Podcasts about Chronic kidney disease

In this episode, Dr. David Traster sits down with Dr. Michael Lebowitz, DC and Dr. Noah Lebowitz, DC of Supreme Nutrition Products to uncover what's really driving the chronic disease epidemic — and how herbal medicine + integrative strategies can help turn the tide.

The FiltrateJoel Topf @kidneyboy.bsky.social‬Swapnil Hiremath @hswapnil.medsky.socialNayan Arora captainchloride.bsky.socialSopia Ambruso @sophia-kidney.bsky.socialSpecial Guests Brendon Neuen @brendonneuen.bsky.social Associate Professor and Program Lead, Renal and Metabolic at The George Institute for Global Health. Nephrologist and Director of Kidney Trials at Royal North Shore Hospital.Neuen has had three prior appearances on Freely Filtered: EMPA Kidney, DUPLEX and Sparsentan in FSGS, FLOW and SemaglutideMuthiah Vaduganathan @mvaduganathan on X. Cardiologist at Brigham and Women's Hospital and Harvard Medical School. Assistant Professor of Medicine.Editing byJoel TopfThe Kidney Connection written and performed by Tim YauShow NotesDONATE to NephJC! Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes NEJM | NephJC SummaryFIDELIO Bakris et al, NEJM 2020 | NephJC Summary; subgroup throws doubt on efficacy of finerenone in patients on flozinsFIGARO Pitt et al, NEJM 2021; subgroups clearly shows finerenone works, flozins or notNEJM editorial (wrongly) saying do not use Flozins unless on RASi Don't use dual RAS blockade ONTARGET Yusuf et al, NEJM 2008; VA NEPHRON-D Fried et al NEJM 2013Why we cannot study finerenone in HFrEF (RALES Pitt et al NEJM 1999) Muthu is jealous of GFR slope and albuminuria surrogate endpoints and wants to borrow them for HFpEF (Inker et al EHJ 2025)Combination therapy and CV outcomes in hypertension (Wang et al JAMA Card 2024 on low dose combinations and BP; Egan et al Blood Pressure 2022 review of topic) CONFIRMATION HF trial registry entry (Finerenone and Empagliflozin in hospitalized patients with HF)23:20: Nayan and Swap miss a chance to say ‘de-flozination' to discuss stopping a flozin which would allow a patient to be included in the trial Finerenone is a CYP3A4 substrate (Heinig et al Clin Pharmacokinetics 2023); Useful list of CYP3A4 inducers and inhibitors Everyone should get an ABPM (Bugeja et al CMAJ 2022)EASiKIDNEY study design Albuminuria mediates CKD benefits with Finerenone (Agarwal et al Ann Intern Med 2023)GFR slope and Albuminuria and the FDA (Taylor et al eClin Med 2025) Dapagliflozin and Eplerenone combination crossover trial (Provenzano et al JASN 2022)Joel gets promoted! (PBFluids reflection) Bluesky NephJC Chat discussion on ‘renal remission' Withdrawal of Finerenone and worse outcomes from FINEARTS (Vaduganathan et al JACC 2025)Combination therapies Analysis from Brendan and Muthu (Neuen et al Circulation 2024)Do not use KFRE when GFR > 60 (KDIGO Practice Point 2.2.4: Note that risk prediction equations developed for use in people with CKD G3–G5, may not be valid for use in those with CKD G1–G2) Finerenone vs Spironolactone trial in Primary Aldosteronism (Hu et al Circulation 2025)FIND CKD trial design (Heerspink et al NDT 2025) FINE-ONE trial design (Heerspink et al Diab Res Practice 2023) Tubular SecretionsNayan keeping his chin up as Yankees lose and Mariners follow (MLB Playoffs)Sophia's adventures with Beekeeping (Royal Jelly?) Brendon loves listening to ‘Susan' by Raye Muthu is back into Taekwondo Swap is still reading Martha Wells (Witch King on GoodReads)Joel will be hiking the Laugavegur trail in Iceland

  Doctor Adam Weaver, MD About Dr. Weaver Dr. Weaver graduated from PHILADELPHIA COLLEGE OF OSTEOPATHIC MEDICINE in 2019 and completed a residency at Rowan University School of Osteopathic Medicine. Dr. Adam Weaver, DO is a Hospitalist in Blackwood, NJ and has 6 years experience. Dr. Weaver currently practices at Practice and are affiliated with Jefferson Stratford Hospital. Dr. Weaver has experience treating conditions like Bacterial Sepsis, Hypokalemia and Hypertensive Heart and Chronic Kidney Disease among other conditions at varying frequencies. At present, Dr. Weaver received an average rating of 3.7/5 from patients and has been reviewed 3 times. Dr. Weaver's office is not accepting new patients. Dr. Weaver accepts multiple insurance plans. Rebecca Reigns (Mrs. Weaver) REBECCA REIGNS - PHOTO/FASHION MODEL & CO STARRING IN THE NEW FEATURE "THE PONY MOVIE" Rebecca Reigns Can Be Seen in The Soon to be Released Film "PONY"  OFFICIAL WEBSITE https://cinemaddictfilms.wixsite.com/ponymovieofficial THE PONY MOVIE OFFICIAL TRAILER https://www.youtube.com/watch?v=qN-d6sYsH3U

This issue will review: 1.     Once-weekly Ultra-processed Foods and Diet Quality in Association With Long-term Weight Change and Progression to Type 2 Diabetes Among Individuals With a History of Gestational Diabetes Mellitus—A Prospective Study 2.     Plant-Based Dietary Patterns Associated With Reduced Risk of All-Cause Mortality in Diabetes Subgroups 3.     Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes- NEJM   4.     Risk of Phimosis Associated With SGLT2i Versus GLP-1RA: A Danish Cohort Study 5.     GLP-1 Receptor Agonists and Sight-Threatening Ophthalmic Complications in Patients With Type 2 Diabetes Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update   discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. For more information about each of ADA's science and medical journals, please visit Diabetesjournals.org. Hosts: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Chair-Department of Family Medicine, Abington Jefferson Health

This podcast is published open access in Advances in Therapy and is fully citeable. You can access the original published podcast article through the Advances in Therapy website and by using this link: https://link.springer.com/article/10.1007/s12325-025-03366-6. All conflicts of interest can be found online. This podcast is intended for medical professionals. Open Access This podcast is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The material in this podcast is included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

Willem J Kolff was an intern when he saw a 22 year old man die of kidney failure. He realised that the patient’s life could have been saved if his blood could have been detoxified. Willem set to work and developed the first ever dialysis machine (initially the ‘rotating drum kidney’). While dialysis is a lifesaving treatment, it is one that we hope to avoid for patients. In this episode, we discuss two topics that are the largest contributors to chronic kidney disease: Diabetes, and Hypertension. This is the story of Chronic Kidney Disease (Part 2). Our special guest: Dr Richard Phoon who is the Senior Medical Advisor at Westmead Hospital and has worked full-time as a Nephrologist at Westmead and Blacktown Hospitals since 2007. Useful links: CKD Management in Primary Care handbook (KHA) Link: https://kidney.org.au/health-professionals/ckd-management-handbook Kidney Health 4 Life: Kidney Health 4 Life – Better kidney health, for life Health professional webinar here: Kidney Health 4 Life Healthcare Professional Webinar – YouTube For health professionals looking for printed posters and brochures for their clinic or unit: Kidney Health 4 Life Print Materials Or contact the Kidney Health Australia Helpline on 1800 454 363See omnystudio.com/listener for privacy information.

In parts 1 and 2 we looked at studies that sought to determine the effects of semaglutide on kidney function. Today, in the final part of the series, we are going to discuss another such study called Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes by Perkovic et al., 2024. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

One in 10 Australians over the age of 18 years are living with signs of Chronic Kidney Disease (CKD) with the number of patients needing treatment for kidney failure has doubled in the last 20 years. Early detection and intervention can slow the progression of CKD by up to 15 years or longer. Our understanding of kidney disease can be traced back to Dr Richard Bright, one of the founding fathers of nephrology. He noted that heating a patient’s urine with kidney disease could form a precipitate – nowadays we’d call this albuminuria (albumin in the urine) and it is a marker of kidney damage. Today, there are a range of conditions that can reduce kidney function, cause kidney damage, and can cause significant morbidity and early mortality in patients. By screening patients, we can reduce the progression of CKD and significantly affect the health of patients in the long term. This is the story of Chronic Kidney Disease (Part 1). Our special guests: Maddie Williams who is a Registered Nurse with Kidney Health Australia who was diagnosed with kidney disease at the age of 17 requiring haemodialysis, peritoneal dialysis, and received a renal transplant. Dr Richard Phoon who is the Senior Medical Advisor at Westmead Hospital and has worked full-time as a Nephrologist at Westmead and Blacktown Hospitals since 2007. Useful links: CKD Management in Primary Care handbook (KHA) Link: https://kidney.org.au/health-professionals/ckd-management-handbook Kidney Health 4 Life: Kidney Health 4 Life – Better kidney health, for life Health professional webinar here: Kidney Health 4 Life Healthcare Professional Webinar – YouTube For health professionals looking for printed posters and brochures for their clinic or unit: Kidney Health 4 Life Print Materials Or contact the Kidney Health Australia Helpline on 1800 454 363 Listen: This Medical Life podcast is available on all podcasting services and Spotify. Help support us on our donation page.See omnystudio.com/listener for privacy information.

On continue notre série goutteuse! Dans ce 61ème épisode du Pharmascope, Nicolas, Sébastien et Isabelle discutent des mesures non pharmacologiques et du traitement prophylactique de la goutte. Les objectifs pour cet épisode sont les suivants: Expliquer les mesures non pharmacologiques utilisées dans le traitement chronique de la goutte Identifier les indications pour débuter un traitement prophylactique en goutte Expliquer les bénéfices et les risques associés aux traitements prophylactiques en goutte   Ressources pertinentes en lien avec l'épisode Lignes directrices portant sur la prise en charge de la goutte FitzGerald JD et coll. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Rheumatol. 2020;72:879-95. Richette P et coll. 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Ann Rheum Dis. 2020;79:31-8. Qaseem A et coll. Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2017;166:58-68. Articles de revue portant sur la prise en charge de la goutte Drug and Therapeutics Bulletin. Latest guidance on the management of gout. BMJ. 2018;362:k2893. Sidari A, Hill E. Diagnosis and Treatment of Gout and Pseudogout for Everyday Practice. Prim Care. 2018;45:213-36. Dugré N. L'hyperuricémie et la goutte. Québec Pharmacie. Juin/juillet 2015. 25p. Études portant sur les traitements chroniques de la goutte Badve SV et coll. Effects of Allopurinol on the Progression of Chronic Kidney Disease. N Engl J Med. 2020;382:2504-13. Doria A et coll. Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes. N Engl J Med. 2020;382:2493-2503. Kimura K et coll. Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial. Am J Kidney Dis. 2018;72:798-810. Schumacher Jr HR et coll. Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial. Arthritis Rheum. 2008;59:1540-8. Seth R et coll. Allopurinol for chronic gout. Cochrane Database Syst Rev. 2014;10:CD006077. Ramasamy SN et coll. Allopurinol Hypersensitivity: A Systematic Review of All Published Cases, 1950–2012. Drug Saf. 2013;36:953-80. White WB et coll. Cardiovascular safety of febuxostat or allopurinol in patients with gout. N Engl J Med 2018;378:1200-10.

Darshali Vyas is a pulmonary and critical care fellow at Massachusetts General Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.A. Vyas, L.G. Eisenstein, and D.S. Jones. The Race-Correction Debates — Progress, Tensions, and Future Directions. N Engl J Med 2025;393:1029-1036.

Dr. Jeanine Cook-Garard learns about chronic kidney disease — a serious condition that affects more than 1 in 7 adults in the U.S., often without any early symptoms. We'll talk about what causes it, who's at risk, and how it can be detected and managed before it leads to kidney failure.  Let's learn how to protect your kidneys and take control of your health from her guest, Dr. Stephen Fishbane, Chief of Division of Medicine for Kidney Diseases and Hypertension, at Long Island Jewish Medical Center and North Shore University Hospital, part of Northwell Health. He is also a Professor at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell.

The Journal of Rheumatology's Editor-in-Chief Earl Silverman discusses this month's selection of articles that are most relevant to the clinical rheumatologist. Modifiable Lifestyle Factors, Genetic Susceptibility, and Incident Radiographic Axial Spondyloarthritis - doi.org/10.3899/jrheum.2025-0042 Prevalence, Risk Factors, and Outcomes of Chronic Kidney Disease in Patients With Systemic Lupus Erythematosus With and Without Lupus Nephritis - doi.org/10.3899/jrheum.2024-1087 Outcomes in Systemic Sclerosis–Associated Interstitial Lung Disease Based on Serological Profiles With a Focus on Anticentromere and Anti-RNA Polymerase III Antibodies - doi.org/10.3899/jrheum.2024-1063 Clinically Inactive Disease and Remission in Patients With Juvenile Idiopathic Arthritis Receiving Tofacitinib: Post Hoc Analysis of a Phase III Trial - doi.org/10.3899/jrheum.2024-0536 Long-Term Effectiveness and Safety of Denosumab for Osteoporosis in Patients With Rheumatic Diseases - doi.org/10.3899/jrheum.2024-1321

In this podcast, expert Suneel Udani, MD, discusses the management of chronic kidney disease (CKD) and CKD-associated fluid overload, including an overview of treatment guidelines and various available therapies.

Alice Sheridan, MD, FASN, and Martina McGrath, MD, FASN, speak with guest editors Daniel W. Coyne, MD, and Morgan B. Schoer, MD, about their editorial "Parathyroidectomy for Treatment of Hyperparathyroidism in CKD" from nephSAP Volume 24, Number 3.

Alice Sheridan, MD, FASN, and Martina McGrath, MD, FASN, speak with guest editors Daniel W. Coyne, MD, and Morgan B. Schoer, MD, about their editorial "Parathyroidectomy for Treatment of Hyperparathyroidism in CKD" from nephSAP Volume 24, Number 3.

Send us a textWelcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2024:Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (FINEARTS-HF) (0:00 – 4:09)Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA) (4:10 – 9:28)Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (FLOW) (9:29 – 14:23)Tirzepatide for Metabolic-Dysfunction Associated Steatohepatitis with Liver Fibrosis (SYNERGY-NASH) (14:24 – 20:28)Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (BALANCE) (20:29 – 23:59)And for the Good Stuff:Toronto Star Santa Claus Fund, Calgary Food Bank, Epilepsy Canada (24:00 - 25:23)Calling keen trainees!Trainees, med students, residents: The Rounds Table and Trial Files (https://trialfiles.substack.com/) are looking for keen individuals to support our efforts.Reach out to fralickmpf@gmail.com if you are interested in getting involved. Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the simultaneous initiation of SGLT2 inhibitors and finerenone (a nonsteroidal mineralocorticoid receptor antagonist) in persons with chronic kidney disease and type 2 diabetes. Here we go!Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes (0:00 – 9:28).Calling keen trainees! (9:29 - 10:28)Trainees, med students, residents: The Rounds Table and Trial Files are looking for keen individuals to support our efforts.Trial Files is a free monthly newsletter on practice-changing trials, delivered straight to your inbox (https://trialfiles.substack.com/).Reach out to fralickmpf@gmail.com if you are interested in getting involved. Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Moderator: James P. Rathmell, M.D. Participants: Nikolay O. Kamenshchikov, M.D. and Lorenzo Berra, M.D. and Kamrouz Ghadimi, M.D. Articles Discussed: Perioperative Nitric Oxide Conditioning Reduces Acute Kidney Injury in Cardiac Surgery Patients with Chronic Kidney Disease (the DEFENDER Trial): A Randomized Controlled Trial Nitric Oxide and Kidney Injury after Cardiac Surgery: A Solution Looking for a Problem

Did you know that people who have received a kidney transplant are at a much higher risk for skin cancer? We sat down with experts to discuss how you can lower your risk. In this episode we heard from: Dr. Cerrene Giordano is a dermatologist and Mohs Micrographic surgeon at Roswell Park Comprehensive Cancer Center in Buffalo, New York. She specializes in treating skin cancers, particularly in patients who are high risk such as those who have received organ transplants, have weakened immune systems, or a genetic predisposition to skin cancer development. Her expertise includes skin cancer surgery, wound reconstruction, and the management of skin cancers such as melanoma, basal cell carcinoma, and squamous cell carcinoma, to name a few. Dr. Giordano is also involved in research aimed at improving pain management following dermatologic surgeries and exploring advanced imaging techniques to enhance surgical outcomes. Kent Bressler is a retired RN who was diagnosed with FSGS in 1984, and received a living donor transplant from his brother Kip in 1987. Kent is an active advocate for preemptive kidney transplant and has on the recommendation of NKF worked closely with the DoD and PCORI as a consumer peer reviewer. He is an NKF peer mentor and advocate who has collaborated on an editorial “Change in Albuminuria and GFR as End Points for Clinical Trials in Early Stages of Chronic Kidney Disease,” published in AJKD in 2019. He will also be participating in the development of the new NKF Patient Network serving on the Data Input and Integration Committee. He has been an active hill advocate for the NKF for six years and was the proud recipient of the 2017 Richard K. Salick Advocacy Award. Kent is also an Army Veteran and retired from the Veterans administration as an RN. He is the co-founder of Kidney Solutions a not for profit program in Texas that assists patients and families in the transplant process and in finding a donor. He is currently an assistant team leader for Region 7. Kent and Cathy Bressler have been married for 56 years and their family consists of Gretchen and Todd Rossington and their son Colt and Celeste and Alex Brown and their children John Banks, Catherine and Alexis Brown. Risa Simon is a passionate author, speaker, mentor, kidney patient coach and advocate. As the founder and CEO of The Proactive Path and the TransplantFirst Academy, her mission is to help all kidney disease patients advocate for their best life possible—the life she now lives. As a preemptive kidney transplant recipient, Risa was able to circumvent the need for dialysis. This is her hope for all eligible kidney patients. Risa gives back a good portion of her time by serving on various advisory committees, such as the National Kidney Foundation's (NKF's) Kidney Action committee, the American Association of Kidney Patients (AAKP) program and convention committees and she chairs the Phoenix Chapter's Polycystic Kidney Disease (PKD) education committee.  She is also a member of the PKD Legacy Society and serves as a Peer Mentor for the National Kidney Foundation (NKF). Risa's message is all about empowering kidney patients to bring their voice to life.    Additional Resources: Dr. Cerrene Giordano Protect the Skin You're In Do you have comments, questions, or suggestions? Email us at NKFpodcast@kidney.org. Also, make sure to rate and review us wherever you listen to podcasts.  

Kent Bressler talks with Josie Maier, co-director of Project Donor—a nonprofit offering free support to living organ donor candidates. Kent reflects on his journey as a living donor kidney transplant recipient and his recent triumph over cancer. Josie sheds light on key challenges in organ donation, especially how BMI restrictions can prevent otherwise willing individuals from donating. Project Donor works to shift the conversation by helping potential donors overcome reversible barriers through free weight loss programs, smoking cessation resources, and therapy. Together, Kent and Josie highlight the urgent need for more living kidney donors and the importance of awareness. Listen in and discover how you can make a difference in this life-saving mission. For more information about Project Donor, visit projectdonor.org and to connect with Kidney Solutions, go to kidneysolutions.org. Host: Kent Bressler Producer: Jason Nunez Remember to keep breathing, and don't miss the next amazing episodes of Kent's Kidney Stories!  

Join us for an inspiring episode of the Diary of a Kidney Warrior Podcast as we sit down with Ravi—a fellow Kidney Warrior whose story is one of courage, connection, and unshakeable will. From his unexpected diagnosis of Chronic Kidney Disease (CKD) to life on dialysis, Ravi opens up about the challenges and triumphs that have shaped his journey.   What began as a routine post-holiday health concern quickly became a life-altering revelation. Ravi walks us through the early warning signs, the shock of diagnosis, and the complexities of seeking care amid a global pandemic. As dialysis buddies turned friends, Ravi and our host share a powerful camaraderie that highlights the strength found in community.   In this candid conversation, Ravi speaks openly about the physical, mental, and emotional toll of CKD—detailing side effects, collapsing from poor health, and the resilience needed to push through. Balancing a demanding career in IT, he reveals how he copes with the daily realities of dialysis and the hope of an eventual transplant.   Whether you're newly diagnosed or supporting someone with CKD, Ravi's insights offer encouragement, practical advice, and heartfelt wisdom. He champions the importance of early detection, mental well-being, and finding purpose amidst the struggle.  

Dr. Thomas Weims, Professor at UC Santa Barbara, shares his revolutionary findings on treating polycystic kidney disease through ketogenic interventions. After 25 years of research, his lab accidentally discovered that ketosis dramatically halts and even reverses PKD progression—something previously thought impossible. The medical establishment had long maintained that PKD, a genetic disease affecting 600,000 Americans, was untreatable through dietary means. Yet Weims' research demonstrates that beta-hydroxybutyrate (BHB), the primary ketone produced during ketosis, shows more potent effects than any pharmacological intervention his team tested. In a groundbreaking clinical trial, patients on a ketogenic diet experienced improved kidney function and reduced kidney volume in just three months—the first time such reversal has ever been documented in PKD. Weims explains the science behind this therapeutic approach, how it challenges entrenched medical dogma, and why this metabolic therapy may benefit all forms of chronic kidney disease. This conversation exposes how decades of medical education about diet and kidney health have been based on hypothetical papers rather than clinical evidence, offering hope to millions suffering from progressive kidney conditions.BIG IDEA"What we found more recently is that the progression of polycystic kidney disease is not really driven by gene mutations as previously thought—a patient inherits a bad gene, but that doesn't necessarily mean they will have rapidly progressing PKD."Gary Taubes Contact InfoWebsite: https://uncertaintyprinciples.substack.com/Website: https://garytaubes.com/Send Dr. Ovadia a Text Message. (If you want a response, include your contact information.) Dr. Ovadia can not respond here. To contact his team please email team@ifixhearts.com If you like what you hear, I wanna make it easier for you to take action on your health.Head over to i fix hearts.com/book to grab a copy of my book, Stay Off My Operating Table, and if you're ready to go deeper or talk to someone from my team, just go to i fix hearts.com/talk. Stay Off My Operating Table on X: Dr. Ovadia: @iFixHearts Jack Heald: @JackHeald5 Learn more: Stay Off My Operating Table on Amazon Take Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart Health Jack Heald's website: CultYourBrand.com Theme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 25 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update   discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. Welcome to diabetes core update where every month we go over the most important articles to come out in the field of diabetes. Articles that are important for practicing clinicians to understand to stay up with the rapid changes in the field.  This issue will review: 1.    Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes 2.    Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension Meta-Analysis 3.    The Diabetes Prevention Program and Its Outcomes Study: NIDDK's Journey Into the Prevention of Type 2 Diabetes and Its Public Health Impact 4.    Comparative effectiveness of alternative second‐line oral glucose‐lowering therapies for type 2 diabetes: a precision medicine approach applied to routine data 5.    Phase 3 Trial of Semaglutide in Metabolic Dysfunction– Associated Steatohepatitis   For more information about each of ADA's science and medical journals, please visit Diabetesjournals.org. Hosts: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Chair-Department of Family Medicine, Abington Jefferson Health

Send us a textWelcome back Rounds Table Listeners! Today we have the next episode in our Clinical Practice Guidelines series. Drs. Mike and John Fralick discuss the top takeaways from the 2024 KDIGO Clinical Practice Guidelines for chronic kidney disease. Here we go!1. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (0:00 - 24:24)Access the KDIGO 2024 "Top 10 Takeaways" PDFs here: https://kdigo.org/guidelines/ckd-evaluation-and-management/The Good Stuff:Nephrology Trial Files - https://nephrotrialfiles.substack.com/ (24:25 - 24:48)The Phoenician Scheme (24:49 - 25:33)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textThis recording features audio versions of Month Year Journal of Vascular and Interventional Radiology (JVIR) abstracts:Optimal Timing of Percutaneous Cholecystostomy across Different Grades of Acute Cholecystitis: A Retrospective Cohort Study ReadGallbladder Cryoablation for Calculous Cholecystitis Initially Treated with Percutaneous Drainage: A Prospective Trial in High-Risk Patients ReadComparative Prognostic Utility of Updated Model for End-Stage Liver Disease Scores for Prediction of Early Mortality after Transjugular Intrahepatic Portosystemic Shunt Creation ReadLong-Term Outcomes of Angioplasty and Stent Placement for Portomesenteric Vein Obstruction following Hepatobiliary and Pancreatic Surgery ReadThe Impact of Chronic Kidney Disease on Amputation and Death Rates in Patients with Peripheral Artery Disease in the United States ReadPercutaneous Microwave Ablation of Small (

Kent Bressler welcomes Glenna Frey, MSN, APRN-CNS. She has dedicated over 40 years to nephrology nursing, specializing in hemodialysis, peritoneal dialysis, and kidney transplantation. In 2017, she donated a kidney to a stranger at the Cleveland Clinic. The following year, she co-founded Kidney Donor Conversations (KDC), a nonprofit providing education and support for living kidney donation with her daughter, Amanda. Glenna serves as executive director of KDC and frequently presents programs on living kidney donation. She is a member of the American Nephrology Nurses Association and the National Kidney Donation Organization. She volunteers with the National Kidney Foundation and other kidney-focused groups. Her connection to kidney disease and transplantation is deeply personal. Many of her relatives, including her husband Bob, have Polycystic Kidney Disease (PKD). Bob has undergone dialysis and is now living with his second kidney transplant from a living donor. Her children, Amanda and Sawyer, also have PKD but currently maintain normal kidney function. Glenna is a published author and contributor to several works on kidney donation and nephrology nursing, including In Pursuit of a Better Life: The Ultimate Guide for Finding Living Kidney Donors, Thriving Post Kidney Transplant, and the Nephrology Nursing Journal. Additionally, she served as a reviewer for the 4th edition of Contemporary Nephrology Nursing. She is the author of the book Understanding Living Kidney Donation: The Best Treatment for Kidney Disease, now available on Amazon. Glenna also specializes in holistic therapies, holds a Black Belt in Tae Kwon Do, and is a Hula Hoop instructor. She resides in Northwest Ohio with her husband and enjoys time with her cat, chocolate lab, as well as crocheting, and native plant gardening. Glenna's pride and joy are her children, Amanda and Sawyer, and her granddaughter, Zora. For inquiries, contact: https://www.linkedin.com/in/glennafreyrnkidneydonor/ or visit https://www.facebook.com/LivingKidneyDonationBook For more information on Kidney Solutions and to join our supportive community, visit kidneysolutions.org Host: Kent Bressler Producer: Jason Nunez Remember to keep breathing, and don't miss the next amazing episodes of Kent's Kidney Stories!  

Send us a textWelcome back Rounds Table Listeners! Today we have another special episode— Trial Files turns two years old this June, and we're celebrating with an episode summarizing the Top 5 RCTs in the Trial Files catalogue to date. Dr. Mike Fralick takes us through five trials in 15 minutes. Here we go!1. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (0:00 - 3:08)2. Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (3:09 - 5:37)3. Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis (5:38 - 8:33)4. Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (8:34 - 11:22)5. Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (11:23 - 13:23)Happy 2nd Birthday, Trial Files!A free monthly newsletter on practice-changing trials, delivered straight to your inbox-- sign up at https://trialfiles.substack.com/ (13:24 - 14:19)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Alice Sheridan, MD, FASN, and Martina McGrath, MD, FASN, speak with guest editors Dr. Reaves and Dr. Sarnak on "Benefits and risks of intensive blood pressure control in CKD patients: what does the current evidence tell us?" from nephSAP Vol 24, No 2.

Alice Sheridan, MD, FASN, and Martina McGrath, MD, FASN, speak with guest editors Dr. Reaves and Dr. Sarnak on "Benefits and risks of intensive blood pressure control in CKD patients: what does the current evidence tell us?" from nephSAP Vol 24, No 2.

In this podcast, Dr. Wendy St. Peter and Dr. Katie Cardone discuss the AJHP theme issue on the management of chronic kidney disease with host and AJHP Editor in Chief Dr. Daniel Cobaugh. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.

In this powerful and deeply personal episode of Diary of a Kidney Warrior Podcast, we meet Christy—an extraordinary kidney warrior whose story of resilience will inspire anyone facing life's toughest battles.   Christy takes us back to 2006, when a life-threatening crisis landed her in a coma, leading to kidney failure caused by septicaemia and peritonitis. What followed was nearly two decades of living with chronic kidney disease (CKD)—a journey marked by dialysis as a young adult, the heartbreak of a failed transplant, and the constant balancing act of managing additional health complications.   But Christy's story doesn't stop at survival. She shares how she transformed her adversity into advocacy, building a vibrant online community and launching her own podcast, Chronically Christy, to connect with and uplift other kidney patients.   With honesty and wisdom, Christy speaks about:

Drs Carol H. Wysham and Liana K. Billings discuss how to incorporate SGLT2 inhibitors and GLP-1 receptor agonists into the management of patients with type 2 diabetes and chronic kidney disease. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002049. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Type 2 Diabetes Mellitus https://emedicine.medscape.com/article/117853-overview Chronic Kidney Disease (CKD) https://emedicine.medscape.com/article/238798-overview Global, Regional, and National Burden of Chronic Kidney Disease Due to Diabetes Mellitus Type 2 From 1990 to 2021, With Projections to 2036: A Systematic Analysis for the Global Burden of Disease Study 2021 https://pubmed.ncbi.nlm.nih.gov/40034386/ Advantages, Limitations, and Clinical Considerations in Using Cystatin C to Estimate GFR https://pubmed.ncbi.nlm.nih.gov/36514729/ New Creatinine- and Cystatin C-Based Equations to Estimate GFR Without Race https://pubmed.ncbi.nlm.nih.gov/34554658/ Effects of Semaglutide on Chronic Kidney Disease in Patients With Type 2 Diabetes https://pubmed.ncbi.nlm.nih.gov/38785209/ Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy https://pubmed.ncbi.nlm.nih.gov/30990260/ Dapagliflozin in Patients With Chronic Kidney Disease https://pubmed.ncbi.nlm.nih.gov/32970396/ Empagliflozin in Patients With Chronic Kidney Disease https://pubmed.ncbi.nlm.nih.gov/36331190/ Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2025 https://pubmed.ncbi.nlm.nih.gov/39651975/ CKD Early Identification & Intervention Toolkit https://kdigo.org/wp-content/uploads/2019/01/ISN_KDIGO_EarlyScreeningBooklet_WEB_updatedOct11.pdf Combination Therapy as a New Standard of Care in Diabetic and Non-Diabetic Chronic Kidney Disease https://pubmed.ncbi.nlm.nih.gov/39907542/ Living With Chronic Kidney Disease and Type 2 Diabetes Mellitus: The Patient and Clinician Perspective https://pubmed.ncbi.nlm.nih.gov/36282450/

In this episode of Kidney Talk, Lori welcomes Dr. Richard Johnson - renowned nephrologist, author of Comprehensive Clinical Nephrology, and a pioneer in kidney disease research. Together, they dive into the fascinating connection between gut health and chronic kidney disease, exploring how good bacteria can support kidney function. Dr. Johnson shares insights on probiotics like Renadyl, leaky gut syndrome, and how gut imbalances might impact people who are on dialysis or have elevated creatinine levels. This enlightening conversation uncovers why gut health matters more than we ever imagined.

The authors evaluate the efficacy and safety of emerging therapeutic strategies for CKD management, including sodium-glucose cotransporter 2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP-1RA), finerenone, sacubitril/valsartan, and potassium binders. Read the full text manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.70014.

Dr. Centor discusses recent Kidney Disease: Improving Global Outcomes clinical recommendations for the care of patients with chronic kidney disease.

In this podcast, Dr. Valentin Fuster reviews findings from the SUMMIT trial, which examined how tirzepatide impacts patients with obesity-related heart failure with preserved ejection fraction (HFpEF) and chronic kidney disease (CKD). The study revealed that while tirzepatide improved cardiovascular outcomes and slightly boosted kidney function, the benefits in CKD patients may stem from mechanisms beyond glomerular filtration alone.

View the Show Notes For This Episode Dr. Robin Rose discusses Kidney Care with Peptides with Dr. Ben Weitz. [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]   Podcast Highlights In this episode of the Rational Wellness Podcast, Dr. Ben Weitz hosts Dr. Robin Rose to discuss crucial insights into kidney health. They explore the kidney's functions, including filtering blood, regulating electrolytes, and converting vitamin D. The conversation delves into chronic kidney disease, highlighting that symptoms can arise even in stage two when GFR drops below 60. Dr. Rose emphasizes the importance of early detection and intervention, discussing concepts such as uremic dysbiosis, endothelial damage, leaky gut, and the impact of toxins. They also touch on natural and supplemental approaches to support kidney health, like using bio-regulator peptides, nutritional therapy, and plant-based diets. Additionally, Dr. Rose shares her personal experience with kidney cancer and the insights she gained during her journey to recovery.   00:26 Understanding Kidney Functions and Chronic Kidney Disease 02:10 In-Depth Discussion with Dr. Robin Rose 02:34 The Complexities of Kidney Health 04:28 Kidney and Gut Health Connection 04:54 Challenges in Measuring Kidney Function 08:48 Managing Kidney Health Through Diet and Lifestyle 28:43 Nutritional Supplements for Kidney Health 33:23 Butyrate and Gut Health 33:56 Cardiovascular Markers and Genomics 34:59 Kidney Health Botanicals 37:31 Peptides and Their Benefits 43:06 Bio-Regulator Peptides 51:31 Personal Kidney Health Journey 52:48 Hydration and Herbal Teas 54:40 Final Thoughts and Resources     ________________________________________________________________________________________________________ Dr. Robin Rose is a Medical Doctor and an expert at supporting kidney health using a wholistic approach and peptides.  She has recently published a book, Renology Peptides: Kidney Success with Bioregulator Peptides. Renology Peptides is a comprehensive clinical volume that presents an evidence-guided scholarly tool to deepen understanding of regenerative kidney medicine and bioregulator peptides. Her website is Renology is Kidney Success.    Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure.  Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

https://www.nejm.org/doi/full/10.1056/NEJMoa2204233

This podcast will discuss an approach to pediatric chronic kidney disease. The podcast was created by Alexis Filyk, a second-year medical student at the University of Alberta, and Dr. Michelle Ruhl, a pediatric nephrologist at the Stollery Children's Hospital in Edmonton, Alberta.

Big Pharma pays billions for direct-to-consumer TV drug ads—is it time to ban them? Focused ultrasound obliterates liver tumors with minimal side effects; Nurse tricks woman into believing she's dying of cancer to cash in on her $1.5 million life insurance policy; Arizona bans insurance denial by AI automated systems; Study overturns view that very low-carb diets are bad for kidney disease patients; Strategies for reviving a lagging thyroid.

Why does a potentially deadly condition that affects 1 in 7 adults fly under the radar, undetected and undiscussed? Join us on this episode of Quality Matters as we explore Chronic Kidney Disease (CKD), a silent killer that's finally coming into the limelight of quality improvement.Our conversation begins with Dr. Ben Oldfield, a primary care physician, who sheds light on the startling prevalence and hidden complexities of CKD. Why is it so hard to detect, even with simple blood and urine tests? And why does this condition, despite its extensive impact, often get lost in the shuffle of busy health care visits?We'll unpack the challenges of diagnosing and managing CKD, exploring the emotional weight the diagnosis carries for patients and the hurdles clinicians face in communicating about it. Discover why CKD is a “loaded term” and how we can shift the narrative from fear to empowerment.But that's not all. We'll also tackle the big picture: How CKD fits into the broader landscape of cardiovascular, kidney, and metabolic (CKM) disorders. Could a holistic approach to these interconnected conditions revolutionize patient care?The conversation ends with Ben's thoughtful observations on how classic literature, particularly epic poetry, helps doctors make sense of health care's emotional complexities, connect with patients and find empowerment in the face of life and death.Join us as we explore how we can move CKD from the sidelines to the front lines of quality improvement, and how collaborative, longitudinal care can make a real difference.Key Quote:“Thinking about chronic kidney disease is a longitudinal process. It's only half the story to make the diagnosis in a snapshot in time. What's the follow up like? How are we doing with the patient over time? Because oftentimes quality measures can look at things in a snapshot in time. Chronic kidney disease really begs us to think more longitudinally.”“Benjamin Oldfield, MDTime Stamps:(02:54) The Silent Nature of CKD(07:05) Quality Measurement and CKD(11:08) The Link Between CKD and Cardiovascular Kidney Metabolic syndrome(13:06) CKD and CKM as Quality Priorities (15:45) Narrative Medicine and Personal InsightsLinks:NCQA Kidney Health ToolkitConnect with Benjamin Oldfield

The Clare branch of the Irish Kidney Assocation says it's "lobbying very hard" for a dialysis unit in Clare this World Kidney Day. In conjunction with the annual awareness day which has rolled around again, the Irish Kidney Association, or IKA, has launched its '1 in 10 People' campaign to shine a light on kidney health awareness. The campaign, according to the IKA, is intended to make people more aware of kidney-related health conditions. It's estimated that one in 10 people in Ireland and one in seven over the age of 50 are living with Chronic Kidney Disease or CKD. Of these, a startling 98% don't know they have the condition which is on track to be the fifth leading cause of death here by 2040. Clare people in need of renal care currently have to go either to University Hospital Limerick or its satellite centre on the Dock Road in Limerick. While the HSE had at one point said Ennis Hospital would have a dialysis unit by the end of this year, this has now been pushed back to November 2026. Chairperson of the Clare branch of the IKA Dermot Hayes people here are travelling an exceptional distance to access the care they need. At this week's meeting of Clare County Council, Clarecastle Sinn Féín Councillor Tommy Guilfoyle tabled a motion seeking clarity on the delivery of the Ennis dialysis unit. Specifically, he's requested a precise timeline on the commencement of services, confirmation of its location, details of the contractor and confirmation of the project's current status. He says many in this county are confused and need answers as a matter of urgency.

Dr. Kirk Welker is Dr. Hiatt's guest this month. They discuss the research and collaboration involved in creating the State of Practice: ASNR Statement on Gadolinium-Based Contrast Agent Use in Patients with Chronic Kidney Disease, published in the February issue of AJNR. Be sure to visit our website to watch the video version of this podcast. (13:04)

Send us a textIn this episode, we have Dr. Lisa Dubrofsky (Nephrology, University of Toronto) speaking about the KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease.Host: Dr. Catherine Leurer (Geriatrics Fellow)Sound editing by:  Krzystof KowalikSupport the show

Nephrologist Manjula Tamura discusses the downsides of kidney dialysis, especially for old or frail patients. Her field has set its sights on offering alternatives, including supportive medical management without dialysis, dialysis in increments, wearable artificial kidneys, and transplanted kidneys from genetically modified pigs – in addition to advances in preventive care that can help humans avoid kidney failure in the first place. Dialysis can extend life, she says, but it is a lifestyle change. The goal is to ensure that every patient's choice aligns with their values and life goals, Tamura tells host Russ Altman in this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your quest. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Manjula Kurella TamuraConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest, Manjula Tamura, a professor of medicine and nephrology at Stanford University Medical School.(00:02:58) The Kidney's Vital RoleThe kidney's role and why its failure is life-threatening.(00:04:51) Causes of Kidney FailureThe leading causes of kidney failure in developed countries.(00:07:58) Kidney TransplantationThe feasibility, barriers, and supply challenges of kidney transplantation.(00:09:50) The Dialysis ProcessHow hemodialysis and peritoneal dialysis work and patient experiences.(00:14:07) The Evolution of Dialysis TreatmentThe history of dialysis and how Medicare's expansion influenced its use.(00:18:48) Study Design: Emulating Clinical TrialsUsing VA electronic health records to simulate trials on dialysis.(00:25:31) Findings: Survival vs. Time at HomeThe trade-offs between extended survival and reduced time at home.(00:27:02) Quality of Life and DialysisMeasuring quality of life impacts through electronic health records.(00:30:32) The Future of Kidney TreatmentsInnovations like xenotransplantation and wearable artificial kidneys.(00:33:04) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

Chronic kidney disease develops among 30% to 40% of people with type 1 or type 2 diabetes during their lifetime. Author Ian H. de Boer, MD, MS, of the University of Washington Division of Nephrology, discusses the evaluation and treatment of chronic kidney disease in patients with type 1 and type 2 diabetes with JAMA Senior Editor Karen Lasser, MD, MPH. Related Content: Diabetes and Chronic Kidney Disease

Send us a textHappy Holidays Rounds Table Listeners! For our penultimate episode of 2024, we are back with a special treat! This week, Drs. Mike and John Fralick chat about the top five RCTs published over the past year:Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (0:00 – 3:40).Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (3:40 – 9:00).Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (9:00 – 13:55).Tirzepatide for Metabolic-Dysfunction Associated Steatohepatitis with Liver Fibrosis (13:55 – 20:00).Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (the Balance Trial) (20:00 – 23:30).And for the Good Stuff:Toronto Star Santa Claus Fund, Calgary Food Bank, Epilepsy Canada (23:30 – 24:51).Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePodsSupport the show

Happy Holidays Rounds Table Listeners! For our penultimate episode of 2024, we are back with a special treat! This week, Drs. Mike and John Fralick chat about the top five RCTs published over the past year:Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (0:00 – 3:40).Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (3:40 – 9:00).Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (9:00 – 13:55).Tirzepatide for Metabolic-Dysfunction Associated Steatohepatitis with Liver Fibrosis (13:55 – 20:00).Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (the Balance Trial) (20:00 – 23:30).And for the Good Stuff:Toronto Star Santa Claus Fund, Calgary Food Bank, Epilepsy Canada (23:30 – 24:51).Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Host: Darryl S. Chutka, M.D.   Guest: Aleksandra Kukla, M.D. In 2023, an estimated 14% of all adults in the U.S. or just over 35 million individuals had chronic kidney disease and it's even more common in the elderly population affecting over 1/3 of those over the age of 65. It represents the 8th leading cause of death in the U.S. It's now known that chronic kidney disease is associated with systemic inflammation, which is responsible for a variety of complications including atherosclerosis and subsequent cardiovascular disease. Does kidney disease result in inflammation or does inflammation produce renal dysfunction? Are there inflammatory markers we could measure to assess this inflammation? Can we do anything to reduce the inflammation and if so, does it improve patient outcome? These are just some of the questions I'll be asking my guest, Aleksandra Kukla, M.D., from the Division of Nephrology at the Mayo Clinic as we discuss “Chronic Kidney Disease as a Systemic Inflammatory Syndrome”. These talks on Inflammation and Cardiometabolic Disease are sponsored by Novo Nordisk Learn more about this series HERE Connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Dr. Centor discusses reninbngiotensin system blockade in persons with advanced chronic kidney disease with Drs. Elaine Ku and Mark Sarnak.