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In this episode of the Dr. GPCR Podcast, we step outside the lab to talk about what keeps research-driven organizations running behind the scenes: finance and operations. Yamina Berchiche is joined by Joe St. Germain and Chuck DeWeese from Company Launch Partners to discuss the real-world challenges of building startups and nonprofits—including Dr. GPCR itself. Joe shares his leap from corporate finance to launching a firm that supports early-stage ventures, while Chuck explains his journey from sales to becoming the behind-the-scenes problem-solver for mission-driven organizations.What emerges is a compelling conversation about how science and finance are more similar than we think. Chuck and Joe explain how reconciling financial data mirrors the satisfaction of solving scientific puzzles. They also dive into the unique hurdles of accounting for grants, setting up sustainable financial systems, and choosing clients whose values align with their own. The episode bridges two traditionally separate worlds—science and business—by highlighting their shared reliance on structure, integrity, and impact.At its core, the episode is about building things that last—with the right people. From hiring based on character and teachability to growing teams organically through trust and mentorship, Joe and Chuck share lessons that resonate far beyond finance. Whether you're a GPCR scientist applying for a grant or a founder navigating early growth, this conversation is a powerful reminder that success is never solo—it's built on relationships, purpose, and a clear sense of mission.Watch the complete episode at: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-165-with-chuckdeweese-joestgermain
In this science-focused episode of the Dr. GPCR podcast, we meet Dr. Ian Chronis, a freshly minted PhD from the University of Michigan. While his academic roots started in classical history and ancient Greek, Ian's curiosity pulled him toward chemistry, then pharmacology, and eventually into the complex world of GPCR signaling. His story is a testament to the power of staying open to change and following emerging scientific questions wherever they lead.Ian's doctoral work focused on two key GPCR systems: the well-characterized β2-adrenergic receptor and the lesser-known proton-sensing receptor GPR65. In the former, he explored how PKA phosphorylation modulates receptor interactions and discovered a regulatory role for 14-3-3 proteins. But it's GPR65 — a receptor that constitutively internalizes and signals from acidic endosomes — that has captured Ian's attention and become the centerpiece of his current research. Unlike classical GPCRs, GPR65 uses non-canonical internalization mechanisms, presenting new opportunities to uncover novel biology.The receptor's ability to signal within the tumor microenvironment and immune cells makes it an emerging drug target, especially in cancer immunotherapy. However, there are still major gaps: no selective ligands, little clarity on its internalization machinery, and limited tools to modulate its function. Ian's wish list? A high-affinity agonist and antagonist to begin untangling these questions. Until then, he's carefully optimizing pH-based assays and preparing for next steps in a postdoctoral lab focused on more physiological and therapeutic systems.Whether he's decoding novel trafficking pathways or reflecting on career strategy, Ian brings a balanced perspective that's both ambitious and grounded. His advice to peers? Attend talks outside your field, learn constantly, and surround yourself with people who make science sustainable. This episode is a must-listen for those navigating the intersection of curiosity, technical rigor, and translational potential in the GPCR research community.Watch the video version of this podcast episode:https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-164-with-dr.-ian-chronis---------------------------------Become a #DrGPCR Ecosystem Member---------------------------------Imagine a world in which the vast majority of us are healthy.The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of #GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.---------------------------------To build our #GPCR Ecosystem, we created various enabling outlets.Premium YearlyPremium Yearly for TeamsDeveloping CountriesAre you a #GPCR professional?Subscribe to the Classified GPCR Weekly NewsListen and subscribe to #DrGPCRPodcast
Ask the Right GPCR Question: A Conversation with Prof. Dmitry VeprintsevIn this episode, Yamina sits down with Prof. Dmitry Veprintsev, a molecular pharmacologist at the University of Nottingham, to discuss his scientific journey, GPCR research, and the intersection of academia and entrepreneurship.Watch the video version of this podcast episode:https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.-dmitry----------------------------------Become a #DrGPCR Ecosystem Member---------------------------------Imagine a world in which the vast majority of us are healthy.Dr. GPCR is dedicated to fostering a collaborative ecosystem focused on GPCRs. By connecting researchers, sharing knowledge, and facilitating partnerships, the #DrGPCR Ecosystem provides resources to support advancements in GPCR drug discovery.The ecosystem includes a variety of initiatives designed to inform and engage the scientific community, from courses and news updates to networking opportunities.---------------------------------Learn more about Dr. GPCR: https://www.ecosystem.drgpcr.com/ Membership & Pricing: https://www.ecosystem.drgpcr.com/university-pricing Dr. GPCR Courses: https://www.ecosystem.drgpcr.com/gpcr-courses GPCR Weekly News: https://www.ecosystem.drgpcr.com/gpcr-news/categories/gpcr-weekly-news
Watch the video version of this podcast episode: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-162-with-dr-gabriele-kockelkoren---------------------------------Become a #DrGPCR Ecosystem Member---------------------------------Imagine a world in which the vast majority of us are healthy.Dr. GPCR is dedicated to fostering a collaborative ecosystem focused on GPCRs. By connecting researchers, sharing knowledge, and facilitating partnerships, the #DrGPCR Ecosystem provides resources to support advancements in GPCR drug discovery.The ecosystem includes a variety of initiatives designed to inform and engage the scientific community, from courses and news updates to networking opportunities.---------------------------------Learn more about Dr. GPCR: https://www.ecosystem.drgpcr.com/ Membership & Pricing: https://www.ecosystem.drgpcr.com/university-pricing Dr. GPCR Courses: https://www.ecosystem.drgpcr.com/gpcr-courses GPCR Weekly News: https://www.ecosystem.drgpcr.com/gpcr-news/categories/gpcr-weekly-news
Watch the video version of this podcast episode.https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-161-with-dr.-brian-hudson---------------------------------Become a #DrGPCR Ecosystem Member---------------------------------Imagine a world in which the vast majority of us are healthy.The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.---------------------------------To build our #GPCR Ecosystem, we created various enabling outlets. Individuals OrganizationsAre you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
$150 billion. That's how much some experts estimate weight-loss drugs could bring in in sales within the next five years. Motley Fool analyst Karl Thiel joins Ricky Mulvey to check in on the GLP-1 landscape. They also discuss: - How weight-loss drugs actually work, and how big-name prescriptions differ from each other. - What investors need to know about Ozempic and Mounjarno's patent cliffs. - The scenarios in which Novo Nordisk and Eli Lilly are actually undervalued. Companies discussed: LLY, NOVO, HIMS, PFE, RHHBY, VKTX, GPCR, ISRG Host: Ricky Mulvey Guest: Karl Thiel Producer: Mary Long Engineer: Rick Engdahl Learn more about your ad choices. Visit megaphone.fm/adchoices
Watch the video version of this podcast episode.https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-160-with-dr.-remi-janicot---------------------------------Become a #DrGPCR Ecosystem Member---------------------------------Imagine a world in which the vast majority of us are healthy.The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.---------------------------------To build our #GPCR Ecosystem, we created various enabling outlets. Individuals OrganizationsAre you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Register for the next Dr. GPCR University course before February 14th https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias Spots are limited! _________ Watch the video version of this podcast episode. https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-159-with-dr.-riccardo-capelli --------------------------------- Become a #DrGPCR Ecosystem Member --------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. --------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. --------------------------------- Become a #DrGPCR Ecosystem Member --------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. --------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts • • Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Obesity is one of the most pressing health challenges of our time, with genetic and molecular factors playing a crucial role in how our bodies regulate weight. In this season opener, we explore the science behind obesity, focusing on how hormones, genetics, and brain circuits influence feeding behavior and body weight. Join us for a fascinating discussion about the interplay between molecular biology and real-world health outcomes.Our guest, Dr. Giles Yeo, is a professor of molecular neuroendocrinology at the University of Cambridge and an expert in the genetics of obesity. With decades of research experience, Dr. Yeo dives into how hormones like GLP-1 interact with the brain and how genetic mutations can affect eating behaviors. He also explains the innovative molecular biology techniques his lab uses to map brain circuits and decode the genetic influences on body weight.But this episode isn't all about the lab. Dr. Yeo shares his journey from studying the genetics of Japanese pufferfish to becoming a leading voice in obesity research and science communication. Whether he's decoding how Ozempic works or reflecting on the importance of good science communication, Dr. Yeo's passion for the field—and his knack for making complex topics relatable—shines through. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague. Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.
Watch the video version of this podcast episode. --------------------------------- Become a #DrGPCR Ecosystem Member --------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. --------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
References Nature Communications 2023.volume 14. Article number: 794 Guerra, DJ.2024 Lecture notes Mozart, WA. 1781. Serenade in B Flat " Gran Partita" K.361 https://youtu.be/BbjpuMid8DE?si=52qNaebE0gZcVK-h --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
References Biochemistry 1996 Feb 13;35(6):1904-10 Nature Communications 2023. volume 14,794 Canti per la Liturgia. Various Artists https://open.spotify.com/album/57EkvfRf0TDt5E7k92xZsa?si=616VsnS9SFCbnSUOKHpouA --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
References Biomolecules. 2020 Jul 7;10(7):1008. FEBS Lett 2021.595, Issue8. Pages 1107-1131 Cell Res. 2022 Mar 2;32(4):327–328. Cell Chem Biol.2024 Jul 18;31(7):1264-1276.e7.Peterson &Lesh. 1974. "Unbroken Chain" on [Live from the Mars Hotel} lp Grateful Dead https://youtu.be/T5FN06LFfHk?si=RgFd7kBKAAJ6YKK0 Hunter&Lesh1970 "Box of Rain" on [American Beauty] lp. https://youtu.be/nxjvo4BRf-Y?si=e9MyF6FdLM2ylZaG Schubert, F. 1826. (Liszt Variation thereof.). ""Standchen.D889. https://youtu.be/9h35VSz2Kkc?si=ch4W4TX9iefj0t1C --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support
Joining us in this episode to discuss all things pharmacology is Bryan Roth. Brian is the Michael Hooker Distinguished Professor of Protein Therapeutics and Translational Proteomics at the University of North Carolina School of Medicine. With discoveries and inventions in the areas of GPCR structure and molecular pharmacology, Bryan is one of the leading figures in the North Carolina pharmacological community. Bryan has been interested in psychedelics and psychoactive drugs since he was young, and as he pursued pharmacological research, he is determined to find the “healing magic'' of these substances for the benefit of mental health… Click play to explore: How brain receptors interact with different psychoactive drugs. What psychoactive drugs actually are, and the different substances that fall under this umbrella. The role psychedelics can play in therapeutic purposes. The unanswered questions surrounding psychedelic research. While psychoactive drugs certainly have a stigma surrounding them, there is no question that there can be beneficial medical uses for them. In this episode, we investigate what these applications look like, and how researchers are progressing the way we use psychoactive drugs. To find out more about Bryan and his research, click here now! Episode also available on Apple Podcasts: http://apple.co/30PvU9
Dr Luca Turin is a biophysicist, writer, and perfume connoisseur whose work on fragrances seems to suggest that we don't smell molecules, per se - we smell the complex vibrations of an atomic structure. Turin came to be convinced of this model for olfaction at the expense of the standard model of receptors binding smell molecules just on the basis of their shape due to a prediction he made about the smell of sulfur. If the pungent odor of rotten eggs and brimstone was due to the vibrational frequency of the sulfur atom attached to the molecule, then any other atom with a similar vibrational frequency, no matter its shape, should also smell of sulfur. He found a compatible molecule in an unexpected place, and the rest fell into place. We talk about his nascent passion for perfumes, why people are so reluctant to smell things, and the overlap between smell, resonance, and consciousness. Sign up for our Patreon and get episodes early + join our weekly Patron Chat https://bit.ly/3lcAasB AND rock some Demystify Gear to spread the word: https://demystifysci.myspreadshop.com/ OR support us when you do your Amazon shopping through this link for Dr. Turin's books: https://amzn.to/4fLMbQR (00:00:00) Go!! (00:05:12) The Concept of Fragrance (00:11:39) Evolution and Decline of Vibrational Theory in Smell Science (00:23:47) Social Dynamics in Scientific Progress (00:26:30) Impact of Public Perception on Scientific Discourse (00:29:23) Musical Analogies in Smell Perception (00:31:00) Harmonic Analogies in Molecular Structures (00:33:17) Exploring Dissonance in Perfumery and Music (00:39:06) Longevity of Perfumes and Environmental Factors (00:46:44) Theory development on molecular vibration and smell perception (00:48:23) Discovery of Boron hydrides and their olfactory similarities to sulfur (00:51:36) Public reception and impact of the vibrational theory of smell (01:11:20) Electrical properties of molecules in drug design (01:13:09) Radical formation and drug interaction with receptors (01:18:05) Electrical vs. shape-based theories in GPCR activation (01:24:21) Electron transfer in cellular metabolism (01:31:11) ATP synthesis and electrostatic gradients in mitochondria (01:34:36) Electrons' Spin Behavior in Biology (01:37:05) Revolution in General Anesthesia (01:42:05) Mechanism of Anesthesia and Brain Function (01:49:23) Quantum Effects in Brain Function (01:57:40) Brain Stimulation and Consciousness (01:58:52) Spin and Conductivity (02:05:02) Radio Frequency Emission from Brain Activity (02:09:54) Mitochondrial Activity and Brain Function (02:18:09) Quantum Aspects in Brain Function (02:21:08) The Intersection of Quantum Mechanics and Consciousness (02:25:01) Historical and Technological Influences on Consciousness Studies (02:30:13) Quantum Biology: Origins and Evolution (02:34:26) The Central Role of Chemistry in Quantum Biology (02:37:11) Transactional Interpretation of Quantum Mechanics (02:44:15) Philosophical indifference to facts (02:45:22) Science as myth-making (02:46:15) Finding joy in science #sciencepodcast, #longformpodcast, #QuantumMechanics, #PhysicsPodcast, #TransactionalInterpretation, #WaveFunctionCollapse, #Schrödinger, #Heisenberg, #QuantumTheory, #Cosmology, #StringTheory, #QuantumPhysics, #TimeReversal, #NonLocality, #QuantumInterpretation, #CarverMead, #MitochondrialResearch, #AntiAgingScience, #EnergyTransactions, #QuantumPhilosophy, #CosmologicalTheories, #QuantumBeats PODCAST INFO: Anastasia completed her PhD studying bioelectricity at Columbia University. When not talking to brilliant people or making movies, she spends her time painting, reading, and guiding backcountry excursions. Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities. MUSIC: -Shilo Delay: https://g.co/kgs/oty671
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Read the full version of the newsletter HERE: https://www.ecosystem.drgpcr.com/dr-gpcr-newsletter/24-06-dr-gpcr-newsletter ------------------------------------------- How can Users benefit Dr. GPCR Ecosystem? https://www.ecosystem.drgpcr.com/explore-individuals ------------------------------------------- How can Organizations benefit from Dr. GPCR Ecosystem? https://www.ecosystem.drgpcr.com/explore-organizations ------------------------------------------- Become a #DrGPCR Ecosystem Member https://www.ecosystem.drgpcr.com/plans-pricing ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. To build our #GPCR Ecosystem, we created various enabling outlets. Individuals https://www.ecosystem.drgpcr.com/explore-individuals Organizations https://www.ecosystem.drgpcr.com/explore-organizations ------------------------------------------- Are you a #GPCR professional? - Subscribe to #DrGPCR monthly newsletter http://www.drgpcr.com/newsletter/ - Listen and subscribe to #DrGPCR Podcasts http://www.drgpcr.com/podcast/ - Listen and watch GPCR-focused scientific talks at #VirtualCafe https://www.drgpcr.com/virtual-cafe/
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
To read the full #DrGPCRNewsletter click here: https://www.ecosystem.drgpcr.com/dr-gpcr-newsletter/24-03-dr-gpcr-newsletter ------------------------------------------- How can Users benefit Dr. GPCR Ecosystem? https://www.ecosystem.drgpcr.com/explore-individuals ------------------------------------------- How can Organizations benefit from Dr. GPCR Ecosystem? https://www.ecosystem.drgpcr.com/explore-organizations ------------------------------------------- Become a #DrGPCR Ecosystem Member https://www.ecosystem.drgpcr.com/plans-pricing ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. To build our #GPCR Ecosystem, we created various enabling outlets. Individuals https://www.ecosystem.drgpcr.com/explore-individuals Organizations https://www.ecosystem.drgpcr.com/explore-organizations ------------------------------------------- Are you a #GPCR professional? - Subscribe to #DrGPCR monthly newsletter http://www.drgpcr.com/newsletter/ - Listen and subscribe to #DrGPCR Podcasts http://www.drgpcr.com/podcast/ - Listen and watch GPCR-focused scientific talks at #VirtualCafe https://www.drgpcr.com/virtual-cafe/
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Synopsis: In this episode of the Biotech 2050 podcast, host Rahul Chaturvedi engages in a thought-provoking conversation with Ray Stevens, a prominent figure in the biotech industry who co-founded Structure Therapeutics. Ray's extensive experience and pivotal role in advancing structure-based drug discovery make him a compelling guest for biotech entrepreneurs seeking to navigate the challenges of entrepreneurship and funding strategies. The episode delves into Ray's journey as a serial entrepreneur, the evolution of structure-based drug discovery, and the strategies employed by Structure Therapeutics to drive innovation and create impactful treatments for global health challenges. Ray's insights into the changing funding environment, the impact of distributed teams on value creation, and the significance of shared passion and mission in a company's success offer valuable knowledge for industry professionals and entrepreneurs. His reflections on the industry's future trends and the personal growth aspect add a relatable and human element to the discussion, making it a valuable resource for individuals at all career stages. Biography: Dr. Stevens helped pioneer the field of structure-based drug discovery. He has been involved in the discovery and development of several therapeutic molecules that have become breakthrough drugs including Palnziq™, which was developed at BioMarin Pharmaceutical and approved in 2018 to treat phenylketonuria. Dr. Stevens also founded Receptos which developed Zeposia™—a GPCR agonist targeting the S1PR1 receptor approved in 2020 for multiple sclerosis and 2021 for ulcerative colitis. Prior to Structure, Dr. Stevens founded the Bridge Institute at the University of Southern California (USC), and the iHuman Institute at ShanghaiTech University. He was previously a tenured chaired chemistry professor at Scripps Research and before that, an assistant professor of chemistry at the University of California, Berkeley. Dr. Stevens' laboratory and students have launched several successful biotech startups including Syrrx (acquired by Takeda), MemRx (acquired by Chiron/Novartis), Receptos (acquired by Celgene/BMS), and RuiYi (now Bird Rock Bio). A prolific scholar, Dr. Stevens has authored more than 400 peer-reviewed publications and received several academic and industry awards. Dr. Stevens conducted postdoctoral research in structural biology at Harvard University with William Lipscomb, who was awarded the Nobel Prize for Chemistry in 1976. Dr. Stevens earned his Ph.D. in chemistry from USC with Robert Bau and George Olah, the latter of whom received the Nobel Prize for Chemistry in 1994. He completed his undergraduate degree in chemistry from the University of Southern Maine.
Today, I sat down with Dr. Brian Kobilka, Professor in the Department of Molecular and Cellular Physiology at Stanford University School of Medicine. Dr. Kobilka is an expert on a class of receptors called G protein-coupled receports, or GPCRs, that are essential in a majority of biological processes including light, flavor, and odor perception and in the activity of adrenalin, dopamine, and serotonin. In fact, currently approximately half of all pharmaceuticals on the market target GPCRs. In the mid 1980s Dr. Kobilka and his colleagues from the Robert Lefkowitz lab were the first to clone the gene for an important GPCR called the beta2-adrenergic receptor, and later he and his collaborators were the first to determine its molecular structure, which served as the basis for understanding all subsequent GPCRs and creating drugs to target them. This work proved to be revolutionary in many areas of science and medicine, such that in 2012, Kobilka was awarded the Nobel Prize in Chemistry for his contributions to understanding GPCRs. In this interview, we talk about these amazing findings and the recent advances in understanding this important class of receptors. Title music: World Is Holding Hands by WinnieTheMoog https://creativecommons.org/licenses/by/4.0/legalcode
To read the full #DrGPCRNewsletter click here: https://www.ecosystem.drgpcr.com/dr-gpcr-newsletter/24-03-dr-gpcr-newsletter ------------------------------------------- How can Users benefit Dr. GPCR Ecosystem? https://www.ecosystem.drgpcr.com/explore-individuals ------------------------------------------- How can Organizations benefit from Dr. GPCR Ecosystem? https://www.ecosystem.drgpcr.com/explore-organizations ------------------------------------------- Become a #DrGPCR Ecosystem Member https://www.ecosystem.drgpcr.com/plans-pricing ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of #GPCR's. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. To build our #GPCR Ecosystem, we created various enabling outlets. Individuals https://www.ecosystem.drgpcr.com/explore-individuals Organizations https://www.ecosystem.drgpcr.com/explore-organizations ------------------------------------------- Are you a #GPCR professional? - Subscribe to #DrGPCR monthly newsletter http://www.drgpcr.com/newsletter/ - Listen and subscribe to #DrGPCR Podcasts http://www.drgpcr.com/podcast/ - Listen and watch GPCR-focused scientific talks at #VirtualCafe https://www.drgpcr.com/virtual-cafe/
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Watch the video version of this podcast episode. ------------------------------------------- Become a #DrGPCR Ecosystem Member ------------------------------------------- Imagine a world in which the vast majority of us are healthy. The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of # GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together. ------------------------------------------- To build our #GPCR Ecosystem, we created various enabling outlets. Individuals Organizations ------------------------------------------- Are you a #GPCR professional? Subscribe to #DrGPCR Monthly Newsletter Listen and subscribe to #DrGPCR Podcasts Listen and watch GPCR-focused scientific talks at #VirtualCafe.
Weight loss drugs are taking center spotlight, but other developing treatments could change how we live. Deidre Woollard caught up with Motley Fool biotech analyst Karl Thiel to discuss: - Biogen's next shot at an Alzheimer's treatment. - Why companies can't “muscle their way” into making new molecules. - How NVIDIA could change drug development. - Moderna's vaccine strategy Companies discussed: LLY, NVO, GPCR, NVDA, DXCM, NVDA, BIIB, GEHC, MRNA, NVCR, VRTX Host: Deidre Woollard Guest: Karl Thiel Producer: Ricky Mulvey Engineer: Tim Sparks Learn more about your ad choices. Visit megaphone.fm/adchoices
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