Podcasts about pharmaceuticals

Substance used to diagnose, cure, treat, or prevent disease

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Latest podcast episodes about pharmaceuticals

OffScrip with Matthew Zachary
Koby & Hannah's 2025 Holiday Podcast Spectacular

OffScrip with Matthew Zachary

Play Episode Listen Later Dec 30, 2025 28:46


The most anticipated annual tradition on Out of Patients returns with the 2025 Holiday Podcast Spectacular starring Matthew's twins Koby and Hannah. Now 15 and a half and deep into sophomore year, the twins deliver another unfiltered year end recap that longtime listeners wait for every December. What began as a novelty in 2018 has become a time capsule of adolescence, parenting, and how fast childhood burns off.This year's recap covers real moments from 2025 A subway ride home with a bloodied face after running full speed into that tree that grows in Brooklyn. Broadway obsessions fueled by James Madison High School's Roundabout Youth Ensemble access, including Chess, & Juliet, Good Night and Good Luck, and Pirates of Penzance holding court on Broadway. A Disneylanmd trip where the Millennium Falcon triggered a full system reboot. A New York Auto Show pilgrimage capped by a Bugatti sighting. All the things.The twins talk school pressure, AP classes, learner permit anxiety, pop culture fixation, musical theater devotion, and the strange clarity that comes with turning 15. The humor stays sharp, the details stay specific, and the passage of time stays undefeated. This episode lands where the show works best: family, honesty, and letting young people speak for themselves.FEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

OffScrip with Matthew Zachary
Hair Today, Gone Tomorrow: Jason Gilley

OffScrip with Matthew Zachary

Play Episode Listen Later Dec 23, 2025 40:20


Jason Gilley walked into adulthood with a fastball, a college roster spot, and a head of curls that deserved its own agent. Cancer crashed that party and took him on a tour of chemo chairs, pediatric wards, metal taste, numb legs, PTSD, and the kind of late night panic that rewires a kid before he even knows who he is.I sat with him in the studio and heard a story I know in my bones. He grew up fast. He learned how to stare down mortality at nineteen. He found anchors in baseball, therapy, and the strange friendships cancer hands you when it tears your plans apart. He owns the fear and the humor without slogans or shortcuts. Listeners will meet a young man who refuses to let cancer shrink his world. He fights for the life he wants. He names the truth without apology. He reminds us that survivorship stays messy and sacred at the same time. This conversation will stay with you.RELATED LINKS• Jason Gilley on IG• Athletek Baseball Podcast• EMDR information• Children's Healthcare of AtlantaFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

340B Insight
2025: The Year Rebates Took Shape

340B Insight

Play Episode Listen Later Dec 22, 2025 18:27


340B Insight wants to make our podcast the best it can be. To help us succeed, we'd like to hear your thoughts. Please take just a few minutes to complete our listener survey, and we will enter you in a drawing to win a $100 gift card! To participate, please go to 340bpodcast.org/survey.With monumental movement on 340B rebates, changes in Medicare and Medicaid payments, and evolving audit priorities, 2025 has been a transformative year in the world of 340B. We sit down with 340B Health Senior Manager of Policy and Compliance Rebecca Swartz to chronicle some of the biggest developments of such an eventful year and forecast what to expect in 2026.Rebates Take ShapeSwartz says 2025 will go down as the year that a rebate model shifted from a hypothetical approach pushed by drugmakers into a fully developed model with implementation criteria. The Health Resources & Services Administration (HRSA) approved plans for 340B rebate models set to take effect in January for nine of 10 drugs subject to the 2026 Medicare maximum fair prices. Rebates for the remaining drug on that list will kick in April 1. Swartz discusses how hospitals should prepare for this pilot program, which is set to upend decades of established 340B operations and impose intense financial and logistical burdens on safety-net hospitals nationwide.Medicaid, IRA Changes Set To Impact 340B HospitalsThis year also saw massive changes to Medicaid funding as well as Medicare pay changes under the implementation of the Inflation Reduction Act (IRA). Swartz says these developments are projected to shrink safety-net hospital margins even further. Renewed congressional focus is putting 340B in a high-profile spot, with potentially significant implications for the program and hospitals in the coming months.2026 Tips for HospitalsSwartz says she's identified two areas as more of a focus for HRSA audits this year: expanded scrutiny of offsite and on-site trial balances and the ways covered entities list shipping addresses. To prepare for possible shakeups in 2026, she recommends that covered entities begin and maintain cross-functional planning across departments and closely monitor denials, delays, and other costs from new rebate programs in addition to monitoring wholesale acquisition cost (WAC) changes and contract pharmacy developments.Resources340B Health Year-in-Review Webinar: 2025 Highlights and What's on the Horizon

The Morning Brief
Corner Office Conversation with Stefan Oelrich, Head of Pharmaceuticals Division, Bayer AG

The Morning Brief

Play Episode Listen Later Dec 22, 2025 26:09


As the global pharmaceutical industry enters a period of profound transition, this episode of Corner Office Conversation examines what lies ahead. Hosts Vikas Dandekar and Teena Thacker talk to Stefan Oelrich, Head of the Pharmaceuticals Division at Bayer AG, about the forces reshaping drug discovery and access from trade tensions and shifting innovation hubs to the promise and uncertainty of cell and gene therapies. Oelrich reflects on Europe’s struggle to stay competitive as capital and talent flow increasingly toward the US and China, and argues that meaningful reform will require faster regulation, leaner bureaucracy, and quicker patient access. He also addresses the looming loss of exclusivity for blockbuster drugs and outlines how Bayer plans to offset revenue impact with a packed pipeline of new launches. India emerges as both an opportunity and a test case, offering scale and growth while raising tough questions on affordability and access. At its core, the conversation asks whether breakthrough science can move fast enough to serve patients without losing public trust.You can follow Vikas Dandekar on his social media: X and Linkedin and read his Newspaper Articles.You can follow Teena Thacker on his social media: X and Linkedin and read her Newspaper Articles.Listen to Corner Office Conversation: Corner Office Conversation with Knight Frank’s William Beardmore-Gray and Shishir Baijal, Corner Office Conversation with Sridhar Vembu, CEO, of Zoho Corporation, Corner Office Conversation with Gunjan Soni, Country Managing Director, Youtube India, Corner Office Conversation with Elizabeth Reid, Head of Search, Google and much more. Catch the latest episode of “Corner Office Conversation” on: Spotify, Amazon Music, Apple Podcasts,and wherever you get your podcasts from.See omnystudio.com/listener for privacy information.

Evolve CPG - Brands for a Better World
Honey for Health with Madelyn Morris of Mickelberry Gardens

Evolve CPG - Brands for a Better World

Play Episode Listen Later Dec 19, 2025 62:18


In this conversation, Madelyn Morris, co-owner of Mickelberry Gardens, shares insights into her journey of creating a honey herbal wellness brand that specializes in oxymels – a tonic made of honey, vinegar, and herbs. She discusses the benefits of oxymels, the importance of sourcing local and organic ingredients, and the value of B Corp certification. Madelyn share their founding story, the challenges they faced in the early years of the business, and what they've been able to accomplish in their 15 years in business. She offers advice for aspiring entrepreneurs, highlighting the importance of passion and adaptability in business, and we wrap up with Madelyn sharing her vision of a better world.Takeaways:Mickelberry Gardens combines honey and herbalism for wellness.Oxymels are a tonic of honey, vinegar, and herbs with roots back to ancient Greece.Natural remedies are increasingly replacing pharmaceuticals.Sourcing local and organic ingredients is crucial for quality.Starting small allows for sustainable growth.B Corp certification provides a framework for improvement.Having a strong business partner can make a big difference.Adapting to change is essential for business longevity.Building a resilient business takes time and effort.A better world is one where all living things thrive.Sound bites:“The word oxymel is from Latin. Oxy is acid and mel is sweet or honey.”“Hippocrates, the father of Western medicine, prescribed oxymels for a wide variety of health concerns.”“Honey and vinegar have amazing health benefits just on their own. And when you combine them, it adds a lot of additional benefits.”“The source of where the honey comes from really matters.”“‘I've noticed in my own garden that bees are really drawn to the medicinal herbs.”“There was something like really magical about harvesting elderberries for the first time.”"It's okay to start small."“We're still manufacturing everything that we sell.”“Just doggedly pursuing it if you really believe in it. Not giving up and continuing to work at it is really the only way you're gonna get there or get anywhere.”"A better world is one that is holistic where all things, even the tiny unseen things, are thriving.”Links:Promo Code: BRANDSFORABETTERWORLD15% off on all oxymel honey tonics, sprays, and skin care from our online shop! www.mickelberrygardens.com…Madelyn Morris on LinkedIn - https://www.linkedin.com/in/madelyn-morris-86642819/Mickelberry Gardens - https://mickelberrygardens.com/ Mickelberry Gardens on LinkedIn - https://www.linkedin.com/company/mickelberry-gardens/Mickelberry Gardens on Facebook - https://www.facebook.com/MickelberryGardens/Mickelberry Gardens on Instagram - https://www.instagram.com/mickelberrygardens/Mickelberry Gardens on YouTube - https://www.youtube.com/@mickelberrygardens2593…Changing Your Mind by Michael Pollan (Book) - https://michaelpollan.com/books/how-to-change-your-mind/…Brands for a Better World Episode Archive - http://brandsforabetterworld.com/Brands for a Better World on LinkedIn - https://www.linkedin.com/company/brand-for-a-better-world/Modern Species - https://modernspecies.com/Modern Species on LinkedIn - https://www.linkedin.com/company/modern-species/Gage Mitchell on LinkedIn - https://www.linkedin.com/in/gagemitchell/…Print Magazine Design Podcasts - https://www.printmag.com/categories/printcast/…Heritage Radio Network - https://heritageradionetwork.org/Heritage Radio Network on LinkedIn - https://www.linkedin.com/company/heritage-radio-network/posts/Heritage Radio Network on Facebook - https://www.facebook.com/HeritageRadioNetworkHeritage Radio Network on X - https://x.com/Heritage_RadioHeritage Radio Network on Instagram - https://www.instagram.com/heritage_radio/Heritage Radio Network on Youtube - https://www.youtube.com/@heritage_radioChapters:03:00 Introduction to Mickelberry Gardens06:09 Understanding Oxymels: The Sweet and Sour Remedy09:02 Product Offerings: Exploring Unique Formulations11:46 Transitioning from Pharmaceuticals to Natural Remedies14:51 The Journey of Starting a Business17:37 The Importance of Local and Organic Sourcing20:55 The Health Benefits of Honey and Its Sources23:59 Lessons Learned in Business Growth26:43 Reflections on Business Strategy and Growth33:56 The Evolution of Business Growth35:45 Current Operations and Challenges38:23 The Importance of Delegation41:37 Manufacturing Control and Revenue Streams43:51 Becoming B Corp Certified47:47 Advice for Aspiring Entrepreneurs53:44 Personal Insights and RecommendationsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Best of Columbia On Demand
Jessica Rosenthal talks pharmaceuticals

Best of Columbia On Demand

Play Episode Listen Later Dec 19, 2025 13:14


12-19-2025: Wake Up Missouri with Randy Tobler, Stephanie Bell, and Producer Drake

The 'X' Zone Radio Show
Rob McConnell Interviews - DAVID TIPPIE - Collapse of Drugs

The 'X' Zone Radio Show

Play Episode Listen Later Dec 19, 2025 41:30 Transcription Available


David Tippie is a researcher and social commentator who examines the rapidly shifting landscape of modern medicine and pharmaceuticals in Collapse of Drugs. In this work, Tippie explores how economic pressures, regulatory failures, overprescription, and the growing influence of corporate interests have contributed to a system increasingly strained by addiction crises, drug shortages, and public mistrust. He also considers the rise of alternative approaches to health and wellness as a response to these failures, questioning whether the traditional pharmaceutical model is sustainable in its current form. Tippie's analysis challenges listeners and readers to rethink how societies define treatment, healing, and responsibility in an era of medical uncertainty.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-x-zone-radio-tv-show--1078348/support.Please note that all XZBN radio and/or television shows are Copyright © REL-MAR McConnell Meda Company, Niagara, Ontario, Canada – www.rel-mar.com. For more Episodes of this show and all shows produced, broadcasted and syndicated from REL-MAR McConell Media Company and The 'X' Zone Broadcast Network and the 'X' Zone TV Channell, visit www.xzbn.net. For programming, distribution, and syndication inquiries, email programming@xzbn.net.We are proud to announce the we have launched TWATNews.com, launched in August 2025.TWATNews.com is an independent online news platform dedicated to uncovering the truth about Donald Trump and his ongoing influence in politics, business, and society. Unlike mainstream outlets that often sanitize, soften, or ignore stories that challenge Trump and his allies, TWATNews digs deeper to deliver hard-hitting articles, investigative features, and sharp commentary that mainstream media won't touch.These are stories and articles that you will not read anywhere else.Our mission is simple: to expose corruption, lies, and authoritarian tendencies while giving voice to the perspectives and evidence that are often marginalized or buried by corporate-controlled media

OffScrip with Matthew Zachary

Dr. Marissa Russo trained to become a cancer biologist. She spent four years studying one of the deadliest brain tumors in adults and built her entire research career around a simple, urgent goal: open her own lab and improve the odds for patients with almost no shot at survival. In 2024 she applied for an F31 diversity grant through the NIH. The reviewers liked her work. Her resubmission was strong. Then the grant system started glitching. Dates vanished. Study sections disappeared. Emails went silent. When she finally reached a program officer, the message was clear: scrub the DEI language, withdraw, and resubmit. She rewrote the application in ten days. It failed. She had to start over. Again. This time with her identity erased.Marissa left the lab. She found new purpose as a science communicator, working at STAT News through the AAAS Mass Media Fellowship. Her story captures what happens when talent collides with institutional sabotage. Not every scientist gets to choose a Plan B. She made hers count.RELATED LINKSMarissa Russo at STAT NewsNIH F31 grant story in STATAAAS Mass Media FellowshipContact Marissa RussoFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Raise the Line
Helping People Understand Science Using the Science of Information: Jessica Malaty Rivera, Senior Science Communication Adviser at de Beaumont Foundation

Raise the Line

Play Episode Listen Later Dec 18, 2025 26:57


“People are not looking for a perfect, polished answer. They're looking for a human to speak to them like a human,” says Jessica Malaty Rivera, an infectious disease epidemiologist and one of the most trusted science communicators in the U.S. to emerge from the COVID-19 pandemic. That philosophy explains her relatable, judgement-free approach to communications which aims to make science more human, more accessible and less institutional. In this wide-ranging Raise the Line discussion, host Lindsey Smith taps Rivera's expertise on how to elevate science understanding, build public trust, and equip people to recognize disinformation. She is also keen to help people understand the nuances of misinformation -- which she is careful to define – and the emotional drivers behind it in order to contain the “infodemics” that complicate battling epidemics and other public health threats. It's a thoughtful call to educate the general public about the science of information as well as the science behind medicine. Tune in for Rivera's take on the promise and peril of AI-generated content, why clinicians should see communication as part of their professional responsibility, and how to prepare children to navigate an increasingly complex information ecosystem.Mentioned in this episode:de Beaumont Foundation If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

Oral Arguments for the Court of Appeals for the D.C. Circuit
Servier Pharmaceuticals LLC v. Robert F. Kennedy, Jr.

Oral Arguments for the Court of Appeals for the D.C. Circuit

Play Episode Listen Later Dec 18, 2025 72:50


Servier Pharmaceuticals LLC v. Robert F. Kennedy, Jr.

OffScrip with Matthew Zachary
Otherwise Healthy with Scott Capozza

OffScrip with Matthew Zachary

Play Episode Listen Later Dec 16, 2025 37:36


Scott Capozza and I could have been cloned in a bad lab experiment. Both diagnosed with cancer in our early twenties. Both raised on dial-up and mixtapes. Both now boy-girl twin dads with speech-therapist wives and a lifelong grudge against insurance companies. Scott is the first and only full-time oncology physical therapist at Yale New Haven Health, which means if he catches a cold, cancer rehab in Connecticut flatlines. He's part of a small, stubborn tribe of providers who believe movement belongs in cancer care, not just after it. We talked about sperm banking in the nineties, marathon training during chemo, and what it means to be told you're “otherwise healthy” when your lungs, ears, and fertility disagree. Scott's proof that survivorship is not a finish line. It's an endurance event with no medals, just perspective.RELATED LINKSScott Capozza on LinkedIn: https://www.linkedin.com/in/scott-capozza-a68873257Yale New Haven Health: https://www.ynhh.orgExercising Through Cancer: https://www.exercisingthroughcancer.com/team/scott-capozza-pt-msptProfiles in Survivorship – Yale Medicine: https://medicine.yale.edu/news-article/profiles-in-survivorship-scott-capozzaFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Tudor Dixon Podcast
The Tudor Dixon Podcast: Ozempic, Obesity & the Body Image Crisis: Aimee Donnellan Breaks Down the Truth

The Tudor Dixon Podcast

Play Episode Listen Later Dec 12, 2025 37:42 Transcription Available


In this eye-opening episode of The Tudor Dixon Podcast, Tudor sits down with author Aimee Donnellan for a deep dive into the meteoric rise of Ozempic—the diabetes drug turned cultural phenomenon for weight loss. Together, they unpack the surprising science behind GLP-1 medications, the growing trend of microdosing, and the real risks users often overlook. Donnellan and Dixon explore how body image pressures, diet culture, and the powerful food industry fuel America’s obesity crisis. They also discuss why the drug has become both celebrated and controversial, and what its popularity means for the future of weight management.See omnystudio.com/listener for privacy information.

Raise the Line
Aligning Investment in Family Medicine With Its Impact: Dr. Jen Brull, Board Chair of the American Academy of Family Physicians

Raise the Line

Play Episode Listen Later Dec 11, 2025 19:42


“Delivering a baby one day and holding a patient's hand at the end of life literally the next day...that continuity is very powerful,” says Dr. Jen Brull, board chair of the American Academy of Family Physicians (AAFP). And as she points out, that continuity also builds trust with patients, an increasingly valuable commodity when faith in medicine and science is declining. As you might expect given her role, Dr. Brull believes strengthening family medicine is the key to improving health and healthcare. Exactly how to do that is at the heart of her conversation with host Lindsey Smith on this episode of Raise the Line, which covers ideas for payment reform, reducing administrative burdens, and stronger support for physician well-being. And with a projected shortage of nearly forty thousand primary care physicians, Dr. Brull also shares details on AAFP's “Be There First” initiative which is designed to attract service-minded medical students – whom she describes as family physicians at heart -- early in their educational journey. “I have great hope that increasing the number of these service-first medical students will fill part of this gap.”Tune-in for an informative look at a cornerstone of the healthcare system and what it means to communities of all sizes throughout the nation.  Mentioned in this episode:AAFP If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

Oral Arguments for the Court of Appeals for the D.C. Circuit
Norwich Pharmaceuticals, Inc. v. Robert F. Kennedy Jr.

Oral Arguments for the Court of Appeals for the D.C. Circuit

Play Episode Listen Later Dec 11, 2025 56:11


Norwich Pharmaceuticals, Inc. v. Robert F. Kennedy Jr.

Oral Arguments for the Court of Appeals for the D.C. Circuit
Norwich Pharmaceuticals, Inc. v. Robert F. Kennedy, Jr.

Oral Arguments for the Court of Appeals for the D.C. Circuit

Play Episode Listen Later Dec 11, 2025 65:53


Norwich Pharmaceuticals, Inc. v. Robert F. Kennedy, Jr.

Mission Matters Podcast with Adam Torres
How Phio Pharmaceuticals Is Reawakening the Immune System to Fight Cancer

Mission Matters Podcast with Adam Torres

Play Episode Listen Later Dec 10, 2025 28:13


As part of our official DealFlow Discovery Conference Interview Series, produced by Mission Matters, along with our partner DealFlow Events, we're showcasing the innovative companies presenting at the DealFlow Discovery Conference and the executives behind them. Today's spotlight features Robert Bitterman, CEO & President of Phio Pharmaceuticals, who discusses how the company's INTASYL™ RNA platform is engineered to reactivate immune cells directly within the tumor microenvironment — opening the door to safer, more targeted cancer therapies. In this episode, Adam Torres interviews Robert Bitterman, CEO and President of Phio Pharmaceuticals, about the company's mission to create new pathways toward a cancer-free future. Robert explains how Phio's INTASYL™ platform uses targeted RNA technology to reactivate immune cells inside the tumor microenvironment, potentially offering a safer and more effective approach to treating cutaneous squamous cell carcinoma. He also shares early clinical data, the next steps toward pivotal trials, and why education and innovation remain at the heart of Phio's work. Follow Adam on Instagram at https://www.instagram.com/askadamtorres/ for up to date information on book releases and tour schedule. Apply to be a guest on our podcast: https://missionmatters.lpages.co/podcastguest/ Visit our website: https://missionmatters.com/ More FREE content from Mission Matters here: https://linktr.ee/missionmattersmedia Learn more about your ad choices. Visit podcastchoices.com/adchoices

Empowered Patient Podcast
Targeting Elevated Cortisol Seen as a Hidden Driver of Treatment-Resistant Type 2 Diabetes with Robert Jacks Sparrow Pharmaceuticals TRANSCRIPT

Empowered Patient Podcast

Play Episode Listen Later Dec 10, 2025


Robert Jacks, President and CEO of Sparrow Pharmaceuticals, identifies that an elevated cortisol level is a newly recognized cause of treatment-resistant type 2 diabetes. A significant portion of patients with diabetes who do not respond to standard treatments, including GLP-1 agonists, have underlying high cortisol. Sparrow has developed a drug designed to lower cortisol levels inside cells, directly addressing the underlying driver of the disease, and to be used as a complement to existing treatments. This concept of targeting cortisol-driven resistance could be extended to other conditions, such as treatment-resistant hypertension. Robert explains, "I feel as though Sparrow has come full circle, actually, with the mechanism of our drug. Originally, we have a drug that targets HSD-1. We can talk about what that is, but it's involved in intracellular cortisol regulation. This was a class of drugs that was originally developed targeting cardiometabolic diseases like type 2 diabetes. And the drugs had some moderate efficacy, but they weren't well differentiated in a broad population and largely were just discontinued for commercial reasons." "Our company was founded a number of years ago based on the idea that these drugs had real potential but hadn't been used in the right patient population. And that being the patient population with the disease that we know is driven by excess cortisol toxicity, because that's aligned with the mechanism, as I was mentioning. So we generated some really interesting data in a rare disease called Endogenous Cushing syndrome. This is a very severe orphan disease with patients who have very severely elevated cortisol, showing in fact that yes, this mechanism does seem like it could have a very major impact in the right patient population." "Simultaneously, another company published some data showing that actually there's a very large population of people with treatment-resistant type 2 diabetes, a very high level of medical need, and that their underlying disease actually is being driven by elevated levels of cortisol. And so when you bring together the data that we generated and what appears to be a large amount needed in a large population, it seems like we may have the perfect solution for that. So we've refocused our efforts on a broad population of treatment-resistant type 2 diabetes in patients whose disease is being impacted or driven by elevated cortisol levels."  #SparrowPharmaceuticals #Type2Diabetes #CardiometabolicDisease #CortisolRegulation #Cortisol #GLP1 #RareDisease sparrowpharma.com  Listen to the podcast here

Empowered Patient Podcast
Targeting Elevated Cortisol Seen as a Hidden Driver of Treatment-Resistant Type 2 Diabetes with Robert Jacks Sparrow Pharmaceuticals

Empowered Patient Podcast

Play Episode Listen Later Dec 10, 2025 19:13


Robert Jacks, President and CEO of Sparrow Pharmaceuticals, identifies that an elevated cortisol level is a newly recognized cause of treatment-resistant type 2 diabetes. A significant portion of patients with diabetes who do not respond to standard treatments, including GLP-1 agonists, have underlying high cortisol. Sparrow has developed a drug designed to lower cortisol levels inside cells, directly addressing the underlying driver of the disease, and to be used as a complement to existing treatments. This concept of targeting cortisol-driven resistance could be extended to other conditions, such as treatment-resistant hypertension. Robert explains, "I feel as though Sparrow has come full circle, actually, with the mechanism of our drug. Originally, we have a drug that targets HSD-1. We can talk about what that is, but it's involved in intracellular cortisol regulation. This was a class of drugs that was originally developed targeting cardiometabolic diseases like type 2 diabetes. And the drugs had some moderate efficacy, but they weren't well differentiated in a broad population and largely were just discontinued for commercial reasons." "Our company was founded a number of years ago based on the idea that these drugs had real potential but hadn't been used in the right patient population. And that being the patient population with the disease that we know is driven by excess cortisol toxicity, because that's aligned with the mechanism, as I was mentioning. So we generated some really interesting data in a rare disease called Endogenous Cushing syndrome. This is a very severe orphan disease with patients who have very severely elevated cortisol, showing in fact that yes, this mechanism does seem like it could have a very major impact in the right patient population." "Simultaneously, another company published some data showing that actually there's a very large population of people with treatment-resistant type 2 diabetes, a very high level of medical need, and that their underlying disease actually is being driven by elevated levels of cortisol. And so when you bring together the data that we generated and what appears to be a large amount needed in a large population, it seems like we may have the perfect solution for that. So we've refocused our efforts on a broad population of treatment-resistant type 2 diabetes in patients whose disease is being impacted or driven by elevated cortisol levels."  #SparrowPharmaceuticals #Type2Diabetes #CardiometabolicDisease #CortisolRegulation #Cortisol #GLP1 #RareDisease sparrowpharma.com Download the transcript here

OffScrip with Matthew Zachary
Doctor No More: MaryAnn Wilbur

OffScrip with Matthew Zachary

Play Episode Listen Later Dec 9, 2025 40:31


Dr. MaryAnn Wilbur trained her whole life to care for patients, then left medicine behind when it became a machine that punished empathy and rewarded throughput. She didn't burn out. She got out. A gynecologic oncologist, public health researcher, and no-bullshit single mom, MaryAnn walked straight off the cliff her career breadcrumbed her to—and lived to write the book.In this episode, we talk about what happens when doctors are forced to choose between their ethics and their employment, why medicine now operates like a low-resource war zone, and how the system breaks the very people it claims to elevate. We cover moral injury, medical gaslighting, and why she refused to lie on surgical charts just to boost hospital revenue.Her escape plan? Tell the truth, organize the exodus, and build something that actually works. If you've ever wondered why your doctor disappeared, this is your answer. If you're a clinician hiding your own suffering, this is your permission slip.RELATED LINKSMaryAnn Wilbur on LinkedInMedicine ForwardClinician Burnout FoundationThe Doctor Is No Longer In (Book)Suck It Up, Buttercup (Documentary)FEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

340B Insight
States Expand 340B Reporting Requirements

340B Insight

Play Episode Listen Later Dec 9, 2025 18:53


340B Insight wants to make our podcast the best it can be. To help us succeed, we'd like to hear your thoughts. Please take just a few minutes to complete our listener survey, and we will enter you in a drawing to win a $100 gift card! To participate, please go to 340bpodcast.org/survey.Some of the most consequential changes for 340B this year came not from Washington D.C., but from statehouses across the country. We speak with Tom O'Donnell, senior vice president of government relations at 340B Health, to recap some of the biggest changes on the state legislative level throughout this year and to preview what might come from the states in 2026.Seven States Enact New Reporting LawsThis year, Colorado, Hawaii, Idaho, Indiana, Ohio, Rhode Island, and Vermont have added new 340B reporting laws, increasing the list of states with such mandates to 10. O'Donnell says the first reporting requirements that Minnesota enacted in 2023 have influenced newer requirements in the other states. He notes hospitals' continuing concerns about the burdens and possible repercussions of focusing on several specific types of reporting data, including breakdowns by payer type and most frequently used drugs.Hybrid Bills Combine Protections With Reporting MandatesFive states that passed new 340B laws in 2025 did so with a twist. Colorado, Hawaii, Maine, Rhode Island, and Vermont passed combination bills with both contract pharmacy protections with new reporting mandates. O'Donnell says he's also concerned that statehouses are shoehorning in amendments to original statutes to ramp up concerning reporting requirements.Model Legislation Could Mean More Debate in 2026While Minnesota has served as a reference for reporting mandates for other states, model legislation from the American Legislative Exchange Council (ALEC) has created more opportunities for state legislators to push proposals that would limit or scrutinize 340B. O'Donnell says this reflects part of the latest efforts from drugmakers to take their 340B priorities to sympathetic lawmakers at the state level, and it underscores the importance of informing and supporting hospitals on how to push back against these bills.Resources:HRSA Approves Novartis's 340B Rebate Pilot ProposalState Policy & Advocacy Communications Resource Center

Empowered Patient Podcast
Targeting Macrophages Instead of T Cells to Overcome Treatment-Resistant Cancers with Dr. Petri Bono Faron Pharmaceuticals TRANSCRIPT

Empowered Patient Podcast

Play Episode Listen Later Dec 8, 2025


Dr. Petri Bono, Chief Medical Officer at Faron Pharmaceuticals, describes the development of bexmarilimad, a novel first-in-class immunotherapy that, unlike existing checkpoint inhibitors targeting T cells, targets the Clever 1 receptor on macrophages. This treatment is designed to reprogram the tumor microenvironment by switching marcophages from suppressive to active, enabling the patient's immune system to recognize and attack cancer cells. The primary disease target is higher-risk Myelodysplastic syndromes because the cancer cells in virtually all MDS patients express the Clever 1 target. Petri explains, "We are developing a completely new type of treatment. Currently, cancer patients are treated with immunotherapies called checkpoint inhibitors that target immune checkpoints. But our approach is targeting completely different cells, not T cells, but rather macrophages. And that's why we are first in class with a novel mode of action. And that's why it's important that these macrophages are shown to, for example, contribute to treatment resistance in many tumors." "Clever 1 actually is a receptor that was identified about 20 years ago. It found a certain macrophage as well as myeloid cells. And Clever 1 keeps the immune system in a tolerant and suppressive state. In cancer, for example, these Clever 1-positive macrophages essentially help the malignancy grow instead of helping to fight against it. And then our approach is that we want to block Clever 1 with our monoclonal antibody, bexmarilimab. So those macrophages switch the phenotype into an active antigen, preventing a pro-inflammatory state, and this reawakens immune surveillance. It allows T cells in the system to actually recognize the malignant cells themselves as dangerous and mount a proper antitumor response. So, a completely new mode of action by targeting Clever 1, we are not just adding another cytotoxic mechanism. We are removing the immune break and enabling the patient's own immune system to do the job that it was originally designed to do."  #FaronPharmaceuticals #BloodCancer #MDS #MyelodysplasticSyndrome #HR-MDS #CancerResearch #novelimmunotherapy #Bexmarilimab #Clever1 faron.com Listen to the podcast here

Empowered Patient Podcast
Targeting Macrophages Instead of T Cells to Overcome Treatment-Resistant Cancers with Dr. Petri Bono Faron Pharmaceuticals

Empowered Patient Podcast

Play Episode Listen Later Dec 8, 2025 20:57


Dr. Petri Bono, Chief Medical Officer at Faron Pharmaceuticals, describes the development of bexmarilimad, a novel first-in-class immunotherapy that, unlike existing checkpoint inhibitors targeting T cells, targets the Clever 1 receptor on macrophages. This treatment is designed to reprogram the tumor microenvironment by switching marcophages from suppressive to active, enabling the patient's immune system to recognize and attack cancer cells. The primary disease target is higher-risk Myelodysplastic syndromes because the cancer cells in virtually all MDS patients express the Clever 1 target. Petri explains, "We are developing a completely new type of treatment. Currently, cancer patients are treated with immunotherapies called checkpoint inhibitors that target immune checkpoints. But our approach is targeting completely different cells, not T cells, but rather macrophages. And that's why we are first in class with a novel mode of action. And that's why it's important that these macrophages are shown to, for example, contribute to treatment resistance in many tumors." "Clever 1 actually is a receptor that was identified about 20 years ago. It found a certain macrophage as well as myeloid cells. And Clever 1 keeps the immune system in a tolerant and suppressive state. In cancer, for example, these Clever 1-positive macrophages essentially help the malignancy grow instead of helping to fight against it. And then our approach is that we want to block Clever 1 with our monoclonal antibody, bexmarilimab. So those macrophages switch the phenotype into an active antigen, preventing a pro-inflammatory state, and this reawakens immune surveillance. It allows T cells in the system to actually recognize the malignant cells themselves as dangerous and mount a proper antitumor response. So, a completely new mode of action by targeting Clever 1, we are not just adding another cytotoxic mechanism. We are removing the immune break and enabling the patient's own immune system to do the job that it was originally designed to do."  #FaronPharmaceuticals #BloodCancer #MDS #MyelodysplasticSyndrome #HR-MDS #CancerResearch #novelimmunotherapy #Bexmarilimab #Clever1 faron.com Download the transcript here

Free Birth Society
Death of the Maiden: Raquel's Journey into Motherhood at 39

Free Birth Society

Play Episode Listen Later Dec 5, 2025 65:02


This week, Emilee is joined by Raquel, who shares her extraordinary first pregnancy and sovereign birth at the age of 39.Raquel speaks candidly about the profound transitions she navigated during this time. The death of her mother, leaving her job, moving homes, and entering into the work of congruency, boundaries, and privacy. Choosing a wild pregnancy, she hired a Radical Birth Keeper graduate to hold space as she walked this sacred path.She opens up about the challenges she faced postpartum with nursing and her child's tongue tie, reflecting on what she might do differently now. And she speaks with clarity about her sense of completion after one child, naming that she does not desire more.This conversation carries the archetype of the death of the maiden, a story of initiation, sovereignty, and the power of claiming motherhood on one's own terms.Donate to the podcast here. If you want to connect with Raquel, follow her on Instagram here and you can find her website here.Find more from Emilee on Instagram, YouTube and the Free Birth Society website.Disclaimer: Free Birth Society, LLC of North Carolina shares personal and educational stories and experiences related to freebirth and holistic care. This content is not medical advice, and we are not a licensed midwifery practice. Testimonials reflect individual experiences; results may vary. For services or scheduling, contact info@freebirthsociety.com. See full disclaimer at freebirthsociety.com/youtubeterms.

OffScrip with Matthew Zachary
Standard Deviation EP5: Damage Done

OffScrip with Matthew Zachary

Play Episode Listen Later Dec 4, 2025 13:55


Episode 5 of Standard Deviation with Oliver Bogler on the Out of Patients podcast feed pulls you straight into the story of Dr Ethan Moitra, a psychologist who fights for LGBTQ mental health while the system throws every obstacle it can find at him.Ethan built a study that tracked how COVID 19 tore through an already vulnerable community. He secured an NIH grant. He built a team. He reached 180 participants. Then he opened an email on a Saturday and learned that Washington had erased his work with one sentence about taxpayer priorities. The funding vanished. The timeline collapsed. His team scattered. Participants who trusted him sat in limbo.A federal court eventually forced the government to reinstate the grant, but the damage stayed baked into the process. Ethan had to push through months of paperwork while his university kept the original deadline as if the shutdown had not happened. The system handed him a win that felt like a warning.I brought Ethan on because his story shows how politics reaches into science and punishes the people who serve communities already carrying too much trauma. His honesty lands hard because he names the fear now spreading across academia and how young scientists question whether they can afford to care about the wrong population.You will hear what this ordeal did to him, what it cost his team, and why he refuses to walk away.RELATED LINKSFaculty PageNIH Grant DetailsScientific PresentationBoston Globe CoverageFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Raise the Line
Reimagining Public Health: Dr. Deb Houry, Former Chief Medical Officer at Centers for Disease Control and Prevention

Raise the Line

Play Episode Listen Later Dec 4, 2025 16:27


“This is a time to reimagine public health and public health/healthcare system integration,” says Dr. Deb Houry, the former chief medical officer for the US Centers for Disease Control and Prevention. In this thoughtful Raise the Line conversation, Dr. Houry reflects on unprecedented federal action in vaccine guidance and other issues since her noteworthy resignation from the CDC in August, and sees a more decentralized landscape emerging where states and localities play a larger role in providing public health recommendations. And while she acknowledges upsides to this shift, she's also concerned what the absence of a national consensus on health standards could mean. “Diseases don't recognize borders, and it's also important that people have equitable access to preventative services, vaccines, and other things,” she tells host Lindsey Smith. Tune in for Dr. Houry's seasoned perspective on this consequential moment in public health, and her encouraging message for learners and early career providers considering a career in the sector.Mentioned in this episode:DH Leadership & Strategy Solutions If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

Radically Genuine Podcast
210. The Mental Health Psyop: How Fear and Pharmaceuticals Create Lifelong Dependence

Radically Genuine Podcast

Play Episode Listen Later Dec 4, 2025 70:02


Dr. Roger McFillin was interviewed by Renaud Beauchard from Tocsin Media—France's leading independent media platform with 30 million monthly views. In this unflinching conversation, Dr. Roger McFillin exposes what he calls a deliberate psychological operation on the American people: a system designed not to heal but to create lifelong customers, sever your connection to God, and make you dependent on medical authority for problems that were never diseases in the first place. The chemical imbalance theory? Born in pharmaceutical marketing rooms, not laboratories. ADHD? A label that stops investigation into the real causes poisoning our children. This isn't incompetence. It's an attack on human consciousness itself. And the first step to freedom is understanding exactly how they did it to you. Visit Center for Integrated Behavioral HealthDr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here

OffScrip with Matthew Zachary
The Good Cancer Club Sucks: Chelsea J. Smith

OffScrip with Matthew Zachary

Play Episode Listen Later Dec 2, 2025 45:46


Chelsea J. Smith walks into a studio and suddenly I feel like a smurf. She's six-foot-three of sharp humor, dancer's poise, and radioactive charm. A working actor and thyroid cancer survivor, Chelsea is the kind of guest who laughs while dropping truth bombs about what it means to be told you're “lucky” to have the “good cancer.” We talk about turning trauma into art, how Shakespeare saved her sanity during the pandemic, and why bartending might be the best acting class money can't buy. She drops the polite bullshit, dismantles survivor guilt with punchline precision, and reminds every listener that grace and rage can live in the same body. If you've ever been told to “walk it off” while your body betrayed you, this one hits close.RELATED LINKS• Chelsea J. Smith Website• Chelsea on Instagram• Chelsea on Backstage• Chelsea on YouTube• Cancer Hope Network• Artichokes and Grace – Book by Chelsea's motherFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

AP Audio Stories
UK and US agree zero-tariff deal on pharmaceuticals

AP Audio Stories

Play Episode Listen Later Dec 1, 2025 0:43


AP's Lisa Dwyer reports on a new deal between the U.S. and the U.K. over pharmaceuticals.

The Future of Everything presented by Stanford Engineering
Best of: How to take waste out of wastewater

The Future of Everything presented by Stanford Engineering

Play Episode Listen Later Nov 28, 2025 29:19


In October, chemical engineer Will Tarpeh was awarded a 2025 MacArthur “Genius Grant” in recognition of his pioneering work to turn wastewater into a source of valuable materials. Will envisions a future in which the concept of wastewater is obsolete, thanks to advances in recycling. A couple of years ago, we sat down to talk with him about this work, and we hope you'll take another listen today to learn more about the research Will is doing to transform the potential of wastewater into resources.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: ​​William Abraham TarpehConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces Will Tarpeh, a professor of chemical engineering at Stanford University.(00:03:01) Wastewater as a Modern MineHow elements like nitrogen and phosphorus can be recovered from waste.(00:04:15) Path to Sanitation ResearchWill shares what led to his interest in studying wastewater.(00:06:55) The Science of SeparationThe electrochemical and material techniques to extract valuable compounds.(00:08:37) Urine-Based FertilizerHow human urine could meet up to 30% of global fertilizer needs.(00:11:08) Drugs in WastewaterThe potential of reclaiming pharmaceuticals from waste streams.(00:14:14) Decentralized SanitationOpportunities for neighborhood or household-scale treatment systems.(00:16:48) Source Separation SystemsHow dividing waste at the source improves recycling and recovery.(00:18:56) Global Sanitation ChallengesWays that developing countries can adopt modern waste solutions.(00:23:51) Preventing Algal BloomsThe systems that are helping to reduce nutrient pollution and dead zones.(00:27:16) The Urine SummitA community advancing urine recycling and sustainable sanitation policy.(00:28:43) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

BYU-Idaho Radio
From Fangs to Pharmaceuticals: Venitox Labs Extracts Potent Venoms

BYU-Idaho Radio

Play Episode Listen Later Nov 26, 2025 2:51


Idaho Gems is a BYU-Idaho Radio series featuring locals making a large impact. In this interview with Natalia Dyer, Idaho Gem, Rob Clark, founder of Venitox, shares about breaking into the snake venom industry. He also reflects on his love for his snakes and the importance of his work.

OffScrip with Matthew Zachary
The Nicest Bus in Cancer: Julia Stalder

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 25, 2025 39:14


When Julia Stalder heard the words ductal carcinoma in situ, she was told she had the “best kind of breast cancer.” Which is like saying you got hit by the nicest bus. Julia's a lawyer turned mediator who now runs DCIS Understood, a new nonprofit born out of her own diagnosis. Instead of panicking and letting the system chew her up, she asked questions the industry would rather avoid. Why do women lose breasts for conditions that may never become invasive? Why is prostate cancer allowed patience while breast cancer gets the knife? We talked about doctors' fear of uncertainty, the epidemic of overtreatment, and what happens when you build a movement while still in the waiting room. Funny, fierce, unfiltered—this one sticks.RELATED LINKS• DCIS Understood• Stalder Mediation• Julia's story in CURE Today• PreludeDx DCISionRT feature• Julia on LinkedInFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

340B Insight
Special Mini-Episode: Listener Survey

340B Insight

Play Episode Listen Later Nov 24, 2025 3:13


In this special mini-episode, we invite listeners to help shape the future of the show and enter a drawing for a $100 gift card by participating in our first-ever listener survey. Since launching in May 2020, 340B Insight has released more than 125 episodes featuring conversations with hospital and health system leaders, policy experts, and operations specialists from across the country. Their insights have helped listeners stay informed on the latest developments in 340B and bring practical lessons back to their own organizations.As we plan the next phase of the podcast, we want to hear directly from our listeners. The brief survey asks what draws you to the show, the topics and guests you've found most valuable, and what you'd like us to explore in future episodes. Your input will help ensure the podcast continues to reflect the needs and interests of the 340B community.The survey takes only a few minutes to complete. You may submit your responses anonymously, or you can share your contact information to be entered into a drawing for a $100 gift card. Take the survey by visiting 340bpodcast.org/survey. Thank you for listening and sharing your thoughts!

CoROM cast. Wilderness, Austere, Remote and Resource-limited Medicine.
170-Guerrilla Garden for MSIW – Medicine

CoROM cast. Wilderness, Austere, Remote and Resource-limited Medicine.

Play Episode Listen Later Nov 21, 2025 41:11


This week, Aebhric OKelly and Sam Coffman continue their discussion on the Guerrilla Medic and what to grow in their garden to supplement their ICU. Sam discusses the unique advantages of herbal remedies in treating viral infections. They discuss easy-to-find herbal medicine from your camp kitchen.TakeawaysHerbs can address specific health niches that pharmaceuticals cannot.Herbal formulas are effective for various viral infections.Herbs can help repair and restore tissue health.The mucosa and lymph movement are supported by herbal remedies.Herbs can slow down and stop virus shedding.Pharmaceuticals lack the holistic approach that herbs provide.Herbs can enhance the body's terrain for better health.Herbal remedies can be more effective in certain health conditions.The use of herbs can lead to better overall health outcomes.Understanding the unique benefits of herbs is crucial for health.Chapters00:00 Introduction to Medicinal Herbs10:46 Key Herbs for Upper Respiratory Health14:10 Herbs for Gut and Liver Support17:42 Common Kitchen Herbs to Support your ICU26:56 Honey as Medicine31:26 More Kitchen Herbs35:44 Improvised Medicine Workshop at SOMSA

OffScrip with Matthew Zachary
Standard Deviation EP4: The Gamble

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 20, 2025 11:13


Dr. Rachel Gatlin entered neuroscience with curiosity and optimism. Then came chaos. She started her PhD at the University of Utah in March 2020—right as the world shut down. Her lab barely existed. Her advisor was on leave. Her project focused on isolation stress in mice, and then every human on earth became her control group. Rachel fought through supply shortages, grant freezes, and the brutal postdoc job market that treats scientists like disposable parts. When her first offer vanished under a hiring freeze, she doubled down, rewrote her plan, and won her own NIH training grant. Her story is about survival in the most literal sense—how to keep your brain intact when the system built to train you keeps collapsing.RELATED LINKS• Dr. Rachel Gatlin on LinkedIn• Dr. Gatlin's Paper Preprint• Dr. Eric Nestler on Wikipedia• News Coverage: Class of 2025 – PhD Students Redefine PrioritiesFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Raise the Line
The Power of Empathy in Science Communication: Dr. Jess Steier, Founder of Unbiased Science

Raise the Line

Play Episode Listen Later Nov 20, 2025 20:03


“My most powerful content is when I lead with my voice as a mom because I have the same concerns about keeping my kids safe as my audience does. It's a powerful and effective way to find common ground with people,” says Dr. Jess Steier, a popular public health scientist and science communicator seeking to bridge divides and foster trust through empathetic, evidence-based communication. Dr. Steier has several platforms from which to do this work, including  Unbiased Science --  a communication hub that uses multiple social media platforms and other communications channels to share validated health and science information -- and as executive director of the Science Literacy Lab, a nonprofit organization dedicated to reaching a diverse audience seeking clarity and reliable information on scientific topics. “The science is less than half the battle,” she explains. “It's about how to communicate with empathy.”Join Raise the Line host Lindsey Smith for a valuable conversation that explores:What sources Dr. Steier relies on to validate informationHow she uses “escape room” exercises to train clinicians on empathetic communicationWhy tailored, story-driven messages reach audiences more effectively than facts.Mentioned in this episode:Unbiased Science If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

OffScrip with Matthew Zachary
Reenactments, Rants, and Really F*cked Up Insurance

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 18, 2025 47:40


EPISODE DESCRIPTIONBefore she was raising millions to preserve fertility for cancer patients, Tracy Weiss was filming reenactments in her apartment for the Maury Povich Show using her grandmother's china. Her origin story includes Jerry Springer, cervical cancer, and a full-body allergic reaction to bullshit. Now, she's Executive Director of The Chick Mission, where she weaponizes sarcasm, spreadsheets, and the rage of every woman who's ever been told “you're fine” while actively bleeding out in a one-stall office bathroom.We get into all of it. The diagnosis. The misdiagnosis. The second opinion that saved her life. Why fertility preservation is still a luxury item. Why half of oncologists still don't mention it. And what it takes to turn permission to be pissed into a platform that actually pays for women's futures.This episode is blunt, hilarious, and very Jewish. There's chopped liver, Carrie Bradshaw slander, and more than one “fuck you” to the status quo. You've been warned.RELATED LINKSThe Chick MissionTracy Weiss on LinkedInFertility Preservation Interview (Dr. Aimee Podcast)Tracy's Story in Authority MagazineNBC DFW FeatureStork'd Podcast EpisodeNuDetroit ProfileChick Mission 2024 Gala RecapFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Free Birth Society
16. Kristin Hauser on Holistically Handling Excessive Bleeding at Home

Free Birth Society

Play Episode Listen Later Nov 14, 2025 80:54


This week, I'm joined once again by Kristin Hauser, a beloved and regular guest on the Free Birth Society Podcast. We weave through the stories of Kristin's four births, with a special focus on her most recent freebirth and the profound lessons it offered.Kristin shares the raw reality of experiencing excessive bleeding in her fourth birth, and how it initiated her into a new relationship with her blood and her body. For the first time in her mothering journey, she was required to stay in bed and truly receive care, nourishment, and love from the women around her.In this conversation, Kristin reflects on how birth taught her not only resilience but also the art of receiving. Her story is a powerful reminder of how important the web of support is for us during these sacred times. ✨ Join The Lighthouse — A private, life-changing membership space for conscious, sovereign women. Check it out here.✨Donate to the podcast here.If you want to connect with Kristin, follow her on Instagram here and you can find her website here. Enrollment for The Blood Mysteries School opens soon— and it is, truly, a life-changing experience for those ready to walk this path of remembrance. Join the waitlist here. Kristin's past Free Birth Society Podcast episodes:Season 1From An Easy Birth To A Challenging Postpartum: Kristin's Story - https://youtu.be/KHYHH-irHFg?si=wjwBvBb26EZaPgFJ Season 2Reflections of Kristin's Wild Pregnancy - https://youtu.be/WTJeDK-bs4g?si=It30ILHOfaxwoHKE Season 3Being Open To A New Story: The Wisdom of Kristin's Freebirth - https://youtu.be/C3IGhyqPepI?si=YO7n7QPl9D8AQ0nV Season 5The Blood Mysteries School with Kristin Hauser and Nancy Lucina - https://youtu.be/3ecIfsi5oxM?si=QmUCDN4IsZCZb43W Season 6Radical Womb Healing as a Path to Freebirth with Kristin Hauser - https://youtu.be/A4UlAIiG0Lk?si=7mIL4-6CO9ZwTWTPSeason 7Embodying the Priestess in Our Everyday Mundane Lives with Nancy Lucina and Kristin Hauser - https://youtu.be/rYrIrObMAtY?si=Ges57c7UiWLtDeIG Find more from Emilee on Instagram, YouTube and the Free Birth Society website.Disclaimer: Free Birth Society, LLC of North Carolina shares personal and educational stories and experiences related to freebirth and holistic care. This content is not medical advice, and we are not a licensed midwifery practice. Testimonials reflect individual experiences; results may vary. For services or scheduling, contact info@freebirthsociety.com. See full disclaimer at freebirthsociety.com/youtubeterms.

Raise the Line
Amplifying Physician Voices Online: Dr. Kevin Pho, Founder of KevinMD

Raise the Line

Play Episode Listen Later Nov 13, 2025 24:41


“I realized that rather than talking one-to-one with patients in the exam room, you could talk one-to-many on social media,” says Dr. Kevin Pho, explaining the origins of KevinMD, the highly influential information sharing site he created for physicians, medical students and patients twenty years ago. Since then, KevinMD has become a valuable space for clinicians and patients to share stories and perspectives on topics from burnout and moral injury to technology and trust. In this conversation with Raise the Line host Michael Carrese, Dr. Pho reflects on the dual paths that have defined his career: as a practicing internal medicine physician and as one of healthcare's most trusted online voices. And despite the challenges of doing so, Dr. Pho encourages other medical providers to follow his lead. “Patients are going online, and if physicians are not there, they're going to get information that's perhaps politically-driven or simply inaccurate.”This thoughtful conversation also explores: How social media has reshaped health communicationThe risks and rewards for clinicians of having an online presence Why medical schools should teach negotiating skillsMentioned in this episode:KevinMDEstablishing, Managing and Protecting Your Online Reputation If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

OffScrip with Matthew Zachary
Oy Vey! It's Libby Amber Shayo

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 11, 2025 45:17


EPISODE DESCRIPTION:Libby Amber Shayo didn't just survive the pandemic—she branded it. Armed with a bun, a New York accent, and enough generational trauma to sell out a two-drink-minimum crowd, she turned her Jewish mom impressions into the viral sensation known as Sheryl Cohen. What started as one-off TikToks became a career in full technicolor: stand-up, sketch, podcasting, and Jewish community building.We covered everything. Jew camp lore. COVID courtship. Hannah Montana. Holocaust comedy. Dating app postmortems. And the raw, relentless grief that comes with being Jewish online in 2025. Libby's alter ego lets her say the quiet parts out loud, but the real Libby? She's got receipts, range, and a righteous sense of purpose.If you're burnt out on algorithm-friendly “influencers,” meet a creator who actually stands for something. She doesn't flinch. She doesn't filter. And she damn well earned her platform.This is the most Jewish episode I've ever recorded. And yes, there will be guilt.RELATED LINKSLibby's Website: https://libbyambershayo.comInstagram: https://www.instagram.com/libbyambershayoTikTok: https://www.tiktok.com/@libbyambershayoLinkedIn: https://www.linkedin.com/in/libby-walkerSchmuckboys Podcast: https://jewishjournal.com/podcasts/schmuckboysForbes Feature: Modern Mrs. Maisel Vibes https://www.forbes.com/sites/joshweissMedium Profile: https://medium.com/@libbyambershayoFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform.For guest suggestions or sponsorship, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Raise the Line
Using Social Media to Rebuild Trust in Nutrition Science: Jessica Knurick, PhD, RDN

Raise the Line

Play Episode Listen Later Nov 11, 2025 24:06


“We've created this ecosystem where the vast majority of information on social media, particularly in nutrition science, is inaccurate or misleading,” says Dr. Jessica Knurick, a registered dietitian and Ph.D. in nutrition science specializing in chronic disease prevention. As you'll learn on this episode of Raise the Line with host Lindsey Smith, countering that trend has become Dr. Knurick's focus in the past several years, and her talent for translating complex scientific information into practical guidance has attracted a large following on social media. Beyond equipping her audience with the tools to think critically and make informed choices for themselves, she also wants them to make the connection between the generally poor health status of most Americans with public policies on food and health and advocate for more beneficial approaches. “We can create systems that put the most people in the position to succeed versus putting the most people in the position to fail.” Tune in to learn from this trusted voice on nutrition, food policy, and public health as she shares her perspectives on: Strategies for risk reduction and behavior changeWhat can rebuild trust in medical information How you can cut through the noise and spot misinformation onlineMentioned in this episode:Dr. Knurick's WebsiteTikTok ChannelInstagram FeedFacebook Page If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

Business Of Biotech
Funding Tips And Moving From R&D To Commercial With Madrigal Pharmaceuticals' Mardi Dier

Business Of Biotech

Play Episode Listen Later Nov 10, 2025 46:11 Transcription Available


We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Mardi Dier, CFO at Madrigal Pharmaceuticals, talks about building relationships in investment banking and investor relations before moving into business development and becoming a chief financial officer. Mardi describes how drug companies transition from an R&D focus to commercializing products, how to read IPO windows and manage expectations, pricing new drugs, and balancing commercial efforts with pipeline renewal and maintenance. Access this and hundreds of episodes of the Business of Biotech videocast under the Business of Biotech tab at lifescienceleader.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: ben.comer@lifescienceleader.comFind Ben Comer on LinkedIn: https://www.linkedin.com/in/bencomer/

340B Insight
How To Embed Clinical Pharmacists in Specialty Pharmacy

340B Insight

Play Episode Listen Later Nov 10, 2025 24:13


340B Insight wants to make our podcast the best it can be. To help us succeed, we'd like to hear your thoughts. Please take just a few minutes to complete our listener survey, and we will enter you in a drawing to win a $100 gift card! To participate, please go to 340bpodcast.org/survey.The large and growing field of specialty pharmacy means new opportunities and challenges for ensuring patients receive the specialty drugs they need and stay on the therapies that might save their lives. St. Luke's Health System, based in Boise, Idaho, has approached this mission by embedding clinical pharmacists in the specialty pharmacy space and using 340B as a critical tool. We speak with Josh Weber, senior director of ambulatory retail and specialty pharmacy services at St. Luke's, to learn more.How Clinical Pharmacists Can Be a “Value Multiplier”Embedding clinical pharmacists in their specialty pharmacies improves operations in myriad ways. These pharmacists can take the burden off other providers by meeting with patients to go over their drug regimens, coordinating care, and running split-fill programs to reduce waste. At St. Luke's, the approach has improved patient adherence to medications and reduced the time between the specialty prescription and the patient having the medication in hand to less than 48 hours – far quicker than the industry standard.340B Savings Are Key to the InvestmentWeber says cost savings from 340B are critical in calculating how they embed resources into specialty pharmacy, noting that improving adherence and retention can increase 340B savings exponentially. These savings then can enable health systems such as St. Luke's to reinvest in their internal specialty pharmacies, provide more patient cost assistance and unreimbursed care, and ultimately shield themselves from headwinds such as drugmaker contract pharmacy restrictions.Embedding Pharmacists Depends on Hospital-Specific FactorsFor hospitals considering following the lead of St. Luke's Health System, Weber said a variety of factors such as patient volume, payer mix, and drug spend can call for a variety of service models and investment strategies. Harnessing data such as heat maps showing where patients are and which clinics they visit can inform how best to embed pharmacists and ultimately improve specialty pharmacy care for patients.Resources:Drugmakers Release 340B Rebate Pilot Program DescriptionsHRSA 340B Rebate Model Pilot ProgramBeacon Rebate Model Resources

Free Birth Society
Mother of Nine: Radical Wisdom from Two Decades of Birth

Free Birth Society

Play Episode Listen Later Nov 7, 2025 56:55


After six births within the system—including a cesarean at 37 weeks due to partial placenta previa and subsequent hospital abuse—Ashleigh knew she was done.Now a mother of nine and a Radical Birth Keeper School graduate, Ashleigh joins me to share her accumulated wisdom from nearly twenty years of mothering and birthing. We met in person at Matriarch Rising Festival, and in this conversation, we explore what it means to truly live the lessons that birth offers us.We discuss the pros and cons of having children present during birth, what it looks like to honor our evolving faith journeys, and how Ashleigh navigated the tension between her freebirth path and her husband's discomfort with it.I also challenge Ashleigh's decision to pull away from her Christian audience, encouraging her to consider what it might mean to let her community see her more deeply. She speaks vulnerably about her own healing from rage and how she now coaches mothers who find themselves lashing out at their children—because she's been there too.Come listen, learn, and receive from a mother of nine whose story carries the depth and clarity only time, experience, and devotion can bring.✨Start Your Journey: The Complete Guide to Freebirth - Our best-selling, self-paced course for women ready to claim their births on their own terms. Enroll here.✨Donate to the podcast here. If you want to connect with Ashleigh, follow her on Instagram here. SPOTIFY/APPLE ONLY:Find more from Emilee on Instagram, YouTube and the Free Birth Society website.Disclaimer: Free Birth Society, LLC of North Carolina shares personal and educational stories and experiences related to freebirth and holistic care. This content is not medical advice, and we are not a licensed midwifery practice. Testimonials reflect individual experiences; results may vary. For services or scheduling, contact info@freebirthsociety.com. See full disclaimer at freebirthsociety.com/youtubeterms.

OffScrip with Matthew Zachary
Standard Deviation EP3: The Weight

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 6, 2025 14:56


When the system kills a $2.4 million study on Black maternal health with one Friday afternoon email, the message is loud and clear: stop asking questions that make power uncomfortable. Dr. Jaime Slaughter-Acey, an epidemiologist at UNC, built a groundbreaking project called LIFE-2 to uncover how racism and stress shape the biology of pregnancy. It was science rooted in community, humanity, and truth. Then NIH pulled the plug, calling her work “DEI.” Jaime didn't quit. She fought back, turning her grief into art and her outrage into action. This episode is about the cost of integrity, the politics of science, and what happens when researchers refuse to stay silent.RELATED LINKS• The Guardian article• NIH Grant• Jaime's LinkedIn Post• Jaime's Website• Faculty PageFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Raise the Line
What Restoring Extinct Species Means for Modern Medicine: Dr. Beth Shapiro, Chief Science Officer at Colossal Biosciences

Raise the Line

Play Episode Listen Later Nov 6, 2025 31:00


Could studying the DNA of extinct animals – or even bringing them back to life – help us save today's endangered species and inform modern medicine?  That may sound like the premise for a Hollywood movie, but it's work that our Raise the Line guest, Dr. Beth Shapiro, is actually engaged in as Chief Science Officer at Colossal Biosciences, which describes itself as the world's first and only de-extinction company.  “It's not just about learning about the past. It's learning about the past so we have more validated scientific information that we can use to predict what we can do to better influence the future,” she tells host Michael Carrese. An internationally-renowned evolutionary molecular biologist and paleogeneticist, Dr. Shapiro is a pioneer in ancient DNA research and has successfully sequenced genomes, like that of the dodo, to study evolution and the impact on humans. At Colossal Biosciences, she leads teams working to bring back traits of extinct species such as the mammoth, not for spectacle, but to restore ecological balance. “When species become extinct, you lose really fundamental interactions between species that existed in that ecosystem. By taking a species that's alive today and editing its DNA so that it resembles those extinct species, we can functionally replace those missing ecological interactions.” Tune into this utterly fascinating conversation to hear about what Jurassic Park got wrong, the positive ecological impact of reintroducing giant tortoises to Mauritius, and the ethics of using gene editing and other biotechnologies. Mentioned in this episode:Colossal Biosciences If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

C-Speak: The Language of Executives
Takeda Pharmaceuticals CEO Christophe Weber shares his unique leadership vision and global mission

C-Speak: The Language of Executives

Play Episode Listen Later Nov 6, 2025 20:58


In this episode of PNC C-Speak, Christophe Weber, president and CEO of Takeda Pharmaceuticals, discusses the company's global footprint and its mission to deliver life-transforming medicines worldwide.  Weber shares his leadership perspective, emphasizing the importance of cultural agility and value-driven operations.  “Our mission is to deliver life-transforming medicines. When we develop new medicines —  which is a very hard mission — we really aim for that medicine to be made available across the world for all patients,” Weber says. Listen to hear more about:-              Takeda's approach to ‘caring leadership' (4:33)-              How Takeda's corporate social responsibility program unites all employees (8:46)-              Where Takeda believes AI can make a difference (12:10)-              Why Takeda moved its headquarters to Massachusetts (15:00)Download a transcript of this episode.

OffScrip with Matthew Zachary
Stand By She: Allison Applebaum

OffScrip with Matthew Zachary

Play Episode Listen Later Nov 4, 2025 39:37


EPISODE DESCRIPTIONAllison Applebaum was supposed to become a concert pianist. She chose ballet instead. Then 9/11 hit, and she ran straight into a psych ward—on purpose. What followed was one of the most quietly revolutionary acts in modern medicine: founding the country's first mental health clinic for caregivers. Because the system had decided that if you love someone dying, you don't get care. You get to wait in the hallway.She's a clinical psychologist. A former dancer. A daughter who sat next to her dad—legendary arranger of Stand By Me—through every ER visit, hallway wait, and impossible choice. Now she's training hospitals across the country to finally treat caregivers like patients. With names. With needs. With billing codes.We talked about music, grief, psycho-oncology, the real cost of invisible labor, and why no one gives a shit about the person driving you to chemo. This one's for the ones in the waiting room.RELATED LINKSAllisonApplebaum.comStand By Me – The BookLinkedInInstagramThe Elbaum Family Center for Caregiving at Mount SinaiFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Raise the Line
Breaking Barriers to Leadership for Women in Medicine: Dr. Roopa Dhatt, Co-Founder of Women in Global Health

Raise the Line

Play Episode Listen Later Nov 4, 2025 34:28


According to the Bloomberg School of Public Health at Johns Hopkins University, women make up 70% of the global healthcare workforce but hold only about 25% of leadership positions. Our guest today on Raise the Line, Dr. Roopa Dhatt, has been a leading voice in the movement to correct that imbalance through co-founding an organization called Women in Global Health (WGH), which has established chapters in over 60 countries since it started a decade ago. Dr. Dhatt is also pursuing that agenda and addressing other pressing issues in healthcare as a Young Global Leader at the World Economic Forum. “We're changing the equation so women delivering health are also viewed and valued as leaders,” says the internal medicine physician and assistant professor at Georgetown University School of Medicine. Beyond leadership equity, Dr. Dhatt is also seeking to address systemic pay inequities and high levels of violence and harassment experienced by women in the health sector, issues that were highlighted in research conducted by WGH. Although WGH has seen high-level success influencing policy at the World Health Organization and United Nations, Dr. Dhatt says the heart of its success is local. “Women community health workers have begun to see themselves as leaders and the heroines of health in their communities. That's profound change.” Join host Michael Carrese for a probing conversation that identifies the structural barriers blocking advancement for women and that explains why the health of communities and the planet depend on inclusive leadership.Mentioned in this episode:Women in Global HealthWHO Report: Delivered By Women, Led By MenDr. Roopa Dhatt on LinkedIn If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

OffScrip with Matthew Zachary
Sick Days Not Included: Rebecca V. Nellis

OffScrip with Matthew Zachary

Play Episode Listen Later Oct 28, 2025 59:04


EPISODE DESCRIPTIONRebecca V. Nellis never meant to run a nonprofit. She just never left. Twenty years later, she's still helming Cancer and Careers after a Craigslist maternity-leave temp job turned into a lifelong mission.In this 60-minute doubleheader, we cover everything from theater nerdom and improv rules for surviving bureaucracy, to hanging up on Jon Bon Jovi, to navigating cancer while working—or working while surviving cancer. Same thing.Rebecca's path is part Second City, part Prague hostel, part Upper East Side grant writer, and somehow all of that makes perfect sense. She breaks down how theater kids become nonprofit lifers, how “sample sale feminism” helped shape a cancer rights org, and how you know when the work is finally worth staying for.Also: Cleavon Little. Tap Dance Kid. 42 countries. And one extremely awkward moment involving a room full of women's handbags and one very confused Matthew.If you've ever had to hide your diagnosis to keep a job—or wanted to burn the whole HR system down—this one's for you.RELATED LINKSCancer and CareersRebecca Nellis on LinkedIn2024 Cancer and Careers Research ReportWorking with Cancer Pledge (Publicis)CEW FoundationI'm Not Rappaport – Broadway InfoFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship opportunities, email podcast@matthewzachary.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Free Birth Society
Claiming It All: Celia's Story of Birth, Power, and Simplicity

Free Birth Society

Play Episode Listen Later Oct 24, 2025 71:39


This week, I am joined by Celia from the Bay Area, California, who shares her journey from birthing with medical midwives and working as a doula, to stepping fully into sovereign birth work and choosing freebirth with her fourth child.Born at home herself, Celia's path was forever changed when she read Portal and began to unravel everything she thought she knew about birth. As a graduate of the Radical Birth Keeper School, she now carries this work forward in her own community.Celia reflects on her four births, including the painful memory of her midwife pulling out her placentas. She shares how, in her fourth and most recent birth, allowing her placenta to be born in her own way and her own time became her favorite part of the entire experience.In this conversation, Celia names what it means to let birth be simple, to trust herself, and to claim it all.✨ Join The Lighthouse — A private, life-changing membership space for conscious, sovereign women. Check it out here.✨Donate to the podcast here. If you want to connect with Celia, follow her on Instagram here and find her website here. Find more from Emilee on Instagram, YouTube and the Free Birth Society website.Disclaimer: Free Birth Society, LLC of North Carolina shares personal and educational stories and experiences related to freebirth and holistic care. This content is not medical advice, and we are not a licensed midwifery practice. Testimonials reflect individual experiences; results may vary. For services or scheduling, contact info@freebirthsociety.com. See full disclaimer at freebirthsociety.com/youtubeterms.