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Send us a text00:00:00 - Surf's Up: Episode 6.9This conversation covers three topics. The first discusses the challenges of behavior change in dietary habits and ways governments can help, the second looks at what one can learn from wearing a CGM for 30 days, and the third celebrates the late Stephen Harrison while looking into the future of clinical trials and medical education. 00:06:12 - Global Think-Tank on SLD Roundtable, Part 3Behavior consultant Dr. Kristina Curtis joins Jörn Schattenberg, Louise Campbell and Roger Green to discuss issues related to patient-centered care. This conversation starts by focusing on the unique challenges that come with changing dietary habits. Changing this behavior is so challenging because the issues are so complex. People lack education about healthy eating habits. Even when they do, the high-pressure world in which we live often makes it easier simply to offer children fast food. Even parents who know better might allow their children (or spouses, or selves) not to eat vegetables after a trying day. The panel proceeds to discuss steps politicians can take to encourage healthier living and lifestyles if they wish, and why some are easier to execute than others. Finally, the group shares why they felt "enlightened" when leaving the SLD, and perhaps a little less alone. 00:21:34 - Newsmaker: Fatty Liver Alliance President Mike BetelThis interview with Fatty Liver Alliance President Mike Betel focuses on Year 3 of his 30-day Glucose Challenge. Mike wears a continuous glucose monitor (CGM) for the entire month of July and provides daily videos on LinkedIn and the Fatty Liver Alliance website discussing what he learned. The first year was dedicated to teaching the impact of eating badly and the second year was similar, but less egregious. This year, Mike, who is pre-diabetic, set the goal of keeping his glucose in a "normal" range of 70-140 mg/dl. He did so successfully 97-98% of the time over the month, and discusses some of the tricks he learned that help keep glucose in range over that time (HINT: walking 10-15 minutes after meals helps a lot!). He also shares hints about how to look at overall weight (it's the fat that matters, not simple weight), why it is not healthy to believe you must finish every bite of food put in front of you, and how all this relates to sleep and overall health. He also provides seeds for thought about ways manufacturers and providers might educate patients effectively on these issues. 00:53:11 - Expert: Summit Clinical Research Chief Academic Officer Naim AlkhouriThis interview occurred in late April during our episode celebrating Stephen Harrison. Naim chose this interview to annouce that he was joining Summit as Chief Academic Officer. The first part of this discussion focuses on Stephen on two levels: the personal history between Naim and Stephen and the nature of the contributions Stephen has made to the science of MASH, and particularly clinical trial design. The second part of the interview discusses Naim's new role, the diffrent kinds of teaching, training and medical education he sees as pivotal to the future of MASLD and MASH therapies, and the other elements of his new role. While discuss the role, he shares several bright, challenging insights about when MASH-ville is heading. 01:15:09 - ConclusionThe business report discusses vacations on the SurfingMASH team, upcoming episodes, and grateful notes from Ukrainian listeners.
Send us a textThis conversation is the second segment of SurfingMASH's coverage of the Global Think Tank on Steatotic Liver Diseases (#SLDThinkTank2025) held in Barcelona in June. It focuses on the kinds of feedback most likely to produce successful behavioral interventions.The conversation begins with Jörn discussing the Liver Screen Study, a "very ambitious effort" that starts with 30,000 members of the general European population, narrows down to a subgroup with liver disease, and then provides these individuals with information about MASLD and how to manage it, ultimately evaluating its impact. Many of these people did not know about liver disease before being informed they had it, and many changed their behavior as a result. Jörn links this to the EASL Amsterdam activity discussed last week in 6.7.1 and 6.7.2. Louise relates a story of speaking with Laurent Sandrin, Chairman of Echosens and inventor of FibroScan, who was "blown away by the reaction" to making FibroScans available and promoting this fact. Louise explained to Laurent that from her vantage point, FibroScan is "more than just the physical diagnostic. It has the power to engage populations," and, for many, provide the information and motivation they need to change behavior. Kristina describes how we can provide "biofeedback" like this, along with other behavioral strategies, to produce sustainable behavior change, which is far harder for an individual than simply reacting to a medical scare. She describes a model she deploys, the "Combi" model, which integrates an array of informational, motivational and behavioral items into an integrated, individualized approach. The conversation shifts to focus on environmental factors that work against long-term change. For someone with alcohol use disorder, this might be a family member who continues to consume large quantities of alcohol frequently. For someone living with obesity, it might be a favorite high-calorie dish...or even simply food advertising.In the final part of this conversation, Jörn states that the Think Tank steering committee invited politicians to help them understand why certain kinds of interventions — such as taxing medically harmful goods or limiting advertising — might be socially valuable, even if unpopular. The group discussed some governmental tactics that are effective and others that are not.
Send us a text00:00 - Surf's Up, Season 6 Episode 8The conversation addresses three issues that are distinct, yet each is pivotal to the future of MASLD and MASH therapies. The first, from the Global Think-Tank on Steatotic Liver Disease, considers how personal and digital approaches can be combined to form the most effective strategy for patient management. In the second, Global Liver Institute President and CEO Larry Holden joins Roger Green to discuss the new challenges in Washington stemming from the Trump Administration and RFK Jr. The final section is the conclusion of our recent drug development roundtable, examining drug classes we did not previously discuss, along with a thought on where combination therapy is likely to lead. 00:04:57 - Global Think-Tank on SLD Roundtable, Part 2Behavior consultant Dr. Kristina Curtis joins Jörn Schattenberg, Louise Campbell and Roger Green to discuss issues related to patient-centered care. This discussion focuses on the elements of successful behavior change and the importance of real-time, actionable feedback. The group discusses the interplay of diagnostic test feedback, real-time personal exchanges and AI-based algorithms in what Kristina terms a "hybrid therapy."00:18:39 - Newsmaker: Larry HoldenGLI President and CEO Larry Holden addresses two issues related to current goings-on in Washington. First, he acknowledges that we are in for "dark times" under the current administration, and describes some of the decisions and challenges we face. Second, he suggests what individuals and organizations can do to create the best possible situation -- and even some "wins" -- for people living with liver disease. These suggestions reflect his experiences during a 30-year career on Capitol Hill, prior to his joining GLI.00:46:15 - Drug Development Roundtable, Part 4Sven Francque joins Jörn, Louise and Roger to share an up-to-date look at drug development. This discussion focuses on PPARs, genetic medicines, and other emerging drug classes. Sven uses the example of the pan-PPAR lanifibranor to explore the idea that drug therapies can have an impact on the liver independent of their effect on fibrosis regression. The group proceeds to discuss other emerging drugs in development and their modes of action. One theme: over time, we may see prescribers consider using different therapies to address metabolic vs. liver-specific effects, often in combination.01:00:47 - Business ReportThanks to our listeners, Jörn's vacation, Welcome Regeneron
Send us a textThis conversation is the opening segment of SurfingMASH's coverage of the Global Think Tank on Steatotic Liver Diseases (#SLDThinkTank2025) held in Barcelona in June. Co-hosts Louise Campbell and Roger Green are joined by Dr. Kristina Curtis, Managing Director of Applied Behaviour Change, a UK-based consultancy. This discussion starts with co-host Jörn Schattenberg discussing the history and evolution of the first four Global Think-Tanks as the focus shifts from educating medical professionals about liver disease to incorporating a broader group of stakeholders, including politicians and non-hepatologist MDs, to break down siloes and create broader awareness. Co-host Louise Campbell describes the breadth of stakeholders necessary to address this pandemic fully. She explains how her work with transient elastography and the MyLife365.me app constitutes a form of behavioral therapy. Jörn describes the test as a diagnostic and comments that the treatment is what health professionals do with the results. Kristina says that the behavioral change that results comes from well-delivered feedback. She describes "hybrid interventions, digital interventions with a human in the loop." Louise discusses results from the EASL late-breaker that support these findings and goes on to discuss the role AI can play in medical practices.
00:00:00 - Surf's Up: Season 6 Episode 7Host Roger Green explains our recent vacation from publishing episodes, assures the audience that the podcast will continue weekly for months and years ahead, and discusses the episode's sections, covering the Global Think-Tank on Steatotic Liver Disease (SLD), the EASL patient screening activity and the increasing role of NITs in drug development. While introducing roundtable guests, he introduces first-time Surfer Dr. Kristina Curtis of the UK-based consultancy, Applied Behaviour Change.00:09:11 - Roundtable I: From the Global Think-Tank on SLDThis discussion starts with co-host Jörn Schattenberg discussing the history and evolution of the first four Global Think-Tanks as the focus shifts from educating medical professionals about liver disease to incorporating a broader group of stakeholders, including politicians and non-hepatologist MDs, to break down siloes and create wider awareness. Co-host Louise Campbell describes the breadth of stakeholders necessary to address this pandemic fully. She explains how her work with transient elastography and the MyLife365.me app constitutes a form of behavioral therapy. Jörn describes the test as a diagnostic and comments that the treatment is what health professionals do with the results. Kristina says that the behavioral change that results comes from well-delivered feedback. She describes "hybrid interventions, digital interventions with a human in the loop." Louise discusses results from the EASL late-breaker that support these findings and goes on to discuss the role AI can play in medical practices.00:23:50 - Newsmaker: Jose Willemse, Dutch Liver Patients Association This discussion covers two primary topics: (1) the Amsterdam screening activity that took place during EASL. Jose describes the phenomenal level of interest in this activity, in which hepatologists and APPs scanned 400 people per day for MASLD and MASH. Boosted by significant mass publicity in Amsterdam, the number of people seeking screening exceeded the 400/day quota, with some arriving in line hours before the scheduled start time and others traveling for hours to reach the site. Jose believes that with adequate publicity, efforts like these could be replicated around the world, but that the healthcare system lacks the necessary resources to do so. In terms of patient care, Jose emphasized the importance of sensitive yet frank conversations and helping patients appreciate the successes they are achieving. 00:53:45 - Roundtable II: NITs Increasing Role in Drug Development Sven Francque and Naim Alhouri joined Louise, Jörn and Roger for this roundtable, although Naim had dropped off by this time. The conversation starts with Louise noting that the goal of therapy is not simply to treat MASLD, but to achieve overall metabolic health, of which MASLD is a key component. Jörn states that we are on the path toward conducting clinical trials entirely with NITs as disease markers, which he describes as a "game changer" and Louise terms "exciting." She asks whether NITs can serve as the only trial surrogate. Jörn and Sven agree that we are not at that point yet, but we are headed in that direction. Jörn asserts that "nothing" will replace outcomes as the prerequisite for full approval and mentions the VCTE study group as demonstrating that a large NIT-based trial can prove effects on disease. Louise cautions that operator competency is a key, if overlooked, criterion for this kind of activity. Sven concurs and states that repeat measures are crucial in managing disease. Jörn notes that practices can serve as centers of care, but will need support from nutritionists and other professionals. 01:06:08 - Business ReportRoger highlights special September programming, indicates that new sponsors are on the way, and asks how many listeners find SurfingMASH on YouTube.
In the headlines: Saint Lucia's Prime Minister delivers the keynote address at a Global Think-Tank meeting in Morocco and; Sports personnel meet for final preparations for Sports Awards 2025. For details on these developments and more, visit www.govt.lc
Brenden Varma has served as a United Nations spokesperson and political affairs officer for over 20 years in New York, Baghdad, Jerusalem, Mogadishu and Pristina. He currently serves as the Deputy Director of the UN Information Center in Washington, DC. The UN Information Center works to inform, educate and update a wide range of groups, such as environmentalists, governmental agencies, businesses, DC based international institutions and the public. Public Opinion Polls over the decades show that Americans normally support the UN, depending on the issue, from 38%-84%. UN agencies assist in moving aircraft, mail, ships and weather information in international space, as well as working with Rotary International to eliminate the scourge of polio, assisting Ukrainians, empowering women, combatting climate change and human trafficking and promoting human rights. The UN's budget is smaller than that of the New York Police Department's. All 8 billion people on the planet are positively affected daily by a myriad of UN agencies.
Think tank Crisis Group outlines the 10 conflicts to watch in 2023 why Pakistan is included. Also, the opening spaces for non-western ‘middle powers' especially India. Editor-in-Chief @ShekharGupta assesses the array of conflicts – from Russia-Ukraine to Pakistan. Watch episode 1147 of #CutTheClutter Brought to you by @KiaInd ----more----Read Crisis Group's report here: https://www.crisisgroup.org/global/10-conflicts-watch-2023----more----Watch Azerbaijan & Armenia Blood Feud CTC here: https://m.youtube.com/watch?v=LW4j2MP29ns----more----Watch Azerbaijan & Armenia At war again CTC here: https://m.youtube.com/watch?v=6WjZa8f-Kj8----more----Watch Yemen War & UAE drone strikes CTC here: https://m.youtube.com/watch?v=WYO3ZHu4gI4
We discuss a wide range of topics from politics to global warming in a very interesting conversation. Be sure to check out their website at voiceofmankind.org for more information.Voice of Mankind is a non-profit Think Tank working to influence public opinion on issues that affect us all. We are here to make sense of this changing world. We provide original analysis, provoke thought, and enlighten on issues relevant to all of us. Our ideas are battle-tested in the real world every day by us. You should too. Have a question for me? No problem just ask away on social media Twitter @JWMediaDC Instagram – Jimwilliams200 and email at jimwilliamsmedia@gmail.com
The political divide in America got center stage treatment at the first Global Think Tank of this year's International Pastors & Leadership Conference. Four spiritual leaders, who have had the ears of U.S. Presidents, joined White House correspondent April Ryan for a discussion about issues, solutions, and the role of the church in the future of our country. It got real. It got animated. Even Bishop Jakes went from audience member to VERY active participant in this all too critical conversation. Learn more about your ad choices. Visit megaphone.fm/adchoices
The political divide in America got center stage treatment at the first Global Think Tank of this year's International Pastors & Leadership Conference. Four spiritual leaders, who have had the ears of U.S. Presidents, joined White House correspondent April Ryan for a discussion about issues, solutions, and the role of the church in the future of our country. It got real. It got animated. Even Bishop Jakes went from audience member to VERY active participant in this all too critical conversation.
The political divide in America got center stage treatment at the first Global Think Tank of this year's International Pastors & Leadership Conference. Four spiritual leaders, who have had the ears of U.S. Presidents, joined White House correspondent April Ryan for a discussion about issues, solutions, and the role of the church in the future of our country. It got real. It got animated. Even Bishop Jakes went from audience member to VERY active participant in this all too critical conversation. Learn more about your ad choices. Visit megaphone.fm/adchoices
The political divide in America got center stage treatment at the first Global Think Tank of this year's International Pastors & Leadership Conference. Four spiritual leaders, who have had the ears of U.S. Presidents, joined White House correspondent April Ryan for a discussion about issues, solutions, and the role of the church in the future of our country. It got real. It got animated. Even Bishop Jakes went from audience member to VERY active participant in this all too critical conversation.
Garyn Angel comes on Bulletproof Radio today to discuss the benefits of medical marijuana, how to avoid marijuana overdose, why you should stop smoking marijuana, and how butter can transform cooking. Garyn Angel is the Founder and CEO of MagicalButter.com, a Seattle-based technology company that has revolutionized botanical extractions with their award-winning appliance. He is the President of ThinkMB, a Global Think Tank that combines Traditional Chinese Medicine, cannabis, and modern day science. In 2014, Garyn was selected to the CNBC NEXT List for his work with Legal Marijuana. Prior to MagicalButter, he was the President of G. Angel & Associates, Inc., a leading Advanced Estate Planning and Tax Specialty firm. In 2008 he was named one of America’s Top Financial Planners by Reuters Advice Point. Garyn radiates positivity and wants everyone to be happy and healthy. Enjoy the show!
Garyn Angel comes on Bulletproof Radio today to discuss the benefits of medical marijuana, how to avoid marijuana overdose, why you should stop smoking marijuana, and how butter can transform cooking. Garyn Angel is the Founder and CEO of MagicalButter.com, a Seattle-based technology company that has revolutionized botanical extractions with their award-winning appliance. He is the President of ThinkMB, a Global Think Tank that combines Traditional Chinese Medicine, cannabis, and modern day science. In 2014, Garyn was selected to the CNBC NEXT List for his work with Legal Marijuana. Prior to MagicalButter, he was the President of G. Angel & Associates, Inc., a leading Advanced Estate Planning and Tax Specialty firm. In 2008 he was named one of America’s Top Financial Planners by Reuters Advice Point. Garyn radiates positivity and wants everyone to be happy and healthy. Enjoy the show!
Charles Luzar is Director of Crowdfundinsider.com as well as a member of the PR committee for the Crowdfunding Professional Association and a member of the CF 50, a Global Think Tank of Crowdfunding Industry Experts. We discuss equity-based crowdfunding and its role in the evolving world of Crowdfunding
The Club of Rome is a global think tank that deals with a variety of international political issues. It was founded in April 1968 and raised considerable public attention in 1972 with its report The Limits to Growth. The club states that its mission is "to act as a global catalyst for change through the identification and analysis of the crucial problems facing humanity and the communication of such problems to the most important public and private decision makers as well as to the general public." [1] Since 1 July 2008, the organization has its headquarters in Winterthur, Switzerland.