Podcasts about Hacking

Most people spend their lives trying to outrun death instead of learning from it. This episode shows you why facing mortality directly can unlock resilience, forgiveness, gratitude, and peace while upgrading longevity, human performance, and even brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Suzanne O'Brien, RN—an end-of-life expert, hospice nurse, and founder of Doulagivers who has guided over 1,000 people through their final moments. She shares what the dying can teach the living about biohacking fear, letting go of unresolved trauma, and finding clarity before it's too late. Together they explore how hacking your mindset around death transforms not only emotional well-being but also physical health, neuroplasticity, and metabolism. You'll hear stories of people who discovered forgiveness and gratitude at the end of life, and how those practices directly influence mitochondria, sleep optimization, and longevity. They dive into the link between fear, stress chemistry, and chronic illness—and why tools like fasting, ketosis, cold therapy, supplements, nootropics, and functional medicine create the inner and outer resilience needed to face life fully. You'll Learn: • Why fear of death silently undermines health, performance, and human potential • How forgiveness and gratitude rewire neuroplasticity and boost brain optimization • What hospice nurses know about consciousness and near-death experiences that science is only starting to confirm • How unresolved trauma shows up as physical pain and disease at the end of life Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: fear of death, hospice nurse, doulagivers, end of life planning, good death, forgiveness practice, gratitude science, near death experience, hospice care stories, emotional trauma release, spiritual awakening, conscious dying, home funeral, palliative care, death doula training, legacy planning, end of life rituals, soul agreements, dying process stages, compassionate care Thank you to our sponsors! ECHO Water | Go to http://echowater.com/dave and use code DAVE10 for 10% off your ECHO Flask. Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. Resources: • Suzanne's Website: https://suzannebobrien.com/ • Get Suzanne's Book 'The Good Death': https://thegooddeathbook.com• Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:05 — Introduction 03:13 — End-of-Life Choices 09:50 — Forgiveness & Suffering 15:46 — Advice to Younger Self 20:00 — What Makes a Good Death 23:00 — Hospice Stories & Mystical Experiences 33:05 — The Good Death Defined 41:01 — Meaning & Purpose See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

More than 10 years in, journalists still have not figured out how to cover Trump. He understands the media environment better than a lot of reporters, and knows his outrageous acts and statements command attention—and that people will not be able to finish processing one outrage before the next one comes down the pike. But now he's laying down the terms of how he expects to be covered, and media orgs are complying by hiring or giving airtime to MAGA avatars. In the process, journalists are failing to hold the powerful to account. Plus, Dems actually went on offense and got their hands on the Epstein birthday book, and Israel is aggressively embracing the age of impunity. The Economist's James Bennet joins Tim Miller. show notes James, in The Economist, on his departure from the NYT over the Tom Cotton op-ed (gifted) James on the rules for defending democracy under Trump (gifted) Bulwark Live in DC and NYC at TheBulwark.com/events. Toronto is SOLD OUT

Major npm compromise A number of high-profile npm libraries were compromised after developers fell for a phishing email. This compromise affected libraries with a total of hundreds of millions of downloads a week. https://bsky.app/profile/bad-at-computer.bsky.social/post/3lydioq5swk2y https://github.com/orgs/community/discussions/172738 https://github.com/chalk/chalk/issues/656#issuecomment-3266894253 https://www.aikido.dev/blog/npm-debug-and-chalk-packages-compromised HTTP Request Signatures It looks like some search engines and AI bots are starting to use the HTTP request signature. This should make it easier to identify bot traffic. https://isc.sans.edu/diary/HTTP%20Request%20Signatures/32266

Full episode here: https://youtu.be/KnsCROZKTZA Join us on this episode of the Travis Makes Friends podcast as we dive deep with Pace Morby, a real estate powerhouse and community builder! From launching the world's largest real estate community in a Circle K parking lot to helping a homeless woman become a homeowner in just 20 days, Pace shares his journey, creative finance strategies, and why real estate remains the ultimate wealth-building vehicle. Discover how to navigate today's housing market, the power of in-person community, and the underrated potential of RV parks and co-living. Don't miss this inspiring conversation packed with actionable insights! Check out Pace's work at whereispace.com and tune in now! ✖️ ✖️ ✖️ ✖️

This week on Expert, Skin Therapist Tegan and co-host Sadaf are diving into one of 2025’s biggest beauty trends: hydration hacking. From electrolyte powders on your desk to “injectable moisturisers,” we’re breaking down what actually keeps your skin plump, dewy, and healthy – and what’s just clever marketing. We unpack: The difference between hydration, moisture, and barrier repair (and why it matters) Electrolyte powders, collagen blends, and injectables like Profhilo – are they worth it? The truth about hyaluronic acid, moisture sandwiching, and slugging Lifestyle factors you might be overlooking that leave skin parched In Win, Bin or Recycle, we debate baby powder after a shower. In Adore Anonymous, we answer a listener’s question about how many skincare steps you actually need (hint: it’s not ten). Everything mentioned: K18 HeatBounce Conditioning Heat Protectant SkinCeuticals HA Intensifier Vida Glow Pro Collagen + Sodii Everyday Hydration Salts - Tub - Unflavoured Vitadrop Rapid Hydration Sugar Free - 30 Serves Laneige Cream Skin Cerapeptide™ Whether you’re team serum, powder, or slugging, this episode will help you cut through the noise and get to the heart of what really hydrates skin. Credits: Hosts: Tegan Mac and Sadaf Razi Producer: Jasmine Riley For more beauty insights and exclusive offers, visit adorebeauty.com.au Disclaimer | Privacy Policy Adore Beauty acknowledges the Traditional Owners of the land on which we work and podcast. We pay our respects to Elders past, present and emerging.See omnystudio.com/listener for privacy information.

From YARA Offsets to Virtual Addresses Xavier explains how to convert offsets reported by YARA into offsets suitable for the use with debuggers. https://isc.sans.edu/diary/From%20YARA%20Offsets%20to%20Virtual%20Addresses/32262 Phishing via JavaScript in SVG Files Virustotal uncovered a Colombian phishing campaign that takes advantage of JavaScript in SVG files. https://blog.virustotal.com/2025/09/uncovering-colombian-malware-campaign.html FreePBX Patches FreePBX released details regarding two vulnerabilities patched last week. One of these vulnerabilities was already actively exploited. https://github.com/FreePBX/security-reporting/security/advisories/GHSA-3r47-p39v-vqqf

In this episode, I share news from my recent trip to the UK, noticing how it seems to have reached the epic proportions of a Black Mirror episode; from the absurd TV licensing program to the new Digital ID Brit cards that will track your behavior. I also explore how the UK may be serving as a testing ground for new levels of behavioral surveillance that could eventually spread globally. I dive into California's $900 “smart” license plates that track your every move, centralized government digital currencies, and my predictions for the next 20 years of Orwellian surveillance.Support the show on Patreon!In this week's episode:The UK's TV licensing system: Legal extortion through private contractorsThe Reviver R-plate: $900 to track yourself in California and ArizonaBrit Cards: UK's new “voluntary” Digital ID systemThe Bank of England's digital pound and programmable moneyHistorical patterns of control: From land ownership to neural interfacesWhy the UK is the blueprint for global surveillance rolloutPredictions for the next 20-50 years of biosurveillanceMatrix Community RoomsMatrix Community Space - https://matrix.to/#/#psysecure:matrix.orgIndividual Room Links:https://matrix.to/#/#lockdown-intro:matrix.orghttps://matrix.to/#/#lockdown-podcast:matrix.orghttps://matrix.to/#/#lockdown-general:matrix.orgShow Links:PsySecure ODSF Framework - https://odsf.psysecure.comLCD License Plate (not privacy friendly!) - https://reviver.com/rplate/Black Mirror S03E01 "Nosedive" - https://www.imdb.com/title/tt5497778/Bank of England's Digital Pound - https://www.bankofengland.co.uk/the-digital-poundBrit Card Digital ID System - https://www.labourtogether.uk/all-reports/britcardTV Licensing Detector Ads (1980s-90s): The Detector Van - https://www.youtube.com/watch?v=8NmdUcmLFkw"We know exactly where he is" - https://www.youtube.com/watch?v=qF3-S2sCnb8Keep One Eye Open - https://www.youtube.com/watch?v=mVfOmR7gAekMore Powerful Dector Vans! - https://www.youtube.com/watch?v=1Q9CsRRhWQI“One believes things because one has been conditioned to believe them.”- Mustapha Mond (Brave New World ★ Support this podcast on Patreon ★

Another example of the kind of kismet that happens when Jennifer and I meet up. We don't plan a guest list, we have Luana Anders, our moderator on the Flipside who does that for us. In this episode, the first person that comes through is Mr. Bailey, Luana's cat.  When Luana was on her death bed, her cat escaped from her house and disappeared. She called me in a panic. My soon to be wife Sherry went with me to see if we could find her. Sherry went into the backyard and said a prayer aloud: "Mr. Bailey, Luana needs you now." The cat appeared in the tree above, and jumped into Sherry's arms, a person she'd never met. Mr. Bailey wanted to talk about how animals have the ability to communicate to the afterlife, and while people may have filters on the brain that prevent them from that awareness, animals do not. Mr. Bailey confirmed what we've heard in the past; "animals understand how incarnation works, but humans do not." Hard for some folks to contemplate; dogs smell cancer, elephants can communicate over ten miles, octopuses have 9 brains, and do more with one year of life than humans can do in 90.  Some other pets stopped by to give their support. Then former President Reagan stopped by.  He said that our interview with JFK (a number of years ago, it's in the book BACKSTAGE PASS TO THE FLIPSIDE) inspired him to say hello.  He pointed out that he's had a number of lifetimes with Nancy in the past - even if he was married to someone else to begin with. (Jane Wyman whom Ronald said "raised him.")  I asked who in our classroom of notaries had invited him and he said it was John McCain. John came by some years ago after he passed to ask us to pass along a private message to his daughter, which I did through a producer at Coast to Coast radio.  I don't know if she dismissed the message, as I've yet to hear from her. But in those earlier conversations he confirmed a number of things only he could know - or be aware of.  People I interviewed in his office for the film "Three for the Road" and later, talked about meeting his victims of the Vietnam war on the flipside - and them understanding each other as players in a drama. He talked about the politics of the era when he passed, and this veiled reference to Steve Schmidt's 2020 comments about the current President were what I was referring to as someone had reposted them the other day. We've heard it often - people act out difficult roles onstage to get others to react and do that thing that they're supposed to do.  However, in terms of political debate, the former President deferred from doing so - as he put it "I just came by to express concern for how divide the country is." I asked if there was any advice he could give - some kind of grand gesture or action people could do. His answer was simple, yet profound. Smile.  Start smiling to people we know, then more that to people we don't know, then move that to people we may not like. Just the physical act of smiling changes the paradigm, and everyone can do that on their own. It sounds miniscule - but instead of arguing with someone who clearly still exists on the flipside, I think it's wise to consider that they're saying instead of belittling or berating it.  He was consider the great communicator - and why not listen to his advice. To be clear; we've communicated with a number of Presidents, both Bushes, Jimmy Carter, LBJ, Nixon, JFK, FDR and Truman.  Again - I ask the questions and Jennifer gives verbatim what she's hearing or sensing. It's possible miscommunicate, but when you've been working with someone weekly for ten years, if one is paying attention, we can see that these folks show up often to talk to us. And in this case - Ronnie himself.  While people may start with a defensive posture - defending him, or upset that he might speak on our podcast - the point is that anyone can invite him to have a conversation and see what he says. As noted, we have the current President's father and brother on a podcast, and the last President's late son Beau on that same podcast. It's mind bending to hear them talk about the play we're all involved in.  How we should spend more time talking to each other, coming together, than coming apart. Hard to fathom in today's climate, that that is the message that is repeated often. Enjoy. 

What if the foods you think are healthy are actually disrupting your biology? From sugar marketed as a performance tool to “whole grains” that drive cravings, this episode uncovers how hidden traps in modern nutrition can hijack your brain, wreck your metabolism, and accelerate aging. You'll learn how to rethink daily eating so it fuels energy, resilience, and long-term health instead of quietly sabotaging it. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Max Lugavere, health journalist, filmmaker, and bestselling author of Genius Foodsand The Genius Kitchen. Max is one of the most trusted voices in nutrition and functional medicine, translating complex science into practical tools you can use right now. His work has been featured on The Today Show, PBS, and across global media for helping people reclaim health through smarter food and lifestyle choices. In this re-run, Dave and Max break down the real impact of sugar, salt, and food processing on your brain and body. They explore how cooking methods change health outcomes, when fasting and ketosis become powerful tools, and why supplements, nootropics, and trace minerals fill gaps in the modern diet. They also tackle controversial topics like carnivore diets, cold therapy, and whether “healthy” plant-based foods are truly supporting resilience—or quietly eroding it. You'll Learn: • The biggest nutrition myths that silently damage health and performance • How sugar can act as both poison and fuel depending on context • Why cooking methods make the difference between nourishment and toxicity • The overlooked role of minerals, supplements, and culinary literacy • How nootropics, cold therapy, and sleep optimization reset your brain • Why some “health foods” accelerate aging instead of protecting you • The truth about carnivore diets, industrial farming, and sustainability • When fasting, ketosis, and carb cycling create optimal results This episode gives you a science-backed blueprint to hack your nutrition, sharpen your brain, and extend your longevity with foods that truly support your biology. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: uric acid longevity, uric acid metabolism, fructose uric acid pathway, xanthine oxidase inhibition, quercetin uric acid, luteolin supplements, AMP kinase uric acid, AMP deaminase metabolism, uric acid and mitochondria, uric acid and neuroplasticity, uric acid Alzheimer's risk, uric acid dementia prevention, uric acid and nitric oxide, fructose metabolism hibernation biology, evolutionary mismatch uricase mutation, fructokinase inhibition, uric acid and insulin resistance, gout biohacking, uric acid and obesity, uric acid functional medicine Resources: • Max's Website: https://www.maxlugavere.com/ • Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:30 — Introduction 1:51 — Resilience & Stress 2:41 — Food Philosophy 6:20 — Sugar & Metabolism 11:21 — Fructose & Flexibility 21:57 — Big Food & Morality 24:51 — Meat & Sustainability 26:30 — Cooking at Home 28:34 — Salt & Minerals 30:07 — Dietitians & Industry 32:45 — Intuitive Eating 41:13 — Cooking Risks 45:26 — Fish & Contaminants 49:16 — Lectins & Sensitivities 52:22 — Herbs & Spices 54:59 — Recipes & Highlights 58:17 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Unauthorized Issuance of Certificate for 1.1.1.1 Cloudflare published a blog post with more details regarding the bad 1.1.1.1 certificate that was issued by Fina. https://blog.cloudflare.com/unauthorized-issuance-of-certificates-for-1-1-1-1/ AI Model Namespace Reuse Deleted accounts on Huggingface can be taken over by other entities unrelated to the original owner. https://unit42.paloaltonetworks.com/model-namespace-reuse/ macOS vulnerability allowed Keychain and iOS app decryption without a password Excessive entitlements for the gcore binary facilitated access to key material that was sufficient to access secrets stored in Apple s keychain. https://www.helpnetsecurity.com/2025/09/04/macos-gcore-vulnerability-cve-2025-24204/

UL NO. 496: STANDARD EDITION | New Video on Building my Personal AI System, Anthropic Reveals One-person Hacking Company using Claude, Pentagon Says China Keeps Penetrating, and more... Read this episode online: https://newsletter.danielmiessler.com/p/ul-496 Personal AI Video I'm so excited about Subscribe to the newsletter at:https://danielmiessler.com/subscribe Join the UL community at:https://danielmiessler.com/upgrade Follow on X:https://x.com/danielmiessler Follow on LinkedIn:https://www.linkedin.com/in/danielmiesslerBecome a Member: https://danielmiessler.com/upgradeSee omnystudio.com/listener for privacy information.

Forget Mission: Impossible-style hacking - today's cyber crooks are all about manners. In this episode, we unravel how asking “pretty please” can crack open digital doors faster than any brute force attack. With tips, tales, and a touch of panic, we break down the importance of knowing your personal risk profile, locking down your accounts, and yes - finally turning on that MFA you've been ignoring. More info at HelpMeWithHIPAA.com/525

Most people think broccoli is a superfood, but the reality is more nuanced. In this episode of The Human Upgrade, Host Dave Asprey explores the good and bad of broccoli—why adult broccoli can block thyroid function and cause gut issues, while broccoli seeds deliver sulforaphane, the powerful compound that activates all three of your body's detox pathways. You'll learn how sulforaphane protects against glyphosate, repairs leaky gut, and upgrades mitochondria, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dave is joined by two Johns Hopkins–trained researchers whose expertise in biohacking, biochemistry, and functional medicine makes them trusted leaders in the field. Together they reveal how sulforaphane, berberine, curcumin, and alpha-lipoic acid outperform bulk vegetables and even rival GLP-1 weight loss drugs—delivering natural ways to improve metabolism, regulate dopamine, and protect the brain. Their research shows how targeted supplements can boost neuroplasticity, brain optimization, and human performance without the side effects of pharmaceuticals. Dave and his guests break down why bulk vegetables don't deliver enough beneficial compounds, how to hack plant toxins for maximum benefit, and why supplement stacks often outperform carnivore, vegan, or high-vegetable diets for long-term health. You'll discover how biohacking tools like fasting, ketosis, nootropics, cold therapy, and sleep optimization amplify these compounds for smarter not harder living. You'll Learn: • Why adult broccoli can disrupt thyroid function while broccoli seeds fuel detox and longevity • How sulforaphane, berberine, curcumin, and alpha-lipoic acid support metabolism and mitochondria • Why natural compounds can rival GLP-1 drugs for weight loss and energy regulation • The connection between glyphosate, leaky gut, inflammation, and brain fog • How to stack supplements with fasting, ketosis, and cold therapy for brain optimization • Why functional medicine and biohacking provide better long-term solutions than fad diets • The smarter not harder way to extract benefits from plants without the toxic load This episode is essential for anyone serious about biohacking, upgrading metabolism, extending longevity, and achieving high performance with resilience and clarity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: sulforaphane supplements, broccoli seed extract, detox pathways phase 1 2 3, NRF2 activation, glyphosate gut health, leaky gut repair biohacking, thyroid blockers broccoli, DIM I3C compounds, functional medicine detox, Johns Hopkins biohacking research, berberine metabolism, alpha lipoic acid mitochondria, curcumin weight loss, GLP-1 natural alternatives, dopamine metabolism regulation, neuroplasticity supplements, fasting and sulforaphane, ketosis and detox synergy, smarter not harder supplements, Dave Asprey broccoli Mara Labs Website: https://mara-labs.com/Dave for 28% off!Resources: -Mara Labs Website: https://mara-labs.com/Davefor 28% off!-BrocElite link: https://partnerships.mara-labs.com/4H6KD28/TZW7X/?&sub4=biohack&uid=123-GLPerfect link: https://partnerships.mara-labs.com/4H6KD28/TZW7X/?&sub4=biohack&uid=123Thank you to our sponsors! EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Mara Labs Website: NEED TO INSERT CODE • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:10 — Introduction 01:49 — Broccoli Benefits & Risks 09:24 — Plant Toxins & Modern Diet 12:56 — Mold Detox Experiences 18:30 — Mycotoxins, Glyphosate & Gut Health 26:20 — Metabolic Syndrome & Endotoxins 35:44 — Timing Sulforaphane for Glyphosate Protection 39:35 — Weight Loss & GL Perfect 49:19 — Personalization & Supplement Stacking 55:10 — Sleep, Ketosis & Berberine 58:30 — Alpha Lipoic Acid + Berberine Synergy 1:01:00 — Natural Alternatives to GLP-1 Drugs See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Exploit Attempts for Dassault DELMIA Apriso. CVE-2025-5086 Our honeypots detected attacks against the manufacturing management system DELMIA Apriso. The deserialization vulnerability was patched in June and is one of a few critical vulnerabilities patched in recent months. https://isc.sans.edu/diary/Exploit%20Attempts%20for%20Dassault%20DELMIA%20Apriso.%20CVE-2025-5086/32256 Android Bulletin Google released its September update, fixing two already-exploited privilege escalation flaws and some remote code execution issues. https://source.android.com/docs/security/bulletin/2025-09-01 Mis-issued Certificates for SAN iPAddress:1.1.1.1 by Fina RDC 2020 Certificate authority Fina RDC issues a certificate for Cloudflare s IP address 1.1.1.1 https://groups.google.com/a/mozilla.org/g/dev-security-policy/c/SgwC1QsEpvc

As artificial intelligence continues to evolve, new Texas laws are establishing a foundational framework for its governance, with a focus on the prevention of harm and ethical use. Rocky Dhir sits down with Shawn Tuma to discuss a range of recently enacted technology laws, helping attorneys understand their purpose, implications for legal practice, and considerations related to technology competence.  They explore key legislation including the Texas Responsible Artificial Intelligence Governance Act, Texas Cyber Command, and Cybersecurity Safe Harbor, offering insights into emerging best practices for technology in legal practice.  For a deeper dive, see Shawn Tuma's article co-authored with Christine Chase in the September 2025 issue of the Texas Bar Journal.  Shawn Tuma is a partner at Spencer Fane LLP in Cyber Risk Management, Cyber Incident Response, and Cyber Security, Hacking and Data Breach Litigation.

As artificial intelligence continues to evolve, new Texas laws are establishing a foundational framework for its governance, with a focus on the prevention of harm and ethical use. Rocky Dhir sits down with Shawn Tuma to discuss a range of recently enacted technology laws, helping attorneys understand their purpose, implications for legal practice, and considerations related to technology competence.  They explore key legislation including the Texas Responsible Artificial Intelligence Governance Act, Texas Cyber Command, and Cybersecurity Safe Harbor, offering insights into emerging best practices for technology in legal practice.  For a deeper dive, see Shawn Tuma's article co-authored with Christine Chase in the September 2025 issue of the Texas Bar Journal.  Shawn Tuma is a partner at Spencer Fane LLP in Cyber Risk Management, Cyber Incident Response, and Cyber Security, Hacking and Data Breach Litigation. Learn more about your ad choices. Visit megaphone.fm/adchoices

Don't let your small business fall victim to devastating cyber attacks! Expert     joins us t discuss AI Risks exposed. We explore how hackers use AI to target small businesses. From AI Social engineering to data theft, learn what you need to know to protect your business from cyber threats. Send us a textGrowth without Interruption. Get peace of mind. Stay Competitive-Get NetGain. Contact NetGain today at 844-777-6278 or reach out online at www.NETGAINIT.com Support the show

I reflect on changes in the indie hacking community, especially how Twitter's algorithm elevated a few “stars” and reduced sharing of useful lessons. I discuss how AI is transforming bootstrapping and SaaS, making coding accessible and raising anxiety about job security. I explore how software is becoming a commodity, what this means for developers and founders, and why owning distribution and marketing will matter most. I share thoughts on diversifying businesses beyond SaaS as AI rapidly evolves, and invite feedback from listeners about their own experiences with AI and entrepreneurship.Twitter: https://x.com/wbetiagoLinkedin: https://www.linkedin.com/in/tiago-ferreira-48562095/Timestamps by PodSqueezeIntroduction and Episode Overview (00:00:00)  Podcast Housekeeping and Call for Reviews (00:01:37)  Tiago's Indie Hacking Beginnings (00:03:06)  Golden Days of Indie Hacking Community (00:04:27)  Rise of Indie Hacking Stars and Algorithm Shift (00:05:45)  Vanity Metrics and Decline of Knowledge Sharing (00:07:17)  Personal Impact and Disconnection from Community (00:10:12)  Platform Comparison: Twitter vs. LinkedIn (00:12:47)  Transition to AI and Future of SaaS (00:14:13)  Personal Story: Co-founder's Journey with AI Coding Tools (00:14:13)  AI's Impact on Coding and Productivity (00:15:56)  AI in Daily Work and Expanding Use Cases (00:17:09)  Anxiety Over AI Replacing Computer-Based Jobs (00:20:08)  Threat of Big Tech and Commoditization of Software (00:21:31)  Changing Developer Job Market and Skills Gap (00:22:56)  Importance of Distribution and Marketing (00:25:56)  Existential Questions: AI Replacing Human Intelligence (00:27:16)  Human Value in a Post-AI World (00:31:48)  Diversification as a Survival Strategy (00:34:25)  Uncertain Future and Final Reflections (00:35:39)

A Quick Look at Sextortion at Scale Jan analyzed 1900 different sextortion messages using 205 different Bitcoin addresses to look at the success rate, lifetime, and other metrics defining these campaigns. https://isc.sans.edu/diary/A%20quick%20look%20at%20sextortion%20at%20scale%3A%201%2C900%20messages%20and%20205%20Bitcoin%20addresses%20spanning%20four%20years/32252 Azure AD Client Secret Leak Attackers are stealing Azure AD client secrets from websites that are leaving them exposed. https://www.resecurity.com/blog/article/azure-ad-client-secret-leak-the-keys-to-cloud Covert Channel via ICMP and DNS A new bot combines ICMP and DNS in new ways for covert communication. The DNS requests use domains with a fixed prefix followed by a base64 encoded command, and the ICMP echo request packets include commands as a payload. https://blog.xlab.qianxin.com/mystrodx_covert_dual-mode_backdoor_en/ Official Release of Critical FreePBX Patch Sangoma has announced that the experimental patch released for the exploited FreePBX vulnerability is now considered stable, and users should update to apply it. https://community.freepbx.org/t/security-advisory-please-lock-down-your-administrator-access/107203

Millions of people are living with unexplained symptoms like allergies, brain fog, anxiety, and chronic fatigue without realizing the hidden cause: mast cells gone rogue. In this episode of The Human Upgrade, Host Dave Asprey sits down with leading functional medicine physician Dr. Tania Dempsey to uncover how Mast Cell Activation Syndrome (MCAS) drives inflammation, disrupts mitochondria, and sabotages metabolism—and what you can do to switch it off. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Dempsey is internationally recognized for her work in functional medicine, biohacking, and chronic illness. She co-founded the AIM Center for Personalized Medicine, has published groundbreaking research on MCAS with Dr. Lawrence Afrin, and treats some of the most complex cases of immune dysregulation, autoimmune disease, and environmental illness. Her expertise helps you understand why mast cells are the missing link in allergies, long COVID, Lyme, mold toxicity, and even hormone disruption—and how to reclaim control of your biology. Dave and Dr. Dempsey break down how mast cells interact with mitochondria, hormones, and the nervous system, showing how chronic inflammation accelerates aging and blocks human performance. You'll discover why biohacking tools like fasting, ketosis, supplements, red light, cold therapy, sleep optimization, and smarter not harder lifestyle strategies all influence mast cell stability. They also explore why brain optimization, neuroplasticity, and nootropics are essential for calming inflammatory cascades, and how functional medicine provides practical solutions beyond conventional treatment. You'll Learn: • Why mast cells are the hidden switch behind allergies, chronic inflammation, and brain fog • How mitochondria and mast cells work together to drive human performance—or disease • The connection between toxic mold, Lyme, long COVID, hormone imbalance, and MCAS • How supplements, fasting, ketosis, and cold therapy stabilize mast cells and boost longevity • Why functional medicine and biohacking are essential for complex chronic illness • How mast cells impact metabolism, sleep optimization, and neuroplasticity • The surprising link between mast cells, anxiety, and mental health symptoms This episode is essential for anyone serious about hacking inflammation, protecting longevity, upgrading metabolism, and achieving high performance with resilience and clarity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: mast cell activation syndrome, MCAS, chronic inflammation, mitochondria dysfunction, histamine intolerance, functional medicine, biohacking, allergies, brain fog, long covid, mold toxicity, Bartonella, Lyme co-infections, oxalates, salicylates, mast cell stabilizers, immune dysregulation, neuroinflammation, chronic fatigue syndrome, autoimmune triggers, personalized medicine, longevity supplements Thank you to our sponsors!Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off.LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE.Resources: • Tania's Website: https://drtaniadempsey.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:10 — Introduction 03:27 — Why So Sick Today? 05:57 — MCAS Explained 08:33 — Mold & Environment 11:36 — Spotting MCAS 13:43 — Personal Stories 15:15 — Research & Biohacking 16:35 — Managing Triggers 20:15 — Gut & Stomach Acid 22:42 — Reaction Timing 25:30 — Hormones & MCAS 28:39 — Thyroid & Mitochondria 32:28 — Chronic Illness Navigation 40:06 — Insurance Battles 44:44 — Cholesterol & Ethics 49:11 — Personalized Care 53:24 — Circadian & Stress 58:24 — Testing Approaches 01:01:35 — Collagen & Joints 01:04:34 — MMPs & Aging 01:09:12 — Access & Experimentation 01:13:14 — MCAS & Mental Health 01:17:46 — Benzos & Stigma 01:20:23 — Vaccines & Spike Protein 01:25:18 — Research & Treatments 01:26:12 — Nicotine & Focus 01:29:24 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

pdf-parser: All Streams Didier released a new version of pdf-parser.py. This version fixes a problem with dumping all filtered streams. https://isc.sans.edu/diary/pdf-parser%3A%20All%20Streams/32248 Salesloft Drift Putting OAuth Tokens at Risk OAuth tokens used by Salesloft Drift users to provide access to integrations with Salesforce, Google Workspace, and others have been compromised and heavily abused for additional compromise and large-scale data exfiltration from exposed services. https://cloud.google.com/blog/topics/threat-intelligence/data-theft-salesforce-instances-via-salesloft-drift Velociraptor incident response tool abused for remote access Attackers are using the open source incident response tool Velociraptor to access remote systems in breached networks. Tools like Velocitraptor are ideal for attackers to perform lateral movement. https://news.sophos.com/en-us/2025/08/26/velociraptor-incident-response-tool-abused-for-remote-access/ Default Password in NeuVector (Rancher Desktop) SuSE fixed a default password vulnerability in NeuVector, a security tool included in Rancher Desktop. https://github.com/neuvector/neuvector/security/advisories/GHSA-8pxw-9c75-6w56

Want to work in cybersecurity but don't know where to begin? Or just curious what it takes to break into the field? This week, we're joined by the internet's very own Heath Adams, better known as The Cyber Mentor. He demystifies the application process and what it takes to build a career in cybersecurity – no matter your background.

Jon Sneider is the Founder, President, and Executive Producer of Wild Gravity, an award-winning creative production company. With more than 25 years of experience in marketing and advertising on the agency and client sides, he's held senior roles at L.L.Bean, Microsoft, and Redfin. Jon is also the author of Hacking Advertising, which talks about building effective advertising campaigns.  In this episode… Many businesses still rely on large agencies to produce their advertising, only to face bloated costs, long timelines, and diluted creative. The traditional agency model often creates inefficiencies, with multiple vendors and layers of approval that hinder the process. How can companies deliver world-class ads without sacrificing quality? Advertising veteran Jon Sneider has created an approach to challenge traditional advertising inefficiencies. He maintains that small, expert teams eliminate unnecessary hierarchies and deliver stronger results with less overhead. By focusing on breakthrough, brand and message recall, likability, and purchase intent, companies can create effective ads that scale industries. Additionally, combining AI with human expertise accelerates production while retaining high-performing creative.  In this week's episode of the Up Arrow Podcast, William Harris hosts Jon Sneider, Founder, President, and Executive Producer of Wild Gravity, to talk about reinventing advertising for efficiency and impact. Jon shares examples from high-performing insurance campaigns, his experience managing sales teams and advertising budgets at large corporations, and how growing up before the internet fueled his creativity.

LegalPwn technique hides LLMs prompts inside contract legalese Maryland Transit investigating cyberattack Hacker attempts to forge his way into Spanish university Huge thanks to our sponsor, ThreatLocker ThreatLocker® is a global leader in Zero Trust endpoint security, offering cybersecurity controls to protect businesses from zero-day attacks and ransomware. ThreatLocker operates with a default deny approach to reduce the attack surface and mitigate potential cyber vulnerabilities. To learn more and start your free trial, visit ThreatLocker.com/CISO. Find the stories behind the headlines at CISOseries.com.

Kurtis Minder, seasoned ransomware negotiator, shares insights into the complex world of cybercrime negotiations. He discusses the psychological aspects of negotiating with cybercriminals, the role of AI in both offense and defense, and the importance of understanding the motivations behind cybercrime. The conversation also touches on the evolving landscape of ransomware as a service and the implications for businesses and national security.Send us a textGrowth without Interruption. Get peace of mind. Stay Competitive-Get NetGain. Contact NetGain today at 844-777-6278 or reach out online at www.NETGAINIT.com Support the show

Most people track glucose or ketones, but almost no one is measuring the hidden signal that could be silently wrecking your metabolism, brain function, and longevity: uric acid. This episode reveals why this overlooked biomarker drives obesity, diabetes, cardiovascular disease, Alzheimer's, and even accelerated aging—and how you can hack it to unlock resilience, human performance, and smarter not harder health upgrades. Watch the podcast on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR We revisit host Dave Asprey sitting down with Dr. David Perlmutter, one of the world's leading functional medicine neurologists and the #1 New York Times bestselling author of Grain Brain and Drop Acid. Dr. Perlmutter has spent decades connecting gut health, brain optimization, and neuroplasticity with lifestyle interventions that truly change the trajectory of disease. In this conversation, he explains how uric acid acts as a metabolic switch that determines whether you burn fat or store it, whether your mitochondria power you up or slow you down, and whether your brain stays sharp or declines with age. They break down how fructose, purines, alcohol, and even dehydration spike uric acid, why Japan is decades ahead in using this as a health marker, and how supplements like quercetin and luteolin rival pharmaceuticals in keeping it under control. You'll also learn how ketosis, fasting, cold therapy, carnivore and plant-based approaches, and sleep optimization all interact with uric acid to shape your healthspan. This is biohacking at its most actionable—because once you measure this signal, you can control it, and once you control it, you radically upgrade your metabolism, your brain, and your longevity. This is essential listening for anyone serious about hacking their biology, building neuroplasticity, powering up mitochondria, exploring nootropics, and discovering smarter not harder ways to live longer and perform better. You'll Learn: • Why uric acid may be the most important overlooked biomarker for longevity • How it connects obesity, diabetes, cardiovascular disease, and Alzheimer's • The evolutionary reason your body uses uric acid as a survival signal • How fructose and hidden sugars sabotage metabolism and brain optimization • The role of quercetin, luteolin, and targeted supplements in lowering uric acid • Why measuring at home with a simple device can change your health trajectory • How functional medicine uses uric acid as a predictive tool for chronic disease Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: uric acid longevity, uric acid metabolism, fructose uric acid pathway, xanthine oxidase inhibition, quercetin uric acid, luteolin supplements, AMP kinase uric acid, AMP deaminase metabolism, uric acid and mitochondria, uric acid and neuroplasticity, uric acid Alzheimer's risk, uric acid dementia prevention, uric acid and nitric oxide, fructose metabolism hibernation biology, evolutionary mismatch uricase mutation, fructokinase inhibition, uric acid and insulin resistance, gout biohacking, uric acid and obesity, uric acid functional medicine Resources: • David's Website: https://drperlmutter.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 0:35 — Introduction 2:26 — Why Uric Acid Matters 5:55 — Measuring Uric Acid 8:17 — Disease Risk 9:38 — Metabolism Disruption 15:59 — What Raises Uric Acid 26:20 — Global Research 29:50 — Gut & Inflammation 32:55 — Seasonal Eating 47:36 — Brain Health 56:38 — Supplements & Testing 61:45 — The LUV Diet 71:41 — Closing Insights See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Increasing Searches for ZIP Files Attackers are scanning our honeypots more and more for .zip files. They are looking for backups of credential files and the like left behind by careless administrators and developers. https://isc.sans.edu/diary/Increasing%20Searches%20for%20ZIP%20Files/32242 FreePBX Vulnerability An upatched vulnerability in FreePBX is currently being exploited. FreePBX offers mitigation advice and has also just released a beta patch. https://community.freepbx.org/t/security-advisory-please-lock-down-your-administrator-access/107203 Passwordstate Vulnerability Clickstudios patched an authentication bypass vulnerability in its password manager, Passwordstate. The vulnerability can be used to access the emergency password page. https://www.clickstudios.com.au/passwordstate-changelog.aspx

Ido Ben-Natan, co-founder and CEO of Blockaid, joined me to discuss how Blockaid is helping to secure billions of dollars in crypto.Topics: - Blockaid's security services for exchanges, wallets and more - Blockaid secured $50 million in Series B funding - Common attacks, hacks, and scams in crypto - Will AI Agents be a threat to crypto? - Gemini and Hashgraph integration - The future of crypto security Show Sponsor -

Another one of those mindbending discussions between Jennifer, myself and folks offstage. In this podcast, we began talking about our previous week, which included Jennifer getting a flat tire at a wedding in Utah.   That led to a conversation about a dream I had the night before, where my old mentor Fred Roos (prolific producer, Oscar winner) showed up - and I asked Fred some questions about a documentary that he's appearing in - that hasn't been released yet, but premiered at the Venice film festival last night. When I refer to Mike, I'm referring to the director of that film, when I refer to Ellie, I'm referring to a film director and author who appears in the film (which Jennifer couldn't know) and the questions I ask her are based on my friendship with her since we met in the 1980's.  A generous and very profound person while on the planet. The reference to life being like an "electric toothbrush going off" when someone dies, came from her husband. And my questions about that quote were meant for those who would understand who that might be, and why I might ask it. Everyone who has been on the planet is available.  They may take time to get back to us, but we can ask them questions, ask them for help, ask them to participate in our journey.  Harry Dean Stanton is someone that Ellie knew well, and Fred knew well, and for those familiar with the podcast, we interviewed the great uber skeptic when he passed, and that conversation is in the film HACKING THE AFTERLIFE on Amazon Prime or Gaia. Harry tells us to tell people to "believe in the POSSIBILITY of an afterlife, so then they won't waste another minute of their lives arguing about it like I did." And he did. Anyone who knew him knows that to be the case. Podcast wraps up with an appearance by Prince (I asked Amelia Earhart who impressed her on the flipside) - and he does show up a lot when I ask that question. And Jennifer reminds me that I'm going to be on COAST TO COAST WITH GEORGE NOORY talking about the new book SHE WAS NEVER LOST; THE AMELIA EARHART SAGA - which isn't just talking to her via mediums (there is that) but also new information that shows many people saw her before she left the stage entirely - 7 years after her disappearance. Enjoy.

This week we broke a golden rule and crossed podcast streams with a pair of excellent guests, Richard Shotton and MichaelAaron Flicker, hosts of the Behavioural Science for Brands podcast and co-authors of the soon-to-be released (and definitely-to-be brilliant) Hacking The Human Mind. Richard is, of course, returning for a record third appearance on Call To Action® although we have respectfully honoured his request to not be left alone with Giles. Responsible for opening industry eyes to the potential of behavioural science, Richard is the author of two books that serious marketing types like you and I could not do without – The Choice Factory and The Illusion of Choice. Alongside him today, as is so often the case, is MichaelAaron Flicker, founder and president of (Zeeenno-Sigh) XenoPsi Ventures, a brand incubator firm that helps out all kinds of companies with financial, marketing and intellectual capital. As well as co-hosting their pod, and co-authoring their book, they've completed a hattrick of Co's by co-founding the Consumer Behaviour Lab, where they apply their considerable collective knowledge to help make marketing smarter, better and less stinky. In an episode where we open the sunroof on the human mind and reveal there's much more to it than day dreams, crippling doubt and song lyrics from 1996, we hear from two of the field's most compelling experts on what it really takes for a brand to be chosen. This episode is proudly dedicated to Rory Sutherland.    Follow Richard and MichaelAaron on LinkedIn.   ///// Timestamps 08:27 - Reflections on Career Path and Pivots 10:09 - Richard's Tribute to Ozzy Osbourne 12:39 - How Richard and Michael Met 14:22 - The Concept Behind Their New Book 16:01 - Writing Process and Collaboration Insights 20:21 - Discussion on Haagen-Dazs and Country of Origin Effect 25:04 - The Power of Naming: Patagonian Toothfish vs. Chilean Sea Bass 30:07 - Marketing Confusion Between Marketing and Sales Their Book Recommendations are: Alchemy by Rory Sutherland Tiny Habits by BJ Fogg /////

Your dopamine system is being hijacked every day, and the way to reclaim it might surprise you. This episode reveals how pain, pleasure, and addiction are wired in your brain, and how to use that knowledge for real brain optimization, resilience, and longevity. You'll discover why your dopamine levels control motivation, focus, mood, and even cravings—and the science-backed strategies that reset your neuroplasticity, metabolism, and reward system. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Anna Lembke, Stanford psychiatrist and bestselling author of Dopamine Nation. She is one of the world's leading experts on addiction, compulsive behavior, and the neuroscience of reward pathways. With decades of clinical work and groundbreaking research, she explains why dopamine has become the modern lens for understanding desire, distraction, and dysfunction—and how we can hack it to upgrade human performance. They break down how dopamine drives addiction, why pain can reset your reward system, and how simple practices like fasting, cold therapy, and supplements affect your brain chemistry. You'll learn how nicotine, GLP-1 drugs, and even nootropics alter dopamine sensitivity, and why overstimulation from social media, pornography, and ultra-processed food is creating an epidemic of anhedonia. The conversation also covers how functional medicine and biohacking can protect your mitochondria, restore your natural dopamine balance, and make your brain more resilient. You'll Learn: • Why dopamine itself is not addictive—and what really drives addiction • How pain, hormesis, and “dopamine fasting” can reset your reward system • Why social media and digital overstimulation create chronic dopamine deficit states • The role of GLP-1 drugs, nicotine, psychedelics, and other substances in rewiring dopamine • How functional medicine and supplements help restore dopamine balance • The connection between dopamine, mitochondria, fasting, cold therapy, and longevity • Why radical honesty and self-binding are powerful anti-addiction hacks This is essential listening for anyone serious about hacking dopamine for better focus, sleep optimization, metabolism, and long-term brain health. Whether you're curious about the link between dopamine and neuroplasticity, looking to upgrade human performance with smarter not harder tools, or just want to know how to stop dopamine hijacks from ruling your life, this episode gives you the science and strategies you need. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: dopamine fasting, pleasure-pain balance, dopamine deficit state, addiction neurobiology, anhedonia treatment, dopamine receptors, neuroadaptation gremlins, endogenous opioids, cold plunge dopamine, hormesis neuroscience, nucleus accumbens dopamine, L-Dopa addiction, GLP-1 and dopamine, social media addiction neuroscience, dopamine reward pathway, compulsive behavior psychiatry, dopamine and neuroplasticity, anhedonia supplements, functional medicine addiction, dopamine repair party Thank you to our sponsors! Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources: • Anna's Website: https://www.annalembke.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:10 — Introduction 5:47 — Pleasure–Pain Balance 6:45 — Homeostasis & Adaptation 8:22 — Addiction & Dopamine Deficit 10:14 — BICEP: Conscious Pain Exposure 14:26 — Adapting to Pleasure & Pain 20:20 — GLP-1s and Joy 21:39 — Modern Anhedonia 34:32 — Resilience in Young People 42:00 — Social Media & Mental Health 44:46 — Control & Addiction 55:14 — Dopamine Fasting 1:03:18 — Self-Binding Tools 1:07:56 — Psychedelics & Addiction 1:12:25 — Parenting in the Digital Age 1:14:39 — Progress & Outlook See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Interesting Technique to Launch a Shellcode Xavier came across malware that PowerShell and the CallWindowProcA() API to launch code. https://isc.sans.edu/diary/Interesting%20Technique%20to%20Launch%20a%20Shellcode/32238 NX Compromised to Steal Wallets and Credentials The popular open source NX build package was compromised. Code was added that uses the help of AI tools like Claude and Gemini to steal credentials from affected systems https://semgrep.dev/blog/2025/security-alert-nx-compromised-to-steal-wallets-and-credentials/ Countering Chinese State-Sponsored Actors Compromise of Networks Worldwide to Feed the Global Espionage System Several law enforcement and cybersecurity agencies worldwide collaborated to release a detailed report on the recent Volt Typhoon incident. https://www.cisa.gov/news-events/cybersecurity-advisories/aa25-239a

Michael Aaron Flicker, founder of XenoPsi Ventures and co-founder of the Consumer Behavior Lab with behavioral scientist Richard Shotton, joins John Jantsch to explore how psychology shapes the world's most successful brands. Drawing from their book Hacking the Human Mind, Michael shares insights into the hidden science behind consumer decisions and brand loyalty. Listeners will learn how to apply behavioral science to create more effective campaigns, craft memorable messages, and drive real business growth. Today we discussed: 00:00 Start 01:03 Meet Michael Aaron Flicker 01:46 Hacking the Human Mind 02:47 Do Brands Know Psychology? 04:05 Challenging Marketing Myths 05:57 Behavioral Science Lab Work 07:43 Apple's iPod Memory Trick 10:41 Why 17 is Magic 12:09 Surprising Brand Psychology 13:37 The Peak-End Rule 16:23 Ethics of Mind Hacking 18:19 Getting Started Guide Rate, Review, & Follow If you liked this episode, please rate and review the show. Let us know what you loved most about the episode. Struggling with strategy? Unlock your free AI-powered prompts now and start building a winning strategy today!

Can we build technology today to defend against the threats of tomorrow? This week, Technology Now concludes a double episode on post quantum cryptography and explores the subject of firmware, why it's imperative that it be protected against quantum attacks and why a simple update can't solve every problem. Nigel Edwards, Director of the Security Lab at HPE Labs, tells us more.This is Technology Now, a weekly show from Hewlett Packard Enterprise. Every week, hosts Michael Bird and Aubrey Lovell look at a story that's been making headlines, take a look at the technology behind it, and explain why it matters to organizations.About Nigel: https://www.linkedin.com/in/nigel-edwards-170591/?originalSubdomain=ukSources: https://www.theatlantic.com/technology/archive/2016/01/the-long-and-winding-history-of-encryption/423726/https://www.theqrl.org/blog/history-of-cryptography-behind-the-code-episode-1/https://www.theguardian.com/science/2025/may/07/todays-ai-can-crack-second-world-war-enigma-code-in-short-order-experts-say

FBI warns of expanded Chinese hacking campaign AI-powered ransomware is a thing now Anthropic warns about “vibe-hacking” Huge thanks to our sponsor, Prophet Security SOC analyst burnout is real - repetitive tasks, poor tooling, and constant alert noise are driving them out. Prophet Security fixes this. Their Agentic AI Analyst handles alert triage and investigation - work that 69% of cybersecurity leaders say is the best use for AI in the SOC. Say goodbye to burnout, and hello to efficiency. Check out prophetsecurity.ai.  

Getting a Better Handle on International Domain Names and Punycode International Domain names can be used for phishing and other attacks. One way to identify suspect names is to look for mixed script use. https://isc.sans.edu/diary/Getting%20a%20Better%20Handle%20on%20International%20Domain%20Names%20and%20Punycode/32234 Citrix Netscaler Vulnerabilities CVE-2025-7775, CVE-2025-7776 and CVE-2025-8424 Citrix patched three vulnerabilities in Netscaler. One is already being exploited https://support.citrix.com/support-home/kbsearch/article?articleNumber=CTX694938&articleTitle=NetScaler_ADC_and_NetScaler_Gateway_Security_Bulletin_for_CVE_2025_7775_CVE_2025_7776_and_CVE_2025_8424 git vulnerability exploited (CVE-2025-48384) A git vulnerability patched in early July is now being exploited https://github.com/git/git/security/advisories/GHSA-vwqx-4fm8-6qc9

(00:00-17:09) Trying not to let the Radio Wars affect The Spread Zone. Joe Lunardi has released bracketology in honor of the start of the college football season. What are the fats mad about? People are playing video poker in Wright City. Jackson speaks jive. Spillover in airplane seating. Putting naughty magazines on airplane seats to keep strangers from sitting next to you. When's the last time you bought a magazine? Dan Janson is on the phone wanting to know if Martin went to the golf thing with Chumley.(17:17-35:04) Very existential. Wilson Contreras get the six game suspension. Hacking is not coding. Jeremy is on the phone lines and he wants to lay hosanas at Doug's feet. How old is Jeremy? Just a summer fling. What's Jackson's age ceiling for a summer fling? How old is Charlize Theron? My head was in Vermont, but my feet were in Savanna.(35:14-48:51) Smack those chops, Doug. Reports are that Texas A&M may be one of Mizzou's yearly rival games in the SEC. Audio from the ‘Locked On Arkansas' podcast taking some shots at Mizzou for being the stinky kid in class. Are we gonna get a uniform announcement today? Don't forget about Felix Jones. Trouble just finds Doug. Reports of the Big 10 expanding to 20 teams by 2030 and Notre Dame will NOT be one of those teams.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Alzheimer's is not inevitable—and it may even be optional. In this groundbreaking episode, you'll learn how to prevent, slow, and in some cases reverse cognitive decline using strategies that also enhance brain optimization, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Dr. Dale Bredesen, a world-renowned neurologist and leading Alzheimer's researcher who has published over 240 peer-reviewed papers. Dr. Bredesen has spent decades proving that Alzheimer's is not a one-pathway disease but a network failure driven by inflammation, toxins, and mitochondrial dysfunction. His protocol has helped thousands of patients regain memory, extend healthspan, and reclaim brain performance. Together, they unpack how biohacking tools like fasting, ketosis, supplements, sleep optimization, cold therapy, and functional medicine can rewire neuroplasticity, protect mitochondria, and keep the brain in “connection mode” instead of decline. You'll hear why the pharmaceutical industry resists these solutions, how toxins like Paraquat and mold fuel cognitive decline, and what young people can do right now to bulletproof their brains for life. This episode is essential listening if you care about hacking human performance, upgrading metabolism, or extending longevity. You'll walk away with practical strategies you can use today—whether that means optimizing your mitochondria with nootropics, strengthening resilience with smarter not harder recovery, or fueling your brain with Danger Coffee. You'll Learn: • Why Alzheimer's can begin as early as your 20s and what biomarkers to track • The seven major drivers of Alzheimer's and how to reverse them with biohacking strategies • How APOE4 genetics, toxins, and inflammation accelerate brain aging—and what to do about it • The role of mitochondria, ketosis, and fasting in restoring brain optimization and neuroplasticity • Why prevention is exponentially easier than reversal and the top three actions you should start in your 20s • How to avoid “learned helplessness” in medicine and reclaim control over your brain span and longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Alzheimer's prevention biohacking, APOE4 genetics risk, mitochondrial dysfunction brain, network insufficiency model, cognitive decline reversal protocol, neuroplasticity longevity strategies, mild cognitive impairment treatment, subjective cognitive impairment biomarkers, ketoflex 12/3 diet, mycotoxins and Alzheimer's, Paraquat Parkinson's risk, mitochondrial transfusion therapy, fasting neuroprotection, ketosis brain optimization, natokinase soft plaque removal, sleep apnea cognitive decline, functional medicine Alzheimer's, hippocampal volume preservation, nootropics cognitive resilience, learned helplessness medicine Thank you to our sponsors! EMR-Tek | Go to https://www.emr-tek.com/DAVE and use code DAVE for 40% off.fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Resources: • Dale's Website: https://www.apollohealthco.com/dr-bredesen/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:10 — Introduction 2:43 — Personal Story 7:52 — APOE4, Genetics, and Drug Development 11:37 — Pharma, Media, and Pushback 17:13 — Prevention, Stages, and Biomarkers 23:34 — Causes and Mechanisms 30:24 — Parkinson's, Toxins, and Mitochondria 37:17 — Longevity, Biohacking, and Protocols 44:11 — AI, Data, and Future Treatments 54:11 — Case Studies and Success Stories 1:03:00 — Detox, Mold, and Environmental Triggers 1:12:00 — Neuroplasticity and Brain Regeneration 1:20:00 — Hormones, Supplements, and Personalized Hacks 1:29:00 — Cortisol, Addison's, and AI Protocols 1:38:00 — Large-Scale Trials and Global Impact 1:45:00 — Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Reading Location Position Value in Microsoft Word Documents Jessy investigated how Word documents store the last visited document location in the registry. https://isc.sans.edu/diary/Reading%20Location%20Position%20Value%20in%20Microsoft%20Word%20Documents/32224 Weaponizing image scaling against production AI systems AI systems often downscale images before processing them. An attacker can create a harmless looking image that would reveal text after downscaling leading to prompt injection https://blog.trailofbits.com/2025/08/21/weaponizing-image-scaling-against-production-ai-systems/ IBM Jazz Team Server Vulnerability CVE-2025-36157 IBM patched a critical vulnerability in its Jazz Team Server https://www.ibm.com/support/pages/node/7242925

Self-help is a popular genre of books, but not exactly a Christian idea. But here’s the trouble, in this age of distraction, we do need some help. Where do we find it?

The end of an era: Properly formatted IP addresses in all of our data. When initiall designing DShield, addresses were zero padded , an unfortunate choice. As of this week, datafeeds should no longer be zero padded . https://isc.sans.edu/diary/The%20end%20of%20an%20era%3A%20Properly%20formated%20IP%20addresses%20in%20all%20of%20our%20data./32228 .desktop files used in an attack against Linux Desktops Pakistani attackers are using .desktop files to target Indian Linux desktops. https://www.cyfirma.com/research/apt36-targets-indian-boss-linux-systems-with-weaponized-autostart-files/ Malicious Go Module Disguised as SSH Brute Forcer Exfiltrates Credentials via Telegram A go module advertising its ability to quickly brute force passwords against random IP addresses, has been used to exfiltrate credentials from the person running the module. https://socket.dev/blog/malicious-go-module-disguised-as-ssh-brute-forcer-exfiltrates-credentials Limiting Onmicrosoft Domain Usage for Sending Emails Microsoft is limiting how many emails can be sent by Microsoft 365 users using the onmicrosoft.com domain. https://techcommunity.microsoft.com/blog/exchange/limiting-onmicrosoft-domain-usage-for-sending-emails/4446167

Your hormones may be waging a hidden war that determines how long you live and how well you perform. This episode reveals how male and female biology diverge—and what those differences mean for your longevity, metabolism, and brain optimization. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Revisit this episode where Dave Asprey sits down with Teal Swan, a bestselling author and international speaker known for her work on human behavior, healing, and consciousness. Her insights bridge biology and psychology, uncovering how hormones, trauma, and environment shape both performance and resilience. Her ability to decode patterns of narcissism, victimhood, and trust through the lens of functional medicine and human performance makes her one of the most provocative voices in personal transformation. Together, they explore the science behind the hormonal divide between men and women—why birth control alters not just fertility but also male testosterone, why perception and neurodivergence impact neuroplasticity, and how early trauma imprints mitochondria and metabolism. You'll learn how fasting, ketosis, cold therapy, sleep optimization, and smarter not harder strategies can shift your biology toward higher resilience and greater longevity. They also break down the biohacking tools and supplements that can help balance hormones, upgrade mitochondria, and fuel nootropics-level brain performance. From the hidden biological costs of hormonal birth control to how carnivore and targeted nutrition affect both male and female healthspan, this episode gives you a framework for hacking your biology at the deepest level. This is essential listening for anyone serious about biohacking, hacking human performance, brain optimization, functional medicine, or understanding how masculine and feminine biology directly influence lifespan and resilience. You'll Learn: • How hormonal birth control impacts both women's fertility and men's testosterone • Why victim mentality rewires the brain and reduces neuroplasticity • How narcissism functions as a biological stress adaptation • The role of mitochondria, metabolism, and trauma in shaping healthspan • How fasting, ketosis, supplements, and cold therapy affect hormone balance • Why balancing male and female energetics may be a key to longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: hormone war, male vs female longevity, hormonal birth control effects, testosterone collapse, estrogen disruption, masculine vs feminine biology, victim mindset neuroscience, narcissism as adaptation, betrayal and biology, neuroplasticity and trauma, perception and neurodivergence, fractal vision, birth trauma programming, mitochondria and stress, species-level hormone imbalance, industrial hormone disruption, male fertility decline, female hormone resilience, functional medicine hormones Resources: • Teals Website: https://tealswan.com/ • Teal's YouTube: https://www.youtube.com/@TealSwanOfficial • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Cold Open 0:33 — Intro 2:49 — Defining Narcissism 5:48 — Gender Differences in Narcissism 7:47 — AI, Humanity, and the Future 10:25 — Extrasensory Perception & Childhood Experiences 14:04 — Birth Memories and Early Trauma 17:57 — Spiritual Abilities and Neurodivergence 22:48 — Functioning in the World with Unique Perceptions 23:45 — Trust, Support, and Creation 30:07 — Ego, Consciousness, and Spiritual Guides 33:46 — Dimensions and Multiverse Concepts 36:52 — Divine Masculine & Feminine 40:25 — Societal Imbalances and Gender Energies 46:20 — Hope for Humanity & Utopia 48:36 — Synchronization Workshops & Group Healing 51:30 — Science, Energy, and Invisible Communication 53:29 — Conclusion & Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Don't Forget The "-n" Command Line Switch Disabling reverse DNS lookups for IP addresses is important not just for performance, but also for opsec. Xavier is explaining some of the risks. https://isc.sans.edu/diary/Don%27t%20Forget%20The%20%22-n%22%20Command%20Line%20Switch/32220 watchTowr releases details about recent Commvault flaws Users of the Commvault enterprise backup solution must patch now after watchTowr released details about recent vulnerabilities https://labs.watchtowr.com/guess-who-would-be-stupid-enough-to-rob-the-same-vault-twice-pre-auth-rce-chains-in-commvault/?123 Docker Desktop Vulnerability CVE-2025-9074 A vulnerability in Docker Desktop allows attackers to escape from containers to attack the host. https://docs.docker.com/desktop/release-notes/#4443

Walking speed predicts your risk of death better than cholesterol—and this episode reveals why. You'll learn how to test your biological age at home in just 10 seconds, and how to use that information to upgrade your human performance, extend your longevity, and tailor your biohacking strategy for maximum results. Discover the overlooked role of pelvic floor strength, glute activation, and neuromuscular training in brain optimization, metabolism, and injury prevention. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey speaks with Dr. Vonda Wright, a double board-certified orthopedic surgeon, hormone optimization expert, and elite sports medicine pioneer who's worked with Olympic athletes, military special forces, and high-performing women through every phase of life. With decades of experience in functional medicine, movement science, and hormone therapy, Dr. Wright shares the essential strategies to prevent frailty, rebuild strength, and thrive through perimenopause and beyond. You'll learn: • How walking speed reveals aging and longevity better than traditional blood tests • The biomechanics behind muscle “shutdown” and how to turn muscles back on • The truth about C-sections, pelvic floor rehab, and functional motion assessments • Which supplements, nootropics, and hormone therapies restore metabolism and vitality • Why perimenopause is a turning point for brain, bone, and cardiovascular health • Testing tools and training methods to upgrade strength, prevent falls, and age powerfully Whether you want to feel stronger, think sharper, or stay youthful into your 90s, this is your roadmap for smarter not harder biohacking with real-world impact. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: 10-second walk test longevity, pelvic floor dysfunction and aging, glute activation for brain health, perimenopause hormone replacement therapy, VO2 max biohacking, estrogen for bone density, neuromuscular reactivation exercises, functional movement assessment AI, post-C-section core recovery, velocity training for longevity, strength vs muscle mass aging, menopause testosterone therapy, mitochondrial health for women, sleep optimization progesterone, cold therapy for muscle recovery, fascia training for anti-aging, diastasis recti long-term effects, smart exercise hacks for aging, hormone optimization for libido and brain, smarter not harder fitness protocols Thank you to our sponsors! Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. Resources: • Vonda's Website: https://www.drvondawright.com/ • Vonda's Instagram: https://www.instagram.com/drvondawright/?hl=en • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer1:23 — Intro2:55 — Muscle Atrophy and Reactivation6:10 — Pelvic Floor Health and Rehab8:47 — Joint Mobility and Movement10:02 — Science of Muscle Function18:23 — Perimenopause and Menolescence27:58 — Four Essential Female Hormones42:50 — VO2 Max and Longevity49:24 — Velocity Training and Bone Health62:30 — Turning Menopause into Power65:58 — Closing Thoughts and Book Rec See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade your mitochondria, and extend your healthspan. This episode gives you the real science, proven by over 250 studies, behind supplements, nutrition, and biohacking tools that actually work for brain optimization, metabolism, and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You'll learn why NAD+ is a master regulator of mitochondrial health, how DNA methylation clocks accurately measure biological age, and why boosting sirtuin activity improves resilience, neuroplasticity, and recovery. Dr. Guarente shares insider strategies from decades of functional medicine research, including nootropics, targeted supplements, fasting protocols, and diet adjustments from carnivore to Mediterranean that can shift your metabolism toward longevity. Dave and Dr. Guarente explore advanced biohacks like cold therapy, sleep optimization, and ketosis, plus how to balance these interventions with your genetics, lifestyle, and health goals. You'll also hear about the surprising role of homocysteine in brain aging, how to use lab testing to guide your longevity plan, and why resilience is the ultimate measure of health. You'll learn: • How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk Whether you want to sharpen your brain, protect your heart, or upgrade your energy systems, this is a masterclass in smarter not harder biohacking for a longer, higher-performing life.Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: NAD+ supplementation, Sirtuin activation, DNA methylation clocks, Biological age testing, Mitochondrial biogenesis, Epigenetic reprogramming, Pterostilbene benefits, Nicotinamide riboside (NR), Nicotinamide mononucleotide (NMN), Homocysteine reduction, Oxidative stress repair, Superoxide dismutase (SOD) activation, Functional medicine longevity, Healthspan optimization, Resveratrol bioavailability, Menopause mitochondrial support, Phenylbutyrate and protein folding, High-fat diet longevity studies, Neurodegenerative disease biohacking, INCHIANTI aging study Thank you to our sponsors! Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Elysium Website. Use code ‘UPGRADE25' for 25% off the first month of a monthly subscription to any Elysium supplement: https://www.elysiumhealth.com/ • Dave Asprey's Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction to NAD & Sirtuins 0:59 — Intro 7:04 — Animal vs Human Aging Studies 10:07 — Discovery of Sirtuins 14:43 — NAD's Role in Aging 15:34 — Resveratrol vs Pterostilbene 23:13 — Timing NAD Supplementation 36:34 — Diet & Lifestyle Factors 50:05 — Elysium's Basis & Signal 1:00:03 — Future Clinical Trials 1:05:14 — Psychology of Aging & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We track our steps and our sleep, guzzle supplements and protein shakes, and even inject hormones – all in the name of wellness. This episode was produced by Hady Mawajdeh, edited by Naureen Khan and Miranda Kennedy, fact-checked by Melissa Hirsch, engineered by Andrea Kristinsdottir, and hosted by Jonquilyn Hill. Photo by Jeffrey Greenberg/Universal Images Group via Getty Images. If you have a question, give us a call on 1-800-618-8545 or send us a note here. Listen to Explain It to Me ad-free by becoming a Vox Member: vox.com/members.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

We track our steps and our sleep, guzzle supplements and protein shakes, and even inject hormones – all in the name of wellness. This episode was produced by Hady Mawajdeh, edited by Naureen Khan and Miranda Kennedy, fact-checked by Melissa Hirsch, engineered by Andrea Kristinsdottir, and hosted by Jonquilyn Hill. Photo by Jeffrey Greenberg/Universal Images Group via Getty Images. If you have a question, give us a call on 1-800-618-8545 or send us a note here. Listen to Explain It to Me ad-free by becoming a Vox Member: vox.com/members.  Learn more about your ad choices. Visit podcastchoices.com/adchoices