forced-labor-and-comparative-history-across-egypt/ https://www.touregypt.net/featurestories/slaves.htm https://www.touregypt.net/featurestories/medina.htm https://www.ancient-egypt-online.com/ancient-egypt-kingdoms.html https://vintage.tn/why-is-there-a-city-named-thebes-in-greece-and-a/ https://spokenpast.com/articles/egyptian-dream-book/ https://ancientegypt.fandom.com/wiki/Papyrus_Chester_Beatty_3 https://www.ancient-origins.net/myths-legends/egyptian-dream-book-001621 https://www.touregypt.net/kingtomb.htm https://blogs.nature.com/houseofwisdom/2013/01/voluntary-slavery-ancient-egyptians-paid-a-monthly-fee-to-become-temple-slaves.html https://www.theguardian.com/world/2010/jan/11/great-pyramid-tombs-slaves-egypt https://www.thecollector.com/hatshepsut-egyptian-queen-king/ https://en.wikipedia.org/wiki/Nitocris https://historicaleve.com/how-many-cleopatras-were-there-in-egypt/ https://www.thecollector.com/interview-queen-cleopatra-with-prof-paul-cartledge-oxford/ https://www.workingnowandthen.com/blog/wage-theft-the-50-billion-crime-against-workers/ https://www.thecollector.com/how-ancient-egyptians-lived-and-worked-in-the-valley-of-kings/ https://www.google.be/books/edition/Brotherhood_of_Kings/JTvRCwAAQBAJ?hl=fr&gbpv=1&dq=chiefs+of+punt&pg=PA143&printsec=frontcover https://www.wonderfulmuseums.com/museum/why-does-the-british-museum-not-return-artifacts/ https://www.history.com/articles/what-is-the-rosetta-stone Oral correspondence https://www.history.com/articles/mummy-unwrapping-parties-egyptomania https://editions.covecollective.org/content/egypt-and-orientalism https://everydayorientalism.wordpress.com/2023/08/11/orientalism-through-time-and-place-a-virtual-exhibit/ https://ninercommons.charlotte.edu/record/2825?v=pdf https://www.worldhistory.org/article/1089/the-first-labor-strike-in-history/See omnystudio.com/listener for privacy information.
Highlights from the PER® CME activity "Oncology Town Hall: Updates From Chicago: Oral SERDs in HR+/HER2− Metastatic Breast Cancer–What the Latest Data Really Tell Us" — this podcast is not certified for credit. To participate in the full accredited activity and earn CME credit, use the link below.In this podcast, experts Virginia Kaklamani, MD, DSc; Kamel Abou Hussein, MD; Javier Cortés, MD, PhD; and Seth A. Wander, MD, PhD, discuss American Society of Clinical Oncology (ASCO) 2026 updates about data for oral selective estrogen receptor degraders (SERDs) to treat metastatic, HR-positive breast cancer.Earn CME credit by completing the full accredited activity (available through June 29, 2027): https://www.gotoper.com/courses/oncology-town-hall-updates-from-chicago-oral-serds-in-hrher2-metastatic-breast-cancerwhat-the-latest-data-really-tell-us This podcast, including the narration, was developed by PER® (Physicians' Education Resource®, LLC) editorial staff from the full online CME activity developed with these faculty. The narration was voiced by a PER staff member or by an AI tool. The podcast contains no product advertising. The full activity is supported by an educational grant from Stemline Therapeutics, Inc.This content is for educational purposes only and is not a substitute for the independent clinical judgment of a health care professional. Faculty may discuss investigational or off-label uses; consult prescribing information for any products discussed.
Primary author Ayesha Siddiqui joins podcast hosts Hannes Prescher and Idorenyin "Edy" Ndem in a discussion about phenotypic heterogeneity of cleft lip and palate, and sociodemographic factors that affect care of patients in Pakistan. Read the article here.
Don't have time to listen to the entire Dave & Chuck the Freak podcast? Check out some of the tastiest bits of the day, including a Russian man gets his penis bit off and why surprise oral isn't always a great thing, the show argues bagels plus much more!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Highlights from the PER® CME activity "Cases and Conversations: Optimizing Oral SERD-Based Therapy After CDK4/6 Inhibition in HR+/HER2– MBC" — this podcast is not certified for credit. To participate in the full accredited activity and earn CME credit, use the link below.In this podcast, experts Virginia Kaklamani, MD, DSc; Antonio Giordano, MD, PhD; Nadia Harbeck, MD, PhD; and Sarah Sammons, MD, discuss the use of oral SERD-based therapy in the treatment of HR+/HER2– metastatic breast cancer through a series of clinical cases. Earn CME credit by completing the full accredited activity (available through June 30, 2027): https://www.gotoper.com/courses/cases-and-conversations-optimizing-oral-serd-based-therapy-after-cdk46-inhibition-in-hrher2-mbc-xv6m This podcast, including the narration, was developed by PER® (Physicians' Education Resource®, LLC) editorial staff from the full online CME activity developed with these faculty. The narration was voiced by a PER staff member or by an AI tool. The podcast contains no product advertising. The full activity is supported by an educational grant from Stemline Therapeutics, Inc.This content is for educational purposes only and is not a substitute for the independent clinical judgment of a health care professional. Faculty may discuss investigational or off-label uses; consult prescribing information for any products discussed.
Where science meets the sulcus—bridging microbiology, diagnostics, and modern hygiene care for systemic healing. Resources: @oralhealthactivist on Instagram Camille Zenobia on Linked In
Margaret talks to you about labor and class struggle in Ancient Egypt. Sources: https://historyrise.com/article/slavery-and-forced-labor-and-comparative-history-across-egypt/ https://www.touregypt.net/featurestories/slaves.htm https://www.touregypt.net/featurestories/medina.htm https://www.ancient-egypt-online.com/ancient-egypt-kingdoms.html https://vintage.tn/why-is-there-a-city-named-thebes-in-greece-and-a/ https://spokenpast.com/articles/egyptian-dream-book/ https://ancientegypt.fandom.com/wiki/Papyrus_Chester_Beatty_3 https://www.ancient-origins.net/myths-legends/egyptian-dream-book-001621 https://www.touregypt.net/kingtomb.htm https://blogs.nature.com/houseofwisdom/2013/01/voluntary-slavery-ancient-egyptians-paid-a-monthly-fee-to-become-temple-slaves.html https://www.theguardian.com/world/2010/jan/11/great-pyramid-tombs-slaves-egypt https://www.thecollector.com/hatshepsut-egyptian-queen-king/ https://en.wikipedia.org/wiki/Nitocris https://historicaleve.com/how-many-cleopatras-were-there-in-egypt/ https://www.thecollector.com/interview-queen-cleopatra-with-prof-paul-cartledge-oxford/ https://www.workingnowandthen.com/blog/wage-theft-the-50-billion-crime-against-workers/ https://www.thecollector.com/how-ancient-egyptians-lived-and-worked-in-the-valley-of-kings/ https://www.google.be/books/edition/Brotherhood_of_Kings/JTvRCwAAQBAJ?hl=fr&gbpv=1&dq=chiefs+of+punt&pg=PA143&printsec=frontcover https://www.wonderfulmuseums.com/museum/why-does-the-british-museum-not-return-artifacts/ https://www.history.com/articles/what-is-the-rosetta-stone Oral correspondence https://www.history.com/articles/mummy-unwrapping-parties-egyptomania https://editions.covecollective.org/content/egypt-and-orientalism https://everydayorientalism.wordpress.com/2023/08/11/orientalism-through-time-and-place-a-virtual-exhibit/ https://ninercommons.charlotte.edu/record/2825?v=pdf https://www.worldhistory.org/article/1089/the-first-labor-strike-in-history/See omnystudio.com/listener for privacy information.
Stop approaching oral sex like a warmup routine and learn the exact mechanics used by professionals to deliver unforgettable results. Discover why mainstream adult videos depict completely wrong techniques and how to use Erik Everhard's trademark Cross-T technique to maximize clitoral stimulation.Master the five critical principles of face distance, stamina, psychological pacing, and rhythmic consistency to control her response and trigger intense cumulative arousal.VIDEOS TO WATCH NEXT:Watch this playlist to figure out how to fix your failing marriage: https://www.youtube.com/playlist?list=PLEXcvFDdRqPuu_G8-sTLS7eXT7myvidMFWatch this playlist to help you get over your ex for good: https://www.youtube.com/playlist?list=PLEXcvFDdRqPsZ9JCTSAIkin-oMnavqNJZWatch this playlist to develop an unshakable frame and take control of your life: https://youtube.com/playlist?list=PLEXcvFDdRqPvgN8idHfGfOp3gA8Y0tMxT&si=NccZ6koKYz3hSuUz--------------------------------------------FREE EBOOKS➡️ She's Made You Weak: https://ebook.fixdeadbedrooms.com➡️ Fine... Here's How You Get Her Back: https://ebook.getoveryourex.us➡️ The 4 Magic $3X Positions: https://sexytime.fixdeadbedrooms.com--------------------------------------------BOOKS AND WORKBOOKS➡️ Find all of my books here: https://mybook.to/comeonmanpod➡️ Find all of my workbooks here: https://mybook.to/RPWorkbooks--------------------------------------------FOLLOW MEFollow on TikTok - https://www.tiktok.com/@comeonmanpodFollow on Instagram - https://www.instagram.com/comeonmanpodcast/Follow on Facebook - https://www.facebook.com/comeonmanpodcastFollow on X - https://x.com/bestmenspodFollow on Gettr - https://gettr.com/user/comeonmanpodFollow on Truth - https://truthsocial.com/@comeonmanpodFollow on Substack - https://substack.com/@comeonmanpod--------------------------------------------COMMUNITIES➡️ Join The W.O.L.F. Pack: https://wolf.comeonmanpod.com/➡️ Become a Spotify Channel Subscriber: https://podcasters.spotify.com/pod/show/comeonman/subscribe--------------------------------------------
Unnecessary, a breach of the bill of rights, and morally indefensible - that's how the government's move on orders have been described at parliament today. But another submitter says the system currently has no teeth to deal with aggressive and non-compliant behaviour. Oral submissions are being made on the Summary Offences Amendment Bill. Political reporter Lillian Hanly has more.
CME in Minutes: Education in Rheumatology, Immunology, & Infectious Diseases
Please visit answersincme.com/BJN860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Rajesh Gandhi, MD. In this activity, an expert in infectious diseases discusses novel oral antiretroviral therapy (ART) for the management of human immunodeficiency virus (HIV). Upon completion of this activity, participants should be better able to: Recognize the rationale for novel oral ART regimens in the management of virologically suppressed HIV infection; Review the clinical impact of novel emerging oral ART regimens for patients with virologically suppressed HIV infection; and Formulate patient-centered strategies for optimizing the personalized management of oral ART for patients with virologically suppressed HIV infection.
Please visit answersincme.com/BJN860 to participate, download slides and supporting materials, complete the post test, and get a certificate. Presented by Rajesh Gandhi, MD. In this activity, an expert in infectious diseases discusses novel oral antiretroviral therapy (ART) for the management of human immunodeficiency virus (HIV). Upon completion of this activity, participants should be better able to: Recognize the rationale for novel oral ART regimens in the management of virologically suppressed HIV infection; Review the clinical impact of novel emerging oral ART regimens for patients with virologically suppressed HIV infection; and Formulate patient-centered strategies for optimizing the personalized management of oral ART for patients with virologically suppressed HIV infection.
INTRODUCING Behind the Knife OBGYN Oral Board Review!The oral boards aren't just about knowledge—they are about executing under pressure. This course is designed to give you the structure and confidence to command the room. We have curated 98 high-yield scenarios covering the "Big Three" of the exam: Obstetrics, Gynecology, and Office Practice. Whether it's a surgical emergency or a complex clinic workup, we will walk you through exactly how to articulate your plan, defend your decisions, and pass this exam.Each scenario includes 2 parts. The first part is a perfectly executed scenario. If you are able to achieve this level of performance in your preparation you are sure to pass the oral exam with flying colors. The second part introduces high-yield commentary to each scenario. This commentary includes tips and tricks to help you dominate the most challenging scenarios in addition to practical, easy-to-understand teaching that covers the most confusing topics. We are confident you will find this unique, dual format approach a highly effective way to prepare for the test.Please check out the preview episodes below that include Parts A and B, with and without commentary.This course includes access to our Oral Board Simulator. Step into the hot seat and experience the pressure of the real exam and receive detailed, actionable feedback with the most advanced oral board prep available. 3-Month Purchase - 10 exams 6-Month Purchase - 22 exams 12-Month Purchase - 46 exams Learn More: https://behindtheknife.org/premium/obgyn-oral-board-reviewDOMINATE THE DAY!
Your vagina has its own ecosystem, and no, that yeast on your test doesn't automatically mean infection. In this episode, The Cuntsultant breaks down the vaginal microbiome: why lactobacilli are your best friend, how your gut and hormones secretly run the show, and why "rebalance your pH" is basically meaningless advice. We get into recurrent BV, partner treatment, boric acid (plus the Poison Control call about oral sex timing), and why yogurt does NOT belong in your vagina. Honest, funny, shame-free.✨ Special Offers: ✨Splash Blanket! | Use code Jordan15ProDx Health | Use JordanDnelle to save 25%Thank you to our Sponsors: Splash Blanket, Prodx, PhexxJump to the Good Stuff:05:57 – Who is The Cuntsultant?07:55 – What is the vaginal microbiome and why it matters08:30 – The gut-hormone connection10:06 – Their Daye test results - shockingly low lactobacilli10:50 – Yeast/mycoplasma showing up on a test doesn't always mean infection16:41 – New guidance: BV treatment includes the partner20:27 – Tight clothes, diet, and other everyday microbiome disruptors29:25 – Why your vaginal pH shifts throughout your cycle32:52 – Boric acid 101 and the Poison Control call about oral sex timing37:36 – "Energetically bad semen" - the ex-partner BV theoryPleasure Highlights:Yeast or "weird" bacteria on a test ≠ infection. Oral probiotics can support vaginal health, but check strains. Your vaginal pH is supposed to shift throughout your cycle.Boric acid needs a 24-hour buffer before oral sex.Connect with The Cuntsultant:Instagram @thecvntsultantWebsite: TheCuntsultant.comEnhance your self-awareness by acknowledging and understanding your behavior patterns, and foster a deeper connection with your inner self. Get the Unleashing My Power: A Women's Empowerment and Gratitude Journal to reclaim your power through daily gratitude. Learn more HERE.Connect with Jordan D'Nelle:Facebook @jordandnelleInstagram @jordandnelleInstagram @TheVVVPodcastTikTok @jordandnelleYoutube @jordandnelleWebsite: Jordan D'NelleEmail: JordanDnelle@VaginasVulvasandVibrators.comLove this Episode? Join the Patreon: patreon.JordanDnelle.comLeave a review on iTunes.Subscribe & Follow on socials!Listen and Subscribe to the Podcast:Apple PodcastSpotify PodcastYoutube @jordandnelle*Disclaimer: This podcast is for informational and/or entertainment purposes only and is not a substitute for medical advice, diagnosis, or treatment. The views and opinions expressed are my own, or those of my guests, and do not necessarily reflect the views of any organizations or institutions with which I am affiliated.Vaginas, Vulvas, and Vibrators, the unapologetic women's sexual wellness podcast, normalizing pleasure, bodies, and sexual health through expert, shame-free conversations.PhexxINDICATIONPhexx® is an on-demand prescription birth control used to prevent pregnancy. Phexx is not effective when used after sex.IMPORTANT SAFETY INFORMATIONRare cases (0.36%) of bladder and kidney infection have been reported. If you have a history of urinary tract problems that keep coming back, you should not use Phexx.Contact your healthcare provider if you are experiencing genitourinary side effects such as vaginal burning, itching, discharge, genital discomfort (including in male partners), yeast infection, urinary tract infection or bacterial vaginosis.Phexx does not protect against any sexually transmitted infections, including HIV. Avoid using Phexx with a vaginal ring.Avoid Phexx if you or your sexual partner is allergic to lactic acid, citric acid, potassium bitartrate, or any of the Ingredients in Phexx. Stop using Phexx If you develop an allergic reaction.For more information about Phexx, talk to your healthcare provider and see full Product Informationat www.phexx.com.Please report side effects by contacting Evofem Biosciences® toll-free at 1-833-EVFMBIO or contact FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.EVFM-PHX-000068
Joff Lacey and Imogen Fecher-Jones interview six oral abstract finalists at this years' EBPOM. Nora Cruz Rodriguez; Association Between Participation in Remote Prehabilitation and High-Dependency Unit Length of Stay After Oesophagectomy and Radical Cystectomy: A Retrospective Cohort. Alexios Dosis; Remote wearable monitoring as a preoperative risk assessment tool. Ned Douglas; The Fluids, Atomoxetine or Midodrine (FAME) pilot trial. Tom Scodellaro; The new normal: CPET findings in patients aged 80 years and older. Gerry O'Callaghan; Preventing and Reducing Re-Presentations and Admissions following surgery, new thinking required. Sandy (Alexander) Jackson; Cost of Radial Arterial Line Placement in UK Operating Theatres. -- The 2026 International Practicum on Cardiopulmonary Exercise Testing will be held at the Balmer Lawn Hotel in Brockenhurst, UK, from September 16th to 18th this year. It is organised by iPOETTS , the international perioperative testing and training society. Come and join us at this premier educational event designed for clinicians, scientists, and healthcare professionals interested in sport, exercise, and perioperative medicine. This is an International Perioperative Testing and Training Society accredited event so when you attend you can get your iPOETTS accreditation, showing that you are a practitioner who has reached a high, standardized level of competence in performing and interpreting Cardiopulmonary Exercise Testing (CPET) for patients preparing for major surgery. Go now to http://www.ebpom.org
The episode explains how to use minoxidil for hair loss, emphasizing that it supports follicles and prolongs the anagen phase but does not block DHT (with topical dutasteride mentioned as a scalp-focused DHT option). It reviews evidence that 5% topical minoxidil is optimal (better than 2% and superior to 10%), works best on the crown/vertex, and should be applied to the scalp—not the hair—with expectations set for gradual results and possible early shedding. Twice-daily topical use is recommended unless combined with 0.01% tretinoin, which can make once-daily use similarly effective, though irritation can occur. Microneedling combined with minoxidil is strongly recommended based on a 2013 RCT, with guidance on depth (0.5–1.0 mm), frequency, and waiting 12–24 hours (or longer with tretinoin) before applying minoxidil. The episode also compares oral minoxidil dosing, notes a 2024 RCT showing similar outcomes to topical at 5 mg, and details systemic side effects, monitoring, and cautions including pet toxicity with topical use. Full Hair Loss Podcast — Wnt vs DHT https://www.youtube.com/watch?v=bswq-Qhfebs Minoxidil + Microneedling — 2013 Study https://pmc.ncbi.nlm.nih.gov/articles/PMC3746236/ 5% vs 2% Topical Minoxidil https://pubmed.ncbi.nlm.nih.gov/12196747/ 5% vs 10% Topical Minoxidil https://pubmed.ncbi.nlm.nih.gov/31403367/ Minoxidil + 0.01% Tretinoin Study https://pubmed.ncbi.nlm.nih.gov/17902730/ Oral vs Topical Minoxidil — 2024 Study https://pmc.ncbi.nlm.nih.gov/articles/PMC11007651/ Topical Dutasteride Study https://pmc.ncbi.nlm.nih.gov/articles/PMC12405733/ Topical Minoxidil Drug Information https://medlineplus.gov/druginfo/meds/a689003.html Oral Minoxidil Drug Information https://medlineplus.gov/druginfo/meds/a682608.html Tretinoin Drug Information https://medlineplus.gov/druginfo/meds/a682437.html Dutasteride Drug Information https://medlineplus.gov/druginfo/meds/a603001.html Minoxidil Toxicity in Dogs and Cats https://pubmed.ncbi.nlm.nih.gov/34370845/ Sildenafil / Viagra Drug Information https://medlineplus.gov/druginfo/meds/a699015.html Tadalafil / Cialis Drug Information https://medlineplus.gov/druginfo/meds/a604008.html Show Notes 00:00 Welcome to the Hart2Heart Podcast 00:45 Minoxidil Basics 01:43 DHT And What It Misses 03:07 How Minoxidil Works 03:55 Best Areas To Treat 04:30 Choosing The Right Strength 05:55 Once Or Twice Daily 08:28 Applying It Correctly 10:10 Microneedling Protocol 15:17 Formulations And Routine 18:14 Topical Side Effects 19:34 Shedding And Pet Safety 20:44 Oral Minoxidil Overview 22:53 Dosing And Risks 27:39 Combining Oral And Topical 28:36 Final Takeaways The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart
In this episode of A Tale of Two Hygienists, Jessica and Dave welcome Candi Kidd, RDH, BSDH, MEd, to discuss the unique challenges patients with special healthcare needs face when accessing oral healthcare. From medically complex and tube-fed patients to collaborating with caregivers and healthcare teams, Candi shares practical strategies for creating more inclusive, compassionate, and effective dental experiences. This conversation challenges clinicians to rethink accessibility, advocacy, and the future of patient-centered care. In this episode, we discuss: Common barriers to oral healthcare for patients with special healthcare needs Oral health considerations for medically complex and tube-fed patients Collaborating with caregivers and interdisciplinary healthcare teams Adapting preventive, therapeutic, and educational approaches Creating more inclusive and compassionate dental experiences The role of advocacy in improving access to care Practical strategies clinicians can implement immediately Where dental education and healthcare systems can continue to improve Connect with Candi Kidd: Email: candicea31@gmail.com Instagram: @the.sunnysister Connect with the Hosts: Jessica Atkinson: jatkinson@endeavorb2b.com Dave Torres: dtorres@endeavorb2b.com
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SXA865. CME/MOC/AAPA/IPCE credit will be available until June 15, 2027.Breaking Barriers in cUTI Care: Integrating Novel Oral Therapies and Transitions of Care In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis educational activity is supported by an independent medical education grant from GSK.Disclosure information is available at the beginning of the video presentation.
Recorded live at Bupa Dental Health Is Live, this Dental Leaders episode sees Payman joined by Andrew Bower from Philips Oral Healthcare for a sharp look at dentistry in 2040. The conversation moves from AI, robotics and connected toothbrushes to the bigger question of how oral health can become part of everyday whole-body care. Andrew explores Philips' long-term view on prevention, consumer behaviour, clinical evidence and the challenge of making oral care feel less like a chore and more like a daily ritual. There's also a grounded reminder that, even with smarter tools and faster data, dentistry still comes back to care, trust and human connection.In This Episode00:02:05 - Dentistry in 204000:04:15 - Predictions and connectivity00:05:00 - Oral care apathy00:08:00 - Power toothbrush adoption00:10:30 - Global dental differences00:12:20 - Mouth-body connection00:14:00 - Diagnostics and data00:15:35 - Robots and clinicians00:22:20 - Connected toothbrushes00:40:20 - AI and productivity00:47:25 - Last days and legacy00:48:00 - Fantasy dinner partyAbout Andrew BowerAndrew Bower is the global product category lead for Philips Oral Healthcare. With more than 20 years at Philips across consumer health, women's health and oral care, he brings a global view of how technology, prevention and behavioural change are shaping the future of healthcare.
In this episode, you will listen to a passage in Hindi and we will train you to comprehend it and respond to questions based on it. And through interactive quizzes, we'll help you learn how to say, in Hindi – the sentences like – ‘Does she often come here early?' and ‘He is punctual.' Kindly support us & get access to the transcript of this podcast as well as the detailed worksheet based on this podcast with more vocabulary and weekly Exercise worksheets on Patreon : https://www.patreon.com/learnhindionthego To take a free trial for online Hindi lessons visit: https://learnhindischool.com Find out more at https://learn-hindi-on-the-go.pinecast.co This podcast is powered by Pinecast.
Chris talks with Jonathan Geltner about the best (but still flawed) adaptation of The Hobbit. Get ready for...your greatest adventure! Among other things, we discuss: 1:32 — The 1977 NBC broadcast 2:31 — Childhood memories of the cartoon 5:48 — Rankin/Bass as directors 5:58 — Rankin's "no additions" philosophy 6:15 — Top Craft & the Studio Ghibli connection 7:39 — Music & the folk singer-songwriter style 8:11 — Critical reception & Hugo nomination 8:36 — What the adaptation kept vs. omitted 9:00 — Songs as background vs. foreground 12:10 — "Greatest Adventure" as anti-escapist message 20:01 — Fantasy's cultural status in the 1970s 21:59 — The Hobbit's cohesion vs. "episodic" label 25:57 — Bilbo's shifting narrative voice in Mirkwood 27:57 — Mirkwood: the weakest section 32:01 — Omitting Beorn & the Arkenstone's consequences 41:07 — Character designs: what works, what doesn't 46:54 — The Wood Elves' unusual look 51:59 — Star Wars, fantasy, and mainstream credibility 55:29 — Tolkien's "long ago in the quiet of the world" 1:00:53 — Oral storytelling tradition vs. film immersion 1:01:44 — One swap: what would you put back? 1:06:30 — Mental visualization & imaginative experience To read Jonathan's Substack, click here: https://jonathangeltner.substack.com/ To read my (far less illustrious) Substack, click here: https://pipkinsmiscellany.substack.com/ To buy Jonathan's first book, click here: https://slantbooks.org/books/absolute-music/ To email me, click inklingsvarietyhour@gmail.com
→ Watch on YouTube → Detailed Show Notes(00:00) A brief overview of these chapters.(05:08) Elijah calls down fire from heaven to consume King Ahaziah's soldiers that were sent to apprehend him.(12:02) Elisha is wrapped in the mantel of Elijah. Youth that mock Elisha are attacked by bears.(25:30) Possible reasons for Elijah being taken to heaven and translated.(26:29) Judah, Israel, and Edom join forces against Moab. They are in desperate need of water as they pass through the Negev desert. Jehoshaphat, king of Judah, directs his partners to the prophet Elisha who can provide the miracle they need.(30:08) The king of Edom, desperate to escape Judah, Israel, and Edom, sacrifices his own son to his god Chemosh. He is able to escape. This story emphasizes that monolatry existed in the ancient Near East.(33:27) Elisha multiplies the widow's oil. If we are willing to give what we have to God, he will give us back so much more.(38:07) Elisha raises the son of a widow woman from the dead. Prophets are types of Christ.(40:38) Naaman comes to Elisha to be healed of leprosy, but then second-guesses Elisha's instructions because they seemed too simple. One dip blessings compared to seven dip blessings. Faithfulness to God's commandments brings miracles.(48:12) Elisha refuses to accept a reward from Naaman for being healed. Gehazi secretly obtains the reward and is cursed with leprosy.(50:33) Naaman desires to take home some dirt from the place of his miraculous healing. Cultural context helps us understand why he would want to do this.(53:53) The sons of the prophets leave for more space. Elisha causes an ax to float.(56:44) Syria wages war against Israel in an effort to capture Elisha, their secret weapon. The Syrians are smitten with blindness and are led away in peace.(1:02:14) A seam in the text can be found in 2 Kings 6. Oral traditions that were written and later stitched together by editors leave evidence of their work. Israel, under siege by their enemy and experiencing a famine, is in need of a miracle. The Syrians leave their spoils behind and Elisha's promise of plentiful food is fulfilled.(1:08:40) Jezebel's death fulfills the earlier prophecy of Elijah. Time vindicates the prophets. → For more of Bryce Dunford’s podcast classes, click here. → Enroll in Institute → YouTube → Apple Podcasts → Spotify → Amazon Music → Facebook The post Ep 379 | 2 Kings 2-7, Come Follow Me 2026 (July 6-12) appeared first on Talking Scripture.
Pat Bond joined the Women's Army Corps in 1945, driven by patriotism and a desire to be among lesbians. The war required bodies, so the U.S. military turned a blind eye to service members' sexual orientation. But as Pat witnessed firsthand, once WWII was won, the anti-gay witch hunts began. Visit our episode webpage for background information, archival photos, and other resources, as well as a transcript of the episode. ——— Audio source: Oral history interview between Pat Bond and Allan Bérubé, September 30, 1990, World War II Project Papers (collection no. 1995-16), courtesy of the Gay, Lesbian, Bisexual, Transgender Historical Society. ———
I've worked for many years on my feet and had surgery on both knees. How much glucosamine should I take?Can you discuss oral vs. IV chelation? How do you determine which is appropriate?How important is nitric oxide, and how can I increase mine?Are there any supplements I should stop taking before getting blood tests?
The U.S. has decided not to renew a key trade agreement with Canada and Mexico. The decision plunges Minnesota's agriculture industry into uncertainty. Lawmakers grilled the Minnesota Department of Human Services' leader Wednesday about the agency's process for revalidating Medicaid providers. Oral arguments are set Thursday morning in three lawsuits challenging Minnesota's ban on prediction markets. In May, Minnesota became the first state to outlaw prediction markets, which allow users to bet on everything from sports to current events. Supporters of the ban say the markets are unregulated gambling platforms.
In this third episode of our four-part adolescent literacy miniseries, Susan Lambert, Ed.D., speaks with Jeanne Schopf, interventionist, national literacy consultant, and editor of the new book Reading Isn't Optional: Fulfilling the Promise of Literacy for Secondary Students. Susan and Jeanne discuss why belief systems about at-risk readers are often the biggest barrier to change, and why that's true at every level of a school system. They also explore how scheduling, data, and coaching serve as system-level levers that principals and teachers can use to transform secondary literacy outcomes—and why leadership remains the single most powerful lever of all.Show notes:Our Summer Learning Academy is underway! Reserve your spot now to join Susan Lambert for the next session and dive deeper into the latest reading comprehension research.Check out our Science of Reading resources for grades 6–8.Read Jeanne's book Reading Isn't Optional: Fulfilling the Promise of Literacy for Secondary Students.Check out Improving Adolescent Literacy: Effective Classroom and Intervention Practices.Read Providing Reading Interventions for Students in Grades 4–9.Listen to "Focused Implementation: Doing less to do more," with Doug Reeves, Ph.D.Get ready for Season 3 of the Amplify podcast Beyond My Years.Read Susan's NEW Science of Reading Substack.Join our community Faceook group.Connect with Susan Lambert. Quotes:"Everything rises and falls on leadership." —Jeanne Schopf"I had to learn that people don't care how much you know until they know how much you care." —Jeanne Schopf"If we really, truly want to change kids' lives and graduate readers, it's going to take all hands on deck. Everybody has to have a voice." —Jeanne Schopf"Success is a team sport." —Jeanne SchopfTimestamps*:0:00 Introduction What adolescent readers really need, with Jeanne Schopf3:00 Jeanne's journey from whole language to structured literacy7:00 Discovering structured literacy10:00 "We fall to the level of our systems"15:00 "Everything rises and falls on leadership."20:00 Belief systems and their impact on instruction and expectations22:00 Building intervention time into the secondary schedule26:00 What a good data meeting looks like30:00 Reading Isn't Optional as a call for action34:00 Inside the book: from belief to transformation42:00 Oral language and scaffolding grade-level text46:00 "You were never taught to read and it's not your fault"47:00 Closing thoughts*Timestamps are approximate
OA1274 - Can you sue if someone posts something nasty about you online? I mean maybe, but not like this. In today's episode, Lydia introduces us to the wild world of “Are We Dating the Same Guy?” and Jenessa walks us through a lawsuit that trips over its own feet while trying to take them down. It's a great opportunity to learn about some interesting Illinois laws against doxxing and your right to your likeness, and why the plaintiff failed miserably at mobilizing those laws in his favor. …Also, it wouldn't be a modern drama-filled lawsuit without attorneys using AI and failing to fact check. Tune in to hear a judge rage against the lying machine, and the lawyers that used it. D'Ambrosio v Meta Platforms, Inc., No. 25-2231 (7th Cir. 2026) Oral arguments Docket Permalink to Marc Trent's website Sanction laws: Fed. R. Civ. P. 11. Fed. R. Civ. P. 38. 28 U.S.C. § 1927 28 U.S.C. § 1912 Check out the OA Linktree for all the places to go and things to do!
Welcome to the latest Midlife Minute. Today, we're discussing how oral contraceptives and Depo Provera can impact women's bone health over time.Stay tuned as I walk you through the research, prescribing trends, and ways women can support their bone health. IN THIS EPISODE, YOU WILL LEARN: How peak bone mass in adolescence affects bone health later in life How oral contraceptives can interfere with the bone development of young women The lack of informed conversations about the bone health risks associated with long-term contraceptive use Why Depo Provera may have a stronger impact on bone density than oral contraceptives The importance of nutrition and strength training for supporting bone health How hormonal contraceptives can affect the gut microbiome and immune system What you need to consider regarding your bone density and long-term health if you've been using oral contraceptives or Depo for many years Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Resources: Depot medroxyprogesterone acetate, oral contraceptives and bone mineral density in a cohort of adolescent girls doi:10.1016/j.jadohealth.2004.07.005 Oral Contraceptive Use and Bone Density Change in Adolescent and Young Adult Women: A Prospective Study of Age, Hormone Dose, and Discontinuation doi:10.1210/jc.2010-3027 Adolescent use of combined hormonal contraception and peak bone mineral density accrual: A meta-analysis of international prospective controlled studies doi:10.1111/cen.13932 No need to specialize: reproductive health is for all adolescents doi:10.1016/j.jpag.2006.01.055 Injectable Hormone Contraception and Bone Density: Results from a Prospective Study doi:10.1097/00001648-200209000-00015 Hormonal contraception and the development of autoimmunity: A review of the literature doi:10.1080/00243639.2017.1360065 Oral contraceptives, reproductive factors and risk of inflammatory bowel disease doi:10.1136/gutjnl-2012-302362 Combined oral contraceptive use and the risk of systemic lupus erythematosus doi:10.1002/art.24398 Oral Contraceptives and Multiple Sclerosis/Clinically Isolated Syndrome Susceptibility doi:10.1371/journal.pone.0149094 The Experience of Surviving a High-Risk Pregnancy doi:10.1080/23293691.2016.1166104 Effects of 0.9 mg Recombinant Human Thyrotropin on Thyroid Size and Function in Normal Subjects: A Randomized, Double-Blind, Cross-Over Trial doi:10.1210/jc.2004-0914
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Naltrexone is often a first-line medication for AUD. It works as an opioid receptor antagonist, reducing the rewarding effects of alcohol and decreasing cravings. Patients frequently report that alcohol becomes less pleasurable while taking the medication. Oral naltrexone is typically dosed at 50 mg daily, while a long-acting injectable formulation is also available. Avoid use in patients taking opioids and use caution in significant liver dysfunction. Acamprosate helps maintain abstinence by modulating glutamate and GABA neurotransmission. Chronic alcohol use disrupts the balance between excitatory and inhibitory pathways in the brain, and acamprosate helps restore equilibrium. It is primarily eliminated renally, making it a useful option in patients with liver disease. The most common adverse effect is diarrhea. Disulfiram works through a completely different mechanism. It inhibits aldehyde dehydrogenase, causing acetaldehyde accumulation when alcohol is consumed. This can lead to flushing, nausea, vomiting, headache, and hypotension. Because of this aversive reaction, patient motivation and adherence are critical for success. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! Support The Podcast and Check Out These Amazing Resources! NAPLEX Study Materials BCPS Study Materials BCACP Study Materials BCGP Study Materials BCMTMS Study Materials Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated) Guide to Drug Food Interactions (Amazon Best Seller) Pharmacy Technician Study Guide by Meded101