Podcasts about brian kobilka

Nobel prize laureates are pushing back against President-elect Donald Trump's choice to lead the Department of Health and Human Services. In a letter from earlier this week, the group asked Senators to oppose Robert F. Kennedy Jr.'s confirmation to the job. They say he would “put the public's health in jeopardy and undermine America's global leadership in the health sciences.”Kennedy has promoted conspiracy theories including one that pushes that COVID-19 was created to target certain racial groups and give other groups immunity. He has also denied the link between HIV and AIDS, a scientific discovery that has helped to treat and prevent AIDS around the world. Kennedy has also embraced the debunked theory that childhood vaccines cause autism. Dr. Brian Kobilka, a 2012 Nobel Laureate in chemistry is one of the scientists trying to prevent Kennedy from being confirmed as leader of the Department of Health and Human Services. Kobilka is originally from Little Falls and attended the University of Minnesota Duluth. He's now a professor at Stanford University and joined Minnesota Now to talk about his concerns.

In this episode of The Brainy Business podcast, host Melina Palmer welcomes Nobel Prize winner Dr. Bob Lefkowitz for an insightful discussion on mentorship, focus, and the power of saying no. Dr. Lefkowitz, a distinguished professor at Duke University Medical Center, shares his journey from a passionate physician to a Nobel laureate in Chemistry, highlighting the impact of his research. Dr. Lefkowitz delves into the importance of mentorship, recounting his own experiences and the significance of his mentee, Brian Kobilka, with whom he shared the Nobel Prize. He emphasizes the value of asking good questions, being thoughtful, and the crucial skill of focusing like a laser on what truly matters. This episode is packed with wisdom on how to balance stubborn pursuit with strategic decision-making in both scientific research and business. In this episode: Understand the significance of mentorship and how it shapes successful careers. Discover the importance of focus and saying no to distractions. Gain insights into the power of storytelling and synthesizing data. Explore practical advice for fostering creativity and seeing things from different perspectives. Show Notes: 00:00:00 - Introduction Melina introduces Nobel Prize winner Dr. Bob Lefkowitz, highlighting his distinguished career and contributions to science and medicine. 00:04:30 - Dr. Lefkowitz's Background Dr. Lefkowitz shares his journey from aspiring physician to Nobel laureate, detailing his research on G protein-coupled receptors. 00:10:15 - The Importance of Focus Dr. Lefkowitz discusses the critical role of focus in achieving success and how he developed this skill over his career. 00:15:45 - Mentorship and Its Impact The conversation shifts to mentorship, with Dr. Lefkowitz sharing his thoughts on what makes a great mentor and the legacy of training successful scientists. 00:25:00 - Storytelling in Science Dr. Lefkowitz emphasizes the power of storytelling in presenting scientific data and making impactful discoveries. 00:30:20 - The Power of Saying No Dr. Lefkowitz provides practical advice on how to say no to distractions and focus on what truly matters. 00:35:50 - Creativity and Humor The discussion highlights the role of creativity and humor in scientific discovery and problem-solving. 00:45:00 - Closing Thoughts Melina and Dr. Lefkowitz wrap up the conversation, reflecting on the key takeaways and the importance of thoughtful mentorship. 00:50:30 - Conclusion What stuck with you while listening to the episode? What are you going to try? Come share it with Melina on social media -- you'll find her as @thebrainybiz everywhere and as Melina Palmer on LinkedIn. Thanks for listening. Don't forget to subscribe on Apple Podcasts or Android. If you like what you heard, please leave a review on iTunes and share what you liked about the show.  I hope you love everything recommended via The Brainy Business! Everything was independently reviewed and selected by me, Melina Palmer. So you know, as an Amazon Associate I earn from qualifying purchases. That means if you decide to shop from the links on this page (via Amazon or others), The Brainy Business may collect a share of sales or other compensation. Let's connect: Melina@TheBrainyBusiness.com The Brainy Business® on Facebook The Brainy Business on Twitter The Brainy Business on Instagram The Brainy Business on LinkedIn Melina on LinkedIn The Brainy Business on Youtube Connect with Dr. Lefkowitz:  LinkedIn Learn and Support The Brainy Business: Check out and get your copies of Melina's Books.  Get the Books Mentioned on (or related to) this Episode: What Your Employees Need and Can't Tell You, by Melina Palmer The Ultimate Guide to Great Mentorship, by Scott Miller Mentoring, by Dr. Ruth Gotian and Andy Lopata A Funny Thing Happened on the Way to Stockholm, by Robert J. Lefkowitz M.D. The Speed of Trust, by Stephen M.R. Covey Top Recommended Next Episode: Ruth Gotian Interview (ep 419) Already Heard That One? Try These:  Vulnerability Loops (ep 229) Unity (ep 216) Scott Miller Interview (ep 69) Confirmation Bias (ep 260) Focusing Illusion (ep 330) Other Important Links:  Brainy Bites - Melina's LinkedIn Newsletter

Today, I sat down with Dr. Brian Kobilka, Professor in the Department of Molecular and Cellular Physiology at Stanford University School of Medicine. Dr. Kobilka is an expert on a class of receptors called G protein-coupled receports, or GPCRs, that are essential in a majority of biological processes including light, flavor, and odor perception and in the activity of adrenalin, dopamine, and serotonin. In fact, currently approximately half of all pharmaceuticals on the market target GPCRs. In the mid 1980s Dr. Kobilka and his colleagues from the Robert Lefkowitz lab were the first to clone the gene for an important GPCR called the beta2-adrenergic receptor, and later he and his collaborators were the first to determine its molecular structure, which served as the basis for understanding all subsequent GPCRs and creating drugs to target them. This work proved to be revolutionary in many areas of science and medicine, such that in 2012, Kobilka was awarded the Nobel Prize in Chemistry for his contributions to understanding GPCRs. In this interview, we talk about these amazing findings and the recent advances in understanding this important class of receptors. Title music: World Is Holding Hands by WinnieTheMoog https://creativecommons.org/licenses/by/4.0/legalcode

Dr Robert Joseph Lefkowitz is an American physician, biochemist and Nobel Prize winner. He is best known for his groundbreaking discoveries that reveal the inner workings of an important family G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka. He is currently an Investigator with the Howard Hughes Medical Institute as well as a James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University. Connect with us: https://freedompact.co.uk/newsletter​ (Healthy, Wealthy & Wise Newsletter) https://instagram.com/freedompact​ https://tiktok.com/personaldevelopment https://twitter.com/freedompactpod freedompact@gmail.com Connect with Dr Lefkowitz: https://medicine.duke.edu/profile/robert-j-lefkowitz http://pegasusbooks.com/books/a-funny-thing-happened-on-the-way-to-stockholm-9781643136387-hardcover

1:13  Labiotech news3:09  Lund Spring Symposium27:36 SapientSapientSapient is an end-to-end biomarker discovery organization dedicated to accelerating the mapping of circulating chemistries in humans through rapid, large-scale small molecule biomarker profiling. Its platform combines next-generation mass spectrometry technologies capable of assaying tens of thousands of small molecule biomarkers in human biosamples, advanced biocomputational learning, and a proprietary Human Biology Database with extensive data from several hundred thousand biosamples. Together these approaches enable rapid discovery and validation of circulating biomarkers of health, disease, and drug responsiveness at unprecedented speed and scale.We spoke with founder and CEO of Sapient, Mo Jain. Lund Spring SymposiumThe inaugural Lund Spring Symposium held in Lund, Sweden from May 24 to 26. It was an impressive forum where an exceptional set of international and national top researchers, entrepreneurs, and business leaders gathered around the subject of ‘Enabling Novel Therapeutic Principles,' with examples of actual treatment breakthroughs, as well as novel modalities across therapeutic areas ranging from cancer, COVID-19 to neuroscience.Six researchers were awarded for their groundbreaking discoveries and outstanding achievements: Craig Crews Yale University; Brian Kobilka, Stanford University; Robert Langer, MIT; Jude Samulski, University of North Carolina; Sarah Tabrizi, University College London; and Drew Weissman, University of Pennsylvania.The symposium also featured two other Nobel Prize laureates, David Julius, from the University of California San Francisco, who gave a presentation, and Bengt Samuelsson, after whom one of the awards was named.The organizer, Lars Grundemar, Lund University and AGB Pharma, decided together with Mikael Dolsten, Lund University, and chief scientific officer, president R&D, Pfizer, and Claes Wahlestedt, Lund University and University of Miami Miller School of Medicine, to create the event featuring high-profile international and local researchers at a symposium in Lund to raise the profile of pharmacology as a cross-functional discipline in the 21st century, and to provide a forum to facilitate collaborations across academia and industry.“This event was designed to reflect the importance of combining basic research with clinical applications and entrepreneurship in successful development of novel therapeutic principles,” Grundemar said. The symposium was intended for scientists and entrepreneurs to be an engaging and interactive forum to broaden the participants' horizons of cutting-edge science.The Lund Spring Symposium will be held biannually, with the next event taking place in 2025.

If you've ever experienced the so-called fight or flight response, you'll know about the rush of adrenaline you get when something triggers your sense of fear. Your heart beats faster. Your blood pressure goes up. Your breathing gets more rapid. Why? Because the adrenalin that your body produces interacts with receptors on cells around the body. Like a key in a lock, the adrenalin binds and triggers a response in those cells which leads to all those fight or flight symptoms you experience.And equally you can block those receptors. Ever heard of beta blockers or anti-histamines? Well they're blocking those same receptors to dampen down the body's natural response.The thing is, we didn't always know how it was that cells knew about the world around them. It was Dr Robert Lefkowitz and his team that first isolated and studied cell receptors, and later discovered their protein structure. Today between 30 and 50% of all the prescription drugs in the world act by activating or inhibiting the receptors of the type that Dr Lefkowitz and his team isolated and characterised.For this discovery, he has received more than 70 awards and in 2012 he and his former trainee Dr Brian Kobilka were together awarded the Nobel Prize in Chemistry.Dr Robert is the Chancellor's Distinguished Professor of Medicine and Professor of Biochemistry at Duke University in North Carolina, where he's been an investigator since the mid-1970s.He's led an extraordinary life and I know he's a master storyteller. I can't wait to hear more about his journey in medicine, science and life, and to hear his reflections on the Unlock Moments of remarkable clarity he's experienced along the way.--Dr Robert Lefkowitz - https://medicine.duke.edu/profile/robert-j-lefkowitzA Funny Thing Happened on the Way to Stockholm: The Adrenaline-Fueled Adventures of an Accidental Scientist - https://www.amazon.co.uk/Funny-Thing-Happened-Stockholm-Adrenaline-Fueled/dp/1643136380

For more details, visit #DrGPCRPodcast Episode #58 page https://www.drgpcr.com/episode-58-with-juan-jose-fung/ ------------------------------------------- About Dr. Juan José Fung Dr. Juan José Fung is a Principal Scientist at GPCR Therapeutics, Inc, a drug discovery company focused on targeting GPCR heteromers in cancer, headquartered in Seoul, Korea, with an R&D facility in the SF Bay Area. Dr. Fung received his Ph.D. from the Stanford University School of Medicine under the mentorship of Dr. Brian Kobilka, studying the dimerization of GPCRs. Dr. Fung continued his Postdoctoral training in Dr. Kobilka's lab contributing to the elucidation of high-resolution structures of various GPCRs. Dr. Fung has spent significant time in the industry studying membrane proteins, antibodies, and HTS methods for drug discovery. His current work is mainly focused on screening and assay development to bridge the gap between in vitro and in vivo GPCR pharmacology. Dr. Juan José Fung on the web LinkedIn Website ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us who are working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. To build our #GPCR Ecosystem, we created various enabling outlets. For more details, visit our website http://www.DrGPCR.com/Ecosystem/. ------------------------------------------- Are you a #GPCR professional? - Register to become a Virtual Cafe speaker http://www.drgpcr.com/virtual-cafe/ - Subscribe to our Monthly Newsletter http://www.drgpcr.com/newsletter/ - Listen and subscribe to #DrGPCR Podcasts http://www.drgpcr.com/podcast/ - Support #DrGPCR Ecosystem with your Donation. http://www.drgpcr.com/sponsors/ - Reserve your spots for the next #DrGPCR Virtual Cafe http://www.drgpcr.com/virtual-cafe/ - Watch recorded #DRGPCR Virtual Cafe presentations: https://www.youtube.com/channel/UCJvKL3smMEEXBulKdgT_yCw - Bring in a #GPCR Consultant http://www.drgpcr.com/consulting/

The press called him the happiest laureate, which he was. In 2012, Robert Lefkowitz was awarded the Nobel Prize in Chemistry together with his colleague and former fellow Brian Kobilka. Listen to his experience of the Nobel Week and how he ended up being a question on Jeopardy. Robert Lefkowitz, Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University and Investigator at the Howard Hughes Medical Institute, is known for his stories. In this podcast episode he tells a few of them - what made the Nobel Week so special, how his banquet speech ended up being a comment on the politicalization of science in the US and how his uncle Henry got all excited when Lefkowitz was featured on Jeopardy.

Our conversation with Dr. Brian Kobilka, recipient of the 2012 Nobel Prize in Chemistry for studies of G-protein-coupled receptors and Professor of Molecular and Cellular Physiology at Stanford University. Dr. Kobilka is a humble, passionate scientist who strongly believes in the importance of collaboration in science. Tune in to hear about his incredible story. See more about him and his work at https://med.stanford.edu/kobilkalab.html.

This episode almost became a 3 hour long one - Robert "Bob" Lefkowitz, PhD., is a phenomenal, infinite source of knowledge. Dodi and Conor are still an awe and deep appreciation for the time spent with the 2012 Nobel Prize laureate for Chemistry (shared with Brian Kobilka). Dive in and listen to the #discoverymakers story of Bob Lefkowitz talking about humor, creativity and resilience in science discoveries.

It was December 14th, 2020, 1:50 pm, when I turned on my laptop and signed into Zoom for my chat with Bob. Bob, who, you might ask? Well, it's the one and only Robert J. Lefkowitz, M.D., 2012 Nobel Prize in Chemistry, which he shared with Dr. Brian Kobilka. Bob doesn't really need an introduction since his reputation precedes him. Before we pressed record, I asked if I could call him Bob, and he answered that only his mom used to call him Robert, especially when she was upset with him. I then pressed record, and we chatted for almost 2h about Bob's career, discoveries, difficulties (yes, he's had some too), Nobel week, and his memoir that he just published in collaboration with Dr. Randy Hall. Bob is James B. Duke Professor of Medicine and Professor of Biochemistry, Chemistry, and Pathology at the Duke University Medical Center. He began his career in the late 1960s and has been an Investigator of the Howard Hughes Medical Institute since 1976. His legacy lies in the numerous discoveries he and his team made in the GPCR field and in all those who trained in his laboratory and went on to pursue stellar scientific careers. I very much enjoyed chatting with Bob, and I hope you'll enjoy learning more about him as well. http://www.drgpcr.com/episode-27-dr.-robert-j-lefkowitz/

New drugs for old bugs: We should all be worried by the growing number of antibiotic-resistant bacteria and we urgently need to develop new drugs, says Ada Yonath. She and Brian Kobilka won Nobel Prizes for using x-ray crystallography to understand cell structures that are vital targets for drug development. In this film, three researchers challenge the structural approach and propose alternative ways to find drugs; some cutting edge, such as computation, and some ancient, such as searching for chemicals deep in the rain forest. What is the best way forward? Or is a combination of techniques the most promising approach?

In this month's Cell Podcast, we learn how llamas have helped the study of G protein-coupled receptors, with Brian Kobilka (0:00) (Trends in Pharmacological Sciences), how to teach an old genetic analysis test a cool new trick, with Trey Ideker (10:50) (Cell Reports). Plus, sample a selection of the hottest new papers from Cell Press (17:00).

Brian Kobilka, MD, professor and chair of molecular and cellular physiology, discusses winning this year's Nobel Prize in Chemistry. (October 26, 2012)

Brian Kobilka y Robert Lefkowitz han ganado el premio Nobel de Qu

Nobelprisen i kjemi: Robert Lefkowitz og Brian Kobilka har fått prisen for at de har kartlagt hvordan en stor og viktig familie av reseptorer, kalt G-protein-koblede reseptorer, fungerer. Hvor lenge kan vi overleve på røtter og bær, og hva slags røtter kan vi spise?

The 2012 Nobel Prize in Chemistry was awarded jointly to Robert J. Lefkowitz and Brian Kobilka for studies of G-protein-coupled receptors, which are the portals by which information about the environment reaches the interior of cells and leads to their responses. About half of all drugs work by interacting with G-protein-coupled receptors